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Rose K Lai, MD

Title(s)Clinical Associate Professor of Neurology (Part-Time)
AddressNTT 3407
Health Sciences Campus
Los Angeles CA 90089-9173
Phone+1 323 865 0341
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    Collapse Biography 
    Collapse Education and Training
    U of Western Ontario, London ON CanadaMD07/1996Medicine
    Columbia University, New York2000Neurology
    Memorial Sloan Kettering Cancer Center, New York2002Neuro-oncology
    McMaster University, Hamilton ON CanadaMS2005Epidemiology

    Collapse Research 
    Collapse Research Activities and Funding
    Functional Characterization of Glioma GWAS Variants
    NIH R01CA207972Aug 23, 2016 - Jul 31, 2020
    Role: Principal Investigator
    A pilot study of statin therapy and risk of malignant glioma
    NIH K07CA127468Sep 1, 2009 - Dec 31, 2011
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Phase I trial of intranasal NEO100, highly purified perillyl alcohol, in adult patients with recurrent glioblastoma. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab005. PMID: 33604574.
      View in: PubMed   Mentions:
    2. A functional variant on 20q13.33 related to glioma risk alters enhancer activity and modulates expression of multiple genes. Hum Mutat. 2020 Nov 10. PMID: 33169458.
      View in: PubMed   Mentions:    Fields:    
    3. Lack of association between modifiable exposures and glioma risk: a Mendelian randomization analysis. Neuro Oncol. 2020 02 20; 22(2):207-215. Saunders CN, Cornish AJ, Kinnersley B, Law PJ, Claus EB, Il'yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Houlston RS. PMID: 31665421.
      View in: PubMed   Mentions:    Fields:    
    4. Publisher Correction: Mendelian randomisation study of the relationship between vitamin D and risk of glioma. Sci Rep. 2019 May 23; 9(1):7924. Takahashi H, Cornish AJ, Sud A, Law PJ, Kinnersley B, Ostrom QT, Labreche K, Eckel-Passow JE, Armstrong GN, Claus EB, Il'yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Schoemaker MJ, Simon M, Hoffmann P, Nöthen MM, Jöckel KH, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Turnbull C, Houlston RS. PMID: 31118477.
      View in: PubMed   Mentions:    Fields:    
    5. Glioma risk associated with extent of estimated European genetic ancestry in African Americans and Hispanics. Int J Cancer. 2020 02 01; 146(3):739-748. Ostrom QT, Egan KM, Nabors LB, Gerke T, Thompson RC, Olson JJ, LaRocca R, Chowdhary S, Eckel-Passow JE, Armstrong G, Wiencke JK, Bernstein JL, Claus EB, Il'yasova D, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Houlston RS, Jenkins RB, Wrensch MR, Melin B, Amos CI, Huse JT, Barnholtz-Sloan JS, Bondy ML. PMID: 30963577.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Transcriptome-Wide Association Study Identifies New Candidate Susceptibility Genes for Glioma. Cancer Res. 2019 04 15; 79(8):2065-2071. Atkins I, Kinnersley B, Ostrom QT, Labreche K, Il'yasova D, Armstrong GN, Eckel-Passow JE, Schoemaker MJ, Nöthen MM, Barnholtz-Sloan JS, Swerdlow AJ, Simon M, Rajaraman P, Chanock SJ, Shildkraut J, Bernstein JL, Hoffmann P, Jöckel KH, Lai RK, Claus EB, Olson SH, Johansen C, Wrensch MR, Melin B, Jenkins RB, Sanson M, Bondy ML, Houlston RS. PMID: 30709929.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. Sex-specific gene and pathway modeling of inherited glioma risk. Neuro Oncol. 2019 01 01; 21(1):71-82. Ostrom QT, Coleman W, Huang W, Rubin JB, Lathia JD, Berens ME, Speyer G, Liao P, Wrensch MR, Eckel-Passow JE, Armstrong G, Rice T, Wiencke JK, McCoy LS, Hansen HM, Amos CI, Bernstein JL, Claus EB, Houlston RS, Il'yasova D, Jenkins RB, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Andersson U, Rajaraman P, Chanock SJ, Linet MS, Wang Z, Yeager M, Melin B, Bondy ML, Barnholtz-Sloan JS. PMID: 30124908.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    8. Aspirin, NSAIDs, and Glioma Risk: Original Data from the Glioma International Case-Control Study and a Meta-analysis. Cancer Epidemiol Biomarkers Prev. 2019 03; 28(3):555-562. Amirian ES, Ostrom QT, Armstrong GN, Lai RK, Gu X, Jacobs DI, Jalali A, Claus EB, Barnholtz-Sloan JS, Il'yasova D, Schildkraut JM, Ali-Osman F, Sadetzki S, Jenkins RB, Lachance DH, Olson SH, Bernstein JL, Merrell RT, Wrensch MR, Johansen C, Houlston RS, Scheurer ME, Shete S, Amos CI, Melin B, Bondy ML. PMID: 30482874.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    9. Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age. Int J Cancer. 2018 11 15; 143(10):2359-2366. Ostrom QT, Kinnersley B, Armstrong G, Rice T, Chen Y, Wiencke JK, McCoy LS, Hansen HM, Amos CI, Bernstein JL, Claus EB, Eckel-Passow JE, Il'yasova D, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Rubin JB, Andersson U, Rajaraman P, Chanock SJ, Linet MS, Wang Z, Yeager M, Houlston RS, Jenkins RB, Wrensch MR, Melin B, Bondy ML, Barnholtz-Sloan JS. PMID: 30152087.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. Sci Rep. 2018 05 09; 8(1):7352. Ostrom QT, Kinnersley B, Wrensch MR, Eckel-Passow JE, Armstrong G, Rice T, Chen Y, Wiencke JK, McCoy LS, Hansen HM, Amos CI, Bernstein JL, Claus EB, Il'yasova D, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Rubin JB, Lathia JD, Berens ME, Andersson U, Rajaraman P, Chanock SJ, Linet MS, Wang Z, Yeager M, Houlston RS, Jenkins RB, Melin B, Bondy ML, Barnholtz-Sloan JS. PMID: 29743610.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    11. Impact of atopy on risk of glioma: a Mendelian randomisation study. BMC Med. 2018 03 15; 16(1):42. Disney-Hogg L, Cornish AJ, Sud A, Law PJ, Kinnersley B, Jacobs DI, Ostrom QT, Labreche K, Eckel-Passow JE, Armstrong GN, Claus EB, Il'yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Schoemaker MJ, Simon M, Hoffmann P, Nöthen MM, Jöckel KH, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Houlston RS. PMID: 29540232.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    12. Influence of obesity-related risk factors in the aetiology of glioma. Br J Cancer. 2018 04; 118(7):1020-1027. Disney-Hogg L, Sud A, Law PJ, Cornish AJ, Kinnersley B, Ostrom QT, Labreche K, Eckel-Passow JE, Armstrong GN, Claus EB, Il'yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Swerdlow AJ, Simon M, Hoffmann P, Nöthen MM, Jöckel KH, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Houlston RS. PMID: 29531326.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    13. Mendelian randomisation study of the relationship between vitamin D and risk of glioma. Sci Rep. 2018 02 05; 8(1):2339. Takahashi H, Cornish AJ, Sud A, Law PJ, Kinnersley B, Ostrom QT, Labreche K, Eckel-Passow JE, Armstrong GN, Claus EB, Il'yasova D, Schildkraut J, Barnholtz-Sloan JS, Olson SH, Bernstein JL, Lai RK, Schoemaker MJ, Simon M, Hoffmann P, Nöthen MM, Jöckel KH, Chanock S, Rajaraman P, Johansen C, Jenkins RB, Melin BS, Wrensch MR, Sanson M, Bondy ML, Turnbull C, Houlston RS. PMID: 29402980.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    14. Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. Nat Genet. 2017 May; 49(5):789-794. PMID: 28346443.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    15. History of chickenpox in glioma risk: a report from the glioma international case-control study (GICC). Cancer Med. 2016 06; 5(6):1352-8. PMID: 26972449.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    16. Approaching a Scientific Consensus on the Association between Allergies and Glioma Risk: A Report from the Glioma International Case-Control Study. Cancer Epidemiol Biomarkers Prev. 2016 Feb; 25(2):282-90. PMID: 26908595.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    17. Targeted sequencing in chromosome 17q linkage region identifies familial glioma candidates in the Gliogene Consortium. Sci Rep. 2015 Feb 05; 5:8278. PMID: 25652157.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    18. A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study. Neuro Oncol. 2015 Jun; 17(6):854-61. PMID: 25586468.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansCTClinical Trials
    19. Germline mutations in shelterin complex genes are associated with familial glioma. J Natl Cancer Inst. 2015 Jan; 107(1):384. PMID: 25482530.
      View in: PubMed   Mentions: 74     Fields:    Translation:Humans
    20. Germline rearrangements in families with strong family history of glioma and malignant melanoma, colon, and breast cancer. Neuro Oncol. 2014 Oct; 16(10):1333-40. PMID: 24723567.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    21. Genome-wide methylation analyses in glioblastoma multiforme. PLoS One. 2014; 9(2):e89376. PMID: 24586730.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    22. Rituximab, methotrexate, procarbazine, and vincristine followed by consolidation reduced-dose whole-brain radiotherapy and cytarabine in newly diagnosed primary CNS lymphoma: final results and long-term outcome. J Clin Oncol. 2013 Nov 01; 31(31):3971-9. PMID: 24101038.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCTClinical Trials
    23. Description of selected characteristics of familial glioma patients - results from the Gliogene Consortium. Eur J Cancer. 2013 Apr; 49(6):1335-45. PMID: 23290425.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    24. A variable age of onset segregation model for linkage analysis, with correction for ascertainment, applied to glioma. Cancer Epidemiol Biomarkers Prev. 2012 Dec; 21(12):2242-51. PMID: 22962404.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    25. Insight in glioma susceptibility through an analysis of 6p22.3, 12p13.33-12.1, 17q22-23.2 and 18q23 SNP genotypes in familial and non-familial glioma. Hum Genet. 2012 Sep; 131(9):1507-17. PMID: 22688887.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    26. HMG CoA reductase inhibitors, NSAIDs and risk of glioma. Int J Cancer. 2012 Sep 15; 131(6):E1031-7. PMID: 22419506.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    27. Regression of recurrent malignant gliomas with convection-enhanced delivery of topotecan. Neurosurgery. 2011 Dec; 69(6):1272-9; discussion 1279-80. Bruce JN, Fine RL, Canoll P, Yun J, Kennedy BC, Rosenfeld SS, Sands SA, Surapaneni K, Lai R, Yanes CL, Bagiella E, DeLaPaz RL. PMID: 21562434.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    28. Genome-wide high-density SNP linkage search for glioma susceptibility loci: results from the Gliogene Consortium. Cancer Res. 2011 Dec 15; 71(24):7568-75. PMID: 22037877.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    29. Survey of familial glioma and role of germline p16INK4A/p14ARF and p53 mutation. Fam Cancer. 2010 Sep; 9(3):413-21. Robertson LB, Armstrong GN, Olver BD, Lloyd AL, Shete S, Lau C, Claus EB, Barnholtz-Sloan J, Lai R, Il'yasova D, Schildkraut J, Bernstein JL, Olson SH, Jenkins RB, Yang P, Rynearson AL, Rynerason AL, Wrensch M, McCoy L, Wienkce JK, McCarthy B, Davis F, Vick NA, Johansen C, Bødtcher H, Sadetzki S, Bruchim RB, Yechezkel GH, Andersson U, Melin BS, Bondy ML, Houlston RS. PMID: 20455025.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    30. The timing of cranial radiation in elderly patients with newly diagnosed glioblastoma multiforme. Neuro Oncol. 2010 Feb; 12(2):190-8. Lai R, Hershman DL, Doan T, Neugut AI. PMID: 20150386.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    31. Combined immunochemotherapy with reduced whole-brain radiotherapy for newly diagnosed primary CNS lymphoma. J Clin Oncol. 2007 Oct 20; 25(30):4730-5. PMID: 17947720.
      View in: PubMed   Mentions:
    32. GLIOGENE an International Consortium to Understand Familial Glioma. Cancer Epidemiol Biomarkers Prev. 2007 Sep; 16(9):1730-4. Malmer B, Adatto P, Armstrong G, Barnholtz-Sloan J, Bernstein JL, Claus E, Davis F, Houlston R, Il'yasova D, Jenkins R, Johansen C, Lai R, Lau C, McCarthy B, Nielsen H, Olson SH, Sadetzki S, Shete S, Wiklund F, Wrensch M, Yang P, Bondy M. PMID: 17855690.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    33. Treatment-induced leukoencephalopathy in primary CNS lymphoma: a clinical and autopsy study. Neurology. 2004 Feb 10; 62(3):451-6. Lai R, Abrey LE, Rosenblum MK, DeAngelis LM. PMID: 14872029.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansPHPublic Health
    34. Primary CNS lymphoma: a whole-brain disease? Neurology. 2002 Nov 26; 59(10):1557-62. Lai R, Rosenblum MK, DeAngelis LM. PMID: 12451197.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
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