Loading...
Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Michele T. Pato, MD

    TitleClinical Professor of Psychiatry & The Behavioral Sciences (Part Time)
    SchoolKeck School of Medicine of USC
    DepartmentPsychiatry and The Behavioral Sciences
    AddressCSC-2200 2250 Alcazar Street
    Health Sciences Campus
    Los Angeles California 90089-9074
    Phone+1 323 442 4000
    Emailmpato@usc.edu
    vCardDownload vCard

      Collapse Overview 
      Collapse Overview
      Michele Pato, MD is Professor and Associate Chair for Education, Della Martin Chair in Psychiatry and Associate Dean for Academic Scholarship at the Keck School of Medicine, Department of Psychiatry at the University of Southern California (USC). She is the Principal Investigator of the Genomic Psychiatry Cohort, developed clinical trials in pharmacologic and cognitive behavioral treatments of psychiatric illnesses, and teaches students and colleagues how to teach research and clinical skills. Dr. Pato is internationally known for her genetic research, OCD clinical research and teaching. She is the Co-Director of the OCD Treatment and Research Program at Keck School of Medicine, USC.


      Collapse ORNG Applications 
      Collapse In The News

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Huang AY, Yu D, Davis LK, Sul JH, Tsetsos F, Ramensky V, Zelaya I, Ramos EM, Osiecki L, Chen JA, McGrath LM, Illmann C, Sandor P, Barr CL, Grados M, Singer HS, Nöthen MM, Hebebrand J, King RA, Dion Y, Rouleau G, Budman CL, Depienne C, Worbe Y, Hartmann A, Müller-Vahl KR, Stuhrmann M, Aschauer H, Stamenkovic M, Schloegelhofer M, Konstantinidis A, Lyon GJ, McMahon WM, Barta C, Tarnok Z, Nagy P, Batterson JR, Rizzo R, Cath DC, Wolanczyk T, Berlin C, Malaty IA, Okun MS, Woods DW, Rees E, Pato CN, Pato M, Knowles JA, Posthuma D, Pauls DL, Cox NJ, Neale BM, Freimer NB, Paschou P, Mathews CA, Scharf JM, Coppola G. Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome. Neuron. 2017 Jun 21; 94(6):1101-1111.e7. PMID: 28641109.
        View in: PubMed
      2. Hartz SM, Horton AC, Oehlert M, Carey CE, Agrawal A, Bogdan R, Chen LS, Hancock DB, Johnson EO, Pato CN, Pato M, Rice JP, Bierut LJ. Association Between Substance Use Disorder and Polygenic Liability to Schizophrenia. Biol Psychiatry. 2017 Jun 06. PMID: 28739213.
        View in: PubMed
      3. Hartz SM, Horton AC, Hancock DB, Baker TB, Caporaso NE, Chen LS, Hokanson JE, Lutz SM, Marazita ML, McNeil DW, Pato CN, Pato M, Johnson EO, Bierut LJ. Genetic correlation between smoking behaviors and schizophrenia. Schizophr Res. 2017 Mar 08. PMID: 28285025.
        View in: PubMed
      4. Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A, Holmans PA, Pinto D, Gujral M, Brandler WM, Malhotra D, Wang Z, Fajarado KVF, Maile MS, Ripke S, Agartz I, Albus M, Alexander M, Amin F, Atkins J, Bacanu SA, Belliveau RA, Bergen SE, Bertalan M, Bevilacqua E, Bigdeli TB, Black DW, Bruggeman R, Buccola NG, Buckner RL, Bulik-Sullivan B, Byerley W, Cahn W, Cai G, Cairns MJ, Campion D, Cantor RM, Carr VJ, Carrera N, Catts SV, Chambert KD, Cheng W, Cloninger CR, Cohen D, Cormican P, Craddock N, Crespo-Facorro B, Crowley JJ, Curtis D, Davidson M, Davis KL, Degenhardt F, Del Favero J, DeLisi LE, Dikeos D, Dinan T, Djurovic S, Donohoe G, Drapeau E, Duan J, Dudbridge F, Eichhammer P, Eriksson J, Escott-Price V, Essioux L, Fanous AH, Farh KH, Farrell MS, Frank J, Franke L, Freedman R, Freimer NB, Friedman JI, Forstner AJ, Fromer M, Genovese G, Georgieva L, Gershon ES, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, Gratten J, de Haan L, Hamshere ML, Hansen M, Hansen T, Haroutunian V, Hartmann AM, Henskens FA, Herms S, Hirschhorn JN, Hoffmann P, Hofman A, Huang H, Ikeda M, Joa I, Kähler AK, Kahn RS, Kalaydjieva L, Karjalainen J, Kavanagh D, Keller MC, Kelly BJ, Kennedy JL, Kim Y, Knowles JA, Konte B, Laurent C, Lee P, Lee SH, Legge SE, Lerer B, Levy DL, Liang KY, Lieberman J, Lönnqvist J, Loughland CM, Magnusson PKE, Maher BS, Maier W, Mallet J, Mattheisen M, Mattingsdal M, McCarley RW, McDonald C, McIntosh AM, Meier S, Meijer CJ, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mokrab Y, Morris DW, Müller-Myhsok B, Murphy KC, Murray RM, Myin-Germeys I, Nenadic I, Nertney DA, Nestadt G, Nicodemus KK, Nisenbaum L, Nordin A, O'Callaghan E, O'Dushlaine C, Oh SY, Olincy A, Olsen L, O'Neill FA, Van Os J, Pantelis C, Papadimitriou GN, Parkhomenko E, Pato M, Paunio T, Perkins DO, Pers TH, Pietiläinen O, Pimm J, Pocklington AJ, Powell J, Price A, Pulver AE, Purcell SM, Quested D, Rasmussen HB, Reichenberg A, Reimers MA, Richards AL, Roffman JL, Roussos P, Ruderfer DM, Salomaa V, Sanders AR, Savitz A, Schall U, Schulze TG, Schwab SG, Scolnick EM, Scott RJ, Seidman LJ, Shi J, Silverman JM, Smoller JW, Söderman E, Spencer CCA, Stahl EA, Strengman E, Strohmaier J, Stroup TS, Suvisaari J, Svrakic DM, Szatkiewicz JP, Thirumalai S, Tooney PA, Veijola J, Visscher PM, Waddington J, Walsh D, Webb BT, Weiser M, Wildenauer DB, Williams NM, Williams S, Witt SH, Wolen AR, Wormley BK, Wray NR, Wu JQ, Zai CC, Adolfsson R, Andreassen OA, Blackwood DHR, Bramon E, Buxbaum JD, Cichon S, Collier DA, Corvin A, Daly MJ, Darvasi A, Domenici E, Esko T, Gejman PV, Gill M, Gurling H, Hultman CM, Iwata N, Jablensky AV, Jönsson EG, Kendler KS, Kirov G, Knight J, Levinson DF, Li QS, McCarroll SA, McQuillin A, Moran JL, Mowry BJ, Nöthen MM, Ophoff RA, Owen MJ, Palotie A, Pato CN, Petryshen TL, Posthuma D, Rietschel M, Riley BP, Rujescu D, Sklar P, St Clair D, Walters JTR, Werge T, Sullivan PF, O'Donovan MC, Scherer SW, Neale BM, Sebat J. Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nat Genet. 2017 Jan; 49(1):27-35. PMID: 27869829.
        View in: PubMed
      5. McCarthy S, Das S, Kretzschmar W, Delaneau O, Wood AR, Teumer A, Kang HM, Fuchsberger C, Danecek P, Sharp K, Luo Y, Sidore C, Kwong A, Timpson N, Koskinen S, Vrieze S, Scott LJ, Zhang H, Mahajan A, Veldink J, Peters U, Pato C, van Duijn CM, Gillies CE, Gandin I, Mezzavilla M, Gilly A, Cocca M, Traglia M, Angius A, Barrett JC, Boomsma D, Branham K, Breen G, Brummett CM, Busonero F, Campbell H, Chan A, Chen S, Chew E, Collins FS, Corbin LJ, Smith GD, Dedoussis G, Dorr M, Farmaki AE, Ferrucci L, Forer L, Fraser RM, Gabriel S, Levy S, Groop L, Harrison T, Hattersley A, Holmen OL, Hveem K, Kretzler M, Lee JC, McGue M, Meitinger T, Melzer D, Min JL, Mohlke KL, Vincent JB, Nauck M, Nickerson D, Palotie A, Pato M, Pirastu N, McInnis M, Richards JB, Sala C, Salomaa V, Schlessinger D, Schoenherr S, Slagboom PE, Small K, Spector T, Stambolian D, Tuke M, Tuomilehto J, Van den Berg LH, Van Rheenen W, Volker U, Wijmenga C, Toniolo D, Zeggini E, Gasparini P, Sampson MG, Wilson JF, Frayling T, de Bakker PI, Swertz MA, McCarroll S, Kooperberg C, Dekker A, Altshuler D, Willer C, Iacono W, Ripatti S, Soranzo N, Walter K, Swaroop A, Cucca F, Anderson CA, Myers RM, Boehnke M, McCarthy MI, Durbin R. A reference panel of 64,976 haplotypes for genotype imputation. Nat Genet. 2016 Oct; 48(10):1279-83. PMID: 27548312.
        View in: PubMed
      6. Besterman AD, Williams JK, Reus VI, Pato M, Voglmaier SM, Mathews CA. The Role of Regional Conferences in Research Resident Career Development: The California Psychiatry Research Resident Retreat. Acad Psychiatry. 2017 Apr; 41(2):272-277. PMID: 27178277.
        View in: PubMed
      7. Montano C, Taub MA, Jaffe A, Briem E, Feinberg JI, Trygvadottir R, Idrizi A, Runarsson A, Berndsen B, Gur RC, Moore TM, Perry RT, Fugman D, Sabunciyan S, Yolken RH, Hyde TM, Kleinman JE, Sobell JL, Pato CN, Pato M, Go RC, Nimgaonkar V, Weinberger DR, Braff D, Gur RE, Fallin MD, Feinberg AP. Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study. JAMA Psychiatry. 2016 May 01; 73(5):506-14. PMID: 27074206.
        View in: PubMed
      8. Guffanti G, Gaudi S, Klengel T, Fallon JH, Mangalam H, Madduri R, Rodriguez A, DeCrescenzo P, Glovienka E, Sobell J, Klengel C, Pato M, Ressler KJ, Pato C, Macciardi F. LINE1 insertions as a genomic risk factor for schizophrenia: Preliminary evidence from an affected family. Am J Med Genet B Neuropsychiatr Genet. 2016 Jun; 171(4):534-45. PMID: 26990047.
        View in: PubMed
      9. Thrall GC, Coverdale JH, Benjamin S, Wiggins A, Lane CJ, Pato M. A Randomized Controlled Trial of Team-Based Learning Versus Lectures with Break-Out Groups on Knowledge Retention. Acad Psychiatry. 2016 Oct; 40(5):755-60. PMID: 26883529.
        View in: PubMed
      10. Perlman G, Kotov R, Fu J, Bromet EJ, Fochtmann LJ, Medeiros H, Pato M, Pato CN. Symptoms of psychosis in schizophrenia, schizoaffective disorder, and bipolar disorder: A comparison of African Americans and Caucasians in the Genomic Psychiatry Cohort. Am J Med Genet B Neuropsychiatr Genet. 2016 Jun; 171(4):546-55. PMID: 26663585.
        View in: PubMed
      11. Bigdeli TB, Ripke S, Bacanu SA, Lee SH, Wray NR, Gejman PV, Rietschel M, Cichon S, St Clair D, Corvin A, Kirov G, McQuillin A, Gurling H, Rujescu D, Andreassen OA, Werge T, Blackwood DH, Pato CN, Pato M, Malhotra AK, O'Donovan MC, Kendler KS, Fanous AH. Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness. Am J Med Genet B Neuropsychiatr Genet. 2016 Mar; 171B(2):276-89. PMID: 26663532.
        View in: PubMed
      12. Estrada E, Hartz SM, Tran J, Hilty DM, Sklar P, Smoller JW, Pato M, Pato CN. Nicotine dependence and psychosis in Bipolar disorder and Schizoaffective disorder, Bipolar type. Am J Med Genet B Neuropsychiatr Genet. 2016 Jun; 171(4):521-4. PMID: 26467098; PMCID: PMC4950843.
      13. Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH, Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL. Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. Am J Hum Genet. 2015 Oct 01; 97(4):576-92. PMID: 26430803; PMCID: PMC4596916.
      14. Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, McGrath JJ, Mehta D, Stahl EA, Zhao Q, Kendler KS, Sullivan PF, Price AL, O'Donovan M, Okada Y, Mowry BJ, Raychaudhuri S, Wray NR, Byerley W, Cahn W, Cantor RM, Cichon S, Cormican P, Curtis D, Djurovic S, Escott-Price V, Gejman PV, Georgieva L, Giegling I, Hansen TF, Ingason A, Kim Y, Konte B, Lee PH, McIntosh A, McQuillin A, Morris DW, Nöthen MM, O'Dushlaine C, Olincy A, Olsen L, Pato CN, Pato M, Pickard BS, Posthuma D, Rasmussen HB, Rietschel M, Rujescu D, Schulze TG, Silverman JM, Thirumalai S, Werge T, Agartz I, Amin F, Azevedo MH, Bass N, Black DW, Blackwood DH, Bruggeman R, Buccola NG, Choudhury K, Cloninger RC, Corvin A, Craddock N, Daly MJ, Datta S, Donohoe GJ, Duan J, Dudbridge F, Fanous A, Freedman R, Freimer NB, Friedl M, Gill M, Gurling H, De Haan L, Hamshere ML, Hartmann AM, Holmans PA, Kahn RS, Keller MC, Kenny E, Kirov GK, Krabbendam L, Krasucki R, Lawrence J, Lencz T, Levinson DF, Lieberman JA, Lin DY, Linszen DH, Magnusson PK, Maier W, Malhotra AK, Mattheisen M, Mattingsdal M, McCarroll SA, Medeiros H, Melle I, Milanova V, Myin-Germeys I, Neale BM, Ophoff RA, Owen MJ, Pimm J, Purcell SM, Puri V, Quested DJ, Rossin L, Ruderfer D, Sanders AR, Shi J, Sklar P, St Clair D, Stroup TS, Van Os J, Visscher PM, Wiersma D, Zammit S, Bridges SL, Choi HK, Coenen MJ, de Vries N, Dieud P, Greenberg JD, Huizinga TW, Padyukov L, Siminovitch KA, Tak PP, Worthington J, De Jager PL, Denny JC, Gregersen PK, Klareskog L, Mariette X, Plenge RM, van Laar M, van Riel P. New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. Int J Epidemiol. 2015 Oct; 44(5):1706-21. PMID: 26286434; PMCID: PMC4881824 [Available on 10/01/16].
      15. Tang VK, Pato M, Sobell JL, Hammond TC, Valdez MM, Lane CJ, Pato CN. Substance use associated with short sleep duration in patients with schizophrenia or schizoaffective disorder. Am J Med Genet B Neuropsychiatr Genet. 2016 Jun; 171(4):525-33. PMID: 26345478.
        View in: PubMed
      16. Malaspina D, Walsh-Messinger J, Antonius D, Dracxler R, Rothman K, Puthota J, Gilman C, Feuerstein JL, Keefe D, Goetz D, Goetz RR, Buckley P, Lehrer DS, Pato M, Pato C. Parental age effects on odor sensitivity in healthy subjects and schizophrenia patients. Am J Med Genet B Neuropsychiatr Genet. 2016 Jun; 171(4):513-20. PMID: 26224136.
        View in: PubMed
      17. Lehrer DS, Pato M, Nahhas RW, Miller BR, Malaspina D, Buckley PF, Sobell JL, Walsh-Messinger J, Pato CN. Paternal age effect: Replication in schizophrenia with intriguing dissociation between bipolar with and without psychosis. Am J Med Genet B Neuropsychiatr Genet. 2016 06; 171(4):495-505. PMID: 26183902.
        View in: PubMed
      18. Usher CL, Handsaker RE, Esko T, Tuke MA, Weedon MN, Hastie AR, Cao H, Moon JE, Kashin S, Fuchsberger C, Metspalu A, Pato CN, Pato M, McCarthy MI, Boehnke M, Altshuler DM, Frayling TM, Hirschhorn JN, McCarroll SA. Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity. Nat Genet. 2015 Aug; 47(8):921-5. PMID: 26098870; PMCID: PMC4712930.
      19. Sassano-Higgins SA, Pato M. Pindolol augmentation of selective serotonin reuptake inhibitors and clomipramine for the treatment of obsessive-compulsive disorder: A meta-analysis. J Pharmacol Pharmacother. 2015 Jan-Mar; 6(1):36-8. PMID: 25709352; PMCID: PMC4319248.
      20. Gomes JB, Cordioli A, Van Noppen B, Pato M, Wolitzky-Taylor K, Gonçalves F, Heldt E. Family Accommodation Scale for Obsessive-Compulsive Disorder-Interviewer-Rated (FAS-IR), Brazilian Portuguese version: internal consistency, reliability, and exploratory factor analysis. Compr Psychiatry. 2015 Feb; 57:155-9. PMID: 25496698.
        View in: PubMed
      21. Duan J, Shi J, Fiorentino A, Leites C, Chen X, Moy W, Chen J, Alexandrov BS, Usheva A, He D, Freda J, O'Brien NL, McQuillin A, Sanders AR, Gershon ES, DeLisi LE, Bishop AR, Gurling HM, Pato M, Levinson DF, Kendler KS, Pato CN, Gejman PV. A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder. Am J Hum Genet. 2014 Dec 04; 95(6):744-53. PMID: 25434007; PMCID: PMC4259974.
      22. Yu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER, Derks EM, Evans P, Edlund CK, Crane J, Fagerness JA, Osiecki L, Gallagher P, Gerber G, Haddad S, Illmann C, McGrath LM, Mayerfeld C, Arepalli S, Barlassina C, Barr CL, Bellodi L, Benarroch F, Berrió GB, Bienvenu OJ, Black DW, Bloch MH, Brentani H, Bruun RD, Budman CL, Camarena B, Campbell DD, Cappi C, Silgado JC, Cavallini MC, Chavira DA, Chouinard S, Cook EH, Cookson MR, Coric V, Cullen B, Cusi D, Delorme R, Denys D, Dion Y, Eapen V, Egberts K, Falkai P, Fernandez T, Fournier E, Garrido H, Geller D, Gilbert DL, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Hardy J, Heiman GA, Hemmings SM, Herrera LD, Hezel DM, Hoekstra PJ, Jankovic J, Kennedy JL, King RA, Konkashbaev AI, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Lupoli S, Macciardi F, Maier W, Manunta P, Marconi M, McCracken JT, Mesa Restrepo SC, Moessner R, Moorjani P, Morgan J, Muller H, Murphy DL, Naarden AL, Nurmi E, Ochoa WC, Ophoff RA, Pakstis AJ, Pato M, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner T, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosário MC, Rosenberg D, Ruhrmann S, Sabatti C, Salvi E, Sampaio AS, Samuels J, Sandor P, Service SK, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Turiel M, Valencia Duarte AV, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Weale M, Weiss R, Wendland JR, Westenberg HG, Shugart YY, Hounie AG, Miguel EC, Nicolini H, Wagner M, Ruiz-Linares A, Cath DC, McMahon W, Posthuma D, Oostra BA, Nestadt G, Rouleau GA, Purcell S, Jenike MA, Heutink P, Hanna GL, Conti DV, Arnold PD, Freimer NB, Stewart SE, Knowles JA, Cox NJ, Pauls DL. Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. Am J Psychiatry. 2015 Jan; 172(1):82-93. PMID: 25158072; PMCID: PMC4282594.
      23. Arnedo J, Svrakic DM, Del Val C, Romero-Zaliz R, Hernández-Cuervo H, Fanous AH, Pato M, Pato CN, de Erausquin GA, Cloninger CR, Zwir I. Uncovering the hidden risk architecture of the schizophrenias: confirmation in three independent genome-wide association studies. Am J Psychiatry. 2015 Feb 01; 172(2):139-53. PMID: 25219520.
        View in: PubMed
      24. Hartz SM, Bierut LJ, Pato M. In reply. JAMA Psychiatry. 2014 Aug; 71(8):969. PMID: 25102905.
        View in: PubMed
      25. McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL, Bellodi L, Benarroch F, Bienvenu OJ, Black DW, Bloch MH, Bruun RD, Budman CL, Camarena B, Cath DC, Cavallini MC, Chouinard S, Coric V, Cullen B, Delorme R, Denys D, Derks EM, Dion Y, Rosário MC, Eapen V, Evans P, Falkai P, Fernandez TV, Garrido H, Geller D, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Heiman GA, Hemmings SM, Herrera LD, Hounie AG, Jankovic J, Kennedy JL, King RA, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Lochner C, Lowe TL, Lyon GJ, Macciardi F, Maier W, McCracken JT, McMahon W, Murphy DL, Naarden AL, Neale BM, Nurmi E, Pakstis AJ, Pato M, Pato CN, Piacentini J, Pittenger C, Pollak Y, Reus VI, Richter MA, Riddle M, Robertson MM, Rosenberg D, Rouleau GA, Ruhrmann S, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Tischfield JA, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Shugart YY, Miguel EC, Nicolini H, Oostra BA, Moessner R, Wagner M, Ruiz-Linares A, Heutink P, Nestadt G, Freimer N, Petryshen T, Posthuma D, Jenike MA, Cox NJ, Hanna GL, Brentani H, Scherer SW, Arnold PD, Stewart SE, Mathews CA, Knowles JA, Cook EH, Pauls DL, Wang K, Scharf JM. Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study. J Am Acad Child Adolesc Psychiatry. 2014 Aug; 53(8):910-9. PMID: 25062598; PMCID: PMC4218748.
      26. Gomes JB, Van Noppen B, Pato M, Braga DT, Meyer E, Bortoncello CF, Cordioli AV. Patient and family factors associated with family accommodation in obsessive-compulsive disorder. Psychiatry Clin Neurosci. 2014 Aug; 68(8):621-30. PMID: 24521250.
        View in: PubMed
      27. Hartz SM, Pato CN, Medeiros H, Cavazos-Rehg P, Sobell JL, Knowles JA, Bierut LJ, Pato M. Comorbidity of severe psychotic disorders with measures of substance use. JAMA Psychiatry. 2014 Mar; 71(3):248-54. PMID: 24382686; PMCID: PMC4060740.
      28. Pato M. What Do You Need to Know About Leadership? Acad Psychiatry. 2006 Jul; 30(4):281-2. PMID: 27518093.
        View in: PubMed
      29. Rees E, Walters JT, Chambert KD, O'Dushlaine C, Szatkiewicz J, Richards AL, Georgieva L, Mahoney-Davies G, Legge SE, Moran JL, Genovese G, Levinson D, Morris DW, Cormican P, Kendler KS, O'Neill FA, Riley B, Gill M, Corvin A, Sklar P, Hultman C, Pato C, Pato M, Sullivan PF, Gejman PV, McCarroll SA, O'Donovan MC, Owen MJ, Kirov G. CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1. Hum Mol Genet. 2014 Mar 15; 23(6):1669-76. PMID: 24163246; PMCID: PMC3929090.
      30. Davis LK, Yu D, Keenan CL, Gamazon ER, Konkashbaev AI, Derks EM, Neale BM, Yang J, Lee SH, Evans P, Barr CL, Bellodi L, Benarroch F, Berrio GB, Bienvenu OJ, Bloch MH, Blom RM, Bruun RD, Budman CL, Camarena B, Campbell D, Cappi C, Cardona Silgado JC, Cath DC, Cavallini MC, Chavira DA, Chouinard S, Conti DV, Cook EH, Coric V, Cullen BA, Deforce D, Delorme R, Dion Y, Edlund CK, Egberts K, Falkai P, Fernandez TV, Gallagher PJ, Garrido H, Geller D, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Haddad S, Heiman GA, Hemmings SM, Hounie AG, Illmann C, Jankovic J, Jenike MA, Kennedy JL, King RA, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Macciardi F, McCracken JT, McGrath LM, Mesa Restrepo SC, Moessner R, Morgan J, Muller H, Murphy DL, Naarden AL, Ochoa WC, Ophoff RA, Osiecki L, Pakstis AJ, Pato M, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner TJ, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosàrio MC, Rosenberg D, Rouleau GA, Ruhrmann S, Ruiz-Linares A, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Valencia Duarte AV, Vallada H, Van Nieuwerburgh F, Veenstra-Vanderweele J, Walitza S, Wang Y, Wendland JR, Westenberg HG, Shugart YY, Miguel EC, McMahon W, Wagner M, Nicolini H, Posthuma D, Hanna GL, Heutink P, Denys D, Arnold PD, Oostra BA, Nestadt G, Freimer NB, Pauls DL, Wray NR, Stewart SE, Mathews CA, Knowles JA, Cox NJ, Scharf JM. Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genet. 2013 Oct; 9(10):e1003864. PMID: 24204291; PMCID: PMC3812053.
      31. Bigdeli TB, Maher BS, Zhao Z, Sun J, Medeiros H, Akula N, McMahon FJ, Carvalho C, Ferreira SR, Azevedo MH, Knowles JA, Pato M, Pato CN, Fanous AH. Association study of 83 candidate genes for bipolar disorder in chromosome 6q selected using an evidence-based prioritization algorithm. Am J Med Genet B Neuropsychiatr Genet. 2013 Dec; 162B(8):898-906. PMID: 24123842.
        View in: PubMed
      32. Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, Andreassen OA, Anjorin A, Anney R, Anttila V, Arking DE, Asherson P, Azevedo MH, Backlund L, Badner JA, Bailey AJ, Banaschewski T, Barchas JD, Barnes MR, Barrett TB, Bass N, Battaglia A, Bauer M, Bayés M, Bellivier F, Bergen SE, Berrettini W, Betancur C, Bettecken T, Biederman J, Binder EB, Black DW, Blackwood DH, Bloss CS, Boehnke M, Boomsma DI, Breen G, Breuer R, Bruggeman R, Cormican P, Buccola NG, Buitelaar JK, Bunney WE, Buxbaum JD, Byerley WF, Byrne EM, Caesar S, Cahn W, Cantor RM, Casas M, Chakravarti A, Chambert K, Choudhury K, Cichon S, Cloninger CR, Collier DA, Cook EH, Coon H, Cormand B, Corvin A, Coryell WH, Craig DW, Craig IW, Crosbie J, Cuccaro ML, Curtis D, Czamara D, Datta S, Dawson G, Day R, De Geus EJ, Degenhardt F, Djurovic S, Donohoe GJ, Doyle AE, Duan J, Dudbridge F, Duketis E, Ebstein RP, Edenberg HJ, Elia J, Ennis S, Etain B, Fanous A, Farmer AE, Ferrier IN, Flickinger M, Fombonne E, Foroud T, Frank J, Franke B, Fraser C, Freedman R, Freimer NB, Freitag CM, Friedl M, Frisén L, Gallagher L, Gejman PV, Georgieva L, Gershon ES, Geschwind DH, Giegling I, Gill M, Gordon SD, Gordon-Smith K, Green EK, Greenwood TA, Grice DE, Gross M, Grozeva D, Guan W, Gurling H, De Haan L, Haines JL, Hakonarson H, Hallmayer J, Hamilton SP, Hamshere ML, Hansen TF, Hartmann AM, Hautzinger M, Heath AC, Henders AK, Herms S, Hickie IB, Hipolito M, Hoefels S, Holmans PA, Holsboer F, Hoogendijk WJ, Hottenga JJ, Hultman CM, Hus V, Ingason A, Ising M, Jamain S, Jones EG, Jones I, Jones L, Tzeng JY, Kähler AK, Kahn RS, Kandaswamy R, Keller MC, Kennedy JL, Kenny E, Kent L, Kim Y, Kirov GK, Klauck SM, Klei L, Knowles JA, Kohli MA, Koller DL, Konte B, Korszun A, Krabbendam L, Krasucki R, Kuntsi J, Kwan P, Landén M, Långström N, Lathrop M, Lawrence J, Lawson WB, Leboyer M, Ledbetter DH, Lee PH, Lencz T, Lesch KP, Levinson DF, Lewis CM, Li J, Lichtenstein P, Lieberman JA, Lin DY, Linszen DH, Liu C, Lohoff FW, Loo SK, Lord C, Lowe JK, Lucae S, MacIntyre DJ, Madden PA, Maestrini E, Magnusson PK, Mahon PB, Maier W, Malhotra AK, Mane SM, Martin CL, Martin NG, Mattheisen M, Matthews K, Mattingsdal M, McCarroll SA, McGhee KA, McGough JJ, McGrath PJ, McGuffin P, McInnis MG, McIntosh A, McKinney R, McLean AW, McMahon FJ, McMahon WM, McQuillin A, Medeiros H, Medland SE, Meier S, Melle I, Meng F, Meyer J, Middeldorp CM, Middleton L, Milanova V, Miranda A, Monaco AP, Montgomery GW, Moran JL, Moreno-De-Luca D, Morken G, Morris DW, Morrow EM, Moskvina V, Muglia P, Mühleisen TW, Muir WJ, Müller-Myhsok B, Murtha M, Myers RM, Myin-Germeys I, Neale MC, Nelson SF, Nievergelt CM, Nikolov I, Nimgaonkar V, Nolen WA, Nöthen MM, Nurnberger JI, Nwulia EA, Nyholt DR, O'Dushlaine C, Oades RD, Olincy A, Oliveira G, Olsen L, Ophoff RA, Osby U, Owen MJ, Palotie A, Parr JR, Paterson AD, Pato CN, Pato M, Penninx BW, Pergadia ML, Pericak-Vance MA, Pickard BS, Pimm J, Piven J, Posthuma D, Potash JB, Poustka F, Propping P, Puri V, Quested DJ, Quinn EM, Ramos-Quiroga JA, Rasmussen HB, Raychaudhuri S, Rehnström K, Reif A, Ribasés M, Rice JP, Rietschel M, Roeder K, Roeyers H, Rossin L, Rothenberger A, Rouleau G, Ruderfer D, Rujescu D, Sanders AR, Sanders SJ, Santangelo SL, Sergeant JA, Schachar R, Schalling M, Schatzberg AF, Scheftner WA, Schellenberg GD, Scherer SW, Schork NJ, Schulze TG, Schumacher J, Schwarz M, Scolnick E, Scott LJ, Shi J, Shilling PD, Shyn SI, Silverman JM, Slager SL, Smalley SL, Smit JH, Smith EN, Sonuga-Barke EJ, St Clair D, State M, Steffens M, Steinhausen HC, Strauss JS, Strohmaier J, Stroup TS, Sutcliffe JS, Szatmari P, Szelinger S, Thirumalai S, Thompson RC, Todorov AA, Tozzi F, Treutlein J, Uhr M, van den Oord EJ, Van Grootheest G, Van Os J, Vicente AM, Vieland VJ, Vincent JB, Visscher PM, Walsh CA, Wassink TH, Watson SJ, Weissman MM, Werge T, Wienker TF, Wijsman EM, Willemsen G, Williams N, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013 Sep; 45(9):984-94. PMID: 23933821; PMCID: PMC3800159.
      33. Pato M, Cobb RT, Lusskin SI, Schardt C. Journal club for faculty or residents: a model for lifelong learning and maintenance of certification. Int Rev Psychiatry. 2013 Jun; 25(3):276-83. PMID: 23859090.
        View in: PubMed
      34. Aberg KA, Liu Y, Bukszár J, McClay JL, Khachane AN, Andreassen OA, Blackwood D, Corvin A, Djurovic S, Gurling H, Ophoff R, Pato CN, Pato M, Riley B, Webb T, Kendler K, O'Donovan M, Craddock N, Kirov G, Owen M, Rujescu D, St Clair D, Werge T, Hultman CM, Delisi LE, Sullivan P, van den Oord EJ. A comprehensive family-based replication study of schizophrenia genes. JAMA Psychiatry. 2013 Jun; 70(6):573-81. PMID: 23894747.
        View in: PubMed
      35. Pato M, Sobell JL, Medeiros H, Abbott C, Sklar BM, Buckley PF, Bromet EJ, Escamilla MA, Fanous AH, Lehrer DS, Macciardi F, Malaspina D, McCarroll SA, Marder SR, Moran J, Morley CP, Nicolini H, Perkins DO, Purcell SM, Rapaport MH, Sklar P, Smoller JW, Knowles JA, Pato CN. The genomic psychiatry cohort: partners in discovery. Am J Med Genet B Neuropsychiatr Genet. 2013 Jun; 162B(4):306-12. PMID: 23650244; PMCID: PMC3729260.
      36. Zisook S, Boland R, Cowley D, Cyr RL, Pato M, Thrall G. Teaching scholarly activity in psychiatric training: years 6 and 7. Acad Psychiatry. 2013 Mar 01; 37(2):82-6. PMID: 23475234; PMCID: PMC3835692.
      37. Pato M, Cyr RL, Manley LN, Morley CP. What to learn and how to teach it: five years of pre-meetings for training directors in psychiatry. Acad Psychiatry. 2013 Mar 01; 37(2):76-81. PMID: 23475232; PMCID: PMC3820421.
      38. Zisook S, Anzia J, Atri A, Baroni A, Clayton P, Haller E, Lomax JW, Mann JJ, Oquendo MA, Pato M, Perez-Rodriguez MM, Prabhakar D, Sen S, Thrall G, Yaseen ZS. Teaching evidence-based approaches to suicide risk assessment and prevention that enhance psychiatric training. Compr Psychiatry. 2013 Apr; 54(3):201-8. PMID: 22995449; PMCID: PMC3529811.
      39. Pataki C, Pato M, Sugar J, Rizzo AS, Parsons TD, St George C, Kenny P. Virtual patients as novel teaching tools in psychiatry. Acad Psychiatry. 2012 Sep 01; 36(5):398-400. PMID: 22983473.
        View in: PubMed
      40. Bourgeois JA, Yager J, Chisolm MS, Zisook S, Riba M, Levy BR, Newmark T, Aggarwal NK, Caplan JP, Balon R, Munro S, Pato M. Why I like being an academic psychiatrist. Acad Psychiatry. 2012 Sep 01; 36(5):422-7. PMID: 22983479.
        View in: PubMed
      41. Fanous AH, Middleton FA, Gentile K, Amdur RL, Maher BS, Zhao Z, Sun J, Medeiros H, Carvalho C, Ferreira SR, Macedo A, Knowles JA, Azevedo MH, Pato M, Pato CN. Genetic overlap of schizophrenia and bipolar disorder in a high-density linkage survey in the Portuguese Island population. Am J Med Genet B Neuropsychiatr Genet. 2012 Jun; 159B(4):383-91. PMID: 22461138.
        View in: PubMed
      42. Baron DA, Pato M, Cyr RL. Treatment of adults with attention-deficit/hyperactivity disorder. J Am Osteopath Assoc. 2011 Nov; 111(11):610-4. PMID: 22104513.
        View in: PubMed
      43. Shoemaker E, Pataki C, Pato M, Pato C. Transforming residency training: a case study. Acad Psychiatry. 2011 Mar-Apr; 35(2):149-53. PMID: 21403172.
        View in: PubMed
      44. Moskvina V, Smith M, Ivanov D, Blackwood D, StClair D, Hultman C, Toncheva D, Gill M, Corvin A, O'Dushlaine C, Morris DW, Wray NR, Sullivan P, Pato C, Pato M, Sklar P, Purcell S, Holmans P, O'Donovan MC, Owen MJ, Kirov G. Genetic differences between five European populations. Hum Hered. 2010; 70(2):141-9. PMID: 20616560.
        View in: PubMed
      45. Maia BR, Soares MJ, Gomes A, Marques M, Pereira AT, Cabral A, Valente J, Bos SC, Pato M, Pocinho F, Azevedo MH, Macedo A. Perfectionism in obsessive-compulsive and eating disorders. Rev Bras Psiquiatr. 2009 Dec; 31(4):322-7. PMID: 21612022.
        View in: PubMed
      46. Soares MJ, Macedo A, Carvalho Bos S, Marques M, Maia B, Pereira AT, Gomes A, Valente J, Pato M, Azevedo MH. Perfectionism and eating attitudes in Portuguese students: a longitudinal study. Eur Eat Disord Rev. 2009 Sep-Oct; 17(5):390-8. PMID: 19308944.
        View in: PubMed
      47. Parsons TD, Kenny P, Ntuen CA, Pataki CS, Pato M, Rizzo AA, St-George C, Sugar J. Objective structured clinical interview training using a virtual human patient. Stud Health Technol Inform. 2008; 132:357-62. PMID: 18391321.
        View in: PubMed
      48. Macedo A, Soares MJ, Azevedo MH, Gomes A, Pereira AT, Maia B, Pato M. Perfectionism and eating attitudes in Portuguese university students. Eur Eat Disord Rev. 2007 Jul; 15(4):296-304. PMID: 17676700.
        View in: PubMed
      49. Wojtecki CA, Wade MJ, Pato M. Teaching interested clinicians how to develop research projects. Acad Psychiatry. 2007 Mar-Apr; 31(2):168-70. PMID: 17344460.
        View in: PubMed
      50. Eisener A, Pato M, Medeiros H, Carvalho C, Pato CN. Genetics of schizophrenia: recent advances. Psychopharmacol Bull. 2007; 40(4):168-77. PMID: 18227786.
        View in: PubMed
      51. Shavitt RG, Belotto C, Curi M, Hounie AG, Rosário-Campos MC, Diniz JB, Ferrão YA, Pato M, Miguel EC. Clinical features associated with treatment response in obsessive-compulsive disorder. Compr Psychiatry. 2006 Jul-Aug; 47(4):276-81. PMID: 16769302.
        View in: PubMed
      52. Middleton FA, Trauzzi MG, Shrimpton AE, Gentile KL, Morley CP, Medeiros H, Pato M, Pato CN. Complete maternal uniparental isodisomy of chromosome 4 in a subject with major depressive disorder detected by high density SNP genotyping arrays. Am J Med Genet B Neuropsychiatr Genet. 2006 Jan 05; 141B(1):28-32. PMID: 16331669.
        View in: PubMed
      53. Wong AH, Likhodi O, Trakalo J, Yusuf M, Sinha A, Pato CN, Pato M, Van Tol HH, Kennedy JL. Genetic and post-mortem mRNA analysis of the 14-3-3 genes that encode phosphoserine/threonine-binding regulatory proteins in schizophrenia and bipolar disorder. Schizophr Res. 2005 Oct 15; 78(2-3):137-46. PMID: 16054338.
        View in: PubMed
      54. Pato M. A day in the life of an academic psychiatrist. Michele T. Pato, M.D. Acad Psychiatry. 2005 Sep-Oct; 29(4):378-9. PMID: 16223904.
        View in: PubMed
      55. McQueen MB, Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, Abou Jamra R, Albus M, Bacanu SA, Baron M, Barrett TB, Berrettini W, Blacker D, Byerley W, Cichon S, Coryell W, Craddock N, Daly MJ, Depaulo JR, Edenberg HJ, Foroud T, Gill M, Gilliam TC, Hamshere M, Jones I, Jones L, Juo SH, Kelsoe JR, Lambert D, Lange C, Lerer B, Liu J, Maier W, Mackinnon JD, McInnis MG, McMahon FJ, Murphy DL, Nothen MM, Nurnberger JI, Pato CN, Pato M, Potash JB, Propping P, Pulver AE, Rice JP, Rietschel M, Scheftner W, Schumacher J, Segurado R, Van Steen K, Xie W, Zandi PP, Laird NM. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet. 2005 Oct; 77(4):582-95. PMID: 16175504; PMCID: PMC1275607.
      56. Middleton FA, Pato CN, Gentile KL, McGann L, Brown AM, Trauzzi M, Diab H, Morley CP, Medeiros H, Macedo A, Azevedo MH, Pato M. Gene expression analysis of peripheral blood leukocytes from discordant sib-pairs with schizophrenia and bipolar disorder reveals points of convergence between genetic and functional genomic approaches. Am J Med Genet B Neuropsychiatr Genet. 2005 Jul 05; 136B(1):12-25. PMID: 15892139.
        View in: PubMed
      57. Pato CN, Middleton FA, Gentile KL, Morley CP, Medeiros H, Macedo A, Azevedo MH, Pato M. Genetic linkage of bipolar disorder to chromosome 6q22 is a consistent finding in Portuguese subpopulations and may generalize to broader populations. Am J Med Genet B Neuropsychiatr Genet. 2005 Apr 05; 134B(1):119-21. PMID: 15704217.
        View in: PubMed
      58. Wong AH, Trakalo J, Likhodi O, Yusuf M, Macedo A, Azevedo MH, Klempan T, Pato M, Honer WG, Pato CN, Van Tol HH, Kennedy JL. Association between schizophrenia and the syntaxin 1A gene. Biol Psychiatry. 2004 Jul 01; 56(1):24-9. PMID: 15219469.
        View in: PubMed
      59. Ambrósio AM, Kennedy JL, Macciardi F, Coelho I, Soares MJ, Oliveira CR, Pato M, Pato CN. Nonparametric linkage analysis between schizophrenia and candidate genes of dopaminergic and serotonergic systems. CNS Spectr. 2004 Apr; 9(4):302-8. PMID: 15048055.
        View in: PubMed
      60. Freedman ML, Reich D, Penney KL, McDonald GJ, Mignault AA, Patterson N, Gabriel SB, Topol EJ, Smoller JW, Pato CN, Pato M, Petryshen TL, Kolonel LN, Lander ES, Sklar P, Henderson B, Hirschhorn JN, Altshuler D. Assessing the impact of population stratification on genetic association studies. Nat Genet. 2004 Apr; 36(4):388-93. PMID: 15052270.
        View in: PubMed
      61. Pato M. Taking some unnatural steps: "improvements to complex systems do not occur naturally". Acad Psychiatry. 2004; 28(4):351-3. PMID: 15673835.
        View in: PubMed
      62. Eisener AF, Pato CN, Dewan M, Pato M. From genomics to proteomics: new directions in molecular neuropsychiatry. Acta Neuropsychiatr. 2003 Dec; 15(6):388-97. PMID: 26983774.
        View in: PubMed
      63. Narendran R, Young CM, Pristach CA, Pato M, Valenti AM, Fass AR. Efficacy of clozapine in the treatment of atypical antipsychotic refractory schizophrenia: a pilot study. J Clin Psychopharmacol. 2003 Feb; 23(1):103-4. PMID: 12544385.
        View in: PubMed
      64. Pallanti S, Hollander E, Bienstock C, Koran L, Leckman J, Marazziti D, Pato M, Stein D, Zohar J. Treatment non-response in OCD: methodological issues and operational definitions. Int J Neuropsychopharmacol. 2002 Jun; 5(2):181-91. PMID: 12135542.
        View in: PubMed
      65. Pato M, Pato CN, Pauls DL. Recent findings in the genetics of OCD. J Clin Psychiatry. 2002; 63 Suppl 6:30-3. PMID: 12027117.
        View in: PubMed