Shou-Jiang Gao, PhD

TitleProfessor of Molecular Microbiology & Immunology
InstitutionUniversity of Southern California
DepartmentMolecular Microbiology and Immunology
AddressNRT 5501 1450 Biggy Street
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 442 8028
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    KSHV microRNAs in tumor invasion and angiogenesis
    NIH/NCI R01CA213275Mar 3, 2017 - Feb 28, 2022
    Role: Principal Investigator
    NIH/NIDCR R01DE025465Jul 10, 2015 - Apr 30, 2020
    Role: Principal Investigator
    Targeting KSHV malignancies and persistent infection
    NIH/NCI R01CA197153May 1, 2015 - Apr 30, 2020
    Role: Principal Investigator
    KSHV microRNAs in cellular transformation and tumorigenesis
    NIH/NCI R01CA177377Sep 1, 2013 - Aug 31, 2016
    Role: Principal Investigator
    Mechanism of KSHV-induced angiogenesis
    NIH/NCI R01CA132637Dec 1, 2007 - Mar 31, 2021
    Role: Principal Investigator
    Regulation of KSHV infection and replication by MAPK pathways
    NIH/NCI R01CA124332Jul 1, 2006 - Mar 31, 2018
    Role: Principal Investigator
    Role of Epstein-Barr virus LMP1 in lymphoma
    NIH/NCI R01CA106159Jun 17, 2005 - May 31, 2012
    Role: Principal Investigator
    Cell model for KSHV infection and genetic manipulation
    NIH/NCI R01CA096512Apr 1, 2002 - Feb 28, 2022
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Required Scholarly Project Mentor

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Gruffaz M, Zhou S, Vasan K, Rushing T, Michael QL, Lu C, Jung JU, Gao S. Repurposing Cytarabine for Treating Primary Effusion Lymphoma by Targeting Kaposi's Sarcoma-Associated Herpesvirus Latent and Lytic Replications. MBio. 2018 May 08; 9(3). PMID: 29739902.
      View in: PubMed
    2. Tan B, Gao S. RNA epitranscriptomics: Regulation of infection of RNA and DNA viruses by N6 -methyladenosine (m6 A). Rev Med Virol. 2018 Apr 26; e1983. PMID: 29698584.
      View in: PubMed
    3. Cheng F, Ramos da Silva S, Huang IC, Jung JU, Gao S. Suppression of Zika Virus Infection and Replication in Endothelial Cells and Astrocytes by PKA Inhibitor PKI 14-22. J Virol. 2018 02 15; 92(4). PMID: 29212931.
      View in: PubMed
    4. Liang Q, Wei D, Chung B, Brulois KF, Guo C, Dong S, Gao S, Feng P, Liang C, Jung JU. Novel Role of vBcl2 in the Virion Assembly of Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 2018 02 15; 92(4). PMID: 29167347.
      View in: PubMed
    5. Lee HR, Li F, Choi UY, Yu HR, Aldrovandi GM, Feng P, Gao S, Hong YK, Jung JU. Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. MBio. 2018 Jan 16; 9(1). PMID: 29339432.
      View in: PubMed
    6. Liu H, Wang H, Wei Z, Zhang S, Hua G, Zhang SW, Zhang L, Gao S, Meng J, Chen X, Huang Y. MeT-DB V2.0: elucidating context-specific functions of N6-methyl-adenosine methyltranscriptome. Nucleic Acids Res. 2018 Jan 04; 46(D1):D281-D287. PMID: 29126312.
      View in: PubMed
    7. Tan B, Liu H, Zhang S, da Silva SR, Zhang L, Meng J, Cui X, Yuan H, Sorel O, Zhang SW, Huang Y, Gao S. Viral and cellular N6-methyladenosine and N6,2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan; 3(1):108-120. PMID: 29109479.
      View in: PubMed
    8. Gruffaz M, Vasan K, Tan B, Ramos da Silva S, Gao S. TLR4-Mediated Inflammation Promotes KSHV-Induced Cellular Transformation and Tumorigenesis by Activating the STAT3 Pathway. Cancer Res. 2017 12 15; 77(24):7094-7108. PMID: 29051178.
      View in: PubMed
    9. Jeon H, Yoo SM, Choi HS, Mun JY, Kang HG, Lee J, Park J, Gao S, Lee MS. Extracellular vesicles from KSHV-infected endothelial cells activate the complement system. Oncotarget. 2017 Nov 21; 8(59):99841-99860. PMID: 29245944.
      View in: PubMed
    10. Zhu Y, Li T, Ramos da Silva S, Lee JJ, Lu C, Eoh H, Jung JU, Gao S. A Critical Role of Glutamine and Asparagine ?-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus. MBio. 2017 08 15; 8(4). PMID: 28811348.
      View in: PubMed
    11. He M, Tan B, Vasan K, Yuan H, Cheng F, Ramos da Silva S, Lu C, Gao S. SIRT1 and AMPK pathways are essential for the proliferation and survival of primary effusion lymphoma cells. J Pathol. 2017 Jul; 242(3):309-321. PMID: 28393364.
      View in: PubMed
    12. Qin J, Li W, Gao S, Lu C. KSHV microRNAs: Tricks of the Devil. Trends Microbiol. 2017 08; 25(8):648-661. PMID: 28259385.
      View in: PubMed
    13. Yuan H, He M, Cheng F, Bai R, da Silva SR, Aguiar RC, Gao S. Tenovin-6 inhibits proliferation and survival of diffuse large B-cell lymphoma cells by blocking autophagy. Oncotarget. 2017 Feb 28; 8(9):14912-14924. PMID: 28118604.
      View in: PubMed
    14. Yuan H, Tan B, Gao S. Tenovin-6 impairs autophagy by inhibiting autophagic flux. Cell Death Dis. 2017 02 09; 8(2):e2608. PMID: 28182004.
      View in: PubMed
    15. Ma X, Zhu Y, Huang Y, Tegeler T, Gao S, Zhang J. Quantitative Proteomic Approach for MicroRNA Target Prediction Based on 18O/16O Labeling. Cancer Inform. 2015; 14(Suppl 5):163-173. PMID: 27980386.
      View in: PubMed
    16. He M, Yuan H, Tan B, Bai R, Kim HS, Bae S, Che L, Kim JS, Gao S. SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells. Oncotarget. 2016 11 15; 7(46):75698-75711. PMID: 27708228.
      View in: PubMed
    17. Yan Q, Shen C, Qin J, Li W, Hu M, Lu H, Qin D, Zhu J, Gao S, Lu C. HIV-1 Vpr Inhibits Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by Inducing MicroRNA miR-942-5p and Activating NF-?B Signaling. J Virol. 2016 10 01; 90(19):8739-53. PMID: 27440900; PMCID: PMC5021437 [Available on 03/12/17].
    18. Toth Z, Papp B, Brulois K, Choi YJ, Gao S, Jung JU. LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection. PLoS Pathog. 2016 Sep; 12(9):e1005878. PMID: 27606464; PMCID: PMC5015872.
    19. Ye F, Zeng Y, Sha J, Jones T, Kuhne K, Wood C, Gao S. High Glucose Induces Reactivation of Latent Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 2016 Aug 17. PMID: 27535045.
      View in: PubMed
    20. Cheng F, He M, Jung JU, Lu C, Gao S. Suppression of Kaposi's Sarcoma-Associated Herpesvirus Infection and Replication by 5'-AMP-Activated Protein Kinase. J Virol. 2016 07 15; 90(14):6515-6525. PMID: 27147746.
      View in: PubMed
    21. Li W, Jia X, Shen C, Zhang M, Xu J, Shang Y, Zhu K, Hu M, Yan Q, Qin D, Lee MS, Zhu J, Lu H, Krueger BJ, Renne R, Gao S, Lu C. A KSHV microRNA enhances viral latency and induces angiogenesis by targeting GRK2 to activate the CXCR2/AKT pathway. Oncotarget. 2016 May 31; 7(22):32286-305. PMID: 27058419.
      View in: PubMed
    22. Ramos da Silva S, Gao S. Zika virus update II: Recent development of animal models-Proofs of association with human pathogenesis. J Med Virol. 2016 10; 88(10):1657-8. PMID: 27208545.
      View in: PubMed
    23. Zhu Y, Ramos da Silva S, He M, Liang Q, Lu C, Feng P, Jung JU, Gao S. An Oncogenic Virus Promotes Cell Survival and Cellular Transformation by Suppressing Glycolysis. PLoS Pathog. 2016 May; 12(5):e1005648. PMID: 27187079; PMCID: PMC4871371.
    24. Ramos da Silva S, Gao S. Zika virus: An update on epidemiology, pathology, molecular biology, and animal model. J Med Virol. 2016 08; 88(8):1291-6. PMID: 27124623.
      View in: PubMed
    25. Li W, Yan Q, Ding X, Shen C, Hu M, Zhu Y, Qin D, Lu H, Krueger BJ, Renne R, Gao S, Lu C. The SH3BGR/STAT3 Pathway Regulates Cell Migration and Angiogenesis Induced by a Gammaherpesvirus MicroRNA. PLoS Pathog. 2016 04; 12(4):e1005605. PMID: 27128969.
      View in: PubMed
    26. Lee MS, Yuan H, Jeon H, Zhu Y, Yoo S, Shi S, Krueger B, Renne R, Lu C, Jung JU, Gao S. Human Mesenchymal Stem Cells of Diverse Origins Support Persistent Infection with Kaposi's Sarcoma-Associated Herpesvirus and Manifest Distinct Angiogenic, Invasive, and Transforming Phenotypes. MBio. 2016 Jan 26; 7(1):e02109-15. PMID: 26814175; PMCID: PMC4742711.
    27. Bowman J, Rodgers MA, Shi M, Amatya R, Hostager B, Iwai K, Gao S, Jung JU. Posttranslational Modification of HOIP Blocks Toll-Like Receptor 4-Mediated Linear-Ubiquitin-Chain Formation. MBio. 2015 Nov 17; 6(6):e01777-15. PMID: 26578682; PMCID: PMC4659476.
    28. Lee HR, Mitra J, Lee S, Gao S, Oh TK, Kim MH, Ha T, Jung JU. Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 4 (vIRF4) Perturbs the G1-S Cell Cycle Progression via Deregulation of the cyclin D1 Gene. J Virol. 2016 01 15; 90(2):1139-43. PMID: 26491150.
      View in: PubMed
    29. Yao S, Hu M, Hao T, Li W, Xue X, Xue M, Zhu X, Zhou F, Qin D, Yan Q, Zhu J, Gao S, Lu C. MiRNA-891a-5p mediates HIV-1 Tat and KSHV Orf-K1 synergistic induction of angiogenesis by activating NF-?B signaling. Nucleic Acids Res. 2015 Oct 30; 43(19):9362-78. PMID: 26446987; PMCID: PMC4627096.
    30. Hu M, Wang C, Li W, Lu W, Bai Z, Qin D, Yan Q, Zhu J, Krueger BJ, Renne R, Gao S, Lu C. A KSHV microRNA Directly Targets G Protein-Coupled Receptor Kinase 2 to Promote the Migration and Invasion of Endothelial Cells by Inducing CXCR2 and Activating AKT Signaling. PLoS Pathog. 2015 Sep; 11(9):e1005171. PMID: 26402907; PMCID: PMC4581863.
    31. Cheng F, Sawant TV, Lan K, Lu C, Jung JU, Gao S. Screening of the Human Kinome Identifies MSK1/2-CREB1 as an Essential Pathway Mediating Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication during Primary Infection. J Virol. 2015 Sep; 89(18):9262-80. PMID: 26109721; PMCID: PMC4542378.
    32. Zhang J, Zhu L, Lu X, Feldman ER, Keyes LR, Wang Y, Fan H, Feng H, Xia Z, Sun J, Jiang T, Gao S, Tibbetts SA, Feng P. Recombinant Murine Gamma Herpesvirus 68 Carrying KSHV G Protein-Coupled Receptor Induces Angiogenic Lesions in Mice. PLoS Pathog. 2015 Jun; 11(6):e1005001. PMID: 26107716; PMCID: PMC4479558.
    33. Brulois K, Wong LY, Lee HR, Sivadas P, Ensser A, Feng P, Gao S, Toth Z, Jung JU. Association of Kaposi's Sarcoma-Associated Herpesvirus ORF31 with ORF34 and ORF24 Is Critical for Late Gene Expression. J Virol. 2015 Jun; 89(11):6148-54. PMID: 25810551; PMCID: PMC4442431.
    34. Lee MS, Jones T, Song DY, Jang JH, Jung JU, Gao S. Exploitation of the complement system by oncogenic Kaposi's sarcoma-associated herpesvirus for cell survival and persistent infection. PLoS Pathog. 2014 Sep; 10(9):e1004412. PMID: 25254972; PMCID: PMC4177982.
    35. Xue M, Yao S, Hu M, Li W, Hao T, Zhou F, Zhu X, Lu H, Qin D, Yan Q, Zhu J, Gao S, Lu C. HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway. Nucleic Acids Res. 2014 Sep; 42(15):9862-79. PMID: 25104021; PMCID: PMC4150761.
    36. Liang D, Hu H, Li S, Dong J, Wang X, Wang Y, He L, He Z, Gao Y, Gao S, Lan K. Oncogenic herpesvirus KSHV Hijacks BMP-Smad1-Id signaling to promote tumorigenesis. PLoS Pathog. 2014 Jul; 10(7):e1004253. PMID: 25010525; PMCID: PMC4092152.
    37. Brulois K, Toth Z, Wong LY, Feng P, Gao S, Ensser A, Jung JU. Kaposi's sarcoma-associated herpesvirus K3 and K5 ubiquitin E3 ligases have stage-specific immune evasion roles during lytic replication. J Virol. 2014 Aug; 88(16):9335-49. PMID: 24899205; PMCID: PMC4136276.
    38. Zhu Y, Huang Y, Jung JU, Lu C, Gao S. Viral miRNA targeting of bicistronic and polycistronic transcripts. Curr Opin Virol. 2014 Aug; 7:66-72. PMID: 24821460; PMCID: PMC4149931.
    39. Li Q, He M, Zhou F, Ye F, Gao S. Activation of Kaposi's sarcoma-associated herpesvirus (KSHV) by inhibitors of class III histone deacetylases: identification of sirtuin 1 as a regulator of the KSHV life cycle. J Virol. 2014 Jun; 88(11):6355-67. PMID: 24672028; PMCID: PMC4093851.
    40. Yan Q, Ma X, Shen C, Cao X, Feng N, Qin D, Zeng Y, Zhu J, Gao S, Lu C. Inhibition of Kaposi's sarcoma-associated herpesvirus lytic replication by HIV-1 Nef and cellular microRNA hsa-miR-1258. J Virol. 2014 May; 88(9):4987-5000. PMID: 24554664; PMCID: PMC3993842.
    41. Jones T, Ramos da Silva S, Bedolla R, Ye F, Zhou F, Gao S. Viral cyclin promotes KSHV-induced cellular transformation and tumorigenesis by overriding contact inhibition. Cell Cycle. 2014; 13(5):845-58. PMID: 24419204; PMCID: PMC3979920.
    42. He M, Gao S. A novel role of SIRT1 in gammaherpesvirus latency and replication. Cell Cycle. 2014; 13(21):3328-30. PMID: 25485577; PMCID: PMC4614076.
    43. Moody R, Zhu Y, Huang Y, Cui X, Jones T, Bedolla R, Lei X, Bai Z, Gao S. KSHV microRNAs mediate cellular transformation and tumorigenesis by redundantly targeting cell growth and survival pathways. PLoS Pathog. 2013; 9(12):e1003857. PMID: 24385912; PMCID: PMC3873467.
    44. Bai Z, Huang Y, Li W, Zhu Y, Jung JU, Lu C, Gao S. Genomewide mapping and screening of Kaposi's sarcoma-associated herpesvirus (KSHV) 3' untranslated regions identify bicistronic and polycistronic viral transcripts as frequent targets of KSHV microRNAs. J Virol. 2014 Jan; 88(1):377-92. PMID: 24155407; PMCID: PMC3911756.
    45. Cui J, Petritis K, Tegeler T, Petritis B, Ma X, Jin Y, Gao S, Zhang JM. Accurate LC peak boundary detection for ¹6O/¹8O labeled LC-MS data. PLoS One. 2013; 8(10):e72951. PMID: 24115998; PMCID: PMC3792097.
    46. Wong LY, Brulois K, Toth Z, Inn KS, Lee SH, O'Brien K, Lee H, Gao S, Cesarman E, Ensser A, Jung JU. The product of Kaposi's sarcoma-associated herpesvirus immediate early gene K4.2 regulates immunoglobulin secretion and calcium homeostasis by interacting with and inhibiting pERP1. J Virol. 2013 Nov; 87(22):12069-79. PMID: 23986581; PMCID: PMC3807884.
    47. Zhu Y, Haecker I, Yang Y, Gao S, Renne R. ?-Herpesvirus-encoded miRNAs and their roles in viral biology and pathogenesis. Curr Opin Virol. 2013 Jun; 3(3):266-75. PMID: 23743127; PMCID: PMC3879080.
    48. Ye FC, Zhou FC, Nithianantham S, Chandran B, Yu XL, Weinberg A, Gao S. Kaposi's sarcoma-associated herpesvirus induces rapid release of angiopoietin-2 from endothelial cells. J Virol. 2013 Jun; 87(11):6326-35. PMID: 23536671; PMCID: PMC3648120.
    49. Zhou F, Xue M, Qin D, Zhu X, Wang C, Zhu J, Hao T, Cheng L, Chen X, Bai Z, Feng N, Gao S, Lu C. HIV-1 Tat promotes Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6-induced angiogenesis and tumorigenesis by regulating PI3K/PTEN/AKT/GSK-3ß signaling pathway. PLoS One. 2013; 8(1):e53145. PMID: 23301033; PMCID: PMC3534639.
    50. Zhang W, Gao S. Exploitation of Cellular Cytoskeletons and Signaling Pathways for Cell Entry by Kaposi's Sarcoma-Associated Herpesvirus and the Closely Related Rhesus Rhadinovirus. Pathogens. 2012 Dec; 1(2):102-27. PMID: 23420076; PMCID: PMC3571711.
    51. Lei X, Zhu Y, Jones T, Bai Z, Huang Y, Gao S. A Kaposi's sarcoma-associated herpesvirus microRNA and its variants target the transforming growth factor ß pathway to promote cell survival. J Virol. 2012 Nov; 86(21):11698-711. PMID: 22915806; PMCID: PMC3486299.
    52. Fu B, Yang R, Xia F, Li B, Ouyang X, Gao S, Wang L. Gender differences in Kaposi's sarcoma-associated herpesvirus infection in a population with schistosomiasis in rural China. Jpn J Infect Dis. 2012 Jul; 65(4):350-3. PMID: 22814163; PMCID: PMC3513380.
    53. Brulois KF, Chang H, Lee AS, Ensser A, Wong LY, Toth Z, Lee SH, Lee HR, Myoung J, Ganem D, Oh TK, Kim JF, Gao S, Jung JU. Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome clone. J Virol. 2012 Sep; 86(18):9708-20. PMID: 22740391; PMCID: PMC3446615.
    54. Greene W, Zhang W, He M, Witt C, Ye F, Gao S. The ubiquitin/proteasome system mediates entry and endosomal trafficking of Kaposi's sarcoma-associated herpesvirus in endothelial cells. PLoS Pathog. 2012; 8(5):e1002703. PMID: 22615563; PMCID: PMC3355089.
    55. He M, Zhang W, Bakken T, Schutten M, Toth Z, Jung JU, Gill P, Cannon M, Gao S. Cancer angiogenesis induced by Kaposi sarcoma-associated herpesvirus is mediated by EZH2. Cancer Res. 2012 Jul 15; 72(14):3582-92. PMID: 22593192; PMCID: PMC4034471.
    56. Jones T, Ye F, Bedolla R, Huang Y, Meng J, Qian L, Pan H, Zhou F, Moody R, Wagner B, Arar M, Gao S. Direct and efficient cellular transformation of primary rat mesenchymal precursor cells by KSHV. J Clin Invest. 2012 Mar; 122(3):1076-81. PMID: 22293176; PMCID: PMC3287217.
    57. Bai Z, Zhou F, Lei X, Ma X, Lu C, Gao S. A cluster of transcripts encoded by KSHV ORF30-33 gene locus. Virus Genes. 2012 Apr; 44(2):225-36. PMID: 22180077; PMCID: PMC3290719.
    58. Zhang W, Greene W, Gao S. Microtubule- and dynein-dependent nuclear trafficking of rhesus rhadinovirus in rhesus fibroblasts. J Virol. 2012 Jan; 86(1):599-604. PMID: 22031929; PMCID: PMC3255885.
    59. Ye F, Gao S. A novel role of hydrogen peroxide in Kaposi sarcoma-associated herpesvirus reactivation. Cell Cycle. 2011 Oct 01; 10(19):3237-8. PMID: 21941083; PMCID: PMC3233619.
    60. Ye F, Zhou F, Bedolla RG, Jones T, Lei X, Kang T, Guadalupe M, Gao S. Reactive oxygen species hydrogen peroxide mediates Kaposi's sarcoma-associated herpesvirus reactivation from latency. PLoS Pathog. 2011 May; 7(5):e1002054. PMID: 21625536; PMCID: PMC3098240.
    61. Zhou F, Gao S. Recent advances in cloning herpesviral genomes as infectious bacterial artificial chromosomes. Cell Cycle. 2011 Feb 01; 10(3):434-40. PMID: 21245660; PMCID: PMC3115017.
    62. Ye F, Lei X, Gao S. Mechanisms of Kaposi's Sarcoma-Associated Herpesvirus Latency and Reactivation. Adv Virol. 2011; 2011. PMID: 21625290.
      View in: PubMed
    63. Guadalupe M, Pollock BH, Westbrook S, Redding S, Bullock D, Anstead G, Agan BK, Marconi VC, Barbieri S, Sankar V, Rebeles J, Flahive Y, Schoolfield J, Wang L, Lei X, Dow D, Yeh CK, Dang H, Infante AJ, Gao S. Risk factors influencing antibody responses to Kaposi's sarcoma-associated herpesvirus latent and lytic antigens in patients under antiretroviral therapy. J Acquir Immune Defic Syndr. 2011 Jan 01; 56(1):83-90. PMID: 21084997; PMCID: PMC3051282.
    64. Liu H, Yue D, Zhang L, Chen Y, Gao S, Huang Y. A Bayesian approach for identifying miRNA targets by combining sequence prediction and gene expression profiling. BMC Genomics. 2010 Dec 01; 11 Suppl 3:S12. PMID: 21143779; PMCID: PMC2999342.
    65. Meng J, Lu M, Chen Y, Gao S, Huang Y. Robust inference of the context specific structure and temporal dynamics of gene regulatory network. BMC Genomics. 2010 Dec 01; 11 Suppl 3:S11. PMID: 21143778; PMCID: PMC2999341.
    66. Liu H, Yue D, Chen Y, Gao S, Huang Y. Improving performance of mammalian microRNA target prediction. BMC Bioinformatics. 2010 Sep 22; 11:476. PMID: 20860840; PMCID: PMC2955701.
    67. Zhang W, Zhou F, Greene W, Gao S. Rhesus rhadinovirus infection of rhesus fibroblasts occurs through clathrin-mediated endocytosis. J Virol. 2010 Nov; 84(22):11709-17. PMID: 20826690; PMCID: PMC2977882.
    68. Lei X, Bai Z, Ye F, Huang Y, Gao S. Regulation of herpesvirus lifecycle by viral microRNAs. Virulence. 2010 Sep-Oct; 1(5):433-5. PMID: 21170300; PMCID: PMC3003333.
    69. Lei X, Bai Z, Ye F, Huang Y, Gao S. MicroRNAs control herpesviral dormancy. Cell Cycle. 2010 Apr 01; 9(7):1225-6. PMID: 20234183; PMCID: PMC2910125.
    70. Lei X, Bai Z, Ye F, Xie J, Kim CG, Huang Y, Gao S. Regulation of NF-kappaB inhibitor IkappaBalpha and viral replication by a KSHV microRNA. Nat Cell Biol. 2010 Feb; 12(2):193-9. PMID: 20081837; PMCID: PMC2815189.
    71. Zhou F, Li Q, Wong SW, Gao S. Autoexcision of bacterial artificial chromosome facilitated by terminal repeat-mediated homologous recombination: a novel approach for generating traceless genetic mutants of herpesviruses. J Virol. 2010 Mar; 84(6):2871-80. PMID: 20071577; PMCID: PMC2826046.
    72. Lee JS, Li Q, Lee JY, Lee SH, Jeong JH, Lee HR, Chang H, Zhou FC, Gao S, Liang C, Jung JU. FLIP-mediated autophagy regulation in cell death control. Nat Cell Biol. 2009 Nov; 11(11):1355-62. PMID: 19838173; PMCID: PMC2802862.
    73. Fu B, Sun F, Li B, Yang L, Zeng Y, Sun X, Xu F, Rayner S, Guadalupe M, Gao S, Wang L. Seroprevalence of Kaposi's sarcoma-associated herpesvirus and risk factors in Xinjiang, China. J Med Virol. 2009 Aug; 81(8):1422-31. PMID: 19551832; PMCID: PMC2755560.
    74. Greene W, Gao S. Actin dynamics regulate multiple endosomal steps during Kaposi's sarcoma-associated herpesvirus entry and trafficking in endothelial cells. PLoS Pathog. 2009 Jul; 5(7):e1000512. PMID: 19593382; PMCID: PMC2702172.
    75. Meng J, Gao S, Huang Y. Enrichment constrained time-dependent clustering analysis for finding meaningful temporal transcription modules. Bioinformatics. 2009 Jun 15; 25(12):1521-7. PMID: 19351618; PMCID: PMC2687989.
    76. Chen J, Ye F, Xie J, Kuhne K, Gao S. Genome-wide identification of binding sites for Kaposi's sarcoma-associated herpesvirus lytic switch protein, RTA. Virology. 2009 Apr 10; 386(2):290-302. PMID: 19233445; PMCID: PMC2663009.
    77. Liu H, Gao S, Huang Y. A Bayesian Approach for Identifying miRNA Targets by Combining Sequence Prediction and Expression Profiling. Proc Int Joint Conf Bioinforma Syst Biol Intell Comput. 2009 Jan 01; 2009:185-189. PMID: 21234333.
      View in: PubMed
    78. Kang T, Ye FC, Gao S, Wang LD. Angiogenesis, Kaposi's Sarcoma and Kaposi's Sarcoma-Associated Herpesvirus. Virol Sin. 2008 Dec 01; 23(6):449-458. PMID: 19890492.
      View in: PubMed
    79. Zhou F, Li Q, Gao S. A sequence-independent in vitro transposon-based strategy for efficient cloning of genomes of large DNA viruses as bacterial artificial chromosomes. Nucleic Acids Res. 2009 Jan; 37(1):e2. PMID: 18988631; PMCID: PMC2615602.
    80. Qian LW, Greene W, Ye F, Gao S. Kaposi's sarcoma-associated herpesvirus disrupts adherens junctions and increases endothelial permeability by inducing degradation of VE-cadherin. J Virol. 2008 Dec; 82(23):11902-12. PMID: 18815301; PMCID: PMC2583667.
    81. Li Q, Zhou F, Ye F, Gao S. Genetic disruption of KSHV major latent nuclear antigen LANA enhances viral lytic transcriptional program. Virology. 2008 Sep 30; 379(2):234-44. PMID: 18684478; PMCID: PMC2626151.
    82. Liu H, Yue D, Zhang L, Bai Z, Lei X, Gao S, Huang Y. A MACHINE LEARNING APPROACH FOR miRNA TARGET PREDICTION. IEEE Int Workshop Genomic Signal Process Stat. 2008 Jun 08; 2008:1-3. PMID: 20514358.
      View in: PubMed
    83. Ye FC, Zhou FC, Xie JP, Kang T, Greene W, Kuhne K, Lei XF, Li QH, Gao S. Kaposi's sarcoma-associated herpesvirus latent gene vFLIP inhibits viral lytic replication through NF-kappaB-mediated suppression of the AP-1 pathway: a novel mechanism of virus control of latency. J Virol. 2008 May; 82(9):4235-49. PMID: 18305042; PMCID: PMC2293065.
    84. Meng J, Gao S, Huang Y. An Iterative Time Windowed Signature Algorithm for Time Dependent Transcription Module Discovery. IEEE Int Workshop Genomic Signal Process Stat. 2008; 2008:1-4. PMID: 21552463.
      View in: PubMed
    85. Xie J, Ajibade AO, Ye F, Kuhne K, Gao S. Reactivation of Kaposi's sarcoma-associated herpesvirus from latency requires MEK/ERK, JNK and p38 multiple mitogen-activated protein kinase pathways. Virology. 2008 Feb 05; 371(1):139-54. PMID: 17964626; PMCID: PMC2239004.
    86. Qian LW, Xie J, Ye F, Gao S. Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinases. J Virol. 2007 Jul; 81(13):7001-10. PMID: 17442715; PMCID: PMC1933284.
    87. Mutlu AD, Cavallin LE, Vincent L, Chiozzini C, Eroles P, Duran EM, Asgari Z, Hooper AT, La Perle KM, Hilsher C, Gao S, Dittmer DP, Rafii S, Mesri EA. In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma. Cancer Cell. 2007 Mar; 11(3):245-58. PMID: 17349582; PMCID: PMC2180156.
    88. Ye FC, Blackbourn DJ, Mengel M, Xie JP, Qian LW, Greene W, Yeh IT, Graham D, Gao S. Kaposi's sarcoma-associated herpesvirus promotes angiogenesis by inducing angiopoietin-2 expression via AP-1 and Ets1. J Virol. 2007 Apr; 81(8):3980-91. PMID: 17287278; PMCID: PMC1866109.
    89. Greene W, Kuhne K, Ye F, Chen J, Zhou F, Lei X, Gao S. Molecular biology of KSHV in relation to AIDS-associated oncogenesis. Cancer Treat Res. 2007; 133:69-127. PMID: 17672038; PMCID: PMC2798888.
    90. Nair P, Pan H, Stallings RL, Gao S. Recurrent genomic imbalances in primary effusion lymphomas. Cancer Genet Cytogenet. 2006 Dec; 171(2):119-21. PMID: 17116491; PMCID: PMC2799290.
    91. Majerciak V, Pripuzova N, McCoy JP, Gao S, Zheng ZM. Targeted disruption of Kaposi's sarcoma-associated herpesvirus ORF57 in the viral genome is detrimental for the expression of ORF59, K8alpha, and K8.1 and the production of infectious virus. J Virol. 2007 Feb; 81(3):1062-71. PMID: 17108026; PMCID: PMC1797518.
    92. Zhu FX, Li X, Zhou F, Gao S, Yuan Y. Functional characterization of Kaposi's sarcoma-associated herpesvirus ORF45 by bacterial artificial chromosome-based mutagenesis. J Virol. 2006 Dec; 80(24):12187-96. PMID: 17035322; PMCID: PMC1676278.
    93. Pan H, Xie J, Ye F, Gao S. Modulation of Kaposi's sarcoma-associated herpesvirus infection and replication by MEK/ERK, JNK, and p38 multiple mitogen-activated protein kinase pathways during primary infection. J Virol. 2006 Jun; 80(11):5371-82. PMID: 16699017; PMCID: PMC1472170.
    94. Xie J, Pan H, Yoo S, Gao S. Kaposi's sarcoma-associated herpesvirus induction of AP-1 and interleukin 6 during primary infection mediated by multiple mitogen-activated protein kinase pathways. J Virol. 2005 Dec; 79(24):15027-37. PMID: 16306573; PMCID: PMC1316010.
    95. Yoo SM, Zhou FC, Ye FC, Pan HY, Gao S. Early and sustained expression of latent and host modulating genes in coordinated transcriptional program of KSHV productive primary infection of human primary endothelial cells. Virology. 2005 Dec 05; 343(1):47-64. PMID: 16154170; PMCID: PMC2814456.
    96. Krishnan HH, Sharma-Walia N, Zeng L, Gao S, Chandran B. Envelope glycoprotein gB of Kaposi's sarcoma-associated herpesvirus is essential for egress from infected cells. J Virol. 2005 Sep; 79(17):10952-67. PMID: 16103147; PMCID: PMC1193577.
    97. Si MW, Jagirdar J, Zhang YJ, Gao S, Yeh IT. Detection of KSHV in transbronchial biopsies in patients with Kaposi sarcoma. Appl Immunohistochem Mol Morphol. 2005 Mar; 13(1):61-5. PMID: 15722795.
      View in: PubMed
    98. Deng JH, Zhang YJ, Wang XP, Gao S. Lytic replication-defective Kaposi's sarcoma-associated herpesvirus: potential role in infection and malignant transformation. J Virol. 2004 Oct; 78(20):11108-20. PMID: 15452231; PMCID: PMC521843.
    99. Ye FC, Zhou FC, Yoo SM, Xie JP, Browning PJ, Gao S. Disruption of Kaposi's sarcoma-associated herpesvirus latent nuclear antigen leads to abortive episome persistence. J Virol. 2004 Oct; 78(20):11121-9. PMID: 15452232; PMCID: PMC521844.
    100. Pan H, Zhou F, Gao S. Kaposi's sarcoma-associated herpesvirus induction of chromosome instability in primary human endothelial cells. Cancer Res. 2004 Jun 15; 64(12):4064-8. PMID: 15205312.
      View in: PubMed
    101. Luna RE, Zhou F, Baghian A, Chouljenko V, Forghani B, Gao S, Kousoulas KG. Kaposi's sarcoma-associated herpesvirus glycoprotein K8.1 is dispensable for virus entry. J Virol. 2004 Jun; 78(12):6389-98. PMID: 15163732; PMCID: PMC416545.
    102. Baillargeon J, Pollock BH, Leach CT, Gao S. The association of neoplasms and HIV infection in the correctional setting. Int J STD AIDS. 2004 May; 15(5):348-51. PMID: 15117507; PMCID: PMC2811392.
    103. Gao S, Deng JH, Zhou FC. Productive lytic replication of a recombinant Kaposi's sarcoma-associated herpesvirus in efficient primary infection of primary human endothelial cells. J Virol. 2003 Sep; 77(18):9738-49. PMID: 12941882; PMCID: PMC224610.
    104. Pan HY, Zhang YJ, Wang XP, Deng JH, Zhou FC, Gao S. Identification of a novel cellular transcriptional repressor interacting with the latent nuclear antigen of Kaposi's sarcoma-associated herpesvirus. J Virol. 2003 Sep; 77(18):9758-68. PMID: 12941884; PMCID: PMC224565.
    105. Wang XP, Gao S. Auto-activation of the transforming viral interferon regulatory factor encoded by Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8). J Gen Virol. 2003 Feb; 84(Pt 2):329-36. PMID: 12560564.
      View in: PubMed
    106. Baillargeon J, Leach CT, Deng JH, Gao S, Jenson HB. High prevalence of human herpesvirus 8 (HHV-8) infection in south Texas children. J Med Virol. 2002 Aug; 67(4):542-8. PMID: 12116002.
      View in: PubMed
    107. Jenson HB, Ench Y, Zhang Y, Gao S, Arrand JR, Mackett M. Characterization of an Epstein-Barr virus-related gammaherpesvirus from common marmoset (Callithrix jacchus). J Gen Virol. 2002 Jul; 83(Pt 7):1621-33. PMID: 12075080.
      View in: PubMed
    108. Zhou FC, Zhang YJ, Deng JH, Wang XP, Pan HY, Hettler E, Gao S. Efficient infection by a recombinant Kaposi's sarcoma-associated herpesvirus cloned in a bacterial artificial chromosome: application for genetic analysis. J Virol. 2002 Jun; 76(12):6185-96. PMID: 12021352; PMCID: PMC136188.
    109. Wang XP, Zhang YJ, Deng JH, Pan HY, Zhou FC, Gao S. Transcriptional regulation of Kaposi's sarcoma-associated herpesvirus-encoded oncogene viral interferon regulatory factor by a novel transcriptional silencer, Tis. J Biol Chem. 2002 Apr 05; 277(14):12023-31. PMID: 11821384.
      View in: PubMed
    Shou-Jiang's Networks
    Derived automatically from this person's publications.
    People in Profiles who have published with this person.
    Related Authors
    People who share related concepts with this person.