Zhengzheng Xu, PhD

Title(s)Assistant Professor of Clinical Radiation Oncology
SchoolKeck School of Medicine of Usc
Address1441 Eastlake Ave.
Health Sciences Campus
Los Angeles CA 90033
ORCID ORCID Icon0000-0002-2893-8039 Additional info
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    Other Positions
    Title(s)Lead, Medical Physics LINAC Machine QA and QA Audits


    Collapse Biography 
    Collapse Education and Training
    Duke UniversityMS05/2012Medical Physics
    University at BuffaloPhD05/2016Medical Physics
    University Hospitals Seidman Cancer CenterResidency06/2018Medical Physics
    Collapse Awards and Honors
    AAPM Penn-Ohio Chapter2018AAPM Annual Meeting Travel Award of Penn-Ohio Chapter Meeting
    AAPM Upstate New York Chapter2016Young Investigator Competition -2nd
    Duke University2011Master Thesis Project Scholarship
    Zhejiang University2009  - 2010First-Class of National Scholarship Award
    Zhejiang University2009Top Student Dissertation Award

    Collapse Overview 
    Collapse Overview
    Dr. Zhengzheng Xu is an Assistant Professor of Clinical Radiation Oncology-Medical Physics at USC Norris Cancer Hospital and USC + Los Angeles County Medical Center. Dr. Xu joined USC in February 2021.

    Dr. Xu graduated from Zhejiang University in Zhejiang, China with a Bachelor of Science degree in Biomedical Engineering. He received his Master degree in Medical Physics from Duke University and the doctorate degree in Medical Physics from University at Buffalo. Dr. Xu completed his residency in medical physics at University Hospitals Seidman Cancer Center in 2018. After completing the residency, Dr. Xu became a clinical staff at UH Seidman Cancer Center specializing in medical physics. He was focused and dedicated in image guided radiotherapy (IGRT) for GI cancer and advanced HDR brachytherapy for GYN cancer.

    Dr. Xu has presented and published in multiple areas including HDR brachytherapy, stereotactic body radiation therapy(SBRT)/stereotactic radiosurgery(SRS), and FMEA for RadOnc. His research interests include image guided adaptive brachytherapy, SBRT/SRS and small field dosimetry.

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dosimetric characterization for GRID collimator-based spatially fractionated radiation therapy: Dosimetric parameter acquisition and machine interchangeability investigation. Journal of Applied Clinical Medical Physics. 2024; 25(8):1-11. Zhengzheng Xu, Salim Balik, Kaley Woods, Zhilei Shen, Chihyao Cheng, Jing Cui, Haihong Gallogly, Eric Chang, Lauren Lukas, Andrew Lim, Yutaka Natsuaki, Jason Ye, Lijun Ma, Hualin Zhang. View Publication.
    2. Hippocampal sparing radiation therapy for brain metastases: treatment techniques and clinical implementation. Chin Clin Oncol. 2023 Oct; 12(5):56. Woods K, Shen ZL, Xu Z, Zhang H, Natsuaki Y, Cheng K, Li V, Kim N, Ma L, Chang E. PMID: 37964545.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Dose uncertainty due to needle-tip localization error in prostate seed implantation. Journal of Contemporary Brachytherapy. 2022; 6(14):582-589. Zhengzheng Xu, Theodore H. Arsenault, Bryan Traughber, Roger Ove, Tarun K. Podder. View Publication.
    4. Automatic segmentation of high-risk clinical target volume for tandem-and-ovoids brachytherapy patients using an asymmetric dual-path convolutional neural network. Med Phys. 2022 Mar; 49(3):1712-1722. Cao Y, Vassantachart A, Ragab O, Bian S, Mitra P, Xu Z, Gallogly AZ, Cui J, Shen ZL, Balik S, Gribble M, Chang EL, Fan Z, Yang W. PMID: 35080018; PMCID: PMC9170543.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    5. Permanent Interstitial Cesium-131 Brachytherapy in Treating High-Risk Recurrent Head and Neck Cancer: A Prospective Pilot Study. Front Oncol. 2021; 11:639480. Kharouta M, Zender C, Podder T, Rezaee R, Lavertu P, Fowler N, Thuener J, Li S, Clancy K, Xu Z, Yao M. PMID: 33816283; PMCID: PMC8012839.
      View in: PubMed   Mentions: 3  
    6. Feasibility of improving patient's safety with in vivo dose tracking in intracavitary and interstitial HDR brachytherapy. Brachytherapy. 2021 Mar-Apr; 20(2):353-360. Muenkel J, Xu Z, Traughber BJ, Baig T, Xu K, Langmack C, Harris E, Podder TK. PMID: 33187822.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Appropriate Methodology for EBRT and HDR Intracavitary/Interstitial Brachytherapy Dose Composite and Clinical Plan Evaluation for Patients With Cervical Cancer. Pract Radiat Oncol. 2019 Nov; 9(6):e559-e571. Xu Z, Traughber BJ, Fredman E, Albani D, Ellis RJ, Podder TK. PMID: 31238167.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. Evaluating radiotherapy treatment delay using Failure Mode and Effects Analysis (FMEA). Radiother Oncol. 2019 08; 137:102-109. Xu Z, Lee S, Albani D, Dobbins D, Ellis RJ, Biswas T, Machtay M, Podder TK. PMID: 31082631.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    9. Assessment of beam-matched linacs quality/accuracy for interchanging SBRT or SRT patient using VMAT without replanning. J Appl Clin Med Phys. 2019 Jan; 20(1):68-75. Xu Z, Warrell G, Lee S, Colussi V, Zheng Y, Ellis R, Machtay M, Podder T. PMID: 30402983; PMCID: PMC6333115.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    10. Effects of collimator angle, couch angle, and starting phase on motion-tracking dynamic conformal arc therapy (4D DCAT). J Appl Clin Med Phys. 2017 Sep; 18(5):54-63. Xu Z, Yao R, Podgorsak MB, Wang IZ. PMID: 28730652; PMCID: PMC5874990.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Evaluation of dosimetric effect caused by slowing with multi-leaf collimator (MLC) leaves for volumetric modulated arc therapy (VMAT). Radiol Oncol. 2016 Feb 16; 50(1):121-128. Xu Z, Wang IZ, Kumaraswamy LK, Podgorsak MB. PMID: 32887199.
      View in: PubMed   Mentions:    Fields:    
    12. Evaluation of fluence-based dose delivery incorporating the spatial variation of dosimetric leaf gap (DLG). J Appl Clin Med Phys. 2016 01 08; 17(1):12-21. Kumaraswamy LK, Xu Z, Bailey DW, Schmitt JD, Podgorsak MB. PMID: 26894361; PMCID: PMC5690211.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    13. Spatial Variation of Dosimetric Leaf Gap and its Impact on Dose Delivery. Medical Physics. 2014; 11(41):111711. Kumaraswamy LK, JD Schmitt, DW Bailey, Z Xu, MB Podgorsak.
    14. Comparison of 125I and 103Pd isotopes in escalating dose to intraprostatic lesions for low dose rate prostate brachytherapy: dosimetry and acute toxicity. Journal of Oncology Research. 1(3):109. Muenkel, R Ellis, Z Xu, B Traughber, L Ponsky, T Podder.
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