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Novel Scoring System for Ranking Hematopoietic Stem Cell Transplantation. Clin Transplant. 2024 Nov; 38(11):e15478.
Baxter-Lowe LA, Wang T, Kuxhausen M, Spellman SR, Maiers M, Lee S, Saultz J, Arrieta-Bolaños E, Gadalla SM, Bolon YT, Betts BC. PMID: 39512128.
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HLA diversity in ethnic populations can affect detection of donor-specific antibodies by single antigen beads. Front Immunol. 2023; 14:1287028.
Quon JC, Kaneta K, Fotiadis N, Menteer J, Lestz RM, Weisert M, Baxter-Lowe LA. PMID: 38077376; PMCID: PMC10701672.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Next generation multiplexing for digital PCR using a novel melt-based hairpin probe design. Front Genet. 2023; 14:1272964.
Edwards RL, Takach JE, McAndrew MJ, Menteer J, Lestz RM, Whitman D, Baxter-Lowe LA. PMID: 38028620; PMCID: PMC10667681.
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PubMed Mentions:
1
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Donor chimerism and immune reconstitution following haploidentical transplantation in sickle cell disease. Front Immunol. 2022; 13:1055497.
Chu Y, Talano JA, Baxter-Lowe LA, Verbsky JW, Morris E, Mahanti H, Ayello J, Keever-Taylor C, Johnson B, Weinberg RS, Shi Q, Moore TB, Fabricatore S, Grossman B, van de Ven C, Shenoy S, Cairo MS. PMID: 36569951; PMCID: PMC9780682.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Cell-free DNA as a solid-organ transplant biomarker: technologies and approaches. Biomark Med. 2022 04; 16(5):401-415.
Edwards RL, Menteer J, Lestz RM, Baxter-Lowe LA. PMID: 35195028.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Haploidentical vs sibling, unrelated, or cord blood hematopoietic cell transplantation for acute lymphoblastic leukemia. Blood Adv. 2022 01 11; 6(1):339-357.
Wieduwilt MJ, Metheny L, Zhang MJ, Wang HL, Estrada-Merly N, Marks DI, Al-Homsi AS, Muffly L, Chao N, Rizzieri D, Gale RP, Gadalla SM, Cairo M, Mussetti A, Gore S, Bhatt VR, Patel SS, Michelis FV, Inamoto Y, Badawy SM, Copelan E, Palmisiano N, Kharfan-Dabaja MA, Lazarus HM, Ganguly S, Bredeson C, Diaz Perez MA, Cassaday R, Savani BN, Ballen K, Martino R, Wirk B, Bacher U, Aljurf M, Bashey A, Murthy HS, Yared JA, Aldoss I, Farhadfar N, Liu H, Abdel-Azim H, Waller EK, Solh M, Seftel MD, van der Poel M, Grunwald MR, Liesveld JL, Kamble RT, McGuirk J, Munker R, Cahn JY, Lee JW, Freytes CO, Krem MM, Winestone LE, Gergis U, Nathan S, Olsson RF, Verdonck LF, Sharma A, Ringdén O, Friend BD, Cerny J, Choe H, Chhabra S, Nishihori T, Seo S, George B, Baxter-Lowe LA, Hildebrandt GC, de Lima M, Litzow M, Kebriaei P, Hourigan CS, Abid MB, Weisdorf DJ, Saber W. PMID: 34547770; PMCID: PMC8753217.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Defining and characterizing HLA diversity. Hum Immunol. 2021 07; 82(7):455-456.
Baxter-Lowe LA. PMID: 34059370.
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Humans
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The changing landscape of HLA typing: Understanding how and when HLA typing data can be used with confidence from bench to bedside. Hum Immunol. 2021 Jul; 82(7):466-477.
Baxter-Lowe LA. PMID: 34030895.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Genetics of HLA Peptide Presentation and Impact on Outcomes in HLA-Matched Allogeneic Hematopoietic Cell Transplantation. Transplant Cell Ther. 2021 07; 27(7):591-599.
Story CM, Wang T, Bhatt VR, Battiwalla M, Badawy SM, Kamoun M, Gragert L, Brown V, Baxter-Lowe LA, Marsh SGE, Gadalla SM, Schetelig J, Mytilineos J, Miklos D, Waller EK, Kuxhausen M, Spellman S, Lee S, Paczesny S, Lansford JL, Vincent BG, Riches ML, Armistead PM, Center for International Blood and Marrow Transplant Research Immunobiology Working Committee. PMID: 33882342; PMCID: PMC8343993.
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The discovery of the HLA-B*56:75 allele shows that HLA sequencing is important in all transplant settings. HLA. 2021 05; 97(5):463-464.
Quon JC, Lyle WD, Baxter-Lowe LA. PMID: 33369190.
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Humans
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Growing evidence that 2-field high-resolution HLA typing is important for kidney transplantation. Am J Transplant. 2020 12; 20(12):3277-3278.
Baxter-Lowe LA. PMID: 32484291.
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PubMed Mentions:
1 Fields:
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Optimal Donor for African Americans with Hematologic Malignancy: HLA-Haploidentical Relative or Umbilical Cord Blood Transplant. Biol Blood Marrow Transplant. 2020 10; 26(10):1930-1936.
Solomon SR, Martin AS, Zhang MJ, Ballen K, Bashey A, Battiwalla M, Baxter-Lowe LA, Brunstein C, Chhabra S, Perez MAD, Fuchs EJ, Ganguly S, Hardy N, Hematti P, McGuirk J, Peres E, Ringden O, Rizzieri D, Romee R, Solh M, Szwajcer D, van der Poel M, Waller E, William BM, Eapen M. PMID: 32649981; PMCID: PMC7530013.
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Translation:
Humans
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The clinical impact of donor-specific antibodies on antibody-mediated rejection and long-term prognosis after heart transplantation. Curr Opin Organ Transplant. 2019 06; 24(3):245-251.
Su JA, Baxter-Lowe LA, Kantor PF, Szmuszkovicz JR, Menteer J. PMID: 31090631.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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The safety and efficacy of clofarabine in combination with high-dose cytarabine and total body irradiation myeloablative conditioning and allogeneic stem cell transplantation in children, adolescents, and young adults (CAYA) with poor-risk acute leukemia. Bone Marrow Transplant. 2019 02; 54(2):226-235.
Hochberg J, Zahler S, Geyer MB, Chen N, Krajewski J, Harrison L, Militano O, Ozkaynak MF, Cheerva AC, Talano J, Moore TB, Gillio AP, Walters MC, Baxter-Lowe LA, Hamby C, Cairo MS. PMID: 29899571.
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PubMed Mentions:
3 Fields:
Translation:
HumansCTClinical Trials
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Human leukocyte antigens antibodies after lung transplantation: Primary results of the HALT study. Am J Transplant. 2018 09; 18(9):2285-2294.
Hachem RR, Kamoun M, Budev MM, Askar M, Ahya VN, Lee JC, Levine DJ, Pollack MS, Dhillon GS, Weill D, Schechtman KB, Leard LE, Golden JA, Baxter-Lowe L, Mohanakumar T, Tyan DB, Yusen RD. PMID: 29687961; PMCID: PMC6117197.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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CPRA for allocation of kidneys in the US: More candidates ≥98% CPRA, lower positive crossmatch rates and improved transplant rates for sensitized patients. Hum Immunol. 2016 May; 77(5):395-402.
Baxter-Lowe LA, Kucheryavaya A, Tyan D, Reinsmoen N. PMID: 27012168.
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PubMed Mentions:
7 Fields:
Translation:
HumansPHPublic Health
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A Phase I Study of Reduced-Intensity Conditioning and Allogeneic Stem Cell Transplantation Followed by Dose Escalation of Targeted Consolidation Immunotherapy with Gemtuzumab Ozogamicin in Children and Adolescents with CD33+ Acute Myeloid Leukemia. Biol Blood Marrow Transplant. 2016 Apr; 22(4):698-704.
Zahler S, Bhatia M, Ricci A, Roy S, Morris E, Harrison L, van de Ven C, Fabricatore S, Wolownik K, Cooney-Qualter E, Baxter-Lowe LA, Luisi P, Militano O, Kletzel M, Cairo MS. PMID: 26785332.
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PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia. Pediatr Blood Cancer. 2014 Jul; 61(7):1289-94.
McGuinn C, Geyer MB, Jin Z, Garvin JH, Satwani P, Bradley MB, Bhatia M, George D, Duffy D, Morris E, van de Ven C, Schwartz J, Baxter-Lowe LA, Cairo MS. PMID: 24623601.
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PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
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Identification of a permissible HLA mismatch in hematopoietic stem cell transplantation. Blood. 2014 Feb 20; 123(8):1270-8.
Fernandez-Viña MA, Wang T, Lee SJ, Haagenson M, Aljurf M, Askar M, Battiwalla M, Baxter-Lowe LA, Gajewski J, Jakubowski AA, Marino S, Oudshoorn M, Marsh SG, Petersdorf EW, Schultz K, Turner EV, Waller EK, Woolfrey A, Umejiego J, Spellman SR, Setterholm M. PMID: 24408320; PMCID: PMC3931192.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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Impact of allele-level HLA matching on outcomes after myeloablative single unit umbilical cord blood transplantation for hematologic malignancy. Blood. 2014 Jan 02; 123(1):133-40.
Eapen M, Klein JP, Ruggeri A, Spellman S, Lee SJ, Anasetti C, Arcese W, Barker JN, Baxter-Lowe LA, Brown M, Fernandez-Vina MA, Freeman J, He W, Iori AP, Horowitz MM, Locatelli F, Marino S, Maiers M, Michel G, Sanz GF, Gluckman E, Rocha V, Center for International Blood and Marrow Transplant Research, Netcord, Eurocord, and the European G. PMID: 24141369; PMCID: PMC3879902.
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PubMed Mentions:
88 Fields:
Translation:
HumansCells
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Amino acid substitution at peptide-binding pockets of HLA class I molecules increases risk of severe acute GVHD and mortality. Blood. 2013 Nov 21; 122(22):3651-8.
Pidala J, Wang T, Haagenson M, Spellman SR, Askar M, Battiwalla M, Baxter-Lowe LA, Bitan M, Fernandez-Viña M, Gandhi M, Jakubowski AA, Maiers M, Marino SR, Marsh SG, Oudshoorn M, Palmer J, Prasad VK, Reddy V, Ringden O, Saber W, Santarone S, Schultz KR, Setterholm M, Trachtenberg E, Turner EV, Woolfrey AE, Lee SJ, Anasetti C. PMID: 23982174; PMCID: PMC3837514.
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PubMed Mentions:
41 Fields:
Translation:
HumansCells
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Multiple mismatches at the low expression HLA loci DP, DQ, and DRB3/4/5 associate with adverse outcomes in hematopoietic stem cell transplantation. Blood. 2013 May 30; 121(22):4603-10.
Fernández-Viña MA, Klein JP, Haagenson M, Spellman SR, Anasetti C, Noreen H, Baxter-Lowe LA, Cano P, Flomenberg N, Confer DL, Horowitz MM, Oudshoorn M, Petersdorf EW, Setterholm M, Champlin R, Lee SJ, de Lima M. PMID: 23596045; PMCID: PMC3668493.
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PubMed Mentions:
43 Fields:
Translation:
Humans
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Busulfan, fludarabine, and alemtuzumab conditioning and unrelated cord blood transplantation in children with sickle cell disease. Biol Blood Marrow Transplant. 2013 Apr; 19(4):676-7.
Radhakrishnan K, Bhatia M, Geyer MB, Del Toro G, Jin Z, Baker C, Harrison L, Morris E, Baxter-Lowe LA, Cairo MS. PMID: 23403308.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Transplantation-related mortality, graft failure, and survival after reduced-toxicity conditioning and allogeneic hematopoietic stem cell transplantation in 100 consecutive pediatric recipients. Biol Blood Marrow Transplant. 2013 Apr; 19(4):552-61.
Satwani P, Jin Z, Duffy D, Morris E, Bhatia M, Garvin JH, George D, Bradley MB, Harrison L, Petrillo K, Schwartz J, Foley S, Hawks R, Baxter-Lowe LA, Cairo MS. PMID: 23253557.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Effect of HLA-matching recipients to donor noninherited maternal antigens on outcomes after mismatched umbilical cord blood transplantation for hematologic malignancy. Biol Blood Marrow Transplant. 2012 Dec; 18(12):1890-6.
Rocha V, Spellman S, Zhang MJ, Ruggeri A, Purtill D, Brady C, Baxter-Lowe LA, Baudoux E, Bergamaschi P, Chow R, Freed B, Koegler G, Kurtzberg J, Larghero J, Lecchi L, Nagler A, Navarrette C, Prasad V, Pouthier F, Price T, Ratanatharathorn V, van Rood JJ, Horowitz MM, Gluckman E, Eapen M, Eurocord-European Blood and Marrow Transplant Group and the Center for International Blood and Marro. PMID: 22814031; PMCID: PMC3826155.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Busulfan, fludarabine, and alemtuzumab as a reduced toxicity regimen for children with malignant and nonmalignant diseases improves engraftment and graft-versus-host disease without delaying immune reconstitution. Biol Blood Marrow Transplant. 2012 Nov; 18(11):1656-63.
Law J, Cowan MJ, Dvorak CC, Musick L, Long-Boyle JR, Baxter-Lowe LA, Horn B. PMID: 22609040.
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T cell depletion utilizing CD34(+) stem cell selection and CD3(+) addback from unrelated adult donors in paediatric allogeneic stem cell transplantation recipients. Br J Haematol. 2012 Apr; 157(2):205-19.
Geyer MB, Ricci AM, Jacobson JS, Majzner R, Duffy D, Van de Ven C, Ayello J, Bhatia M, Garvin JH, George D, Satwani P, Harrison L, Morris E, Semidei-Pomales M, Schwartz J, Alobeid B, Baxter-Lowe LA, Cairo MS. PMID: 22313507.
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PubMed Mentions:
11 Fields:
Translation:
HumansCTClinical Trials
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A Phase I study of gemtuzumab ozogamicin (GO) in combination with busulfan and cyclophosphamide (Bu/Cy) and allogeneic stem cell transplantation in children with poor-risk CD33+ AML: a new targeted immunochemotherapy myeloablative conditioning (MAC) regimen. Biol Blood Marrow Transplant. 2012 Feb; 18(2):324-9.
Satwani P, Bhatia M, Garvin JH, George D, Dela Cruz F, Le Gall J, Jin Z, Schwartz J, Duffy D, van de Ven C, Foley S, Hawks R, Morris E, Baxter-Lowe LA, Cairo MS. PMID: 22079471.
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PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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Scoring HLA class I mismatches by HistoCheck does not predict clinical outcome in unrelated hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2012 May; 18(5):739-46.
Spellman S, Klein J, Haagenson M, Askar M, Baxter-Lowe LA, He J, Hsu S, Blasczyk R, Hurley C. PMID: 21963622; PMCID: PMC3270214.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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HLA-DR matching in organ allocation: balance between waiting time and rejection in pediatric kidney transplantation. Arch Surg. 2011 Jul; 146(7):824-9.
Vu LT, Baxter-Lowe LA, Garcia J, McEnhill M, Summers P, Hirose R, Lee M, Stock PG. PMID: 21768429.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Reduced-intensity conditioning allogeneic hematopoietic cell transplantation for patients with hematologic malignancies who relapse following autologous transplantation: a multi-institutional prospective study from the Cancer and Leukemia Group B (CALGB trial 100002). Biol Blood Marrow Transplant. 2011 Apr; 17(4):558-65.
Bashey A, Owzar K, Johnson JL, Edwards PS, Kelly M, Baxter-Lowe LA, Devine S, Farag S, Hurd D, Ball E, McCarthy P, Lister J, Shea TC, Linker C. PMID: 20674758; PMCID: PMC3807877.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Kidney transplantation at UCSF: 8,300 transplants and onward. Clin Transpl. 2010; 161-7.
Wojciechowski D, Hirose R, Stock P, Vincenti F, Baxter-Lowe LA, Salvatierra O. PMID: 21696039.
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Translation:
Humans
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An age-dependent pharmacokinetic study of intravenous and oral mycophenolate mofetil in combination with tacrolimus for GVHD prophylaxis in pediatric allogeneic stem cell transplantation recipients. Biol Blood Marrow Transplant. 2010 Mar; 16(3):333-43.
Bhatia M, Militano O, Jin Z, Figurski M, Shaw L, Moore V, Morris E, Tallamy B, van deVen C, Ayello J, Baxter-Lowe L, Satwani P, George D, Bradley MB, Garvin J, Cairo MS. PMID: 19835971.
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PubMed Mentions:
21 Fields:
Translation:
HumansCTClinical Trials
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HLA-A disparities illustrate challenges for ranking the impact of HLA mismatches on bone marrow transplant outcomes in the United States. Biol Blood Marrow Transplant. 2009 Aug; 15(8):971-81.
Baxter-Lowe LA, Maiers M, Spellman SR, Haagenson MD, Wang T, Fernandez-Vina M, Marsh SG, Horowitz M, Hurley CK. PMID: 19589487; PMCID: PMC2747529.
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PubMed Mentions:
13 Fields:
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Advancement and clinical implications of HLA typing in allogeneic hematopoietic stem cell transplantation. Cancer Treat Res. 2009; 144:71-94.
Baxter-Lowe LA, Hurley CK. PMID: 19779873.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Results of the Cord Blood Transplantation Study (COBLT): clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies. Blood. 2008 Nov 15; 112(10):4318-27.
Kurtzberg J, Prasad VK, Carter SL, Wagner JE, Baxter-Lowe LA, Wall D, Kapoor N, Guinan EC, Feig SA, Wagner EL, Kernan NA, COBLT Steering Committee. PMID: 18723429; PMCID: PMC2581998.
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PubMed Mentions:
102 Fields:
Translation:
HumansCTClinical Trials
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High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation. Blood. 2007 Dec 15; 110(13):4576-83.
Lee SJ, Klein J, Haagenson M, Baxter-Lowe LA, Confer DL, Eapen M, Fernandez-Vina M, Flomenberg N, Horowitz M, Hurley CK, Noreen H, Oudshoorn M, Petersdorf E, Setterholm M, Spellman S, Weisdorf D, Williams TM, Anasetti C. PMID: 17785583.
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PubMed Mentions:
475 Fields:
Translation:
Humans
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A high degree of HLA disparity arises from limited allelic diversity: analysis of 1775 unrelated bone marrow transplant donor-recipient pairs. Hum Immunol. 2007 Jan; 68(1):30-40.
Hurley CK, Fernandez-Vina M, Hildebrand WH, Noreen HJ, Trachtenberg E, Williams TM, Baxter-Lowe LA, Begovich AB, Petersdorf E, Selvakumar A, Stastny P, Hegland J, Hartzman RJ, Carston M, Gandham S, Kollman C, Nelson G, Spellman S, Setterholm M. PMID: 17207710.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome. Blood. 2004 Oct 01; 104(7):1923-30.
Flomenberg N, Baxter-Lowe LA, Confer D, Fernandez-Vina M, Filipovich A, Horowitz M, Hurley C, Kollman C, Anasetti C, Noreen H, Begovich A, Hildebrand W, Petersdorf E, Schmeckpeper B, Setterholm M, Trachtenberg E, Williams T, Yunis E, Weisdorf D. PMID: 15191952.
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PubMed Mentions:
197 Fields:
Translation:
HumansCells