Roger Edward De Filippo, MD

Title(s)Associate Professor of Urology (Clinical Scholar)
AddressCHL MailStop114
Off Campus
Los Angeles CA 90089
Phone+1 323 361 7641
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    Other Positions
    Title(s)Chief of Pediatric Urology


    Collapse Research 
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    Renal Tissue Derived From Amniotic Fluid Stem Cells
    NIH K08DK073082Sep 30, 2005 - Nov 30, 2011
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Association between severity of prenatally diagnosed hydronephrosis and receipt of surgical intervention postnatally among patients seen at a fetal-maternal center. BMC Urol. 2021 Apr 07; 21(1):54. Baker ZG, Hannallah A, Trabold M, Estell D, Deng C, Chang AY, Sparks SS, De Filippo R, Vasquez E. PMID: 33827528.
      View in: PubMed   Mentions:    Fields:    
    2. Glomerular endothelial cell heterogeneity in Alport syndrome. Sci Rep. 2020 07 10; 10(1):11414. Soloyan H, Thornton M, Villani V, Khatchadourian P, Cravedi P, Angeletti A, Grubbs B, De Filippo R, Perin L, Sedrakyan S. PMID: 32651395.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. Absence of Testicular Adrenal Rest Tumors in Newborns, Infants, and Toddlers with Classical Congenital Adrenal Hyperplasia. Horm Res Paediatr. 2019; 92(3):157-161. Kim MS, Koppin CM, Mohan P, Goodarzian F, Ross HM, Geffner ME, De Filippo R, Kokorowski P. PMID: 31747670.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Author Correction: A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier. Nat Commun. 2019 Oct 21; 10(1):4791. Petrosyan A, Cravedi P, Villani V, Angeletti A, Manrique J, Renieri A, De Filippo RE, Perin L, Da Sacco S. PMID: 31636254.
      View in: PubMed   Mentions:    Fields:    
    5. SOX9+/PTF1A+ Cells Define the Tip Progenitor Cells of the Human Fetal Pancreas of the Second Trimester. Stem Cells Transl Med. 2019 12; 8(12):1249-1264. Villani V, Thornton ME, Zook HN, Crook CJ, Grubbs BH, Orlando G, De Filippo R, Ku HT, Perin L. PMID: 31631582.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    6. A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier. Nat Commun. 2019 Aug 13; 10(1):3656. Petrosyan A, Cravedi P, Villani V, Angeletti A, Manrique J, Renieri A, De Filippo RE, Perin L, Da Sacco S. PMID: 31409793.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    7. Testicular Adrenal Rest Tumors in Boys and Young Adults with Congenital Adrenal Hyperplasia. J Urol. 2017 03; 197(3 Pt 2):931-936. Kim MS, Goodarzian F, Keenan MF, Geffner ME, Koppin CM, De Filippo RE, Kokorowski PJ. PMID: 27840017.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    8. Direct Isolation and Characterization of Human Nephron Progenitors. Stem Cells Transl Med. 2017 02; 6(2):419-433. Da Sacco S, Thornton ME, Petrosyan A, Lavarreda-Pearce M, Sedrakyan S, Grubbs BH, De Filippo RE, Perin L. PMID: 28191781.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    9. A step towards clinical application of acellular matrix: A clue from macrophage polarization. Matrix Biol. 2017 01; 57-58:334-346. Petrosyan A, Da Sacco S, Tripuraneni N, Kreuser U, Lavarreda-Pearce M, Tamburrini R, De Filippo RE, Orlando G, Cravedi P, Perin L. PMID: 27575985.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    10. Decellularized Renal Matrix and Regenerative Medicine of the Kidney: A Different Point of View. Tissue Eng Part B Rev. 2016 06; 22(3):183-92. Petrosyan A, Zanusso I, Lavarreda-Pearce M, Leslie S, Sedrakyan S, De Filippo RE, Orlando G, Da Sacco S, Perin L. PMID: 26653996.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    11. Aberrant Activation of Notch Signaling Inhibits PROX1 Activity to Enhance the Malignant Behavior of Thyroid Cancer Cells. Cancer Res. 2016 Feb 01; 76(3):582-93. Choi D, Ramu S, Park E, Jung E, Yang S, Jung W, Choi I, Lee S, Kim KE, Seong YJ, Hong M, Daghlian G, Kim D, Shin E, Seo JI, Khatchadourian V, Zou M, Li W, De Filippo R, Kokorowski P, Chang A, Kim S, Bertoni A, Furlanetto TW, Shin S, Li M, Chen Y, Wong A, Koh C, Geliebter J, Hong YK. PMID: 26609053.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    12. Renal Extracellular Matrix Scaffolds From Discarded Kidneys Maintain Glomerular Morphometry and Vascular Resilience and Retains Critical Growth Factors. Transplantation. 2015 Sep; 99(9):1807-16. Peloso A, Petrosyan A, Da Sacco S, Booth C, Zambon JP, O'Brien T, Aardema C, Robertson J, De Filippo RE, Soker S, Stratta RJ, Perin L, Orlando G. PMID: 26018349.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    13. A novel source of cultured podocytes. PLoS One. 2013; 8(12):e81812. Da Sacco S, Lemley KV, Sedrakyan S, Zanusso I, Petrosyan A, Peti-Peterdi J, Burford J, De Filippo RE, Perin L. PMID: 24349133.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    14. Amniotic fluid stem cells prevent ß-cell injury. Cytotherapy. 2014 Jan; 16(1):41-55. Villani V, Milanesi A, Sedrakyan S, Da Sacco S, Angelow S, Conconi MT, Di Liddo R, De Filippo R, Perin L. PMID: 24210784.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    15. Autologous cell seeded biodegradable scaffold for augmentation cystoplasty: phase II study in children and adolescents with spina bifida. J Urol. 2014 May; 191(5):1389-95. Joseph DB, Borer JG, De Filippo RE, Hodges SJ, McLorie GA. PMID: 24184366.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCTClinical Trials
    16. Anorectal malformation and associated end-stage renal disease: management from newborn to adult life. J Pediatr Surg. 2013 Mar; 48(3):635-41. Giuliani S, Midrio P, De Filippo RE, Vidal E, Castagnetti M, Zanon GF, Gamba PG. PMID: 23480924.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    17. Cryptorchidism and testicular germ cell tumors: comprehensive meta-analysis reveals that association between these conditions diminished over time and is modified by clinical characteristics. Front Endocrinol (Lausanne). 2012; 3:182. Banks K, Tuazon E, Berhane K, Koh CJ, De Filippo RE, Chang A, Kim SS, Daneshmand S, Davis-Dao C, Lewinger JP, Bernstein L, Cortessis VK. PMID: 23423470.
      View in: PubMed   Mentions:
    18. Penile urethra replacement with autologous cell-seeded tubularized collagen matrices. J Tissue Eng Regen Med. 2015 Mar; 9(3):257-64. De Filippo RE, Kornitzer BS, Yoo JJ, Atala A. PMID: 23172803.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    19. Injection of amniotic fluid stem cells delays progression of renal fibrosis. J Am Soc Nephrol. 2012 Apr; 23(4):661-73. Sedrakyan S, Da Sacco S, Milanesi A, Shiri L, Petrosyan A, Varimezova R, Warburton D, Lemley KV, De Filippo RE, Perin L. PMID: 22302195.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    20. Stem cells as a therapeutic approach to chronic kidney diseases. Curr Urol Rep. 2012 Feb; 13(1):47-54. Sedrakyan S, Angelow S, De Filippo RE, Perin L. PMID: 22127675.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    21. Shorter androgen receptor CAG repeat lengths associated with cryptorchidism risk among Hispanic white boys. J Clin Endocrinol Metab. 2012 Mar; 97(3):E393-9. Davis-Dao C, Koh CJ, Hardy BE, Chang A, Kim SS, De Filippo R, Hwang A, Pike MC, Carroll JD, Coetzee GA, Vandenberg D, Siegmund K, Cortessis VK. PMID: 22188741.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    22. Human capital gains associated with robotic assisted laparoscopic pyeloplasty in children compared to open pyeloplasty. J Urol. 2011 Oct; 186(4 Suppl):1663-7. Behan JW, Kim SS, Dorey F, De Filippo RE, Chang AY, Hardy BE, Koh CJ. PMID: 21862079.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    23. Early comparison of nephrectomy options in children (open, transperitoneal laparoscopic, laparo-endoscopic single site (LESS), and robotic surgery). BJU Int. 2012 Mar; 109(6):910-5. Kim PH, Patil MB, Kim SS, Dorey F, De Filippo RE, Chang AY, Hardy BE, Gill IS, Desai MM, Koh CJ. PMID: 21883858.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    24. The milieu of damaged alveolar epithelial type 2 cells stimulates alveolar wound repair by endogenous and exogenous progenitors. Am J Respir Cell Mol Biol. 2011 Dec; 45(6):1212-21. Buckley S, Shi W, Carraro G, Sedrakyan S, Da Sacco S, Driscoll BA, Perin L, De Filippo RE, Warburton D. PMID: 21700959.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    25. Editorial comment. Urology. 2011 May; 77(5):1253; author reply 1253. Kokorowski P, De Filippo RE, Koh CJ. PMID: 21539975.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Amniotic fluid as a source of pluripotent and multipotent stem cells for organ regeneration. Curr Opin Organ Transplant. 2011 Feb; 16(1):101-5. Da Sacco S, De Filippo RE, Perin L. PMID: 21157345.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    27. Regenerative medicine of the kidney. Adv Drug Deliv Rev. 2011 Apr 30; 63(4-5):379-87. Perin L, Da Sacco S, De Filippo RE. PMID: 21145933.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    28. Laparoendoscopic single-site nephrectomy in pediatric patients: initial clinical series of infants to adolescents. Urology. 2010 Dec; 76(6):1457-61. Koh CJ, De Filippo RE, Chang AY, Hardy BE, Berger A, Eisenberg M, Patil M, Aron M, Gill IS, Desai MM. PMID: 20970837.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    29. Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis. PLoS One. 2010 Feb 24; 5(2):e9357. Perin L, Sedrakyan S, Giuliani S, Da Sacco S, Carraro G, Shiri L, Lemley KV, Rosol M, Wu S, Atala A, Warburton D, De Filippo RE. PMID: 20195358.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    30. Human amniotic fluid as a potential new source of organ specific precursor cells for future regenerative medicine applications. J Urol. 2010 Mar; 183(3):1193-200. Da Sacco S, Sedrakyan S, Boldrin F, Giuliani S, Parnigotto P, Habibian R, Warburton D, De Filippo RE, Perin L. PMID: 20096867.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    31. Complementary roles of sonography and magnetic resonance imaging in the assessment of fetal urinary tract anomalies. J Ultrasound Med. 2008 Nov; 27(11):1563-9. Barseghyan K, Jackson HA, Chmait R, De Filippo RE, Miller DA. PMID: 18946095.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Pediatric robot-assisted laparoscopic excision of urachal cyst and bladder cuff. J Endourol. 2008 Oct; 22(10):2385-8; discussion 2388. Yamzon J, Kokorowski P, De Filippo RE, Chang AY, Hardy BE, Koh CJ. PMID: 18937602.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages. Stem Cells. 2008 Nov; 26(11):2902-11. Carraro G, Perin L, Sedrakyan S, Giuliani S, Tiozzo C, Lee J, Turcatel G, De Langhe SP, Driscoll B, Bellusci S, Minoo P, Atala A, De Filippo RE, Warburton D. PMID: 18719226.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    34. Tubularized urethral replacement with unseeded matrices: what is the maximum distance for normal tissue regeneration? World J Urol. 2008 Aug; 26(4):323-6. Dorin RP, Pohl HG, De Filippo RE, Yoo JJ, Atala A. PMID: 18682960.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    35. Tissue engineering a complete vaginal replacement from a small biopsy of autologous tissue. Transplantation. 2008 Jul 27; 86(2):208-14. De Filippo RE, De Philippo RE, Bishop CE, Filho LF, Yoo JJ, Atala A. PMID: 18645481.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    36. Re: Prepubertal orchiopexy for cryptorchidism may be associated with lower risk of testicular cancer. J Urol. 2008 Aug; 180(2):783-4; author reply 784-5. Tuazon E, Banks K, Koh CJ, De Filippo RE, Chang A, Hardy BE, Cortessis VK. PMID: 18555491.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    37. Stem cell and regenerative science applications in the development of bioengineering of renal tissue. Pediatr Res. 2008 May; 63(5):467-71. Perin L, Giuliani S, Sedrakyan S, DA Sacco S, De Filippo RE. PMID: 18427289.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    38. Characterization of human amniotic fluid stem cells and their pluripotential capability. Methods Cell Biol. 2008; 86:85-99. Perin L, Sedrakyan S, Da Sacco S, De Filippo R. PMID: 18442645.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    39. Ex vivo whole embryonic kidney culture: a novel method for research in development, regeneration and transplantation. J Urol. 2008 Jan; 179(1):365-70. Giuliani S, Perin L, Sedrakyan S, Kokorowski P, Jin D, De Filippo R. PMID: 18006007.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    40. Engineering of vaginal tissue in vivo. Tissue Eng. 2003 Apr; 9(2):301-6. De Filippo RE, Yoo JJ, Atala A. PMID: 12740092.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    41. Urethral replacement using cell seeded tubularized collagen matrices. J Urol. 2002 Oct; 168(4 Pt 2):1789-92; discussion 1792-3. De Filippo RE, Yoo JJ, Atala A. PMID: 12352360.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
    42. Stretch and growth: the molecular and physiologic influences of tissue expansion. Plast Reconstr Surg. 2002 Jun; 109(7):2450-62. De Filippo RE, Atala A. PMID: 12045576.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
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