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Serghei Mangul

Title(s)Assistant Professor
Phone+1 323 442 0043
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bhat SP, Gangalum RK, Kim D, Mangul S, Kashyap RK, Zhou X, Elashoff D. Transcriptional profiling of single fiber cells in a transgenic paradigm of an inherited childhood cataract reveals absence of molecular heterogeneity. J Biol Chem. 2019 Sep 13; 294(37):13530-13544. PMID: 31243103.
      View in: PubMed
    2. Mangul S, Mosqueiro T, Abdill RJ, Duong D, Mitchell K, Sarwal V, Hill B, Brito J, Littman RJ, Statz B, Lam AK, Dayama G, Grieneisen L, Martin LS, Flint J, Eskin E, Blekhman R. Challenges and recommendations to improve the installability and archival stability of omics computational tools. PLoS Biol. 2019 Jun; 17(6):e3000333. PMID: 31220077.
      View in: PubMed
    3. LaPierre N, Mangul S, Alser M, Mandric I, Wu NC, Koslicki D, Eskin E. MiCoP: microbial community profiling method for detecting viral and fungal organisms in metagenomic samples. BMC Genomics. 2019 Jun 06; 20(Suppl 5):423. PMID: 31167634.
      View in: PubMed
    4. Mangul S, Martin LS, Hill BL, Lam AK, Distler MG, Zelikovsky A, Eskin E, Flint J. Systematic benchmarking of omics computational tools. Nat Commun. 2019 03 27; 10(1):1393. PMID: 30918265.
      View in: PubMed
    5. Mangul S, Martin LS, Langmead B, Sanchez-Galan JE, Toma I, Hormozdiari F, Pevzner P, Eskin E. How bioinformatics and open data can boost basic science in countries and universities with limited resources. Nat Biotechnol. 2019 03; 37(3):324-326. PMID: 30833765.
      View in: PubMed
    6. Mangul S, Martin LS, Eskin E, Blekhman R. Improving the usability and archival stability of bioinformatics software. Genome Biol. 2019 02 27; 20(1):47. PMID: 30813962.
      View in: PubMed
    7. Gangalum RK, Kim D, Kashyap RK, Mangul S, Zhou X, Elashoff D, Bhat SP. Spatial Analysis of Single Fiber Cells of the Developing Ocular Lens Reveals Regulated Heterogeneity of Gene Expression. iScience. 2018 Dec 21; 10:66-79. PMID: 30508719.
      View in: PubMed
    8. Chiang CWK, Mangul S, Robles C, Sankararaman S. A Comprehensive Map of Genetic Variation in the World's Largest Ethnic Group-Han Chinese. Mol Biol Evol. 2018 11 01; 35(11):2736-2750. PMID: 30169787.
      View in: PubMed
    9. Olde Loohuis LM, Mangul S, Ori APS, Jospin G, Koslicki D, Yang HT, Wu T, Boks MP, Lomen-Hoerth C, Wiedau-Pazos M, Cantor RM, de Vos WM, Kahn RS, Eskin E, Ophoff RA. Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia. Transl Psychiatry. 2018 05 10; 8(1):96. PMID: 29743478.
      View in: PubMed
    10. Mangul S, Martin LS, Eskin E. Involving undergraduates in genomics research to narrow the education-research gap. Nat Biotechnol. 2018 04 05; 36(4):369-371. PMID: 29621227.
      View in: PubMed
    11. Mangul S, Yang HT, Strauli N, Gruhl F, Porath HT, Hsieh K, Chen L, Daley T, Christenson S, Wesolowska-Andersen A, Spreafico R, Rios C, Eng C, Smith AD, Hernandez RD, Ophoff RA, Santana JR, Levanon EY, Woodruff PG, Burchard E, Seibold MA, Shifman S, Eskin E, Zaitlen N. ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues. Genome Biol. 2018 02 15; 19(1):36. PMID: 29548336.
      View in: PubMed
    12. Mangul S, Martin LS, Hoffmann A, Pellegrini M, Eskin E. Addressing the Digital Divide in Contemporary Biology: Lessons from Teaching UNIX. Trends Biotechnol. 2017 10; 35(10):901-903. PMID: 28720283.
      View in: PubMed
    13. Mangul S, Yang TH, Hormozdiari F, Dainis AM, Tseng E, Ashley EA, Zelikovsky A, Eskin E. HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads. IEEE Trans Nanobioscience. 2017 03; 16(2):108-115. PMID: 28328508.
      View in: PubMed
    14. Artyomenko A, Wu NC, Mangul S, Eskin E, Sun R, Zelikovsky A. Long Single-Molecule Reads Can Resolve the Complexity of the Influenza Virus Composed of Rare, Closely Related Mutant Variants. J Comput Biol. 2017 Jun; 24(6):558-570. PMID: 27901586.
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    15. Kang EY, Martin LJ, Mangul S, Isvilanonda W, Zou J, Ben-David E, Han B, Lusis AJ, Shifman S, Eskin E. Discovering Single Nucleotide Polymorphisms Regulating Human Gene Expression Using Allele Specific Expression from RNA-seq Data. Genetics. 2016 11; 204(3):1057-1064. PMID: 27765809.
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    16. Schokrpur S, Hu J, Moughon DL, Liu P, Lin LC, Hermann K, Mangul S, Guan W, Pellegrini M, Xu H, Wu L. CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma. Sci Rep. 2016 06 30; 6:29032. PMID: 27358011.
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    17. Mangul S, Caciula A, Al Seesi S, Brinza D, M?ndoiu I, Zelikovsky A. Transcriptome assembly and quantification from Ion Torrent RNA-Seq data. BMC Genomics. 2014; 15 Suppl 5:S7. PMID: 25082147.
      View in: PubMed
    18. Mangul S, Wu NC, Mancuso N, Zelikovsky A, Sun R, Eskin E. Accurate viral population assembly from ultra-deep sequencing data. Bioinformatics. 2014 Jun 15; 30(12):i329-37. PMID: 24932001.
      View in: PubMed
    19. Astrovskaya I, Tork B, Mangul S, Westbrooks K, Mandoiu I, Balfe P, Zelikovsky A. Inferring viral quasispecies spectra from 454 pyrosequencing reads. BMC Bioinformatics. 2011; 12 Suppl 6:S1. PMID: 21989211.
      View in: PubMed
    20. Nicolae M, Mangul S, Mandoiu II, Zelikovsky A. Estimation of alternative splicing isoform frequencies from RNA-Seq data. Algorithms Mol Biol. 2011 Apr 19; 6(1):9. PMID: 21504602.
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    21. Mangul S, Caciula A, Glebova O, Mandoiu I, Zelikovsky A. Improved transcriptome quantification and reconstruction from RNA-Seq reads using partial annotations. In Silico Biol. 2011-2012; 11(5-6):251-61. PMID: 23202426.
      View in: PubMed