Giorgio Casaburi

Photo of Giorgio Casaburi
Title(s)Part-Time Lecturer for the Department of Cancer Biology
SchoolKeck School of Medicine of Usc
Address1441 Eastlake Avenue
Health Sciences Campus
Los Angeles CA 90033
ORCID ORCID Icon0000-0002-5980-8704 Additional info
vCardDownload vCard

    Collapse Overview 
    Collapse overview
    Dr. Giorgio Casaburi is a bioinformatics scientist and translational genomics researcher specializing in artificial intelligence, multi-omics data integration, and precision medicine. His work focuses on developing clinically actionable molecular diagnostics and computational platforms that translate complex biological data into real-world healthcare applications.

    Dr. Casaburi has over 15 years of experience leading genomics, transcriptomics, methylomics, metagenomics, and machine learning initiatives across academia, biotechnology, and regulated diagnostics environments. His research spans cancer biology, microbiome science, biomarker discovery, translational AI, and predictive modeling for therapeutic response and disease stratification.

    He has led the development and validation of multiple AI-driven diagnostic and bioinformatics platforms, including CLIA-oriented molecular workflows and clinical decision-support systems. His work integrates next-generation sequencing, cloud-scale bioinformatics infrastructure, and machine learning approaches to accelerate translational research and precision oncology applications.

    Prior to joining USC, Dr. Casaburi held leadership roles in biotechnology and molecular diagnostics organizations, including SOLVD Health, Exagen, Prescient Metabiomics, and Evolve Biosystems. He has authored more than 70 peer-reviewed publications, contributed to multiple patents in diagnostics and AI-enabled healthcare technologies, and has presented research at major international scientific conferences.

    At USC, his academic interests include translational genomics, AI-driven biomedical research, computational oncology, and the application of machine learning to molecular diagnostics and precision medicine.

    Collapse Bibliographic 
    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Randomized, placebo-controlled trial reveals the impact of dose and timing of Bifidobacterium infantis probiotic supplementation on breastfed infants' gut microbiome. mSphere. 2026 Jan 27; 11(1):e0051825. O'Brien CE, Frese SA, Cernioglo K, Damian-Medina K, Mitchell RD, Casaburi G, Melnyk RA, Henrick BM, Smilowitz JT. PMID: 41427732; PMCID: PMC12838401.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    2. Gut mucosa-associated microbiota signatures in healthy individuals and patients at different stages of liver disease: a pilot study. Gut Pathog. 2025 Dec 08; 17(1):99. Compare D, Fosso B, Nunziato M, Sgamato C, Di Maggio F, D'Argenio V, Granata I, Zamparelli MS, Lovero D, Casaburi G, Rocco A, Coccoli P, Pesole G, Salvatore F, Nardone G. PMID: 41361834; PMCID: PMC12683826.
      View in: PubMed   Mentions:
    3. Establishing Best Practices for Clinical GWAS: Tackling Imputation and Data Quality Challenges. Int J Mol Sci. 2025 Jul 03; 26(13). Casaburi G, McCullough R, D'Argenio V. PMID: 40650174; PMCID: PMC12250051.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    4. Metabolic model of necrotizing enterocolitis in the premature newborn gut resulting from enteric dysbiosis. Front Pediatr. 2022; 10:893059. Casaburi G, Wei J, Kazi S, Liu J, Wang K, Tao GZ, Lin PY, Dunn JCY, Henrick BM, Frese SA, Sylvester KG. PMID: 36081629; PMCID: PMC9445129.
      View in: PubMed   Mentions: 17  
    5. Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutrition. Sci Transl Med. 2022 04 13; 14(640):eabk1107. Barratt MJ, Nuzhat S, Ahsan K, Frese SA, Arzamasov AA, Sarker SA, Islam MM, Palit P, Islam MR, Hibberd MC, Nakshatri S, Cowardin CA, Guruge JL, Byrne AE, Venkatesh S, Sundaresan V, Henrick B, Duar RM, Mitchell RD, Casaburi G, Prambs J, Flannery R, Mahfuz M, Rodionov DA, Osterman AL, Kyle D, Ahmed T, Gordon JI. PMID: 35417188; PMCID: PMC9516695.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    6. Bifidobacterium longum Subspecies infantis Strain EVC001 Decreases Neonatal Murine Necrotizing Enterocolitis. Nutrients. 2022 Jan 24; 14(3). Lueschow SR, Boly TJ, Frese SA, Casaburi G, Mitchell RD, Henrick BM, McElroy SJ. PMID: 35276854; PMCID: PMC8839161.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    7. Microbiome composition indicate dysbiosis and lower richness in tumor breast tissues compared to healthy adjacent paired tissue, within the same women. BMC Cancer. 2022 Jan 03; 22(1):30. Esposito MV, Fosso B, Nunziato M, Casaburi G, D'Argenio V, Calabrese A, D'Aiuto M, Botti G, Pesole G, Salvatore F. PMID: 34980006; PMCID: PMC8722097.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    8. Multidisciplinary In-Depth Investigation in a Young Athlete Suffering from Syncope Caused by Myocardial Bridge. Diagnostics (Basel). 2021 Nov 19; 11(11). Brancaccio M, Mennitti C, Cesaro A, Monda E, D'Argenio V, Casaburi G, Mazzaccara C, Ranieri A, Fimiani F, Barretta F, Uomo F, Caiazza M, Lioncino M, D'Alicandro G, Limongelli G, Calabrò P, Terracciano D, Lombardo B, Frisso G, Scudiero O. PMID: 34829491; PMCID: PMC8618222.
      View in: PubMed   Mentions: 11  
    9. Author Correction: Metagenomic insights of the infant microbiome community structure and function across multiple sites in the United States. Sci Rep. 2021 May 20; 11(1):11050. Casaburi G, Duar RM, Brown H, Mitchell RD, Kazi S, Chew S, Cagney O, Flannery RL, Sylvester KG, Frese SA, Henrick BM, Freeman SL. PMID: 34017057; PMCID: PMC8137686.
      View in: PubMed   Mentions: 3     Fields:    
    10. Early probiotic supplementation with B. infantis in breastfed infants leads to persistent colonization at 1 year. Pediatr Res. 2022 02; 91(3):627-636. O'Brien CE, Meier AK, Cernioglo K, Mitchell RD, Casaburi G, Frese SA, Henrick BM, Underwood MA, Smilowitz JT. PMID: 33762689; PMCID: PMC8460680.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    11. Impact of Probiotic B. infantis EVC001 Feeding in Premature Infants on the Gut Microbiome, Nosocomially Acquired Antibiotic Resistance, and Enteric Inflammation. Front Pediatr. 2021; 9:618009. Nguyen M, Holdbrooks H, Mishra P, Abrantes MA, Eskew S, Garma M, Oca CG, McGuckin C, Hein CB, Mitchell RD, Kazi S, Chew S, Casaburi G, Brown HK, Frese SA, Henrick BM. PMID: 33665175; PMCID: PMC7921802.
      View in: PubMed   Mentions: 37  
    12. Metagenomic insights of the infant microbiome community structure and function across multiple sites in the United States. Sci Rep. 2021 01 21; 11(1):1472. Casaburi G, Duar RM, Brown H, Mitchell RD, Kazi S, Chew S, Cagney O, Flannery RL, Sylvester KG, Frese SA, Henrick BM, Freeman SL. PMID: 33479326; PMCID: PMC7820601.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    13. Comparative Genome Analysis of Bifidobacterium longum subsp. infantis Strains Reveals Variation in Human Milk Oligosaccharide Utilization Genes among Commercial Probiotics. Nutrients. 2020 Oct 23; 12(11). Duar RM, Casaburi G, Mitchell RD, Scofield LNC, Ortega Ramirez CA, Barile D, Henrick BM, Frese SA. PMID: 33114073; PMCID: PMC7690671.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    14. Digital Proxy of a Bio-Reactor (DIYBOT) combines sensor data and data analytics to improve greywater treatment and wastewater management systems. Sci Rep. 2020 05 15; 10(1):8015. McLamore ES, Huffaker R, Shupler M, Ward K, Datta SPA, Katherine Banks M, Casaburi G, Babilonia J, Foster JS. PMID: 32415099; PMCID: PMC7229150.
      View in: PubMed   Mentions: 1     Fields:    
    15. Integrating the Ecosystem Services Framework to Define Dysbiosis of the Breastfed Infant Gut: The Role of B. infantis and Human Milk Oligosaccharides. Front Nutr. 2020; 7:33. Duar RM, Henrick BM, Casaburi G, Frese SA. PMID: 32346537; PMCID: PMC7171047.
      View in: PubMed   Mentions: 33  
    16. Colonization Resistance in the Infant Gut: The Role of B. infantis in Reducing pH and Preventing Pathogen Growth. High Throughput. 2020 Mar 27; 9(2). Duar RM, Kyle D, Casaburi G. PMID: 32230716; PMCID: PMC7349288.
      View in: PubMed   Mentions: 28  
    17. A common microbial signature is present in the lower airways of interstitial lung diseases including sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2018; 35(4):354-362. D'Argenio V, Casaburi G, Precone V, Gioacchino Moccia L, Postiglione I, Bocchino M, Sanduzzi A. PMID: 32476923; PMCID: PMC7170129.
      View in: PubMed   Mentions: 7     Fields:    
    18. Colonization by B. infantis EVC001 modulates enteric inflammation in exclusively breastfed infants. Pediatr Res. 2019 12; 86(6):749-757. Henrick BM, Chew S, Casaburi G, Brown HK, Frese SA, Zhou Y, Underwood MA, Smilowitz JT. PMID: 31443102; PMCID: PMC6887859.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCells
    19. Early-life gut microbiome modulation reduces the abundance of antibiotic-resistant bacteria. Antimicrob Resist Infect Control. 2019; 8:131. Casaburi G, Duar RM, Vance DP, Mitchell R, Contreras L, Frese SA, Smilowitz JT, Underwood MA. PMID: 31423298; PMCID: PMC6693174.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    20. GenCoF: a graphical user interface to rapidly remove human genome contaminants from metagenomic datasets. Bioinformatics. 2019 07 01; 35(13):2318-2319. Czajkowski MD, Vance DP, Frese SA, Casaburi G. PMID: 30475995; PMCID: PMC6596892.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    21. Genomic evidence of the illumination response mechanism and evolutionary history of magnetotactic bacteria within the Rhodospirillaceae family. BMC Genomics. 2019 May 22; 20(1):407. Wang Y, Casaburi G, Lin W, Li Y, Wang F, Pan Y. PMID: 31117953; PMCID: PMC6532209.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    22. Symbiotic organs shaped by distinct modes of genome evolution in cephalopods. Proc Natl Acad Sci U S A. 2019 02 19; 116(8):3030-3035. Belcaid M, Casaburi G, McAnulty SJ, Schmidbaur H, Suria AM, Moriano-Gutierrez S, Pankey MS, Oakley TH, Kremer N, Koch EJ, Collins AJ, Nguyen H, Lek S, Goncharenko-Foster I, Minx P, Sodergren E, Weinstock G, Rokhsar DS, McFall-Ngai M, Simakov O, Foster JS, Nyholm SV. PMID: 30635418; PMCID: PMC6386654.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    23. Reduced colonic mucin degradation in breastfed infants colonized by Bifidobacterium longum subsp. infantis EVC001. FEBS Open Bio. 2018 Oct; 8(10):1649-1657. Karav S, Casaburi G, Frese SA. PMID: 30338216; PMCID: PMC6168692.
      View in: PubMed   Mentions: 36     Fields:    
    24. Oropharyngeal microbiome evaluation highlights Neisseria abundance in active celiac patients. Sci Rep. 2018 07 23; 8(1):11047. Iaffaldano L, Granata I, Pagliuca C, Esposito MV, Casaburi G, Salerno G, Colicchio R, Piccirillo M, Ciacci C, Del Vecchio Blanco G, Guarracino MR, Salvatore P, Salvatore F, D'Argenio V, Sacchetti L. PMID: 30038321; PMCID: PMC6056421.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    25. Comparative Metagenomics Provides Insight Into the Ecosystem Functioning of the Shark Bay Stromatolites, Western Australia. Front Microbiol. 2018; 9:1359. Babilonia J, Conesa A, Casaburi G, Pereira C, Louyakis AS, Reid RP, Foster JS. PMID: 29988640; PMCID: PMC6027182.
      View in: PubMed   Mentions: 19  
    26. Elevated Fecal pH Indicates a Profound Change in the Breastfed Infant Gut Microbiome Due to Reduction of Bifidobacterium over the Past Century. mSphere. 2018 Mar-Apr; 3(2). Henrick BM, Hutton AA, Palumbo MC, Casaburi G, Mitchell RD, Underwood MA, Smilowitz JT, Frese SA. PMID: 29564397; PMCID: PMC5853487.
      View in: PubMed   Mentions: 89     Fields:    
    27. A year in the life of a thrombolite: comparative metatranscriptomics reveals dynamic metabolic changes over diel and seasonal cycles. Environ Microbiol. 2018 02; 20(2):842-861. Louyakis AS, Gourlé H, Casaburi G, Bonjawo RME, Duscher AA, Foster JS. PMID: 29266662.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    28. Persistence of Supplemented Bifidobacterium longum subsp. infantis EVC001 in Breastfed Infants. mSphere. 2017 Nov-Dec; 2(6). Frese SA, Hutton AA, Contreras LN, Shaw CA, Palumbo MC, Casaburi G, Xu G, Davis JCC, Lebrilla CB, Henrick BM, Freeman SL, Barile D, German JB, Mills DA, Smilowitz JT, Underwood MA. PMID: 29242832; PMCID: PMC5717325.
      View in: PubMed   Mentions: 140     Fields:    
    29. A Study of the Microbial Spatial Heterogeneity of Bahamian Thrombolites Using Molecular, Biochemical, and Stable Isotope Analyses. Astrobiology. 2017 May; 17(5):413-430. Louyakis AS, Mobberley JM, Vitek BE, Visscher PT, Hagan PD, Reid RP, Kozdon R, Orland IJ, Valley JW, Planavsky NJ, Casaburi G, Foster JS. PMID: 28520472; PMCID: PMC5767104.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    30. Transcriptomic changes in an animal-bacterial symbiosis under modeled microgravity conditions. Sci Rep. 2017 04 10; 7:46318. Casaburi G, Goncharenko-Foster I, Duscher AA, Foster JS. PMID: 28393904; PMCID: PMC5385879.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    31. The Cause of Death of a Child in the 18th Century Solved by Bone Microbiome Typing Using Laser Microdissection and Next Generation Sequencing. Int J Mol Sci. 2017 Jan 06; 18(1). D'Argenio V, Torino M, Precone V, Casaburi G, Esposito MV, Iaffaldano L, Malapelle U, Troncone G, Coto I, Cavalcanti P, De Rosa G, Salvatore F, Sacchetti L. PMID: 28067829; PMCID: PMC5297743.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    32. Corrigendum: No Change in the Mucosal Gut Microbiome is Associated with Celiac Disease-Specific Microbiome Alteration in Adult Patients. Am J Gastroenterol. 2017 01; 112(1):193. D'Argenio V, Casaburi G, Precone V, Pagliuca C, Colicchio R, Sarnataro D, Discepolo V, Kim SM, Russo I, Del Vecchio Blanco G, Horner DS, Chiara M, Pesole G, Salvatore P, Monteleone G, Ciacci C, Caporaso GJ, Jabrì B, Salvatore F, Sacchetti L. PMID: 27958280.
      View in: PubMed   Mentions:    Fields:    
    33. No Change in the Mucosal Gut Mycobioma Is Associated with Celiac Disease-Specific Microbiome Alteration in Adult Patients. Am J Gastroenterol. 2016 11; 111(11):1659-1661. D'Argenio V, Casaburi G, Precone V, Pagliuca C, Colicchio R, Sarnataro D, Discepolo V, Kim SM, Russo I, Del Vecchio Blanco G, Horner DS, Chiara M, Pesole G, Salvatore P, Monteleone G, Ciacci C, Caporaso GJ, Jabrì B, Salvatore F, Sacchetti L. PMID: 27808136.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    34. Characterization of Microbial Mat Microbiomes in the Modern Thrombolite Ecosystem of Lake Clifton, Western Australia Using Shotgun Metagenomics. Front Microbiol. 2016; 7:1064. Warden JG, Casaburi G, Omelon CR, Bennett PC, Breecker DO, Foster JS. PMID: 27458453; PMCID: PMC4933708.
      View in: PubMed   Mentions: 14  
    35. Metagenomics Reveals Dysbiosis and a Potentially Pathogenic N. flavescens Strain in Duodenum of Adult Celiac Patients. Am J Gastroenterol. 2016 Jun; 111(6):879-90. D'Argenio V, Casaburi G, Precone V, Pagliuca C, Colicchio R, Sarnataro D, Discepolo V, Kim SM, Russo I, Del Vecchio Blanco G, Horner DS, Chiara M, Pesole G, Salvatore P, Monteleone G, Ciacci C, Caporaso GJ, Jabrì B, Salvatore F, Sacchetti L. PMID: 27045926; PMCID: PMC4897008.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    36. Characterization of the stromatolite microbiome from Little Darby Island, The Bahamas using predictive and whole shotgun metagenomic analysis. Environ Microbiol. 2016 05; 18(5):1452-69. Casaburi G, Duscher AA, Reid RP, Foster JS. PMID: 26471001; PMCID: PMC5767316.
      View in: PubMed   Mentions: 13     Fields:    
    37. Comparative metagenomic analysis of human gut microbiome composition using two different bioinformatic pipelines. Biomed Res Int. 2014; 2014:325340. D'Argenio V, Casaburi G, Precone V, Salvatore F. PMID: 24719854; PMCID: PMC3955645.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    38. The personal human oral microbiome obscures the effects of treatment on periodontal disease. PLoS One. 2014; 9(1):e86708. Schwarzberg K, Le R, Bharti B, Lindsay S, Casaburi G, Salvatore F, Saber MH, Alonaizan F, Slots J, Gottlieb RA, Caporaso JG, Kelley ST. PMID: 24489772; PMCID: PMC3906071.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCellsCTClinical Trials
    39. An altered gut microbiome profile in a child affected by Crohn's disease normalized after nutritional therapy. Am J Gastroenterol. 2013 May; 108(5):851-2. D'Argenio V, Precone V, Casaburi G, Miele E, Martinelli M, Staiano A, Salvatore F, Sacchetti L. PMID: 23644964; PMCID: PMC3647232.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    Giorgio's Networks
    Concepts (139)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (3)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

    This site is running Profiles RNS version UCSF-v3.1.0-40-gb10dcd06 on PROFILES-PWEB03. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.