Gordon Lithgow

Title(s)Part-Time Lecturer
SchoolSchool of Gerontology
Address3715 McClintock Ave., Suite 102
University Park Campus
Los Angeles CA 90089
Emaillithgow@usc.edu
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Genetic diversity estimates for the Caenorhabditis Intervention Testing Program screening panel. MicroPubl Biol. 2022; 2022. Teterina AA, Coleman-Hulbert AL, Banse SA, Willis JH, Perez VI, Lithgow GJ, Driscoll M, Phillips PC. PMID: 35098051; PMCID: PMC8796004.
      View in: PubMed   Mentions:
    2. Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes. Aging Cell. 2022 01; 21(1):e13488. Onken B, Sedore CA, Coleman-Hulbert AL, Hall D, Johnson E, Jones EG, Banse SA, Huynh P, Guo S, Xue J, Chen E, Harinath G, Foulger AC, Chao EA, Hope J, Bhaumik D, Plummer T, Inman D, Morshead M, Guo M, Lithgow GJ, Phillips PC, Driscoll M. PMID: 34837316; PMCID: PMC8761014.
      View in: PubMed   Mentions:
    3. Caenorhabditis Intervention Testing Program: the herbicide diuron does not robustly extend lifespan in nematodes. MicroPubl Biol. 2021; 2021. Osman HC, Sedore CA, Jackson EG, Battistoni ET, Hall D, Foulger A, Lucanic M, Guo M, Driscoll M, Phillips P, Lithgow GJ. PMID: 34585102; PMCID: PMC8461457.
      View in: PubMed   Mentions:
    4. The mitochondrial permeability transition pore activates the mitochondrial unfolded protein response and promotes aging. Elife. 2021 09 01; 10. Angeli S, Foulger A, Chamoli M, Peiris TH, Gerencser A, Shahmirzadi AA, Andersen J, Lithgow G. PMID: 34467850; PMCID: PMC8410078.
      View in: PubMed   Mentions:
    5. University of Southern California and buck institute nathan shock center: multidimensional models of aging. Geroscience. 2021 10; 43(5):2119-2127. Curran SP, Lithgow GJ, Verdin E, P C. PMID: 34269983; PMCID: PMC8599784.
      View in: PubMed   Mentions:    Fields:    
    6. Swimming exercise reduces native ⍺-synuclein protein species in a transgenic C. elegans model of Parkinson's disease. MicroPubl Biol. 2021 Jun 29; 2021. Schmidt MY, Chamoli M, Lithgow GJ, Andersen JK. PMID: 34222835; PMCID: PMC8243224.
      View in: PubMed   Mentions:
    7. Moving geroscience from the bench to clinical care and health policy. J Am Geriatr Soc. 2021 09; 69(9):2455-2463. Sierra F, Caspi A, Fortinsky RH, Haynes L, Lithgow GJ, Moffitt TE, Olshansky SJ, Perry D, Verdin E, Kuchel GA. PMID: 34145908.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Career Retrospective: Tom Johnson-Genetics, Genomics, Stress, Stochastic Variation, and Aging. J Gerontol A Biol Sci Med Sci. 2021 06 14; 76(7):e85-e91. Mendenhall AR, Lithgow GJ, Kim S, Friedman D, Newell-Stamper BL, Johnson TE. PMID: 33609361; PMCID: PMC8600024.
      View in: PubMed   Mentions:
    9. Trimethylamine modulates dauer formation, neurodegeneration, and lifespan through tyra-3/daf-11 signaling in Caenorhabditis elegans. Aging Cell. 2021 05; 20(5):e13351. Khanna A, Sellegounder D, Kumar J, Chamoli M, Vargas M, Chinta SJ, Rane A, Nelson C, Peiris TH, Brem R, Andersen J, Lithgow G, Kapahi P. PMID: 33819374; PMCID: PMC8135002.
      View in: PubMed   Mentions:
    10. Longitudinal Functional Study of Murine Aging: A Resource for Future Study Designs. JBMR Plus. 2021 Mar; 5(3):e10466. Evans DS, O'Leary MN, Murphy R, Schmidt M, Koenig K, Presley M, Garrett B, Kim HN, Han L, Academia EC, Laye MJ, Edgar D, Zambataro CA, Barhydt T, Dewey CM, Mayfield J, Wilson J, Alavez S, Lucanic M, Kennedy BK, Almeida M, Andersen JK, Kapahi P, Lithgow GJ, Melov S. PMID: 33778327; PMCID: PMC7990142.
      View in: PubMed   Mentions:
    11. A simplified design for the C. elegans lifespan machine. J Biol Methods. 2020; 7(4):e137. Abbott M, Banse SA, Melentijevic I, Jarrett CM, Ange JS, Sedore CA, Falkowski R, Blue BW, Coleman-Hulbert AL, Johnson E, Guo M, Lithgow GJ, Phillips PC, Driscoll M. PMID: 33204740; PMCID: PMC7666331.
      View in: PubMed   Mentions:
    12. Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction. Nat Commun. 2020 09 25; 11(1):4865. Chamoli M, Goyala A, Tabrez SS, Siddiqui AA, Singh A, Antebi A, Lithgow GJ, Watts JL, Mukhopadhyay A. PMID: 32978396; PMCID: PMC7519657.
      View in: PubMed   Mentions:
    13. Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice. Cell Metab. 2020 09 01; 32(3):447-456.e6. Asadi Shahmirzadi A, Edgar D, Liao CY, Hsu YM, Lucanic M, Asadi Shahmirzadi A, Wiley CD, Gan G, Kim DE, Kasler HG, Kuehnemann C, Kaplowitz B, Bhaumik D, Riley RR, Kennedy BK, Lithgow GJ. PMID: 32877690; PMCID: PMC8508957.
      View in: PubMed   Mentions:
    14. Quantification of Insoluble Protein Aggregation in Caenorhabditis elegans during Aging with a Novel Data-Independent Acquisition Workflow. J Vis Exp. 2020 08 07; (162). Xie X, Chamoli M, Bhaumik D, Sivapatham R, Angeli S, Andersen JK, Lithgow GJ, Schilling B. PMID: 32831297; PMCID: PMC7519758.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    15. Caenorhabditis Intervention Testing Program: the farnesoid X receptor agonist obeticholic acid does not robustly extend lifespan in nematodes. MicroPubl Biol. 2020 May 27; 2020. Morshead ML, Sedore CA, Jones EG, Hall D, Plummer WT, Garrett T, Lucanic M, Guo M, Driscoll M, Phillips PC, Lithgow G. PMID: 32550518; PMCID: PMC7253371.
      View in: PubMed   Mentions:
    16. Kavain suppresses human Aβ-induced paralysis in C. elegans. MicroPubl Biol. 2020 May 21; 2020. Chamoli M, Chinta SJ, Andersen JK, Lithgow GJ. PMID: 32550490; PMCID: PMC7252289.
      View in: PubMed   Mentions:
    17. Dysregulated iron metabolism in C. elegans catp-6/ATP13A2 mutant impairs mitochondrial function. Neurobiol Dis. 2020 06; 139:104786. Anand N, Holcom A, Broussalian M, Schmidt M, Chinta SJ, Lithgow GJ, Andersen JK, Chamoli M. PMID: 32032734; PMCID: PMC7150649.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    18. Caenorhabditis Intervention Testing Program: the creatine analog β-guanidinopropionic acid does not extend lifespan in nematodes. MicroPubl Biol. 2020; 2020. Coleman-Hulbert AL, Johnson E, Sedore CA, Banse SA, Guo M, Driscoll M, Lithgow GJ, Phillips PC. PMID: 31998863; PMCID: PMC6988715.
      View in: PubMed   Mentions: 4  
    19. Automated lifespan determination across Caenorhabditis strains and species reveals assay-specific effects of chemical interventions. Geroscience. 2019 12; 41(6):945-960. Banse SA, Lucanic M, Sedore CA, Coleman-Hulbert AL, Plummer WT, Chen E, Kish JL, Hall D, Onken B, Presley MP, Jones EG, Blue BW, Garrett T, Abbott M, Xue J, Guo S, Johnson E, Foulger AC, Chamoli M, Falkowski R, Melentijevic I, Harinath G, Huynh P, Patel S, Edgar D, Jarrett CM, Guo M, Kapahi P, Lithgow GJ, Driscoll M, Phillips PC. PMID: 31820364; PMCID: PMC6925072.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    20. From discoveries in ageing research to therapeutics for healthy ageing. Nature. 2019 07; 571(7764):183-192. Campisi J, Kapahi P, Lithgow GJ, Melov S, Newman JC, Verdin E. PMID: 31292558; PMCID: PMC7205183.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCells
    21. Caenorhabditis Intervention Testing Program: the tyrosine kinase inhibitor imatinib mesylate does not extend lifespan in nematodes. MicroPubl Biol. 2019; 2019. Coleman-Hulbert AL, Johnson E, Sedore CA, Banse SA, Guo M, Driscoll M, Lithgow GJ, Phillips PC. PMID: 32010883; PMCID: PMC6993932.
      View in: PubMed   Mentions: 5  
    22. Drugs that target aging: how do we discover them? Expert Opin Drug Discov. 2019 06; 14(6):541-548. Myers A, Lithgow GJ. PMID: 30973028; PMCID: PMC6497572.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    23. Acarbose improves health and lifespan in aging HET3 mice. Aging Cell. 2019 04; 18(2):e12898. Harrison DE, Strong R, Alavez S, Astle CM, DiGiovanni J, Fernandez E, Flurkey K, Garratt M, Gelfond JAL, Javors MA, Levi M, Lithgow GJ, Macchiarini F, Nelson JF, Sukoff Rizzo SJ, Slaga TJ, Stearns T, Wilkinson JE, Miller RA. PMID: 30688027; PMCID: PMC6413665.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    24. Natural Genetic Variation in Yeast Reveals That NEDD4 Is a Conserved Modifier of Mutant Polyglutamine Aggregation. G3 (Bethesda). 2018 11 06; 8(11):3421-3431. Peters TW, Nelson CS, Gerencser AA, Dumas KJ, Tavshanjian B, Chang KC, Lithgow GJ, Hughes RE. PMID: 30194090; PMCID: PMC6222566.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    25. A Simple Method for High Throughput Chemical Screening in Caenorhabditis Elegans. J Vis Exp. 2018 03 20; (133). Lucanic M, Garrett T, Gill MS, Lithgow GJ. PMID: 29630057; PMCID: PMC5933220.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    26. A long journey to reproducible results. Nature. 2017 08 22; 548(7668):387-388. Lithgow GJ, Driscoll M, Phillips P. PMID: 28836615; PMCID: PMC5762131.
      View in: PubMed   Mentions: 33     Fields:    
    27. Anti-Inflammatory and Neuroprotective Role of Natural Product Securinine in Activated Glial Cells: Implications for Parkinson's Disease. Mediators Inflamm. 2017; 2017:8302636. Leonoudakis D, Rane A, Angeli S, Lithgow GJ, Andersen JK, Chinta SJ. PMID: 28473732; PMCID: PMC5394397.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    28. Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects. Nat Commun. 2017 02 21; 8:14256. Lucanic M, Plummer WT, Chen E, Harke J, Foulger AC, Onken B, Coleman-Hulbert AL, Dumas KJ, Guo S, Johnson E, Bhaumik D, Xue J, Crist AB, Presley MP, Harinath G, Sedore CA, Chamoli M, Kamat S, Chen MK, Angeli S, Chang C, Willis JH, Edgar D, Royal MA, Chao EA, Patel S, Garrett T, Ibanez-Ventoso C, Hope J, Kish JL, Guo M, Lithgow GJ, Driscoll M, Phillips PC. PMID: 28220799; PMCID: PMC5321775.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    29. Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1. Cell Rep. 2016 10 25; 17(5):1227-1237. Mark KA, Dumas KJ, Bhaumik D, Schilling B, Davis S, Oron TR, Sorensen DJ, Lucanic M, Brem RB, Melov S, Ramanathan A, Gibson BW, Lithgow GJ. PMID: 27783938; PMCID: PMC5689451.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    30. A Caenorhabditis elegans Model Elucidates a Conserved Role for TRPA1-Nrf Signaling in Reactive α-Dicarbonyl Detoxification. Curr Biol. 2016 11 21; 26(22):3014-3025. Chaudhuri J, Bose N, Gong J, Hall D, Rifkind A, Bhaumik D, Peiris TH, Chamoli M, Le CH, Liu J, Lithgow GJ, Ramanathan A, Xu XZS, Kapahi P. PMID: 27773573; PMCID: PMC5135008.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    31. Chemical activation of a food deprivation signal extends lifespan. Aging Cell. 2016 10; 15(5):832-41. Lucanic M, Garrett T, Yu I, Calahorro F, Asadi Shahmirzadi A, Miller A, Gill MS, Hughes RE, Holden-Dye L, Lithgow GJ. PMID: 27220516; PMCID: PMC5013014.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    32. Zinc Levels Modulate Lifespan through Multiple Longevity Pathways in Caenorhabditis elegans. PLoS One. 2016; 11(4):e0153513. Kumar J, Barhydt T, Awasthi A, Lithgow GJ, Killilea DW, Kapahi P. PMID: 27078872; PMCID: PMC4831763.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    33. Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. Aging Cell. 2016 Apr; 15(2):196-207. Martins R, Lithgow GJ, Link W. PMID: 26643314; PMCID: PMC4783344.
      View in: PubMed   Mentions: 181     Fields:    Translation:HumansAnimalsCells
    34. Mitochondrial Quality Control via the PGC1α-TFEB Signaling Pathway Is Compromised by Parkin Q311X Mutation But Independently Restored by Rapamycin. J Neurosci. 2015 Sep 16; 35(37):12833-44. Siddiqui A, Bhaumik D, Chinta SJ, Rane A, Rajagopalan S, Lieu CA, Lithgow GJ, Andersen JK. PMID: 26377470; PMCID: PMC4571606.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    35. Geroscience: linking aging to chronic disease. Cell. 2014 Nov 06; 159(4):709-13. Kennedy BK, Berger SL, Brunet A, Campisi J, Cuervo AM, Epel ES, Franceschi C, Lithgow GJ, Morimoto RI, Pessin JE, Rando TA, Richardson A, Schadt EE, Wyss-Coray T, Sierra F. PMID: 25417146; PMCID: PMC4852871.
      View in: PubMed   Mentions: 506     Fields:    Translation:HumansAnimals
    36. Iron promotes protein insolubility and aging in C. elegans. Aging (Albany NY). 2014 Nov; 6(11):975-91. Klang IM, Schilling B, Sorensen DJ, Sahu AK, Kapahi P, Andersen JK, Swoboda P, Killilea DW, Gibson BW, Lithgow GJ. PMID: 25554795; PMCID: PMC4276790.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    37. Manganese disturbs metal and protein homeostasis in Caenorhabditis elegans. Metallomics. 2014 Oct; 6(10):1816-23. Angeli S, Barhydt T, Jacobs R, Killilea DW, Lithgow GJ, Andersen JK. PMID: 25057947; PMCID: PMC4309368.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    38. Stress biology and aging mechanisms: toward understanding the deep connection between adaptation to stress and longevity. J Gerontol A Biol Sci Med Sci. 2014 Jun; 69 Suppl 1:S10-6. Epel ES, Lithgow GJ. PMID: 24833580; PMCID: PMC4022128.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    39. Loss of NDG-4 extends lifespan and stress resistance in Caenorhabditis elegans. Aging Cell. 2014 Feb; 13(1):156-64. Brejning J, Nørgaard S, Schøler L, Morthorst TH, Jakobsen H, Lithgow GJ, Jensen LT, Olsen A. PMID: 24286221; PMCID: PMC3919970.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    40. A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY). 2013 Oct; 5(10):759-69. Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK. PMID: 24123581; PMCID: PMC3838778.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    41. Age-related micro-RNA abundance in individual C. elegans. Aging (Albany NY). 2013 Jun; 5(6):394-411. Lucanic M, Graham J, Scott G, Bhaumik D, Benz CC, Hubbard A, Lithgow GJ, Melov S. PMID: 23793570; PMCID: PMC3824409.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    42. Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev. 2013 Mar; 134(3-4):69-78. Frankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM. PMID: 23313473.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    43. Curcumin and neurodegenerative diseases. Biofactors. 2013 Jan-Feb; 39(1):122-32. Monroy A, Lithgow GJ, Alavez S. PMID: 23303664; PMCID: PMC3578106.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    44. Tor1 regulates protein solubility in Saccharomyces cerevisiae. Mol Biol Cell. 2012 Dec; 23(24):4679-88. Peters TW, Rardin MJ, Czerwieniec G, Evani US, Reis-Rodrigues P, Lithgow GJ, Mooney SD, Gibson BW, Hughes RE. PMID: 23097491; PMCID: PMC3521677.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    45. Translating longevity research into healthspan. Longev Healthspan. 2012; 1:1. Lithgow GJ, Lord JM, Kirkland JL. PMID: 24764507; PMCID: PMC3886258.
      View in: PubMed   Mentions:
    46. Pharmacological lifespan extension of invertebrates. Ageing Res Rev. 2013 Jan; 12(1):445-58. Lucanic M, Lithgow GJ, Alavez S. PMID: 22771382; PMCID: PMC3552093.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    47. Anti-inflammatory role of the isoflavone diadzein in lipopolysaccharide-stimulated microglia: implications for Parkinson's disease. Neurotox Res. 2013 Feb; 23(2):145-53. Chinta SJ, Ganesan A, Reis-Rodrigues P, Lithgow GJ, Andersen JK. PMID: 22573480; PMCID: PMC3597389.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    48. Aluminium exposure disrupts elemental homeostasis in Caenorhabditis elegans. Metallomics. 2012 May; 4(5):512-22. Page KE, White KN, McCrohan CR, Killilea DW, Lithgow GJ. PMID: 22534883; PMCID: PMC3589999.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsPHPublic Health
    49. Pharmacological maintenance of protein homeostasis could postpone age-related disease. Aging Cell. 2012 Apr; 11(2):187-91. Alavez S, Lithgow GJ. PMID: 22226190; PMCID: PMC3306462.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    50. Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan. Aging Cell. 2012 Feb; 11(1):120-7. Reis-Rodrigues P, Czerwieniec G, Peters TW, Evani US, Alavez S, Gaman EA, Vantipalli M, Mooney SD, Gibson BW, Lithgow GJ, Hughes RE. PMID: 22103665; PMCID: PMC3437485.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimals
    51. Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans. Cell Metab. 2011 Jul 06; 14(1):55-66. Rogers AN, Chen D, McColl G, Czerwieniec G, Felkey K, Gibson BW, Hubbard A, Melov S, Lithgow GJ, Kapahi P. PMID: 21723504; PMCID: PMC3220185.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    52. N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans. Nature. 2011 May 12; 473(7346):226-9. Lucanic M, Held JM, Vantipalli MC, Klang IM, Graham JB, Gibson BW, Lithgow GJ, Gill MS. PMID: 21562563; PMCID: PMC3093655.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    53. A new look at old compounds. Aging (Albany NY). 2011 Apr; 3(4):338-9. Alavez S, Lithgow GJ. PMID: 21512207; PMCID: PMC3117445.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    54. Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan. Nature. 2011 Apr 14; 472(7342):226-9. Alavez S, Vantipalli MC, Zucker DJ, Klang IM, Lithgow GJ. PMID: 21451522; PMCID: PMC3610427.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansAnimalsCells
    55. Insulin-like signaling determines survival during stress via posttranscriptional mechanisms in C. elegans. Cell Metab. 2010 Sep 08; 12(3):260-72. McColl G, Rogers AN, Alavez S, Hubbard AE, Melov S, Link CD, Bush AI, Kapahi P, Lithgow GJ. PMID: 20816092; PMCID: PMC2945254.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    56. MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8. Aging (Albany NY). 2009 Apr; 1(4):402-11. Bhaumik D, Scott GK, Schokrpur S, Patil CK, Orjalo AV, Rodier F, Lithgow GJ, Campisi J. PMID: 20148189; PMCID: PMC2818025.
      View in: PubMed   Mentions: 180     Fields:    Translation:HumansCells
    57. Compounds that confer thermal stress resistance and extended lifespan. Exp Gerontol. 2008 Oct; 43(10):882-91. Benedetti MG, Foster AL, Vantipalli MC, White MP, Sampayo JN, Gill MS, Olsen A, Lithgow GJ. PMID: 18755260; PMCID: PMC2603168.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    58. The Caenorhabditis elegans K10C2.4 gene encodes a member of the fumarylacetoacetate hydrolase family: a Caenorhabditis elegans model of type I tyrosinemia. J Biol Chem. 2008 Apr 04; 283(14):9127-35. Fisher AL, Page KE, Lithgow GJ, Nash L. PMID: 18227072; PMCID: PMC2431024.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    59. Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans. J Biol Chem. 2008 Jan 04; 283(1):350-357. McColl G, Killilea DW, Hubbard AE, Vantipalli MC, Melov S, Lithgow GJ. PMID: 17959600; PMCID: PMC2739662.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    60. Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. Aging Cell. 2007 Feb; 6(1):111-9. Pan KZ, Palter JE, Rogers AN, Olsen A, Chen D, Lithgow GJ, Kapahi P. PMID: 17266680; PMCID: PMC2745345.
      View in: PubMed   Mentions: 209     Fields:    Translation:AnimalsCells
    61. Why aging isn't regulated: a lamentation on the use of language in aging literature. Exp Gerontol. 2006 Oct; 41(10):890-3. Lithgow GJ. PMID: 16959457.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    62. DAF-12-dependent rescue of dauer formation in Caenorhabditis elegans by (25S)-cholestenoic acid. Aging Cell. 2006 Aug; 5(4):283-91. Held JM, White MP, Fisher AL, Gibson BW, Lithgow GJ, Gill MS. PMID: 16913876.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    63. Lifespan extension of Caenorhabditis elegans following repeated mild hormetic heat treatments. Biogerontology. 2006 Aug; 7(4):221-30. Olsen A, Vantipalli MC, Lithgow GJ. PMID: 16826446.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    64. Checkpoint proteins control survival of the postmitotic cells in Caenorhabditis elegans. Science. 2006 Jun 02; 312(5778):1381-5. Olsen A, Vantipalli MC, Lithgow GJ. PMID: 16741121; PMCID: PMC2568993.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    65. Using Caenorhabditis elegans as a model for aging and age-related diseases. Ann N Y Acad Sci. 2006 May; 1067:120-8. Olsen A, Vantipalli MC, Lithgow GJ. PMID: 16803977.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    66. The nuclear hormone receptor DAF-12 has opposing effects on Caenorhabditis elegans lifespan and regulates genes repressed in multiple long-lived worms. Aging Cell. 2006 Apr; 5(2):127-38. Fisher AL, Lithgow GJ. PMID: 16626392.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    67. Pharmacological intervention in invertebrate aging. Age (Dordr). 2005 Sep; 27(3):213-23. Lithgow GJ, Gill MS, Olsen A, Sampayo JN. PMID: 23598654; PMCID: PMC3458493.
      View in: PubMed   Mentions: 9     Fields:    
    68. Manganous ion supplementation accelerates wild type development, enhances stress resistance, and rescues the life span of a short-lived Caenorhabditis elegans mutant. Free Radic Biol Med. 2006 Apr 01; 40(7):1185-93. Lin YT, Hoang H, Hsieh SI, Rangel N, Foster AL, Sampayo JN, Lithgow GJ, Srinivasan C. PMID: 16545686.
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    69. Science fact and the SENS agenda. What can we reasonably expect from ageing research? EMBO Rep. 2005 Nov; 6(11):1006-8. Warner H, Anderson J, Austad S, Bergamini E, Bredesen D, Butler R, Carnes BA, Clark BF, Cristofalo V, Faulkner J, Guarente L, Harrison DE, Kirkwood T, Lithgow G, Martin G, Masoro E, Melov S, Miller RA, Olshansky SJ, Partridge L, Pereira-Smith O, Perls T, Richardson A, Smith J, von Zglinicki T, Wang E, Wei JY, Williams TF. PMID: 16264422; PMCID: PMC1371037.
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    70. The C. elegans ortholog of mammalian Ku70, interacts with insulin-like signaling to modulate stress resistance and life span. FASEB J. 2005 Oct; 19(12):1716-8. McColl G, Vantipalli MC, Lithgow GJ. PMID: 16099946; PMCID: PMC1400606.
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    71. Fitness cost of extended lifespan in Caenorhabditis elegans. Proc Biol Sci. 2004 Dec 07; 271(1556):2523-6. Jenkins NL, McColl G, Lithgow GJ. PMID: 15590605; PMCID: PMC1440519.
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    72. Lipophilic regulator of a developmental switch in Caenorhabditis elegans. Aging Cell. 2004 Dec; 3(6):413-21. Gill MS, Held JM, Fisher AL, Gibson BW, Lithgow GJ. PMID: 15569358.
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    73. S.W.A.T.--SOD weapons and tactics. Sci Aging Knowledge Environ. 2004 Jun 23; 2004(25):pe27. Sampayo JN, Lithgow GJ. PMID: 15215539.
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    74. Oxidative stress in Caenorhabditis elegans: protective effects of superoxide dismutase/catalase mimetics. Aging Cell. 2003 12; 2(6):319-26. Sampayo JN, Olsen A, Lithgow GJ. PMID: 14677634.
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    75. Oxidative stress and aging--the use of superoxide dismutase/catalase mimetics to extend lifespan. Biochem Soc Trans. 2003 Dec; 31(Pt 6):1305-7. Sampayo JN, Gill MS, Lithgow GJ. PMID: 14641049.
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    76. An automated high-throughput assay for survival of the nematode Caenorhabditis elegans. Free Radic Biol Med. 2003 Sep 15; 35(6):558-65. Gill MS, Olsen A, Sampayo JN, Lithgow GJ. PMID: 12957648.
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    77. M142.2 (cut-6), a novel Caenorhabditis elegans matrix gene important for dauer body shape. Dev Biol. 2003 Aug 15; 260(2):339-51. Muriel JM, Brannan M, Taylor K, Johnstone IL, Lithgow GJ, Tuckwell D. PMID: 12921736.
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    78. Does anti-aging equal anti-microbial? Sci Aging Knowledge Environ. 2003 Jun 25; 2003(25):PE16. Lithgow GJ. PMID: 12844540.
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    79. Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin-like signals. Aging Cell. 2003 04; 2(2):131-9. Walker GA, Lithgow GJ. PMID: 12882326.
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    80. Physiology: Cost-free longevity in mice? Nature. 2003 Jan 09; 421(6919):125-6. Lithgow GJ, Gill MS. PMID: 12520289.
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    81. Identification of a novel cis-regulatory element involved in the heat shock response in Caenorhabditis elegans using microarray gene expression and computational methods. Genome Res. 2002 May; 12(5):701-12. GuhaThakurta D, Palomar L, Stormo GD, Tedesco P, Johnson TE, Walker DW, Lithgow G, Kim S, Link CD. PMID: 11997337; PMCID: PMC186591.
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    82. Stress resistance as a determinate of C. elegans lifespan. Mech Ageing Dev. 2002 Apr; 123(7):765-71. Lithgow GJ, Walker GA. PMID: 11869734.
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    83. Heat shock protein accumulation is upregulated in a long-lived mutant of Caenorhabditis elegans. J Gerontol A Biol Sci Med Sci. 2001 Jul; 56(7):B281-7. Walker GA, White TM, McColl G, Jenkins NL, Babich S, Candido EP, Johnson TE, Lithgow GJ. PMID: 11445592.
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    84. Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans. FASEB J. 2001 Mar; 15(3):627-34. Barsyte D, Lovejoy DA, Lithgow GJ. PMID: 11259381.
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    85. Extension of life-span with superoxide dismutase/catalase mimetics. Science. 2000 Sep 01; 289(5484):1567-9. Melov S, Ravenscroft J, Malik S, Gill MS, Walker DW, Clayton PE, Wallace DC, Malfroy B, Doctrow SR, Lithgow GJ. PMID: 10968795.
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    86. Testing evolutionary theories of aging. Ann N Y Acad Sci. 2000 Jun; 908:319-20. McColl G, Jenkins NL, Walker DW, Lithgow GJ. PMID: 10911975.
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    87. Using stress resistance to isolate novel longevity mutations in Caenorhabditis elegans. Ann N Y Acad Sci. 2000 Jun; 908:324-6. Sampayo JN, Jenkins NL, Lithgow GJ. PMID: 10911977.
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    88. Evolution of lifespan in C. elegans. Nature. 2000 May 18; 405(6784):296-7. Walker DW, McColl G, Jenkins NL, Harris J, Lithgow GJ. PMID: 10830948.
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    89. The real Dorian Gray mouse. Bioessays. 2000 May; 22(5):410-3. Lithgow GJ, Andersen JK. PMID: 10797480.
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    90. Stress response and aging in Caenorhabditis elegans. Results Probl Cell Differ. 2000; 29:131-48. Lithgow GJ. PMID: 10838698.
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    91. P13-kinase inhibition induces dauer formation, thermotolerance and longevity in C. elegans. Neurobiol Aging. 1999 Sep-Oct; 20(5):513-9. Babar P, Adamson C, Walker GA, Walker DW, Lithgow GJ. PMID: 10638524.
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    92. A relationship between thermotolerance and longevity in Caenorhabditis elegans. J Investig Dermatol Symp Proc. 1998 Aug; 3(1):6-10. Walker GA, Walker DW, Lithgow GJ. PMID: 9732049.
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    93. Genes that determine both thermotolerance and rate of aging in Caenorhabditis elegans. Ann N Y Acad Sci. 1998 Jun 30; 851:444-9. Walker GA, Walker DW, Lithgow GJ. PMID: 9668638.
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    94. Hypothesis: interventions that increase the response to stress offer the potential for effective life prolongation and increased health. J Gerontol A Biol Sci Med Sci. 1996 Nov; 51(6):B392-5. Johnson TE, Lithgow GJ, Murakami S. PMID: 8914487.
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    95. Invertebrate gerontology: the age mutations of Caenorhabditis elegans. Bioessays. 1996 Oct; 18(10):809-15. Lithgow GJ. PMID: 8885718.
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    96. Mechanisms and evolution of aging. Science. 1996 Jul 05; 273(5271):80. Lithgow GJ, Kirkwood TB. PMID: 8658201.
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    97. Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc Natl Acad Sci U S A. 1995 Aug 01; 92(16):7540-4. Lithgow GJ, White TM, Melov S, Johnson TE. PMID: 7638227; PMCID: PMC41375.
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    98. Increased frequency of deletions in the mitochondrial genome with age of Caenorhabditis elegans. Nucleic Acids Res. 1995 Apr 25; 23(8):1419-25. Melov S, Lithgow GJ, Fischer DR, Tedesco PM, Johnson TE. PMID: 7753635; PMCID: PMC306871.
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    99. Rates of mortality in populations of Caenorhabditis elegans. Science. 1994 Nov 04; 266(5186):826; author reply 828. Vaupel JW, Johnson TE, Lithgow GJ. PMID: 7973641.
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    100. Thermotolerance of a long-lived mutant of Caenorhabditis elegans. J Gerontol. 1994 Nov; 49(6):B270-6. Lithgow GJ, White TM, Hinerfeld DA, Johnson TE. PMID: 7963273.
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    101. Mortality rates in a genetically heterogeneous population of Caenorhabditis elegans. Science. 1994 Feb 04; 263(5147):668-71. Brooks A, Lithgow GJ, Johnson TE. PMID: 8303273.
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    102. Comparing mutants, selective breeding, and transgenics in the dissection of aging processes of Caenorhabditis elegans. Genetica. 1993; 91(1-3):65-77. Johnson TE, Tedesco PM, Lithgow GJ. PMID: 8125279.
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    103. The search for the genetic basis of aging: the identification of gerontogenes in the nematode Caenorhabditis elegans. J Am Geriatr Soc. 1992 Sep; 40(9):936-45. Johnson TE, Lithgow GJ. PMID: 1355097.
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