Loading...

Dan Ruderman, PhD

Title(s)Assistant Professor of Research Medicine
Address2250 Alcazar St. Ste. CSC-243
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 442 2839
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of California, BerkeleyB.S.05/1989Physics
    University of California , BerkeleyPh.D.10/1993Physics
    Cambridge University, Cambridge, UKPostdoctoral10/1995Visual neuroscience
    USCPostdoctoral10/1996Visual neuroscience
    The Salk Institute, La Jolla, CAPostdoctoral8/1998Visual neuroscience
    Collapse Awards and Honors
    Phi Beta Kappa1988Elected Member, Junior year
    U.C. Berkeley1988President's Undergraduate Fellowship
    Fannie and John Hertz Foundation 1989  - 1993Fellowship
    National Science Foundation1993Fellowship
    National Science Foundation/ North Atlantic Treaty Organization1994Postdoctoral Fellowship
    Alfred E. Sloan Foundation1996  - 1998Postdoctoral Fellowship

    Collapse Overview 
    Collapse Overview
    Dan Ruderman received his doctorate in theoretical physics from the University of California at Berkeley, followed by postdoctoral research at Cambridge University, USC, and the Salk Institute. Dr. Ruderman continued his scientific research in the industrial setting, first in solid tumor target discovery through integrative genomics at Berlex Biosciences, and then in proteomic biomarker discovery at Applied Minds.

    He was Founding Scientist at Applied Proteomics, a biomarker company spun out from Applied Minds in 2007. Dr. Ruderman joined CAMM in 2011, where his research focuses on signaling dynamics in cancer cells and systems biology interpretations of high-dimensional cancer assays, such as gene expression, proteomics, and autoantibodies.

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Websites
    Collapse In The News
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Deep learned tissue "fingerprints" classify breast cancers by ER/PR/Her2 status from H&E images. Sci Rep. 2020 Apr 29; 10(1):7275. Rawat RR, Ortega I, Roy P, Sha F, Shibata D, Ruderman D, Agus DB. PMID: 32350370.
      View in: PubMed   Mentions:    Fields:    
    2. Monitoring dynamic cytotoxic chemotherapy response in castration-resistant prostate cancer using plasma cell-free DNA (cfDNA). BMC Res Notes. 2019 May 15; 12(1):275. Patsch K, Matasci N, Soundararajan A, Diaz P, Agus DB, Ruderman D, Gross ME. PMID: 31092276.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Correlating nuclear morphometric patterns with estrogen receptor status in breast cancer pathologic specimens. NPJ Breast Cancer. 2018; 4:32. Rawat RR, Ruderman D, Macklin P, Rimm DL, Agus DB. PMID: 30211313.
      View in: PubMed   Mentions:
    4. mTORC2 contributes to the metabolic reprogramming in EGFR tyrosine-kinase inhibitor resistant cells in non-small cell lung cancer. Cancer Lett. 2018 10 10; 434:152-159. Chiang CT, Demetriou AN, Ung N, Choudhury N, Ghaffarian K, Ruderman DL, Mumenthaler SM. PMID: 30036610.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Image-Based Tracking of Heterogeneous Single-Cell Phenotypes. Methods Mol Biol. 2018; 1745:47-63. Patsch K, Mumenthaler SM, Ruderman D. PMID: 29476462.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. The emergence of dynamic phenotyping. Cell Biol Toxicol. 2017 12; 33(6):507-509. Ruderman D. PMID: 28942588.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Designing Successful Proteomics Experiments. Methods Mol Biol. 2017; 1550:271-288. Ruderman D. PMID: 28188536.
      View in: PubMed   Mentions:    Fields:    
    8. Single cell dynamic phenotyping. Sci Rep. 2016 10 06; 6:34785. Patsch K, Chiu CL, Engeln M, Agus DB, Mallick P, Mumenthaler SM, Ruderman D. PMID: 27708391.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. Epigenetic changes mediated by polycomb repressive complex 2 and E2a are associated with drug resistance in a mouse model of lymphoma. Genome Med. 2016 05 04; 8(1):54. Flinders C, Lam L, Rubbi L, Ferrari R, Fitz-Gibbon S, Chen PY, Thompson M, Christofk H, B Agus D, Ruderman D, Mallick P, Pellegrini M. PMID: 27146673.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    10. Intracellular kinetics of the androgen receptor shown by multimodal Image Correlation Spectroscopy (mICS). Sci Rep. 2016 Mar 03; 6:22435. Chiu CL, Patsch K, Cutrale F, Soundararajan A, Agus DB, Fraser SE, Ruderman D. PMID: 26936218.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. A cross-platform toolkit for mass spectrometry and proteomics. Nat Biotechnol. 2012 Oct; 30(10):918-20. Chambers MC, Maclean B, Burke R, Amodei D, Ruderman DL, Neumann S, Gatto L, Fischer B, Pratt B, Egertson J, Hoff K, Kessner D, Tasman N, Shulman N, Frewen B, Baker TA, Brusniak MY, Paulse C, Creasy D, Flashner L, Kani K, Moulding C, Seymour SL, Nuwaysir LM, Lefebvre B, Kuhlmann F, Roark J, Rainer P, Detlev S, Hemenway T, Huhmer A, Langridge J, Connolly B, Chadick T, Holly K, Eckels J, Deutsch EW, Moritz RL, Katz JE, Agus DB, MacCoss M, Tabb DL, Mallick P. PMID: 23051804.
      View in: PubMed   Mentions: 352     Fields:    Translation:Humans
    12. Anterior gradient 2 (AGR2): blood-based biomarker elevated in metastatic prostate cancer associated with the neuroendocrine phenotype. Prostate. 2013 Feb 15; 73(3):306-15. Kani K, Malihi PD, Jiang Y, Wang H, Wang Y, Ruderman DL, Agus DB, Mallick P, Gross ME. PMID: 22911164.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    13. Naphthenic acids as indicators of crude oil biodegradation in soil, based on semi-quantitative electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun Mass Spectrom. 2008 Dec; 22(23):3968-76. Hughey CA, Minardi CS, Galasso-Roth SA, Paspalof GB, Mapolelo MM, Rodgers RP, Marshall AG, Ruderman DL. PMID: 19003816.
      View in: PubMed   Mentions: 1     Fields:    Translation:CellsPHPublic Health
    14. IFN-beta-regulated genes show abnormal expression in therapy-naïve relapsing-remitting MS mononuclear cells: gene expression analysis employing all reported protein-protein interactions. J Neuroimmunol. 2008 Mar; 195(1-2):116-20. Yamaguchi KD, Ruderman DL, Croze E, Wagner TC, Velichko S, Reder AT, Salamon H. PMID: 18279974.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    15. The ubiquitin-conjugating enzyme E2-EPF is overexpressed in primary breast cancer and modulates sensitivity to topoisomerase II inhibition. Neoplasia. 2007 Jul; 9(7):601-13. Tedesco D, Zhang J, Trinh L, Lalehzadeh G, Meisner R, Yamaguchi KD, Ruderman DL, Dinter H, Zajchowski DA. PMID: 17710163.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    16. Translation-invariant orientation tuning in visual "complex" cells could derive from intradendritic computations. J Neurosci. 1998 Jun 01; 18(11):4325-34. Mel BW, Ruderman DL, Archie KA. PMID: 9592109.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    Daniel's Networks
    Concepts (120)
    Derived automatically from this person's publications.
    _
    Co-Authors (9)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _