Hugo Rosen, MD

Title(s)Professor and Chair, Department of Medicine
Address1450 San Pablo St.
Off Campus
Los Angeles CA 90033
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    Other Positions
    Title(s)Kenneth T. Norris, Jr., Chair in Medicine


    Collapse Overview 
    Collapse Overview
    Hugo R. Rosen, MD is the Norris Chair of Medicine and Professor of Medicine, Immunology, and Molecular Microbiology.

    Rosen is a prolific physician-scientist with more than 180 original peer-reviewed manuscripts investigating the cellular and molecular underpinnings of a wide spectrum of innate and adaptive immune responses and developing novel paradigms in liver diseases. He has been the principal investigator of multiple National Institutes of Health grants (including two active RO1 grants), Center Grants, three T32 training grants and five VA Merit grants. He is an elected member of the American Society of Clinical Investigation (elected in 2008) and the American Association of Physicians. He has also received research funding from the American Society of Transplantation and American Association for the Study of Liver Diseases, having been named “Fellow” in the inaugural class of both societies. He currently serves as deputy editor of the journal Hepatology. He completed his internship and residency in internal medicine at Beth Israel Deaconess Medical Center, Harvard Medical School, followed by a fellowship in gastroenterology and transplant hepatology at UCLA. He will manage patients with acute and chronic liver disease at the Medical Center of USC and LAC+USC Medical Center.

    Collapse Research 
    Collapse Research Activities and Funding
    Mechanisms of Advanced NAFLD Disparities in Hispanics: A Multi-level Analysis
    NIH R01MD015971Jan 1, 2021 - Nov 30, 2025
    Role: Principal Investigator
    Innate Immunity, Cholesterol, and NASH Pathogenesis
    NIH R01DK117004Jan 20, 2020 - Dec 31, 2023
    Role: Principal Investigator
    Restoration of immunity and function with DAA treatment in HCV infection
    NIH R01AI120622Feb 14, 2017 - Jan 31, 2022
    Role: Principal Investigator
    Mechanisms of hepatic innate immune activation by HCV
    NIH R01AI127463Dec 15, 2016 - Nov 30, 2021
    Role: Co-Principal Investigator
    INNATE AND ADAPTIVE IMMUNITY TO HCV IN HUMAN PREGNANCY
    NIH R01HD075549Feb 7, 2014 - Jan 31, 2020
    Role: Principal Investigator
    Novel Aspects of Hepatic Innate and Adaptive Immunity to HCV Infection
    NIH I01BX002201Jan 1, 2014 - Dec 31, 2017
    Role: Principal Investigator
    Hepatitis C viral sensing by non-parenchymal liver cells (NPC)
    NIH R21AI103361May 15, 2013 - Apr 30, 2015
    Role: Principal Investigator
    HEPATITIS C VIRAL INFECTION IN HUMAN PREGNANCY
    NIH R56AI100991Sep 20, 2012 - Feb 28, 2014
    Role: Principal Investigator
    Functional attributes of CD8+ T cells in recovery of hepatitis C virus infection
    NIH I01CX000111Oct 1, 2009 - Sep 30, 2013
    Role: Principal Investigator
    Midcareer Investigator Award in Patient-Oriented Research (K24)
    NIH K24AI083742Sep 18, 2009 - Jul 31, 2014
    Role: Principal Investigator
    Innate Immune Responses During Therapy for Chronic HCV
    NIH R01DK071560Sep 30, 2005 - Jul 31, 2010
    Role: Principal Investigator
    Colorado Hepatitis C Cooperative Research Center
    NIH U19AI066328Jul 1, 2005 - Nov 30, 2016
    Role: Principal Investigator
    Immune Responses in Acute Hepatitis C Infection
    NIH R01DK060590Sep 15, 2002 - Aug 31, 2011
    Role: Principal Investigator
    Cellular Immune Mechanisms of Resistance to HCV Therapy
    NIH U01DK060342Sep 30, 2001 - Apr 30, 2007
    Role: Principal Investigator
    USC Research Center for Liver Disease
    NIH P30DK048522Mar 1, 1997 - Feb 28, 2021
    Role: Principal Investigator
    Gastrointestinal Diseases Training Grant
    NIH T32DK007038Jul 1, 1975 - Jun 30, 2021
    Role: Principal Investigator