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Gopalan Sethuraman

Title(s)Associate Professor of Research Neurology
AddressATR 9860 Mesa Rim Road
Off Campus
San Diego CA 92121
Phone+1 858 964 0794
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A novel cognitive disease progression model for clinical trials in autosomal-dominant Alzheimer's disease. Stat Med. 2018 09 20; 37(21):3047-3055. Wang G, Berry S, Xiong C, Hassenstab J, Quintana M, McDade EM, Delmar P, Vestrucci M, Sethuraman G, Bateman RJ. PMID: 29761523.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    2. Representativeness of European clinical trial populations in mild Alzheimer's disease dementia: a comparison of 18-month outcomes with real-world data from the GERAS observational study. Alzheimers Res Ther. 2018 04 03; 10(1):36. Reed C, Belger M, Dell'Agnello G, Kahle-Wrobleski K, Sethuraman G, Hake A, Raskin J, Henley D. PMID: 29615123.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Phase 3 solanezumab trials: Secondary outcomes in mild Alzheimer's disease patients. Alzheimers Dement. 2016 Feb; 12(2):110-120. Siemers ER, Sundell KL, Carlson C, Case M, Sethuraman G, Liu-Seifert H, Dowsett SA, Pontecorvo MJ, Dean RA, Demattos R. PMID: 26238576.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCTClinical Trials
    4. Delayed-start analysis: Mild Alzheimer's disease patients in solanezumab trials, 3.5 years. Alzheimers Dement (N Y). 2015 Sep; 1(2):111-121. Liu-Seifert H, Siemers E, Holdridge KC, Andersen SW, Lipkovich I, Carlson C, Sethuraman G, Hoog S, Hayduk R, Doody R, Aisen P. PMID: 29854931.
      View in: PubMed   Mentions:
    5. Peripheral and central effects of ?-secretase inhibition by semagacestat in Alzheimer's disease. Alzheimers Res Ther. 2015; 7(1):36. Doody RS, Raman R, Sperling RA, Seimers E, Sethuraman G, Mohs R, Farlow M, Iwatsubo T, Vellas B, Sun X, Ernstrom K, Thomas RG, Aisen PS. PMID: 26064192.
      View in: PubMed   Mentions: 8     Fields:    
    6. Safety profile of semagacestat, a gamma-secretase inhibitor: IDENTITY trial findings. Curr Med Res Opin. 2014 Oct; 30(10):2021-32. Henley DB, Sundell KL, Sethuraman G, Dowsett SA, May PC. PMID: 24983746.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    7. Adverse events and dropouts in Alzheimer's disease studies: what can we learn? Alzheimers Dement. 2015 Jan; 11(1):24-31. Henley DB, Sundell KL, Sethuraman G, Schneider LS. PMID: 24613705.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. Assessment of type I error rate associated with dose-group switching in a longitudinal Alzheimer trial. J Biopharm Stat. 2014; 24(3):660-84. Habteab Ghebretinsae A, Molenberghs G, Dmitrienko A, Offen W, Sethuraman G. PMID: 24697817.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. A phase 3 trial of semagacestat for treatment of Alzheimer's disease. N Engl J Med. 2013 Jul 25; 369(4):341-50. Doody RS, Raman R, Farlow M, Iwatsubo T, Vellas B, Joffe S, Kieburtz K, He F, Sun X, Thomas RG, Aisen PS, Siemers E, Sethuraman G, Mohs R. PMID: 23883379.
      View in: PubMed   Mentions: 262     Fields:    Translation:HumansCTClinical Trials
    10. Safety and biomarker effects of solanezumab in patients with Alzheimer's disease. Alzheimers Dement. 2012 Jul; 8(4):261-71. Farlow M, Arnold SE, van Dyck CH, Aisen PS, Snider BJ, Porsteinsson AP, Friedrich S, Dean RA, Gonzales C, Sethuraman G, DeMattos RB, Mohs R, Paul SM, Siemers ER. PMID: 22672770.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCTClinical Trials
    11. Enriching amnestic mild cognitive impairment populations for clinical trials: optimal combination of biomarkers to predict conversion to dementia. J Alzheimers Dis. 2012; 32(2):373-85. Yu P, Dean RA, Hall SD, Qi Y, Sethuraman G, Willis BA, Siemers ER, Martenyi F, Tauscher JT, Schwarz AJ. PMID: 22796873.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    12. Safety profile of Alzheimer's disease populations in Alzheimer's Disease Neuroimaging Initiative and other 18-month studies. Alzheimers Dement. 2012 Sep; 8(5):407-16. Henley DB, Sundell KL, Sethuraman G, Siemers ER. PMID: 22138370.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    13. Validation of ELISA methods for quantification of total tau and phosporylated-tau181 in human cerebrospinal fluid with measurement in specimens from two Alzheimer's disease studies. J Alzheimers Dis. 2011; 26(3):531-41. Lachno DR, Romeo MJ, Siemers ER, Vanderstichele H, Coart E, Konrad RJ, Zajac JJ, Talbot JA, Jensen HF, Sethuraman G, Demattos RB, May PC, Dean RA. PMID: 21694458.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    14. Olanzapine long-acting injection: a 24-week, randomized, double-blind trial of maintenance treatment in patients with schizophrenia. Am J Psychiatry. 2010 Feb; 167(2):181-9. Kane JM, Detke HC, Naber D, Sethuraman G, Lin DY, Bergstrom RF, McDonnell D. PMID: 20008947.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    15. In search of moderators and mediators of hyperglycemia with atypical antipsychotic treatment. J Psychiatr Res. 2009 Jul; 43(11):997-1002. Reaven GM, Lieberman JA, Sethuraman G, Kraemer H, Davis JM, Blasey C, Tsuang MT, Schatzberg AF. PMID: 19268968.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    16. Characteristics of two alternative schizophrenia remission definitions: relationship to clinical and quality of life outcomes. Schizophr Res. 2006 Sep; 86(1-3):300-8. Dunayevich E, Sethuraman G, Enerson M, Taylor CC, Lin D. PMID: 16860974.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    17. Response to Kujawa et al. letter-to-the-editor. Schizophr Res. 2006 May; 84(1):172-3. Sethuraman G, Taylor CC, Enerson M, Dunayevich E. PMID: 16563702.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Rapamycin causes regression of astrocytomas in tuberous sclerosis complex. Ann Neurol. 2006 Mar; 59(3):490-8. Franz DN, Leonard J, Tudor C, Chuck G, Care M, Sethuraman G, Dinopoulos A, Thomas G, Crone KR. PMID: 16453317.
      View in: PubMed   Mentions: 189     Fields:    Translation:Humans
    19. Is quality of life among minimally symptomatic patients with schizophrenia better following withdrawal or continuation of antipsychotic treatment? J Clin Psychopharmacol. 2006 Feb; 26(1):40-4. Beasley CM, Sutton VK, Taylor CC, Sethuraman G, Dossenbach M, Naber D. PMID: 16415704.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    20. Impulsive aggression with irritability and responsive to divalproex: a pediatric bipolar spectrum disorder phenotype? J Affect Disord. 2005 Nov; 88(3):279-85. Barzman DH, McConville BJ, Masterson B, McElroy S, Sethuraman G, Moore K, Kahwaty AM, Nelson D. PMID: 16169087.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. The illusion of mental health: in the mind of which beholder? J Pers Assess. 2005 Aug; 85(1):92-7. Joiner TE, Brown JS, Perez M, Sethuraman G, Sallee FR. PMID: 16083388.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    22. A retrospective comparison of cumulative time spent in remission during treatment with olanzapine or risperidone among patients with schizophrenia. Schizophr Res. 2005 Nov 15; 79(2-3):337-40. Sethuraman G, Taylor CC, Enerson M, Dunayevich E. PMID: 16054802.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    23. An Indian child with Kindler syndrome resulting from a new homozygous nonsense mutation (C468X) in the KIND1 gene. Clin Exp Dermatol. 2005 May; 30(3):286-8. Sethuraman G, Fassihi H, Ashton GH, Bansal A, Kabra M, Sharma VK, McGrath JA. PMID: 15807691.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    24. A pilot safety study of repetitive transcranial magnetic stimulation (rTMS) in Tourette's syndrome. Cogn Behav Neurol. 2004 Jun; 17(2):109-17. Chae JH, Nahas Z, Wassermann E, Li X, Sethuraman G, Gilbert D, Sallee FR, George MS. PMID: 15453520.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    25. The use of dietary supplements by veterans with cancer. J Altern Complement Med. 2004 Jun; 10(3):560-4. Jazieh AR, Kopp M, Foraida M, Ghouse M, Khalil M, Savidge M, Sethuraman G. PMID: 15253863.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    26. Breast milk feeding rates of mothers of multiples compared to mothers of singletons. Ambul Pediatr. 2004 May-Jun; 4(3):226-31. Geraghty SR, Pinney SM, Sethuraman G, Roy-Chaudhury A, Kalkwarf HJ. PMID: 15153054.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    27. Association of cortical disinhibition with tic, ADHD, and OCD severity in Tourette syndrome. Mov Disord. 2004 Apr; 19(4):416-25. Gilbert DL, Bansal AS, Sethuraman G, Sallee FR, Zhang J, Lipps T, Wassermann EM. PMID: 15077239.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    28. Tic reduction with risperidone versus pimozide in a randomized, double-blind, crossover trial. J Am Acad Child Adolesc Psychiatry. 2004 Feb; 43(2):206-14. Gilbert DL, Batterson JR, Sethuraman G, Sallee FR. PMID: 14726728.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCTClinical Trials
    29. Donors with central nervous system malignancies: are they truly safe? Transplantation. 2003 Jul 27; 76(2):340-3. Buell JF, Trofe J, Sethuraman G, Hanaway MJ, Beebe TM, Gross TG, Alloway R, First MR, Woodle ES. PMID: 12883189.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    30. Psychosocial outcomes of a pilot multidisciplinary program for weight management. Am J Health Behav. 2003 Jul-Aug; 27(4):348-54. Brehm BJ, Rourke KM, Cassell C, Sethuraman G. PMID: 12882428.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    31. Combination pharmacotherapy in children and adolescents with bipolar disorder. Biol Psychiatry. 2003 Jun 01; 53(11):978-84. Kowatch RA, Sethuraman G, Hume JH, Kromelis M, Weinberg WA. PMID: 12788243.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    32. Gemcitabine and Cisplatin is a highly effective combination chemotherapy in patients with advanced cancer of the gallbladder. Am J Clin Oncol. 2003 Apr; 26(2):174-7. Malik IA, Aziz Z, Zaidi SH, Sethuraman G. PMID: 12714891.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    33. Effect of weight change on bone mass in female adolescents. J Am Diet Assoc. 2003 Mar; 103(3):369-72. Rourke KM, Brehm BJ, Cassell C, Sethuraman G. PMID: 12616262.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. Tic reduction with pergolide in a randomized controlled trial in children. Neurology. 2003 Feb 25; 60(4):606-11. Gilbert DL, Dure L, Sethuraman G, Raab D, Lane J, Sallee FR. PMID: 12601100.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    35. Meta-analysis of EEG test performance shows wide variation among studies. Neurology. 2003 Feb 25; 60(4):564-70. Gilbert DL, Sethuraman G, Kotagal U, Buncher CR. PMID: 12601093.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    36. Neuroendocrine and behavioral responses to dopaminergic agonists in adolescents with alcohol abuse. Psychopharmacology (Berl). 2003 Mar; 166(2):95-101. Upadhyaya HP, Brady KT, Liao J, Sethuraman G, Middaugh L, Wharton M, Sallee FR. PMID: 12520313.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Phase II trial of sequential therapy with fludarabine followed by cyclophosphamide, mitoxantrone, vincristine, and prednisone for low-grade follicular lymphomas. Am J Hematol. 2002 Jul; 70(3):181-5. Rohatgi N, LaRocca RV, Bard V, Sethuraman G, Foon KA. PMID: 12111762.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    38. Pulmonary cysts consistent with lymphangioleiomyomatosis are common in women with tuberous sclerosis: genetic and radiographic analysis. Chest. 2002 Mar; 121(3 Suppl):61S. McCormack F, Brody A, Meyer C, Leonard J, Chuck G, Dabora S, Sethuraman G, Colby TV, Kwiatkowski DJ, Franz DN. PMID: 11893688.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    39. Mutational and radiographic analysis of pulmonary disease consistent with lymphangioleiomyomatosis and micronodular pneumocyte hyperplasia in women with tuberous sclerosis. Am J Respir Crit Care Med. 2001 Aug 15; 164(4):661-8. Franz DN, Brody A, Meyer C, Leonard J, Chuck G, Dabora S, Sethuraman G, Colby TV, Kwiatkowski DJ, McCormack FX. PMID: 11520734.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    40. Lamotrigine therapy of epilepsy in tuberous sclerosis. Epilepsia. 2001 Jul; 42(7):935-40. Franz DN, Tudor C, Leonard J, Egelhoff JC, Byars A, Valerius K, Sethuraman G. PMID: 11488895.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    41. Venlafaxine treatment of patients with comorbid alcohol/cocaine abuse and attention-deficit/hyperactivity disorder: a pilot study. J Clin Psychopharmacol. 2001 Feb; 21(1):116-8. Upadhyaya HP, Brady KT, Sethuraman G, Sonne SC, Malcolm R. PMID: 11199938.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    42. Fenfluramine challenge in anxious children. Hum Psychopharmacol. 2000 Dec; 15(8):619-629. Sallee FR, Vrindavanam NS, Liu H, Sethuraman G, Sine L. PMID: 12404615.
      View in: PubMed   Mentions: 1     Fields:    
    43. Yohimbine challenge in children with anxiety disorders. Am J Psychiatry. 2000 Aug; 157(8):1236-42. Sallee FR, Sethuraman G, Sine L, Liu H. PMID: 10910785.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    44. The dopamine D3 receptor antagonist nafadotride inhibits development of locomotor sensitization to amphetamine. Brain Res. 2000 Jun 09; 867(1-2):239-42. Richtand NM, Logue AD, Welge JA, Perdiue J, Tubbs LJ, Spitzer RH, Sethuraman G, Geracioti TD. PMID: 10837819.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    45. Tourette's syndrome improvement with pergolide in a randomized, double-blind, crossover trial. Neurology. 2000 Mar 28; 54(6):1310-5. Gilbert DL, Sethuraman G, Sine L, Peters S, Sallee FR. PMID: 10746603.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    46. Validation of an instrument to measure voice-related quality of life (V-RQOL). J Voice. 1999 Dec; 13(4):557-69. Hogikyan ND, Sethuraman G. PMID: 10622521.
      View in: PubMed   Mentions: 101     Fields:    Translation:Humans
    47. Parenteral clomipramine challenge in depressed adolescents: mood and neuroendocrine response. Biol Psychiatry. 1998 Oct 01; 44(7):562-7. Sallee FR, Vrindavanam NS, Deas-Nesmith D, Odom AM, Carson SW, Sethuraman G. PMID: 9787880.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    48. Intravenous clomipramine challenge in obsessive-compulsive disorder: predicting response to oral therapy at eight weeks. Biol Psychiatry. 1998 Aug 01; 44(3):220-7. Sallee FR, Koran LM, Pallanti S, Carson SW, Sethuraman G. PMID: 9693393.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    49. Clonidine challenge in childhood anxiety disorder. J Am Acad Child Adolesc Psychiatry. 1998 Jun; 37(6):655-62. Sallee FR, Richman H, Sethuraman G, Dougherty D, Sine L, Altman-Hamamdzic S. PMID: 9628086.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    50. Relative efficacy of haloperidol and pimozide in children and adolescents with Tourette's disorder. Am J Psychiatry. 1997 Aug; 154(8):1057-62. Sallee FR, Nesbitt L, Jackson C, Sine L, Sethuraman G. PMID: 9247389.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCTClinical Trials
    51. Pulse intravenous clomipramine for depressed adolescents: double-blind, controlled trial. Am J Psychiatry. 1997 May; 154(5):668-73. Sallee FR, Vrindavanam NS, Deas-Nesmith D, Carson SW, Sethuraman G. PMID: 9137123.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    52. Dopamine agonist treatment of Tourette disorder in children: results of an open-label trial of pergolide. Mov Disord. 1997 May; 12(3):402-7. Lipinski JF, Sallee FR, Jackson C, Sethuraman G. PMID: 9159736.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    53. Platelet serotonin transporter in children and adolescents with obsessive-compulsive disorder or Tourette's syndrome. J Am Acad Child Adolesc Psychiatry. 1996 Dec; 35(12):1647-56. Sallee FR, Richman H, Beach K, Sethuraman G, Nesbitt L. PMID: 8973072.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsCTClinical Trials
    54. Prolactin monitoring of haloperidol and pimozide treatment in children with Tourette's syndrome. Biol Psychiatry. 1996 Nov 15; 40(10):1044-50. Sallee FR, Dougherty D, Sethuraman G, Vrindavanam N. PMID: 8915564.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    55. Head growth in cocaine-exposed infants: relationship to neonate hair level. J Dev Behav Pediatr. 1995 Apr; 16(2):77-81. Sallee FR, Katikaneni LP, McArthur PD, Ibrahim HM, Nesbitt L, Sethuraman G. PMID: 7790518.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    56. Lymphocyte glucocorticoid receptor: predictor of sertraline response in adolescent major depressive disorder (MDD). Psychopharmacol Bull. 1995; 31(2):339-45. Sallee FR, Nesbitt L, Dougherty D, Hilal R, Nandagopal VS, Sethuraman G. PMID: 7491389.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    57. Effects of pimozide on cognition in children with Tourette syndrome: interaction with comorbid attention deficit hyperactivity disorder. Acta Psychiatr Scand. 1994 Jul; 90(1):4-9. Sallee FR, Sethuraman G, Rock CM. PMID: 7976448.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    58. Factors associated with visual loss in patients with advanced glaucomatous changes in the optic nerve head. Am J Ophthalmol. 1993 Aug 15; 116(2):176-81. Stewart WC, Chorak RP, Hunt HH, Sethuraman G. PMID: 8352302.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
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