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Luanda Grazette, MD

TitleAssociate Professor of Clinical Medicine
InstitutionUniversity of Southern California
DepartmentMedicine
AddressHCC 322
Health Sciences Campus
Los Angeles CA 90089-9198
Phone+1 323 442 6130
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    Collapse Biography 
    Collapse Awards and Honors
    National Institute of Health2000  - 2005K01 Mentored Faculty Development Award
    Harvard Medical SchoolPeabody Society Award

    Collapse Overview 
    Collapse Overview
    Dr. Luanda Grazette completed her undergraduate studies at the University of Alabama and went on to Harvard to earn her Medical Degree and Masters Degree in Public Health. She then completed her internship and residency at Massachusetts General Hospital in Boston followed by Fellowship training in Clinical Cardiology at Emory University. After completing her fellowship, Dr. Grazette returned to Massachusetts General Hospital for additional training in Heart Failure and Transplantation and Heart Failure Research and then remained on staff as a Physician-Scientist.

    Her experience with follow-up care of transplant patients, supervision of students and fellows, and management of pre- and post-transplant patients in critical care settings and inpatient consultation makes her a tremendous asset to USC. In addition to her clinical responsibilities, Dr. Grazette engaged in active clinical and translational research investigating the basic mechanisms of cardiac toxicity, plasticty and survival. Dr Grazette has also served as a Medical Director of Global Clinical Research for Amgen where she overseeing early and late stage clinical trials. Myocardial plasticity and the potential for recovery remain the focus of her clinical and research activities.


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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chaudhry M, Grazette L, Fong MW. Myxedema Heart Disease: A rare disease entity. Case report and brief review of the literature. Curr Hypertens Rev. 2018 Oct 01. PMID: 30277162.
      View in: PubMed
    2. Chaudhry MA, Grazette L, Yoon A, Correa A, Fong MW. Churg-Strauss Syndrome Presenting As Acute Necrotizing Eosinophilic Myocarditis. Concise review of the literature. Curr Hypertens Rev. 2018 Sep 03. PMID: 30179138.
      View in: PubMed
    3. Wolfson AM, Fong M, Grazette L, Rahman JE, Shavelle DM. Chronic heart failure management and remote haemodynamic monitoring. Heart. 2018 Aug 18. PMID: 30121633.
      View in: PubMed
    4. Wolfson AM, Grazette L, Saxon L, Nazeer H, Shavelle DM, Jermyn R. Baseline diastolic pressure gradient and pressure reduction in chronic heart failure patients implanted with the CardioMEMS™ HF sensor. ESC Heart Fail. 2018 Jun; 5(3):316-321. PMID: 29498245.
      View in: PubMed
    5. Butera BC, Grazette LP, Lawrence T, Bowdish ME, Yoon AJ. Case Report of Multiembolic Cerebrovascular Event Associated with Ramp Study Echocardiogram. Case Rep Cardiol. 2017; 2017:9072523. PMID: 29093975.
      View in: PubMed
    6. Wolfson AM, Yousefian O, Short L, O'Brien D, Talmor G, Qiu J, Yoon A, Fong M, Saxon L, Doshi R, Grazette L, Shavelle DM. Effects of pressure variation and atrial fibrillation on CardioMEMS™ HF measured pulmonary artery diastolic pressure: comparison of device-averaged and visually inspected waveforms. Physiol Meas. 2017 Jun; 38(6):1094-1103. PMID: 28493849.
      View in: PubMed
    7. McLeod J, Wu S, Grazette L, Sarcon A. Tacrolimus-Associated Dilated Cardiomyopathy in Adult Patient After Orthotopic Liver Transplant. J Investig Med High Impact Case Rep. 2017 Apr-Jun; 5(2):2324709617706087. PMID: 28508004.
      View in: PubMed
    8. Havakuk O, King KS, Grazette L, Yoon AJ, Fong M, Bregman N, Elkayam U, Kloner RA. Heart Failure-Induced Brain Injury. J Am Coll Cardiol. 2017 Mar 28; 69(12):1609-1616. PMID: 28335844.
      View in: PubMed
    9. King K, Grazette LP, Paltoo DN, McDevitt JT, Sia SK, Barrett PM, Apple FS, Gurbel PA, Weissleder R, Leeds H, Iturriaga EJ, Rao A, Adhikari B, Desvigne-Nickens P, Galis ZS, Libby P. Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research: National Heart, Lung, and Blood Institute Working Group. JACC Basic Transl Sci. 2016 Jan-Feb; 1(1-2):73-86. PMID: 26977455.
      View in: PubMed
    10. Yoon AJ, Sohn J, Grazette L, Fong MW, Bowdish ME. Pan-Cardiac Cycle Fixed Mitral Valve Opening in an LVAD Patient Presenting with Hemorrhagic Shock. Echocardiography. 2016 Apr; 33(4):644-6. PMID: 26676075.
      View in: PubMed
    11. Fung E, Fong MW, Correa AJ, Yoon AJ, Grazette LP. Fulminant eosinophilic myocarditis following ICD implantation in a patient with undisclosed nickel allergy. Int J Cardiol. 2016 Jan 15; 203:1018-9. PMID: 26630628.
      View in: PubMed
    12. Fung E, Järvelin MR, Doshi RN, Shinbane JS, Carlson SK, Grazette LP, Chang PM, Sangha RS, Huikuri HV, Peters NS. Electrocardiographic patch devices and contemporary wireless cardiac monitoring. Front Physiol. 2015; 6:149. PMID: 26074823; PMCID: PMC4444741.
    13. Chaudhry MA, Correa A, Lee C, Yoon A, Grazette L, Saremi F, Fong MW. Modern day management of giant cell myocarditis. Int J Cardiol. 2015 Jan 15; 178:82-4. PMID: 25464225.
      View in: PubMed
    14. Samelson EJ, Miller PD, Christiansen C, Daizadeh NS, Grazette L, Anthony MS, Egbuna O, Wang A, Siddhanti SR, Cheung AM, Franchimont N, Kiel DP. RANKL inhibition with denosumab does not influence 3-year progression of aortic calcification or incidence of adverse cardiovascular events in postmenopausal women with osteoporosis and high cardiovascular risk. J Bone Miner Res. 2014 Feb; 29(2):450-7. PMID: 23873632; PMCID: PMC3946983.
    15. Fong MW, Grazette L, Cesario D, Cao M, Saxon L. Treatment of ventricular tachycardia in patients with heart failure. Curr Cardiol Rep. 2011 Jun; 13(3):203-9. PMID: 21445560.
      View in: PubMed
    16. Bone HG, Bolognese MA, Yuen CK, Kendler DL, Miller PD, Yang YC, Grazette L, San Martin J, Gallagher JC. Effects of denosumab treatment and discontinuation on bone mineral density and bone turnover markers in postmenopausal women with low bone mass. J Clin Endocrinol Metab. 2011 Apr; 96(4):972-80. PMID: 21289258.
      View in: PubMed
    17. Kerkelä R, Grazette L, Yacobi R, Iliescu C, Patten R, Beahm C, Walters B, Shevtsov S, Pesant S, Clubb FJ, Rosenzweig A, Salomon RN, Van Etten RA, Alroy J, Durand JB, Force T. Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med. 2006 Aug; 12(8):908-16. PMID: 16862153.
      View in: PubMed
    18. Sosnovik DE, Schellenberger EA, Nahrendorf M, Novikov MS, Matsui T, Dai G, Reynolds F, Grazette L, Rosenzweig A, Weissleder R, Josephson L. Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle. Magn Reson Med. 2005 Sep; 54(3):718-24. PMID: 16086367.
      View in: PubMed
    19. Smith RN, Brousaides N, Grazette L, Saidman S, Semigran M, Disalvo T, Madsen J, Dec GW, Perez-Atayde AR, Collins AB. C4d deposition in cardiac allografts correlates with alloantibody. J Heart Lung Transplant. 2005 Sep; 24(9):1202-10. PMID: 16143234.
      View in: PubMed
    20. Nagoshi T, Matsui T, Aoyama T, Leri A, Anversa P, Li L, Ogawa W, del Monte F, Gwathmey JK, Grazette L, Hemmings BA, Hemmings B, Kass DA, Champion HC, Rosenzweig A. PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury. J Clin Invest. 2005 Aug; 115(8):2128-38. PMID: 16007268; PMCID: PMC1172227.
    21. Grazette LP, Rosenzweig A. Role of apoptosis in heart failure. Heart Fail Clin. 2005 Jul; 1(2):251-61. PMID: 17386850.
      View in: PubMed
    22. Grazette LP, Boecker W, Matsui T, Semigran M, Force TL, Hajjar RJ, Rosenzweig A. Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes: implications for herceptin-induced cardiomyopathy. J Am Coll Cardiol. 2004 Dec 07; 44(11):2231-8. PMID: 15582322.
      View in: PubMed
    23. Boecker W, Bernecker OY, Wu JC, Zhu X, Sawa T, Grazette L, Rosenzweig A, del Monte F, Schmidt U, Hajjar RJ. Cardiac-specific gene expression facilitated by an enhanced myosin light chain promoter. Mol Imaging. 2004 Apr; 3(2):69-75. PMID: 15296671.
      View in: PubMed
    24. Smith RN, Chang Y, Houser S, Dec GW, Grazette L. Higher frequency of high-grade rejections in cardiac allograft patients after Quilty B lesions or grade 2/4 rejections. Transplantation. 2002 Jun 27; 73(12):1928-32. PMID: 12131690.
      View in: PubMed
    25. Haq S, Choukroun G, Lim H, Tymitz KM, del Monte F, Gwathmey J, Grazette L, Michael A, Hajjar R, Force T, Molkentin JD. Differential activation of signal transduction pathways in human hearts with hypertrophy versus advanced heart failure. Circulation. 2001 Feb 06; 103(5):670-7. PMID: 11156878.
      View in: PubMed
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