Brian Spencer

Title(s)Assistant Professor Of Research Physiology and Neuroscience
SchoolKeck School of Medicine of Usc
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Systemic delivery of anti-sense oligonucleotide targeting α-synuclein for treatment in a mouse model of multiple system atrophy. Front Aging Neurosci. 2026; 18:1807721. Spencer B, Quach B, Salehi S, Rissman RA. PMID: 42137641; PMCID: PMC13168115.
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    2. Peptide-mediated delivery of an α-synuclein-targeting antisense oligonucleotide: Pharmacokinetics, safety, and central nervous system efficacy in a synucleinopathy model. Drug Metab Dispos. 2026 06; 54(6):100304. Ahammad RU, Quach B, Salehi S, Rissman RA, Spencer B. PMID: 42172871.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    3. Systemic delivery of anti-sense oligonucleotide targeting a-synuclein for the treatment of multiple system atrophy. Res Sq. 2025 Nov 07. Spencer B, Quach B, Salehi S, Rissman RA. PMID: 41282154; PMCID: PMC12637822.
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    4. A splice-switching antisense oligonucleotide targeting APP reduces accumulation of α-synuclein in a mouse model of Parkinson's disease. Alzheimers Dement (N Y). 2025 Apr-Jun; 11(2):e70117. Ahammad RU, Spencer B, Quach B, Salehi S, Rissman RA. PMID: 40556661; PMCID: PMC12185244.
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    5. Differential roles of human tau isoforms in the modulation of inflammation and development of neuropathology. Neurobiol Dis. 2025 07; 211:106942. Spencer B, Schueler A, Sung D, Rissman RA. PMID: 40348205; PMCID: PMC12178306.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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