Yao Wei Lu, PhD

Title(s)Assistant Professor of Medicine
SchoolKeck School of Medicine of Usc
ORCID ORCID Icon0000-0001-6200-2974 Additional info
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    2023American Heart Association (AHA) Second Century Early Faculty Independence Award

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Senescent Cell Depletion Alleviates Obesity-related Metabolic and Cardiac Disorders. Mol Metab. 2024 Nov 16; 102065. de Oliveira Silva T, Lunardon G, Lino CA, de Almeida Silva A, Zhang S, Irigoyen MCC, Lu YW, Mably JD, Barreto-Chaves MLM, Wang DZ, Diniz GP. PMID: 39557194.
      View in: PubMed   Mentions:    Fields:    
    2. Therapeutic Inhibition of LincRNA-p21 Protects Against Cardiac Hypertrophy. Circ Res. 2024 Jul 19; 135(3):434-449. Wang Y, Zhang M, Wang R, Lin J, Ma Q, Guo H, Huang H, Liang Z, Cao Y, Zhang X, Lu YW, Liu J, Xiao F, Yan H, Dimitrova N, Huang ZP, Mably JD, Pu WT, Wang DZ. PMID: 38864216; PMCID: PMC11257812.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. The long noncoding RNA CARDINAL attenuates cardiac hypertrophy by modulating protein translation. J Clin Invest. 2024 May 14; 134(13). He X, Yang T, Lu YW, Wu G, Dai G, Ma Q, Zhang M, Zhou H, Long T, Yan Y, Liang Z, Liu C, Pu WT, Dong Y, Ou J, Chen H, Mably JD, He J, Wang DZ, Huang ZP. PMID: 38743498; PMCID: PMC11213465.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. Reduced Mitochondrial Protein Translation Promotes Cardiomyocyte Proliferation and Heart Regeneration. Circulation. 2023 12 05; 148(23):1887-1906. Gao F, Liang T, Lu YW, Pu L, Fu X, Dong X, Hong T, Zhang F, Liu N, Zhou Y, Wang H, Liang P, Guo Y, Yu H, Zhu W, Hu X, Chen H, Zhou B, Pu WT, Mably JD, Wang J, Wang DZ, Chen J. PMID: 37905452; PMCID: PMC10841688.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    5. PCBP1 regulates alternative splicing of AARS2 in congenital cardiomyopathy. bioRxiv. 2023 May 18. Lu YW, Liang Z, Guo H, Fernandes T, Espinoza-Lewis RA, Wang T, Li K, Li X, Singh GB, Wang Y, Cowan D, Mably JD, Philpott CC, Chen H, Wang DZ. PMID: 37293078; PMCID: PMC10245752.
      View in: PubMed   Mentions:
    6. INKILN is a Novel Long Noncoding RNA Promoting Vascular Smooth Muscle Inflammation via Scaffolding MKL1 and USP10. Circulation. 2023 07 04; 148(1):47-67. Zhang W, Zhao J, Deng L, Ishimwe N, Pauli J, Wu W, Shan S, Kempf W, Ballantyne MD, Kim D, Lyu Q, Bennett M, Rodor J, Turner AW, Lu YW, Gao P, Choi M, Warthi G, Kim HW, Barroso MM, Bryant WB, Miller CL, Weintraub NL, Maegdefessel L, Miano JM, Baker AH, Long X. PMID: 37199168; PMCID: PMC10330325.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    7. A defect in mitochondrial protein translation influences mitonuclear communication in the heart. Nat Commun. 2023 03 22; 14(1):1595. Gao F, Liang T, Lu YW, Fu X, Dong X, Pu L, Hong T, Zhou Y, Zhang Y, Liu N, Zhang F, Liu J, Malizia AP, Yu H, Zhu W, Cowan DB, Chen H, Hu X, Mably JD, Wang J, Wang DZ, Chen J. PMID: 36949106; PMCID: PMC10033703.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    8. Ryanodine receptor 2 (RYR2) dysfunction activates the unfolded protein response and perturbs cardiomyocyte maturation. Cardiovasc Res. 2023 03 17; 119(1):221-235. Guo Y, Cao Y, Jardin BD, Zhang X, Zhou P, Guatimosim S, Lin J, Chen Z, Zhang Y, Mazumdar N, Lu F, Ma Q, Lu YW, Zhao M, Wang DZ, Dong E, Pu WT. PMID: 35576474; PMCID: PMC10233305.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    9. mt-Ty 5'tiRNA regulates skeletal muscle cell proliferation and differentiation. Cell Prolif. 2023 Aug; 56(8):e13416. Cao J, Wang X, Advani V, Lu YW, Malizia AP, Singh GB, Huang ZP, Liu J, Wang C, Oliveira EM, Mably JD, Chen K, Wang DZ. PMID: 36756712; PMCID: PMC10392060.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    10. INKILN is a novel long noncoding RNA promoting vascular smooth muscle inflammation via scaffolding MKL1 and USP10. bioRxiv. 2023 Jan 09. Zhang W, Zhao J, Deng L, Ishimwe N, Pauli J, Wu W, Shan S, Kempf W, Ballantyne MD, Kim D, Lyu Q, Bennett M, Rodor J, Turner AW, Lu YW, Gao P, Choi M, Warthi G, Kim HW, Barroso MM, Bryant WB, Miller CL, Weintraub NL, Maegdefessel L, Miano JM, Baker AH, Long X. PMID: 36711681; PMCID: PMC9881896.
      View in: PubMed   Mentions:
    11. Sox17 mediates adult arterial endothelial cell adaptation to hemodynamics. Biomaterials. 2023 02; 293:121946. Kim D, Grath A, Lu YW, Chung K, Winkelman M, Schwarz JJ, Dai G. PMID: 36512862; PMCID: PMC9868097.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    12. Set7 deletion attenuates isoproterenol-induced cardiac fibrosis and delays cardiac dysfunction. Clin Sci (Lond). 2022 11 30; 136(21):1537-1554. Lunardon G, de Oliveira Silva T, Lino CA, Lu YW, Miranda JB, Asprino PF, de Almeida Silva A, Nepomuceno GT, Irigoyen MCC, Carneiro-Ramos MS, Takano APC, Martinho HDS, Barreto-Chaves MLM, Wang DZ, Diniz GP. PMID: 36285636.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    13. Epsin Nanotherapy Regulates Cholesterol Transport to Fortify Atheroma Regression. Circ Res. 2023 01 06; 132(1):e22-e42. Cui K, Gao X, Wang B, Wu H, Arulsamy K, Dong Y, Xiao Y, Jiang X, Malovichko MV, Li K, Peng Q, Lu YW, Zhu B, Zheng R, Wong S, Cowan DB, Linton M, Srivastava S, Shi J, Chen K, Chen H. PMID: 36444722; PMCID: PMC9822875.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    14. Set7 Deletion Prevents Glucose Intolerance and Improves the Recovery of Cardiac Function After Ischemia and Reperfusion in Obese Female Mice. Cell Physiol Biochem. 2022 Jun 30; 56(3):293-309. Miranda JB, Lunardon G, Lima VM, de Oliveira Silva T, Lino CA, Jensen L, Irigoyen MC, da Silva IB, Lu YW, Liu J, Donato Júnior J, Barreto-Chaves MLM, Wang DZ, Diniz GP. PMID: 35781359.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    15. The Role of Endothelial-to-Mesenchymal Transition in Cardiovascular Disease. Cells. 2022 06 03; 11(11). Peng Q, Shan D, Cui K, Li K, Zhu B, Wu H, Wang B, Wong S, Norton V, Dong Y, Lu YW, Zhou C, Chen H. PMID: 35681530; PMCID: PMC9180466.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    16. Diabetes and Its Cardiovascular Complications: Comprehensive Network and Systematic Analyses. Front Cardiovasc Med. 2022; 9:841928. Wu H, Norton V, Cui K, Zhu B, Bhattacharjee S, Lu YW, Wang B, Shan D, Wong S, Dong Y, Chan SL, Cowan D, Xu J, Bielenberg DR, Zhou C, Chen H. PMID: 35252405; PMCID: PMC8891533.
      View in: PubMed   Mentions: 8  
    17. Cardiac CIP protein regulates dystrophic cardiomyopathy. Mol Ther. 2022 02 02; 30(2):898-914. He X, Liu J, Gu F, Chen J, Lu YW, Ding J, Guo H, Nie M, Kataoka M, Lin Z, Hu X, Chen H, Liao X, Dong Y, Min W, Deng ZL, Pu WT, Huang ZP, Wang DZ. PMID: 34400329; PMCID: PMC8822131.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    18. MEF2 (Myocyte Enhancer Factor 2) Is Essential for Endothelial Homeostasis and the Atheroprotective Gene Expression Program. Arterioscler Thromb Vasc Biol. 2021 03; 41(3):1105-1123. Lu YW, Martino N, Gerlach BD, Lamar JM, Vincent PA, Adam AP, Schwarz JJ. PMID: 33406884; PMCID: PMC7938420.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    19. Deletion of miRNA-22 Induces Cardiac Hypertrophy in Females but Attenuates Obesogenic Diet-Mediated Metabolic Disorders. Cell Physiol Biochem. 2020 Dec 01; 54(6):1199-1217. de Oliveira Silva T, Lino CA, Buzatto VC, Asprino PF, Lu YW, Lima VM, Fonseca RIB, Jensen L, Murata GM, Filho SV, Ribeiro MAC, Donato JJ, Ferreira JCB, Rodrigues AC, Irigoyen MC, Barreto-Chaves MLM, Huang ZP, Galante PAF, Wang DZ, Diniz GP. PMID: 33252886.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    20. Loss of Phosphatase and Tensin Homolog Promotes Cardiomyocyte Proliferation and Cardiac Repair After Myocardial Infarction. Circulation. 2020 12; 142(22):2196-2199. Liang T, Gao F, Jiang J, Lu YW, Zhang F, Wang Y, Liu N, Fu X, Dong X, Pei J, Cowan DB, Hu X, Wang J, Wang DZ, Chen J. PMID: 33253002; PMCID: PMC7853321.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    21. Intercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart. Nat Commun. 2020 09 16; 11(1):4666. Guo H, Lu YW, Lin Z, Huang ZP, Liu J, Wang Y, Seok HY, Hu X, Ma Q, Li K, Kyselovic J, Wang Q, Lin JL, Lin JJ, Cowan DB, Naya F, Chen Y, Pu WT, Wang DZ. PMID: 32938943; PMCID: PMC7494909.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    22. Transcriptional control of a novel long noncoding RNA Mymsl in smooth muscle cells by a single Cis-element and its initial functional characterization in vessels. J Mol Cell Cardiol. 2020 01; 138:147-157. Choi M, Lu YW, Zhao J, Wu M, Zhang W, Long X. PMID: 31751568; PMCID: PMC7036038.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    23. Cell chirality regulates intercellular junctions and endothelial permeability. Sci Adv. 2018 10; 4(10):eaat2111. Fan J, Ray P, Lu YW, Kaur G, Schwarz JJ, Wan LQ. PMID: 30397640; PMCID: PMC6200360.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    24. Non-coding RNA in Ischemic and Non-ischemic Cardiomyopathy. Curr Cardiol Rep. 2018 09 26; 20(11):115. Lu YW, Wang DZ. PMID: 30259174.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    25. Transforming growth factor β1 suppresses proinflammatory gene program independent of its regulation on vascular smooth muscle differentiation and autophagy. Cell Signal. 2018 Oct; 50:160-170. Gao P, Wu W, Ye J, Lu YW, Adam AP, Singer HA, Long X. PMID: 30006123; PMCID: PMC6389266.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    26. Endothelial Myocyte Enhancer Factor 2c Inhibits Migration of Smooth Muscle Cells Through Fenestrations in the Internal Elastic Lamina. Arterioscler Thromb Vasc Biol. 2017 07; 37(7):1380-1390. Lu YW, Lowery AM, Sun LY, Singer HA, Dai G, Adam AP, Vincent PA, Schwarz JJ. PMID: 28473437; PMCID: PMC5527298.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    27. Selective expression of TSPAN2 in vascular smooth muscle is independently regulated by TGF-β1/SMAD and myocardin/serum response factor. FASEB J. 2017 06; 31(6):2576-2591. Zhao J, Wu W, Zhang W, Lu YW, Tou E, Ye J, Gao P, Jourd'heuil D, Singer HA, Wu M, Long X. PMID: 28258189; PMCID: PMC5434656.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    28. MEF2 transcription factors are key regulators of sprouting angiogenesis. Genes Dev. 2016 Oct 15; 30(20):2297-2309. Sacilotto N, Chouliaras KM, Nikitenko LL, Lu YW, Fritzsche M, Wallace MD, Nornes S, García-Moreno F, Payne S, Bridges E, Liu K, Biggs D, Ratnayaka I, Herbert SP, Molnár Z, Harris AL, Davies B, Bond GL, Bou-Gharios G, Schwarz JJ, De Val S. PMID: 27898394; PMCID: PMC5110996.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    29. Venous Endothelial Marker COUP-TFII Regulates the Distinct Pathologic Potentials of Adult Arteries and Veins. Sci Rep. 2015 Nov 05; 5:16193. Cui X, Lu YW, Lee V, Kim D, Dorsey T, Wang Q, Lee Y, Vincent P, Schwarz J, Dai G. PMID: 26537113; PMCID: PMC4633649.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    30. Insulin-like growth factor-1 receptor activation prevents high glucose-induced mitochondrial dysfunction, cytochrome-c release and apoptosis. Biochem Biophys Res Commun. 2009 Jun 26; 384(2):259-64. Li Y, Wu H, Khardori R, Song YH, Lu YW, Geng YJ. PMID: 19406106.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    31. MicroRNA-221 regulates high glucose-induced endothelial dysfunction. Biochem Biophys Res Commun. 2009 Mar 27; 381(1):81-3. Li Y, Song YH, Li F, Yang T, Lu YW, Geng YJ. PMID: 19351599; PMCID: PMC2670889.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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