Charles Kaplan, PhD

Title(s)Research Professor of Social Work
AddressATT T1400
Off Campus
Los Angeles CA 90089-1400
Phone+1 213 821 6633
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    Although a medical sociologist by training, Dr. Charles Kaplan has sought a balance between social work, sociology and social epidemiology during the course of his prolific research career exploring the patterns of drug use, drug treatment strategies and social policy. His path to the USC School of Social Work can only be described as multidisciplinary and can be traced back to his undergraduate days as a political science major at Tulane University. Kaplan found he was less interested in diplomacy or international relations and more attracted to sociology, particularly after taking a seminar on the subject during his senior year. Drawn to the social upheaval occurring in 1960s California, he headed to UCLA to earn a master’s degree and doctorate in sociology.

    During his time at UCLA, he received training in biomedical research through the National Institute of General Medical Science and began examining the connection between brain function and language, one of the first efforts to link neuroscience and sociology. His experiences in the lab sparked an interest in drug abuse and addiction, then a nascent field in terms of research. After a few years as an assistant professor at Rutgers University, Kaplan accepted an invitation to participate in an exchange program with Frankfurt University.

    Europe was just beginning to experience the effects of the heroin epidemic when Kaplan arrived. Due to his previous sociological experience and interest in drug addiction, he quickly gained traction studying the patterns and spread of illicit substance use. Kaplan later joined the Department of Social Psychiatry of Erasmus University in Rotterdam and established the Addiction Research Institute before taking a position as research professor at Maastricht University, where he led the Drug Abuse Research Division of the International Institute for Psychosocial and Socioecological Research. In addition to exploring the spread of heroin throughout Germany, he became interested in differing treatment standards and drug policies among European countries, eventually exploring various community approaches and residential treatment care methods in 13 nations—then the largest funded research project in Europe on drug addiction.

    Despite spending much of his academic career in Europe, Kaplan began to feel a pull back to the United States. The U.S. government had expressed growing interest in supporting research on drug use and minority populations, and Kaplan also met Dr. Avelardo Valdez, then a professor at University of Texas at San Antonio, during a conference in Europe. He began spending summers in Texas, and eventually retired from his European position and transitioned to the University of Houston with Valdez. Appointed associate dean of research, Kaplan began to build up the university’s research profile while continuing to explore the social epidemiology of drug use and its health and social consequences among minorities and special populations, such as evacuees from Hurricane Katrina and gang members.

    In 2011, he joined the USC School of Social Work—along with Valdez and another member of the Houston research team, Dr. Alice Cepeda—and took on a joint role as research professor and associate dean of research. In addition to his administrative responsibilities, Kaplan is keen to continue exploring the preclinical patterns of drug use with his research team, including the emergence of crack cocaine in Mexico City and the impact of the drug wars on Latino communities. He plans to involve students in his field-intensive research and further integrate the PhD program into research activities, in addition to developing a research cluster on drug and social policy with Valdez, Cepeda and other researchers.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Ambivalence: A Key to Clinical Trial Participation? Front Oncol. 2018; 8:300. Chilton JA, Rasmus ML, Lytton J, Kaplan CD, Jones LA, Hurd TC. PMID: 30148115.
      View in: PubMed   Mentions:
    2. Predicting the Mental Health and Functioning of Torture Survivors. J Nerv Ment Dis. 2018 01; 206(1):33-39. Song SJ, Subica A, Kaplan C, Tol W, de Jong J. PMID: 28350563.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Stages of Change Model has Limited Value in Explaining the Change in Use of Cannabis among Adolescent Participants in an Efficacious Motivational Interviewing Intervention. J Psychoactive Drugs. 2017 Nov-Dec; 49(5):363-372. Dupont HB, Candel MJJM, Lemmens P, Kaplan CD, van de Mheen D, De Vries NK. PMID: 28548619.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Building trust and diversity in patient-centered oncology clinical trials: An integrated model. Clin Trials. 2017 Apr; 14(2):170-179. Hurd TC, Kaplan CD, Cook ED, Chilton JA, Lytton JS, Hawk ET, Jones LA. PMID: 28166647.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    5. Drug Initiation of Female Detainees in a Compulsory Drug Treatment Institution in China. J Psychoactive Drugs. 2016 Nov-Dec; 48(5):393-401. Liu L, Hsiao SC, Kaplan C. PMID: 27705089.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Predicting Levels of Policy Advocacy Engagement Among Acute-Care Health Professionals. Policy Polit Nurs Pract. 2016 Feb; 17(1):43-55. Jansson BS, Nyamathi A, Heidemann G, Bird M, Ward CR, Brown-Saltzman K, Duan L, Kaplan C. PMID: 27151835.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Assessing the Efficacy of MOTI-4 for Reducing the Use of Cannabis Among Youth in the Netherlands: A Randomized Controlled Trial. J Subst Abuse Treat. 2016 06; 65:6-12. Dupont HB, Candel MJ, Kaplan CD, van de Mheen D, de Vries NK. PMID: 26780988.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    8. Validation of the Policy Advocacy Engagement Scale for frontline healthcare professionals. Nurs Ethics. 2017 May; 24(3):362-375. Jansson BS, Nyamathi A, Heidemann G, Duan L, Kaplan C. PMID: 26396141.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Mother-Youth Acculturation Gaps and Health-Risking/Emotional Problems among Latin-American Adolescents. Span J Psychol. 2015 Jul 20; 18:E52. Wiesner M, Arbona C, Capaldi DM, Kim HK, Kaplan CD. PMID: 26190068.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Effectiveness of lifestyle interventions to reduce binge eating symptoms in African American and Hispanic women. Appetite. 2015 Dec; 95:269-74. Mama SK, Schembre SM, O'Connor DP, Kaplan CD, Bode S, Lee RE. PMID: 26188275.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    11. Emerging patterns of crack use in Mexico City. Int J Drug Policy. 2015 Aug; 26(8):739-45. Valdez A, Kaplan C, Nowotny KM, Natera-Rey G, Cepeda A. PMID: 26003928.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. The stepped treatment engagement protocol for homeless, needle exchange heroin-dependent patients. J Addict Med. 2015 Mar-Apr; 9(2):163-4. Tringale R, Subica AM, Danielian A, Kaplan C. PMID: 25807454.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Predicting Patient Advocacy Engagement: A Multiple Regression Analysis Using Data From Health Professionals in Acute-Care Hospitals. Soc Work Health Care. 2015; 54(7):559-81. Jansson BS, Nyamathi A, Heidemann G, Duan L, Kaplan C. PMID: 26317762.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Validation of the patient advocacy engagement scale for health professionals. Res Nurs Health. 2015 Apr; 38(2):162-72. Jansson BS, Nyamathi A, Duan L, Kaplan C, Heidemann G, Ananias D. PMID: 25556351.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Psychological distress in torture survivors: pre- and post-migration risk factors in a US sample. Soc Psychiatry Psychiatr Epidemiol. 2015 Apr; 50(4):549-60. Song SJ, Kaplan C, Tol WA, Subica A, de Jong J. PMID: 25403567.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    16. The application of the rapid assessment and response methodology for cannabis prevention research among youth in the Netherlands. Int J Drug Policy. 2015 Aug; 26(8):731-8. Dupont HB, Kaplan CD, Braam RV, Verbraeck HT, de Vries NK. PMID: 25481612.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Migration among individuals with leprosy: a population-based study in central Brazil. Cad Saude Publica. 2014 Mar; 30(3):487-501. Murto C, Ariza L, Alencar CH, Chichava OA, Oliveira AR, Kaplan C, Silva LF, Heukelbach J. PMID: 24714939.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    18. Injecting transition risk and depression among Mexican American non-injecting heroin users. Drug Alcohol Depend. 2012 Sep; 125 Suppl 1:S12-7. Cepeda A, Kaplan C, Neaigus A, Cano MÁ, Villarreal Y, Valdez A. PMID: 22749681.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    19. Relationship of fruit, vegetable, and fat consumption to binge eating symptoms in African American and Hispanic or Latina women. Eat Behav. 2012 Apr; 13(2):179-82. Wilson PL, O'Connor DP, Kaplan CD, Bode S, Mama SK, Lee RE. PMID: 22365808.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    20. Health consequences of long-term injection heroin use among aging Mexican American men. J Aging Health. 2011 Sep; 23(6):912-32. Torres LR, Kaplan C, Valdez A. PMID: 21451118.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    21. High rates of transitions to injecting drug use among Mexican American non-injecting heroin users in San Antonio, Texas (never and former injectors). Drug Alcohol Depend. 2011 Apr 01; 114(2-3):233-6. Valdez A, Neaigus A, Kaplan C, Cepeda A. PMID: 21075561.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    22. Regulation of cytokine secretion in human CD127(+) LTi-like innate lymphoid cells by Toll-like receptor 2. Immunity. 2010 Nov 24; 33(5):752-64. Crellin NK, Trifari S, Kaplan CD, Satoh-Takayama N, Di Santo JP, Spits H. PMID: 21055975.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    23. Fumando la piedra: emerging patterns of crack use among Latino immigrant day laborers in New Orleans. J Immigr Minor Health. 2010 Oct; 12(5):737-42. Valdez A, Cepeda A, Negi NJ, Kaplan C. PMID: 19924538.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    24. Delinquency in context; neighbourhood and gender interactions among adolescents. Epidemiol Psichiatr Soc. 2010 Apr-Jun; 19(2):148-58. Drukker M, Kaplan CD, Feron FJ, Van Os J, Korebrits A. PMID: 20815299.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    25. Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells. J Exp Med. 2010 Feb 15; 207(2):281-90. Crellin NK, Trifari S, Kaplan CD, Cupedo T, Spits H. PMID: 20142432.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansCells
    26. The association between disaster-related experiences and mental health outcomes among drug using African American Hurricane Katrina evacuees. Community Ment Health J. 2010 Dec; 46(6):612-20. Cepeda A, Saint Onge JM, Kaplan C, Valdez A. PMID: 20091228.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    27. Patterns of substance use among hurricane Katrina evacuees in Houston, Texas. Disasters. 2010 Apr; 34(2):426-46. Cepeda A, Valdez A, Kaplan C, Hill LE. PMID: 19863564.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    28. Homicidal Events Among Mexican American Street Gangs: A Situational Analysis. Homicide Stud. 2009 Sep 01; 13(3):288-306. Valdez A, Cepeda A, Kaplan C. PMID: 21218188.
      View in: PubMed   Mentions:
    29. Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat Immunol. 2009 Aug; 10(8):864-71. Trifari S, Kaplan CD, Tran EH, Crellin NK, Spits H. PMID: 19578368.
      View in: PubMed   Mentions: 306     Fields:    Translation:HumansCells
    30. The Influence of Family and Peer Risk Networks on Drug Use Practices and Other Risks among Mexican American Noninjecting Heroin Users. J Contemp Ethnogr. 2008 Feb 01; 37(1):79-107. Valdez A, Neaigus A, Kaplan CD. PMID: 19337564.
      View in: PubMed   Mentions:
    31. The ibogaine medical subculture. J Ethnopharmacol. 2008 Jan 04; 115(1):9-24. Alper KR, Lotsof HS, Kaplan CD. PMID: 18029124.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    32. DNA vaccination against VEGF receptor 2 reduces atherosclerosis in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol. 2007 May; 27(5):1095-100. Petrovan RJ, Kaplan CD, Reisfeld RA, Curtiss LK. PMID: 17303776.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCellsPHPublic Health
    33. Aggressive crime, alcohol and drug use, and concentrated poverty in 24 U.S. urban areas. Am J Drug Alcohol Abuse. 2007; 33(4):595-603. Valdez A, Kaplan CD, Curtis RL. PMID: 17668345.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
      View in: PubMed   Mentions:
    35. Characterization of stem cell-like cancer cells in immune-competent mice. Blood. 2006 Dec 01; 108(12):3906-12. Kruger JA, Kaplan CD, Luo Y, Zhou H, Markowitz D, Xiang R, Reisfeld RA. PMID: 16912222.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    36. Targeting tumor-associated macrophages as a novel strategy against breast cancer. J Clin Invest. 2006 Aug; 116(8):2132-2141. Luo Y, Zhou H, Krueger J, Kaplan C, Lee SH, Dolman C, Markowitz D, Wu W, Liu C, Reisfeld RA, Xiang R. PMID: 16862213.
      View in: PubMed   Mentions: 195     Fields:    Translation:AnimalsCells
    37. A novel DNA vaccine encoding PDGFRbeta suppresses growth and dissemination of murine colon, lung and breast carcinoma. Vaccine. 2006 Nov 17; 24(47-48):6994-7002. Kaplan CD, Krüger JA, Zhou H, Luo Y, Xiang R, Reisfeld RA. PMID: 17050049.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCellsPHPublic Health
    38. The drugs-violence nexus among Mexican-American gang members. J Psychoactive Drugs. 2006 Jun; 38(2):109-21. Valdez A, Kaplan CD, Cepeda A. PMID: 16903450.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    39. The wider social environment and changes in self-reported quality of life in the transition from late childhood to early adolescence: a cohort study. BMC Public Health. 2006 May 17; 6:133. Drukker M, Kaplan C, Schneiders J, Feron FJ, van Os J. PMID: 16707015.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    40. Endoglin (CD105) is a target for an oral DNA vaccine against breast cancer. Cancer Immunol Immunother. 2006 Dec; 55(12):1565-74. Lee SH, Mizutani N, Mizutani M, Luo Y, Zhou H, Kaplan C, Kim SW, Xiang R, Reisfeld RA. PMID: 16565828.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    41. Measuring violence risk and outcomes among Mexican American adolescent females. J Interpers Violence. 2006 Jan; 21(1):24-41. Cervantes RC, Duenas N, Valdez A, Kaplan C. PMID: 16399922.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    42. On cannabis, chloral hydrate, and career cycles of psychotropic drugs in medicine. Bull Hist Med. 2006; 80(1):95-114. Snelders S, Kaplan C, Pieters T. PMID: 16549883.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    43. A DNA-based cancer vaccine enhances lymphocyte cross talk by engaging the NKG2D receptor. Blood. 2006 Apr 15; 107(8):3251-7. Zhou H, Luo Y, Kaplan CD, Krüger JA, Lee SH, Xiang R, Reisfeld RA. PMID: 16368879.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    44. DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the NKG2D receptor. Proc Natl Acad Sci U S A. 2005 Aug 02; 102(31):10846-51. Zhou H, Luo Y, Lo JF, Kaplan CD, Mizutani M, Mizutani N, Lee JD, Primus FJ, Becker JC, Xiang R, Reisfeld RA. PMID: 16040807.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    45. Residential instability in socioeconomically deprived neighbourhoods, good or bad? Health Place. 2005 Jun; 11(2):121-9. Drukker M, Kaplan C, van Os J. PMID: 15629680.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    46. Development of proteoglycan-induced arthritis is critically dependent on Fcgamma receptor type III expression. Arthritis Rheum. 2005 May; 52(5):1612-9. Kaplan CD, Cao Y, Verbeek JS, Tunyogi-Csapo M, Finnegan A. PMID: 15880819.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    47. Social capital and young adolescents' perceived health in different sociocultural settings. Soc Sci Med. 2005 Jul; 61(1):185-98. Drukker M, Buka SL, Kaplan C, McKenzie K, Van Os J. PMID: 15847971.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    48. Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people. BMJ. 2005 Jan 01; 330(7481):11. Henquet C, Krabbendam L, Spauwen J, Kaplan C, Lieb R, Wittchen HU, van Os J. PMID: 15574485.
      View in: PubMed   Mentions: 132     Fields:    Translation:Humans
    49. Problem severity profiles of substance abusing women in European Therapeutic Communities: influence of psychiatric problems. J Subst Abuse Treat. 2004 Jun; 26(4):243-51. De Wilde J, Soyez V, Broekaert E, Rosseel Y, Kaplan C, Larsson J. PMID: 15182888.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    50. Temperament characteristics of street and non-street children in Eldoret, Kenya. Afr Health Sci. 2004 Apr; 4(1):24-30. Ayuku DO, Devries MW, Mengech HN, Kaplan CD. PMID: 15126189.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    51. Children's health-related quality of life, neighbourhood socio-economic deprivation and social capital. A contextual analysis. Soc Sci Med. 2003 Sep; 57(5):825-41. Drukker M, Kaplan C, Feron F, van Os J. PMID: 12850109.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    52. Osteoclasts, pro-inflammatory cytokines, RANK-L and bone remodeling in rheumatoid arthritis. Front Biosci. 2003 May 01; 8:d1018-29. Kaplan C, Finnegan A. PMID: 12700082.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    53. Social network analysis for health and social interventions among Kenyan scavenging street children. Health Policy Plan. 2003 Mar; 18(1):109-18. Ayuku D, Odero W, Kaplan C, De Bruyn R, De Vries M. PMID: 12582114.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    54. Development of inflammation in proteoglycan-induced arthritis is dependent on Fc gamma R regulation of the cytokine/chemokine environment. J Immunol. 2002 Nov 15; 169(10):5851-9. Kaplan CD, O'Neill SK, Koreny T, Czipri M, Finnegan A. PMID: 12421967.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    55. Collagen-induced arthritis is exacerbated in IL-10-deficient mice. Arthritis Res Ther. 2003; 5(1):R18-24. Finnegan A, Kaplan CD, Cao Y, Eibel H, Glant TT, Zhang J. PMID: 12716449.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    56. IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms. J Immunol. 2002 Sep 15; 169(6):3345-52. Finnegan A, Grusby MJ, Kaplan CD, O'Neill SK, Eibel H, Koreny T, Czipri M, Mikecz K, Zhang J. PMID: 12218156.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    57. LSD therapy in Dutch psychiatry: changing socio-political settings and medical sets. Med Hist. 2002 Apr; 46(2):221-40. Snelders S, Kaplan C. PMID: 12024809.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    58. Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis. Arthritis Res. 2002; 4(1):54-8. Kaplan C, Valdez JC, Chandrasekaran R, Eibel H, Mikecz K, Glant TT, Finnegan A. PMID: 11879537.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    59. Psychopathy Among Mexican American Gang Members: A Comparative Study. Int J Offender Ther Comp Criminol. 2000 Feb; 44(1):46-58. Valdez A, Kaplan CD, Codina E. PMID: 21516257.
      View in: PubMed   Mentions: 3     Fields:    
    60. The process of paradoxical autonomy and survival in the heroin careers of Mexican American women. Contemp Drug Probl. 2000; 27:189. Valdez A, Kaplan CD, Cepeda A. PMID: 21057594.
      View in: PubMed   Mentions:
    61. The prospects and limitations of compulsory treatment for drug addiction. J Drug Issues. 1988; 18(4):505-25. Platt JJ, Buhringer G, Kaplan CD, Brown BS, Taube DO. PMID: 11650856.
      View in: PubMed   Mentions:
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