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Tracy C. Grikscheit, MD

Title(s)Professor of Surgery
AddressCHL Mail Stop 72
Off Campus
Los Angeles CA 90089
Phone+1 323 361 5901
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    Title(s)Division Chief of Pediatric Surgery in the Department of Surgery at CHLA


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    Dr. Grikscheit is a practicing pediatric surgeon and scientist with a laboratory focused on regenerative medicine and tissue engineering at in The Saban Research Institute at Children's Hospital Los Angeles. In the hospital, she cares for children who are born prematurely, and therefore are at increased risk for multiple medical conditions that may lead to intestinal lack or loss. One of these conditions is necrotizing enterocolitis (NEC), a potentially life-threatening intestinal problem. For the most severe cases of NEC, the only solution is surgical removal of the small intestine. However, this option leaves the baby dependent on intravenous feeding and the child is also at risk for liver damage from subsequent intravenous nutrition. Another option is small bowel transplantation, but graft and patient survival rates are still too low.

    Dr. Grikscheit, a member of The Saban Research Institute's Developmental Biology and Regenerative Medicine program, envisions a better solution. The small intestine is an exquisitely regenerative organ. It is an elegant model to better understand organ-specific stem cells and the regenerative cells can be harnessed to make new gastrointestinal tissue for eventual clinical applications. Understanding how to generate tissue-engineered intestines, whether esophagus, stomach, small intestine, or colon, may also inform us how to expand the list of organs that can be tissue-engineered.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. N-terminal deletion of specific phosphorylation sites on PHOX2B disrupts the formation of enteric neurons in vivo. Am J Physiol Gastrointest Liver Physiol. 2021 Apr 21. Chang DF, Gilliam EA, Nucho LA, Garcia J, Shevchenko Y, Zuber SM, Squillaro AI, Maselli KM, Huang S, Spence JR, Grikscheit TC. PMID: 33881351.
      View in: PubMed   Mentions:    Fields:    
    2. Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3ß-mediated restriction of epithelial IL-33. Nat Commun. 2021 02 05; 12(1):836. Schumacher MA, Hsieh JJ, Liu CY, Appel KL, Waddell A, Almohazey D, Katada K, Bernard JK, Bucar EB, Gadeock S, Maselli KM, Washington MK, Grikscheit TC, Warburton D, Rosen MJ, Frey MR. PMID: 33547321.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Regeneration and tissue engineering: How pediatric surgeons contributed to building a new field to change the future of medicine. Semin Pediatr Surg. 2021 Feb; 30(1):151018. De Coppi P, Grikscheit TC. PMID: 33648705.
      View in: PubMed   Mentions:    Fields:    
    4. R-Spondin1 enhances wnt signaling and decreases weight loss in short bowel syndrome zebrafish. Biochem Biophys Rep. 2021 Mar; 25:100874. Maselli KM, Levin G, Gee KM, Leeflang EJ, Carreira ACO, Sogayar MC, Grikscheit TC. PMID: 33437880.
      View in: PubMed   Mentions:
    5. A Purpose in Liquidity: Perfusing 3D Open Scaffolds Improves "Mini-gut" Morphogenesis and Longevity. Cell Stem Cell. 2020 Nov 05; 27(5):699-701. Schlieve CR, Grikscheit TC. PMID: 33157045.
      View in: PubMed   Mentions: 1     Fields:    
    6. Grading TESI: Crypt and villus formation in tissue-engineered small intestine alters with stem/progenitor cell source. Am J Physiol Gastrointest Liver Physiol. 2020 08 01; 319(2):G261-G279. Gilliam EA, Schlieve CR, Fowler KL, Rea JN, Schall KA, Huang S, Spence JR, Grikscheit TC. PMID: 32597710.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Broad-spectrum antibiotics alter the microbiome, increase intestinal fxr, and decrease hepatic steatosis in zebrafish short bowel syndrome. Am J Physiol Gastrointest Liver Physiol. 2020 08 01; 319(2):G212-G226. Maselli KM, Gee K, Isani M, Fode A, Schall KA, Grikscheit TC. PMID: 32597709.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. Thermal Injection Measurement (TIM) Adds Accuracy to Injections and Can Assess Cold Chain Management. J Surg Res. 2020 11; 255:261-266. Gilliam EA, Zuber SM, Grikscheit TC. PMID: 32570129.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    9. Remnant Intestinal Length Defines Intestinal Adaptation and Hepatic Steatosis: Two Zebrafish Models. J Surg Res. 2020 11; 255:86-95. Maselli KM, Gee K, Grikscheit TC. PMID: 32543383.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    10. R-Spondin 1 (RSPO1) Increases Mouse Intestinal Organoid Unit Size and Survival in vitro and Improves Tissue-Engineered Small Intestine Formation in vivo. Front Bioeng Biotechnol. 2020; 8:476. Levin G, Zuber SM, Squillaro AI, Sogayar MC, Grikscheit TC, Carreira ACO. PMID: 32582652.
      View in: PubMed   Mentions:
    11. Induced pluripotent stem cell-derived enteric neural crest cells repopulate human aganglionic tissue-engineered intestine to form key components of the enteric nervous system. J Tissue Eng. 2020 Jan-Dec; 11:2041731420905701. Chang DF, Zuber SM, Gilliam EA, Nucho LA, Levin G, Wang F, Squillaro AI, Huang S, Spence JR, Grikscheit TC. PMID: 32435442.
      View in: PubMed   Mentions:
    12. Spleen Organoid Units Generate Functional Human and Mouse Tissue-Engineered Spleen in a Murine Model. Tissue Eng Part A. 2020 04; 26(7-8):411-418. Gee K, Isani MA, Fode A, Maselli KM, Zuber SM, Fowler KL, Squillaro AI, Nucho LA, Grikscheit TC. PMID: 31696780.
      View in: PubMed   Mentions:    Fields:    
    13. Tissue-Engineering the Intestine: The Trials before the Trials. Cell Stem Cell. 2019 06 06; 24(6):855-859. Clevers H, Conder RK, Li VSW, Lutolf MP, Vallier L, Chan S, Grikscheit TC, Jensen KB, De Coppi P. PMID: 31173715.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    14. Wnt signaling inhibition by monensin results in a period of Hippo pathway activation during intestinal adaptation in zebrafish. Am J Physiol Gastrointest Liver Physiol. 2019 06 01; 316(6):G679-G691. Isani MA, Gee K, Schall K, Schlieve CR, Fode A, Fowler KL, Grikscheit TC. PMID: 30896968.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    15. Differential epithelial growth in tissue-engineered larynx and trachea generated from postnatal and fetal progenitor cells. Biochem Biophys Res Commun. 2019 03 05; 510(2):205-210. Knaneh-Monem H, Thornton ME, Grubbs BH, Warburton D, Grikscheit TC, Hochstim C. PMID: 30691694.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    16. Short-term and long-term human or mouse organoid units generate tissue-engineered small intestine without added signalling molecules. Exp Physiol. 2018 12; 103(12):1633-1644. Hou X, Chang DF, Trecartin A, Barthel ER, Schlieve CR, Frey MR, Fowler KL, Grikscheit TC. PMID: 30232817.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    17. Stem cells for babies and their surgeons: The future is now. J Pediatr Surg. 2019 Jan; 54(1):16-20. Zuber SM, Grikscheit TC. PMID: 30497818.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    18. Corrigendum to "Inhibition of Fgf signaling in short bowel syndrome increases weight loss and epithelial proliferation." [surgery volume 161, number 3 (2017) 694-703]. Surgery. 2018 06; 163(6):1330-1331. Schall KA, Holoyda KA, Isani M, Lien CL, Alam DA, Grikscheit TC. PMID: 29452701.
      View in: PubMed   Mentions:    Fields:    
    19. Tissue Engineering Functional Gastrointestinal Regions: The Importance of Stem and Progenitor Cells. Cold Spring Harb Perspect Med. 2017 Oct 03; 7(10). Trecartin A, Grikscheit T. PMID: 28320829.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    20. Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine. Stem Cell Reports. 2017 09 12; 9(3):883-896. Schlieve CR, Fowler KL, Thornton M, Huang S, Hajjali I, Hou X, Grubbs B, Spence JR, Grikscheit TC. PMID: 28803915.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    21. Marked stem/progenitor cell expansion occurs early after murine ileostomy: a new model. J Surg Res. 2017 12; 220:182-196. Fowler KL, Wieck MM, Hilton AE, Hou X, Schlieve CR, Grikscheit TC. PMID: 29180181.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    22. Fibroblast Growth Factors in the Gastrointestinal Tract: Twists and Turns. Dev Dyn. 2017 04; 246(4):344-352. Danopoulos S, Schlieve CR, Grikscheit TC, Al Alam D. PMID: 28198118.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    23. Short bowel syndrome results in increased gene expression associated with proliferation, inflammation, bile acid synthesis and immune system activation: RNA sequencing a zebrafish SBS model. BMC Genomics. 2017 01 25; 18(1):23. Schall KA, Thornton ME, Isani M, Holoyda KA, Hou X, Lien CL, Grubbs BH, Grikscheit TC. PMID: 28118819.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    24. Prolonged Absence of Mechanoluminal Stimulation in Human Intestine Alters the Transcriptome and Intestinal Stem Cell Niche. Cell Mol Gastroenterol Hepatol. 2017 May; 3(3):367-388.e1. Wieck MM, Schlieve CR, Thornton ME, Fowler KL, Isani M, Grant CN, Hilton AE, Hou X, Grubbs BH, Frey MR, Grikscheit TC. PMID: 28462379.
      View in: PubMed   Mentions: 3     Fields:    
    25. Created of Warm Blood and Nerves: Restoring an Enteric Nervous System in Organoids. Cell Stem Cell. 2017 01 05; 20(1):5-7. Schlieve CR, Grikscheit TC. PMID: 28061353.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Intestinal adaptation in proximal and distal segments: Two epithelial responses diverge after intestinal separation. Surgery. 2017 04; 161(4):1016-1027. Schall KA, Holoyda KA, Isani M, Schlieve C, Salisbury T, Khuu T, Debelius JW, Moats RA, Pollack HA, Lien CL, Fowler K, Hou X, Knight R, Grikscheit TC. PMID: 28011012.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    27. Establishing Proximal and Distal Regional Identities in Murine and Human Tissue-Engineered Lung and Trachea. Tissue Eng Part C Methods. 2016 11; 22(11):1049-1057. Trecartin A, Danopoulos S, Spurrier R, Knaneh-Monem H, Hiatt M, Driscoll B, Hochstim C, Al-Alam D, Grikscheit TC. PMID: 27796199.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    28. Inhibition of Fgf signaling in short bowel syndrome increases weight loss and epithelial proliferation. Surgery. 2017 03; 161(3):694-703. Schall KA, Holoyda KA, Isani M, Lien CL, Al Alam D, Grikscheit TC. PMID: 27771159.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    29. Functional Human and Murine Tissue-Engineered Liver Is Generated from Adult Stem/Progenitor Cells. Stem Cells Transl Med. 2017 01; 6(1):238-248. Mavila N, Trecartin A, Spurrier R, Xiao Y, Hou X, James D, Fu X, Truong B, Wang C, Lipshutz GS, Wang KS, Grikscheit TC. PMID: 28170183.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    30. The pediatric intestinal mucosal microbiome remains altered after clinical resolution of inflammatory and ischemic disease. Surgery. 2016 08; 160(2):350-8. Wieck MM, Debelius JW, Spurrier RG, Trecartin A, Knight R, Grikscheit TC. PMID: 27302104.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. Vascular Endothelial Growth Factor (VEGF) Bioavailability Regulates Angiogenesis and Intestinal Stem and Progenitor Cell Proliferation during Postnatal Small Intestinal Development. PLoS One. 2016; 11(3):e0151396. Schlieve CR, Mojica SG, Holoyda KA, Hou X, Fowler KL, Grikscheit TC. PMID: 26978773.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    32. Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease. Nature. 2016 Mar 03; 531(7592):105-9. Fattahi F, Steinbeck JA, Kriks S, Tchieu J, Zimmer B, Kishinevsky S, Zeltner N, Mica Y, El-Nachef W, Zhao H, de Stanchina E, Gershon MD, Grikscheit TC, Chen S, Studer L. PMID: 26863197.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    33. Sequestration of Vascular Endothelial Growth Factor (VEGF) Induces Late Restrictive Lung Disease. PLoS One. 2016; 11(2):e0148323. Wieck MM, Spurrier RG, Levin DE, Mojica SG, Hiatt MJ, Reddy R, Hou X, Navarro S, Lee J, Lundin A, Driscoll B, Grikscheit TC. PMID: 26863115.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    34. Human and Murine Tissue-Engineered Colon Exhibit Diverse Neuronal Subtypes and Can Be Populated by Enteric Nervous System Progenitor Cells When Donor Colon Is Aganglionic. Tissue Eng Part A. 2016 Jan; 22(1-2):53-64. Wieck MM, El-Nachef WN, Hou X, Spurrier RG, Holoyda KA, Schall KA, Mojica SG, Collins MK, Trecartin A, Cheng Z, Frykman PK, Grikscheit TC. PMID: 26414777.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    35. Generation of tissue-engineered small intestine using embryonic stem cell-derived human intestinal organoids. Biol Open. 2015 Oct 12; 4(11):1462-72. Finkbeiner SR, Freeman JJ, Wieck MM, El-Nachef W, Altheim CH, Tsai YH, Huang S, Dyal R, White ES, Grikscheit TC, Teitelbaum DH, Spence JR. PMID: 26459240.
      View in: PubMed   Mentions:
    36. Adult zebrafish intestine resection: a novel model of short bowel syndrome, adaptation, and intestinal stem cell regeneration. Am J Physiol Gastrointest Liver Physiol. 2015 Aug 01; 309(3):G135-45. Schall KA, Holoyda KA, Grant CN, Levin DE, Torres ER, Maxwell A, Pollack HA, Moats RA, Frey MR, Darehzereshki A, Al Alam D, Lien C, Grikscheit TC. PMID: 26089336.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    37. Fibroblast growth factor 10 alters the balance between goblet and Paneth cells in the adult mouse small intestine. Am J Physiol Gastrointest Liver Physiol. 2015 Apr 15; 308(8):G678-90. Al Alam D, Danopoulos S, Schall K, Sala FG, Almohazey D, Fernandez GE, Georgia S, Frey MR, Ford HR, Grikscheit T, Bellusci S. PMID: 25721301.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    38. Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential. Cell. 2015 Jan 15; 160(1-2):269-84. Worthley DL, Churchill M, Compton JT, Tailor Y, Rao M, Si Y, Levin D, Schwartz MG, Uygur A, Hayakawa Y, Gross S, Renz BW, Setlik W, Martinez AN, Chen X, Nizami S, Lee HG, Kang HP, Caldwell JM, Asfaha S, Westphalen CB, Graham T, Jin G, Nagar K, Wang H, Kheirbek MA, Kolhe A, Carpenter J, Glaire M, Nair A, Renders S, Manieri N, Muthupalani S, Fox JG, Reichert M, Giraud AS, Schwabe RF, Pradere JP, Walton K, Prakash A, Gumucio D, Rustgi AK, Stappenbeck TS, Friedman RA, Gershon MD, Sims P, Grikscheit T, Lee FY, Karsenty G, Mukherjee S, Wang TC. PMID: 25594183.
      View in: PubMed   Mentions: 183     Fields:    Translation:AnimalsCells
    39. Human and mouse tissue-engineered small intestine both demonstrate digestive and absorptive function. Am J Physiol Gastrointest Liver Physiol. 2015 Apr 15; 308(8):G664-77. Grant CN, Mojica SG, Sala FG, Hill JR, Levin DE, Speer AL, Barthel ER, Shimada H, Zachos NC, Grikscheit TC. PMID: 25573173.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    40. Murine and human tissue-engineered esophagus form from sufficient stem/progenitor cells and do not require microdesigned biomaterials. Tissue Eng Part A. 2015 Mar; 21(5-6):906-15. Spurrier RG, Speer AL, Hou X, El-Nachef WN, Grikscheit TC. PMID: 25298083.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    41. Stem cells and biopharmaceuticals: vital roles in the growth of tissue-engineered small intestine. Semin Pediatr Surg. 2014 Jun; 23(3):141-9. Belchior GG, Sogayar MC, Grikscheit TC. PMID: 24994528.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    42. Enteric nervous system cell replacement therapy for Hirschsprung disease: beyond tissue-engineered intestine. Eur J Pediatr Surg. 2014 Jun; 24(3):214-8. El-Nachef W, Grikscheit T. PMID: 24870947.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    43. Vitrification preserves murine and human donor cells for generation of tissue-engineered intestine. J Surg Res. 2014 Aug; 190(2):399-406. Spurrier RG, Speer AL, Grant CN, Levin DE, Grikscheit TC. PMID: 24857678.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    44. Regenerative medicine: is this the biggest change in surgery? Semin Pediatr Surg. 2014 Jun; 23(3):103-5. De Coppi P, Grikscheit TC. PMID: 24994522.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. Delayed family reunification of pediatric disaster survivors increases mortality and inpatient hospital costs: a simulation study. J Surg Res. 2013 Sep; 184(1):430-7. Barthel ER, Pierce JR, Speer AL, Levin DE, Goodhue CJ, Ford HR, Grikscheit TC, Upperman JS. PMID: 23827792.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    46. Tissue engineering: a promising therapeutic approach to necrotizing enterocolitis. Semin Pediatr Surg. 2013 May; 22(2):112-6. Grant CN, Grikscheit TC. PMID: 23611615.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    47. Fgf10 overexpression enhances the formation of tissue-engineered small intestine. J Tissue Eng Regen Med. 2016 Feb; 10(2):132-9. Torashima Y, Levin DE, Barthel ER, Speer AL, Sala FG, Hou X, Grikscheit TC. PMID: 23468377.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    48. Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats. Addict Biol. 2013 Sep; 18(5):786-99. Aarde SM, Angrish D, Barlow DJ, Wright MJ, Vandewater SA, Creehan KM, Houseknecht KL, Dickerson TJ, Taffe MA. PMID: 23380001.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    49. Human tissue-engineered small intestine forms from postnatal progenitor cells. J Pediatr Surg. 2013 Jan; 48(1):129-37. Levin DE, Barthel ER, Speer AL, Sala FG, Hou X, Torashima Y, Grikscheit TC. PMID: 23331805.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    50. A "living bioreactor" for the production of tissue-engineered small intestine. Methods Mol Biol. 2013; 1001:299-309. Levin DE, Sala FG, Barthel ER, Speer AL, Hou X, Torashima Y, Grikscheit TC. PMID: 23494439.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    51. Forearm skeletal muscle neuroblastoma in a child: a rare primary location. J Pediatr Hematol Oncol. 2013 Jan; 35(1):61-3. Giuliani S, Marachelian A, Franklin A, Shimada H, Grikscheit T. PMID: 23249961.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    52. Tissue engineering of the intestine in a murine model. J Vis Exp. 2012 Dec 01; (70):e4279. Barthel ER, Speer AL, Levin DE, Sala FG, Hou X, Torashima Y, Wigfall CM, Grikscheit TC. PMID: 23222891.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    53. Intraoperative hypercyanosis in a patient with pulmonary artery band: case report and review of the literature. J Clin Anesth. 2012 Dec; 24(8):652-5. Pierce JR, Sharma SS, Hunter CJ, Bhombal S, Fagan B, Corchado Y, Grikscheit TC, Bushman GA. PMID: 23164642.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis. PLoS One. 2012; 7(11):e49127. Speer AL, Al Alam D, Sala FG, Ford HR, Bellusci S, Grikscheit TC. PMID: 23133671.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    55. Human tissue-engineered colon forms from postnatal progenitor cells: an in vivo murine model. Regen Med. 2012 Nov; 7(6):807-18. Barthel ER, Levin DE, Speer AL, Sala FG, Torashima Y, Hou X, Grikscheit TC. PMID: 23164081.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    56. Giant cystic meconium peritonitis presenting in a neonate with classic radiographic eggshell calcifications and treated with an elective surgical approach: a case report. J Med Case Rep. 2012 Aug 02; 6:229. Barthel ER, Speer AL, Levin DE, Naik-Mathuria BJ, Grikscheit TC. PMID: 22857611.
      View in: PubMed   Mentions: 1     Fields:    
    57. FGF9-Pitx2-FGF10 signaling controls cecal formation in mice. Dev Biol. 2012 Sep 15; 369(2):340-8. Al Alam D, Sala FG, Baptista S, Galzote R, Danopoulos S, Tiozzo C, Gage P, Grikscheit T, Warburton D, Frey MR, Bellusci S. PMID: 22819677.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    58. Solid pseudopapillary tumor of the pancreas: a single-institution 20-year series of pediatric patients. J Pediatr Surg. 2012 Jun; 47(6):1217-22. Speer AL, Barthel ER, Patel MM, Grikscheit TC. PMID: 22703796.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    59. Tissue-engineering of the gastrointestinal tract. Curr Opin Pediatr. 2012 Jun; 24(3):365-70. Levin DE, Grikscheit TC. PMID: 22450251.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    60. Treatment of congenital pulmonary airway malformation induced hydrops fetalis via percutaneous sclerotherapy. Fetal Diagn Ther. 2012; 31(4):264-8. Lee FL, Said N, Grikscheit TC, Shin CE, Llanes A, Chmait RH. PMID: 22354268.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    61. Tissue-engineered small intestine. Expert Rev Med Devices. 2011 Nov; 8(6):673-5. Levin DE, Dreyfuss JM, Grikscheit TC. PMID: 22029464.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    62. Availability of a pediatric trauma center in a disaster surge decreases triage time of the pediatric surge population: a population kinetics model. Theor Biol Med Model. 2011 Oct 12; 8:38. Barthel ER, Pierce JR, Goodhue CJ, Ford HR, Grikscheit TC, Upperman JS. PMID: 21992575.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    63. VEGF optimizes the formation of tissue-engineered small intestine. Regen Med. 2011 Sep; 6(5):559-67. Matthews JA, Sala FG, Speer AL, Warburton D, Grikscheit TC. PMID: 21916592.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    64. Mesenchymal-specific inhibition of vascular endothelial growth factor (VEGF) attenuates growth in neonatal mice. J Surg Res. 2012 Jan; 172(1):40-7. Matthews JA, Sala FG, Speer AL, Li Y, Warburton D, Grikscheit TC. PMID: 21696760.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    65. A multicellular approach forms a significant amount of tissue-engineered small intestine in the mouse. Tissue Eng Part A. 2011 Jul; 17(13-14):1841-50. Sala FG, Matthews JA, Speer AL, Torashima Y, Barthel ER, Grikscheit TC. PMID: 21395443.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    66. Murine tissue-engineered stomach demonstrates epithelial differentiation. J Surg Res. 2011 Nov; 171(1):6-14. Speer AL, Sala FG, Matthews JA, Grikscheit TC. PMID: 21571313.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    67. FGF10 controls the patterning of the tracheal cartilage rings via Shh. Development. 2011 Jan; 138(2):273-82. Sala FG, Del Moral PM, Tiozzo C, Alam DA, Warburton D, Grikscheit T, Veltmaat JM, Bellusci S. PMID: 21148187.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    68. Massive subcutaneous emphysema, pneumomediastinum, and pneumopericardium in children. J Pediatr Surg. 2010 Mar; 45(3):647-9. Giuliani S, Franklin A, Pierce J, Ford H, Grikscheit TC. PMID: 20223337.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    69. Wnt5a knock-out mouse as a new model of anorectal malformation. J Surg Res. 2009 Oct; 156(2):278-82. Tai CC, Sala FG, Ford HR, Wang KS, Li C, Minoo P, Grikscheit TC, Bellusci S. PMID: 19577771.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    70. Tissue-engineered small intestine and stomach form from autologous tissue in a preclinical large animal model. J Surg Res. 2009 Oct; 156(2):205-12. Sala FG, Kunisaki SM, Ochoa ER, Vacanti J, Grikscheit TC. PMID: 19665143.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    71. Thoracoscopic repair of neonatal diaphragmatic hernia. J Laparoendosc Adv Surg Tech A. 2008 Dec; 18(6):875-80. Guner YS, Chokshi N, Aranda A, Ochoa C, Qureshi FG, Nguyen NX, Grikscheit T, Ford HR, Stein JE, Shin CE. PMID: 19105674.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    72. Preservation of extracorporeal tissue in closing gastroschisis augments intestinal length. J Pediatr Surg. 2008 Dec; 43(12):2213-5. Estrada JJ, Petrosyan M, Hunter CJ, Lee SL, Anselmo DM, Grikscheit TC, Stein JE, Wang KS, Ford HR, Shaul DB. PMID: 19040937.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    73. Necrotizing enterocolitis--bench to bedside: novel and emerging strategies. Semin Pediatr Surg. 2008 Nov; 17(4):255-65. Guner YS, Chokshi N, Petrosyan M, Upperman JS, Ford HR, Grikscheit TC. PMID: 19019294.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    74. Tissue-engineered spleen protects against overwhelming pneumococcal sepsis in a rodent model. J Surg Res. 2008 Oct; 149(2):214-8. Grikscheit TC, Sala FG, Ogilvie J, Bower KA, Ochoa ER, Alsberg E, Mooney D, Vacanti JP. PMID: 18621401.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    75. Cost considerations and applicant characteristics for the Pediatric Surgery Match. J Pediatr Surg. 2005 Jan; 40(1):69-73; discussion 73-4. Little DC, Yoder SM, Grikscheit TC, Jackson CC, Fuchs JR, McCrudden KW, Holcomb GW. PMID: 15868561.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    76. Tissue-engineered small intestine improves recovery after massive small bowel resection. Ann Surg. 2004 Nov; 240(5):748-54. Grikscheit TC, Siddique A, Ochoa ER, Srinivasan A, Alsberg E, Hodin RA, Vacanti JP. PMID: 15492554.
      View in: PubMed   Mentions: 65     Fields:    Translation:Animals
    77. Lymphangiogenesis in tissue-engineered small intestine. Transplantation. 2004 Apr 27; 77(8):1162-6. Duxbury MS, Grikscheit TC, Gardner-Thorpe J, Rocha FG, Ito H, Perez A, Ashley SW, Vacanti JP, Whang EE. PMID: 15114078.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    78. Angiogenesis in tissue-engineered small intestine. Tissue Eng. 2003 Dec; 9(6):1255-61. Gardner-Thorpe J, Grikscheit TC, Ito H, Perez A, Ashley SW, Vacanti JP, Whang EE. PMID: 14670113.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    79. Tissue-engineered stomach: a preliminary report of a versatile in vivo model with therapeutic potential. J Pediatr Surg. 2003 Sep; 38(9):1305-9. Grikscheit T, Srinivasan A, Vacanti JP. PMID: 14523810.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    80. Effect of GLP-2 on mucosal morphology and SGLT1 expression in tissue-engineered neointestine. Am J Physiol Gastrointest Liver Physiol. 2003 Dec; 285(6):G1345-52. Ramsanahie A, Duxbury MS, Grikscheit TC, Perez A, Rhoads DB, Gardner-Thorpe J, Ogilvie J, Ashley SW, Vacanti JP, Whang EE. PMID: 12919941.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    81. Tissue engineering of the gastrointestinal tract for surgical replacement: a nutrition tool of the future? Proc Nutr Soc. 2003 Aug; 62(3):739-43. Grikscheit TC. PMID: 14692609.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    82. Tissue-engineered esophagus: experimental substitution by onlay patch or interposition. J Thorac Cardiovasc Surg. 2003 Aug; 126(2):537-44. Grikscheit T, Ochoa ER, Srinivasan A, Gaissert H, Vacanti JP. PMID: 12928655.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    83. Tissue-engineered large intestine resembles native colon with appropriate in vitro physiology and architecture. Ann Surg. 2003 Jul; 238(1):35-41. Grikscheit TC, Ochoa ER, Ramsanahie A, Alsberg E, Mooney D, Whang EE, Vacanti JP. PMID: 12832963.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    84. Tissue-engineered small intestine: ontogeny of the immune system. Transplantation. 2002 Sep 15; 74(5):619-23. Perez A, Grikscheit TC, Blumberg RS, Ashley SW, Vacanti JP, Whang EE. PMID: 12352876.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    85. Tissue-engineered colon exhibits function in vivo. Surgery. 2002 Aug; 132(2):200-4. Grikscheit TC, Ogilvie JB, Ochoa ER, Alsberg E, Mooney D, Vacanti JP. PMID: 12219012.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    86. The history and current status of tissue engineering: The future of pediatric surgery. J Pediatr Surg. 2002 Mar; 37(3):277-88. Grikscheit TC, Vacanti JP. PMID: 11877635.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    87. A novel tumor-derived mediator that sensitizes cytokine-resistant tumors to tumor necrosis factor. J Surg Res. 1996 Jun; 63(1):248-55. Marvin MR, Libutti SK, Kayton M, Kao J, Hayward J, Grikscheit T, Fan Y, Brett J, Weinberg A, Nowygrod R, LoGerfo P, Feind C, Hansen KS, Schwartz M, Stern D, Chabot J. PMID: 8661206.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    88. Characterization of a novel tumor-derived cytokine. Endothelial-monocyte activating polypeptide II. J Biol Chem. 1994 Oct 07; 269(40):25106-19. Kao J, Houck K, Fan Y, Haehnel I, Libutti SK, Kayton ML, Grikscheit T, Chabot J, Nowygrod R, Greenberg S. PMID: 7929199.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
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