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Shao-Yao Ying, PhD

TitleProfessor of Cell & Neurobiology
InstitutionUniversity of Southern California
DepartmentIntegrative Anatomical Sciences
AddressBMT 303 1333 San Pablo Street
Health Sciences Campus
Los Angeles CA 90089
Phone+1 323 442 1859
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    Collapse Biography 
    Collapse Education and Training
    University of Wisconsin, Madison, WI, Madison, WisconsinPh.D.12/1969Ndocrinology/Reproductive Physiology

    Collapse Research 
    Collapse Research Activities and Funding
    Novel Molecular Profiling of Prostate Cancer Signatures
    NIH/NCI R01CA085722Jan 18, 2002 - Dec 31, 2007
    Role: Principal Investigator
    ACTIVIN-A AS A GROWTH FACTOR IN PROSTATE CANCER
    NIH/NIDDK R01DK047609Sep 30, 1993 - Aug 31, 1998
    Role: Principal Investigator
    FOLLISTATIN--NOVEL PROTEIN INHIBITS FSH RELEASE
    NIH/NICHD R01HD026635Apr 1, 1989 - Mar 31, 1993
    Role: Principal Investigator
    ACTIVIN, A MOLECULE WITH ACTIVITIES OPPOSITE TO INHIBIN
    NIH/NICHD R01HD022867Mar 1, 1988 - Feb 29, 1992
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lin SL, Ying S. Gene Silencing In Vitro and In Vivo Using Intronic MicroRNAs. Methods Mol Biol. 2018; 1733:107-126. PMID: 29435927.
      View in: PubMed
    2. Lin SL, Chang SE, Ying S. Transgene-Like Animal Models Using Intronic MicroRNAs. Methods Mol Biol. 2018; 1733:239-254. PMID: 29435938.
      View in: PubMed
    3. Lin SL, Ying S. Mechanism and Method for Generating Tumor-Free iPS Cells Using Intronic MicroRNA miR-302 Induction. Methods Mol Biol. 2018; 1733:265-282. PMID: 29435940.
      View in: PubMed
    4. Ying S, Fang W, Lin SL. The miR-302-Mediated Induction of Pluripotent Stem Cells (iPSC): Multiple Synergistic Reprogramming Mechanisms. Methods Mol Biol. 2018; 1733:283-304. PMID: 29435941.
      View in: PubMed
    5. Lin SL, Chang DC, Ying S. Isolation and Identification of Gene-Specific MicroRNAs. Methods Mol Biol. 2018; 1733:173-180. PMID: 29435932.
      View in: PubMed
    6. Ying S, Chang DC, Lin SL. The MicroRNA. Methods Mol Biol. 2018; 1733:1-25. PMID: 29435919.
      View in: PubMed
    7. Chang-Lin S, Hung A, Chang DC, Lin YW, Ying S, Lin SL. Novel glycylated sugar alcohols protect ESC-specific microRNAs from degradation in iPS cells. Nucleic Acids Res. 2016 06 02; 44(10):4894-906. PMID: 27001514; PMCID: PMC4889939.
    8. Deng JH, Deng P, Lin SL, Ying S. Gene silencing in vitro and in vivo using intronic microRNAs. Methods Mol Biol. 2015; 1218:321-40. PMID: 25319661.
      View in: PubMed
    9. Lin SL, Chang SJ, Ying S. Transgene-like animal models using intronic microRNAs. Methods Mol Biol. 2013; 936:279-94. PMID: 23007516.
      View in: PubMed
    10. Lin SL, Ying S. Mechanism and method for generating tumor-free iPS cells using intronic microRNA miR-302 induction. Methods Mol Biol. 2013; 936:295-312. PMID: 23007517.
      View in: PubMed
    11. Ying S, Chang DC, Lin SL. The MicroRNA. Methods Mol Biol. 2013; 936:1-19. PMID: 23007495.
      View in: PubMed
    12. Lin SL, Ying S. Gene silencing in vitro and in vivo using intronic microRNAs. Methods Mol Biol. 2013; 936:209-29. PMID: 23007511.
      View in: PubMed
    13. Lin SL, Chang DC, Ying S. Isolation and identification of gene-specific microRNAs. Methods Mol Biol. 2013; 936:271-8. PMID: 23007515.
      View in: PubMed
    14. Deng JH, Deng Q, Kuo CH, Delaney SW, Ying S. MiRNA targets of prostate cancer. Methods Mol Biol. 2013; 936:357-69. PMID: 23007521.
      View in: PubMed
    15. Kuo CH, Goldberg MD, Lin SL, Ying S, Zhong JF. Identify intronic microRNA with bioinformatics. Methods Mol Biol. 2013; 936:77-82. PMID: 23007500.
      View in: PubMed
    16. Kuo CH, Deng JH, Deng Q, Ying S. A novel role of miR-302/367 in reprogramming. Biochem Biophys Res Commun. 2012 Jan 06; 417(1):11-6. PMID: 22138244.
      View in: PubMed
    17. Lin SL, Chang DC, Ying S, Leu D, Wu DT. MicroRNA miR-302 inhibits the tumorigenecity of human pluripotent stem cells by coordinate suppression of the CDK2 and CDK4/6 cell cycle pathways. Cancer Res. 2010 Nov 15; 70(22):9473-82. PMID: 21062975.
      View in: PubMed
    18. Lin SL, Chang DC, Lin CH, Ying S, Leu D, Wu DT. Regulation of somatic cell reprogramming through inducible mir-302 expression. Nucleic Acids Res. 2011 Feb; 39(3):1054-65. PMID: 20870751; PMCID: PMC3035461.
    19. Ying S, Chang CP, Lin SL. Intron-mediated RNA interference, intronic microRNAs, and applications. Methods Mol Biol. 2010; 629:205-37. PMID: 20387152.
      View in: PubMed
    20. Ying S, Lin SL. Intron-mediated RNA interference and microRNA biogenesis. Methods Mol Biol. 2009; 487:387-413. PMID: 19301658.
      View in: PubMed
    21. Lin SL, Chang DC, Chang-Lin S, Lin CH, Wu DT, Chen DT, Ying S. Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state. RNA. 2008 Oct; 14(10):2115-24. PMID: 18755840; PMCID: PMC2553732.
    22. Lin SL, Chiang A, Chang D, Ying S. Loss of mir-146a function in hormone-refractory prostate cancer. RNA. 2008 Mar; 14(3):417-24. PMID: 18174313; PMCID: PMC2248249.
    23. Lin SL, Chang D, Chiang A, Ying S. Androgen receptor regulates CD168 expression and signaling in prostate cancer. Carcinogenesis. 2008 Feb; 29(2):282-90. PMID: 18174258.
      View in: PubMed
    24. Lin SL, Kim H, Ying S. Intron-mediated RNA interference and microRNA (miRNA). Front Biosci. 2008 Jan 01; 13:2216-30. PMID: 17981704.
      View in: PubMed
    25. Ying S, Chang DC, Lin SL. The microRNA (miRNA): overview of the RNA genes that modulate gene function. Mol Biotechnol. 2008 Mar; 38(3):257-68. PMID: 17999201.
      View in: PubMed
    26. Lin SL, Chang D, Ying S. Hyaluronan stimulates transformation of androgen-independent prostate cancer. Carcinogenesis. 2007 Feb; 28(2):310-20. PMID: 16864594.
      View in: PubMed
    27. Chen YG, Wang Q, Lin SL, Chang CD, Chuang J, Chung J, Ying S. Activin signaling and its role in regulation of cell proliferation, apoptosis, and carcinogenesis. Exp Biol Med (Maywood). 2006 May; 231(5):534-44. PMID: 16636301.
      View in: PubMed
    28. Lin SL, Chang SJ, Ying S. Transgene-like animal models using intronic microRNAs. Methods Mol Biol. 2006; 342:321-34. PMID: 16957386.
      View in: PubMed
    29. Lin SL, Ying S. Gene silencing in vitro and in vivo using intronic microRNAs. Methods Mol Biol. 2006; 342:295-312. PMID: 16957384.
      View in: PubMed
    30. Ying S, Chang DC, Miller JD, Lin SL. MicroRNA protocols. Perspectives. Methods Mol Biol. 2006; 342:351-8. PMID: 16957388.
      View in: PubMed
    31. Lin SL, Miller JD, Ying S. Intronic microRNA (miRNA). J Biomed Biotechnol. 2006; 2006(4):26818. PMID: 17057362; PMCID: PMC1559912.
    32. Lin SL, Chang DC, Ying S. Isolation and identification of gene-specific microRNAs. Methods Mol Biol. 2006; 342:313-20. PMID: 16957385.
      View in: PubMed
    33. Ying S, Chang DC, Miller JD, Lin SL. The microRNA: overview of the RNA gene that modulates gene functions. Methods Mol Biol. 2006; 342:1-18. PMID: 16957363.
      View in: PubMed
    34. Lin SL, Chang SJ, Ying S. Transcriptional control of Shh/Ptc1 signaling in embryonic development. Gene. 2006 Feb 15; 367:56-65. PMID: 16330160.
      View in: PubMed
    35. Ying S, Lin SL. Current perspectives in intronic micro RNAs (miRNAs). J Biomed Sci. 2006 Jan; 13(1):5-15. PMID: 16228283.
      View in: PubMed
    36. Ying S, Lin SL. MicroRNA: fine-tunes the function of genes in zebrafish. Biochem Biophys Res Commun. 2005 Sep 16; 335(1):1-4. PMID: 16018965.
      View in: PubMed
    37. Lin SL, Chang D, Ying S. Asymmetry of intronic pre-miRNA structures in functional RISC assembly. Gene. 2005 Aug 15; 356:32-8. PMID: 16005165; PMCID: PMC1788082.
    38. Ying S, Lin SL. Intronic microRNAs. Biochem Biophys Res Commun. 2005 Jan 21; 326(3):515-20. PMID: 15596130.
      View in: PubMed
    39. Ying S, Lin SL. Intron-derived microRNAs--fine tuning of gene functions. Gene. 2004 Nov 10; 342(1):25-8. PMID: 15527961.
      View in: PubMed
    40. Ying S. Complementary DNA libraries: an overview. Mol Biotechnol. 2004 Jul; 27(3):245-52. PMID: 15247497.
      View in: PubMed
    41. Ying S, Lin SL. Gene expression in precursor cells of prostate cancer associated with activin by combination of subtractive hybridization and microarray technologies. Biochem Biophys Res Commun. 2004 Jan 02; 313(1):104-9. PMID: 14672704.
      View in: PubMed
    42. Lin SL, Ying S. Combinational therapy for potential HIV-1 eradication and vaccination. Int J Oncol. 2004 Jan; 24(1):81-8. PMID: 14654944.
      View in: PubMed
    43. Lin SL, Chang D, Wu DY, Ying S. A novel RNA splicing-mediated gene silencing mechanism potential for genome evolution. Biochem Biophys Res Commun. 2003 Oct 24; 310(3):754-60. PMID: 14550267.
      View in: PubMed
    44. Huang JM, Lin TY, Chang D, Lin SL, Ying S. Truncated Bcl-2, a potential pre-metastatic marker in prostate cancer. Biochem Biophys Res Commun. 2003 Jul 11; 306(4):912-7. PMID: 12821128.
      View in: PubMed
    45. Lin SL, Ying S. mRNA/cDNA library construction using RNA-polymerase cycling reaction. Methods Mol Biol. 2003; 221:129-43. PMID: 12703739.
      View in: PubMed
    46. Ying S. Complementary DNA libraries: an overview. Methods Mol Biol. 2003; 221:1-12. PMID: 12703728.
      View in: PubMed
    47. Ying S, Lin SL. Subtractive cloning of differential genes using RNA-PCR. Methods Mol Biol. 2003; 221:253-9. PMID: 12703749.
      View in: PubMed
    48. Lin TY, Ying S. Subtractive hybridization for the identification of differentially expressed genes using uracil-dNA glycosylase and mung-bean nuclease. Methods Mol Biol. 2003; 221:239-51. PMID: 12703748.
      View in: PubMed
    49. Lin TY, Ying S. Assessment of the quality of mRNA libraries by agarose gel electrophoresis. Methods Mol Biol. 2003; 221:155-9. PMID: 12703741.
      View in: PubMed
    50. Ying S. Future perspectives. Methods Mol Biol. 2003; 221:311-29. PMID: 12703754.
      View in: PubMed
    51. Chen YG, Lui HM, Lin SL, Lee JM, Ying S. Regulation of cell proliferation, apoptosis, and carcinogenesis by activin. Exp Biol Med (Maywood). 2002 Feb; 227(2):75-87. PMID: 11815670.
      View in: PubMed
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