Maria Teresa Ochoa, MD

TitleAssociate Professor of Clinical Dermatology
InstitutionUniversity of Southern California
AddressHC4 2000 1450 San Pablo
Health Sciences Campus
Los Angeles CA 90089-9176
Phone+1 323 442 6200
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    Dr. Ochoa is an Associate Clinical Professor of Dermatology at the Keck School of Medicine USC. She recently joined the Department of Dermatology at Keck Medicine of USC after 10 years of practice at the UCLA Division of Dermatology.

    Dr. Ochoa is a member of the American Academy of Dermatology, the Society for Investigative Dermatology and California Dermatologic Society. Dr. Ochoa sees patients in the private practice settings at Keck Medicine of USC – Beverly Hills, and Healthcare Consultation Center II on the USC Health Sciences Campus, and participates in the care of the uninsured at the LAC+USC Medical Center. She serves as the Director of the Hansen’s clinic.

    Dr. Ochoa provides dermatology services for the diagnosis and treatment of a broad range of general skin diseases such as acne, eczema, skin cancer and psoriasis, among others. Her clinical and research interest center around infectious diseases of the skin, including the diagnosis and treatment of patients with skin manifestations of HIV, tropical dermatology (skin infectious diseases acquired abroad) and sexually transmitted diseases.

    Dr. Ochoa has a special research interest in the immunologic mechanism of the host response in infectious diseases of the skin.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Teles RMB, Kelly-Scumpia KM, Sarno EN, Rea TH, Ochoa M, Cheng G, Modlin RL. IL-27 Suppresses Antimicrobial Activity in Human Leprosy. J Invest Dermatol. 2015 Oct; 135(10):2410-2417. PMID: 26030183; PMCID: PMC4567935.
    2. Preza GC, Yang OO, Elliott J, Anton PA, Ochoa M. T lymphocyte density and distribution in human colorectal mucosa, and inefficiency of current cell isolation protocols. PLoS One. 2015; 10(4):e0122723. PMID: 25856343; PMCID: PMC4391713.
    3. Kamath S, Vaccaro SA, Rea TH, Ochoa M. Recognizing and managing the immunologic reactions in leprosy. J Am Acad Dermatol. 2014 Oct; 71(4):795-803. PMID: 24767732.
      View in: PubMed
    4. Preza GC, Tanner K, Elliott J, Yang OO, Anton PA, Ochoa M. Antigen-presenting cell candidates for HIV-1 transmission in human distal colonic mucosa defined by CD207 dendritic cells and CD209 macrophages. AIDS Res Hum Retroviruses. 2014 Mar; 30(3):241-9. PMID: 24134315; PMCID: PMC3938918.
    5. Schenk M, Krutzik SR, Sieling PA, Lee DJ, Teles RM, Ochoa M, Komisopoulou E, Sarno EN, Rea TH, Graeber TG, Kim S, Cheng G, Modlin RL. NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nat Med. 2012 Mar 25; 18(4):555-63. PMID: 22447076; PMCID: PMC3348859.
    6. Farshidi D, Craft N, Ochoa M. Mobile teledermatology: As doctors and patients are increasingly mobile, technology keeps us connected. Skinmed. 2011 Jul-Aug; 9(4):231-8. PMID: 21980708.
      View in: PubMed
    7. Ochoa M, Teles R, Haas BE, Zaghi D, Li H, Sarno EN, Rea TH, Modlin RL, Lee DJ. A role for interleukin-5 in promoting increased immunoglobulin M at the site of disease in leprosy. Immunology. 2010 Nov; 131(3):405-14. PMID: 20561085; PMCID: PMC2996561.
    8. Ezra N, Ochoa M, Craft N. Human immunodeficiency virus and leishmaniasis. J Glob Infect Dis. 2010 Sep; 2(3):248-57. PMID: 20927287; PMCID: PMC2946682.
    9. Teles RM, Krutzik SR, Ochoa M, Oliveira RB, Sarno EN, Modlin RL. Interleukin-4 regulates the expression of CD209 and subsequent uptake of Mycobacterium leprae by Schwann cells in human leprosy. Infect Immun. 2010 Nov; 78(11):4634-43. PMID: 20713631; PMCID: PMC2976321.
    10. Zaghi D, Panosian C, Gutierrez MA, Gregson A, Taylor E, Ochoa M. New World cutaneous leishmaniasis: current challenges in diagnosis and parenteral treatment. J Am Acad Dermatol. 2011 Mar; 64(3):587-92. PMID: 20494480.
      View in: PubMed
    11. Lee DJ, Li H, Ochoa M, Tanaka M, Carbone RJ, Damoiseaux R, Burdick A, Sarno EN, Rea TH, Modlin RL. Integrated pathways for neutrophil recruitment and inflammation in leprosy. J Infect Dis. 2010 Feb 15; 201(4):558-69. PMID: 20070238; PMCID: PMC2811231.
    12. Montoya D, Cruz D, Teles RM, Lee DJ, Ochoa M, Krutzik SR, Chun R, Schenk M, Zhang X, Ferguson BG, Burdick AE, Sarno EN, Rea TH, Hewison M, Adams JS, Cheng G, Modlin RL. Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell Host Microbe. 2009 Oct 22; 6(4):343-53. PMID: 19837374; PMCID: PMC2764558.
    13. Ribas A, Comin-Anduix B, Chmielowski B, Jalil J, de la Rocha P, McCannel TA, Ochoa M, Seja E, Villanueva A, Oseguera DK, Straatsma BR, Cochran AJ, Glaspy JA, Hui L, Marincola FM, Wang E, Economou JS, Gomez-Navarro J. Dendritic cell vaccination combined with CTLA4 blockade in patients with metastatic melanoma. Clin Cancer Res. 2009 Oct 01; 15(19):6267-76. PMID: 19789309; PMCID: PMC2765061.
    14. Cruz D, Watson AD, Miller CS, Montoya D, Ochoa M, Sieling PA, Gutierrez MA, Navab M, Reddy ST, Witztum JL, Fogelman AM, Rea TH, Eisenberg D, Berliner J, Modlin RL. Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy. J Clin Invest. 2008 Aug; 118(8):2917-28. PMID: 18636118; PMCID: PMC2467381.
    15. Ochoa M, Loncaric A, Krutzik SR, Becker TC, Modlin RL. "Dermal dendritic cells" comprise two distinct populations: CD1+ dendritic cells and CD209+ macrophages. J Invest Dermatol. 2008 Sep; 128(9):2225-31. PMID: 18337829; PMCID: PMC2682223.
    16. Lee DJ, Sieling PA, Ochoa M, Krutzik SR, Guo B, Hernandez M, Rea TH, Cheng G, Colonna M, Modlin RL. LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells. J Immunol. 2007 Dec 15; 179(12):8128-36. PMID: 18056355; PMCID: PMC2650749.
    17. Niazi KR, Ochoa M, Sieling PA, Rooke NE, Peter AK, Mollahan P, Dickey M, Rabizadeh S, Rea TH, Modlin RL. Activation of human CD4+ T cells by targeting MHC class II epitopes to endosomal compartments using human CD1 tail sequences. Immunology. 2007 Dec; 122(4):522-31. PMID: 17635609; PMCID: PMC2266034.
    18. Sieling PA, Legaspi A, Ochoa M, Rea TH, Modlin RL. Regulation of human T-cell homing receptor expression in cutaneous bacterial infection. Immunology. 2007 Apr; 120(4):518-25. PMID: 17343614; PMCID: PMC2265905.
    19. Sabet S, Ochoa M, Sieling PA, Rea TH, Modlin RL. Functional characterization of a T-cell receptor BV6+ T-cell clone derived from a leprosy lesion. Immunology. 2007 Mar; 120(3):354-61. PMID: 17140401; PMCID: PMC2265884.
    20. Tan BH, Meinken C, Bastian M, Bruns H, Legaspi A, Ochoa M, Krutzik SR, Bloom BR, Ganz T, Modlin RL, Stenger S. Macrophages acquire neutrophil granules for antimicrobial activity against intracellular pathogens. J Immunol. 2006 Aug 01; 177(3):1864-71. PMID: 16849498.
      View in: PubMed
    21. Renn CN, Sanchez DJ, Ochoa M, Legaspi AJ, Oh CK, Liu PT, Krutzik SR, Sieling PA, Cheng G, Modlin RL. TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response. J Immunol. 2006 Jul 01; 177(1):298-305. PMID: 16785525.
      View in: PubMed
    22. Hornell TM, Burster T, Jahnsen FL, Pashine A, Ochoa M, Harding JJ, Macaubas C, Lee AW, Modlin RL, Mellins ED. Human dendritic cell expression of HLA-DO is subset specific and regulated by maturation. J Immunol. 2006 Mar 15; 176(6):3536-47. PMID: 16517722.
      View in: PubMed
    23. Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, Ochoa M, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zügel U, Gallo RL, Eisenberg D, Hewison M, Hollis BW, Adams JS, Bloom BR, Modlin RL. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science. 2006 Mar 24; 311(5768):1770-3. PMID: 16497887.
      View in: PubMed
    24. Krutzik SR, Tan B, Li H, Ochoa M, Liu PT, Sharfstein SE, Graeber TG, Sieling PA, Liu YJ, Rea TH, Bloom BR, Modlin RL. TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells. Nat Med. 2005 Jun; 11(6):653-60. PMID: 15880118; PMCID: PMC1409736.
    25. Tierney E, Ochoa M, Rudkin G, Soriano TT. Mohs' micrographic surgery of a proliferating trichilemmal tumor in a young black man. Dermatol Surg. 2005 Mar; 31(3):359-63. PMID: 15841643.
      View in: PubMed
    26. Hunger RE, Sieling PA, Ochoa M, Sugaya M, Burdick AE, Rea TH, Brennan PJ, Belisle JT, Blauvelt A, Porcelli SA, Modlin RL. Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells. J Clin Invest. 2004 Mar; 113(5):701-8. PMID: 14991068; PMCID: PMC351318.
    27. Bleharski JR, Li H, Meinken C, Graeber TG, Ochoa M, Yamamura M, Burdick A, Sarno EN, Wagner M, Röllinghoff M, Rea TH, Colonna M, Stenger S, Bloom BR, Eisenberg D, Modlin RL. Use of genetic profiling in leprosy to discriminate clinical forms of the disease. Science. 2003 Sep 12; 301(5639):1527-30. PMID: 12970564.
      View in: PubMed
    28. Krutzik SR, Ochoa M, Sieling PA, Uematsu S, Ng YW, Legaspi A, Liu PT, Cole ST, Godowski PJ, Maeda Y, Sarno EN, Norgard MV, Brennan PJ, Akira S, Rea TH, Modlin RL. Activation and regulation of Toll-like receptors 2 and 1 in human leprosy. Nat Med. 2003 May; 9(5):525-32. PMID: 12692544.
      View in: PubMed
    29. Oliveira RB, Ochoa M, Sieling PA, Rea TH, Rambukkana A, Sarno EN, Modlin RL. Expression of Toll-like receptor 2 on human Schwann cells: a mechanism of nerve damage in leprosy. Infect Immun. 2003 Mar; 71(3):1427-33. PMID: 12595460; PMCID: PMC148832.
    30. Ochoa M, Legaspi AJ, Hatziris Z, Godowski PJ, Modlin RL, Sieling PA. Distribution of Toll-like receptor 1 and Toll-like receptor 2 in human lymphoid tissue. Immunology. 2003 Jan; 108(1):10-5. PMID: 12519297; PMCID: PMC1782859.
    31. Kim J, Ochoa M, Krutzik SR, Takeuchi O, Uematsu S, Legaspi AJ, Brightbill HD, Holland D, Cunliffe WJ, Akira S, Sieling PA, Godowski PJ, Modlin RL. Activation of toll-like receptor 2 in acne triggers inflammatory cytokine responses. J Immunol. 2002 Aug 01; 169(3):1535-41. PMID: 12133981; PMCID: PMC4636337.
    32. García VE, Quiroga MF, Ochoa M, Ochoa L, Pasquinelli V, Fainboim L, Olivares LM, Valdez R, Sordelli DO, Aversa G, Modlin RL, Sieling PA. Signaling lymphocytic activation molecule expression and regulation in human intracellular infection correlate with Th1 cytokine patterns. J Immunol. 2001 Nov 15; 167(10):5719-24. PMID: 11698444.
      View in: PubMed
    33. Palacios R, Osorio LE, Grajalew LF, Ochoa M. Treatment failure in children in a randomized clinical trial with 10 and 20 days of meglumine antimonate for cutaneous leishmaniasis due to Leishmania viannia species. Am J Trop Med Hyg. 2001 Mar-Apr; 64(3-4):187-93. PMID: 11442216.
      View in: PubMed
    34. Thoma-Uszynski S, Stenger S, Takeuchi O, Ochoa M, Engele M, Sieling PA, Barnes PF, Rollinghoff M, Bolcskei PL, Wagner M, Akira S, Norgard MV, Belisle JT, Godowski PJ, Bloom BR, Modlin RL. Induction of direct antimicrobial activity through mammalian toll-like receptors. Science. 2001 Feb 23; 291(5508):1544-7. PMID: 11222859.
      View in: PubMed
    35. Ochoa M, Stenger S, Sieling PA, Thoma-Uszynski S, Sabet S, Cho S, Krensky AM, Rollinghoff M, Nunes Sarno E, Burdick AE, Rea TH, Modlin RL. T-cell release of granulysin contributes to host defense in leprosy. Nat Med. 2001 Feb; 7(2):174-9. PMID: 11175847.
      View in: PubMed
    36. Ochoa M, Thoma-Uszynski S, Sieling PA, Sabet S, Cho S, Krensky AM, Burdick A, Rea TH, Modlin RL. Role of granulysin in immunity to leprosy. Lepr Rev. 2000 Dec; 71 Suppl:S115; discussion S115-6. PMID: 11201866.
      View in: PubMed
    37. Thoma-Uszynski S, Kiertscher SM, Ochoa M, Bouis DA, Norgard MV, Miyake K, Godowski PJ, Roth MD, Modlin RL. Activation of toll-like receptor 2 on human dendritic cells triggers induction of IL-12, but not IL-10. J Immunol. 2000 Oct 01; 165(7):3804-10. PMID: 11034386.
      View in: PubMed
    38. Sieling PA, Ochoa M, Jullien D, Leslie DS, Sabet S, Rosat JP, Burdick AE, Rea TH, Brenner MB, Porcelli SA, Modlin RL. Evidence for human CD4+ T cells in the CD1-restricted repertoire: derivation of mycobacteria-reactive T cells from leprosy lesions. J Immunol. 2000 May 01; 164(9):4790-6. PMID: 10779786.
      View in: PubMed
    39. Palacios R, Osorio LE, Giraldo LE, Torres AJ, Philipp MT, Ochoa M. Positive IgG Western blot for Borrelia burgdorferi in Colombia. Mem Inst Oswaldo Cruz. 1999 Jul-Aug; 94(4):499-503. PMID: 10446009.
      View in: PubMed
    40. García VE, Uyemura K, Sieling PA, Ochoa M, Morita CT, Okamura H, Kurimoto M, Rea TH, Modlin RL. IL-18 promotes type 1 cytokine production from NK cells and T cells in human intracellular infection. J Immunol. 1999 May 15; 162(10):6114-21. PMID: 10229854.
      View in: PubMed
    41. Osorio LE, Castillo CM, Ochoa M. Mucosal leishmaniasis due to Leishmania (Viannia) panamensis in Colombia: clinical characteristics. Am J Trop Med Hyg. 1998 Jul; 59(1):49-52. PMID: 9684627.
      View in: PubMed
    42. Osorio LE, Palacios R, Chica ME, Ochoa M. Treatment of cutaneous leishmaniasis in Colombia with dapsone. Lancet. 1998 Feb 14; 351(9101):498-9. PMID: 9482449.
      View in: PubMed
    43. Zea AH, Ochoa M, Ghosh P, Longo DL, Alvord WG, Valderrama L, Falabella R, Harvey LK, Saravia N, Moreno LH, Ochoa AC. Changes in expression of signal transduction proteins in T lymphocytes of patients with leprosy. Infect Immun. 1998 Feb; 66(2):499-504. PMID: 9453602; PMCID: PMC107934.
    44. Ochoa M, Valderrama L, Ochoa A, Zea A, Escobar CE, Moreno LH, Falabella R. Lepromatous and tuberculoid leprosy: clinical presentation and cytokine responses. Int J Dermatol. 1996 Nov; 35(11):786-90. PMID: 8915730.
      View in: PubMed
    45. Restrepo A, Cano LE, Ochoa M. A yeast-derived antigen from Paracoccidioides brasiliensis useful for serologic testing. Sabouraudia. 1985 Feb; 23(1):23-9. PMID: 3922069.
      View in: PubMed
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