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Leonardo C Clavijo, MD, PhD

Title(s)Associate Professor of Clinical Medicine
Phone+1 323 442 6130
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    Other Positions
    Title(s)Director, Interventional Cardiology Fellowship Program


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    Dr. Clavijo's clinical interests include non-surgical treatment of complex vascular disease, peripheral arterial disease, peripheral vascular disease, carotid disease and interventional cardiology. His research interests include percutaneous coronary interventions, critical limb ischemia, endovascular treatment of peripheral arterial and venous vascular disease and vascular biology.

    Dr. Clavijo earned his medical degree from Universidad Nacional de Colombia. He then went on to complete his Masters of Science in Physiology & Biophysics and Doctor of Philosophy in Physiology & Biophysics from the University of Louisville School of Medicine.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Miller JD, Lew EJ, Giovinco NA, Ochoa C, Rowe VL, Clavijo LC, Weaver F, Armstrong DG. How to Create a Hot Foot Line to Prevent Diabetes-Related Amputations: Instant Triage for Emergency Department and Inpatient Consultations. J Am Podiatr Med Assoc. 2019 Mar; 109(2):174-179. PMID: 31135194.
      View in: PubMed
    2. Dhillon AS, Narayanan MR, Tun H, Hindoyan A, Matthews R, Mehra A, Shavelle DM, Clavijo LC. In-Hospital Outcomes of Rotational Atherectomy in High-Risk Patients With Severely Calcified Left Main Coronary Artery Disease: A Single-Center Experience. J Invasive Cardiol. 2019 Apr; 31(4):101-106. PMID: 30643039.
      View in: PubMed
    3. Zhang J, Patel S, Clavijo L, Laughrun D. Successful Implementation of Extracorporeal Membrane Oxygenation Support as a Bridge to Heart-Lung Transplantation in an Eisenmenger's Syndrome Patient With Paradoxical Coronary Embolism. J Investig Med High Impact Case Rep. 2019 Jan-Dec; 7:2324709619846575. PMID: 31053036.
      View in: PubMed
    4. Kendall MR, Swadron S, Clavijo LC, Mehra AK, Hindoyan A, Matthews RV, Shavelle DM. Use of the STEMI Team for Treatment of Patients With Pulmonary Embolism: A Pilot Study. J Invasive Cardiol. 2018 10; 30(10):367-371. PMID: 30279292.
      View in: PubMed
    5. Nairooz R, Saad M, Dhillon AS, Yousaf H, Awar L, Mehra A, Matthews RV, Shavelle D, Clavijo L. Long-term outcomes of drug-eluting stents versus bare metal stents in saphenous vein graft interventions. Evidence from a meta-analysis of randomized controlled trials. Cardiovasc Revasc Med. 2018 Dec; 19(8):951-955. PMID: 30078629.
      View in: PubMed
    6. Wu S, Chai A, Arimie S, Mehra A, Clavijo L, Matthews RV, Shavelle DM. Incidence and treatment of severe primary mitral regurgitation in contemporary clinical practice. Cardiovasc Revasc Med. 2018 Dec; 19(8):960-963. PMID: 30060923.
      View in: PubMed
    7. Dhillon AS, Li S, Lewinger JP, Shavelle DM, Matthews RV, Clavijo LC, Weaver FA, Garg P. Comparison of devices used in carotid artery stenting: A vascular quality initiative analysis of commonly used carotid stents and embolic protection devices. Catheter Cardiovasc Interv. 2018 Oct 01; 92(4):743-749. PMID: 30019819.
      View in: PubMed
    8. Clavijo LC, Al-Asady N, Dhillon A, Matthews RV, Caro J, Tun H, Rowe V, Shavelle DM. Prevalence of high on-treatment (aspirin and clopidogrel) platelet reactivity in patients with critical limb ischemia. Cardiovasc Revasc Med. 2018 Jul; 19(5 Pt A):516-520. PMID: 29221961.
      View in: PubMed
    9. Clavijo LC, Dhillon A, Al-Asady N, Matthews RV, Caro J, Tun H, Rowe V, Shavelle DM. Switch to Ticagrelor in critical limb ischemia antiplatelet study (STT-CLIPS). Cardiovasc Revasc Med. 2018 Apr - May; 19(3 Pt B):319-323. PMID: 29329963.
      View in: PubMed
    10. Teixeira PG, Clavijo LC, Wilcox AG, Weaver FA. Computerized tomography angiography by direct intra-aortic low volume contrast injection in patients being evaluated for EVAR. Vascular. 2017 Oct; 25(5):451-458. PMID: 28118783.
      View in: PubMed
    11. Flores E, Lewinger JP, Rowe VL, Woo K, Weaver FA, Shavelle D, Clavijo L, Garg PK. Increased risk of mortality after lower extremity bypass in individuals with acute kidney injury in the Vascular Quality Initiative. J Vasc Surg. 2017 Apr; 65(4):1055-1061. PMID: 27865637.
      View in: PubMed
    12. Ward R, Dunn J, Clavijo L, Shavelle D, Rowe V, Woo K. Outcomes of Critical Limb Ischemia in an Urban, Safety Net Hospital Population with High WIfI Amputation Scores. Ann Vasc Surg. 2017 Jan; 38:84-89. PMID: 27546850.
      View in: PubMed
    13. Essilfie G, Shavelle DM, Tun H, Platt K, Kobayashi R, Mehra A, Matthews RV, Clavijo L, Gaglia MA. Association of elevated triglycerides and acute myocardial infarction in young Hispanics. Cardiovasc Revasc Med. 2016 Dec; 17(8):510-514. PMID: 27432210.
      View in: PubMed
    14. Clavijo LC, Cortes GA, Jolly A, Tun H, Mehra A, Gaglia MA, Shavelle D, Matthews RV. Same-day discharge after coronary stenting and femoral artery device closure: A randomized study in stable and low-risk acute coronary syndrome patients. Cardiovasc Revasc Med. 2016 Apr-May; 17(3):155-61. PMID: 27157292.
      View in: PubMed
    15. Clavijo LC, Maya J, Carlson G, Angiolillo DJ, Teng R, Caplan R, Price MJ. Platelet inhibition with ticagrelor versus clopidogrel in Hispanic patients with stable coronary artery disease with or without diabetes mellitus. Cardiovasc Revasc Med. 2015 Dec; 16(8):450-4. PMID: 26440227.
      View in: PubMed
    16. Elsayed S, Clavijo LC. Critical limb ischemia. Cardiol Clin. 2015 Feb; 33(1):37-47. PMID: 25439329.
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    17. Clavijo LC. Vascular disease. Preface. Cardiol Clin. 2015 Feb; 33(1):ix. PMID: 25439338.
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    18. Price MJ, Clavijo L, Angiolillo DJ, Carlson G, Caplan R, Teng R, Maya J. A randomised trial of the pharmacodynamic and pharmacokinetic effects of ticagrelor compared with clopidogrel in Hispanic patients with stable coronary artery disease. J Thromb Thrombolysis. 2015 Jan; 39(1):8-14. PMID: 25305090.
      View in: PubMed
    19. Azarbal A, Clavijo L, Gaglia MA. Antiplatelet therapy for peripheral arterial disease and critical limb ischemia: guidelines abound, but where are the data? J Cardiovasc Pharmacol Ther. 2015 Mar; 20(2):144-56. PMID: 25079473.
      View in: PubMed
    20. Gaglia MA, Shavelle DM, Tun H, Bhatt J, Mehra A, Matthews RV, Clavijo L. African-American patients are less likely to receive drug-eluting stents during percutaneous coronary intervention. Cardiovasc Revasc Med. 2014 Jun; 15(4):214-8. PMID: 24814420.
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    21. Gaglia MA, Clavijo L. Cardiovascular pharmacology core reviews: aspirin. J Cardiovasc Pharmacol Ther. 2013 Nov; 18(6):505-13. PMID: 24057863.
      View in: PubMed
    22. Prasad A, Zareh M, Doherty R, Gopal A, Vora H, Somma K, Mehra A, Clavijo LC, Matthews RV, Shavelle DM. Use of regadenoson for measurement of fractional flow reserve. Catheter Cardiovasc Interv. 2014 Feb 15; 83(3):369-74. PMID: 23765847.
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    23. Gopal A, Aranson N, Woo K, Clavijo L, Shavelle DM. Recalcitrant peroneal artery pseudoaneurysm in a patient with Hemophilia B. Cardiovasc Revasc Med. 2013 Nov-Dec; 14(6):359-62. PMID: 23773548.
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    24. Al-Ameri H, Clavijo L, Matthews RV, Kloner RA, Shavelle DM. Devices to treat peripheral chronic total occlusions. J Interv Cardiol. 2012 Aug; 25(4):395-403. PMID: 22564193.
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    25. Shah R, Thomson A, Atianzar K, Somma K, Mehra A, Clavijo L, Matthews RV, Shavelle DM. Percutaneous left ventricular support for high-risk PCI and cardiogenic shock: who gets what? Cardiovasc Revasc Med. 2012 Mar-Apr; 13(2):101-5. PMID: 22406055.
      View in: PubMed
    26. Shavelle DM, Clavijo L, Matthews RV. Percutaneous devices to support the left ventricle. Expert Rev Med Devices. 2011 Nov; 8(6):681-94. PMID: 22029466.
      View in: PubMed
    27. Nguyen TH, Clavijo LC, Naqvi TZ. Acute ST segment elevation during exercise stress echocardiography due to severe pulmonary hypertension. Cardiovasc Ultrasound. 2011 Jun 06; 9:18. PMID: 21645399.
      View in: PubMed
    28. Zada G, Terterov S, Russin J, Clavijo L, Giannotta S. Cerebral vasospasm and concurrent left ventricular outflow tract obstruction: requirement for modification of hyperdynamic therapy regimen. Neurocrit Care. 2010 Apr; 12(2):265-8. PMID: 19816811.
      View in: PubMed
    29. Chen SF, El-Bialy A, Matthews R, Clavijo L. Use of drug-eluting versus bare-metal stents in ST-segment elevation myocardial infarction. J Invasive Cardiol. 2009 Nov; 21(11):E206-12. PMID: 19901420.
      View in: PubMed
    30. Das P, Clavijo LC, Nanjundappa A, Dieter RS. Revascularization of carotid stenosis before cardiac surgery. Expert Rev Cardiovasc Ther. 2008 Nov; 6(10):1393-6. PMID: 19018692.
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    31. Zbinden S, Clavijo LC, Kantor B, Morsli H, Cortes GA, Andrews JA, Jang GJ, Burnett MS, Epstein SE. Interanimal variability in preexisting collaterals is a major factor determining outcome in experimental angiogenesis trials. Am J Physiol Heart Circ Physiol. 2007 Apr; 292(4):H1891-7. PMID: 17189353.
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    32. Clavijo LC, Steinberg DH, Torguson R, Kuchulakanti PK, Chu WW, Fournadjiev J, Satler LF, Kent KM, Suddath WO, Waksman R, Pichard AD. Sirolimus-eluting stents and calcified coronary lesions: clinical outcomes of patients treated with and without rotational atherectomy. Catheter Cardiovasc Interv. 2006 Dec; 68(6):873-8. PMID: 17086529.
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    33. Chu WW, Kuchulakanti PK, Torguson R, Wang B, Clavijo LC, Suddath WO, Pichard AD, Satler LF, Kent KM, Waksman R. Comparison of clinical outcomes of overlapping sirolimus- versus paclitaxel-eluting stents in patients undergoing percutaneous coronary intervention. Am J Cardiol. 2006 Dec 15; 98(12):1563-6. PMID: 17145210.
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    34. Javaid A, Chu WW, Cheneau E, Clavijo LC, Satler LF, Kent KM, Weissman NJ, Pichard AD, Waksman R. Comparison of paclitaxel-eluting stent and sirolimus-eluting stent expansion at incremental delivery pressures. Cardiovasc Revasc Med. 2006 Oct-Dec; 7(4):208-11. PMID: 17174865.
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    35. Chu WW, Kuchulakanti PK, Torguson R, Wang B, Clavijo LC, Suddath WO, Pichard AD, Satler LF, Kent KM, Waksman R. Impact of three or more sirolimus-eluting stents versus paclitaxel-eluting stents on clinical outcomes in patients undergoing percutaneous coronary intervention. Catheter Cardiovasc Interv. 2006 Jul; 68(1):62-6. PMID: 16755592.
      View in: PubMed
    36. Chu WW, Kuchulakanti PK, Wang B, Torguson R, Clavijo LC, Pichard AD, Suddath WO, Satler LF, Kent KM, Waksman R. Bivalirudin versus unfractionated heparin in patients undergoing percutaneous coronary intervention after acute myocardial infarction. Cardiovasc Revasc Med. 2006 Jul-Sep; 7(3):132-5. PMID: 16945819.
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    37. Kuchulakanti PK, Chu WW, Torguson R, Clavijo L, Wolfram R, Mishra S, Xue Z, Gevorkian N, Suddath WO, Satler LF, Kent KM, Pichard AD, Waksman R. Sirolimus-eluting stents versus Paclitaxel-eluting stents in the treatment of coronary artery disease in patients with diabetes mellitus. Am J Cardiol. 2006 Jul 15; 98(2):187-92. PMID: 16828590.
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    38. Chu WW, Kuchulakanti PK, Torguson R, Wang B, Clavijo LC, Suddath WO, Pichard AD, Satler LF, Kent KM, Waksman R. Impact of overlapping drug-eluting stents in patients undergoing percutaneous coronary intervention. Catheter Cardiovasc Interv. 2006 Apr; 67(4):595-9. PMID: 16532495.
      View in: PubMed
    39. Chu WW, Kuchulakanti PK, Wang B, Clavijo LC, Suddath WO, Pichard AD, Satler LF, Kent KM, Waksman R. Efficacy of sirolimus-eluting stents as compared to paclitaxel-eluting stents for saphenous vein graft intervention. J Interv Cardiol. 2006 Apr; 19(2):121-5. PMID: 16650239.
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    40. Kuchulakanti PK, Chu WW, Torguson R, Ohlmann P, Rha SW, Clavijo LC, Kim SW, Bui A, Gevorkian N, Xue Z, Smith K, Fournadjieva J, Suddath WO, Satler LF, Pichard AD, Kent KM, Waksman R. Correlates and long-term outcomes of angiographically proven stent thrombosis with sirolimus- and paclitaxel-eluting stents. Circulation. 2006 Feb 28; 113(8):1108-13. PMID: 16490815.
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    41. Clavijo LC, Pinto TL, Kuchulakanti PK, Torguson R, Chu WW, Satler LF, Kent KM, Suddath WO, Waksman R, Pichard AD. Effect of a rapid intra-arterial infusion of dextrose 5% prior to coronary angiography on frequency of contrast-induced nephropathy in high-risk patients. Am J Cardiol. 2006 Apr 01; 97(7):981-3. PMID: 16563900.
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    42. Kuchulakanti PK, Torguson R, Chu WW, Canos DA, Rha SW, Clavijo L, Deible R, Gevorkian N, Suddath WO, Satler LF, Kent KM, Pichard AD, Waksman R. Impact of chronic renal insufficiency on clinical outcomes in patients undergoing percutaneous coronary intervention with sirolimus-eluting stents versus bare metal stents. Am J Cardiol. 2006 Mar 15; 97(6):792-7. PMID: 16516578.
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    43. Chu WW, Kuchulakanti PK, Rha SW, GebreEyesus A, Aggrey G, Torguson R, Wang B, Xue Z, Clavijo LC, Suddath WO, Pichard AD, Satler LF, Kent KM, Waksman R. Impact of three or more versus a single sirolimus-eluting stent on outcomes in patients who undergo percutaneous coronary intervention. Am J Cardiol. 2006 Mar 01; 97(5):606-10. PMID: 16490422.
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    44. Clavijo LC, Pinto TL, Kuchulakanti PK, Torguson R, Chu WW, Satler LF, Kent KM, Suddath WO, Pichard AD, Waksman R. Metabolic syndrome in patients with acute myocardial infarction is associated with increased infarct size and in-hospital complications. Cardiovasc Revasc Med. 2006 Jan-Mar; 7(1):7-11. PMID: 16513517.
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    45. Kuchulakanti P, Wolfram R, Torguson R, Rha SW, Cheneau E, Clavijo L, Chu WW, Pinnow EE, Canos D, Satler LF, Suddath WO, Pichard AD, Kent KM, Waksman R. Bivalirudin compared with IIb/IIIa inhibitors in patients with in-stent restenosis undergoing intracoronary brachytherapy. Cardiovasc Revasc Med. 2005 Oct-Dec; 6(4):154-9. PMID: 16326376.
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    46. Pakala R, Stabile E, Jang GJ, Clavijo L, Waksman R. Rapamycin attenuates atherosclerotic plaque progression in apolipoprotein E knockout mice: inhibitory effect on monocyte chemotaxis. J Cardiovasc Pharmacol. 2005 Oct; 46(4):481-6. PMID: 16160601.
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    47. Burnett MS, Lee CW, Kinnaird TD, Stabile E, Durrani S, Dullum MK, Devaney JM, Fishman C, Stamou S, Canos D, Zbinden S, Clavijo LC, Jang GJ, Andrews JA, Zhu J, Epstein SE. The potential role of resistin in atherogenesis. Atherosclerosis. 2005 Oct; 182(2):241-8. PMID: 16159596.
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    48. Kuchulakanti PK, Torguson R, Canos D, Rha SW, Chu WW, Clavijo L, Deible R, Gevorkian N, Suddath WO, Satler LF, Kent KM, Pichard AD, Waksman R. Impact of treatment of coronary artery disease with sirolimus-eluting stents on outcomes of diabetic and nondiabetic patients. Am J Cardiol. 2005 Oct 15; 96(8):1100-6. PMID: 16214445.
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    49. Mofrad PS, Weigold G, Clavijo LC. Sudden cardiac death in athlete with anomalous single coronary artery. Cardiovasc Revasc Med. 2005 Apr-Jun; 6(2):89-90. PMID: 16459367.
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    50. Clavijo LC, Yar O, Kuchulakanti P, Chu WW, Suddath WO, Satler LF, Kent KM, Waksman R, Pichard AD. MRI evaluation of a coronary artery perforation. Cardiovasc Revasc Med. 2005 Jan-Mar; 6(1):44-5. PMID: 16263356.
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    51. Clavijo LC, Kuchulakanti P, Chu WW, Weigold G, Pichard AD, Waksman R, Boyce SW, Satler LF, Kent KM. "Hybrid" approach for the treatment of a giant left main coronary artery aneurysm. Cardiovasc Radiat Med. 2004 Jul-Sep; 5(3):153-4. PMID: 15721852.
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    52. Epstein SE, Stabile E, Kinnaird T, Lee CW, Clavijo L, Burnett MS. Janus phenomenon: the interrelated tradeoffs inherent in therapies designed to enhance collateral formation and those designed to inhibit atherogenesis. Circulation. 2004 Jun 15; 109(23):2826-31. PMID: 15197154.
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    53. Guardiola JJ, Matheson PJ, Clavijo LC, Wilson MA, Fletcher EC. Hypercoagulability in patients with obstructive sleep apnea. Sleep Med. 2001 Nov; 2(6):517-23. PMID: 14592267.
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    54. Clavijo LC, Carter MB, Matheson PJ, Wilson MA, Wead WB, Garrison RN. PAF increases vascular permeability without increasing pulmonary arterial pressure in the rat. J Appl Physiol (1985). 2001 Jan; 90(1):261-8. PMID: 11133918.
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    55. Clavijo LC, Carter MB, Matheson PJ, Wills-Frank LA, Wilson MA, Wead WB, Garrison RN. Platelet-activating factor and bacteremia-induced pulmonary hypertension. J Surg Res. 2000 Feb; 88(2):173-80. PMID: 10644485.
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    56. MarĂ­n CM, Segura JL, Bern C, Freedman DS, Guillermo Lescano A, Benavente LE, Cordero LG, Clavijo L, Gilman JB. Seasonal change in nutritional status among young children in an urban shanty town in Peru. Trans R Soc Trop Med Hyg. 1996 Jul-Aug; 90(4):442-5. PMID: 8882202.
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