Lori Walker, MD

Title(s)Clinical Assistant Professor of Family Medicine (Practitioner) (Part-Time)
SchoolKeck School of Medicine of Usc
AddressESH 244
University Park Campus
Los Angeles CA 90089-3261
Phone+1 213 740 9355
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    Lori Walker, MD received her medical degree from the Charles R. Drew University of California, Los Angeles. She served her residency in Internal Medicine at the Martin Luther King Hospital and is board-certified in Internal Medicine. She is a member of the American College of Physicians.

    Collapse Research 
    Collapse Research Activities and Funding
    Biochemical Markers of Progressive Heart Disease
    NIH R21HL104352Apr 1, 2011 - Dec 31, 2012
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Circadian Influences on Myocardial Ischemia-Reperfusion Injury and Heart Failure. Circ Res. 2024 Mar 15; 134(6):675-694. Eckle T, Bertazzo J, Khatua TN, Fatemi Tabatabaei SR, Moori Bakhtiari N, Walker LA, Martino TA. PMID: 38484024.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Enhancing circadian rhythms-the circadian MEGA bundle as novel approach to treat critical illness. Ann Transl Med. 2023 Jun 30; 11(9):319. Prin M, Bertazzo J, Walker LA, Scott B, Eckle T. PMID: 37404989; PMCID: PMC10316098.
      View in: PubMed   Mentions: 3  
    3. Functional and molecular determinants of right ventricular response to severe pulmonary hypertension in a large animal model. Am J Physiol Heart Circ Physiol. 2023 06 01; 324(6):H804-H820. Brown RD, Hunter KS, Li M, Frid MG, Harral J, Krafsur GM, Holt TN, Williams J, Zhang H, Riddle SR, Edwards MG, Kumar S, Hu CJ, Graham BB, Walker LA, Garry FB, Buttrick PM, Lahm T, Kheyfets VO, Hansen KC, Stenmark KR. PMID: 36961489; PMCID: PMC10190846.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    4. Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart. Circulation. 2022 08 30; 146(9):699-714. Zhao Y, Riching AS, Knight WE, Chi C, Broadwell LJ, Du Y, Abdel-Hafiz M, Ambardekar AV, Irwin DC, Proenza C, Xu H, Leinwand LA, Walker LA, Woulfe KC, Bristow MR, Buttrick PM, Song K. PMID: 35862102; PMCID: PMC9427731.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    5. Physiology of the Right Ventricle Across the Lifespan. Front Physiol. 2021; 12:642284. Woulfe KC, Walker LA. PMID: 33737888; PMCID: PMC7960651.
      View in: PubMed   Mentions: 4  
    6. Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Enables Modeling of Human Hypertrophic Cardiomyopathy. Stem Cell Reports. 2021 03 09; 16(3):519-533. Knight WE, Cao Y, Lin YH, Chi C, Bai B, Sparagna GC, Zhao Y, Du Y, Londono P, Reisz JA, Brown BC, Taylor MRG, Ambardekar AV, Cleveland JC, McKinsey TA, Jeong MY, Walker LA, Woulfe KC, D'Alessandro A, Chatfield KC, Xu H, Bristow MR, Buttrick PM, Song K. PMID: 33636116; PMCID: PMC7940251.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    7. Ex vivo Methods for Measuring Cardiac Muscle Mechanical Properties. Front Physiol. 2020; 11:616996. Knight WE, Ali HR, Nakano SJ, Wilson CE, Walker LA, Woulfe KC. PMID: 33488406; PMCID: PMC7820907.
      View in: PubMed   Mentions: 2  
    8. Isoform-specific regulation of HCN4 channels by a family of endoplasmic reticulum proteins. Proc Natl Acad Sci U S A. 2020 07 28; 117(30):18079-18090. Peters CH, Myers ME, Juchno J, Haimbaugh C, Bichraoui H, Du Y, Bankston JR, Walker LA, Proenza C. PMID: 32647060; PMCID: PMC7395510.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    9. (-)-Epicatechin Modulates Mitochondrial Redox in Vascular Cell Models of Oxidative Stress. Oxid Med Cell Longev. 2020; 2020:6392629. Keller A, Hull SE, Elajaili H, Johnston A, Knaub LA, Chun JH, Walker L, Nozik-Grayck E, Reusch JEB. PMID: 32587663; PMCID: PMC7301192.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    10. Increased myocyte calcium sensitivity in end-stage pediatric dilated cardiomyopathy. Am J Physiol Heart Circ Physiol. 2019 12 01; 317(6):H1221-H1230. Nakano SJ, Walker JS, Walker LA, Li X, Du Y, Miyamoto SD, Sucharov CC, Garcia AM, Mitchell MB, Ambardekar AV, Stauffer BL. PMID: 31625780; PMCID: PMC6960778.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    11. Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the Endothelium. Cell Rep. 2019 08 06; 28(6):1471-1484.e11. Oyama Y, Bartman CM, Bonney S, Lee JS, Walker LA, Han J, Borchers CH, Buttrick PM, Aherne CM, Clendenen N, Colgan SP, Eckle T. PMID: 31390562; PMCID: PMC6708043.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    12. The right ventricular fibroblast secretome drives cardiomyocyte dedifferentiation. PLoS One. 2019; 14(8):e0220573. Bruns DR, Tatman PD, Kalkur RS, Brown RD, Stenmark KR, Buttrick PM, Walker LA. PMID: 31374110; PMCID: PMC6677314.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    13. LAMP-2B regulates human cardiomyocyte function by mediating autophagosome-lysosome fusion. Proc Natl Acad Sci U S A. 2019 01 08; 116(2):556-565. Chi C, Leonard A, Knight WE, Beussman KM, Zhao Y, Cao Y, Londono P, Aune E, Trembley MA, Small EM, Jeong MY, Walker LA, Xu H, Sniadecki NJ, Taylor MR, Buttrick PM, Song K. PMID: 30584088; PMCID: PMC6329949.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    14. Marijuana use and short-term outcomes in patients hospitalized for acute myocardial infarction. PLoS One. 2018; 13(7):e0199705. Johnson-Sasso CP, Tompkins C, Kao DP, Walker LA. PMID: 29995914; PMCID: PMC6040751.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    15. Glucagon-like peptide-1 receptor antagonism impairs basal exercise capacity and vascular adaptation to aerobic exercise training in rats. Physiol Rep. 2018 07; 6(13):e13754. Scalzo RL, Knaub LA, Hull SE, Keller AC, Hunter K, Walker LA, Reusch JEB. PMID: 29984491; PMCID: PMC6036104.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    16. Exercise and Pharmacology as Medicine for Cardiovascular Diseases: From Bench to Bedside and Back. Exerc Sport Sci Rev. 2018 01; 46(1):2-3. Bruns DR, Walker LA. PMID: 28902725.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Interleukin-19 is cardioprotective in dominant negative cyclic adenosine monophosphate response-element binding protein-mediated heart failure in a sex-specific manner. World J Cardiol. 2017 Aug 26; 9(8):673-684. Bruns DR, Ghincea AR, Ghincea CV, Azuma YT, Watson PA, Autieri MV, Walker LA. PMID: 28932356; PMCID: PMC5583540.
      View in: PubMed   Mentions: 2  
    18. Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation. Nat Commun. 2016 Mar 04; 7:10830. Horita H, Wysoczynski CL, Walker LA, Moulton KS, Li M, Ostriker A, Tucker R, McKinsey TA, Churchill ME, Nemenoff RA, Weiser-Evans MC. PMID: 26940659; PMCID: PMC5411712.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    19. Differential Mitochondrial Adaptation in Primary Vascular Smooth Muscle Cells from a Diabetic Rat Model. Oxid Med Cell Longev. 2016; 2016:8524267. Keller AC, Knaub LA, McClatchey PM, Connon CA, Bouchard R, Miller MW, Geary KE, Walker LA, Klemm DJ, Reusch JE. PMID: 27034743; PMCID: PMC4737048.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    20. Genetic ablation of interleukin-18 does not attenuate hypobaric hypoxia-induced right ventricular hypertrophy. Am J Physiol Lung Cell Mol Physiol. 2016 Mar 15; 310(6):L542-50. Bruns DR, Buttrick PM, Walker LA. PMID: 26747780; PMCID: PMC4796262.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    21. High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling. Nat Commun. 2015 Sep 10; 6:8243. Zhao Y, Londono P, Cao Y, Sharpe EJ, Proenza C, O'Rourke R, Jones KL, Jeong MY, Walker LA, Buttrick PM, McKinsey TA, Song K. PMID: 26354680; PMCID: PMC4579788.
      View in: PubMed   Mentions: 125     Fields:    Translation:AnimalsCells
    22. Differential Tissue-Specific Function of Adora2b in Cardioprotection. J Immunol. 2015 Aug 15; 195(4):1732-43. Seo SW, Koeppen M, Bonney S, Gobel M, Thayer M, Harter PN, Ravid K, Eltzschig HK, Mittelbronn M, Walker L, Eckle T. PMID: 26136425; PMCID: PMC4576932.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    23. Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction. Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15; 308(2):L158-67. Bruns DR, Brown RD, Stenmark KR, Buttrick PM, Walker LA. PMID: 25416385; PMCID: PMC4338944.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    24. Characterization and validation of new tools for measuring site-specific cardiac troponin I phosphorylation. J Immunol Methods. 2014 Jan 31; 403(1-2):66-71. Thoemmes SF, Stutzke CA, Du Y, Browning MD, Buttrick PM, Walker LA. PMID: 24291343; PMCID: PMC3945064.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    25. Contractile protein phosphorylation predicts human heart disease phenotypes. Am J Physiol Heart Circ Physiol. 2013 Jun 15; 304(12):H1644-50. Walker LA, Fullerton DA, Buttrick PM. PMID: 23564307; PMCID: PMC3680767.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    26. The right ventricle: biologic insights and response to disease: updated. Curr Cardiol Rev. 2013 Feb 01; 9(1):73-81. Walker LA, Buttrick PM. PMID: 23092273; PMCID: PMC3584309.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    27. Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia. Nat Med. 2012 Apr 15; 18(5):774-82. Eckle T, Hartmann K, Bonney S, Reithel S, Mittelbronn M, Walker LA, Lowes BD, Han J, Borchers CH, Buttrick PM, Kominsky DJ, Colgan SP, Eltzschig HK. PMID: 22504483; PMCID: PMC3378044.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansAnimalsCells
    28. Serendipitous discovery of a novel protein signaling mechanism in heart failure. Biochem Biophys Res Commun. 2012 May 11; 421(3):431-5. Vitello AM, Du Y, Buttrick PM, Walker LA. PMID: 22503978; PMCID: PMC3351564.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    29. Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism. Circ Res. 2012 Mar 02; 110(5):739-48. Cavasin MA, Demos-Davies K, Horn TR, Walker LA, Lemon DD, Birdsey N, Weiser-Evans MC, Harral J, Irwin DC, Anwar A, Yeager ME, Li M, Watson PA, Nemenoff RA, Buttrick PM, Stenmark KR, McKinsey TA. PMID: 22282194; PMCID: PMC3682822.
      View in: PubMed   Mentions: 98     Fields:    Translation:AnimalsCells
    30. Temporal expression of miRNAs and mRNAs in a mouse model of myocardial infarction. Physiol Genomics. 2011 Oct 06; 43(19):1087-95. Port JD, Walker LA, Polk J, Nunley K, Buttrick PM, Sucharov CC. PMID: 21771878; PMCID: PMC3217325.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    31. Biochemical and myofilament responses of the right ventricle to severe pulmonary hypertension. Am J Physiol Heart Circ Physiol. 2011 Sep; 301(3):H832-40. Walker LA, Walker JS, Glazier A, Brown DR, Stenmark KR, Buttrick PM. PMID: 21622821; PMCID: PMC3191097.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    32. Incomplete recovery of myocyte contractile function despite improvement of myocardial architecture with left ventricular assist device support. Circ Heart Fail. 2011 Jul; 4(4):425-32. Ambardekar AV, Walker JS, Walker LA, Cleveland JC, Lowes BD, Buttrick PM. PMID: 21540356; PMCID: PMC3407673.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    33. Protein kinase A changes calcium sensitivity but not crossbridge kinetics in human cardiac myofibrils. Am J Physiol Heart Circ Physiol. 2011 Jul; 301(1):H138-46. Walker JS, Walker LA, Margulies K, Buttrick P, de Tombe P. PMID: 21498779; PMCID: PMC3129926.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    34. Tissue procurement strategies affect the protein biochemistry of human heart samples. J Muscle Res Cell Motil. 2011 Mar; 31(5-6):309-14. Walker LA, Medway AM, Walker JS, Cleveland JC, Buttrick PM. PMID: 21184256.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    35. Stage-specific changes in myofilament protein phosphorylation following myocardial infarction in mice. J Mol Cell Cardiol. 2010 Jun; 48(6):1180-6. Walker LA, Walker JS, Ambler SK, Buttrick PM. PMID: 19799909; PMCID: PMC4447307.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    36. The right ventricle: biologic insights and response to disease. Curr Cardiol Rev. 2009 Jan; 5(1):22-8. Walker LA, Buttrick PM. PMID: 20066144; PMCID: PMC2803284.
      View in: PubMed   Mentions: 17     Fields:    
    37. Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation. J Biol Chem. 2009 Feb 20; 284(8):5097-106. Scruggs SB, Hinken AC, Thawornkaiwong A, Robbins J, Walker LA, de Tombe PP, Geenen DL, Buttrick PM, Solaro RJ. PMID: 19106098; PMCID: PMC2643522.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    38. Partial replacement of cardiac troponin I with a non-phosphorylatable mutant at serines 43/45 attenuates the contractile dysfunction associated with PKCepsilon phosphorylation. J Mol Cell Cardiol. 2006 Apr; 40(4):465-73. Scruggs SB, Walker LA, Lyu T, Geenen DL, Solaro RJ, Buttrick PM, Goldspink PH. PMID: 16445938.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    39. Depressed cardiac myofilament function in human diabetes mellitus. Am J Physiol Heart Circ Physiol. 2005 Dec; 289(6):H2478-83. Jweied EE, McKinney RD, Walker LA, Brodsky I, Geha AS, Massad MG, Buttrick PM, de Tombe PP. PMID: 16085678.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    40. Protein kinase Cepsilon overexpression alters myofilament properties and composition during the progression of heart failure. Circ Res. 2004 Aug 20; 95(4):424-32. Goldspink PH, Montgomery DE, Walker LA, Urboniene D, McKinney RD, Geenen DL, Solaro RJ, Buttrick PM. PMID: 15242976.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
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