Frances J. Richmond, PhD

Title(s)Professor of Regulatory and Quality Sciences (Teaching Track) and Director of International Center for Regulatory Sciences
SchoolUSC School of Pharmacy
AddressCHP 140
Health Sciences Campus
Los Angeles CA 90089-9014
Phone+1 323 442 3531
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    Dr. Frances Richmond was educated as a neurophysiologist (BNSc, MSc, PhD) at Queen's University (Kingston, Ontario). She completed post-doctoral studies at the Université de Montreal and the National Institutes of Health before joining the faculty of Queen's University, where she served as Associate Dean of Life Sciences (1986-1989). She also served as a policy advisor for scientific labor needs at Industry Canada (1990-1992) and as a clinical scientist at the Alfred E. Mann Foundation, an early stage device development group (1994-1995). She was the first female to be appointed Director of a research consortium funded by Canada's Medical Research Council (1995-2000).

    Dr. Richmond joined the faculty of USC in 1999 as Director of Regulatory and Clinical Sciences at the Alfred E. Mann Institute where she served for 8 years. Her work there included seven projects in the field of product development which have advanced through the clinical trial stage. Though focused mostly on the BION, an implantable wireless microstimulator, she was also involved in research on other implantables, sensors and prosthetic limbs. Dr. Richmond is or has been a member of three large research consortia (NIH Engineering Research partnership, NIH Bioengineering Research partnership, Clinical and Translational Science Institute). She directs the Regulatory Knowledge and Support group of the CSTI for the Los Angeles Basin.

    Since 1999 Dr. Richmond was a part-time faculty member of the School of Pharmacy, and transitioned to a full-time position in 2008. Dr Richmond is currently Director of the International Center for Regulatory Science, that provides certificate, MS and doctoral training in the regulatory management of foods, dietary supplements, medical devices and drugs. A major focus of the International Center is on global outreach and research related to regulation in emerging economies.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Impact of non-binding FDA guidances on primary endpoint selection in Alzheimer's disease trials. Alzheimers Dement (N Y). 2022; 8(1):e12280. Yu JC, Hlávka JP, Joe E, Richmond FJ, Lakdawalla DN. PMID: 35356740; PMCID: PMC8943597.
      View in: PubMed   Mentions:
    2. Turning Neural Prosthetics Into Viable Products. Front Robot AI. 2021; 8:754114. Loeb GE, Richmond FJ. PMID: 34660704; PMCID: PMC8513865.
      View in: PubMed   Mentions:
    3. Graduate Training Capacity for Regulatory Professionals at US Universities: Are We Facing a Talent Crisis? Ther Innov Regul Sci. 2020 07; 54(4):947-952. Richmond FJ, Church TD. PMID: 31925701.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    4. Biobank Continuity Management: A Survey of Biobank Professionals. Biopreserv Biobank. 2019 Oct; 17(5):410-417. Church TD, Richmond FJ. PMID: 31017454.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Validation Master Plans: Progress of Implementation in the Pharmaceutical Industry. Ther Innov Regul Sci. 2019 05; 53(3):354-363. Elser C, Richmond FJ. PMID: 29969918.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Assessing the Benefit-Risk Profile for Pediatric Implantable Auditory Prostheses. Ther Innov Regul Sci. 2018 09; 52(5):669-679. Fisher LM, Martinez AS, Richmond FJ, Krieger MD, Wilkinson EP, Eisenberg LS. PMID: 29714549; PMCID: PMC5943182.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Incentivizing Quality in the Manufacture of Pharmaceuticals: Industry Views on Quality Metrics and Ratings. Ther Innov Regul Sci. 2015 Sep; 49(5):730-738. Medina C, Richmond FJ. PMID: 30227034.
      View in: PubMed   Mentions:    Fields:    
    8. Global Regulatory Dissonance: A Case Study of Industry Views on the Development of Drugs for Postmenopausal Osteoporosis. Ther Innov Regul Sci. 2015 Mar; 49(2):269-278. Storm NE, Richmond FJ. PMID: 30222422.
      View in: PubMed   Mentions:    Fields:    
    9. Management of Clinical Trial Agreements: Current Practices of Investigators in the United States. Ther Innov Regul Sci. 2015 Jan; 49(1):139-145. Pfeiffer JP, Richmond FJ. PMID: 30222447.
      View in: PubMed   Mentions:    Fields:    
    10. The Role of Universities in the Commercialization of Medical Products: A Survey of Industry Views. Ther Innov Regul Sci. 2014 May; 48(3):347-356. Jamieson MW, Richmond FJ. PMID: 30235543.
      View in: PubMed   Mentions:    Fields:    
    11. Percutaneous fiber-optic sensor for chronic glucose monitoring in vivo. Biosens Bioelectron. 2008 May 15; 23(10):1458-65. Liao KC, Hogen-Esch T, Richmond FJ, Marcu L, Clifton W, Loeb GE. PMID: 18304798.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    12. The BION devices: injectable interfaces with peripheral nerves and muscles. Neurosurg Focus. 2006 May 15; 20(5):E2. Loeb GE, Richmond FJ, Baker LL. PMID: 16711659.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    13. BIONic WalkAide for correcting foot drop. IEEE Trans Neural Syst Rehabil Eng. 2005 Jun; 13(2):242-6. Weber DJ, Stein RB, Chan KM, Loeb G, Richmond F, Rolf R, James K, Chong SL. PMID: 16003906.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    14. Functional electrical stimulation using microstimulators to correct foot drop: a case study. Can J Physiol Pharmacol. 2004 Aug-Sep; 82(8-9):784-92. Weber DJ, Stein RB, Chan KM, Loeb GE, Richmond FJ, Rolf R, James K, Chong SL, Thompson AK, Misiaszek J. PMID: 15523536.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. BIONic WalkAide for correcting foot drop. Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:4189-92. Weber DJ, Stein RB, Chan KM, Loeb GE, Richmond FJ, Rolf R, James K, Chong SL. PMID: 17271227.
      View in: PubMed   Mentions: 3     Fields:    
    16. RF-powered BIONs for stimulation and sensing. Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:4182-5. Loeb GE, Richmond FJ, Singh J, Peck RA, Tan W, Zou Q, Sachs N. PMID: 17271225.
      View in: PubMed   Mentions: 5     Fields:    
    17. First Clinical Experience with BION Implants for Therapeutic Electrical Stimulation. Neuromodulation. 2004 Jan; 7(1):38-47. Salter AC, Bagg SD, Creasy JL, Romano C, Romano D, Richmond FJ, Loeb GE. PMID: 22151125.
      View in: PubMed   Mentions: 6     Fields:    
    18. Senciltrade mark project: development of a percutaneous optical biosensor. Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:2082-5. Chih Liao K, Richmond F, Hogen-Esch T, Marcu L, Loeb GE. PMID: 17272132.
      View in: PubMed   Mentions: 1     Fields:    
    19. Effects of muscle immobilization at different lengths on tetrodotoxin-induced disuse atrophy. IEEE Trans Neural Syst Rehabil Eng. 2003 Sep; 11(3):209-17. Dupont Salter AC, Richmond FJ, Loeb GE. PMID: 14518783.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    20. Prevention of muscle disuse atrophy by low-frequency electrical stimulation in rats. IEEE Trans Neural Syst Rehabil Eng. 2003 Sep; 11(3):218-26. Dupont Salter AC, Richmond FJ, Loeb GE. PMID: 14518784.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    21. Mesencephalic projections to the first cervical segment in the cat. Exp Brain Res. 2002 Jun; 144(3):397-413. Satoda T, Matsumoto H, Zhou L, Rose PK, Richmond FJ. PMID: 12021821.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    22. Midbrain reticular formation circuitry subserving gaze in the cat. Ann N Y Acad Sci. 2002 Apr; 956:405-8. May PJ, Warren S, Chen B, Richmond FJ, Olivier E. PMID: 11960826.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    23. Morphometry of Macaca mulatta forelimb. II. Fiber-type composition in shoulder and elbow muscles. J Morphol. 2002 Mar; 251(3):323-32. Singh K, Melis EH, Richmond FJ, Scott SH. PMID: 11835368.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    24. Neck muscles in the rhesus monkey. II. Electromyographic patterns of activation underlying postures and movements. J Neurophysiol. 2001 Oct; 86(4):1729-49. Corneil BD, Olivier E, Richmond FJ, Loeb GE, Munoz DP. PMID: 11600635.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    25. Neck muscles in the rhesus monkey. I. Muscle morphometry and histochemistry. J Neurophysiol. 2001 Oct; 86(4):1717-28. Richmond FJ, Singh K, Corneil BD. PMID: 11600634.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    26. Real-time sonography to estimate muscle thickness: comparison with MRI and CT. J Clin Ultrasound. 2001 May; 29(4):230-6. Dupont AC, Sauerbrei EE, Fenton PV, Shragge PC, Loeb GE, Richmond FJ. PMID: 11323778.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimals
    27. Recruitment properties of intramuscular and nerve-trunk stimulating electrodes. IEEE Trans Rehabil Eng. 2000 Sep; 8(3):276-85. Singh K, Richmond FJ, Loeb GE. PMID: 11001507.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    28. Morphometry, histochemistry, and innervation of cervical shoulder muscles in the cat. J Morphol. 1999 Mar; 239(3):255-69. Richmond FJ, Liinamaa TA, Keane J, Thomson DB. PMID: 10081153.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    29. Marked non-uniformity of fiber-type composition in the primate suboccipital muscle obliquus capitis inferior. Exp Brain Res. 1999 Mar; 125(1):14-8. Richmond FJ, Singh K, Corneil BD. PMID: 10100971.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    30. Animal models of motor systems: cautionary tales from studies of head movement. Prog Brain Res. 1999; 123:411-6. Richmond FJ, Corneil BD, Singh K. PMID: 10635736.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    31. Long-term biocompatibility of a miniature stimulator implanted in feline hind limb muscles. IEEE Trans Biomed Eng. 1998 Aug; 45(8):1024-35. Cameron T, Liinamaa TL, Loeb GE, Richmond FJ. PMID: 9691577.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    32. Effects of regional stimulation using a miniature stimulator implanted in feline posterior biceps femoris. IEEE Trans Biomed Eng. 1998 Aug; 45(8):1036-43. Cameron T, Richmond FJ, Loeb GE. PMID: 9691578.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    33. Feline caudofemoralis muscle. Muscle fibre properties, architecture, and motor innervation. Exp Brain Res. 1998 Jul; 121(1):76-91. Brown IE, Satoda T, Richmond FJ, Loeb GE. PMID: 9698193.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    34. Morphometry of human neck muscles. Spine (Phila Pa 1976). 1998 Jun 15; 23(12):1314-23. Kamibayashi LK, Richmond FJ. PMID: 9654620.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    35. Shoulder and forelimb orientations and loading in sitting cats: implications for head and shoulder movement. J Biomech. 1997 Sep; 30(9):911-9. Runciman RJ, Richmond FJ. PMID: 9302614.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    36. Distribution of motoneurons supplying feline neck muscles taking origin from the shoulder girdle. J Comp Neurol. 1997 Jan 13; 377(2):298-312. Liinamaa TL, Keane J, Richmond FJ. PMID: 8986887.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    37. Effect of neck posture on patterns of activation of feline neck muscles during horizontal rotation. Exp Brain Res. 1996 Aug; 110(3):392-400. Thomson DB, Loeb GE, Richmond FJ. PMID: 8871098.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    38. A novel method to identify migration of small implantable devices. J Long Term Eff Med Implants. 1996; 6(3-4):157-68. Fitzpatrick TL, Liinamaa TL, Brown IE, Cameron T, Richmond FJ. PMID: 10172964.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    39. Effect of neck posture on the activation of feline neck muscles during voluntary head turns. J Neurophysiol. 1994 Oct; 72(4):2004-14. Thomson DB, Loeb GE, Richmond FJ. PMID: 7823114.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    40. Organization of single motor units in feline sartorius. J Neurophysiol. 1994 Oct; 72(4):1885-96. Smits E, Rose PK, Gordon T, Richmond FJ. PMID: 7823107.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    41. Efficacy of seven retrograde tracers, compared in multiple-labelling studies of feline motoneurones. J Neurosci Methods. 1994 Jul; 53(1):35-46. Richmond FJ, Gladdy R, Creasy JL, Kitamura S, Smits E, Thomson DB. PMID: 7527476.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    42. Sagittal-plane mobility of the cat cervical spine. J Biomech. 1993 Aug; 26(8):917-27. Selbie WS, Thomson DB, Richmond FJ. PMID: 8349717.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    43. In-series fiber architecture in long human muscles. J Morphol. 1993 Apr; 216(1):35-45. Heron MI, Richmond FJ. PMID: 8496969.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    44. Suboccipital muscles in the cat neck: morphometry and histochemistry of the rectus capitis muscle complex. J Morphol. 1993 Apr; 216(1):47-63. Selbie WS, Thomson DB, Richmond FJ. PMID: 8496970.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    45. Facial input to neck motoneurons: trigemino-cervical reflexes in the conscious and anaesthetised cat. Exp Brain Res. 1993; 97(1):23-30. Abrahams VC, Kori AA, Loeb GE, Richmond FJ, Rose PK, Keirstead SA. PMID: 8131829.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    46. Neuromuscular organization of feline anterior sartorius: II. Intramuscular length changes and complex length-tension relationships during stimulation of individual nerve branches. J Morphol. 1992 Aug; 213(2):171-83. Scott SH, Thomson DB, Richmond FJ, Loeb GE. PMID: 1518070.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    47. Electromyographic studies of neck muscles in the intact cat. II. Reflexes evoked by muscle nerve stimulation. Exp Brain Res. 1992; 88(1):59-66. Richmond FJ, Loeb GE. PMID: 1541362.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    48. Electromyographic studies of neck muscles in the intact cat. I. Patterns of recruitment underlying posture and movement during natural behaviors. Exp Brain Res. 1992; 88(1):41-58. Richmond FJ, Thomson DB, Loeb GE. PMID: 1541361.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    49. Neuromuscular organization of feline anterior sartorius: I. Asymmetric distribution of motor units. J Morphol. 1991 Nov; 210(2):147-62. Thomson DB, Scott SH, Richmond FJ. PMID: 1836236.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    50. Distribution of motoneurons supplying cat sartorius and tensor fasciae latae, demonstrated by retrograde multiple-labelling methods. J Comp Neurol. 1991 Feb 15; 304(3):357-72. Gordon DC, Loeb GE, Richmond FJ. PMID: 1708787.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    51. Distribution of motoneurons supplying dorsal suboccipital and intervertebral muscles in the cat neck. J Comp Neurol. 1991 Feb 15; 304(3):343-56. Gordon DC, Richmond FJ. PMID: 2022754.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    52. Topography in the phrenic motoneuron nucleus demonstrated by retrograde multiple-labelling techniques. J Comp Neurol. 1990 Feb 15; 292(3):424-34. Gordon DC, Richmond FJ. PMID: 2341610.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    53. Muscle-fiber architecture, innervation, and histochemistry in the diaphragm of the cat. J Morphol. 1989 Aug; 201(2):131-43. Gordon DC, Hammond CG, Fisher JT, Richmond FJ. PMID: 2474663.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    54. Motor unit territories supplied by primary branches of the phrenic nerve. J Appl Physiol (1985). 1989 Jan; 66(1):61-71. Hammond CG, Gordon DC, Fisher JT, Richmond FJ. PMID: 2917957.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    55. Compartmentalization of motor units in the cat neck muscle, biventer cervicis. J Neurophysiol. 1988 Jul; 60(1):30-45. Armstrong JB, Rose PK, Vanner S, Bakker GJ, Richmond FJ. PMID: 3404221.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    56. Fiber architecture and histochemistry in the cat neck muscle, biventer cervicis. J Neurophysiol. 1988 Jul; 60(1):46-59. Richmond FJ, Armstrong JB. PMID: 2969960.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    57. Cross-correlation of EMG reveals widespread synchronization of motor units during some slow movements in intact cats. J Neurosci Methods. 1987 Oct; 21(2-4):239-49. Loeb GE, Yee WJ, Pratt CA, Chanaud CM, Richmond FJ. PMID: 3682877.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    58. Distribution and innervation of short, interdigitated muscle fibers in parallel-fibered muscles of the cat hindlimb. J Morphol. 1987 Jan; 191(1):1-15. Loeb GE, Pratt CA, Chanaud CM, Richmond FJ. PMID: 3820310.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    59. Distribution of sensory receptors in the flexor carpi radialis muscle of the cat. J Morphol. 1985 Jan; 183(1):1-13. Richmond FJ, Stuart DG. PMID: 3156250.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    60. Projections from C2 and C3 nerves supplying muscles and skin of the cat neck: a study using transganglionic transport of horseradish peroxidase. J Comp Neurol. 1984 Nov 20; 230(1):142-54. Abrahams VC, Richmond FJ, Keane J. PMID: 6096411.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    61. Two types of muscle spindles in cat neck muscles: a histochemical study of intrafusal fiber composition. J Neurophysiol. 1981 Jun; 45(6):973-86. Bakker GJ, Richmond FJ. PMID: 7252535.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
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