-
The MLL3/GRHL2 complex regulates malignant transformation and anti-tumor immunity in squamous cancer. J Exp Med. 2025 Apr 07; 222(4).
Nam C, Huang G, Zheng Y, Zhao H, Pan Y, Hu B, Wenger T, Van HT, Xu LY, Li EM, Koeffler HP, Ge K, Dou Y, Sinha UK, Park YM, Lin DC. PMID: 39964485; PMCID: PMC11834937.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Genetically Defined Organoid Models Reveal Mechanisms Driving Squamous Cell Neoplastic Evolution and Identify Potential Therapeutic Vulnerabilities. bioRxiv. 2025 Jan 22.
Zhao H, Park YM, Zheng Y, Mao Q, Collet C, Hu B, Zhou T, Lin L, Wong S, Pan Y, Monreal AV, Sinha UK, Sedghizadeh P, Soragni A, Lin DC. PMID: 39896470; PMCID: PMC11785044.
View in:
PubMed Mentions:
-
Comprehensive analysis of H3K27me3 LOCKs under different DNA methylation contexts reveal epigenetic redistribution in tumorigenesis. Epigenetics Chromatin. 2025 Jan 20; 18(1):6.
Liang Y, Liu M, Liu B, Ziman B, Peng G, Mao Q, Wang X, Jiang L, Lin DC, Zheng Y. PMID: 39833880; PMCID: PMC11748335.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Patient-derived tumor organoids to model drug response in gastric cancer. Cell Rep Med. 2024 Jul 16; 5(7):101650.
Vistoso Monreal A, Zhao H, Sedghizadeh PP, Lin DC. PMID: 39019014; PMCID: PMC11293348.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Genomic and single-cell characterization of patient-derived tumor organoid models of head and neck squamous cell carcinoma. bioRxiv. 2024 Jul 02.
Um JH, Zheng Y, Mao Q, Nam C, Zhao H, Koh YW, Shin SJ, Park YM, Lin DC. PMID: 39005427; PMCID: PMC11244938.
View in:
PubMed Mentions:
-
A druggable cascade links methionine metabolism to epigenomic reprogramming in squamous cell carcinoma. Proc Natl Acad Sci U S A. 2024 Jun 25; 121(26):e2320835121.
Nam C, Li LY, Yang Q, Ziman B, Zhao H, Hu B, Collet C, Jing P, Lei Q, Xu LY, Li EM, Koeffler HP, Sinha UK, Lin DC. PMID: 38900797; PMCID: PMC11214090.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
-
Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-γ signaling in squamous cancer. Nat Commun. 2024 Mar 20; 15(1):2484.
Jiang Y, Zheng Y, Zhang YW, Kong S, Dong J, Wang F, Ziman B, Gery S, Hao JJ, Zhou D, Zhou J, Ho AS, Sinha UK, Chen J, Zhang S, Yin C, Wei DD, Hazawa M, Pan H, Lu Z, Wei WQ, Wang MR, Koeffler HP, Lin DC, Jiang YY. PMID: 38509096; PMCID: PMC10954759.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
-
Epigenomic analyses identify FOXM1 as a key regulator of anti-tumor immune response in esophageal adenocarcinoma. Cell Death Dis. 2024 02 19; 15(2):152.
Ziman B, Yang Q, Zheng Y, Sheth M, Nam C, Zhao H, Zhang L, Hu B, Bhowmick NA, Sinha UK, Lin DC. PMID: 38373993; PMCID: PMC10876663.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
-
Establishing mouse and human oral esophageal organoids to investigate the tumor immune response. Dis Model Mech. 2024 Jan 01; 17(1).
Jiang Y, Zhao H, Kong S, Zhou D, Dong J, Cheng Y, Zhang S, Wang F, Kalra A, Yang N, Wei DD, Chen J, Zhang YW, Lin DC, Meltzer SJ, Jiang YY. PMID: 38258518; PMCID: PMC10846528.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
-
ARID1A Deficiency Regulates Anti-Tumor Immune Response in Esophageal Adenocarcinoma. Cancers (Basel). 2023 Nov 12; 15(22).
Zhang L, Zheng Y, Chien W, Ziman B, Billet S, Koeffler HP, Lin DC, Bhowmick NA. PMID: 38001638; PMCID: PMC10670331.
View in:
PubMed Mentions:
-
Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells. Cell Chem Biol. 2024 Apr 18; 31(4):792-804.e7.
Hazawa M, Ikliptikawati DK, Iwashima Y, Lin DC, Jiang Y, Qiu Y, Makiyama K, Matsumoto K, Kobayashi A, Nishide G, Keesiang L, Yoshino H, Minamoto T, Suzuki T, Kobayashi I, Meguro-Horike M, Jiang YY, Nishiuchi T, Konno H, Koeffler HP, Hosomichi K, Tajima A, Horike SI, Wong RW. PMID: 37924814.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics. Nat Commun. 2023 11 02; 14(1):7017.
Park YM, Lin DC. PMID: 37919364; PMCID: PMC10622517.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Comprehensive analyses of partially methylated domains and differentially methylated regions in esophageal cancer reveal both cell-type- and cancer-specific epigenetic regulation. Genome Biol. 2023 08 24; 24(1):193.
Zheng Y, Ziman B, Ho AS, Sinha UK, Xu LY, Li EM, Koeffler HP, Berman BP, Lin DC. PMID: 37620896; PMCID: PMC10463844.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Comparative impact of grade on mortality across salivary cancers: A novel, unifying staging system. Head Neck. 2023 08; 45(8):2028-2039.
Ho AS, Luu M, Balzer BL, Aro K, Jang JK, Mita AC, Scher KS, Mallen-St Clair J, Vasquez M, Bastien AJ, Epstein JB, Lin DC, Chen MM, Zumsteg ZS. PMID: 37345665.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Treatment for ovarian clear cell carcinoma with combined inhibition of WEE1 and ATR. J Ovarian Res. 2023 Apr 22; 16(1):80.
Chien W, Tyner JW, Gery S, Zheng Y, Li LY, Gopinatha Pillai MS, Nam C, Bhowmick NA, Lin DC, Koeffler HP. PMID: 37087441; PMCID: PMC10122390.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
A novel role of master regulator transcription factor in anti-tumor immunity and cancer immunotherapy. Theranostics. 2023; 13(6):1823-1825.
Sinha UK, Lin DC. PMID: 37064876; PMCID: PMC10091883.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Targeting RNA Exonuclease XRN1 Potentiates Efficacy of Cancer Immunotherapy. Cancer Res. 2023 03 15; 83(6):922-938.
Ran XB, Ding LW, Sun QY, Yang H, Said JW, Zhentang L, Madan V, Dakle P, Xiao JF, Loh X, Li Y, Xu L, Xiang XQ, Wang LZ, Goh BC, Lin DC, Chng WJ, Tan SY, Jha S, Koeffler HP. PMID: 36638333.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Large-scale genomic analyses reveal alterations and mechanisms underlying clonal evolution and immune evasion in esophageal cancer. Nat Commun. 2023 02 17; 14(1):893.
Lin DC. PMID: 36807265; PMCID: PMC9938131.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Single-cell genomics identifies immune response to neoadjuvant chemoradiotherapy. EBioMedicine. 2022 12; 86:104389.
Sinha UK, Kast WM, Lin DC. PMID: 36463779; PMCID: PMC9718959.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Generation and multiomic profiling of a TP53/CDKN2A double-knockout gastroesophageal junction organoid model. Sci Transl Med. 2022 11 30; 14(673):eabq6146.
Zhao H, Cheng Y, Kalra A, Ma K, Zheng Y, Ziman B, Tressler C, Glunde K, Shin EJ, Ngamruengphong S, Khashab M, Singh V, Anders RA, Jit S, Wyhs N, Chen W, Li X, Lin DC, Meltzer SJ. PMID: 36449602; PMCID: PMC10026384.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimals
-
Investigation of early neoplastic transformation and premalignant biology using genetically engineered organoid models. Comput Struct Biotechnol J. 2022; 20:5309-5315.
Zhao H, Collet C, Peng D, Sinha UK, Lin DC. PMID: 36212534; PMCID: PMC9513696.
View in:
PubMed Mentions:
4
-
Genomic and Epigenomic Characterization of Tumor Organoid Models. Cancers (Basel). 2022 Aug 24; 14(17).
Nam C, Ziman B, Sheth M, Zhao H, Lin DC. PMID: 36077628; PMCID: PMC9454968.
View in:
PubMed Mentions:
10
-
Quantitative Nodal Burden and Mortality Across Solid Cancers. J Natl Cancer Inst. 2022 07 11; 114(7):1003-1011.
Nguyen AT, Luu M, Nguyen VP, Lu DJ, Shiao SL, Kamrava M, Atkins KM, Mita AC, Scher KS, Spratt DE, Faries MB, Daskivich TJ, Lin DC, Chen MM, Clair JM, Sandler HM, Ho AS, Zumsteg ZS. PMID: 35311991; PMCID: PMC9275768.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Chemotherapy predictors and a time-dependent chemotherapy effect in metastatic esophageal cancer. World J Gastrointest Oncol. 2022 Feb 15; 14(2):511-524.
Midthun L, Kim S, Hendifar A, Osipov A, Klempner SJ, Chao J, Cho M, Guan M, Placencio-Hickok VR, Gangi A, Burch M, Lin DC, Waters K, Atkins K, Kamrava M, Gong J. PMID: 35317320; PMCID: PMC8919005.
View in:
PubMed Mentions:
2
-
Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment. Nat Commun. 2021 12 17; 12(1):7335.
Dinh HQ, Pan F, Wang G, Huang QF, Olingy CE, Wu ZY, Wang SH, Xu X, Xu XE, He JZ, Yang Q, Orsulic S, Haro M, Li LY, Huang GW, Breunig JJ, Koeffler HP, Hedrick CC, Xu LY, Lin DC, Li EM. PMID: 34921160; PMCID: PMC8683407.
View in:
PubMed Mentions:
101 Fields:
Translation:
HumansCells
-
Comparative Proteomic Analysis of HPV(+) Oropharyngeal Squamous Cell Carcinoma Recurrence. J Proteome Res. 2022 01 07; 21(1):200-208.
Ho AS, Robinson A, Shon W, Laury A, Raedschelders K, Venkatraman V, Holewinski R, Zhang Y, Shiao SL, Chen MM, Mallen-St Clair J, Lin DC, Zumsteg ZS, Van Eyk JE. PMID: 34846153.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Predicting master transcription factors from pan-cancer expression data. Sci Adv. 2021 Nov 26; 7(48):eabf6123.
Reddy J, Fonseca MAS, Corona RI, Nameki R, Segato Dezem F, Klein IA, Chang H, Chaves-Moreira D, Afeyan LK, Malta TM, Lin X, Abbasi F, Font-Tello A, Sabedot T, Cejas P, Rodríguez-Malavé N, Seo JH, Lin DC, Matulonis U, Karlan BY, Gayther SA, Pasaniuc B, Gusev A, Noushmehr H, Long H, Freedman ML, Drapkin R, Young RA, Abraham BJ, Lawrenson K. PMID: 34818047; PMCID: PMC8612691.
View in:
PubMed Mentions:
39 Fields:
-
Predictive Impact of Metastatic Lymph Node Burden on Distant Metastasis Across Papillary Thyroid Cancer Variants. Thyroid. 2021 10; 31(10):1549-1557.
Ho AS, Luu M, Shafqat I, Mallen-St Clair J, Chen MM, Chen Y, Jain M, Ali N, Patio C, Filarski CF, Lin DC, Bankston H, Braunstein GD, Sacks WL, Zumsteg ZS. PMID: 34470466.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
A closer look at esophageal cancer through different lenses. EBioMedicine. 2021 09; 71:103545.
Lin DC. PMID: 34419929; PMCID: PMC8385164.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Complete response to neoadjuvant pembrolizumab and capecitabine in microsatellite stable, Epstein-Barr virus-positive, locally advanced gastric adenocarcinoma: case report. AME Case Rep. 2021; 5:30.
Lin CY, Mehta P, Waters KM, Chang E, Hendifar A, Osipov A, Burch M, Lin DC, Gangi A, Cho M, Gong J. PMID: 34312609; PMCID: PMC8256116.
View in:
PubMed Mentions:
3
-
Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer. Nat Commun. 2021 07 16; 12(1):4362.
Li LY, Yang Q, Jiang YY, Yang W, Jiang Y, Li X, Hazawa M, Zhou B, Huang GW, Xu XE, Gery S, Zhang Y, Ding LW, Ho AS, Zumsteg ZS, Wang MR, Fullwood MJ, Freedland SJ, Meltzer SJ, Xu LY, Li EM, Koeffler HP, Lin DC. PMID: 34272396; PMCID: PMC8285542.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansCells
-
Publisher Correction: A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes. Nat Commun. 2021 Jun 28; 12(1):4106.
Zheng Y, Huang G, Silva TC, Yang Q, Jiang YY, Koeffler HP, Lin DC, Berman BP. PMID: 34183671; PMCID: PMC8238980.
View in:
PubMed Mentions: Fields:
-
Exercise impacts the epigenome of cancer. Prostate Cancer Prostatic Dis. 2022 09; 25(3):379-380.
Lin DC. PMID: 34045658.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Super-enhancer-mediated core regulatory circuitry in human cancer. Comput Struct Biotechnol J. 2021; 19:2790-2795.
Jiang Y, Jiang YY, Lin DC. PMID: 34093993; PMCID: PMC8138668.
View in:
PubMed Mentions:
17
-
A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes. Nat Commun. 2021 04 30; 12(1):2485.
Zheng Y, Huang G, Silva TC, Yang Q, Jiang YY, Koeffler HP, Lin DC, Berman BP. PMID: 33931649; PMCID: PMC8087678.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
-
Nodal staging convergence for HPV- and HPV+ oropharyngeal carcinoma. Cancer. 2021 05 15; 127(10):1590-1597.
Ho AS, Luu M, Kim S, Tighiouart M, Mita AC, Scher KS, Mallen-St Clair J, Walgama ES, Lin DC, Nguyen AT, Zumsteg ZS. PMID: 33595897.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Systematic Proteome and Lysine Succinylome Analysis Reveals Enhanced Cell Migration by Hyposuccinylation in Esophageal Squamous Cell Carcinoma. Mol Cell Proteomics. 2021; 20:100053.
Guo Z, Pan F, Peng L, Tian S, Jiao J, Liao L, Lu C, Zhai G, Wu Z, Dong H, Xu X, Wu J, Chen P, Bai X, Lin D, Xu L, Li E, Zhang K. PMID: 33561546; PMCID: PMC7970140.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
-
A Transcriptional Regulatory Loop of Master Regulator Transcription Factors, PPARG, and Fatty Acid Synthesis Promotes Esophageal Adenocarcinoma. Cancer Res. 2021 03 01; 81(5):1216-1229.
Ma S, Zhou B, Yang Q, Pan Y, Yang W, Freedland SJ, Ding LW, Freeman MR, Breunig JJ, Bhowmick NA, Pan J, Koeffler HP, Lin DC. PMID: 33402390; PMCID: PMC8026506.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
-
EWS-FLI1 regulates and cooperates with core regulatory circuitry in Ewing sarcoma. Nucleic Acids Res. 2020 11 18; 48(20):11434-11451.
Shi X, Zheng Y, Jiang L, Zhou B, Yang W, Li L, Ding L, Huang M, Gery S, Lin DC, Koeffler HP. PMID: 33080033; PMCID: PMC7672457.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
-
Prognostic Impact of Histologic Grade for Papillary Thyroid Carcinoma. Ann Surg Oncol. 2021 Mar; 28(3):1731-1739.
Ho AS, Luu M, Barrios L, Balzer BL, Bose S, Fan X, Walgama E, Mallen-St Clair J, Alam U, Shafqat I, Lin DC, Chen Y, Van Eyk JE, Maghami EG, Braunstein GD, Sacks WL, Zumsteg ZS. PMID: 32808161.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines. Gastroenterology. 2020 10; 159(4):1311-1327.e19.
Jiang YY, Jiang Y, Li CQ, Zhang Y, Dakle P, Kaur H, Deng JW, Lin RY, Han L, Xie JJ, Yan Y, Doan N, Zheng Y, Mayakonda A, Hazawa M, Xu L, Li Y, Aswad L, Jeitany M, Kanojia D, Guan XY, Said JW, Yang W, Fullwood MJ, Lin DC, Koeffler HP. PMID: 32619460.
View in:
PubMed Mentions:
103 Fields:
Translation:
HumansAnimalsCells
-
Characterization of super-enhancer-associated functional lncRNAs acting as ceRNAs in ESCC. Mol Oncol. 2020 09; 14(9):2203-2230.
Wang QY, Peng L, Chen Y, Liao LD, Chen JX, Li M, Li YY, Qian FC, Zhang YX, Wang F, Li CQ, Lin DC, Xu LY, Li EM. PMID: 32460441; PMCID: PMC7463357.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
-
Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade. Cell Rep. 2020 06 09; 31(10):107753.
Lin X, Dinglin X, Cao S, Zheng S, Wu C, Chen W, Li Q, Hu Q, Zheng F, Wu Z, Lin DC, Yao Y, Xu X, Xie Z, Liu Q, Yao H, Hu H. PMID: 32521278.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCells
-
Lineage-Specific Epigenomic and Genomic Activation of Oncogene HNF4A Promotes Gastrointestinal Adenocarcinomas. Cancer Res. 2020 07 01; 80(13):2722-2736.
Pan J, Silva TC, Gull N, Yang Q, Plummer JT, Chen S, Daigo K, Hamakubo T, Gery S, Ding LW, Jiang YY, Hu S, Xu LY, Li EM, Ding Y, Klempner SJ, Gayther SA, Berman BP, Koeffler HP, Lin DC. PMID: 32332020.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
-
dbInDel: a database of enhancer-associated insertion and deletion variants by analysis of H3K27ac ChIP-Seq. Bioinformatics. 2020 03 01; 36(5):1649-1651.
Huang M, Wang Y, Yang M, Yan J, Yang H, Zhuang W, Xu Y, Koeffler HP, Lin DC, Chen X. PMID: 31603498; PMCID: PMC7703781.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Identification of key genes by integrating DNA methylation and next-generation transcriptome sequencing for esophageal squamous cell carcinoma. Aging (Albany NY). 2020 01 21; 12(2):1332-1365.
Chen Y, Liao LD, Wu ZY, Yang Q, Guo JC, He JZ, Wang SH, Xu XE, Wu JY, Pan F, Lin DC, Xu LY, Li EM. PMID: 31962291; PMCID: PMC7053602.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
lncRNA CISAL Inhibits BRCA1 Transcription by Forming a Tertiary Structure at Its Promoter. iScience. 2020 Feb 21; 23(2):100835.
Fan S, Tian T, Lv X, Lei X, Yang Z, Liu M, Liang F, Li S, Lin X, Lin Z, Xie S, Li B, Chen W, Pan G, Lin X, Ou Z, Zhang Y, Peng Y, Xiao L, Zhang L, Sun S, Zhang H, Lin S, Li Q, Zeng B, Kontos F, Ruan Y, Ferrone S, Lin D, Tannous BA, Li J. PMID: 32000125; PMCID: PMC7033639.
View in:
PubMed Mentions:
16
-
EuRBPDB: a comprehensive resource for annotation, functional and oncological investigation of eukaryotic RNA binding proteins (RBPs). Nucleic Acids Res. 2020 01 08; 48(D1):D307-D313.
Liao JY, Yang B, Zhang YC, Wang XJ, Ye Y, Peng JW, Yang ZZ, He JH, Zhang Y, Hu K, Lin DC, Yin D. PMID: 31598693; PMCID: PMC6943034.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
-
Validation of a genomic classifier for prediction of metastasis and prostate cancer-specific mortality in African-American men following radical prostatectomy in an equal access healthcare setting. Prostate Cancer Prostatic Dis. 2020 09; 23(3):419-428.
Howard LE, Zhang J, Fishbane N, Hoedt AM, Klaassen Z, Spratt DE, Vidal AC, Lin D, Hitchins MP, You S, Freeman MR, Yamoah K, Davicioni E, Freedland SJ. PMID: 31844180.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Disease-specific alteration of karyopherin-α subtype establishes feed-forward oncogenic signaling in head and neck squamous cell carcinoma. Oncogene. 2020 03; 39(10):2212-2223.
Hazawa M, Sakai K, Kobayashi A, Yoshino H, Iga Y, Iwashima Y, Lim KS, Chih-Cheng Voon D, Jiang YY, Horike SI, Lin DC, Wong RW. PMID: 31822798; PMCID: PMC7056645.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
-
RNA-Binding Protein ZFP36L1 Suppresses Hypoxia and Cell-Cycle Signaling. Cancer Res. 2020 01 15; 80(2):219-233.
Loh XY, Sun QY, Ding LW, Mayakonda A, Venkatachalam N, Yeo MS, Silva TC, Xiao JF, Doan NB, Said JW, Ran XB, Zhou SQ, Dakle P, Shyamsunder P, Koh AP, Huang RY, Berman BP, Tan SY, Yang H, Lin DC, Koeffler HP. PMID: 31551365.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
-
Clonal Mutations Activate the NF-κB Pathway to Promote Recurrence of Nasopharyngeal Carcinoma. Cancer Res. 2019 Dec 01; 79(23):5930-5943.
You R, Liu YP, Lin DC, Li Q, Yu T, Zou X, Lin M, Zhang XL, He GP, Yang Q, Zhang YN, Xie YL, Jiang R, Wu CY, Zhang C, Cui C, Wang JQ, Wang Y, Zhuang AH, Guo GF, Hua YJ, Sun R, Yun JP, Zuo ZX, Liu ZX, Zhu XF, Kang TB, Qian CN, Mai HQ, Sun Y, Zeng MS, Feng L, Zeng YX, Chen MY. PMID: 31484669.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
-
Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in oesophageal adenocarcinoma. Gut. 2020 04; 69(4):630-640.
Chen L, Huang M, Plummer J, Pan J, Jiang YY, Yang Q, Silva TC, Gull N, Chen S, Ding LW, An O, Yang H, Cheng Y, Said JW, Doan N, Dinjens WN, Waters KM, Tuli R, Gayther SA, Klempner SJ, Berman BP, Meltzer SJ, Lin DC, Koeffler HP. PMID: 31409603; PMCID: PMC8108390.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansCells
-
Biological Significance of Tumor Heterogeneity in Esophageal Squamous Cell Carcinoma. Cancers (Basel). 2019 Aug 12; 11(8).
Lin L, Lin DC. PMID: 31409002; PMCID: PMC6721624.
View in:
PubMed Mentions:
27
-
SOX7 regulates MAPK/ERK-BIM mediated apoptosis in cancer cells. Oncogene. 2019 08; 38(34):6196-6210.
Sun QY, Ding LW, Johnson K, Zhou S, Tyner JW, Yang H, Doan NB, Said JW, Xiao JF, Loh XY, Ran XB, Venkatachalam N, Lao Z, Chen Y, Xu L, Fan LF, Chien W, Lin DC, Koeffler HP. PMID: 31332289.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
-
SEanalysis: a web tool for super-enhancer associated regulatory analysis. Nucleic Acids Res. 2019 07 02; 47(W1):W248-W255.
Qian FC, Li XC, Guo JC, Zhao JM, Li YY, Tang ZD, Zhou LW, Zhang J, Bai XF, Jiang Y, Pan Q, Wang QY, Li EM, Li CQ, Xu LY, Lin DC. PMID: 31028388; PMCID: PMC6602466.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
-
ELMER v.2: an R/Bioconductor package to reconstruct gene regulatory networks from DNA methylation and transcriptome profiles. Bioinformatics. 2019 06 01; 35(11):1974-1977.
Silva TC, Coetzee SG, Gull N, Yao L, Hazelett DJ, Noushmehr H, Lin DC, Berman BP. PMID: 30364927; PMCID: PMC6546131.
View in:
PubMed Mentions:
69 Fields:
Translation:
Cells
-
LNK suppresses interferon signaling in melanoma. Nat Commun. 2019 05 20; 10(1):2230.
Ding LW, Sun QY, Edwards JJ, Fernández LT, Ran XB, Zhou SQ, Scolyer RA, Wilmott JS, Thompson JF, Doan N, Said JW, Venkatachalam N, Xiao JF, Loh XY, Pein M, Xu L, Mullins DW, Yang H, Lin DC, Koeffler HP. PMID: 31110180; PMCID: PMC6527565.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
-
Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells. Nat Cell Biol. 2019 04; 21(4):498-510.
Chen F, Chen J, Yang L, Liu J, Zhang X, Zhang Y, Tu Q, Yin D, Lin D, Wong PP, Huang D, Xing Y, Zhao J, Li M, Liu Q, Su F, Su S, Song E. PMID: 30936474.
View in:
PubMed Mentions:
398 Fields:
Translation:
HumansCells
-
Super-enhancer-associated MEIS1 promotes transcriptional dysregulation in Ewing sarcoma in co-operation with EWS-FLI1. Nucleic Acids Res. 2019 02 20; 47(3):1255-1267.
Lin L, Huang M, Shi X, Mayakonda A, Hu K, Jiang YY, Guo X, Chen L, Pang B, Doan N, Said JW, Xie J, Gery S, Cheng X, Lin Z, Li J, Berman BP, Yin D, Lin DC, Koeffler HP. PMID: 30496486; PMCID: PMC6379679.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansCells
-
Mutational and transcriptomic profiling of acute leukemia of ambiguous lineage reveals obscure but clinically important lineage bias. Haematologica. 2019 05; 104(5):e200-e203.
Lao ZT, Ding LW, An O, Hattori N, Sun QY, Tan KT, Mayakonda A, Chuan WG, Madan V, Lin DC, Yang H, Koeffler HP. PMID: 30514800; PMCID: PMC6518916.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Super-Enhancer-Associated Long Noncoding RNA HCCL5 Is Activated by ZEB1 and Promotes the Malignancy of Hepatocellular Carcinoma. Cancer Res. 2019 02 01; 79(3):572-584.
Peng L, Jiang B, Yuan X, Qiu Y, Peng J, Huang Y, Zhang C, Zhang Y, Lin Z, Li J, Yao W, Deng W, Zhang Y, Meng M, Pan X, Li C, Yin D, Bi X, Li G, Lin DC. PMID: 30482773.
View in:
PubMed Mentions:
86 Fields:
Translation:
HumansAnimalsCells
-
Maftools: efficient and comprehensive analysis of somatic variants in cancer. Genome Res. 2018 11; 28(11):1747-1756.
Mayakonda A, Lin DC, Assenov Y, Plass C, Koeffler HP. PMID: 30341162; PMCID: PMC6211645.
View in:
PubMed Mentions:
2797 Fields:
Translation:
Humans
-
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines. BMC Cancer. 2018 Oct 01; 18(1):940.
Tan KT, Ding LW, Sun QY, Lao ZT, Chien W, Ren X, Xiao JF, Loh XY, Xu L, Lill M, Mayakonda A, Lin DC, Yang H, Koeffler HP. PMID: 30285677; PMCID: PMC6167786.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Co-activation of super-enhancer-driven CCAT1 by TP63 and SOX2 promotes squamous cancer progression. Nat Commun. 2018 09 06; 9(1):3619.
Jiang Y, Jiang YY, Xie JJ, Mayakonda A, Hazawa M, Chen L, Xiao JF, Li CQ, Huang ML, Ding LW, Sun QY, Xu L, Kanojia D, Jeitany M, Deng JW, Liao LD, Soukiasian HJ, Berman BP, Hao JJ, Xu LY, Li EM, Wang MR, Bi XG, Lin DC, Koeffler HP. PMID: 30190462; PMCID: PMC6127298.
View in:
PubMed Mentions:
130 Fields:
Translation:
HumansAnimalsCells
-
Modeling Wnt signaling by CRISPR-Cas9 genome editing recapitulates neoplasia in human Barrett epithelial organoids. Cancer Lett. 2018 11 01; 436:109-118.
Liu X, Cheng Y, Abraham JM, Wang Z, Wang Z, Ke X, Yan R, Shin EJ, Ngamruengphong S, Khashab MA, Zhang G, McNamara G, Ewald AJ, Lin D, Liu Z, Meltzer SJ. PMID: 30144514; PMCID: PMC6152930.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
-
The c-MYC-BMI1 axis is essential for SETDB1-mediated breast tumourigenesis. J Pathol. 2018 09; 246(1):89-102.
Xiao JF, Sun QY, Ding LW, Chien W, Liu XY, Mayakonda A, Jiang YY, Loh XY, Ran XB, Doan NB, Castor B, Chia D, Said JW, Tan KT, Yang H, Fu XY, Lin DC, Koeffler HP. PMID: 29926931.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
-
ARID1A and CEBPα cooperatively inhibit UCA1 transcription in breast cancer. Oncogene. 2018 11; 37(45):5939-5951.
Guo X, Zhang Y, Mayakonda A, Madan V, Ding LW, Lin LH, Zia S, Gery S, Tyner JW, Zhou W, Yin D, Lin DC, Koeffler HP. PMID: 29980791.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
-
Clonality and clonal evolution analysis of paediatric ALL based on B-cell receptor/T-cell receptor rearrangement. Br J Haematol. 2019 03; 184(5):829-833.
Ding LW, Tan KT, Sun QY, Lao ZT, Yang H, Jiang N, Chien W, Xiao JF, Loh XY, Huang ML, Lill M, Lin DC, Yeoh AEJ, Koeffler HP. PMID: 29532914.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Super-Enhancer-Driven Long Non-Coding RNA LINC01503, Regulated by TP63, Is Over-Expressed and Oncogenic in Squamous Cell Carcinoma. Gastroenterology. 2018 06; 154(8):2137-2151.e1.
Xie JJ, Jiang YY, Jiang Y, Li CQ, Lim MC, An O, Mayakonda A, Ding LW, Long L, Sun C, Lin LH, Chen L, Wu JY, Wu ZY, Cao Q, Fang WK, Yang W, Soukiasian H, Meltzer SJ, Yang H, Fullwood M, Xu LY, Li EM, Lin DC, Koeffler HP. PMID: 29454790.
View in:
PubMed Mentions:
135 Fields:
Translation:
HumansAnimalsCells
-
SLC52A3 expression is activated by NF-κB p65/Rel-B and serves as a prognostic biomarker in esophageal cancer. Cell Mol Life Sci. 2018 07; 75(14):2643-2661.
Long L, Pang XX, Lei F, Zhang JS, Wang W, Liao LD, Xu XE, He JZ, Wu JY, Wu ZY, Wang LD, Lin DC, Li EM, Xu LY. PMID: 29428966; PMCID: PMC6003972.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
-
Non-malignant epithelial cells preferentially proliferate from nasopharyngeal carcinoma biopsy cultured under conditionally reprogrammed conditions. Sci Rep. 2017 12 12; 7(1):17359.
Yu F, Lu Y, Tao L, Jiang YY, Lin DC, Wang L, Petersson F, Yoshiyama H, Koeffler PH, Goh BC, Loh KS. PMID: 29234119; PMCID: PMC5727117.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
-
ROCK-dependent phosphorylation of NUP62 regulates p63 nuclear transport and squamous cell carcinoma proliferation. EMBO Rep. 2018 01; 19(1):73-88.
Hazawa M, Lin DC, Kobayashi A, Jiang YY, Xu L, Dewi FRP, Mohamed MS, Nakada M, Meguro-Horike M, Horike SI, Koeffler HP, Wong RW. PMID: 29217659; PMCID: PMC5757218.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCells
-
Circadian clock cryptochrome proteins regulate autoimmunity. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):12548-12553.
Cao Q, Zhao X, Bai J, Gery S, Sun H, Lin DC, Chen Q, Chen Z, Mack L, Yang H, Deng R, Shi X, Chong LW, Cho H, Xie J, Li QZ, Müschen M, Atkins AR, Liddle C, Yu RT, Alkan S, Said JW, Zheng Y, Downes M, Evans RM, Koeffler HP. PMID: 29109286; PMCID: PMC5703267.
View in:
PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
-
Genomic lesions drive the metastasis of esophageal squamous cell carcinoma. J Thorac Dis. 2017 Oct; 9(10):3523-3524.
Lin DC, Koeffler HP. PMID: 29268331; PMCID: PMC5723768.
View in:
PubMed Mentions:
2
-
Degalactotigonin, a Natural Compound from Solanum nigrum L., Inhibits Growth and Metastasis of Osteosarcoma through GSK3β Inactivation-Mediated Repression of the Hedgehog/Gli1 Pathway. Clin Cancer Res. 2018 01 01; 24(1):130-144.
Zhao Z, Jia Q, Wu MS, Xie X, Wang Y, Song G, Zou CY, Tang Q, Lu J, Huang G, Wang J, Lin DC, Koeffler HP, Yin JQ, Shen J. PMID: 28951519.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
-
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma. Cancer Res. 2017 12 01; 77(23):6614-6626.
Yuan J, Jiang YY, Mayakonda A, Huang M, Ding LW, Lin H, Yu F, Lu Y, Loh TKS, Chow M, Savage S, Tyner JW, Lin DC, Koeffler HP. PMID: 28951465; PMCID: PMC6637769.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansAnimalsCells
-
Correction: Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia. Oncotarget. 2017 Sep 08; 8(38):64651.
Sun H, Lin DC, Guo X, Masouleh BK, Gery S, Cao Q, Alkan S, Ikezoe T, Akiba C, Paquette R, Chien W, Müller-Tidow C, Jing Y, Agelopoulos K, Müschen M, Koeffler HP. PMID: 28969101; PMCID: PMC5610033.
View in:
PubMed Mentions:
1 Fields:
-
Identification of distinct mutational patterns and new driver genes in oesophageal squamous cell carcinomas and adenocarcinomas. Gut. 2018 10; 67(10):1769-1779.
Lin DC, Dinh HQ, Xie JJ, Mayakonda A, Silva TC, Jiang YY, Ding LW, He JZ, Xu XE, Hao JJ, Wang MR, Li C, Xu LY, Li EM, Berman BP, Phillip Koeffler H. PMID: 28860350; PMCID: PMC5980794.
View in:
PubMed Mentions:
70 Fields:
Translation:
HumansAnimalsCells
-
Valosin-Containing Protein/p97 as a Novel Therapeutic Target in Acute Lymphoblastic Leukemia. Neoplasia. 2017 Oct; 19(10):750-761.
Gugliotta G, Sudo M, Cao Q, Lin DC, Sun H, Takao S, Le Moigne R, Rolfe M, Gery S, Müschen M, Cavo M, Koeffler HP. PMID: 28843399; PMCID: PMC5576979.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
Genomic and Epigenomic Aberrations in Esophageal Squamous Cell Carcinoma and Implications for Patients. Gastroenterology. 2018 01; 154(2):374-389.
Lin DC, Wang MR, Koeffler HP. PMID: 28757263; PMCID: PMC5951382.
View in:
PubMed Mentions:
133 Fields:
Translation:
HumansCells
-
BCL6 promotes glioma and serves as a therapeutic target. Proc Natl Acad Sci U S A. 2017 04 11; 114(15):3981-3986.
Xu L, Chen Y, Dutra-Clarke M, Mayakonda A, Hazawa M, Savinoff SE, Doan N, Said JW, Yong WH, Watkins A, Yang H, Ding LW, Jiang YY, Tyner JW, Ching J, Kovalik JP, Madan V, Chan SL, Müschen M, Breunig JJ, Lin DC, Koeffler HP. PMID: 28356518; PMCID: PMC5393201.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
-
Identification of a Novel SYK/c-MYC/MALAT1 Signaling Pathway and Its Potential Therapeutic Value in Ewing Sarcoma. Clin Cancer Res. 2017 Aug 01; 23(15):4376-4387.
Sun H, Lin DC, Cao Q, Pang B, Gae DD, Lee VKM, Lim HJ, Doan N, Said JW, Gery S, Chow M, Mayakonda A, Forscher C, Tyner JW, Koeffler HP. PMID: 28336564.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
-
Mutational profiling of acute lymphoblastic leukemia with testicular relapse. J Hematol Oncol. 2017 03 02; 10(1):65.
Ding LW, Sun QY, Mayakonda A, Tan KT, Chien W, Lin DC, Jiang YY, Xu L, Garg M, Lao ZT, Lill M, Yang H, Yeoh AE, Koeffler HP. PMID: 28253933; PMCID: PMC5335697.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Genomic and Epigenomic Heterogeneity of Hepatocellular Carcinoma. Cancer Res. 2017 05 01; 77(9):2255-2265.
Lin DC, Mayakonda A, Dinh HQ, Huang P, Lin L, Liu X, Ding LW, Wang J, Berman BP, Song EW, Yin D, Koeffler HP. PMID: 28302680; PMCID: PMC5413372.
View in:
PubMed Mentions:
110 Fields:
Translation:
Humans
-
Copy number analysis identifies tumor suppressive lncRNAs in human osteosarcoma. Int J Oncol. 2017 Mar; 50(3):863-872.
Xie J, Lin D, Lee DH, Akunowicz J, Hansen M, Miller C, Sanada M, Kato M, Akagi T, Kawamata N, Ogawa S, Koeffler HP. PMID: 28197627.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia. Cancer Res. 2017 01 15; 77(2):390-400.
Ding LW, Sun QY, Tan KT, Chien W, Mayakonda A, Yeoh AEJ, Kawamata N, Nagata Y, Xiao JF, Loh XY, Lin DC, Garg M, Jiang YY, Xu L, Lim SL, Liu LZ, Madan V, Sanada M, Fernández LT, Hema Preethi SS, Lill M, Kantarjian HM, Kornblau SM, Miyano S, Liang DC, Ogawa S, Shih LY, Yang H, Koeffler HP. PMID: 27872090; PMCID: PMC5243866.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansAnimals
-
Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma. Nat Genet. 2016 12; 48(12):1500-1507.
Hao JJ, Lin DC, Dinh HQ, Mayakonda A, Jiang YY, Chang C, Jiang Y, Lu CC, Shi ZZ, Xu X, Zhang Y, Cai Y, Wang JW, Zhan QM, Wei WQ, Berman BP, Wang MR, Koeffler HP. PMID: 27749841; PMCID: PMC5127772.
View in:
PubMed Mentions:
151 Fields:
Translation:
HumansCells
-
Targeting super-enhancer-associated oncogenes in oesophageal squamous cell carcinoma. Gut. 2017 08; 66(8):1358-1368.
Jiang YY, Lin DC, Mayakonda A, Hazawa M, Ding LW, Chien WW, Xu L, Chen Y, Xiao JF, Senapedis W, Baloglu E, Kanojia D, Shang L, Xu X, Yang H, Tyner JW, Wang MR, Koeffler HP. PMID: 27196599; PMCID: PMC5912916.
View in:
PubMed Mentions:
134 Fields:
Translation:
HumansAnimalsCells
-
Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia. Oncotarget. 2016 Apr 05; 7(14):18736-49.
Sun H, Lin DC, Guo X, Kharabi Masouleh B, Gery S, Cao Q, Alkan S, Ikezoe T, Akiba C, Paquette R, Chien W, Müller-Tidow C, Jing Y, Agelopoulos K, Müschen M, Koeffler HP. PMID: 26934650; PMCID: PMC4951325.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
-
CRM1 Inhibition Promotes Cytotoxicity in Ewing Sarcoma Cells by Repressing EWS-FLI1-Dependent IGF-1 Signaling. Cancer Res. 2016 05 01; 76(9):2687-97.
Sun H, Lin DC, Cao Q, Guo X, Marijon H, Zhao Z, Gery S, Xu L, Yang H, Pang B, Lee VK, Lim HJ, Doan N, Said JW, Chu P, Mayakonda A, Thomas T, Forscher C, Baloglu E, Shacham S, Rajalingam R, Koeffler HP. PMID: 26956669.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
-
Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse. Blood. 2015 Nov 26; 126(22):2491-501.
Garg M, Nagata Y, Kanojia D, Mayakonda A, Yoshida K, Haridas Keloth S, Zang ZJ, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ding LW, Alpermann T, Sun QY, Lin DC, Chien W, Madan V, Liu LZ, Tan KT, Sampath A, Venkatesan S, Inokuchi K, Wakita S, Yamaguchi H, Chng WJ, Kham SK, Yeoh AE, Sanada M, Schiller J, Kreuzer KA, Kornblau SM, Kantarjian HM, Haferlach T, Lill M, Kuo MC, Shih LY, Blau IW, Blau O, Yang H, Ogawa S, Koeffler HP. PMID: 26438511; PMCID: PMC4661172.
View in:
PubMed Mentions:
129 Fields:
Translation:
HumansCells
-
Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma. Cancer Res. 2015 May 01; 75(9):1815-27.
Lin DC, Xu L, Chen Y, Yan H, Hazawa M, Doan N, Said JW, Ding LW, Liu LZ, Yang H, Yu S, Kahn M, Yin D, Koeffler HP. PMID: 25877876; PMCID: PMC4417379.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
-
Expression of CCN family members correlates with the clinical features of hepatocellular carcinoma. Oncol Rep. 2015 Mar; 33(3):1481-92.
Zhang H, Li W, Huang P, Lin L, Ye H, Lin D, Koeffler HP, Wang J, Yin D. PMID: 25571929.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
SETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway. J Pathol. 2015 Mar; 235(4):559-70.
Sun QY, Ding LW, Xiao JF, Chien W, Lim SL, Hattori N, Goodglick L, Chia D, Mah V, Alavi M, Kim SR, Doan NB, Said JW, Loh XY, Xu L, Liu LZ, Yang H, Hayano T, Shi S, Xie D, Lin DC, Koeffler HP. PMID: 25404354; PMCID: PMC4333197.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
-
The genomic landscape of nasopharyngeal carcinoma. Nat Genet. 2014 Aug; 46(8):866-71.
Lin DC, Meng X, Hazawa M, Nagata Y, Varela AM, Xu L, Sato Y, Liu LZ, Ding LW, Sharma A, Goh BC, Lee SC, Petersson BF, Yu FG, Macary P, Oo MZ, Ha CS, Yang H, Ogawa S, Loh KS, Koeffler HP. PMID: 24952746.
View in:
PubMed Mentions:
198 Fields:
Translation:
HumansAnimalsCells
-
Oncogenic function and prognostic significance of protein tyrosine phosphatase PRL-1 in hepatocellular carcinoma. Oncotarget. 2014 Jun 15; 5(11):3685-96.
Jin S, Wang K, Xu K, Xu J, Sun J, Chu Z, Lin D, Koeffler PH, Wang J, Yin D. PMID: 25003523; PMCID: PMC4116513.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
-
Targeting genetic lesions in esophageal cancer. Cell Cycle. 2014; 13(13):2013-4.
Lin DC, Wang MR, Koeffler HP. PMID: 24901941; PMCID: PMC4111687.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
Genomic and molecular characterization of esophageal squamous cell carcinoma. Nat Genet. 2014 May; 46(5):467-73.
Lin DC, Hao JJ, Nagata Y, Xu L, Shang L, Meng X, Sato Y, Okuno Y, Varela AM, Ding LW, Garg M, Liu LZ, Yang H, Yin D, Shi ZZ, Jiang YY, Gu WY, Gong T, Zhang Y, Xu X, Kalid O, Shacham S, Ogawa S, Wang MR, Koeffler HP. PMID: 24686850; PMCID: PMC4070589.
View in:
PubMed Mentions:
363 Fields:
Translation:
HumansAnimalsCells
-
An emerging role of PARK2 in cancer. J Mol Med (Berl). 2014 Jan; 92(1):31-42.
Xu L, Lin DC, Yin D, Koeffler HP. PMID: 24297497.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
-
Consistent and differential genetic aberrations between esophageal dysplasia and squamous cell carcinoma detected by array comparative genomic hybridization. Clin Cancer Res. 2013 Nov 01; 19(21):5867-78.
Shi ZZ, Shang L, Jiang YY, Hao JJ, Zhang Y, Zhang TT, Lin DC, Liu SG, Wang BS, Gong T, Zhan QM, Wang MR. PMID: 24009147.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansCells
-
SH2B3 (LNK) mutations from myeloproliferative neoplasms patients have mild loss of function against wild type JAK2 and JAK2 V617F. Br J Haematol. 2013 Jun; 161(6):811-20.
Koren-Michowitz M, Gery S, Tabayashi T, Lin D, Alvarez R, Nagler A, Koeffler HP. PMID: 23590807; PMCID: PMC3672250.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
-
Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers. Proc Natl Acad Sci U S A. 2013 Apr 09; 110(15):6109-14.
Lin DC, Xu L, Ding LW, Sharma A, Liu LZ, Yang H, Tan P, Vadgama J, Karlan BY, Lester J, Urban N, Schummer M, Doan N, Said JW, Sun H, Walsh M, Thomas CJ, Patel P, Yin D, Chan D, Koeffler HP. PMID: 23536305; PMCID: PMC3625360.
View in:
PubMed Mentions:
40 Fields:
Translation:
HumansCells
-
Adaptor protein Lnk binds to and inhibits normal and leukemic FLT3. Blood. 2012 Oct 18; 120(16):3310-7.
Lin DC, Yin T, Koren-Michowitz M, Ding LW, Gueller S, Gery S, Tabayashi T, Bergholz U, Kazi JU, Rönnstrand L, Stocking C, Koeffler HP. PMID: 22942183; PMCID: PMC3476541.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
Reciprocal activation between PLK1 and Stat3 contributes to survival and proliferation of esophageal cancer cells. Gastroenterology. 2012 Mar; 142(3):521-530.e3.
Zhang Y, Du XL, Wang CJ, Lin DC, Ruan X, Feng YB, Huo YQ, Peng H, Cui JL, Zhang TT, Wang YQ, Zhang H, Zhan QM, Wang MR. PMID: 22108192.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
-
PLK1 Is transcriptionally activated by NF-κB during cell detachment and enhances anoikis resistance through inhibiting β-catenin degradation in esophageal squamous cell carcinoma. Clin Cancer Res. 2011 Jul 01; 17(13):4285-95.
Lin DC, Zhang Y, Pan QJ, Yang H, Shi ZZ, Xie ZH, Wang BS, Hao JJ, Zhang TT, Xu X, Zhan QM, Wang MR. PMID: 21610149.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
-
Genomic alterations with impact on survival in esophageal squamous cell carcinoma identified by array comparative genomic hybridization. Genes Chromosomes Cancer. 2011 Jul; 50(7):518-26.
Shi ZZ, Liang JW, Zhan T, Wang BS, Lin DC, Liu SG, Hao JJ, Yang H, Zhang Y, Zhan QM, Zhang KT, Wang MR. PMID: 21484929.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
Atypical protein kinase Cι (PKCι) promotes metastasis of esophageal squamous cell carcinoma by enhancing resistance to Anoikis via PKCι-SKP2-AKT pathway. Mol Cancer Res. 2011 Apr; 9(4):390-402.
Liu SG, Wang BS, Jiang YY, Zhang TT, Shi ZZ, Yang Y, Yang YL, Wang XC, Lin DC, Zhang Y, Yang H, Cai Y, Zhan QM, Wang MR. PMID: 21310827.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
-
[Expression of cell cycle related proteins cyclin D1, p53 and p21WAF1/Cip1 in esophageal squamous cell carcinoma]. Yi Chuan. 2010 May; 32(5):455-60.
Lin DC, Shi ZZ, Xue LY, Chen W, Xu X, Han YL, Lv N, Wang MR. PMID: 20466633.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Suppression of anoikis by SKP2 amplification and overexpression promotes metastasis of esophageal squamous cell carcinoma. Mol Cancer Res. 2009 Jan; 7(1):12-22.
Wang XC, Wu YP, Ye B, Lin DC, Feng YB, Zhang ZQ, Xu X, Han YL, Cai Y, Dong JT, Zhan QM, Wu M, Wang MR. PMID: 19147533.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells