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Christopher Orlando

Photo of Christopher Orlando
Title(s)Assistant Professor of Clinical Neurology
SchoolKeck School of Medicine of Usc
Address1520 San Pablo St.
Health Sciences Campus
Los Angeles CA 90033
ORCID ORCID Icon0000-0001-9357-7076 Additional info
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    Collapse Biography 
    Collapse education and training
    University of Utah School of Medicine, Salt Lake City, UTMD05/2019
    University of Utah School of Medicine, Salt Lake City, UTMPH05/2019
    University of Texas Health Science Center at Houston, Houston, TX06/2023Neurology
    Keck School of Medicine of USC, Los Angeles, CA06/2025MS/Neuroimmunology
    Keck School of Medicine of USC, Los Angeles, CAgraduate certificate05/2025Clinical Translational Research
    Collapse awards and honors
    National MS Society2023  - 2025Sylvia Lawry Physician Fellowship

    Collapse Overview 
    Collapse overview
    Dr. Orlando is a clinician-scientist focusing on multiple sclerosis (MS) and related disorders. His research examines the relationship of social determinants of health with MS care and outcomes, including the ways inequities give rise to health health disparities. Current projects include investigations of the causes of delayed diagnosis of MS and how these may differ among demographic groups.

    Collapse Research 
    Collapse research activities and funding
    Identifying Intervenable Factors Related to Delayed Diagnosis of Multiple Sclerosis
    National Institutes of Health KL2TR001854Apr 1, 2026 - Mar 31, 2029
    Role: KL2 Scholar in Mentored Career Development in Clinical Translational Science (MCD-CTS) Program
    Description: The goal of this study is to identify non-medical factors related to delayed diagnosis of multiple sclerosis (MS) and how these may differ among demographic groups so that targeted strategies to improve timely diagnosis can be developed. Medical records of people with MS will be used to identify patient-, physician, and healthcare system-level barriers to healthcare access. Data from a registry of Hispanic people with MS will be analyzed to examine associations between comorbid conditions and delayed diagnosis of MS.
    Factors Associated with Delayed Diagnosis and Treatment of Multiple Sclerosis
    Race to Erase MS Jan 1, 2026 - Dec 30, 2026
    Role: principal invesitgator
    Research Training for Neurosurgery and Neurology Residents & Fellows
    NIH R25NS113757Jul 1, 2020 - Jun 30, 2025
    Role: Co-Investigator
    Description: This study examined whether neighborhood-level indicators of social determinants of health were associated with differences in neurologic disability outcomes among Black, Hispanic, and White people with multiple sclerosis.

    Collapse ORNG Applications 
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    Collapse Faculty Mentoring

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ethnoracial disparities in gray matter atrophy are mediated by structural disconnectivity in multiple sclerosis. Ann Clin Transl Neurol. 2025 Mar; 12(3):615-630. Bayoumi A, Thomas JA, Alonzo BR, Jimenez J, Orlando CM, Pérez CA, Hasan KM, Wolinsky JS, Lincoln JA. PMID: 39957675; PMCID: PMC11920733.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Person-Centered Social Determinants and Neighborhood-Level Deprivation Associated With Disability in Hispanic People With Multiple Sclerosis. Neurology. 2025 Feb 11; 104(3):e213332. Amezcua L, Cardenas-Iniguez C, Orlando C, Martinez A, Nahar I, Delgado SR, Manrique CP, Vicente I, Chinea A, McCauley JL, Islam KTS. PMID: 39819097.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. A tale of race and B cells in multiple sclerosis. Nat Rev Neurol. 2024 01; 20(1):5-6. Orlando CM, Amezcua L. PMID: 37990136.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Multiple Sclerosis in Black and Hispanic Populations: Serving the Underserved. Neurol Clin. 2024 Feb; 42(1):295-317. Williams MJ, Orlando C, Akisanya J, Amezcua L. PMID: 37980120.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    5. Social determinants of health and disparate disability accumulation in a cohort of Black, Hispanic, and White patients with multiple sclerosis. Mult Scler. 2023 09; 29(10):1304-1315. Orlando CM, Pérez CA, Agyei P, Elsehety M, Singh SK, Thomas J, Alaina O, Lincoln JA. PMID: 37435828; PMCID: PMC10503235.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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