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    John D. Van Horn, PhD

    TitleAssociate Professor of Neurology
    SchoolKeck School of Medicine of USC
    DepartmentNeurology
    Address2025 Zonal Avenue
    Health Sciences Campus
    Los Angeles California 90033
    Phone+1 323 442 7246
    vCardDownload vCard
      Other Positions
      TitleDirector of Education, USC Institute of Neuroimaging and Informatics


      Collapse Overview 

      Collapse Biography 
      Collapse Education and Training
      Eastern Washington University, Cheney, WABA06/1989Psychology
      University of London, London, EnglandPh.D.06/1992Psychology
      Univesity of Maryland, College Park, MDM.Eng.06/2000Engineering

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      Collapse Required Scholarly Project Mentor

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Gupta A, Mayer EA, Acosta JR, Hamadani K, Torgerson C, van Horn JD, Chang L, Naliboff B, Tillisch K, Labus JS. Early adverse life events are associated with altered brain network architecture in a sex- dependent manner. Neurobiol Stress. 2017 Dec; 7:16-26. PMID: 28239631.
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      2. Van Horn J, Bhattrai A, Irimia A. Multimodal Imaging of Neurometabolic Pathology due to Traumatic Brain Injury. Trends Neurosci. 2016 Dec 09. PMID: 27939821.
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      3. Wang B, Prastawa M, Irimia A, Saha A, Liu W, Goh SY, Vespa PM, Van Horn J, Gerig G. Modeling 4D Pathological Changes by Leveraging Normative Models. Comput Vis Image Underst. 2016 Oct; 151:3-13. PMID: 27818606.
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      4. Leng Y, Shi Y, Yu Q, Van Horn J, Tang H, Li J, Xu W, Ge X, Tang Y, Han Y, Zhang D, Xiao M, Zhang H, Pang Z, Toga AW, Liu S. Phenotypic and Genetic Correlations Between the Lobar Segments of the Inferior Fronto-occipital Fasciculus and Attention. Sci Rep. 2016; 6:33015. PMID: 27597294.
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      5. Dinov ID, Heavner B, Tang M, Glusman G, Chard K, Darcy M, Madduri R, Pa J, Spino C, Kesselman C, Foster I, Deutsch EW, Price ND, Van Horn J, Ames J, Clark K, Hood L, Hampstead BM, Dauer W, Toga AW. Predictive Big Data Analytics: A Study of Parkinson's Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete Observations. PLoS One. 2016; 11(8):e0157077. PMID: 27494614.
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      6. Van Horn J. Opinion: Big data biomedicine offers big higher education opportunities. Proc Natl Acad Sci U S A. 2016 Jun 7; 113(23):6322-4. PMID: 27274038.
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      7. Martin RM, Wright MJ, Lutkenhoff ES, Ellingson BM, Van Horn J, Tubi M, Alger JR, McArthur DL, Vespa PM. Traumatic hemorrhagic brain injury: impact of location and resorption on cognitive outcome. J Neurosurg. 2017 Mar; 126(3):796-804. PMID: 27231979.
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      8. Irimia A, Van Horn J. Scale-Dependent Variability and Quantitative Regimes in Graph-Theoretic Representations of Human Cortical Networks. Brain Connect. 2016 Mar; 6(2):152-63. PMID: 26596775.
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      9. Chen C, Van Horn J. Developmental neurogenetics and multimodal neuroimaging of sex differences in autism. Brain Imaging Behav. 2016 Jan 19. PMID: 26781567.
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      10. Eickhoff S, Nichols TE, Van Horn J, Turner JA. Sharing the wealth: Neuroimaging data repositories. Neuroimage. 2016 Jan 1; 124(Pt B):1065-8. PMID: 26574120.
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      11. Irimia A, Torgerson CM, Goh SY, Van Horn J. Statistical estimation of physiological brain age as a descriptor of senescence rate during adulthood. Brain Imaging Behav. 2015 Dec; 9(4):678-89. PMID: 25376330.
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      12. Irimia A, Van Horn J. Functional neuroimaging of traumatic brain injury: advances and clinical utility. Neuropsychiatr Dis Treat. 2015; 11:2355-65. PMID: 26396520.
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      13. Fan Q, Witzel T, Nummenmaa A, Van Dijk KR, Van Horn J, Drews MK, Somerville LH, Sheridan MA, Santillana RM, Snyder J, Hedden T, Shaw EE, Hollinshead MO, Renvall V, Zanzonico R, Keil B, Cauley S, Polimeni JR, Tisdall D, Buckner RL, Wedeen VJ, Wald LL, Toga AW, Rosen BR. MGH-USC Human Connectome Project datasets with ultra-high b-value diffusion MRI. Neuroimage. 2016 Jan 1; 124(Pt B):1108-14. PMID: 26364861.
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      14. Brown JA, Van Horn J. Connected brains and minds-The UMCD repository for brain connectivity matrices. Neuroimage. 2016 Jan 1; 124(Pt B):1238-41. PMID: 26311606.
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      15. Labus JS, Van Horn J, Gupta A, Alaverdyan M, Torgerson C, Ashe-McNalley C, Irimia A, Hong JY, Naliboff B, Tillisch K, Mayer EA. Multivariate morphological brain signatures predict patients with chronic abdominal pain from healthy control subjects. Pain. 2015 Aug; 156(8):1545-54. PMID: 25906347.
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      16. Toga AW, Foster I, Kesselman C, Madduri R, Chard K, Deutsch EW, Price ND, Glusman G, Heavner BD, Dinov ID, Ames J, Van Horn J, Kramer R, Hood L. Big biomedical data as the key resource for discovery science. J Am Med Inform Assoc. 2015 Nov; 22(6):1126-31. PMID: 26198305.
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      17. Cohen MS, Hillyard SA, Galler JR, Neville HJ, Rasenick MM, Reeves AJ, Van Horn J. Opinion: Advancing neuroscience interactions with Cuba. Proc Natl Acad Sci U S A. 2015 May 12; 112(19):5859-61. PMID: 25883271.
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      18. Torgerson CM, Quinn C, Dinov I, Liu Z, Petrosyan P, Pelphrey K, Haselgrove C, Kennedy DN, Toga AW, Van Horn J. Interacting with the National Database for Autism Research (NDAR) via the LONI Pipeline workflow environment. Brain Imaging Behav. 2015 Mar; 9(1):89-103. PMID: 25666423.
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      19. Van Horn J, Pelphrey KA. Neuroimaging of the developing brain. Brain Imaging Behav. 2015 Mar; 9(1):1-4. PMID: 25724689.
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      20. Gupta A, Mayer EA, Sanmiguel CP, Van Horn J, Woodworth D, Ellingson BM, Fling C, Love A, Tillisch K, Labus JS. Patterns of brain structural connectivity differentiate normal weight from overweight subjects. Neuroimage Clin. 2015; 7:506-17. PMID: 25737959.
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      21. McEligot AJ, Behseta S, Cuajungco MP, Van Horn J, Toga AW. Wrangling Big Data Through Diversity, Research Education and Partnerships. Calif J Health Promot. 2015; 13(3):vi-ix. PMID: 27257409.
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      22. Goh SY, Irimia A, Torgerson CM, Tubi MA, Real CR, Hanley DF, Martin NA, Vespa PM, Van Horn J. Longitudinal quantification and visualization of intracerebral haemorrhage using multimodal magnetic resonance and diffusion tensor imaging. Brain Inj. 2015; 29(4):438-45. PMID: 25518865.
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      23. Torgerson CM, Van Horn J. A case study in connectomics: the history, mapping, and connectivity of the claustrum. Front Neuroinform. 2014; 8:83. PMID: 25426062.
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      24. Irimia A, Van Horn J. Epileptogenic focus localization in treatment-resistant post-traumatic epilepsy. J Clin Neurosci. 2015 Apr; 22(4):627-31. PMID: 25542591.
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      25. Torgerson CM, Irimia A, Goh SY, Van Horn J. The DTI connectivity of the human claustrum. Hum Brain Mapp. 2015 Mar; 36(3):827-38. PMID: 25339630.
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      26. Van Horn J, Toga AW. Human neuroimaging as a "Big Data" science. Brain Imaging Behav. 2014 Jun; 8(2):323-31. PMID: 24113873.
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      27. Van Horn J, Bowman I, Joshi SH, Greer V. Graphical neuroimaging informatics: application to Alzheimer's disease. Brain Imaging Behav. 2014 Jun; 8(2):300-10. PMID: 24203652.
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      28. Van Horn J. Neuroimaging and genetics in aging and age-related disease. Brain Imaging Behav. 2014 Jun; 8(2):141-2. PMID: 24623094.
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      29. Dinov ID, Petrosyan P, Liu Z, Eggert P, Zamanyan A, Torri F, Macciardi F, Hobel S, Moon SW, Sung YH, Jiang Z, Labus J, Kurth F, Ashe-McNalley C, Mayer E, Vespa PM, Van Horn J, Toga AW. The perfect neuroimaging-genetics-computation storm: collision of petabytes of data, millions of hardware devices and thousands of software tools. Brain Imaging Behav. 2014 Jun; 8(2):311-22. PMID: 23975276.
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      30. Irimia A, Goh SY, Torgerson CM, Vespa P, Van Horn J. Structural and connectomic neuroimaging for the personalized study of longitudinal alterations in cortical shape, thickness and connectivity after traumatic brain injury. J Neurosurg Sci. 2014 Sep; 58(3):129-44. PMID: 24844173.
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      31. Dinov ID, Petrosyan P, Liu Z, Eggert P, Hobel S, Vespa P, Woo Moon S, Van Horn J, Franco J, Toga AW. High-throughput neuroimaging-genetics computational infrastructure. Front Neuroinform. 2014; 8:41. PMID: 24795619.
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      32. Wang B, Liu W, Prastawa M, Irimia A, Vespa PM, van Horn JD, Fletcher PT, Gerig G. 4D ACTIVE CUT: AN INTERACTIVE TOOL FOR PATHOLOGICAL ANATOMY MODELING. Proc IEEE Int Symp Biomed Imaging. 2014 Apr; 2014:529-532. PMID: 25356193.
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      33. Irimia A, Van Horn J. Systematic network lesioning reveals the core white matter scaffold of the human brain. Front Hum Neurosci. 2014; 8:51. PMID: 24574993.
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      34. Wang B, Prastawa M, Irimia A, Chambers MC, Sadeghi N, Vespa PM, van Horn JD, Gerig G. ANALYZING IMAGING BIOMARKERS FOR TRAUMATIC BRAIN INJURY USING 4D MODELING OF LONGITUDINAL MRI. Proc IEEE Int Symp Biomed Imaging. 2013 Dec 31; 2013:1392-1395. PMID: 24443697.
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      35. Frohlich J, Van Horn J. Reviewing the ketamine model for schizophrenia. J Psychopharmacol. 2014 Apr; 28(4):287-302. PMID: 24257811.
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      36. Lou Y, Irimia A, Vela PA, Chambers MC, Van Horn J, Vespa PM, Tannenbaum AR. Multimodal deformable registration of traumatic brain injury MR volumes via the Bhattacharyya distance. IEEE Trans Biomed Eng. 2013 Sep; 60(9):2511-20. PMID: 23962986.
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      37. Irimia A, Goh SY, Torgerson CM, Stein NR, Chambers MC, Vespa PM, Van Horn J. Electroencephalographic inverse localization of brain activity in acute traumatic brain injury as a guide to surgery, monitoring and treatment. Clin Neurol Neurosurg. 2013 Oct; 115(10):2159-65. PMID: 24011495.
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      38. Irimia A, Goh SY, Torgerson CM, Chambers MC, Kikinis R, Van Horn J. Forward and inverse electroencephalographic modeling in health and in acute traumatic brain injury. Clin Neurophysiol. 2013 Nov; 124(11):2129-45. PMID: 23746499.
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      39. Torgerson CM, Irimia A, Leow AD, Bartzokis G, Moody TD, Jennings RG, Alger JR, Van Horn J, Altshuler LL. DTI tractography and white matter fiber tract characteristics in euthymic bipolar I patients and healthy control subjects. Brain Imaging Behav. 2013 Jun; 7(2):129-39. PMID: 23070746.
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      40. Wang B, Prastawa M, Saha A, Awate SP, Irimia A, Chambers MC, Vespa PM, Van Horn J, Pascucci V, Gerig G. Modeling 4D Changes in Pathological Anatomy using Domain Adaptation: Analysis of TBI Imaging using a Tumor Database. Multimodal Brain Image Anal (2013). 2013; 8159:31-39. PMID: 25346953.
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      41. Brown JA, Rudie JD, Bandrowski A, Van Horn J, Bookheimer SY. The UCLA multimodal connectivity database: a web-based platform for brain connectivity matrix sharing and analysis. Front Neuroinform. 2012; 6:28. PMID: 23226127.
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      42. Van Horn J, Gazzaniga MS. Why share data? Lessons learned from the fMRIDC. Neuroimage. 2013 Nov 15; 82:677-82. PMID: 23160115.
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      43. Colby JB, Smith L, O'Connor MJ, Bookheimer SY, Van Horn J, Sowell ER. White matter microstructural alterations in children with prenatal methamphetamine/polydrug exposure. Psychiatry Res. 2012 Nov 30; 204(2-3):140-8. PMID: 23149028.
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      44. Irimia A, Van Horn J. The structural, connectomic and network covariance of the human brain. Neuroimage. 2013 Feb 1; 66:489-99. PMID: 23116816.
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      45. Irimia A, Wang B, Aylward SR, Prastawa MW, Pace DF, Gerig G, Hovda DA, Kikinis R, Vespa PM, Van Horn J. Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction. Neuroimage Clin. 2012; 1(1):1-17. PMID: 24179732.
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      46. Toga AW, Clark KA, Thompson PM, Shattuck DW, Van Horn J. Mapping the human connectome. Neurosurgery. 2012 Jul; 71(1):1-5. PMID: 22705717.
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      47. Van Horn J, Irimia A, Torgerson CM, Chambers MC, Kikinis R, Toga AW. Mapping connectivity damage in the case of Phineas Gage. PLoS One. 2012; 7(5):e37454. PMID: 22616011.
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      48. Bowman I, Joshi SH, Van Horn J. Visual systems for interactive exploration and mining of large-scale neuroimaging data archives. Front Neuroinform. 2012; 6:11. PMID: 22536181.
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      49. Wang B, Prastawa M, Irimia A, Chambers MC, Vespa PM, Van Horn J, Gerig G. A Patient-Specific Segmentation Framework for Longitudinal MR Images of Traumatic Brain Injury. Proc SPIE Int Soc Opt Eng. 2012 Mar 23; 8314:831402. PMID: 24465115.
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      50. Irimia A, Chambers MC, Torgerson CM, Filippou M, Hovda DA, Alger JR, Gerig G, Toga AW, Vespa PM, Kikinis R, Van Horn J. Patient-tailored connectomics visualization for the assessment of white matter atrophy in traumatic brain injury. Front Neurol. 2012; 3:10. PMID: 22363313.
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      51. Irimia A, Chambers MC, Torgerson CM, Van Horn J. Circular representation of human cortical networks for subject and population-level connectomic visualization. Neuroimage. 2012 Apr 2; 60(2):1340-51. PMID: 22305988.
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      52. Jennings RG, Van Horn J. Publication bias in neuroimaging research: implications for meta-analyses. Neuroinformatics. 2012 Jan; 10(1):67-80. PMID: 21643733.
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      53. Wang B, Prastawa M, Awate SP, Irimia A, Chambers MC, Vespa PM, van Horn JD, Gerig G. SEGMENTATION OF SERIAL MRI OF TBI PATIENTS USING PERSONALIZED ATLAS CONSTRUCTION AND TOPOLOGICAL CHANGE ESTIMATION. Proc IEEE Int Symp Biomed Imaging. 2012; 1152-1155. PMID: 23999192.
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      54. Toga AW, Dinov ID, Thompson PM, Woods RP, Van Horn J, Shattuck DW, Parker DS. The Center for Computational Biology: resources, achievements, and challenges. J Am Med Inform Assoc. 2012 Mar-Apr; 19(2):202-6. PMID: 22081221.
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      55. Irimia A, Chambers MC, Alger JR, Filippou M, Prastawa MW, Wang B, Hovda DA, Gerig G, Toga AW, Kikinis R, Vespa PM, Van Horn J. Comparison of acute and chronic traumatic brain injury using semi-automatic multimodal segmentation of MR volumes. J Neurotrauma. 2011 Nov; 28(11):2287-306. PMID: 21787171.
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      56. Irimia A, Van Horn J, Halgren E. Source cancellation profiles of electroencephalography and magnetoencephalography. Neuroimage. 2012 Feb 1; 59(3):2464-74. PMID: 21959078.
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      57. Joshi SH, Marquina AL, Osher SJ, Dinov I, Toga AW, Van Horn J. FAST EDGE-FILTERED IMAGE UPSAMPLING. Proc Int Conf Image Proc. 2011 Sep 14; 1165-1168. PMID: 22323066.
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      58. Dinov ID, Torri F, Macciardi F, Petrosyan P, Liu Z, Zamanyan A, Eggert P, Pierce J, Genco A, Knowles JA, Clark AP, Van Horn J, Ames J, Kesselman C, Toga AW. Applications of the pipeline environment for visual informatics and genomics computations. BMC Bioinformatics. 2011; 12:304. PMID: 21791102.
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      59. Sayo A, Jennings RG, Van Horn J. Study factors influencing ventricular enlargement in schizophrenia: a 20 year follow-up meta-analysis. Neuroimage. 2012 Jan 2; 59(1):154-67. PMID: 21787868.
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      60. Joshi SH, Bowman I, Toga AW, Van Horn J. BRAIN PATTERN ANALYSIS OF CORTICAL VALUED DISTRIBUTIONS. Proc IEEE Int Symp Biomed Imaging. 2011 Mar 30; 1117-1120. PMID: 21743844.
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      61. Niethammer M, Hart GL, Pace DF, Vespa PM, Irimia A, Van Horn J, Aylward SR. Geometric metamorphosis. Med Image Comput Comput Assist Interv. 2011; 14(Pt 2):639-46. PMID: 21995083.
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      62. Joshi SH, Bowman I, Van Horn J. Large-scale Neuroanatomical Visualization Using a Manifold Embedding Approach. Proc IEEE Symp Vis Anal Sci Technol. 2010 Dec 10; 2010(25-26 Oct. 2010):237. PMID: 21318096.
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      63. Thomason ME, Dennis EL, Joshi AA, Joshi SH, Dinov ID, Chang C, Henry ML, Johnson RF, Thompson PM, Toga AW, Glover GH, Van Horn J, Gotlib IH. Resting-state fMRI can reliably map neural networks in children. Neuroimage. 2011 Mar 1; 55(1):165-75. PMID: 21134471.
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      64. Lederman C, Joshi A, Dinov I, Vese L, Toga A, Van Horn J. The generation of tetrahedral mesh models for neuroanatomical MRI. Neuroimage. 2011 Mar 1; 55(1):153-64. PMID: 21073968.
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      65. Dinov I, Lozev K, Petrosyan P, Liu Z, Eggert P, Pierce J, Zamanyan A, Chakrapani S, Van Horn J, Parker DS, Magsipoc R, Leung K, Gutman B, Woods R, Toga A. Neuroimaging study designs, computational analyses and data provenance using the LONI pipeline. PLoS One. 2010; 5(9). PMID: 20927408.
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      66. Colby JB, Van Horn J, Sowell ER. Quantitative in vivo evidence for broad regional gradients in the timing of white matter maturation during adolescence. Neuroimage. 2011 Jan 1; 54(1):25-31. PMID: 20708693.
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      67. Lederman C, Joshi A, Dinov I, Van Horn J, Vese L, Toga A. TETRAHEDRAL MESH GENERATION FOR MEDICAL IMAGES WITH MULTIPLE REGIONS USING ACTIVE SURFACES. Proc IEEE Int Symp Biomed Imaging. 2010 Apr 14; 2010:436-439. PMID: 21278816.
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      68. Patel V, Dinov ID, Van Horn J, Thompson PM, Toga AW. LONI MiND: metadata in NIfTI for DWI. Neuroimage. 2010 Jun; 51(2):665-76. PMID: 20206274.
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      69. Van Horn J, Toga AW. Neuroimaging workflow design and data-mining: a frontiers in neuroinformatics special issue. Front Neuroinform. 2009; 3:31. PMID: 20339478.
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      70. Joshi SH, Marquina A, Osher SJ, Dinov I, Van Horn J, Toga AW. MRI RESOLUTION ENHANCEMENT USING TOTAL VARIATION REGULARIZATION. Proc IEEE Int Symp Biomed Imaging. 2009 Aug 7; 2009:161-164. PMID: 21113426.
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      71. Van Horn J, Toga AW. Multisite neuroimaging trials. Curr Opin Neurol. 2009 Aug; 22(4):370-8. PMID: 19506479.
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      72. Dinov ID, Van Horn J, Lozev KM, Magsipoc R, Petrosyan P, Liu Z, Mackenzie-Graham A, Eggert P, Parker DS, Toga AW. Efficient, Distributed and Interactive Neuroimaging Data Analysis Using the LONI Pipeline. Front Neuroinform. 2009; 3:22. PMID: 19649168.
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      73. Van Horn J, Toga AW. Is it time to re-prioritize neuroimaging databases and digital repositories? Neuroimage. 2009 Oct 1; 47(4):1720-34. PMID: 19371790.
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      74. Van Horn J, Grafton ST, Miller MB. Individual Variability in Brain Activity: A Nuisance or an Opportunity? Brain Imaging Behav. 2008 Dec 1; 2(4):327-334. PMID: 19777073.
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      75. Van Horn J, Bandettini PA, Cheng K, Egan GF, Stenger VA, Strother S, Toga AW. New Horizons for the Next Era of Human Brain Imaging, Cognitive, and Behavioral Research: Pacific Rim Interactivity. Brain Imaging Behav. 2008 Dec 1; 2(4):227-231. PMID: 20169011.
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      76. Van Horn J, Poldrack RA. Functional MRI at the crossroads. Int J Psychophysiol. 2009 Jul; 73(1):3-9. PMID: 19041348.
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      77. Van Horn J, Ball CA. Domain-specific data sharing in neuroscience: what do we have to learn from each other? Neuroinformatics. 2008; 6(2):117-21. PMID: 18473189.
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      78. Mackenzie-Graham AJ, Van Horn J, Woods RP, Crawford KL, Toga AW. Provenance in neuroimaging. Neuroimage. 2008 Aug 1; 42(1):178-95. PMID: 18519166.
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      79. Sowell ER, Johnson A, Kan E, Lu LH, Van Horn J, Toga AW, O'Connor MJ, Bookheimer SY. Mapping white matter integrity and neurobehavioral correlates in children with fetal alcohol spectrum disorders. J Neurosci. 2008 Feb 6; 28(6):1313-9. PMID: 18256251.
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      80. Van Horn J, Ishai A. Mapping the human brain: new insights from FMRI data sharing. Neuroinformatics. 2007; 5(3):146-53. PMID: 17917125.
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      81. Van Horn J, Grafton ST, Rockmore D, Gazzaniga MS. Sharing neuroimaging studies of human cognition. Nat Neurosci. 2004 May; 7(5):473-81. PMID: 15114361.
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