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Jeff Mc Combs, PhD

Title(s)Associate Professor
Phone+1 213 821 7941
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    Ph.D. in Economics, University of California, San Diego, 1982.

    Assistant Professor, Department of Mental Hygiene, School of Hygiene and Public Health, The Johns Hopkins University, 1980-1982.

    Senior Project Analyst, Applied Management Sciences, Silver Springs, MD, 1982-83.

    Social Science Research Analysis, Office of Research and Demonstrations, Health Care Financing Administration, 1983-1987.

    USC School of Pharmacy, Department of Pharmaceutical Economics and Policy, 1987-present.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Cho SK, McCombs J, Punwani N, Lam J. Complications and hospital costs during hematopoietic stem cell transplantation for non-Hodgkin lymphoma in the United States. Leuk Lymphoma. 2019 Mar 08; 1-7. PMID: 30848975.
      View in: PubMed
    2. Han X, McCombs J, Chu M, Dougherty JS, Fox DS. Impact of early initiation of antihypertensive medications for patients with hypertension or elevated blood pressure. J Hypertens. 2019 Jan 07. PMID: 30624365.
      View in: PubMed
    3. Han X, Fox DS, Chu M, Dougherty JS, McCombs J. Primary Prevention Using Cholesterol-Lowering Medications in Patients Meeting New Treatment Guidelines: A Retrospective Cohort Analysis. J Manag Care Spec Pharm. 2018 Nov; 24(11):1078-1085. PMID: 30362921.
      View in: PubMed
    4. Ni W, Colayco D, Hashimoto J, Komoto K, Gowda C, Wearda B, McCombs J. Reduction of healthcare costs through a transitions-of-care program. Am J Health Syst Pharm. 2018 May 15; 75(10):613-621. PMID: 29650726.
      View in: PubMed
    5. Ni W, Colayco D, Hashimoto J, Komoto K, Gowda C, Wearda B, McCombs J. Budget Impact Analysis of a Pharmacist-Provided Transition of Care Program. J Manag Care Spec Pharm. 2018 Feb; 24(2):90-96. PMID: 29384028.
      View in: PubMed
    6. Soto M, Bang SI, McCombs J, Rodgers KE. Renin Angiotensin system-modifying therapies are associated with improved pulmonary health. Clin Diabetes Endocrinol. 2017; 3:6. PMID: 28702260.
      View in: PubMed
    7. Fox DS, McGinnis JJ, Tonnu-Mihara IQ, McCombs JS. Comparative treatment effectiveness of direct acting antiviral regimens for hepatitis C: Data from the Veterans administration. J Gastroenterol Hepatol. 2017 Jun; 32(6):1136-1142. PMID: 27869323.
      View in: PubMed
    8. Jiang Y, McCombs JS, Park SH. A Retrospective Cohort Study of Acute Kidney Injury Risk Associated with Antipsychotics. CNS Drugs. 2017 Apr; 31(4):319-326. PMID: 28290080.
      View in: PubMed
    9. Ni W, Colayco D, Hashimoto J, Komoto K, Gowda C, Wearda B, McCombs J. Impact of a pharmacy-based transitional care program on hospital readmissions. Am J Manag Care. 2017 Mar; 23(3):170-176. PMID: 28385023.
      View in: PubMed
    10. Matsuda T, McCombs JS, Tonnu-Mihara I, McGinnis J, Fox DS. The Impact of Delayed Hepatitis C Viral Load Suppression on Patient Risk: Historical Evidence from the Veterans Administration. Forum Health Econ Policy. 2016 Dec 01; 19(2):333-351. PMID: 31419897.
      View in: PubMed
    11. Fox DS, McCombs JS. Optimizing HCV treatment - Moving beyond the cost conundrum. J Hepatol. 2016 07; 65(1):222-225. PMID: 26876940.
      View in: PubMed
    12. Thomas KL, Jiang Y, McCombs JS. Clozapine revisited: Impact of clozapine vs olanzapine on health care use by schizophrenia patients on Medicaid. Ann Clin Psychiatry. 2015 May; 27(2):90-9. PMID: 25696785.
      View in: PubMed
    13. McCombs JS. Essential need for research in hepatitis C. J Med Econ. 2015; 18(7):512-3. PMID: 25687753.
      View in: PubMed
    14. McCombs J, Matsuda T, Tonnu-Mihara I, Saab S, Hines P, L'italien G, Juday T, Yuan Y. The risk of long-term morbidity and mortality in patients with chronic hepatitis C: results from an analysis of data from a Department of Veterans Affairs Clinical Registry. JAMA Intern Med. 2014 Feb 01; 174(2):204-12. PMID: 24193887.
      View in: PubMed
    15. Shin J, McCombs JS, Sanchez RJ, Udall M, Deminski MC, Cheetham TC. Primary nonadherence to medications in an integrated healthcare setting. Am J Manag Care. 2012 Aug; 18(8):426-34. PMID: 22928758.
      View in: PubMed
    16. Rashid N, McCombs JS, Schwartz E. Effect of exenatide, pen insulin, and vial insulin on patient outcomes: a retrospective database analysis of persistence and first-year costs in a commercially insured population. Clin Ther. 2012 May; 34(5):1145-58. PMID: 22464691.
      View in: PubMed
    17. McCombs JS, Yuan Y, Shin J, Saab S. Economic burden associated with patients diagnosed with hepatitis C. Clin Ther. 2011 Sep; 33(9):1268-80. PMID: 21840056.
      View in: PubMed
    18. McCombs J, Zolfaghari S, Ganapathy V. Impact of drug treatment history on comparative effectiveness research in schizophrenia. Value Health. 2011 Jul-Aug; 14(5):679-86. PMID: 21839406.
      View in: PubMed
    19. Shin J, Cheetham TC, Wong L, Niu F, Kass E, Yoshinaga MA, Sorel M, McCombs JS, Sidney S. The impact of the iPLEDGE program on isotretinoin fetal exposure in an integrated health care system. J Am Acad Dermatol. 2011 Dec; 65(6):1117-25. PMID: 21565419.
      View in: PubMed
    20. Johnson KA, Chen S, Cheng IN, Lou M, Gregerson P, Blieden C, Baron M, McCombs J. The impact of clinical pharmacy services integrated into medical homes on diabetes-related clinical outcomes. Ann Pharmacother. 2010 Dec; 44(12):1877-86. PMID: 21119101.
      View in: PubMed
    21. McCombs JS, Ganapathy V, Zolfaghari S. Applying comparative effectiveness research methods in bipolar disorders. J Affect Disord. 2011 Apr; 130(1-2):145-54. PMID: 20970196.
      View in: PubMed
    22. Colayco DC, Niu F, McCombs JS, Cheetham TC. A1C and cardiovascular outcomes in type 2 diabetes: a nested case-control study. Diabetes Care. 2011 Jan; 34(1):77-83. PMID: 20937686.
      View in: PubMed
    23. Chen L, McCombs JS, Park J. Duration of antipsychotic drug therapy in real-world practice: a comparison with CATIE trial results. Value Health. 2008 May-Jun; 11(3):487-96. PMID: 18489672.
      View in: PubMed
    24. Ahn J, McCombs JS, Jung C, Croudace TJ, McDonnell D, Ascher-Svanum H, Edgell ET, Shi L. Classifying patients by antipsychotic adherence patterns using latent class analysis: characteristics of nonadherent groups in the California Medicaid (Medi-Cal) program. Value Health. 2008 Jan-Feb; 11(1):48-56. PMID: 18237360.
      View in: PubMed
    25. Chen L, McCombs JS, Park J. The impact of atypical antipsychotic medications on the use of health care by patients with schizophrenia. Value Health. 2008 Jan-Feb; 11(1):34-43. PMID: 18237358.
      View in: PubMed
    26. McCombs JS, Ahn J, Tencer T, Shi L. The impact of unrecognized bipolar disorders among patients treated for depression with antidepressants in the fee-for-services California Medicaid (Medi-Cal) program: a 6-year retrospective analysis. J Affect Disord. 2007 Jan; 97(1-3):171-9. PMID: 16860396.
      View in: PubMed
    27. Mihara IQ, McCombs JS, Williams BR. The impact of mirtazapine compared with non-TCA antidepressants on weight change in nursing facility residents. Consult Pharm. 2005 Mar; 20(3):217-23. PMID: 16548628.
      View in: PubMed
    28. Nasrallah HA, Targum SD, Tandon R, McCombs JS, Ross R. Defining and measuring clinical effectiveness in the treatment of schizophrenia. Psychiatr Serv. 2005 Mar; 56(3):273-82. PMID: 15746501.
      View in: PubMed
    29. Shi L, Thiebaud P, McCombs JS. The impact of unrecognized bipolar disorders for patients treated for depression with antidepressants in the fee-for-services California Medicaid (Medi-Cal) program. J Affect Disord. 2004 Nov 01; 82(3):373-83. PMID: 15555688.
      View in: PubMed
    30. McCombs JS, Thiebaud P, McLaughlin-Miley C, Shi J. Compliance with drug therapies for the treatment and prevention of osteoporosis. Maturitas. 2004 Jul 15; 48(3):271-87. PMID: 15207894.
      View in: PubMed
    31. McCombs J. Managing antidepressant drug therapy in an evolving marketplace. Am J Manag Care. 2004 Jul; 10(6 Suppl):S173-8. PMID: 15354674.
      View in: PubMed
    32. McCombs JS, Mulani P, Gibson PJ. Open access to innovative drugs: treatment substitutions or treatment expansion? Health Care Financ Rev. 2004; 25(3):35-53. PMID: 15229995; PMCID: PMC4194862.
    33. McCombs JS, Shi L, Croghan TW, Stimmel GL. Access to drug therapy and substitution between alternative antidepressants following an expansion of the California Medicaid formulary. Health Policy. 2003 Sep; 65(3):301-11. PMID: 12941496.
      View in: PubMed
    34. Parker JP, McCombs JS, Graddy EA. Can pharmacy data improve prediction of hospital outcomes? Comparisons with a diagnosis-based comorbidity measure. Med Care. 2003 Mar; 41(3):407-19. PMID: 12618644.
      View in: PubMed
    35. Yuan Y, Hay JW, McCombs JS. Effects of ambulatory-care pharmacist consultation on mortality and hospitalization. Am J Manag Care. 2003 Jan; 9(1):45-56. PMID: 12549814.
      View in: PubMed
    36. Oh Y, McCombs JS, Cheng RA, Johnson KA. Pharmacist time requirements for counseling in an outpatient pharmacy. Am J Health Syst Pharm. 2002 Dec 01; 59(23):2346-55. PMID: 12489376.
      View in: PubMed
    37. McCombs JS, Shi L, Stimmel GL, Croghan TW. A retrospective analysis of the revocation of prior authorization restrictions and the use of antidepressant medications for treating major depressive disorder. Clin Ther. 2002 Nov; 24(11):1939-59; discussion 1938. PMID: 12501884.
      View in: PubMed
    38. Li J, McCombs JS, Stimmel GL. Cost of treating bipolar disorder in the California Medicaid (Medi-Cal) program. J Affect Disord. 2002 Sep; 71(1-3):131-9. PMID: 12167509.
      View in: PubMed
    39. Lyu RR, McCombs JS, Johnstone BM, Muse DN. Use of conventional antipsychotics and the cost of treating schizophrenia. Health Care Financ Rev. 2001; 23(2):83-99. PMID: 12500340.
      View in: PubMed
    40. Velmahos GC, Oh Y, McCombs J, Oder D. An evidence-based cost-effectiveness model on methods of prevention of posttraumatic venous thromboembolism. J Trauma. 2000 Dec; 49(6):1059-64. PMID: 11130489.
      View in: PubMed
    41. McCombs JS, Luo M, Johnstone BM, Shi L. The use of conventional antipsychotic medications for patients with schizophrenia in a medicaid population: therapeutic and cost outcomes over 2 years. Value Health. 2000 May-Jun; 3(3):222-31. PMID: 16464186.
      View in: PubMed
    42. McCombs JS, Nichol MB, Johnstone BM, Stimmel GL, Shi J, Smith R. Antipsychotic drug use patterns and the cost of treating schizophrenia. Psychiatr Serv. 2000 Apr; 51(4):525-7. PMID: 10737831.
      View in: PubMed
    43. Streja DA, Hui RL, Streja E, McCombs JS. Selective contracting and patient outcomes: a case study of formulary restrictions for selective serotonin reuptake inhibitor antidepressants. Am J Manag Care. 1999 Sep; 5(9):1133-42. PMID: 10621079.
      View in: PubMed
    44. McCombs JS, Nichol MB, Stimmel GL. The role of SSRI antidepressants for treating depressed patients in the California Medicaid (Medi-Cal) program. Value Health. 1999 Jul-Aug; 2(4):269-80. PMID: 16674317.
      View in: PubMed
    45. Venturini F, Nichol MB, Sung JC, Bailey KL, Cody M, McCombs JS. Compliance with sulfonylureas in a health maintenance organization: a pharmacy record-based study. Ann Pharmacother. 1999 Mar; 33(3):281-8. PMID: 10200850.
      View in: PubMed
    46. Niederman MS, McCombs JS, Unger AN, Kumar A, Popovian R. Treatment cost of acute exacerbations of chronic bronchitis. Clin Ther. 1999 Mar; 21(3):576-91. PMID: 10321424.
      View in: PubMed
    47. Williams BR, Nichol MB, Lowe B, Yoon PS, McCombs JS, Margolies J. Medication use in residential care facilities for the elderly. Ann Pharmacother. 1999 Feb; 33(2):149-55. PMID: 10084408.
      View in: PubMed
    48. McCombs JS, Nichol MB, Stimmel GL, Shi J, Smith RR. Use patterns for antipsychotic medications in medicaid patients with schizophrenia. J Clin Psychiatry. 1999; 60 Suppl 19:5-11; discussion 12-3. PMID: 10507275.
      View in: PubMed
    49. Johnson KA, Parker JP, McCombs JS, Cody M. The Kaiser Permanente/USC Patient Consultation Study: patient satisfaction with pharmaceutical services. University of Southern California. Am J Health Syst Pharm. 1998 Dec 15; 55(24):2621-9. PMID: 9872701.
      View in: PubMed
    50. McCombs JS, Liu G, Shi J, Feng W, Cody M, Parker JP, Nichol MB, Hay JW, Johnson KA, Groshen SL, Nye MT. The Kaiser Permanente/USC Patient Consultation Study: change in use and cost of health care services. Am J Health Syst Pharm. 1998 Dec 01; 55(23):2485-99. PMID: 9853633.
      View in: PubMed
    51. Sung JC, Nichol MB, Venturini F, Bailey KL, McCombs JS, Cody M. Factors affecting patient compliance with antihyperlipidemic medications in an HMO population. Am J Manag Care. 1998 Oct; 4(10):1421-30. PMID: 10338735.
      View in: PubMed
    52. McCombs JS. Pharmacoeconomics: what is it and where is it going? Am J Hypertens. 1998 Aug; 11(8 Pt 2):112S-119S; discussion 135S-137S. PMID: 9717852.
      View in: PubMed
    53. Niederman MS, McCombs JS, Unger AN, Kumar A, Popovian R. The cost of treating community-acquired pneumonia. Clin Ther. 1998 Jul-Aug; 20(4):820-37. PMID: 9737840.
      View in: PubMed
    54. Gerber RA, Liu G, McCombs JS. Impact of pharmacist consultations provided to patients with diabetes on healthcare costs in a health maintenance organization. Am J Manag Care. 1998 Jul; 4(7):991-1000. PMID: 10181997.
      View in: PubMed
    55. McCombs JS, Cody M, Besinque K, Borok G, Ershoff D, Groshen S, Hay J, Johnson KA, Nichol MB, Nye MT. Measuring the impact of patient counseling in the outpatient pharmacy setting: the research design of the Kaiser Permanente/USC patient consultation study. Clin Ther. 1995 Nov-Dec; 17(6):1188-206. PMID: 8750409.
      View in: PubMed
    56. McCombs JS, Nichol MB. The use of first- and second-line outpatient antibiotics under the Saskatchewan Drug Plan. Pharmacoeconomics. 1995 Jun; 7(6):543-54. PMID: 10155339.
      View in: PubMed
    57. McCombs JS, Nichol MB, Johnson KA, Hay JW, Ebin VJ, Lawrence GD, Schneider JS. Is pharmacy's vision of the future too narrow? Am J Health Syst Pharm. 1995 Jun 01; 52(11):1208-14. PMID: 7656110.
      View in: PubMed
    58. McCombs JS, Nichol MB, Newman CM, Sclar DA. The costs of interrupting antihypertensive drug therapy in a Medicaid population. Med Care. 1994 Mar; 32(3):214-26. PMID: 8145599.
      View in: PubMed
    59. McCombs JS, Nichol MB. Pharmacy-enforced outpatient drug treatment protocols: a case study of Medi-Cal restrictions for cefaclor. Ann Pharmacother. 1993 Feb; 27(2):155-61. PMID: 8439688.
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    60. Nichol MB, McCombs JS, Johnson KA, Spacapan S, Sclar DA. The effects of consultation on over-the-counter medication purchasing decisions. Med Care. 1992 Nov; 30(11):989-1003. PMID: 1434962.
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    61. McCombs JS, Kasper JD, Riley GF. Do HMOs reduce health care costs? A multivariate analysis of two Medicare HMO demonstration projects. Health Serv Res. 1990 Oct; 25(4):593-613. PMID: 2211129.
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    62. McCombs JS, Nichol MB, Stimmel GL, Sclar DA, Beasley CM, Gross LS. The cost of antidepressant drug therapy failure: a study of antidepressant use patterns in a Medicaid population. J Clin Psychiatry. 1990 Jun; 51 Suppl:60-9; discussion 70-1. PMID: 2189876.
      View in: PubMed
    63. Kasper JD, Riley GF, McCombs JS, Stevenson MA. Beneficiary selection, use, and charges in two Medicare capitation demonstrations. Health Care Financ Rev. 1988; 10(1):37-49. PMID: 10312820.
      View in: PubMed