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Frances J. Richmond, PhD

Title(s)Chair of the Department of Regulatory and Quality Sciences and Professor of Regulatory and Quality Sciences
Phone+1 323 442 3531
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    Dr. Frances Richmond was educated as a neurophysiologist (BNSc, MSc, PhD) at Queen's University (Kingston, Ontario). She completed post-doctoral studies at the Université de Montreal and the National Institutes of Health before joining the faculty of Queen's University, where she served as Associate Dean of Life Sciences (1986-1989). She also served as a policy advisor for scientific labor needs at Industry Canada (1990-1992) and as a clinical scientist at the Alfred E. Mann Foundation, an early stage device development group (1994-1995). She was the first female to be appointed Director of a research consortium funded by Canada's Medical Research Council (1995-2000).

    Dr. Richmond joined the faculty of USC in 1999 as Director of Regulatory and Clinical Sciences at the Alfred E. Mann Institute where she served for 8 years. Her work there included seven projects in the field of product development which have advanced through the clinical trial stage. Though focused mostly on the BION, an implantable wireless microstimulator, she was also involved in research on other implantables, sensors and prosthetic limbs. Dr. Richmond is or has been a member of three large research consortia (NIH Engineering Research partnership, NIH Bioengineering Research partnership, Clinical and Translational Science Institute). She directs the Regulatory Knowledge and Support group of the CSTI for the Los Angeles Basin.

    Since 1999 Dr. Richmond was a part-time faculty member of the School of Pharmacy, and transitioned to a full-time position in 2008. Dr Richmond is currently Director of the International Center for Regulatory Science, that provides certificate, MS and doctoral training in the regulatory management of foods, dietary supplements, medical devices and drugs. A major focus of the International Center is on global outreach and research related to regulation in emerging economies.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Church TD, Richmond FJ. Biobank Continuity Management: A Survey of Biobank Professionals. Biopreserv Biobank. 2019 Apr 24. PMID: 31017454.
      View in: PubMed
    2. Elser C, Richmond FJ. Validation Master Plans: Progress of Implementation in the Pharmaceutical Industry. Ther Innov Regul Sci. 2018 Jan 01; 2168479018784910. PMID: 29969918.
      View in: PubMed
    3. Fisher LM, Martinez AS, Richmond FJ, Krieger MD, Wilkinson EP, Eisenberg LS. Assessing the Benefit-Risk Profile for Pediatric Implantable Auditory Prostheses. Ther Innov Regul Sci. 2018 09; 52(5):669-679. PMID: 29714549.
      View in: PubMed
    4. Medina C, Richmond FJ. Incentivizing Quality in the Manufacture of Pharmaceuticals: Industry Views on Quality Metrics and Ratings. Ther Innov Regul Sci. 2015 Sep; 49(5):730-738. PMID: 30227034.
      View in: PubMed
    5. Storm NE, Richmond FJ. Global Regulatory Dissonance: A Case Study of Industry Views on the Development of Drugs for Postmenopausal Osteoporosis. Ther Innov Regul Sci. 2015 Mar; 49(2):269-278. PMID: 30222422.
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    6. Pfeiffer JP, Richmond FJ. Management of Clinical Trial Agreements: Current Practices of Investigators in the United States. Ther Innov Regul Sci. 2015 Jan; 49(1):139-145. PMID: 30222447.
      View in: PubMed
    7. Jamieson MW, Richmond FJ. The Role of Universities in the Commercialization of Medical Products: A Survey of Industry Views. Ther Innov Regul Sci. 2014 May; 48(3):347-356. PMID: 30235543.
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    8. Liao KC, Hogen-Esch T, Richmond FJ, Marcu L, Clifton W, Loeb GE. Percutaneous fiber-optic sensor for chronic glucose monitoring in vivo. Biosens Bioelectron. 2008 May 15; 23(10):1458-65. PMID: 18304798.
      View in: PubMed
    9. Loeb GE, Richmond FJ, Baker LL. The BION devices: injectable interfaces with peripheral nerves and muscles. Neurosurg Focus. 2006 May 15; 20(5):E2. PMID: 16711659.
      View in: PubMed
    10. Weber DJ, Stein RB, Chan KM, Loeb G, Richmond F, Rolf R, James K, Chong SL. BIONic WalkAide for correcting foot drop. IEEE Trans Neural Syst Rehabil Eng. 2005 Jun; 13(2):242-6. PMID: 16003906.
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    11. Weber DJ, Stein RB, Chan KM, Loeb GE, Richmond FJ, Rolf R, James K, Chong SL, Thompson AK, Misiaszek J. Functional electrical stimulation using microstimulators to correct foot drop: a case study. Can J Physiol Pharmacol. 2004 Aug-Sep; 82(8-9):784-92. PMID: 15523536.
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    12. Salter AC, Bagg SD, Creasy JL, Romano C, Romano D, Richmond FJ, Loeb GE. First Clinical Experience with BION Implants for Therapeutic Electrical Stimulation. Neuromodulation. 2004 Jan; 7(1):38-47. PMID: 22151125.
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    13. Loeb GE, Richmond FJ, Singh J, Peck RA, Tan W, Zou Q, Sachs N. RF-powered BIONs for stimulation and sensing. Conf Proc IEEE Eng Med Biol Soc. 2004; 6:4182-5. PMID: 17271225.
      View in: PubMed
    14. Weber DJ, Stein RB, Chan KM, Loeb GE, Richmond FJ, Rolf R, James K, Chong SL. BIONic WalkAide for correcting foot drop. Conf Proc IEEE Eng Med Biol Soc. 2004; 6:4189-92. PMID: 17271227.
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    15. Chih Liao K, Richmond F, Hogen-Esch T, Marcu L, Loeb GE. Senciltrade mark project: development of a percutaneous optical biosensor. Conf Proc IEEE Eng Med Biol Soc. 2004; 3:2082-5. PMID: 17272132.
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    16. Dupont Salter AC, Richmond FJ, Loeb GE. Prevention of muscle disuse atrophy by low-frequency electrical stimulation in rats. IEEE Trans Neural Syst Rehabil Eng. 2003 Sep; 11(3):218-26. PMID: 14518784.
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    17. Dupont Salter AC, Richmond FJ, Loeb GE. Effects of muscle immobilization at different lengths on tetrodotoxin-induced disuse atrophy. IEEE Trans Neural Syst Rehabil Eng. 2003 Sep; 11(3):209-17. PMID: 14518783.
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    18. Satoda T, Matsumoto H, Zhou L, Rose PK, Richmond FJ. Mesencephalic projections to the first cervical segment in the cat. Exp Brain Res. 2002 Jun; 144(3):397-413. PMID: 12021821.
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    19. May PJ, Warren S, Chen B, Richmond FJ, Olivier E. Midbrain reticular formation circuitry subserving gaze in the cat. Ann N Y Acad Sci. 2002 Apr; 956:405-8. PMID: 11960826.
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    20. Singh K, Melis EH, Richmond FJ, Scott SH. Morphometry of Macaca mulatta forelimb. II. Fiber-type composition in shoulder and elbow muscles. J Morphol. 2002 Mar; 251(3):323-32. PMID: 11835368.
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    21. Richmond FJ, Singh K, Corneil BD. Neck muscles in the rhesus monkey. I. Muscle morphometry and histochemistry. J Neurophysiol. 2001 Oct; 86(4):1717-28. PMID: 11600634.
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    22. Corneil BD, Olivier E, Richmond FJ, Loeb GE, Munoz DP. Neck muscles in the rhesus monkey. II. Electromyographic patterns of activation underlying postures and movements. J Neurophysiol. 2001 Oct; 86(4):1729-49. PMID: 11600635.
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    23. Dupont AC, Sauerbrei EE, Fenton PV, Shragge PC, Loeb GE, Richmond FJ. Real-time sonography to estimate muscle thickness: comparison with MRI and CT. J Clin Ultrasound. 2001 May; 29(4):230-6. PMID: 11323778.
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    24. Singh K, Richmond FJ, Loeb GE. Recruitment properties of intramuscular and nerve-trunk stimulating electrodes. IEEE Trans Rehabil Eng. 2000 Sep; 8(3):276-85. PMID: 11001507.
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    25. Richmond FJ, Liinamaa TA, Keane J, Thomson DB. Morphometry, histochemistry, and innervation of cervical shoulder muscles in the cat. J Morphol. 1999 Mar; 239(3):255-69. PMID: 10081153.
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    26. Richmond FJ, Singh K, Corneil BD. Marked non-uniformity of fiber-type composition in the primate suboccipital muscle obliquus capitis inferior. Exp Brain Res. 1999 Mar; 125(1):14-8. PMID: 10100971.
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    27. Richmond FJ, Corneil BD, Singh K. Animal models of motor systems: cautionary tales from studies of head movement. Prog Brain Res. 1999; 123:411-6. PMID: 10635736.
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    28. Cameron T, Liinamaa TL, Loeb GE, Richmond FJ. Long-term biocompatibility of a miniature stimulator implanted in feline hind limb muscles. IEEE Trans Biomed Eng. 1998 Aug; 45(8):1024-35. PMID: 9691577.
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    29. Cameron T, Richmond FJ, Loeb GE. Effects of regional stimulation using a miniature stimulator implanted in feline posterior biceps femoris. IEEE Trans Biomed Eng. 1998 Aug; 45(8):1036-43. PMID: 9691578.
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    30. Brown IE, Satoda T, Richmond FJ, Loeb GE. Feline caudofemoralis muscle. Muscle fibre properties, architecture, and motor innervation. Exp Brain Res. 1998 Jul; 121(1):76-91. PMID: 9698193.
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    31. Kamibayashi LK, Richmond FJ. Morphometry of human neck muscles. Spine (Phila Pa 1976). 1998 Jun 15; 23(12):1314-23. PMID: 9654620.
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    32. Runciman RJ, Richmond FJ. Shoulder and forelimb orientations and loading in sitting cats: implications for head and shoulder movement. J Biomech. 1997 Sep; 30(9):911-9. PMID: 9302614.
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    33. Graf W, Keshner E, Richmond FJ, Shinoda Y, Statler K, Uchino Y. How to construct and move a cat's neck. J Vestib Res. 1997 Mar-Jun; 7(2-3):219-37. PMID: 9178225.
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    34. Liinamaa TL, Keane J, Richmond FJ. Distribution of motoneurons supplying feline neck muscles taking origin from the shoulder girdle. J Comp Neurol. 1997 Jan 13; 377(2):298-312. PMID: 8986887.
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    35. Thomson DB, Loeb GE, Richmond FJ. Effect of neck posture on patterns of activation of feline neck muscles during horizontal rotation. Exp Brain Res. 1996 Aug; 110(3):392-400. PMID: 8871098.
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    36. Fitzpatrick TL, Liinamaa TL, Brown IE, Cameron T, Richmond FJ. A novel method to identify migration of small implantable devices. J Long Term Eff Med Implants. 1996; 6(3-4):157-68. PMID: 10172964.
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    37. Trotter JA, Richmond FJ, Purslow PP. Functional morphology and motor control of series-fibered muscles. Exerc Sport Sci Rev. 1995; 23:167-213. PMID: 7556350.
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    38. Smits E, Rose PK, Gordon T, Richmond FJ. Organization of single motor units in feline sartorius. J Neurophysiol. 1994 Oct; 72(4):1885-96. PMID: 7823107.
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    39. Thomson DB, Loeb GE, Richmond FJ. Effect of neck posture on the activation of feline neck muscles during voluntary head turns. J Neurophysiol. 1994 Oct; 72(4):2004-14. PMID: 7823114.
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    40. Kitamura S, Richmond FJ. Distribution of motoneurons supplying dorsal and ventral suboccipital muscles in the feline neck. J Comp Neurol. 1994 Sep 01; 347(1):25-35. PMID: 7798380.
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    41. Richmond FJ, Gladdy R, Creasy JL, Kitamura S, Smits E, Thomson DB. Efficacy of seven retrograde tracers, compared in multiple-labelling studies of feline motoneurones. J Neurosci Methods. 1994 Jul; 53(1):35-46. PMID: 7527476.
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    42. Selbie WS, Thomson DB, Richmond FJ. Sagittal-plane mobility of the cat cervical spine. J Biomech. 1993 Aug; 26(8):917-27. PMID: 8349717.
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    43. Heron MI, Richmond FJ. In-series fiber architecture in long human muscles. J Morphol. 1993 Apr; 216(1):35-45. PMID: 8496969.
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    44. Selbie WS, Thomson DB, Richmond FJ. Suboccipital muscles in the cat neck: morphometry and histochemistry of the rectus capitis muscle complex. J Morphol. 1993 Apr; 216(1):47-63. PMID: 8496970.
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    45. Abrahams VC, Kori AA, Loeb GE, Richmond FJ, Rose PK, Keirstead SA. Facial input to neck motoneurons: trigemino-cervical reflexes in the conscious and anaesthetised cat. Exp Brain Res. 1993; 97(1):23-30. PMID: 8131829.
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    46. Scott SH, Thomson DB, Richmond FJ, Loeb GE. Neuromuscular organization of feline anterior sartorius: II. Intramuscular length changes and complex length-tension relationships during stimulation of individual nerve branches. J Morphol. 1992 Aug; 213(2):171-83. PMID: 1518070.
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    47. Richmond FJ, Thomson DB, Loeb GE. Electromyographic studies of neck muscles in the intact cat. I. Patterns of recruitment underlying posture and movement during natural behaviors. Exp Brain Res. 1992; 88(1):41-58. PMID: 1541361.
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    48. Richmond FJ, Loeb GE. Electromyographic studies of neck muscles in the intact cat. II. Reflexes evoked by muscle nerve stimulation. Exp Brain Res. 1992; 88(1):59-66. PMID: 1541362.
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    49. Thomson DB, Scott SH, Richmond FJ. Neuromuscular organization of feline anterior sartorius: I. Asymmetric distribution of motor units. J Morphol. 1991 Nov; 210(2):147-62. PMID: 1836236.
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    50. Gordon DC, Loeb GE, Richmond FJ. Distribution of motoneurons supplying cat sartorius and tensor fasciae latae, demonstrated by retrograde multiple-labelling methods. J Comp Neurol. 1991 Feb 15; 304(3):357-72. PMID: 1708787.
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    51. Gordon DC, Richmond FJ. Distribution of motoneurons supplying dorsal suboccipital and intervertebral muscles in the cat neck. J Comp Neurol. 1991 Feb 15; 304(3):343-56. PMID: 2022754.
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    52. Gordon DC, Richmond FJ. Topography in the phrenic motoneuron nucleus demonstrated by retrograde multiple-labelling techniques. J Comp Neurol. 1990 Feb 15; 292(3):424-34. PMID: 2341610.
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    53. Gordon DC, Hammond CG, Fisher JT, Richmond FJ. Muscle-fiber architecture, innervation, and histochemistry in the diaphragm of the cat. J Morphol. 1989 Aug; 201(2):131-43. PMID: 2474663.
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    54. Hammond CG, Gordon DC, Fisher JT, Richmond FJ. Motor unit territories supplied by primary branches of the phrenic nerve. J Appl Physiol (1985). 1989 Jan; 66(1):61-71. PMID: 2917957.
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    55. Armstrong JB, Rose PK, Vanner S, Bakker GJ, Richmond FJ. Compartmentalization of motor units in the cat neck muscle, biventer cervicis. J Neurophysiol. 1988 Jul; 60(1):30-45. PMID: 3404221.
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    56. Richmond FJ, Armstrong JB. Fiber architecture and histochemistry in the cat neck muscle, biventer cervicis. J Neurophysiol. 1988 Jul; 60(1):46-59. PMID: 2969960.
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    57. Abrahams VC, Richmond FJ. Specialization of sensorimotor organization in the neck muscle system. Prog Brain Res. 1988; 76:125-35. PMID: 3064138.
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    58. Loeb GE, Yee WJ, Pratt CA, Chanaud CM, Richmond FJ. Cross-correlation of EMG reveals widespread synchronization of motor units during some slow movements in intact cats. J Neurosci Methods. 1987 Oct; 21(2-4):239-49. PMID: 3682877.
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    59. Loeb GE, Pratt CA, Chanaud CM, Richmond FJ. Distribution and innervation of short, interdigitated muscle fibers in parallel-fibered muscles of the cat hindlimb. J Morphol. 1987 Jan; 191(1):1-15. PMID: 3820310.
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    60. Richmond FJ, Bakker GJ, Bakker DA, Stacey MJ. The innervation of tandem muscle spindles in the cat neck. J Comp Neurol. 1986 Mar 22; 245(4):483-97. PMID: 2422225.
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    61. Bakker DA, Richmond FJ, Abrahams VC, Courville J. Patterns of primary afferent termination in the external cuneate nucleus from cervical axial muscles in the cat. J Comp Neurol. 1985 Nov 22; 241(4):467-79. PMID: 4078043.
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    62. Richmond FJ, MacGillis DR, Scott DA. Muscle-fiber compartmentalization in cat splenius muscles. J Neurophysiol. 1985 Apr; 53(4):868-85. PMID: 2582099.
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    63. Richmond FJ, Stuart DG. Distribution of sensory receptors in the flexor carpi radialis muscle of the cat. J Morphol. 1985 Jan; 183(1):1-13. PMID: 3156250.
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    64. Abrahams VC, Richmond FJ, Keane J. Projections from C2 and C3 nerves supplying muscles and skin of the cat neck: a study using transganglionic transport of horseradish peroxidase. J Comp Neurol. 1984 Nov 20; 230(1):142-54. PMID: 6096411.
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    65. Bakker DA, Richmond FJ, Abrahams VC. Central projections from cat suboccipital muscles: a study using transganglionic transport of horseradish peroxidase. J Comp Neurol. 1984 Sep 20; 228(3):409-21. PMID: 6480919.
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    66. Richmond FJ, Johnston WS, Baker RS, Steinbach MJ. Palisade endings in human extraocular muscles. Invest Ophthalmol Vis Sci. 1984 Apr; 25(4):471-6. PMID: 6706509.
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    67. Abrahams VC, Lynn B, Richmond FJ. Organization and sensory properties of small myelinated fibres in the dorsal cervical rami of the cat. J Physiol. 1984 Feb; 347:177-87. PMID: 6707955.
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    68. Bakker DA, Richmond FJ. Muscle spindle complexes in muscles around upper cervical vertebrae in the cat. J Neurophysiol. 1982 Jul; 48(1):62-74. PMID: 6214618.
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    69. Richmond FJ, Bakker DA. Anatomical organization and sensory receptor content of soft tissues surrounding upper cervical vertebrae in the cat. J Neurophysiol. 1982 Jul; 48(1):49-61. PMID: 6214617.
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    70. Richmond FJ, Courville J, Saint-Cyr JA. Spino-olivary projections from the upper cervical spinal cord: an experimental study using autoradiography and horseradish peroxidase. Exp Brain Res. 1982; 47(2):239-51. PMID: 7117449.
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    71. Rose PK, Richmond FJ. White-matter dendrites in the upper cervical spinal cord of the adult cat: a light and electron microscopic study. J Comp Neurol. 1981 Jun 20; 199(2):191-203. PMID: 7251939.
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    72. Bakker GJ, Richmond FJ. Two types of muscle spindles in cat neck muscles: a histochemical study of intrafusal fiber composition. J Neurophysiol. 1981 Jun; 45(6):973-86. PMID: 7252535.
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    73. Bakker DA, Richmond FJ. Distribution of receptors around neck vertebrae in the cat [proceedings]. J Physiol. 1980 Jan; 298:40P-41P. PMID: 6444671.
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    74. Abrahams VC, Anstee G, Richmond FJ, Rose PK. Neck muscle and trigeminal input to the upper cervical cord and lower medulla of the cat. Can J Physiol Pharmacol. 1979 Jun; 57(6):642-51. PMID: 226254.
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    75. Richmond FJ, Abrahams VC. Physiological properties of muscle spindles in dorsal neck muscles of the cat. J Neurophysiol. 1979 Mar; 42(2):604-17. PMID: 154558.
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    76. Richmond FJ, Abrahams VC. What are the proprioceptors of the neck? Prog Brain Res. 1979; 50:245-54. PMID: 162155.
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    77. Richmond FJ, Scott DA, Abrahams VC. Distribution of motoneurones to the neck muscles, biventer cervicis, splenius and complexus in the cat. J Comp Neurol. 1978 Oct 01; 181(3):451-63. PMID: 690273.
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    78. Lund JP, Richmond FJ, Touloumis C, Patry Y, Lamarre Y. The distribution of Golgi tendon organs and muscle spindles in masseter and temporalis muscles of the cat. Neuroscience. 1978; 3(2):259-70. PMID: 153483.
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    79. Richmond FJ. Physiological characteristics of neck muscle receptors in the cat [proceedings]. J Physiol. 1977 Oct; 272(1):67P-68P. PMID: 592161.
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    80. Richmond FJ, Anstee GC, Sherwin EA, Abrahams VC. Motor and sensory fibres of neck muscle nerves in the cat. Can J Physiol Pharmacol. 1976 Jun; 54(3):294-304. PMID: 953860.
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    81. Richmond FJ, Abrahams VC. Morphology and distribution of muscle spindles in dorsal muscles of the cat neck. J Neurophysiol. 1975 Nov; 38(6):1322-39. PMID: 1221076.
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    82. Richmond FJ, Abrahams VC. Morphology and enzyme histochemistry of dorsal muscles of the cat neck. J Neurophysiol. 1975 Nov; 38(6):1312-21. PMID: 176329.
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    83. Abrahams VC, Richmond F, Rose PK. Absence of monosynaptic reflex in dorsal neck muscles of the cat. Brain Res. 1975 Jul 04; 92(1):130-1. PMID: 1174939.
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    84. Abrahams VC, Richmond F, Rose PK. Proceedings: Proprioceptive and retinal afferent projections to the superior colliculus of the cat and their connexions to the tectospinal tract. J Physiol. 1974 Sep; 241(2):101P-102P. PMID: 4280440.
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