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Danieli B. Salinas, MD

Title(s)Associate Professor of Clinical Pediatrics
Address4640 West Sunset Boulevard
Off Campus
Los Angeles CA 90027
Phone+1 323 361 2101
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    I am originally from Rio de Janeiro, Brazil and I came to the U.S. for Residency and Fellowship training in Pediatric Pulmonology with the goal of becoming a physician scientist. My passion is Cystic Fibrosis. I enjoy taking care of these complex children and I am fascinated by the science behind the consequences of this defective chloride channel. The fact that we still don’t have a cure for this disease and that there are nearly 2,000 different mutations producing a wide range of clinical presentations are my biggest motivation to work in this field. I hope to make contributions to improve the lives of people with this disease and I hope I can one day say CF stands for Cure Found! My major areas of research interest are predicting clinical outcomes in children with a positive newborn screening for Cystic Fibrosis.
    a. Retrospective study based on the California database.
    b. Hierarchical modeling of clinical prediction.
    c. Developing a Sweat Rate test for infants for more accurately diagnose CF and predict clinical outcome.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Abnormal Lung Clearance Index in Cystic Fibrosis Screen Positive, Inconclusive Diagnosis (CFSPID) Children with Otherwise Normal FEV1. Lung. 2020 02; 198(1):163-167. Kasi AS, Wee CP, Keens TG, Salinas DB. PMID: 31844968.
      View in: PubMed   Mentions:    Fields:    
    2. Image-based ß-adrenergic sweat rate assay captures minimal cystic fibrosis transmembrane conductance regulator function. Pediatr Res. 2020 01; 87(1):137-145. Salinas DB, Peng YH, Horwich B, Wee CP, Frisbee E, Maarek JM. PMID: 31344706.
      View in: PubMed   Mentions:    Fields:    
    3. Inconclusive diagnosis after a positive newborn bloodspot screening result for cystic fibrosis; clarification of the harmonised international definition. J Cyst Fibros. 2019 11; 18(6):778-780. Southern KW, Barben J, Gartner S, Munck A, Castellani C, Mayell SJ, Davies JC, Winters V, Murphy J, Salinas D, McColley SA, Ren CL, Farrell PM. PMID: 31027826.
      View in: PubMed   Mentions:    Fields:    
    4. The increasing challenge of genetic counseling for cystic fibrosis. J Cyst Fibros. 2019 03; 18(2):167-174. Foil KE, Powers A, Raraigh KS, Wallis K, Southern KW, Salinas D. PMID: 30527892.
      View in: PubMed   Mentions: 1     Fields:    
    5. Low Beta-Adrenergic Sweat Responses in Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator-Related Metabolic Syndrome Children. Pediatr Allergy Immunol Pulmonol. 2017 Mar 01; 30(1):2-6. Salinas DB, Kang L, Azen C, Quinton P. PMID: 28465863.
      View in: PubMed   Mentions:
    6. Applying Cystic Fibrosis Transmembrane Conductance Regulator Genetics and CFTR2 Data to Facilitate Diagnoses. J Pediatr. 2017 02; 181S:S27-S32.e1. Sosnay PR, Salinas DB, White TB, Ren CL, Farrell PM, Raraigh KS, Girodon E, Castellani C. PMID: 28129809.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    7. Phenotypes of California CF Newborn Screen-Positive Children with CFTR 5T Allele by TG Repeat Length. Genet Test Mol Biomarkers. 2016 Sep; 20(9):496-503. Salinas DB, Azen C, Young S, Keens TG, Kharrazi M, Parad RB. PMID: 27447098.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    8. Benign and Deleterious Cystic Fibrosis Transmembrane Conductance Regulator Mutations Identified by Sequencing in Positive Cystic Fibrosis Newborn Screen Children from California. PLoS One. 2016; 11(5):e0155624. Salinas DB, Sosnay PR, Azen C, Young S, Raraigh KS, Keens TG, Kharrazi M. PMID: 27214204.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    9. Benign outcome among positive cystic fibrosis newborn screen children with non-CF-causing variants. J Cyst Fibros. 2015 Nov; 14(6):714-9. Salinas DB, Sosnay PR, Azen C, Young S, Raraigh KS, Keens TG, Kharrazi M. PMID: 25824995.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    10. Novel CFTR variants identified during the first 3 years of cystic fibrosis newborn screening in California. J Mol Diagn. 2013 Sep; 15(5):710-22. Prach L, Koepke R, Kharrazi M, Keiles S, Salinas DB, Reyes MC, Pian M, Opsimos H, Otsuka KN, Hardy KA, Milla CE, Zirbes JM, Chipps B, O'Bra S, Saeed MM, Sudhakar R, Lehto S, Nielson D, Shay GF, Seastrand M, Jhawar S, Nickerson B, Landon C, Thompson A, Nussbaum E, Chin T, Wojtczak H. PMID: 23810505.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansPHPublic Health
    11. Hyperacidity of secreted fluid from submucosal glands in early cystic fibrosis. Am J Physiol Cell Physiol. 2006 Mar; 290(3):C741-9. Song Y, Salinas D, Nielson DW, Verkman AS. PMID: 16207791.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimals
    12. Submucosal gland dysfunction as a primary defect in cystic fibrosis. FASEB J. 2005 Mar; 19(3):431-3. Salinas D, Haggie PM, Thiagarajah JR, Song Y, Rosbe K, Finkbeiner WE, Nielson DW, Verkman AS. PMID: 15596485.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    13. Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy. J Gen Physiol. 2004 Aug; 124(2):125-37. Muanprasat C, Sonawane ND, Salinas D, Taddei A, Galietta LJ, Verkman AS. PMID: 15277574.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansAnimalsCells
    14. Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models. J Biol Chem. 2004 Sep 24; 279(39):40629-33. Song Y, Sonawane ND, Salinas D, Qian L, Pedemonte N, Galietta LJ, Verkman AS. PMID: 15280357.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    15. CFTR involvement in nasal potential differences in mice and pigs studied using a thiazolidinone CFTR inhibitor. Am J Physiol Lung Cell Mol Physiol. 2004 Nov; 287(5):L936-43. Salinas DB, Pedemonte N, Muanprasat C, Finkbeiner WF, Nielson DW, Verkman AS. PMID: 15246976.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
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