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Nikolaos Skandalis, PhD

Title(s)Associate Professor of Research Medicine
Address2020 Zonal Avenue
Off Campus
Los Angeles CA 90033
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    Collapse Biography 
    Collapse Education and Training
    Imperial College, London, EnglandPhD & Diploma of Imperial College (DIC)2005Biology
    Imperial College at Wye, Ashford, EnglandMSc1998Biological Crop Protection
    Aristotle University of Thessaloniki, Thessaloniki, GreeceBSc-MSc1996Plant Science
    Collapse Awards and Honors
    Institute of Molecular Biology and Biotechnology2001  - 2005Fellowship for post-graduate studies
    Novartis Pharmaceuticals UK Ltd1998Novartis award for best MSc thesis project
    Greek Fellowship Foundtain (IKY)1997  - 2001Fellowship for Post-graduate studies

    Collapse Overview 
    Collapse Overview
    Plants are colonized by commensal, symbiotic, plant-associated and pathogenic bacteria. Several prokaryotic species antagonize for this niche by using antibiotics and enhancing their competence. Moreover, they have evolved to interact with the plant host. Dr. Skandalis's main research interest is the control of plant pathogenic bacteria with the lowest environmental impact. He translates basic research of the triple interaction among plants, bacterial pathogens and bacterial biological control agents (BCA) to outcomes that would support disease management strategies under field conditions. His recruitment at the USC Keck School of Medicine provides a unique opportunity to combine his specialties in plant-microbe interactions with substantial knowledge of established USC faculty in antibiotic resistance, to study the effect of modern agriculture to transmission of antibiotic resistance in the food chain. He is also involved in multidisciplinary projects that led to the development of environmental friendly plant protection products that have either a direct effect against pathogenic bacteria (silver or copper nanoparticles, natural extracts, dual function fertilizers) or elicit plant defenses (organic pesticides, bacterial elicitors).

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Effect of Silver Nanoparticles Size, Produced Using Plant Extract from Arbutus unedo, on Their Antibacterial Efficacy. Nanomaterials (Basel). 2017 Jul 10; 7(7). Skandalis N, Dimopoulou A, Georgopoulou A, Gallios N, Papadopoulos D, Tsipas D, Theologidis I, Michailidis N, Chatzinikolaidou M. PMID: 28698511.
      View in: PubMed   Mentions:
    2. Effect of pyraclostrobin application on viral and bacterial diseases of tomato. Plant Disease. 2017; 7(100):1321-1330. Skandalis N., Dimopoulou A., Beri D., Tzima A., Malandraki I., Theologidis I., Bitivanos S., Varveri C., Klitsinaris T., Vassilakos N.
    3. Plant Pathology. 2016; 884. Katis N., Velisariou D., Goumas D., Karaoglanidis G., Lagopodi A., Maliogka V., Panopoulos N.J., Sinapidou E., Skandalis N., Hatziloukas E.
    4. Bacteria Murmur: Application of an Acoustic Biosensor for Plant Pathogen Detection. PLoS One. 2015; 10(7):e0132773. Papadakis G, Skandalis N, Dimopoulou A, Glynos P, Gizeli E. PMID: 26177507.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. Targeting injectisomes of virulence: Benefits of thirty years of research on bacterial secretion systems, to crop protection. Hellenic Plant Protection Journal. 2012; (5):31-47. Skandalis N., Sarris P.F., Panopoulos N.J.
    6. Phytobacterial Type VI Secretion System - Gene Distribution, Phylogeny, Structure and Biological Functions. Plant Pathology. 2011. Sarris P.F., Trantas E.A., Skandalis N., Tampakaki A.P., Kapanidou M., Kokkinidis M., Panopoulos N.J.
    7. In silico analysis reveals multiple putative type VI secretion systems and effector proteins in Pseudomonas syringae pathovars. Mol Plant Pathol. 2010 Nov; 11(6):795-804. Sarris PF, Skandalis N, Kokkinidis M, Panopoulos NJ. PMID: 21091602.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    8. Playing the HRP: Evolution of Our Understanding of HRP genes. Ann Rev Phytopathology. 2010; (48):347-370. Tampakaki N., Skandalis N., Sarris P.F., Charova S., Gazi T., Kokkinidis M., Panopoulos N.J.
    9. Engineered polyamine catabolism preinduces tolerance of tobacco to bacteria and oomycetes. Plant Physiol. 2009 Apr; 149(4):1970-81. Moschou PN, Sarris PF, Skandalis N, Andriopoulou AH, Paschalidis KA, Panopoulos NJ, Roubelakis-Angelakis KA. PMID: 19218362.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    10. Molecular polymorphism between populations of Pseudoperonospora cubensis from Greece and the Czech Republic and their phytopathological and phylogenetic implications. . Plant Pathology. 2009; (58):933-943. Sarris P., Abdelhalim M., Kitner M., Skandalis N., Panopoulos N.J, Doulis A., Lebeda A.
    11. Evolution of the Oomycete Chitin Synthase genes. Phytopathol. Mediterr. 2009; (48):334. Skandalis N., Spanou Z., Badreddine I., Dumas B., Bottin A.
    12. Cell wall chitosaccharides are essential components and exposed patterns of the phytopathogenic oomycete Aphanomyces euteiches. Eukaryot Cell. 2008 Nov; 7(11):1980-93. Badreddine I, Lafitte C, Heux L, Skandalis N, Spanou Z, Martinez Y, Esquerré-Tugayé MT, Bulone V, Dumas B, Bottin A. PMID: 18806214.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    13. Bacterial Species isolated from untreated olive mill wastewaters reduce its toxic load and produce high added value antioxidants. FEBS J. 2008; (275):363-364. Skandalis N., Spanou Z., Mavrakis T., Saloustrou K., Xenos C., Theophilou S., Piceno Y., Kouvarakis A., Andersen G., Stefanou E., Panopoulos N.J.
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