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Eric James Kezirian, MD, MPH

TitleProfessor of Clinical Otolaryngology-Head & Neck Surgery
InstitutionUniversity of Southern California
DepartmentOtolaryngology
AddressCHP 204M 1540 Alcazar Street
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 442 5790
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    Other Positions
    TitleVice Chair of the Caruso Department of Otolaryngology-Head & Neck Surgery


    Collapse Biography 
    Collapse Awards and Honors
    American Academy of Otolaryngology - Head and Neck Surgery2013Distinguished Service Award
    American Academy of Otolaryngology - Head and Neck Surgery2008Honor Award
    University of Pennsylvania School of Medicine1997Joel Gordon Miller Award
    University of Pennsylvania1996Alpha Omega Alpha
    1995Charles A. Lauffer Foundation Scholarship
    1992Rotary Foundation Ambassadorial Scholarship
    Harvard College1992Magna cum laude
    Harvard College1989  - 1992Harvard College Scholarship

    Collapse Overview 
    Collapse Overview
    Eric J. Kezirian, MD, MPH is Professor of Sleep Medicine in the USC Caruso Department of Otolaryngology - Head & Neck Surgery. Dr. Kezirian is a leader in the surgical treatment of snoring and obstructive sleep apnea and is the President of the International Surgical Sleep Society, the premiere organization in the field. He is the only surgeon in Southern California with a primary clinical and research focus in sleep surgery.

    Dr. Kezirian utilizes a wide array of procedures and the latest research, including his own, to provide his patients with the most appropriate, effective treatment plan. His research has addressed the most important questions in the field, including how surgeons should choose procedures, how well surgery works, and the development of new surgical techniques and novel therapies. This work has been supported by the National Institutes of Health and other organizations. Dr. Kezirian has led a number of major clinical trials, and he has many active research studies.

    After graduating magna cum laude from Harvard College, he obtained a Master of Science degree from the University of Oxford and then received his medical degree from the University of Pennsylvania. During his residency training in otolaryngology-head and neck surgery at the University of Washington, Dr. Kezirian received a Master of Public Health degree. Following his fellowship in sleep surgery at Stanford University, he joined the faculty at the University of California, San Francisco. There Dr. Kezirian was the director of the Division of Sleep Surgery in the Department of Otolaryngology—Head and Neck Surgery prior to coming to USC.

    Dr. Kezirian is Board-certified both in otolaryngology-head & neck surgery and sleep medicine.

    More information about Dr. Kezirian's research and clinical work can be found on his website: www.sleep-doctor.com.


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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Mah CD, Kezirian EJ, Marcello BM, Dement WC. Poor sleep quality and insufficient sleep of a collegiate student-athlete population. Sleep Health. 2018 Jun; 4(3):251-257. PMID: 29776619.
      View in: PubMed
    2. Li HY, Lee LA, Kezirian EJ, Nakayama M. Suspension Palatoplasty for Obstructive Sleep Apnea- A Preliminary Study. Sci Rep. 2018 Mar 09; 8(1):4224. PMID: 29523819.
      View in: PubMed
    3. Boon M, Huntley C, Steffen A, Maurer JT, Sommer JU, Schwab R, Thaler E, Soose R, Chou C, Strollo P, Kezirian EJ, Chia S, Withrow K, Weidenbecher M, Strohl K, Doghramji K, Hofauer B, Heiser C. Upper Airway Stimulation for Obstructive Sleep Apnea: Results from the ADHERE Registry. Otolaryngol Head Neck Surg. 2018 Mar 01; 194599818764896. PMID: 29557280.
      View in: PubMed
    4. Irvine LE, Yang Z, Kezirian EJ, Nimni ME, Han B. Hyoepiglottic ligament collagen and elastin fiber composition and changes associated with aging. Laryngoscope. 2018 May; 128(5):1245-1248. PMID: 29330863.
      View in: PubMed
    5. Ravesloot MJL, Benoist L, van Maanen P, Kezirian EJ, de Vries N. Advances in the Diagnosis of Obstructive Sleep Apnea: Drug-Induced Sleep Endoscopy. Adv Otorhinolaryngol. 2017; 80:22-27. PMID: 28738362.
      View in: PubMed
    6. Genta PR, Sands SA, Butler JP, Loring SH, Katz ES, Demko BG, Kezirian EJ, White DP, Wellman A. Airflow Shape Is Associated With the Pharyngeal Structure Causing OSA. Chest. 2017 09; 152(3):537-546. PMID: 28651794.
      View in: PubMed
    7. Ong AA, Ayers CM, Kezirian EJ, Tucker Woodson B, de Vries N, Nguyen SA, Boyd Gillespie M. Application of drug-induced sleep endoscopy in patients treated with upper airway stimulation therapy. World J Otorhinolaryngol Head Neck Surg. 2017 Jun; 3(2):92-96. PMID: 29204585.
      View in: PubMed
    8. Brietzke SE, Ishman SL, Cohen S, Cyr DD, Shin JJ, Kezirian EJ. National Database Analysis of Single-Level versus Multilevel Sleep Surgery. Otolaryngol Head Neck Surg. 2017 May; 156(5):955-961. PMID: 28322112.
      View in: PubMed
    9. Durr ML, Meyer AK, Kezirian EJ, Mamlouk MD, Frieden IJ, Rosbe KW. Sleep-disordered breathing in pediatric head and neck vascular malformations. Laryngoscope. 2017 Sep; 127(9):2159-2164. PMID: 28092114.
      View in: PubMed
    10. Charakorn N, Kezirian EJ. Drug-Induced Sleep Endoscopy. Otolaryngol Clin North Am. 2016 Dec; 49(6):1359-1372. PMID: 27720169.
      View in: PubMed
    11. Kezirian EJ. Acclimation settings with identical or similar sensation and functional thresholds. Laryngoscope. 2016 Sep; 126 Suppl 7:S20-1. PMID: 27480341.
      View in: PubMed
    12. Chung F, Memtsoudis SG, Ramachandran SK, Nagappa M, Opperer M, Cozowicz C, Patrawala S, Lam D, Kumar A, Joshi GP, Fleetham J, Ayas N, Collop N, Doufas AG, Eikermann M, Englesakis M, Gali B, Gay P, Hernandez AV, Kaw R, Kezirian EJ, Malhotra A, Mokhlesi B, Parthasarathy S, Stierer T, Wappler F, Hillman DR, Auckley D. Society of Anesthesia and Sleep Medicine Guidelines on Preoperative Screening and Assessment of Adult Patients With Obstructive Sleep Apnea. Anesth Analg. 2016 08; 123(2):452-73. PMID: 27442772; PMCID: PMC4956681.
    13. Li HY, Lee LA, Kezirian EJ. Efficacy of Coblation Endoscopic Lingual Lightening in Multilevel Surgery for Obstructive Sleep Apnea. JAMA Otolaryngol Head Neck Surg. 2016 05 01; 142(5):438-43. PMID: 26987105.
      View in: PubMed
    14. Friedman NR, Prager JD, Ruiz AG, Kezirian EJ. A Pediatric Grading Scale for Lingual Tonsil Hypertrophy. Otolaryngol Head Neck Surg. 2016 Jan; 154(1):171-4. PMID: 26307581.
      View in: PubMed
    15. Pietzsch JB, Liu S, Garner AM, Kezirian EJ, Strollo PJ. Long-Term Cost-Effectiveness of Upper Airway Stimulation for the Treatment of Obstructive Sleep Apnea: A Model-Based Projection Based on the STAR Trial. Sleep. 2015 May 01; 38(5):735-44. PMID: 25348126; PMCID: PMC4402668.
    16. Li HY, Lee LA, Kezirian EJ. Coblation endoscopic lingual lightening (CELL) for obstructive sleep apnea. Eur Arch Otorhinolaryngol. 2016 Jan; 273(1):231-6. PMID: 25577994.
      View in: PubMed
    17. Kezirian EJ. Does my tongue look fat? Sleep. 2014 Oct 01; 37(10):1583-4. PMID: 25197800; PMCID: PMC4173913.
    18. Kezirian EJ. Surgical Evaluation in Obstructive Sleep Apnea: Climbing the Steep Part of the Learning Curve. JAMA Otolaryngol Head Neck Surg. 2014 Jun; 140(6):568. PMID: 24788943.
      View in: PubMed
    19. Goepfert RP, Kezirian EJ, Wang SJ. Oral tongue squamous cell carcinoma in young women: a matched comparison-do outcomes justify treatment intensity? ISRN Otolaryngol. 2014; 2014:529395. PMID: 24734200; PMCID: PMC3964833.
    20. Capasso R, Kezirian E, Jacobowitz O, Weaver EM. Management of obstructive sleep apnea in adults. Ann Intern Med. 2014 Mar 04; 160(5):367. PMID: 24589933.
      View in: PubMed
    21. Kezirian EJ, Goding GS, Malhotra A, O'Donoghue FJ, Zammit G, Wheatley JR, Catcheside PG, Smith PL, Schwartz AR, Walsh JH, Maddison KJ, Claman DM, Huntley T, Park SY, Campbell MC, Palme CE, Iber C, Eastwood PR, Hillman DR, Barnes M. Hypoglossal nerve stimulation improves obstructive sleep apnea: 12-month outcomes. J Sleep Res. 2014 Feb; 23(1):77-83. PMID: 24033656; PMCID: PMC4323268.
    22. Heaton CM, Chazen JL, van Zante A, Glastonbury CM, Kezirian EJ, Eisele DW. Pleomorphic adenoma of the major salivary glands: diagnostic utility of FNAB and MRI. Laryngoscope. 2013 Dec; 123(12):3056-60. PMID: 23798340.
      View in: PubMed
    23. Vroegop AV, Vanderveken OM, Wouters K, Hamans E, Dieltjens M, Michels NR, Hohenhorst W, Kezirian EJ, Kotecha BT, de Vries N, Braem MJ, Van de Heyning PH. Observer variation in drug-induced sleep endoscopy: experienced versus nonexperienced ear, nose, and throat surgeons. Sleep. 2013 Jun 01; 36(6):947-53. PMID: 23729939; PMCID: PMC3649836.
    24. Kezirian EJ. SKUP3: a major step forward in sleep surgery research. Thorax. 2013 Sep; 68(9):801-2. PMID: 23716074.
      View in: PubMed
    25. Chang JL, Kezirian EJ. What are the health risks of untreated snoring without obstructive sleep apnea? Laryngoscope. 2013 Jun; 123(6):1321-2. PMID: 23553233.
      View in: PubMed
    26. Kezirian EJ, Chang JL. Snoring without OSA and health consequences: the jury is still out. Sleep. 2013 Apr 01; 36(4):613. PMID: 23565009; PMCID: PMC3612260.
    27. Durr ML, van Zante A, Li D, Kezirian EJ, Wang SJ. Oral tongue squamous cell carcinoma in never-smokers: analysis of clinicopathologic characteristics and survival. Otolaryngol Head Neck Surg. 2013 Jul; 149(1):89-96. PMID: 23533221.
      View in: PubMed
    28. Khan A, Harrison SL, Kezirian EJ, Ancoli-Israel S, O'Hearn D, Orwoll E, Redline S, Ensrud K, Stone KL. Obstructive sleep apnea during rapid eye movement sleep, daytime sleepiness, and quality of life in older men in Osteoporotic Fractures in Men (MrOS) Sleep Study. J Clin Sleep Med. 2013 Mar 15; 9(3):191-8. PMID: 23493839; PMCID: PMC3578688.
    29. Jáuregui EJ, Calkins SM, Kezirian EJ. Heterotopic ossification and delayed foreign body reaction after hyoid suspension for obstructive sleep apnea. Otolaryngol Head Neck Surg. 2013 Mar; 148(3):527-8. PMID: 23151835.
      View in: PubMed
    30. George JR, Chung S, Nielsen I, Goldberg AN, Miller A, Kezirian EJ. Comparison of drug-induced sleep endoscopy and lateral cephalometry in obstructive sleep apnea. Laryngoscope. 2012 Nov; 122(11):2600-5. PMID: 23086863; PMCID: PMC3484185.
    31. Durr ML, Meyer AK, Kezirian EJ, Rosbe KW. Drug-induced sleep endoscopy in persistent pediatric sleep-disordered breathing after adenotonsillectomy. Arch Otolaryngol Head Neck Surg. 2012 Jul; 138(7):638-43. PMID: 22801887.
      View in: PubMed
    32. Kezirian EJ, Hussey HM, Brietzke SE, Cohen SM, Davis GE, Shin JJ, Weinberger DG, Cabana MD. Hypopharyngeal surgery in obstructive sleep apnea: practice patterns, perceptions, and attitudes. Otolaryngol Head Neck Surg. 2012 Nov; 147(5):964-71. PMID: 22753614.
      View in: PubMed
    33. Goding GS, Tesfayesus W, Kezirian EJ. Hypoglossal nerve stimulation and airway changes under fluoroscopy. Otolaryngol Head Neck Surg. 2012 Jun; 146(6):1017-22. PMID: 22307575.
      View in: PubMed
    34. Schwartz AR, Barnes M, Hillman D, Malhotra A, Kezirian E, Smith PL, Hoegh T, Parrish D, Eastwood PR. Acute upper airway responses to hypoglossal nerve stimulation during sleep in obstructive sleep apnea. Am J Respir Crit Care Med. 2012 Feb 15; 185(4):420-6. PMID: 22135343; PMCID: PMC3297092.
    35. Rosenbluth KH, Kwiat DA, Harrison MR, Kezirian EJ. Hyoid bone advancement for improving airway patency: cadaver study of a magnet-based system. Otolaryngol Head Neck Surg. 2012 Mar; 146(3):491-6. PMID: 22114308.
      View in: PubMed
    36. Eastwood PR, Barnes M, Walsh JH, Maddison KJ, Hee G, Schwartz AR, Smith PL, Malhotra A, McEvoy RD, Wheatley JR, O'Donoghue FJ, Rochford PD, Churchward T, Campbell MC, Palme CE, Robinson S, Goding GS, Eckert DJ, Jordan AS, Catcheside PG, Tyler L, Antic NA, Worsnop CJ, Kezirian EJ, Hillman DR. Treating obstructive sleep apnea with hypoglossal nerve stimulation. Sleep. 2011 Nov 01; 34(11):1479-86. PMID: 22043118; PMCID: PMC3198202.
    37. Beaudreau SA, Spira AP, Stewart A, Kezirian EJ, Lui LY, Ensrud K, Redline S, Ancoli-Israel S, Stone KL. Validation of the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale in older black and white women. Sleep Med. 2012 Jan; 13(1):36-42. PMID: 22033120; PMCID: PMC3586742.
    38. Spira AP, Beaudreau SA, Stone KL, Kezirian EJ, Lui LY, Redline S, Ancoli-Israel S, Ensrud K, Stewart A. Reliability and validity of the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale in older men. J Gerontol A Biol Sci Med Sci. 2012 Apr; 67(4):433-9. PMID: 21934125; PMCID: PMC3309871.
    39. Mah CD, Mah KE, Kezirian EJ, Dement WC. The effects of sleep extension on the athletic performance of collegiate basketball players. Sleep. 2011 Jul 01; 34(7):943-50. PMID: 21731144; PMCID: PMC3119836.
    40. Kezirian EJ, Hohenhorst W, de Vries N. Drug-induced sleep endoscopy: the VOTE classification. Eur Arch Otorhinolaryngol. 2011 Aug; 268(8):1233-1236. PMID: 21614467.
      View in: PubMed
    41. Kezirian EJ. Nonresponders to pharyngeal surgery for obstructive sleep apnea: insights from drug-induced sleep endoscopy. Laryngoscope. 2011 Jun; 121(6):1320-6. PMID: 21557231; PMCID: PMC3100447.
    42. Kim EY, Courey MS, Kezirian EJ. Treatment of trigger-point hypersensitivity of gag reflex following surgical treatment of obstructive sleep apnea. Otolaryngol Head Neck Surg. 2011 Dec; 145(6):1055-6. PMID: 21531868.
      View in: PubMed
    43. Kezirian EJ, Weaver EM, Criswell MA, de Vries N, Woodson BT, Piccirillo JF. Reporting results of obstructive sleep apnea syndrome surgery trials. Otolaryngol Head Neck Surg. 2011 Apr; 144(4):496-9. PMID: 21493223.
      View in: PubMed
    44. Kezirian EJ, Maselli J, Vittinghoff E, Goldberg AN, Auerbach AD. Obstructive sleep apnea surgery practice patterns in the United States: 2000 to 2006. Otolaryngol Head Neck Surg. 2010 Sep; 143(3):441-7. PMID: 20723785; PMCID: PMC2924589.
    45. Kim EY, Eisele DW, Goldberg AN, Maselli J, Kezirian EJ. Neck dissections in the United States from 2000 to 2006: volume, indications, and regionalization. Head Neck. 2011 Jun; 33(6):768-73. PMID: 20737497; PMCID: PMC2994973.
    46. Kezirian EJ, Malhotra A, Goldberg AN, White DP. Changes in obstructive sleep apnea severity, biomarkers, and quality of life after multilevel surgery. Laryngoscope. 2010 Jul; 120(7):1481-8. PMID: 20564750.
      View in: PubMed
    47. Kezirian EJ, White DP, Malhotra A, Ma W, McCulloch CE, Goldberg AN. Interrater reliability of drug-induced sleep endoscopy. Arch Otolaryngol Head Neck Surg. 2010 Apr; 136(4):393-7. PMID: 20403857.
      View in: PubMed
    48. Kezirian EJ, Boudewyns A, Eisele DW, Schwartz AR, Smith PL, Van de Heyning PH, De Backer WA. Electrical stimulation of the hypoglossal nerve in the treatment of obstructive sleep apnea. Sleep Med Rev. 2010 Oct; 14(5):299-305. PMID: 20116305.
      View in: PubMed
    49. Eastwood PR, Malhotra A, Palmer LJ, Kezirian EJ, Horner RL, Ip MS, Thurnheer R, Antic NA, Hillman DR. Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions. Respirology. 2010 May; 15(4):587-95. PMID: 20136736; PMCID: PMC4342116.
    50. Eskiizmir G, Kezirian E. Is there a vicious cycle between obstructive sleep apnea and laryngopharyngeal reflux disease? Med Hypotheses. 2009 Nov; 73(5):706-8. PMID: 19493631.
      View in: PubMed
    51. Rodriguez-Bruno K, Goldberg AN, McCulloch CE, Kezirian EJ. Test-retest reliability of drug-induced sleep endoscopy. Otolaryngol Head Neck Surg. 2009 May; 140(5):646-51. PMID: 19393404; PMCID: PMC2845469.
    52. Kezirian EJ, Harrison SL, Ancoli-Israel S, Redline S, Ensrud K, Goldberg AN, Claman DM, Spira AP, Stone KL. Behavioral correlates of sleep-disordered breathing in older men. Sleep. 2009 Feb; 32(2):253-61. PMID: 19238813; PMCID: PMC2635590.
    53. Kezirian EJ, Kirisoglu CE, Riley RW, Chang E, Guilleminault C, Powell NB. Resting energy expenditure in adults with sleep disordered breathing. Arch Otolaryngol Head Neck Surg. 2008 Dec; 134(12):1270-5. PMID: 19075121.
      View in: PubMed
    54. Kezirian EJ, Harrison SL, Ancoli-Israel S, Redline S, Ensrud K, Claman DM, Stone KL. Behavioral correlates of sleep-disordered breathing in older women. Sleep. 2007 Sep; 30(9):1181-8. PMID: 17910390; PMCID: PMC1978407.
    55. Kezirian EJ, Weaver EM, Yueh B, Khuri SF, Daley J, Henderson WG. Risk factors for serious complication after uvulopalatopharyngoplasty. Arch Otolaryngol Head Neck Surg. 2006 Oct; 132(10):1091-8. PMID: 17043257.
      View in: PubMed
    56. Farwell DG, Kezirian EJ, Heydt JL, Yueh B, Futran ND. Efficacy of small reconstruction plates in vascularized bone graft mandibular reconstruction. Head Neck. 2006 Jul; 28(7):573-9. PMID: 16755584.
      View in: PubMed
    57. Kezirian EJ, Goldberg AN. Hypopharyngeal surgery in obstructive sleep apnea: an evidence-based medicine review. Arch Otolaryngol Head Neck Surg. 2006 Feb; 132(2):206-13. PMID: 16490881.
      View in: PubMed
    58. Kezirian EJ, Powell NB, Riley RW, Hester JE. Incidence of complications in radiofrequency treatment of the upper airway. Laryngoscope. 2005 Jul; 115(7):1298-304. PMID: 15995525.
      View in: PubMed
    59. Bowden MT, Kezirian EJ, Utley D, Goode RL. Outcomes of hyoid suspension for the treatment of obstructive sleep apnea. Arch Otolaryngol Head Neck Surg. 2005 May; 131(5):440-5. PMID: 15897424.
      View in: PubMed
    60. Kamdar BB, Kaplan KA, Kezirian EJ, Dement WC. The impact of extended sleep on daytime alertness, vigilance, and mood. Sleep Med. 2004 Sep; 5(5):441-8. PMID: 15341888.
      View in: PubMed
    61. Kezirian EJ, Weaver EM, Yueh B, Deyo RA, Khuri SF, Daley J, Henderson W. Incidence of serious complications after uvulopalatopharyngoplasty. Laryngoscope. 2004 Mar; 114(3):450-3. PMID: 15091217.
      View in: PubMed
    62. Kezirian EJ, Yueh B. Introduction to cost analysis in facial plastic surgery. Facial Plast Surg. 2002 May; 18(2):95-9. PMID: 12063656.
      View in: PubMed
    63. Kezirian EJ, Yueh B. Accuracy of terminology and methodology in economic analyses in otolaryngology. Otolaryngol Head Neck Surg. 2001 May; 124(5):496-502. PMID: 11337651.
      View in: PubMed
    64. Kezirian EJ, White KR, Yueh B, Sullivan SD. Cost and cost-effectiveness of universal screening for hearing loss in newborns. Otolaryngol Head Neck Surg. 2001 Apr; 124(4):359-67. PMID: 11283492.
      View in: PubMed
    65. Tufano J, Conrad DA, Sales A, Maynard C, Noren J, Kezirian E, Schellhase KG, Liang SY. Effects of compensation method on physician behaviors. Am J Manag Care. 2001 Apr; 7(4):363-73. PMID: 11310191.
      View in: PubMed
    66. Kezirian EJ, Alsarraf R, Lykins C, Futran ND. Imaging quiz case 3. Cervical tuberculous lymphadenopathy (scrofula). Arch Otolaryngol Head Neck Surg. 2000 Dec; 126(12):1501,1504-5. PMID: 11115293.
      View in: PubMed
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