Loading...

Zhang-Xu Liu, MD, PhD

Title(s)Assistant Professor of Research Medicine
AddressHMR 803
Health Sciences Campus
Los Angeles CA 90089-9091
Phone+1 323 442 3233
vCardDownload vCard

    Collapse Biography 
    Collapse Awards and Honors
    Japanese Government (Mobusho)1992  - 1997Fellowship
    Japanese Society of Gastroenterology1997Award
    American Digestive Health Foundation1999Travel Award

    Collapse Overview 
    Collapse Overview
    Dr. Liu's research interests include fucnation of liver NK and NKT cells, liver immunology and diseases, innate immunity in drug-induced hepatotoxicity, and immunity in alcoholic hepatitis. He is currently an Associate Editor of World Journal of Gastroenterology.

    Dr. Liu earned his medical degree from Chongqing Medical University. He then went on to complete his master's degree at Sichuan University West China Medical School, followed by a PhD from Tohoku University School of Medicine.

    Collapse Research 
    Collapse Research Activities and Funding
    Immunity in alcoholic hepatitis.
    NIH/NIAAA U01AA021857Sep 20, 2013 - Aug 31, 2018
    Role: Principal Investigator
    Liver innate immunity in drug-induced liver disease.
    NIH/NIDDK R01DK078586Jul 1, 2008 - Jun 30, 2014
    Role: Principal Investigator
    Liver innate immunity in drug-induced liver disease
    NIH/NIDDK K01DK067149Jul 1, 2004 - Jun 30, 2007
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mechanisms of adaptation and progression in idiosyncratic drug induced liver injury, clinical implications. Liver Int. 2016 Feb; 36(2):158-65. Dara L, Liu ZX, Kaplowitz N. PMID: 26484420.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    2. Targeting signal transduction pathways which regulate necrosis in acetaminophen hepatotoxicity. J Hepatol. 2015 Jul; 63(1):5-7. Kaplowitz N, Win S, Than TA, Liu ZX, Dara L. PMID: 25770661.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    3. Celecoxib attenuates hepatic cirrhosis through inhibition of epithelial-to-mesenchymal transition of hepatocytes. J Gastroenterol Hepatol. 2014 Nov; 29(11):1932-42. Wen SL, Gao JH, Yang WJ, Lu YY, Tong H, Huang ZY, Liu ZX, Tang CW. PMID: 24909904.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    4. Celecoxib ameliorates portal hypertension of the cirrhotic rats through the dual inhibitory effects on the intrahepatic fibrosis and angiogenesis. PLoS One. 2013; 8(7):e69309. Gao JH, Wen SL, Yang WJ, Lu YY, Tong H, Huang ZY, Liu ZX, Tang CW. PMID: 23922700.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    5. Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria. Trends Pharmacol Sci. 2013 Apr; 34(4):243-53. Han D, Dara L, Win S, Than TA, Yuan L, Abbasi SQ, Liu ZX, Kaplowitz N. PMID: 23453390.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    6. Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. Alcohol Clin Exp Res. 2011 Aug; 35(8):1509-18. Inokuchi S, Tsukamoto H, Park E, Liu ZX, Brenner DA, Seki E. PMID: 21463341.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    7. How to protect against acetaminophen: don't ask for JUNK. Gastroenterology. 2008 Oct; 135(4):1047-51. Kaplowitz N, Shinohara M, Liu ZX, Han D. PMID: 18782575.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    8. Role of innate immunity in acetaminophen-induced hepatotoxicity. Expert Opin Drug Metab Toxicol. 2006 Aug; 2(4):493-503. Liu ZX, Kaplowitz N. PMID: 16859400.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    9. c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity. Gastroenterology. 2006 Jul; 131(1):165-78. Gunawan BK, Liu ZX, Han D, Hanawa N, Gaarde WA, Kaplowitz N. PMID: 16831600.
      View in: PubMed   Mentions: 159     Fields:    Translation:AnimalsCells
    10. Neutrophil depletion protects against murine acetaminophen hepatotoxicity. Hepatology. 2006 Jun; 43(6):1220-30. Liu ZX, Han D, Gunawan B, Kaplowitz N. PMID: 16729305.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    11. Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity. Gastroenterology. 2004 Dec; 127(6):1760-74. Liu ZX, Govindarajan S, Kaplowitz N. PMID: 15578514.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    12. Activated natural killer T cells induce liver injury by Fas and tumor necrosis factor-alpha during alcohol consumption. Gastroenterology. 2004 May; 126(5):1387-99. Minagawa M, Deng Q, Liu ZX, Tsukamoto H, Dennert G. PMID: 15131799.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    13. IP-10 and Mig facilitate accumulation of T cells in the virus-infected liver. Cell Immunol. 2002 Sep; 219(1):48-56. Arai K, Liu ZX, Lane T, Dennert G. PMID: 12473267.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    14. Immune-mediated drug-induced liver disease. Clin Liver Dis. 2002 Aug; 6(3):755-74. Liu ZX, Kaplowitz N. PMID: 12362579.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    15. Hepatitis C virus genotype 1b core protein does not exert immunomodulatory effects on virus-induced cellular immunity. J Virol. 2002 Feb; 76(3):990-7. Liu ZX, Nishida H, He JW, Lai MM, Feng N, Dennert G. PMID: 11773374.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    Zhang-Xu's Networks
    Concepts (127)
    Derived automatically from this person's publications.
    _
    Co-Authors (10)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _