Loading...
Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Todd E. Morgan, PhD

    TitleResearch Professor of Gerontology
    SchoolSchool of Gerontology
    DepartmentGerontology
    AddressGER 327
    University Park Campus
    Los Angeles California 90089-0191
    Phone+1 213 740 4083
    vCardDownload vCard

      Collapse Overview 
      Collapse Overview
      Todd Morgan, Ph.D. is a Research Associate Professor of Gerontology at the University of Southern California. In 1984, he received his B.S. in Chemistry at Dana College in Blair, Nebraska. He then studied at Colorado State University for his Ph.D. in Biochemistry and at USC for his Post-Doctorate in Neurobiology.

      Professor Morgan has been awarded the “Glial Aging & Inflammatory Mechanisms in AD” Pilot Award at USC’s Alzheimer’s Disease Research Center and the “CR & Inflammatory Mechanisms in AD” Temple Award, the “Regulation of Complement Expression” Turken Award, and the “Clusterin Regulation & Activity During Neurodegeneration” Faculty Scholar Award at the Alzheimer’s Association.


      Collapse ORNG Applications 
      Collapse Websites
      Collapse In The News

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Wei M, Brandhorst S, Shelehchi M, Mirzaei H, Cheng CW, Budniak J, Groshen S, Mack WJ, Guen E, Di Biase S, Cohen P, Morgan T, Dorff T, Hong K, Michalsen A, Laviano A, Longo VD. Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease. Sci Transl Med. 2017 Feb 15; 9(377). PMID: 28202779.
        View in: PubMed
      2. Lee AS, Brandhorst S, Rangel DF, Navarrete G, Cohen P, Longo VD, Chen J, Groshen S, Morgan T, Dubeau L. Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice. Sci Rep. 2017 Feb 01; 7:40919. PMID: 28145503.
        View in: PubMed
      3. Woodward NC, Pakbin P, Saffari A, Shirmohammadi F, Haghani A, Sioutas C, Cacciottolo M, Morgan T, Finch CE. Traffic-related air pollution impact on mouse brain accelerates myelin and neuritic aging changes with specificity for CA1 neurons. Neurobiol Aging. 2017 Jan 13; 53:48-58. PMID: 28212893.
        View in: PubMed
      4. Choi IY, Piccio L, Childress P, Bollman B, Ghosh A, Brandhorst S, Suarez J, Michalsen A, Cross AH, Morgan T, Wei M, Paul F, Bock M, Longo VD. A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms. Cell Rep. 2016 Jun 7; 15(10):2136-46. PMID: 27239035.
        View in: PubMed
      5. Cheng H, Saffari A, Sioutas C, Forman HJ, Morgan T, Finch CE. Nanoscale Particulate Matter from Urban Traffic Rapidly Induces Oxidative Stress and Inflammation in Olfactory Epithelium with Concomitant Effects on Brain. Environ Health Perspect. 2016 Oct; 124(10):1537-1546. PMID: 27187980.
        View in: PubMed
      6. Liu Q, Babadjouni R, Radwanski R, Cheng H, Patel A, Hodis DM, He S, Baumbacher P, Russin JJ, Morgan T, Sioutas C, Finch CE, Mack WJ. Stroke Damage Is Exacerbated by Nano-Size Particulate Matter in a Mouse Model. PLoS One. 2016; 11(4):e0153376. PMID: 27071057.
        View in: PubMed
      7. Cheng H, Davis DA, Hasheminassab S, Sioutas C, Morgan T, Finch CE. Urban traffic-derived nanoparticulate matter reduces neurite outgrowth via TNFa in vitro. J Neuroinflammation. 2016; 13(1):19. PMID: 26810976.
        View in: PubMed
      8. Cacciottolo M, Christensen A, Moser A, Liu J, Pike CJ, Smith C, LaDu MJ, Sullivan PM, Morgan T, Dolzhenko E, Charidimou A, Wahlund LO, Wiberg MK, Shams S, Chiang GC. The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice. Neurobiol Aging. 2016 Jan; 37:47-57. PMID: 26686669.
        View in: PubMed
      9. Morgan T, Finch CE. Astrocytic estrogen receptors and impaired neurotrophic responses in a rat model of perimenopause. Front Aging Neurosci. 2015; 7:179. PMID: 26483679.
        View in: PubMed
      10. Wright TT, Jimenez RV, Morgan T, Bali N, Hou X, McCrory MA, Finch CE, Szalai AJ. Hepatic but Not CNS-Expressed Human C-Reactive Protein Inhibits Experimental Autoimmune Encephalomyelitis in Transgenic Mice. Autoimmune Dis. 2015; 2015:640171. PMID: 26421184.
        View in: PubMed
      11. Brandhorst S, Choi IY, Wei M, Cheng CW, Sedrakyan S, Navarrete G, Dubeau L, Yap LP, Park R, Vinciguerra M, Di Biase S, Mirzaei H, Mirisola MG, Childress P, Ji L, Groshen S, Penna F, Odetti P, Perin L, Conti PS, Ikeno Y, Kennedy BK, Cohen P, Morgan T, Dorff TB, Longo VD. A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan. Cell Metab. 2015 Jul 7; 22(1):86-99. PMID: 26094889.
        View in: PubMed
      12. Woodward N, Finch CE, Morgan T. Traffic-related air pollution and brain development. AIMS Environ Sci. 2015; 2(2):353-373. PMID: 27099868.
        View in: PubMed
      13. Yin F, Yao J, Sancheti H, Feng T, Melcangi RC, Morgan T, Finch CE, Pike CJ, Mack WJ, Cadenas E, Brinton RD. The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity. Neurobiol Aging. 2015 Jul; 36(7):2282-95. PMID: 25921624.
        View in: PubMed
      14. Barron AM, Brown MA, Morgan T, Pike CJ. Impact of continuous versus discontinuous progesterone on estradiol regulation of neuron viability and sprouting after entorhinal cortex lesion in female rats. Endocrinology. 2015 Mar; 156(3):1091-9. PMID: 25514084.
        View in: PubMed
      15. Davis DA, Akopian G, Walsh JP, Sioutas C, Morgan T, Finch CE. Urban air pollutants reduce synaptic function of CA1 neurons via an NMDA/N? pathway in vitro. J Neurochem. 2013 Nov; 127(4):509-19. PMID: 23927064.
        View in: PubMed
      16. Davis DA, Bortolato M, Godar SC, Sander TK, Iwata N, Pakbin P, Shih JC, Berhane K, McConnell R, Sioutas C, Finch CE, Morgan T. Prenatal exposure to urban air nanoparticles in mice causes altered neuronal differentiation and depression-like responses. PLoS One. 2013; 8(5):e64128. PMID: 23734187.
        View in: PubMed
      17. Li R, Navab M, Pakbin P, Ning Z, Navab K, Hough G, Morgan T, Finch CE, Araujo JA, Fogelman AM, Sioutas C, Hsiai T. Ambient Ultrafine Particles Alter Lipid Metabolism and HDL Anti-Oxidant Capacity in LDLR-null Mice. J Lipid Res. 2013 Apr 6. PMID: 23564731.
        View in: PubMed
      18. Arimoto JM, Wong A, Rozovsky I, Lin SW, Morgan T, Finch CE. Age increase of estrogen receptor-a (ERa) in cortical astrocytes impairs neurotrophic support in male and female rats. Endocrinology. 2013 Jun; 154(6):2101-13. PMID: 23515288.
        View in: PubMed
      19. Brandhorst S, Wei M, Hwang S, Morgan T, Longo VD. Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression. Exp Gerontol. 2013 Oct; 48(10):1120-8. PMID: 23454633.
        View in: PubMed
      20. Chepelev NL, Zhang H, Liu H, McBride S, Seal AJ, Morgan T, Finch CE, Willmore WG, Davies KJ, Forman HJ. Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction. Redox Biol. 2013; 1(1):183-9. PMID: 24024152.
        View in: PubMed
      21. Pfaffenbach KT, Pong M, Morgan T, Wang H, Ott K, Zhou B, Longo VD, Lee AS. GRP78/BiP is a novel downstream target of IGF-1 receptor mediated signaling. J Cell Physiol. 2012 Dec; 227(12):3803-11. PMID: 22422508.
        View in: PubMed
      22. Jayaraman A, Carroll JC, Morgan T, Lin S, Zhao L, Arimoto JM, Murphy MP, Beckett TL, Finch CE, Brinton RD, Pike CJ. 17ß-Estradiol and Progesterone Regulate Expression of ß-Amyloid Clearance Factors in Primary Neuron Cultures and Female Rat Brain. Endocrinology. 2012 Nov; 153(11):5467-79. PMID: 22962256.
        View in: PubMed
      23. Zhang H, Liu H, Davies KJ, Sioutas C, Finch CE, Morgan T, Forman HJ. Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments. Free Radic Biol Med. 2012 May 1; 52(9):2038-46. PMID: 22401859.
        View in: PubMed
      24. Zhao L, Morgan T, Mao Z, Lin S, Cadenas E, Finch CE, Pike CJ, Mack WJ, Brinton RD. Continuous versus Cyclic Progesterone Exposure Differentially Regulates Hippocampal Gene Expression and Functional Profiles. PLoS One. 2012; 7(2):e31267. PMID: 22393359.
        View in: PubMed
      25. Simmons MS, Artal R, Burch MA, Cain RP, Campano R, Cohen HG, Mann CA, Morgan T, Owens JA, Pullinger A, Relle R, Roesler JM, Sotos J, Yagiela JA, Ziman RB, Simmons JH. Dentistry-based approaches to sleep-disordered breathing, algorithms, and multidisciplinary perspectives. J Calif Dent Assoc. 2012 Feb; 40(2):168-81. PMID: 22416636.
        View in: PubMed
      26. Kremsky I, Morgan T, Hou X, Li L, Finch CE. Age-changes in gene expression in primary mixed glia cultures from young vs. old rat cerebral cortex are modified by interactions with neurons. Brain Behav Immun. 2012 Jul; 26(5):797-802. PMID: 22226781.
        View in: PubMed
      27. Bali N, Arimoto JM, Iwata N, Lin SW, Zhao L, Brinton RD, Morgan T, Finch CE. Differential Responses of Progesterone Receptor Membrane Component-1 (Pgrmc1) and the Classical Progesterone Receptor (Pgr) to 17ß-Estradiol and Progesterone in Hippocampal Subregions that Support Synaptic Remodeling and Neurogenesis. Endocrinology. 2012 Feb; 153(2):759-69. PMID: 22147012.
        View in: PubMed
      28. Morgan T, Davis DA, Iwata N, Tanner JA, Snyder D, Ning Z, Kam W, Hsu YT, Winkler JW, Chen JC, Petasis NA, Baudry M, Sioutas C, Finch CE. Glutamatergic neurons in rodent models respond to nanoscale particulate urban air pollutants in vivo and in vitro. Environ Health Perspect. 2011 Jul; 119(7):1003-9. PMID: 21724521.
        View in: PubMed
      29. Finch CE, Morgan T, Longo VD, de Magalhaes JP. Cell resilience in species life spans: a link to inflammation? Aging Cell. 2010 Aug; 9(4):519-26. PMID: 20415721.
        View in: PubMed
      30. Nunez-Iglesias J, Liu CC, Morgan T, Finch CE, Zhou XJ. Joint genome-wide profiling of miRNA and mRNA expression in Alzheimer's disease cortex reveals altered miRNA regulation. PLoS One. 2010; 5(2):e8898. PMID: 20126538.
        View in: PubMed
      31. Wong AM, Rozovsky I, Arimoto JM, Du Y, Wei M, Morgan T, Finch CE. Progesterone influence on neurite outgrowth involves microglia. Endocrinology. 2009 Jan; 150(1):324-32. PMID: 18772232.
        View in: PubMed
      32. Faghihi MA, Modarresi F, Khalil AM, Wood DE, Sahagan BG, Morgan T, Finch CE, St Laurent G, Kenny PJ, Wahlestedt C. Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nat Med. 2008 Jul; 14(7):723-30. PMID: 18587408.
        View in: PubMed
      33. Brinton RD, Thompson RF, Foy MR, Baudry M, Wang J, Finch CE, Morgan T, Pike CJ, Mack WJ, Stanczyk FZ, Nilsen J. Progesterone receptors: form and function in brain. Front Neuroendocrinol. 2008 May; 29(2):313-39. PMID: 18374402.
        View in: PubMed
      34. Finch CE, Morgan T. Systemic inflammation, infection, ApoE alleles, and Alzheimer disease: a position paper. Curr Alzheimer Res. 2007 Apr; 4(2):185-9. PMID: 17430245.
        View in: PubMed
      35. Morgan T, Wong AM, Finch CE. Anti-inflammatory mechanisms of dietary restriction in slowing aging processes. Interdiscip Top Gerontol. 2007; 35:83-97. PMID: 17063034.
        View in: PubMed
      36. Wong AM, Patel NV, Patel NK, Wei M, Morgan T, de Beer MC, de Villiers WJ, Finch CE. Macrosialin increases during normal brain aging are attenuated by caloric restriction. Neurosci Lett. 2005 Dec 23; 390(2):76-80. PMID: 16157452.
        View in: PubMed
      37. Rozovsky I, Wei M, Morgan T, Finch CE. Reversible age impairments in neurite outgrowth by manipulations of astrocytic GFAP. Neurobiol Aging. 2005 May; 26(5):705-15. PMID: 15708446.
        View in: PubMed
      38. Zhou XJ, Kao MC, Huang H, Wong A, Nunez-Iglesias J, Primig M, Aparicio OM, Finch CE, Morgan T, Wong WH. Functional annotation and network reconstruction through cross-platform integration of microarray data. Nat Biotechnol. 2005 Feb; 23(2):238-43. PMID: 15654329.
        View in: PubMed
      39. Patel NV, Gordon MN, Connor KE, Good RA, Engelman RW, Mason J, Morgan DG, Morgan T, Finch CE. Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models. Neurobiol Aging. 2005 Jul; 26(7):995-1000. PMID: 15748777.
        View in: PubMed
      40. Patel NV, Wei M, Wong A, Finch CE, Morgan T. Progressive changes in regulation of apolipoproteins E and J in glial cultures during postnatal development and aging. Neurosci Lett. 2004 Nov 23; 371(2-3):199-204. PMID: 15519757.
        View in: PubMed
      41. Wilhelmsson U, Li L, Pekna M, Berthold CH, Blom S, Eliasson C, Renner O, Bushong E, Ellisman M, Morgan T, Pekny M. Absence of glial fibrillary acidic protein and vimentin prevents hypertrophy of astrocytic processes and improves post-traumatic regeneration. J Neurosci. 2004 May 26; 24(21):5016-21. PMID: 15163694.
        View in: PubMed
      42. Xie Z, Morgan T, Rozovsky I, Finch CE. Aging and glial responses to lipopolysaccharide in vitro: greater induction of IL-1 and IL-6, but smaller induction of neurotoxicity. Exp Neurol. 2003 Jul; 182(1):135-41. PMID: 12821383.
        View in: PubMed
      43. Xie Z, Wei M, Morgan T, Fabrizio P, Han D, Finch CE, Longo VD. Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia. J Neurosci. 2002 May 1; 22(9):3484-92. PMID: 11978825.
        View in: PubMed
      44. Rozovsky I, Wei M, Stone DJ, Zanjani H, Anderson CP, Morgan T, Finch CE. Estradiol (E2) enhances neurite outgrowth by repressing glial fibrillary acidic protein expression and reorganizing laminin. Endocrinology. 2002 Feb; 143(2):636-46. PMID: 11796520.
        View in: PubMed
      45. Morgan T, Rozovsky I, Sarkar DK, Young-Chan CS, Nichols NR, Laping NJ, Finch CE. Transforming growth factor-beta1 induces transforming growth factor-beta1 and transforming growth factor-beta receptor messenger RNAs and reduces complement C1qB messenger RNA in rat brain microglia. Neuroscience. 2000; 101(2):313-21. PMID: 11074155.
        View in: PubMed
      Todd's Networks
      Concepts
      Derived automatically from this person's publications.
      _
      Co-Authors
      People in Profiles who have published with this person.
      _
      Similar People
      People who share similar concepts with this person.
      _
      Same Department