Aram Modrek

Title(s)Assistant Professor of Radiation Oncology
SchoolKeck School of Medicine of Usc
Address1441 Eastlake Ave.
Health Sciences Campus
Los Angeles CA 90033
ORCID ORCID Icon0000-0001-7586-9833 Additional info
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    Other Positions
    Title(s)DEI Champion for the Department of Radiation Oncology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Deconvolution of the tumor-educated platelet transcriptome reveals activated platelet and inflammatory cell transcript signatures. JCI Insight. 2024 Aug 27; 9(19). Karp JM, Modrek AS, Ezhilarasan R, Zhang ZY, Ding Y, Graciani M, Sahimi A, Silvestro M, Chen T, Li S, Wong KK, Ramkhelawon B, Bhat KP, Sulman EP. PMID: 39190500; PMCID: PMC11466191.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Lineage-coupled clonal capture identifies clonal evolution mechanisms and vulnerabilities of BRAFV600E inhibition resistance in melanoma. Cell Discov. 2022 Oct 06; 8(1):102. Zhang ZY, Ding Y, Ezhilarasan R, Lhakhang T, Wang Q, Yang J, Modrek AS, Zhang H, Tsirigos A, Futreal A, Draetta GF, Verhaak RGW, Sulman EP. PMID: 36202798; PMCID: PMC9537441.
      View in: PubMed   Mentions: 2  
    3. PDPN marks a subset of aggressive and radiation-resistant glioblastoma cells. Front Oncol. 2022; 12:941657. Modrek AS, Eskilsson E, Ezhilarasan R, Wang Q, Goodman LD, Ding Y, Zhang ZY, Bhat KPL, Le TT, Barthel FP, Tang M, Yang J, Long L, Gumin J, Lang FF, Verhaak RGW, Aldape KD, Sulman EP. PMID: 36059614; PMCID: PMC9434399.
      View in: PubMed   Mentions: 1  
    4. Pulmonary Toxic Effects After Myeloablative Conditioning With Total Body Irradiation Delivered via Volumetric Modulated Arc Therapy With Fludarabine. Pract Radiat Oncol. 2022 Nov-Dec; 12(6):e476-e480. Modrek AS, Karp JM, Byun D, Gerber NK, Abdul-Hay M, Al-Homsi AS, Galavis P, Teruel J, Yuan Y. PMID: 35598860.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Insight into the public's interest in tumour treating fields. Br J Cancer. 2021 09; 125(6):901-903. Byun DJ, Modrek AS, Sulman EP. PMID: 34316021; PMCID: PMC8437973.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Breaking Tradition to Bridge Bench and Bedside: Accelerating the MD-PhD-Residency Pathway. Acad Med. 2021 04 01; 96(4):518-521. Modrek AS, Tanese N, Placantonakis DG, Sulman EP, Rivera R, Du KL, Gerber NK, David G, Chesler M, Philips MR, Cangiarella J. PMID: 33464738.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Design and implementation of a clinical decision support tool for primary palliative Care for Emergency Medicine (PRIM-ER). BMC Med Inform Decis Mak. 2020 Jan 28; 20(1):13. Tan A, Durbin M, Chung FR, Rubin AL, Cuthel AM, McQuilkin JA, Modrek AS, Jamin C, Gavin N, Mann D, Swartz JL, Austrian JS, Testa PA, Hill JD, Grudzen CR, Group Authorship: Corita R. Grudzen on behalf of the PRIM-ER Clinical Informatics Advisory Board. PMID: 31992301; PMCID: PMC6988238.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    8. Mutant Isocitrate Dehydrogenase Inhibitors as Targeted Cancer Therapeutics. Front Oncol. 2019; 9:417. Golub D, Iyengar N, Dogra S, Wong T, Bready D, Tang K, Modrek AS, Placantonakis DG. PMID: 31165048; PMCID: PMC6534082.
      View in: PubMed   Mentions: 121  
    9. Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma. Sci Adv. 2018 10; 4(10):eaau5935. Stafford JM, Lee CH, Voigt P, Descostes N, Saldaña-Meyer R, Yu JR, Leroy G, Oksuz O, Chapman JR, Suarez F, Modrek AS, Bayin NS, Placantonakis DG, Karajannis MA, Snuderl M, Ueberheide B, Reinberg D. PMID: 30402543; PMCID: PMC6209383.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    10. Modeling Glioma with Human Embryonic Stem Cell-Derived Neural Lineages. Methods Mol Biol. 2018; 1741:227-237. Modrek AS, Prado J, Bready D, Dhaliwal J, Golub D, Placantonakis DG. PMID: 29392705.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    11. Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2. Cell Rep. 2017 Oct 31; 21(5):1267-1280. Modrek AS, Golub D, Khan T, Bready D, Prado J, Bowman C, Deng J, Zhang G, Rocha PP, Raviram R, Lazaris C, Stafford JM, LeRoy G, Kader M, Dhaliwal J, Bayin NS, Frenster JD, Serrano J, Chiriboga L, Baitalmal R, Nanjangud G, Chi AS, Golfinos JG, Wang J, Karajannis MA, Bonneau RA, Reinberg D, Tsirigos A, Zagzag D, Snuderl M, Skok JA, Neubert TA, Placantonakis DG. PMID: 29091765; PMCID: PMC5687844.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    12. Modeling HSV-1 Latency in Human Embryonic Stem Cell-Derived Neurons. Pathogens. 2017 Jun 08; 6(2). Pourchet A, Modrek AS, Placantonakis DG, Mohr I, Wilson AC. PMID: 28594343; PMCID: PMC5488658.
      View in: PubMed   Mentions: 28  
    13. Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells. Oncotarget. 2017 Sep 12; 8(39):64932-64953. Bayin NS, Frenster JD, Sen R, Si S, Modrek AS, Galifianakis N, Dolgalev I, Ortenzi V, Illa-Bochaca I, Khahera A, Serrano J, Chiriboga L, Zagzag D, Golfinos JG, Doyle W, Tsirigos A, Heguy A, Chesler M, Barcellos-Hoff MH, Snuderl M, Placantonakis DG. PMID: 29029402; PMCID: PMC5630302.
      View in: PubMed   Mentions: 37     Fields:    
    14. GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth. Oncogenesis. 2016 Oct 24; 5(10):e263. Bayin NS, Frenster JD, Kane JR, Rubenstein J, Modrek AS, Baitalmal R, Dolgalev I, Rudzenski K, Scarabottolo L, Crespi D, Redaelli L, Snuderl M, Golfinos JG, Doyle W, Pacione D, Parker EC, Chi AS, Heguy A, MacNeil DJ, Shohdy N, Zagzag D, Placantonakis DG. PMID: 27775701; PMCID: PMC5117849.
      View in: PubMed   Mentions: 29  
    15. Traumatic brain injury and subsequent glioblastoma development: Review of the literature and case reports. Surg Neurol Int. 2016; 7:78. Tyagi V, Theobald J, Barger J, Bustoros M, Bayin NS, Modrek AS, Kader M, Anderer EG, Donahue B, Fatterpekar G, Placantonakis DG. PMID: 27625888; PMCID: PMC5009580.
      View in: PubMed   Mentions: 18  
    16. Adult Primary Spinal Epidural Extraosseous Ewing's Sarcoma: A Case Report and Review of the Literature. Case Rep Neurol Med. 2016; 2016:1217428. Bustoros M, Thomas C, Frenster J, Modrek AS, Bayin NS, Snuderl M, Rosen G, Schiff PB, Placantonakis DG. PMID: 27610254; PMCID: PMC5005550.
      View in: PubMed   Mentions: 6  
    17. Preplanning prediction of the left anterior descending artery maximum dose based on patient, dosimetric, and treatment planning parameters. Adv Radiat Oncol. 2016 Oct-Dec; 1(4):373-381. Cooper BT, Li X, Shin SM, Modrek AS, Hsu HC, DeWyngaert JK, Jozsef G, Lymberis SC, Goldberg JD, Formenti SC. PMID: 28740908; PMCID: PMC5514165.
      View in: PubMed   Mentions: 5  
    18. Radiation therapy improves survival in rectal small cell cancer - Analysis of Surveillance Epidemiology and End Results (SEER) data. Radiat Oncol. 2015 Apr 24; 10:101. Modrek AS, Hsu HC, Leichman CG, Du KL. PMID: 25902707; PMCID: PMC4464878.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    19. Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells. PLoS One. 2014; 9(12):e116114. Bayin NS, Modrek AS, Dietrich A, Lebowitz J, Abel T, Song HR, Schober M, Zagzag D, Buchholz CJ, Chao MV, Placantonakis DG. PMID: 25541984; PMCID: PMC4277468.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    20. Glioblastoma stem cells: Molecular characteristics and therapeutic implications. World J Stem Cells. 2014 Apr 26; 6(2):230-8. Bayin NS, Modrek AS, Placantonakis DG. PMID: 24772249; PMCID: PMC3999780.
      View in: PubMed   Mentions: 35  
    21. Helicase SUV3, polynucleotide phosphorylase, and mitochondrial polyadenylation polymerase form a transient complex to modulate mitochondrial mRNA polyadenylated tail lengths in response to energetic changes. J Biol Chem. 2014 Jun 13; 289(24):16727-35. Wang DD, Guo XE, Modrek AS, Chen CF, Chen PL, Lee WH. PMID: 24770417; PMCID: PMC4059117.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    22. Brain stem cells as the cell of origin in glioma. World J Stem Cells. 2014 Jan 26; 6(1):43-52. Modrek AS, Bayin NS, Placantonakis DG. PMID: 24567787; PMCID: PMC3927013.
      View in: PubMed   Mentions: 44  
    23. Targeting tumor suppressor networks for cancer therapeutics. Curr Drug Targets. 2014 Jan; 15(1):2-16. Guo XE, Ngo B, Modrek AS, Lee WH. PMID: 24387338; PMCID: PMC4032821.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    24. Uncoupling the roles of the SUV3 helicase in maintenance of mitochondrial genome stability and RNA degradation. J Biol Chem. 2011 Nov 04; 286(44):38783-38794. Guo XE, Chen CF, Wang DD, Modrek AS, Phan VH, Lee WH, Chen PL. PMID: 21911497; PMCID: PMC3207411.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
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