John Paul Murad

Title(s)Assistant Professor of Research Medicine
SchoolKeck School of Medicine of Usc
Address1450 Biggy Street
Health Sciences Campus
Los Angeles CA 90033
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. PSCA-CAR T cell therapy in metastatic castration-resistant prostate cancer: a phase 1 trial. Nat Med. 2024 Jun; 30(6):1636-1644. Dorff TB, Blanchard MS, Adkins LN, Luebbert L, Leggett N, Shishido SN, Macias A, Del Real MM, Dhapola G, Egelston C, Murad JP, Rosa R, Paul J, Chaudhry A, Martirosyan H, Gerdts E, Wagner JR, Stiller T, Tilakawardane D, Pal S, Martinez C, Reiter RE, Budde LE, D'Apuzzo M, Kuhn P, Pachter L, Forman SJ, Priceman SJ. PMID: 38867077; PMCID: PMC11186768.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsCTClinical Trials
    2. Nonsignaling extracellular spacer regulates tumor antigen selectivity of CAR T cells. Mol Ther Oncol. 2024 Jun 20; 32(2):200789. Kennewick KT, Yamaguchi Y, Gibson J, Gerdts EA, Jeang B, Tilakawardane D, Murad JP, Chang WC, Wright SL, Thiel MS, Forman SJ, Stern LA, Priceman SJ. PMID: 38939825; PMCID: PMC11208731.
      View in: PubMed   Mentions:
    3. Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting. Nat Commun. 2023 08 07; 14(1):4737. Lee EHJ, Murad JP, Christian L, Gibson J, Yamaguchi Y, Cullen C, Gumber D, Park AK, Young C, Monroy I, Yang J, Stern LA, Adkins LN, Dhapola G, Gittins B, Chang WC, Martinez C, Woo Y, Cristea M, Rodriguez-Rodriguez L, Ishihara J, Lee JK, Forman SJ, Wang LD, Priceman SJ. PMID: 37550294; PMCID: PMC10406808.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    4. Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting. bioRxiv. 2023 Jan 07. Jun Lee EH, Cullen C, Murad JP, Gumber D, Park AK, Yang J, Stern LA, Adkins LN, Dhapola G, Gittins B, Chung-Chang W, Martinez C, Woo Y, Cristea M, Rodriguez-Rodriguez L, Ishihara J, Lee JK, Forman SJ, Wang LD, Priceman SJ. PMID: 36711615; PMCID: PMC9881930.
      View in: PubMed   Mentions:
    5. Enhanced intratumoural activity of CAR T cells engineered to produce immunomodulators under photothermal control. Nat Biomed Eng. 2021 11; 5(11):1348-1359. Miller IC, Zamat A, Sun LK, Phuengkham H, Harris AM, Gamboa L, Yang J, Murad JP, Priceman SJ, Kwong GA. PMID: 34385695; PMCID: PMC8791016.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    6. Pre-conditioning modifies the TME to enhance solid tumor CAR T cell efficacy and endogenous protective immunity. Mol Ther. 2021 07 07; 29(7):2335-2349. Murad JP, Tilakawardane D, Park AK, Lopez LS, Young CA, Gibson J, Yamaguchi Y, Lee HJ, Kennewick KT, Gittins BJ, Chang WC, Tran CP, Martinez C, Wu AM, Reiter RE, Dorff TB, Forman SJ, Priceman SJ. PMID: 33647456; PMCID: PMC8261088.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    7. Effective combination immunotherapy using oncolytic viruses to deliver CAR targets to solid tumors. Sci Transl Med. 2020 09 02; 12(559). Park AK, Fong Y, Kim SI, Yang J, Murad JP, Lu J, Jeang B, Chang WC, Chen NG, Thomas SH, Forman SJ, Priceman SJ. PMID: 32878978; PMCID: PMC9126033.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    8. Effective Targeting of TAG72+ Peritoneal Ovarian Tumors via Regional Delivery of CAR-Engineered T Cells. Front Immunol. 2018; 9:2268. Murad JP, Kozlowska AK, Lee HJ, Ramamurthy M, Chang WC, Yazaki P, Colcher D, Shively J, Cristea M, Forman SJ, Priceman SJ. PMID: 30510550; PMCID: PMC6254427.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    9. Regional Delivery of Chimeric Antigen Receptor-Engineered T Cells Effectively Targets HER2+ Breast Cancer Metastasis to the Brain. Clin Cancer Res. 2018 01 01; 24(1):95-105. Priceman SJ, Tilakawardane D, Jeang B, Aguilar B, Murad JP, Park AK, Chang WC, Ostberg JR, Neman J, Jandial R, Portnow J, Forman SJ, Brown CE. PMID: 29061641; PMCID: PMC7685198.
      View in: PubMed   Mentions: 153     Fields:    Translation:HumansAnimalsCells
    10. Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA+ metastatic prostate cancer. Oncoimmunology. 2018; 7(2):e1380764. Priceman SJ, Gerdts EA, Tilakawardane D, Kennewick KT, Murad JP, Park AK, Jeang B, Yamaguchi Y, Yang X, Urak R, Weng L, Chang WC, Wright S, Pal S, Reiter RE, Wu AM, Brown CE, Forman SJ. PMID: 29308300; PMCID: PMC5749625.
      View in: PubMed   Mentions: 77     Fields:    
    11. Human brain metastatic stroma attracts breast cancer cells via chemokines CXCL16 and CXCL12. NPJ Breast Cancer. 2017; 3:6. Chung B, Esmaeili AA, Gopalakrishna-Pillai S, Murad JP, Andersen ES, Kumar Reddy N, Srinivasan G, Armstrong B, Chu C, Kim Y, Tong T, Waisman J, Yim JH, Badie B, Lee PP. PMID: 28649646; PMCID: PMC5460196.
      View in: PubMed   Mentions: 37  
    12. Antigen-specific inhibition of high-avidity T cell target lysis by low-avidity T cells via trogocytosis. Cell Rep. 2014 Aug 07; 8(3):871-882. Chung B, Stuge TB, Murad JP, Beilhack G, Andersen E, Armstrong BD, Weber JS, Lee PP. PMID: 25088413; PMCID: PMC4174572.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    13. Current and experimental antibody-based therapeutics: insights, breakthroughs, setbacks and future directions. Curr Mol Med. 2013 Jan; 13(1):165-78. Murad JP, Lin OA, Espinosa EV, Khasawneh FT. PMID: 22834842.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    14. A novel antibody targeting the ligand binding domain of the thromboxane A₂ receptor exhibits antithrombotic properties in vivo. Biochem Biophys Res Commun. 2012 May 11; 421(3):456-61. Murad JP, Espinosa EV, Ting HJ, McClure D, Khasawneh FT. PMID: 22503974.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    15. Mouse transient receptor potential channel 6: role in hemostasis and thrombogenesis. Biochem Biophys Res Commun. 2012 Jan 13; 417(2):853-6. Paez Espinosa EV, Murad JP, Ting HJ, Khasawneh FT. PMID: 22206677.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    16. Characterization of the in vivo antiplatelet activity of the antihypertensive agent losartan. J Cardiovasc Pharmacol Ther. 2012 Sep; 17(3):308-14. Murad JP, Espinosa EV, Ting HJ, Khasawneh FT. PMID: 22123197.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    17. Aspirin: pharmacology and clinical applications. Thrombosis. 2012; 2012:173124. Paez Espinosa EV, Murad JP, Khasawneh FT. PMID: 22195279; PMCID: PMC3236360.
      View in: PubMed   Mentions: 23  
    18. Thromboxane A2 receptor: biology and function of a peculiar receptor that remains resistant for therapeutic targeting. J Cardiovasc Pharmacol Ther. 2012 Sep; 17(3):248-59. Ting HJ, Murad JP, Espinosa EV, Khasawneh FT. PMID: 22064668.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    19. The C-terminal segment of the second extracellular loop of the thromboxane A2 receptor plays an important role in platelet aggregation. Biochem Pharmacol. 2012 Jan 01; 83(1):88-96. Murad JP, Espinosa EV, Ting HJ, Khasawneh FT. PMID: 22008592.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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