Nyam-Osor Chimge, PhD

TitleAssistant Professor of Research Medicine
InstitutionUniversity of Southern California
AddressHMR 911A
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 442 3914
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Amzaleg Y, Ji J, Kittivanichkul D, E Törnqvist A, Windahl S, Sabag E, Khalid AB, Sternberg H, West M, Katzenellenbogen JA, Krum SA, Chimge N, Schones DE, Gabet Y, Ohlsson C, Frenkel B. Estrogens and selective estrogen receptor modulators differentially antagonize Runx2 in ST2 mesenchymal progenitor cells. J Steroid Biochem Mol Biol. 2018 May 08. PMID: 29751107.
      View in: PubMed
    2. Zhou B, Flodby P, Luo J, Castillo DR, Liu Y, Yu FX, McConnell A, Varghese B, Li G, Chimge N, Sunohara M, Koss MN, Elatre W, Conti P, Liebler JM, Yang C, Marconett CN, Laird-Offringa IA, Minoo P, Guan K, Stripp BR, Crandall ED, Borok Z. Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis. J Clin Invest. 2018 Mar 01; 128(3):970-984. PMID: 29400695.
      View in: PubMed
    3. Chimge N, Ahmed-Alnassar S, Frenkel B. Relationship between RUNX1 and AXIN1 in ER-negative versus ER-positive Breast Cancer. Cell Cycle. 2017 Feb 16; 16(4):312-318. PMID: 28055379.
      View in: PubMed
    4. Yang Y, He S, Wang Q, Li F, Kwak MJ, Chen S, O'Connell D, Zhang T, Pirooz SD, Jeon Y, Chimge N, Frenkel B, Choi Y, Aldrovandi GM, Oh BH, Yuan Z, Liang C. Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase. Mol Cell. 2016 05 19; 62(4):507-19. PMID: 27203177; PMCID: PMC4875571 [Available on 05/19/17].
    5. Morimoto E, Li M, Khalid AB, Krum SA, Chimge N, Frenkel B. Glucocorticoids Hijack Runx2 to Stimulate Wif1 for Suppression of Osteoblast Growth and Differentiation. J Cell Physiol. 2017 Jan; 232(1):145-53. PMID: 27061521.
      View in: PubMed
    6. Chimge N, Little GH, Baniwal SK, Adisetiyo H, Xie Y, Zhang T, O'Laughlin A, Liu ZY, Ulrich P, Martin A, Mhawech-Fauceglia P, Ellis MJ, Tripathy D, Groshen S, Liang C, Li Z, Schones DE, Frenkel B. RUNX1 prevents oestrogen-mediated AXIN1 suppression and ß-catenin activation in ER-positive breast cancer. Nat Commun. 2016 Feb 26; 7:10751. PMID: 26916619; PMCID: PMC4773428.
    7. Martin A, Xiong J, Koromila T, Ji JS, Chang S, Song YS, Miller JL, Han CY, Kostenuik P, Krum SA, Chimge N, Gabet Y, Frenkel B. Estrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association. Bone. 2015 Jun; 75:96-104. PMID: 25701138; PMCID: PMC4387095.
    8. Little GH, Baniwal SK, Adisetiyo H, Groshen S, Chimge N, Kim SY, Khalid O, Hawes D, Jones JO, Pinski J, Schones DE, Frenkel B. Differential effects of RUNX2 on the androgen receptor in prostate cancer: synergistic stimulation of a gene set exemplified by SNAI2 and subsequent invasiveness. Cancer Res. 2014 May 15; 74(10):2857-68. PMID: 24648349; PMCID: PMC4051204.
    9. Baniwal SK, Chimge N, Jordan VC, Tripathy D, Frenkel B. Prolactin-induced protein (PIP) regulates proliferation of luminal A type breast cancer cells in an estrogen-independent manner. PLoS One. 2014; 8(6):e62361. PMID: 23755096; PMCID: PMC3670933.
    10. Chimge N, Frenkel B. The RUNX family in breast cancer: relationships with estrogen signaling. Oncogene. 2013 Apr 25; 32(17):2121-30. PMID: 23045283.
      View in: PubMed
    11. Baniwal SK, Little GH, Chimge N, Frenkel B. Runx2 controls a feed-forward loop between androgen and prolactin-induced protein (PIP) in stimulating T47D cell proliferation. J Cell Physiol. 2012 May; 227(5):2276-82. PMID: 21809344; PMCID: PMC3376385.
    12. Chimge N, Makeyev AV, Waigel SJ, Enkhmandakh B, Bayarsaihan D. PI3K/Akt-dependent functions of TFII-I transcription factors in mouse embryonic stem cells. J Cell Biochem. 2012 Apr; 113(4):1122-31. PMID: 22274952.
      View in: PubMed
    13. Chimge N, Baniwal SK, Little GH, Chen YB, Kahn M, Tripathy D, Borok Z, Frenkel B. Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2. Breast Cancer Res. 2011; 13(6):R127. PMID: 22151997; PMCID: PMC3326569.
    14. Chimge N, Baniwal SK, Luo J, Coetzee S, Khalid O, Berman BP, Tripathy D, Ellis MJ, Frenkel B. Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness. Clin Cancer Res. 2012 Feb 01; 18(3):901-11. PMID: 22147940; PMCID: PMC3277803.
    15. Pramanik S, Cui X, Wang HY, Chimge N, Hu G, Shen L, Gao R, Li H. Segmental duplication as one of the driving forces underlying the diversity of the human immunoglobulin heavy chain variable gene region. BMC Genomics. 2011 Jan 27; 12:78. PMID: 21272357; PMCID: PMC3042411.
    16. Chimge N, Bayarsaihan D. Generation of neural crest progenitors from human embryonic stem cells. J Exp Zool B Mol Dev Evol. 2010 Mar 15; 314(2):95-103. PMID: 19780036.
      View in: PubMed
    17. Enkhmandakh B, Makeyev AV, Erdenechimeg L, Ruddle FH, Chimge N, Tussie-Luna MI, Roy AL, Bayarsaihan D. Essential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic development. Proc Natl Acad Sci U S A. 2009 Jan 06; 106(1):181-6. PMID: 19109438; PMCID: PMC2629217.
    18. Chimge N, Makeyev AV, Ruddle FH, Bayarsaihan D. Identification of the TFII-I family target genes in the vertebrate genome. Proc Natl Acad Sci U S A. 2008 Jul 01; 105(26):9006-10. PMID: 18579769; PMCID: PMC2449355.
    19. Hirayasu K, Ohashi J, Tanaka H, Kashiwase K, Ogawa A, Takanashi M, Satake M, Jia GJ, Chimge N, Sideltseva EW, Tokunaga K, Yabe T. Evidence for natural selection on leukocyte immunoglobulin-like receptors for HLA class I in Northeast Asians. Am J Hum Genet. 2008 May; 82(5):1075-83. PMID: 18439545; PMCID: PMC2427302.
    20. Chimge N, Mungunsukh O, Ruddle F, Bayarsaihan D. Gene expression analysis of TFII-I modulated genes in mouse embryonic fibroblasts. J Exp Zool B Mol Dev Evol. 2007 May 15; 308(3):225-35. PMID: 17094079.
      View in: PubMed
    21. Chimge N, Mungunsukh O, Ruddle F, Bayarsaihan D. Expression profiling of BEN regulated genes in mouse embryonic fibroblasts. J Exp Zool B Mol Dev Evol. 2007 May 15; 308(3):209-24. PMID: 17041962.
      View in: PubMed
    22. Chimge N, Ruddle F, Bayarsaihan D. Laser-assisted microdissection (LAM) in developmental biology. J Exp Zool B Mol Dev Evol. 2007 Mar 15; 308(2):113-8. PMID: 17016827.
      View in: PubMed
    23. Greenawalt DM, Cui X, Wu Y, Lin Y, Wang HY, Luo M, Tereshchenko IV, Hu G, Li JY, Chu Y, Azaro MA, Decoste CJ, Chimge N, Gao R, Shen L, Shih WJ, Lange K, Li H. Strong correlation between meiotic crossovers and haplotype structure in a 2.5-Mb region on the long arm of chromosome 21. Genome Res. 2006 Feb; 16(2):208-14. PMID: 16385099; PMCID: PMC1361716.
    24. Li H, Cui X, Pramanik S, Chimge N. Genetic diversity of the human immunoglobulin heavy chain VH region. Immunol Rev. 2002 Dec; 190:53-68. PMID: 12493006.
      View in: PubMed
    25. Chimge N, Batsuuri J. Interethnic genetic differentiation: HLA class I antigens in the population of Mongolia. Am J Hum Biol. 1999 Sep; 11(5):603-618. PMID: 11533979.
      View in: PubMed