Duke Han, PhD

Title(s)Professor of Family Medicine
SchoolKeck School of Medicine of Usc
AddressHSA Unit22 A-7 7423 1000 S. Fremont Avenue
Off Campus
Alhambra CA 91803
Phone+1 626 457 5858
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    Collapse Biography 
    Collapse Education and Training
    Duke University, Durham, NCBS05/1998Psychology/Neuroscience
    University of Massachusetts Boston, Boston, MAPhD12/2004Clinical Psychology/Neuropsychology
    Collapse Awards and Honors
    International Neuropsychological Society2006Nelson Butters Award
    American Psychological Association2012Division 40 Blue Ribbon Award
    National Institutes of Aging/AFAR2012  - 2017Paul B. Beason Award for Aging Research
    AARP and AgeUK2015  - 2018Global Council on Brain Health Governance Member

    Collapse Overview 
    Collapse Overview
    Dr. Duke Han is a diplomate of the American Board of Professional Psychology in clinical neuropsychology, Director of Neuropsychology in the Department of Family Medicine, and a tenured Professor of Family Medicine, Neurology, Psychology, and Gerontology at the Keck School of Medicine of the University of Southern California. Dr. Han is interested in the study of factors that impact cognition and decision making in aging. He also has special interests in using novel neuroimaging and statistical approaches to better understand these factors. Dr. Han maintains an active research collaboration with the Rush Alzheimer's Disease Center of Rush University Medical Center in Chicago, where he was most recently a tenured faculty member and continues to retain a visiting professor status. He was the recipient of the prestigious Paul B. Beeson Career Development Award in aging research, which is supported by the National Institute on Aging (NIA), the American Federation of Aging Research (AFAR), and the John A. Hartford Foundation. Dr. Han is actively involved in peer-review of aging and Alzheimer’s Disease research grants for the NIH, and is currently serving as the Chair of the NIA Clinical and Translational Research of Aging Review Committee (NIA-T). He reviews manuscripts for over 30 scientific journals and is on the editorial board for the Journal of Alzheimer’s Disease and Archives of Clinical Neuropsychology. Dr. Han is an inaugural Governance Committee member of the Global Council for Brain Health, an independent science collaborative convened by the AARP with support from AgeUK tasked to summarize scientific knowledge regarding brain health topics for the aging public. Dr. Han currently serves as an oral examiner for the clinical neuropsychology board certification process and holds leadership or mentorship roles in the International Neuropsychological Society (INS), the National Academy of Neuropsychology (NAN), the American Academy of Clinical Neuropsychology (AACN), and the Society of Clinical Neuropsychology (Division 40) of the American Psychological Association.
    Collapse Websites

    Collapse Research 
    Collapse Research Activities and Funding
    Finance, Cognition, and Default Network in Aging (FCDNA)
    NIH RF1AG068166May 1, 2021 - Apr 30, 2024
    Role: Principal Investigator
    Racial Differences in Decision Making among Older Adults
    NIH R01AG055430Jul 15, 2017 - Apr 30, 2022
    Role: Principal Investigator
    Neural Correlates of Impaired Financial & Health Care Decision-Making in Old Age
    NIH K23AG040625Aug 15, 2012 - Jul 31, 2017
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Featured Content 
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Self-reported experiences of discrimination in older black adults are associated with insula functional connectivity. Brain Imaging Behav. 2021 Aug; 15(4):1718-1727. Han SD, Lamar M, Fleischman D, Kim N, Bennett DA, Lewis TT, Arfanakis K, Barnes LL. PMID: 32720182; PMCID: PMC7854830.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    2. The search for meaning in preclinical Alzheimer disease clinical trials. Neurology. 2019 07 23; 93(4):139-140. Han SD, Shinotoh H. PMID: 31289145.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Neuropsychological case report of MCI reversion at one-year follow-up. Appl Neuropsychol Adult. 2020 May-Jun; 27(3):284-293. Weissberger G, Gibson K, Nguyen C, Han D. PMID: 30351208.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. White matter correlates of temporal discounting in older adults. Brain Struct Funct. 2018 Nov; 223(8):3653-3663. Han SD, Arfanakis K, Fleischman DA, Yu L, Bennett DA, Boyle PA. PMID: 29992469; PMCID: PMC6379138.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Correction to: Detectable Neuropsychological Differences in Early Preclinical Alzheimer's Disease: a Meta-Analysis. Neuropsychol Rev. 2017 12; 27(4):326-327. Han SD, Nguyen CP, Stricker NH, Nation DA. PMID: 29275535.
      View in: PubMed   Mentions: 5     Fields:    
    6. Detectable Neuropsychological Differences in Early Preclinical Alzheimer's Disease: A Meta-Analysis. Neuropsychol Rev. 2017 12; 27(4):305-325. Duke Han S, Nguyen CP, Stricker NH, Nation DA. PMID: 28497179; PMCID: PMC5681895.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    7. Grey matter correlates of susceptibility to scams in community-dwelling older adults. Brain Imaging Behav. 2016 06; 10(2):524-32. Duke Han S, Boyle PA, Yu L, Arfanakis K, James BD, Fleischman DA, Bennett DA. PMID: 26100658; PMCID: PMC4689662.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    8. Financial literacy is associated with white matter integrity in old age. Neuroimage. 2016 Apr 15; 130:223-229. Han SD, Boyle PA, Arfanakis K, Fleischman D, Yu L, James BD, Bennett DA. PMID: 26899784; PMCID: PMC4808430.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    9. Mild Cognitive Impairment and Susceptibility to Scams in Old Age. J Alzheimers Dis. 2016; 49(3):845-51. Han SD, Boyle PA, James BD, Yu L, Bennett DA. PMID: 26519434; PMCID: PMC4708889.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    10. Age-Associated Financial Vulnerability: An Emerging Public Health Issue. Ann Intern Med. 2015 Dec 01; 163(11):877-8. Lachs MS, Han SD. PMID: 26458261; PMCID: PMC4769872.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    11. Discrepancies between cognition and decision making in older adults. Aging Clin Exp Res. 2016 Feb; 28(1):99-108. Han SD, Boyle PA, James BD, Yu L, Barnes LL, Bennett DA. PMID: 25995167; PMCID: PMC4654982.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    12. Pulse pressure in relation to tau-mediated neurodegeneration, cerebral amyloidosis, and progression to dementia in very old adults. JAMA Neurol. 2015 May; 72(5):546-53. Nation DA, Edmonds EC, Bangen KJ, Delano-Wood L, Scanlon BK, Han SD, Edland SD, Salmon DP, Galasko DR, Bondi MW, Alzheimer’s Disease Neuroimaging Initiative Investigators. PMID: 25822631; PMCID: PMC4428938.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    13. Poorer Financial and Health Literacy Among Community-Dwelling Older Adults With Mild Cognitive Impairment. J Aging Health. 2015 Sep; 27(6):1105-17. Han SD, Boyle PA, James BD, Yu L, Bennett DA. PMID: 25903976; PMCID: PMC4520748.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    14. Mild cognitive impairment is associated with poorer decision-making in community-based older persons. J Am Geriatr Soc. 2015 Apr; 63(4):676-83. Han SD, Boyle PA, James BD, Yu L, Bennett DA. PMID: 25850350; PMCID: PMC4406791.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    15. Cognitive decline is associated with risk aversion and temporal discounting in older adults without dementia. PLoS One. 2015; 10(4):e0121900. James BD, Boyle PA, Yu L, Han SD, Bennett DA. PMID: 25838074; PMCID: PMC4383618.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    16. Financial literacy is associated with medial brain region functional connectivity in old age. Arch Gerontol Geriatr. 2014 Sep-Oct; 59(2):429-38. Han SD, Boyle PA, Yu L, Fleischman DA, Arfanakis K, Leurgans S, Bennett DA. PMID: 24893911; PMCID: PMC4130771.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    17. Ventromedial PFC, parahippocampal, and cerebellar connectivity are associated with temporal discounting in old age. Exp Gerontol. 2013 Dec; 48(12):1489-98. Han SD, Boyle PA, Yu L, Fleischman DA, Arfanakis K, Bennett DA. PMID: 24135750; PMCID: PMC3855854.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    18. Gray-matter macrostructure in cognitively healthy older persons: associations with age and cognition. Brain Struct Funct. 2014 Nov; 219(6):2029-49. Fleischman DA, Leurgans S, Arfanakis K, Arvanitakis Z, Barnes LL, Boyle PA, Han SD, Bennett DA. PMID: 23955313; PMCID: PMC3926914.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    19. Faster cognitive decline in the years prior to MR imaging is associated with smaller hippocampal volumes in cognitively healthy older persons. Front Aging Neurosci. 2013; 5:21. Fleischman DA, Yu L, Arfanakis K, Han SD, Barnes LL, Arvanitakis Z, Boyle PA, Bennett DA. PMID: 23760360; PMCID: PMC3672675.
      View in: PubMed   Mentions: 3  
    20. Executive functions, depressive symptoms, and college adjustment in women. Appl Neuropsychol Adult. 2013; 20(2):136-44. Wingo J, Kalkut E, Tuminello E, Asconape J, Han SD. PMID: 23397999.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Beta amyloid, tau, neuroimaging, and cognition: sequence modeling of biomarkers for Alzheimer's Disease. Brain Imaging Behav. 2012 Dec; 6(4):610-20. Han SD, Gruhl J, Beckett L, Dodge HH, Stricker NH, Farias S, Mungas D, Alzheimer’s Disease Neuroimaging Initiative. PMID: 22648764; PMCID: PMC3582336.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    22. CSF biomarker associations with change in hippocampal volume and precuneus thickness: implications for the Alzheimer's pathological cascade. Brain Imaging Behav. 2012 Dec; 6(4):599-609. Stricker NH, Dodge HH, Dowling NM, Han SD, Erosheva EA, Jagust WJ, Alzheimer’s Disease Neuroimaging Initiative. PMID: 22614327; PMCID: PMC3656503.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    23. Functional connectivity networks associated with chronic musculoskeletal pain in old age. Int J Geriatr Psychiatry. 2013 Aug; 28(8):858-67. Duke Han S, Buchman AS, Arfanakis K, Fleischman DA, Bennett DA. PMID: 23124844; PMCID: PMC3594549.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. Neuropsychological assessment in a case of adult-onset hemophagocytic lymphohistiocytosis (HLH). Clin Neuropsychol. 2012; 26(6):1038-52. Ruppert P, Edmonds EC, Brook M, Musil S, Han SD. PMID: 22784400.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. Functional neuroimaging studies in normal aging. Curr Top Behav Neurosci. 2012; 10:91-111. Guidotti Breting LM, Tuminello ER, Duke Han S. . PMID: 21751096.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    26. Neural intrinsic connectivity networks associated with risk aversion in old age. Behav Brain Res. 2012 Feb 01; 227(1):233-40. Han SD, Boyle PA, Arfanakis K, Fleischman DA, Yu L, Edmonds EC, Bennett DA. PMID: 22044475; PMCID: PMC3242855.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    27. Functional connectivity variations in mild cognitive impairment: associations with cognitive function. J Int Neuropsychol Soc. 2012 Jan; 18(1):39-48. Han SD, Arfanakis K, Fleischman DA, Leurgans SE, Tuminello ER, Edmonds EC, Bennett DA. PMID: 22005016; PMCID: PMC3368801.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    28. Are self-reported symptoms of executive dysfunction associated with objective executive function performance following mild to moderate traumatic brain injury? J Clin Exp Neuropsychol. 2011 Jul; 33(6):704-14. Schiehser DM, Delis DC, Filoteo JV, Delano-Wood L, Han SD, Jak AJ, Drake AI, Bondi MW. PMID: 21958432; PMCID: PMC3325052.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    29. The apolipoprotein e antagonistic pleiotropy hypothesis: review and recommendations. Int J Alzheimers Dis. 2011 Feb 24; 2011:726197. Tuminello ER, Han SD. PMID: 21423560; PMCID: PMC3056453.
      View in: PubMed   Mentions: 54  
    30. Hierarchical cognitive and psychosocial predictors of amnestic mild cognitive impairment. J Int Neuropsychol Soc. 2010 Jul; 16(4):721-9. Han SD, Suzuki H, Jak AJ, Chang YL, Salmon DP, Bondi MW. PMID: 20561399; PMCID: PMC3005198.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Increased 5-HT1B receptor density in the basolateral amygdala of passive observer rats exposed to aggression. Brain Res Bull. 2010 Aug 30; 83(1-2):38-43. Suzuki H, Han SD, Lucas LR. PMID: 20599596.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    32. Complex activities of daily living vary by mild cognitive impairment subtype. J Int Neuropsychol Soc. 2010 Jul; 16(4):630-9. Bangen KJ, Jak AJ, Schiehser DM, Delano-Wood L, Tuminello E, Han SD, Delis DC, Bondi MW. PMID: 20374675; PMCID: PMC2891154.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    33. Chronic passive exposure to aggression decreases D2 and 5-HT 1B receptor densities. Physiol Behav. 2010 Apr 19; 99(5):562-70. Suzuki H, Han SD, Lucas LR. PMID: 20114057.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    34. Predictors of health status in nondepressed and nondemented individuals with Parkinson's disease. Arch Clin Neuropsychol. 2009 Nov; 24(7):699-709. Schiehser DM, Han SD, Lessig S, Song DD, Zizak V, Filoteo JV. PMID: 19767296; PMCID: PMC2770862.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    35. Neuroimaging of semantic processing in schizophrenia: a parametric priming approach. Int J Psychophysiol. 2010 Feb; 75(2):100-6. Han SD, Wible CG. PMID: 19765623; PMCID: PMC2827622.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Development of set-shifting ability from late childhood through early adulthood. Arch Clin Neuropsychol. 2009 Sep; 24(6):565-74. Kalkut EL, Han SD, Lansing AE, Holdnack JA, Delis DC. PMID: 19679594.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    37. Clinical, cognitive, and genetic predictors of change in job status following traumatic brain injury in a military population. J Head Trauma Rehabil. 2009 Jan-Feb; 24(1):57-64. Han SD, Suzuki H, Drake AI, Jak AJ, Houston WS, Bondi MW. PMID: 19158597; PMCID: PMC3319716.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    38. Functional magnetic resonance imaging of compensatory neural recruitment in aging and risk for Alzheimer's disease: review and recommendations. Dement Geriatr Cogn Disord. 2009; 27(1):1-10. Han SD, Bangen KJ, Bondi MW. PMID: 19088472; PMCID: PMC2820574.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    39. Revision of the apolipoprotein E compensatory mechanism recruitment hypothesis. Alzheimers Dement. 2008 Jul; 4(4):251-4. Han SD, Bondi MW. PMID: 18631975.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    40. Apolipoprotein E and traumatic brain injury in a military population: evidence of a neuropsychological compensatory mechanism?. Journal of Neurology, Neurosurgery, and Psychiatry. 2007; 78(10):1103-1108. .
    41. Apolipoprotein E and traumatic brain injury in a military population: evidence of a neuropsychological compensatory mechanism? J Neurol Neurosurg Psychiatry. 2007 Oct; 78(10):1103-8. Han SD, Drake AI, Cessante LM, Jak AJ, Houston WS, Delis DC, Filoteo JV, Bondi MW. PMID: 17287237; PMCID: PMC2117544.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    42. Functional neuroimaging of word priming in males with chronic schizophrenia. Neuroimage. 2007 Mar; 35(1):273-82. Han SD, Nestor PG, Hale-Spencer M, Cohen A, Niznikiewicz M, McCarley RW, Wible CG. PMID: 17215145; PMCID: PMC1852450.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    43. Creativity Lost: The Importance of Testing Higher-Level Executive Functions in School-Age Children and Adolescents. Journal of Psychoeducational Assessment. 2007; 25:29-40. .
    44. Verbal paired-associate learning by APOE genotype in non-demented older adults: fMRI evidence of a right hemispheric compensatory response. Neurobiol Aging. 2007 Feb; 28(2):238-47. Han SD, Houston WS, Jak AJ, Eyler LT, Nagel BJ, Fleisher AS, Brown GG, Corey-Bloom J, Salmon DP, Thal LJ, Bondi MW. PMID: 16434125; PMCID: PMC1705815.
      View in: PubMed   Mentions: 74     Fields:    Translation:Humans
    45. Connectivity among semantic associates: an fMRI study of semantic priming. Brain Lang. 2006 Jun; 97(3):294-305. Wible CG, Han SD, Spencer MH, Kubicki M, Niznikiewicz MH, Jolesz FA, McCarley RW, Nestor P. PMID: 16413049.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    46. fMRI of lexical-semantic priming in a chronic schizophrenia patient. Appl Neuropsychol. 2006; 13(1):51-7. Han SD, Nestor PG, Wible CG. PMID: 16594871.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    47. Associative memory in chronic schizophrenia: a computational model. Schizophr Res. 2003 Jun 01; 61(2-3):255-63. Han SD, Nestor PG, Shenton ME, Niznikiewicz M, Hannah G, McCarley RW. PMID: 12729877; PMCID: PMC2849103.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    48. Semantic disturbance in schizophrenia and its relationship to the cognitive neuroscience of attention. Biol Psychol. 2001 Jul-Aug; 57(1-3):23-46. Nestor PG, Han SD, Niznikiewicz M, Salisbury D, Spencer K, Shenton ME, McCarley RW. PMID: 11454433; PMCID: PMC2849104.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
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