Eugene Depasquale

Title(s)Assistant Professor of Clinical Medicine
SchoolKeck School of Medicine of Usc
Address1520 San Pablo St.
Health Sciences Campus
Los Angeles CA 90033
ORCID ORCID Icon0000-0002-0638-5218 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Haverford College, Haverford, PAB.A.05/2001Biology
    State University of New York, Downstate College of Medicine, Brooklyn, NYM.D.05/2005
    Yale University School of Medicine / Yale-New Haven Hospital, New Haven, CT06/2008Resident in Internal Medicine
    Yale University School of Medicine / Yale-New Haven Hospital, New Haven, CT06/2009Fellow in Advanced Heart Failure & Transplant Cardiology
    Yale University School of Medicine / Yale-New Haven Hospital, New Haven, CT06/2012Fellow in Cardiovascular Medicine
    Collapse Awards and Honors
    State University of New York, Downstate College of MedicineAlpha Omega Alpha
    International Society for Heart & Lung Transplantation2013Transplant Registry Early Career Award

    Collapse Overview 
    Collapse Overview
    Dr. Eugene DePasquale is the Medical Director of the Heart Failure, Heart Transplantation and Mechanical Circulatory Support Program at the University of Southern California. Dr. DePasquale received his M.D. degree from State University of New York, Downstate College of Medicine. He completed his Internal Medicine Residency, Fellowship in Cardiovascular Medicine, and a Fellowship in Advanced Heart Failure and Transplant Cardiology at the Yale-New Haven Hospital. At the same institution, he was Chief Cardiology Fellow, and completed an additional Fellowship with a focus in Inherited Cardiomyopathies with additional study at University College London.

    His research interests include heart transplantation and mechanical circulatory support outcomes, as well as studies of novel heart failure and cardiomyopathy therapies. Additional interests include noninvasive rejection surveillance as well as studies of novel heart failure and cardiomyopathy therapies, including hypertrophic cardiomyopathy.

    In addition, Dr. DePasquale has a strong interest in sports cardiology serves as a medical consultant for the Women’s Tennis Association and USC Athletics. He served as a medical consultant for the US Open Tennis Championships from 2003 to 2020. Additionally, he serves on a national committee for the United States Tennis Association.

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. New UNOS allocation system associated with no added benefit in waitlist outcomes and worse post-transplant survival in heart-kidney patients. J Heart Lung Transplant. 2023 Jun 30. Francke M, Wolfson AM, Fong MW, Nattiv J, Pandya K, Kawaguchi ES, Villalon S, Mroz M, Sertic A, Cochran A, Ackerman MA, Melendrez M, Cartus R, Johnston KA, Okonkwo K, Ferrall J, DePasquale EC, Lee R, Vaidya AS. PMID: 37394021.
      View in: PubMed   Mentions:    Fields:    
    2. Effect of the UNOS policy change on rates of rejection, infection, and hospital readmission following heart transplantation. J Heart Lung Transplant. 2023 May 20. Vaidya AS, Lee ES, Kawaguchi ES, DePasquale EC, Pandya KA, Fong MW, Nattiv J, Villalon S, Sertic A, Cochran A, Ackerman MA, Melendrez M, Cartus R, Johnston KA, Lee R, Wolfson AM. PMID: 37211332.
      View in: PubMed   Mentions:    Fields:    
    3. The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients. J Heart Lung Transplant. 2023 05; 42(5):e1-e141. Velleca A, Shullo MA, Dhital K, Azeka E, Colvin M, DePasquale E, Farrero M, García-Guereta L, Jamero G, Khush K, Lavee J, Pouch S, Patel J, Michaud CJ, Shullo MA, Schubert S, Angelini A, Carlos L, Mirabet S, Patel J, Pham M, Urschel S, Kim KH, Miyamoto S, Chih S, Daly K, Grossi P, Jennings DL, Kim IC, Lim HS, Miller T, Potena L, Velleca A, Eisen H, Bellumkonda L, Danziger-Isakov L, Dobbels F, Harkess M, Kim D, Lyster H, Peled Y, Reinhardt Z. PMID: 37080658.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    4. Assessing the Relationship Between Molecular Rejection and Parenchymal Injury in Heart Transplant Biopsies. Transplantation. 2022 11 01; 106(11):2205-2216. Madill-Thomsen KS, Reeve J, Aliabadi-Zuckermann A, Cadeiras M, Crespo-Leiro MG, Depasquale EC, Deng M, Goekler J, Kim DH, Kobashigawa J, Macdonald P, Potena L, Shah K, Stehlik J, Zuckermann A, Halloran PF. PMID: 35968995.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. UNOS policy change benefits high-priority patients without harming those at low priority. Am J Transplant. 2022 12; 22(12):2931-2941. Wolfson AM, DePasquale EC, Fong MW, Pandya K, Zhou L, Kawaguchi ES, Thomas SS, Vaidya AS. PMID: 35975656; PMCID: PMC10087391.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Two is better than one: when to consider multiorgan transplant. Curr Opin Organ Transplant. 2022 02 01; 27(1):86-91. Miklin DJ, Mendoza M, DePasquale EC. PMID: 34890379.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Effect of UNOS policy change and exception status request on outcomes in patients bridged to heart transplant with an intra-aortic balloon pump. Artif Organs. 2022 May; 46(5):838-849. Wolfson AM, DePasquale EC, Starnes VA, Cunningham M, Baker C, Lee R, Bowdish M, Fong MW, Rahman J, Pandya K, Lewinger JP, Kawaguchi ES, Vaidya AS. PMID: 34748232.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Many heart transplant biopsies currently diagnosed as no rejection have mild molecular antibody-mediated rejection-related changes. J Heart Lung Transplant. 2022 03; 41(3):334-344. Halloran PF, Madill-Thomsen K, Aliabadi-Zuckermann AZ, Cadeiras M, Crespo-Leiro MG, Depasquale EC, Deng M, Gökler J, Kim DH, Kobashigawa J, Macdonald P, Potena L, Shah K, Stehlik J, Zuckermann A. PMID: 34548198.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Acute ST-Segment Elevation Myocardial Infarction as Initial Presentation of Atypical Hemolytic-Uremic Syndrome. JACC Case Rep. 2021 Apr; 3(4):561-565. Chau E, Li S, Xu PZ, Li GX, Ghasem W, Weitz IC, DeClerck BK, DePasquale EC, Yaghmour B. PMID: 34317581; PMCID: PMC8302770.
      View in: PubMed   Mentions:
    10. Extrapulmonary manifestations of severe acute respiratory syndrome coronavirus-2 infection. J Med Virol. 2021 05; 93(5):2645-2653. Rosen HR, O'Connell C, Nadim MK, DeClerck B, Sheibani S, DePasquale E, Sanossian N, Blodget E, Blodget E, Angell T. PMID: 33090515; PMCID: PMC7675751.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCellsPHPublic Health
    11. Relapsing Polychondritis Requiring Orthotopic Heart Transplant Despite Coronary Artery Bypass and Surgical Aortic Valve Replacement. JACC Case Rep. 2020 Aug; 2(10):1527-1531. Bae D, Lum C, Chand R, DePasquale E, Nsair A, Ardehali R. PMID: 34317010; PMCID: PMC8302168.
      View in: PubMed   Mentions:
    12. 2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy: Executive summary. Heart Rhythm. 2019 11; 16(11):e373-e407. Towbin JA, McKenna WJ, Abrams DJ, Ackerman MJ, Calkins H, Darrieux FCC, Daubert JP, de Chillou C, DePasquale EC, Desai MY, Estes NAM, Hua W, Indik JH, Ingles J, James CA, John RM, Judge DP, Keegan R, Krahn AD, Link MS, Marcus FI, McLeod CJ, Mestroni L, Priori SG, Saffitz JE, Sanatani S, Shimizu W, van Tintelen JP, Wilde AAM, Zareba W. PMID: 31676023.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    13. 2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy. Heart Rhythm. 2019 11; 16(11):e301-e372. Towbin JA, McKenna WJ, Abrams DJ, Ackerman MJ, Calkins H, Darrieux FCC, Daubert JP, de Chillou C, DePasquale EC, Desai MY, Estes NAM, Hua W, Indik JH, Ingles J, James CA, John RM, Judge DP, Keegan R, Krahn AD, Link MS, Marcus FI, McLeod CJ, Mestroni L, Priori SG, Saffitz JE, Sanatani S, Shimizu W, van Tintelen JP, Wilde AAM, Zareba W. PMID: 31078652.
      View in: PubMed   Mentions: 207     Fields:    Translation:Humans
    14. Noninvasive detection of graft injury after heart transplant using donor-derived cell-free DNA: A prospective multicenter study. Am J Transplant. 2019 10; 19(10):2889-2899. Khush KK, Patel J, Pinney S, Kao A, Alharethi R, DePasquale E, Ewald G, Berman P, Kanwar M, Hiller D, Yee JP, Woodward RN, Hall S, Kobashigawa J. PMID: 30835940; PMCID: PMC6790566.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    15. An integrated molecular diagnostic report for heart transplant biopsies using an ensemble of diagnostic algorithms. J Heart Lung Transplant. 2019 06; 38(6):636-646. Parkes MD, Aliabadi AZ, Cadeiras M, Crespo-Leiro MG, Deng M, Depasquale EC, Goekler J, Kim DH, Kobashigawa J, Loupy A, Macdonald P, Potena L, Zuckermann A, Halloran PF. PMID: 30795962.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    16. Exploring the cardiac response to injury in heart transplant biopsies. JCI Insight. 2018 10 18; 3(20). Halloran PF, Reeve J, Aliabadi AZ, Cadeiras M, Crespo-Leiro MG, Deng M, Depasquale EC, Goekler J, Jouven X, Kim DH, Kobashigawa J, Loupy A, Macdonald P, Potena L, Zuckermann A, Parkes MD. PMID: 30333303; PMCID: PMC6237487.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    17. Understanding the Correlation Between DSA, Complement Activation, and Antibody-Mediated Rejection in Heart Transplant Recipients. Transplantation. 2018 10; 102(10):e431-e438. Zhang Q, Hickey M, Drogalis-Kim D, Zheng Y, Gjertson D, Cadeiras M, Khuu T, Baas AS, Depasquale EC, Halnon NJ, Perens G, Alejos J, Cruz D, Ali N, Shemin R, Kwon M, Fishbein MC, Ardehali A, Deng M, Reed EF. PMID: 29916988; PMCID: PMC6153056.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    18. Heart and heart-liver transplantation in adults with failing Fontan physiology. Clin Transplant. 2018 08; 32(8):e13329. Reardon LC, DePasquale EC, Tarabay J, Cruz D, Laks H, Biniwale RM, Busuttil RW, Kaldas FM, Saab S, Venick RS, Lin JP, Nsair A, Deng MC, Ardehali A, Caderias M, Iygengar A, Aboulhosn JA. PMID: 29947122.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    19. Predicting the Future of Cardiac Allograft Vasculopathy With Cardiac Positron Emission Tomography: Ready for Prime Time? Circ Heart Fail. 2018 06; 11(6):e005136. DePasquale EC. PMID: 29891739.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Primary graft dysfunction in heart transplantation. Curr Opin Organ Transplant. 2018 06; 23(3):286-294. DePasquale EC, Ardehali A. PMID: 29553954.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    21. Prognostic utility of MELD-XI in adult congenital heart disease patients undergoing cardiac transplantation. Clin Transplant. 2018 06; 32(6):e13257. Adams ED, Jackson NJ, Young T, DePasquale EC, Reardon LC. PMID: 29660764.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    22. Clinical phenomapping and outcomes after heart transplantation. J Heart Lung Transplant. 2018 08; 37(8):956-966. Bakir M, Jackson NJ, Han SX, Bui A, Chang E, Liem DA, Ardehali A, Ardehali R, Baas AS, Press MC, Cruz D, Deng MC, DePasquale EC, Fonarow GC, Khuu T, Kwon MH, Kubak BM, Nsair A, Phung JL, Reed EF, Schaenman JM, Shemin RJ, Zhang QJ, Tseng CH, Cadeiras M. PMID: 29802085; PMCID: PMC6064662.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    23. Emerging pharmacologic and structural therapies for hypertrophic cardiomyopathy. Heart Fail Rev. 2017 11; 22(6):879-888. Philipson DJ, DePasquale EC, Yang EH, Baas AS. PMID: 28856513.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    24. ISHLT Transplant Registry: Youthful Investment-The Path to Progress. J Heart Lung Transplant. 2017 10; 36(10):1027-1036. Kransdorf EP, Mehta HS, Shah KB, Vucicevic D, DePasquale EC, Goldraich L, Ciarka A, Masetti M, Youn JC, Irving C, Khaliel F, Schweiger M, Uber P, Mehra MR, Stehlik J. PMID: 28942781.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. Cardiac Amyloidosis: Diagnosis and Treatment Strategies. Curr Oncol Rep. 2017 Jul; 19(7):46. Tuzovic M, Yang EH, Baas AS, Depasquale EC, Deng MC, Cruz D, Vorobiof G. PMID: 28528458.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    26. Socioeconomic Disparities in Heart Transplantation: A Universal Fix? Circ Cardiovasc Qual Outcomes. 2016 11; 9(6):693-694. DePasquale EC, Kobashigawa JA. PMID: 27803092.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    27. Temporary Venoarterial Extracorporeal Membrane Oxygenation: Ten-Year Experience at a Cardiac Transplant Center. J Intensive Care Med. 2018 May; 33(5):288-295. Tran BG, De La Cruz K, Grant S, Meltzer J, Benharash P, Dave R, Ardehali A, Shemin R, Depasquale E, Nsair A. PMID: 27302906.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Survival After Heart Transplantation in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy. J Card Fail. 2017 Feb; 23(2):107-112. DePasquale EC, Cheng RK, Deng MC, Nsair A, McKenna WJ, Fonarow GC, Jacoby DL. PMID: 27154489.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    29. Heart Failure Therapies for End-Stage Chemotherapy-Induced Cardiomyopathy. J Card Fail. 2016 Jun; 22(6):439-48. Mukku RB, Fonarow GC, Watson KE, Ajijola OA, Depasquale EC, Nsair A, Baas AS, Deng MC, Yang EH. PMID: 27109619.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    30. Familial dilated cardiomyopathy diagnosis is commonly overlooked at the time of transplant listing. J Heart Lung Transplant. 2016 Apr; 35(4):474-80. Seidelmann SB, Laur O, Hwa J, Depasquale E, Bellumkonda L, Sugeng L, Pomianowski P, Testani J, Chen M, McKenna W, Jacoby D. PMID: 26852066; PMCID: PMC5423783.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    31. Team-Based Care for Outpatients with Heart Failure. Heart Fail Clin. 2015 Jul; 11(3):379-405. Creaser JW, DePasquale EC, Vandenbogaart E, Rourke D, Chaker T, Fonarow GC. PMID: 26142637.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    32. Anomalous left coronary artery in hypertrophic cardiomyopathy. Ann Thorac Surg. 2014 Jun; 97(6):2190-3. Penciu OM, Mojibian H, Sugeng L, Cleman M, Brennan J, DePasquale E, McKenna W, Bonde P, Jacoby D. PMID: 24882306.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. A contemporary review of adult heart transplantation: 2012 to 2013. J Heart Lung Transplant. 2014 Aug; 33(8):775-84. DePasquale EC, Schweiger M, Ross HJ. PMID: 24954884.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    34. Management of ACCF/AHA Stage C heart failure. Cardiol Clin. 2014 Feb; 32(1):73-93, viii. Adigopula S, Vivo RP, DePasquale EC, Nsair A, Deng MC. PMID: 24286580.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    35. Impact of atrial fibrillation on outcomes in heart failure. Heart Fail Clin. 2013 Oct; 9(4):437-49, viii. DePasquale EC, Fonarow GC. PMID: 24054477.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Obesity in heart failure: impact on survival and treatment modalities. Expert Rev Cardiovasc Ther. 2013 Sep; 11(9):1141-53. Cheng RK, DePasquale EC, Deng MC, Nsair A, Horwich TB. PMID: 23944985.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    37. Hypertrophic cardiomyopathy: diagnosis, risk stratification and treatment. CMAJ. 2013 Feb 05; 185(2):127-34. Jacoby DL, DePasquale EC, McKenna WJ. PMID: 23109605; PMCID: PMC3563885.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    38. Outcomes of adults with restrictive cardiomyopathy after heart transplantation. J Heart Lung Transplant. 2012 Dec; 31(12):1269-75. DePasquale EC, Nasir K, Jacoby DL. PMID: 23079066.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    39. Assessment of myocardial viability: review of the clinical significance. Rev Cardiovasc Med. 2008; 9(4):225-31. Ramos M, DePasquale E, Coplan NL. PMID: 19122580.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
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