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Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State. Cell Chem Biol. 2018 11 15; 25(11):1389-1402.e9.
Kurnik M, Sahin C, Andersen CB, Lorenzen N, Giehm L, Mohammad-Beigi H, Jessen CM, Pedersen JS, Christiansen G, Petersen SV, Staal R, Krishnamurthy G, Pitts K, Reinhart PH, Mulder FAA, Mente S, Hirst WD, Otzen DE. PMID: 30197194.
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28 Fields:
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HumansCells
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Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides: part II. Bioorg Med Chem. 2010 Jan 01; 18(1):190-201.
Moore WJ, Kern JC, Bhat R, Bodine PV, Fukyama S, Krishnamurthy G, Magolda RL, Pitts K, Stauffer B, Trybulski EJ. PMID: 19932972.
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PubMed Mentions:
11 Fields:
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HumansAnimalsCells
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Small molecule inhibitors of HIV RT Ribonuclease H. Bioorg Med Chem Lett. 2010 Jan 01; 20(1):398-402.
Di Grandi M, Olson M, Prashad AS, Bebernitz G, Luckay A, Mullen S, Hu Y, Krishnamurthy G, Pitts K, O'Connell J. PMID: 19939680.
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PubMed Mentions:
10 Fields:
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HumansCells
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A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation. Bone. 2009 Jun; 44(6):1063-8.
Bodine PV, Stauffer B, Ponce-de-Leon H, Bhat RA, Mangine A, Seestaller-Wehr LM, Moran RA, Billiard J, Fukayama S, Komm BS, Pitts K, Krishnamurthy G, Gopalsamy A, Shi M, Kern JC, Commons TJ, Woodworth RP, Wilson MA, Welmaker GS, Trybulski EJ, Moore WJ. PMID: 19254787.
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PubMed Mentions:
50 Fields:
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HumansAnimalsCells
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Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides. J Med Chem. 2009 Jan 08; 52(1):105-16.
Moore WJ, Kern JC, Bhat R, Commons TJ, Fukayama S, Goljer I, Krishnamurthy G, Magolda RL, Nogle L, Pitts K, Stauffer B, Trybulski EJ, Welmaker GS, Wilson M, Bodine PV. PMID: 19072540.
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23 Fields:
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HumansAnimalsCells
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Theoretical simulation of the electronic circular dichroism spectrum of calicheamicin. Bioorg Med Chem. 2005 Sep 01; 13(17):5072-9.
Giorgio E, Tanaka K, Ding W, Krishnamurthy G, Pitts K, Ellestad GA, Rosini C, Berova N. PMID: 16051103.
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PubMed Mentions:
1 Fields:
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Cells
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Identification and characterization of small molecule modulators of KChIP/Kv4 function. Bioorg Med Chem. 2005 Nov 15; 13(22):6112-9.
Bowlby MR, Chanda P, Edris W, Hinson J, Jow F, Katz AH, Kennedy J, Krishnamurthy G, Pitts K, Ryan K, Zhang H, Greenblatt L. PMID: 16081294.
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11 Fields:
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HumansAnimalsCells
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A re-examination of the circular dichroism of the calicheamicin enediyne/dienone chromophoric interaction. Org Lett. 2004 May 27; 6(11):1801-4.
Ding W, Pitts K, Ellestad GA, Krishnamurthy G. PMID: 15151418.
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Cells