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Mikko Tuomas Huuskonen

Title(s)Postdoctoral Scholar - Research Associate
AddressZNI 301, 1501 San Pablo Street
Health Sciences Campus
Los Angeles CA 90033
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. On the intersection between systemic infection, brain vascular dysfunction and dementia. Brain. 2021 May 11. Huuskonen MT, Kisler K, Sagare AP, Zlokovic BV. PMID: 33974045.
      View in: PubMed   Mentions:    Fields:    
    2. Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A. J Exp Med. 2021 Apr 05; 218(4). Nikolakopoulou AM, Wang Y, Ma Q, Sagare AP, Montagne A, Huuskonen MT, Rege SV, Kisler K, Dai Z, Körbelin J, Herz J, Zhao Z, Zlokovic BV. PMID: 33533918.
      View in: PubMed   Mentions:    Fields:    
    3. An arylthiazyne derivative is a potent inhibitor of lipid peroxidation and ferroptosis providing neuroprotection in vitro and in vivo. Sci Rep. 2021 Feb 10; 11(1):3518. Keuters MH, Keksa-Goldsteine V, Dhungana H, Huuskonen MT, Pomeshchik Y, Savchenko E, Korhonen PK, Singh Y, Wojciechowski S, Lehtonen Š, Kanninen KM, Malm T, Sirviö J, Muona A, Koistinaho M, Goldsteins G, Koistinaho J. PMID: 33568697.
      View in: PubMed   Mentions:    Fields:    
    4. A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease. Transl Stroke Res. 2021 Feb; 12(1):15-30. Stringer MS, Lee H, Huuskonen MT, MacIntosh BJ, Brown R, Montagne A, Atwi S, Ramirez J, Jansen MA, Marshall I, Black SE, Zlokovic BV, Benveniste H, Wardlaw JM. PMID: 32936435.
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    5. Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation. J Neuroinflammation. 2020 Jun 19; 17(1):194. Kolosowska N, Gotkiewicz M, Dhungana H, Giudice L, Giugno R, Box D, Huuskonen MT, Korhonen P, Scoyni F, Kanninen KM, Ylä-Herttuala S, Turunen TA, Turunen MP, Koistinaho J, Malm T. PMID: 32560730.
      View in: PubMed   Mentions: 1     Fields:    
    6. Building vascular roadmaps: A novel toolset for visualizing and annotating whole mouse brain vasculature. Lab Anim (NY). 2020 06; 49(6):175-176. Kisler K, Huuskonen MT, Zlokovic BV. PMID: 32424313.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    7. Proteomic and functional analyses in disease models reveal CLN5 protein involvement in mitochondrial dysfunction. Cell Death Discov. 2020; 6:18. Doccini S, Morani F, Nesti C, Pezzini F, Calza G, Soliymani R, Signore G, Rocchiccioli S, Kanninen KM, Huuskonen MT, Baumann MH, Simonati A, Lalowski MM, Santorelli FM. PMID: 32257390.
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    8. Undetectable gadolinium brain retention in individuals with an age-dependent blood-brain barrier breakdown in the hippocampus and mild cognitive impairment. Alzheimers Dement. 2019 12; 15(12):1568-1575. Montagne A, Huuskonen MT, Rajagopal G, Sweeney MD, Nation DA, Sepehrband F, D'Orazio LM, Harrington MG, Chui HC, Law M, Toga AW, Zlokovic BV. PMID: 31862169.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Loss of Cln5 leads to altered Gad1 expression and deficits in interneuron development in mice. Hum Mol Genet. 2019 10 01; 28(19):3309-3322. Singh Y, Leinonen H, Fazaludeen F, Jaronen M, Guest D, Buckley N, Byts N, Oksa P, Jalkanen K, Iqbal I, Huuskonen M, Savchenko E, Keksa-Goldsteine V, Chew S, Myllyharju J, Tanila H, Ooi L, Koistinaho J, Kanninen KM, Malm T. PMID: 31294445.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    10. Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss. Nat Neurosci. 2019 07; 22(7):1089-1098. Nikolakopoulou AM, Montagne A, Kisler K, Dai Z, Wang Y, Huuskonen MT, Sagare AP, Lazic D, Sweeney MD, Kong P, Wang M, Owens NC, Lawson EJ, Xie X, Zhao Z, Zlokovic BV. PMID: 31235908.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    11. PPARß/d-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1?E9 astrocytes. Glia. 2019 01; 67(1):146-159. Konttinen H, Gureviciene I, Oksanen M, Grubman A, Loppi S, Huuskonen MT, Korhonen P, Lampinen R, Keuters M, Belaya I, Tanila H, Kanninen KM, Goldsteins G, Landreth G, Koistinaho J, Malm T. PMID: 30453390.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    12. CuII(atsm) Attenuates Neuroinflammation. Front Neurosci. 2018; 12:668. Choo XY, Liddell JR, Huuskonen MT, Grubman A, Moujalled D, Roberts J, Kysenius K, Patten L, Quek H, Oikari LE, Duncan C, James SA, McInnes LE, Hayne DJ, Donnelly PS, Pollari E, Vähätalo S, Lejavová K, Kettunen MI, Malm T, Koistinaho J, White AR, Kanninen KM. PMID: 30319344.
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    13. HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage. Brain Behav Immun. 2018 10; 73:670-681. Loppi S, Kolosowska N, Kärkkäinen O, Korhonen P, Huuskonen M, Grubman A, Dhungana H, Wojciechowski S, Pomeshchik Y, Giordano M, Kagechika H, White A, Auriola S, Koistinaho J, Landreth G, Hanhineva K, Kanninen K, Malm T. PMID: 30063972.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    14. Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation. J Neuroinflammation. 2017 Dec 04; 14(1):237. Dhungana H, Huuskonen MT, Jaronen M, Lemarchant S, Ali H, Keksa-Goldsteine V, Goldsteins G, Kanninen KM, Koistinaho J, Malm T. PMID: 29202856.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    15. DHCR24 exerts neuroprotection upon inflammation-induced neuronal death. J Neuroinflammation. 2017 Nov 07; 14(1):215. Martiskainen H, Paldanius KMA, Natunen T, Takalo M, Marttinen M, Leskelä S, Huber N, Mäkinen P, Bertling E, Dhungana H, Huuskonen M, Honkakoski P, Hotulainen P, Rilla K, Koistinaho J, Soininen H, Malm T, Haapasalo A, Hiltunen M. PMID: 29115990.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    16. The Copper bis(thiosemicarbazone) Complex CuII(atsm) Is Protective Against Cerebral Ischemia Through Modulation of the Inflammatory Milieu. Neurotherapeutics. 2017 04; 14(2):519-532. Huuskonen MT, Tuo QZ, Loppi S, Dhungana H, Korhonen P, McInnes LE, Donnelly PS, Grubman A, Wojciechowski S, Lejavova K, Pomeshchik Y, Periviita L, Kosonen L, Giordano M, Walker FR, Liu R, Bush AI, Koistinaho J, Malm T, White AR, Lei P, Kanninen KM. PMID: 28050710.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    17. Lack of collagen XV is protective after ischemic stroke in mice. Cell Death Dis. 2017 01 12; 8(1):e2541. Dhungana H, Huuskonen MT, Pihlajaniemi T, Heljasvaara R, Vivien D, Kanninen KM, Malm T, Koistinaho J, Lemarchant S. PMID: 28079884.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    18. Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy. Sci Rep. 2016 09 14; 6:33176. Huuskonen MT, Loppi S, Dhungana H, Keksa-Goldsteine V, Lemarchant S, Korhonen P, Wojciechowski S, Pollari E, Valonen P, Koponen J, Takashima A, Landreth G, Goldsteins G, Malm T, Koistinaho J, Kanninen KM. PMID: 27624652.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
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