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Burcu Darst

Title(s)Postdoctoral Scholar - Research Associate
Address1450 Biggy Street
Health Sciences Campus
Los Angeles CA 90033
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    Collapse Biography 
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    University of Wisconsin, MadisonPhD08/2018Genetic Epidemiology

    Collapse Research 
    Collapse Research Activities and Funding
    Integrating Genomics and Metabolomics to Develop Predictive Models of Prostate Cancer in Multiethnic Men
    NIH K99CA246063Feb 1, 2020 - Jan 31, 2022
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry. Eur Urol. 2020 May 12. Darst BF, Wan P, Sheng X, Bensen JT, Ingles SA, Rybicki BA, Nemesure B, John EM, Fowke JH, Stevens VL, Berndt SI, Huff CD, Strom SS, Park JY, Zheng W, Ostrander EA, Walsh PC, Srivastava S, Carpten J, Sellers TA, Yamoah K, Murphy AB, Sanderson M, Crawford DC, Gapstur SM, Bush WS, Aldrich MC, Cussenot O, Yeager M, Petrovics G, Cullen J, Neslund-Dudas C, Kittles RA, Xu J, Stern MC, Kote-Jarai Z, Govindasami K, Chokkalingam AP, Multigner L, Parent ME, Menegaux F, Cancel-Tassin G, Kibel AS, Klein EA, Goodman PJ, Drake BF, Hu JJ, Clark PE, Blanchet P, Casey G, Hennis AJM, Lubwama A, Thompson IM, Leach R, Gundell SM, Pooler L, Xia L, Mohler JL, Fontham ETH, Smith GJ, Taylor JA, Eeles RA, Brureau L, Chanock SJ, Watya S, Stanford JL, Mandal D, Isaacs WB, Cooney K, Blot WJ, Conti DV, Haiman CA. PMID: 32409115.
      View in: PubMed   Mentions: 1     Fields:    
    2. The Four-Kallikrein Panel Is Effective in Identifying Aggressive Prostate Cancer in a Multiethnic Population. Cancer Epidemiol Biomarkers Prev. 2020 Jul; 29(7):1381-1388. Darst BF, Chou A, Wan P, Pooler L, Sheng X, Vertosick EA, Conti DV, Wilkens LR, Le Marchand L, Vickers AJ, Lilja HG, Haiman CA. PMID: 32385116.
      View in: PubMed   Mentions:    Fields:    
    3. Integrated analysis of genomics, longitudinal metabolomics, and Alzheimer's risk factors among 1,111 cohort participants. Genet Epidemiol. 2019 09; 43(6):657-674. Darst BF, Lu Q, Johnson SC, Engelman CD. PMID: 31104335.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    4. KLOTHO heterozygosity attenuates APOE4-related amyloid burden in preclinical AD. Neurology. 2019 Apr 16; 92(16):e1878-e1889. Erickson CM, Schultz SA, Oh JM, Darst BF, Ma Y, Norton D, Betthauser T, Gallagher CL, Carlsson CM, Bendlin BB, Asthana S, Hermann BP, Sager MA, Blennow K, Zetterberg H, Engelman CD, Christian BT, Johnson SC, Dubal DB, Okonkwo OC. PMID: 30867273.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    5. Carrier frequency estimation of Zellweger spectrum disorder using ExAC database and bioinformatics tools. Genet Med. 2019 09; 21(9):1969-1976. Vasiljevic E, Ye Z, Pavelec DM, Darst BF, Engelman CD, Baker MW. PMID: 30846882.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    6. Longitudinal plasma metabolomics of aging and sex. Aging (Albany NY). 2019 02 24; 11(4):1262-1282. Darst BF, Koscik RL, Hogan KJ, Johnson SC, Engelman CD. PMID: 30799310.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    7. The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer's disease. Alzheimers Res Ther. 2018 12 22; 10(1):124. Vogt NM, Romano KA, Darst BF, Engelman CD, Johnson SC, Carlsson CM, Asthana S, Blennow K, Zetterberg H, Bendlin BB, Rey FE. PMID: 30579367.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    8. Using recursive feature elimination in random forest to account for correlated variables in high dimensional data. BMC Genet. 2018 09 17; 19(Suppl 1):65. Darst BF, Malecki KC, Engelman CD. PMID: 30255764.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. Data mining and machine learning approaches for the integration of genome-wide association and methylation data: methodology and main conclusions from GAW20. BMC Genet. 2018 09 17; 19(Suppl 1):76. Darst B, Engelman CD, Tian Y, Lorenzo Bermejo J. PMID: 30255774.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. The effect of rare variants in TREM2 and PLD3 on longitudinal cognitive function in the Wisconsin Registry for Alzheimer's Prevention. Neurobiol Aging. 2018 06; 66:177.e1-177.e5. Engelman CD, Darst BF, Bilgel M, Vasiljevic E, Koscik RL, Jedynak BM, Johnson SC. PMID: 29395285.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. BDNF Val66Met predicts cognitive decline in the Wisconsin Registry for Alzheimer's Prevention. Neurology. 2017 May 30; 88(22):2098-2106. Boots EA, Schultz SA, Clark LR, Racine AM, Darst BF, Koscik RL, Carlsson CM, Gallagher CL, Hogan KJ, Bendlin BB, Asthana S, Sager MA, Hermann BP, Christian BT, Dubal DB, Engelman CD, Johnson SC, Okonkwo OC. PMID: 28468845.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    12. Cardiorespiratory fitness alters the influence of a polygenic risk score on biomarkers of AD. Neurology. 2017 Apr 25; 88(17):1650-1658. Schultz SA, Boots EA, Darst BF, Zetterberg H, Blennow K, Edwards DF, Koscik RL, Carlsson CM, Gallagher CL, Bendlin BB, Asthana S, Sager MA, Hogan KJ, Hermann BP, Cook DB, Johnson SC, Engelman CD, Okonkwo OC. PMID: 28341646.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    13. Macrovascular and microvascular cerebral blood flow in adults at risk for Alzheimer's disease. Alzheimers Dement (Amst). 2017; 7:48-55. Clark LR, Berman SE, Rivera-Rivera LA, Hoscheidt SM, Darst BF, Engelman CD, Rowley HA, Carlsson CM, Asthana S, Turski P, Wieben O, Johnson SC. PMID: 28239641.
      View in: PubMed   Mentions:
    14. Pathway-Specific Polygenic Risk Scores as Predictors of Amyloid-ß Deposition and Cognitive Function in a Sample at Increased Risk for Alzheimer's Disease. J Alzheimers Dis. 2017; 55(2):473-484. Darst BF, Koscik RL, Racine AM, Oh JM, Krause RA, Carlsson CM, Zetterberg H, Blennow K, Christian BT, Bendlin BB, Okonkwo OC, Hogan KJ, Hermann BP, Sager MA, Asthana S, Johnson SC, Engelman CD. PMID: 27662287.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    15. Patient perspectives on whole-genome sequencing for undiagnosed diseases. Per Med. 2017 01; 14(1):17-25. Boeldt DL, Cheung C, Ariniello L, Darst BF, Topol S, Schork NJ, Philis-Tsimikas A, Torkamani A, Fortmann AL, Bloss CS. PMID: 29749824.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Transmission and decorrelation methods for detecting rare variants using sequencing data from related individuals. BMC Proc. 2016; 10(Suppl 7):203-207. Darst BF, Engelman CD. PMID: 27980637.
      View in: PubMed   Mentions:
    17. Prioritization of family member sequencing for the detection of rare variants. BMC Proc. 2016; 10(Suppl 7):227-231. Sippy R, Kolesar JM, Darst BF, Engelman CD. PMID: 27980641.
      View in: PubMed   Mentions:
    18. Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children. Brain Imaging Behav. 2016 Mar; 10(1):272-82. Eicher JD, Montgomery AM, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork NJ, Darst BF, Casey BJ, Chang L, Ernst T, Frazier J, Kaufmann WE, Keating B, Kenet T, Kennedy D, Mostofsky S, Murray SS, Sowell ER, Bartsch H, Kuperman JM, Brown TT, Hagler DJ, Dale AM, Jernigan TL, Gruen JR. PMID: 25953057.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    19. A genome sequencing program for novel undiagnosed diseases. Genet Med. 2015 Dec; 17(12):995-1001. Bloss CS, Zeeland AA, Topol SE, Darst BF, Boeldt DL, Erikson GA, Bethel KJ, Bjork RL, Friedman JR, Hwynn N, Patay BA, Pockros PJ, Scott ER, Simon RA, Williams GW, Schork NJ, Topol EJ, Torkamani A. PMID: 25790160.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    20. Heritability of cognitive traits among siblings with a parental history of Alzheimer's disease. J Alzheimers Dis. 2015; 45(4):1149-55. Darst BF, Koscik RL, Hermann BP, La Rue A, Sager MA, Johnson SC, Engelman CD. PMID: 25649654.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Candidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults. Am J Geriatr Psychiatry. 2014 Oct; 22(10):997-1006.e5. Rana BK, Darst BF, Bloss C, Shih PA, Depp C, Nievergelt CM, Allison M, Parsons JK, Schork N, Jeste DV. PMID: 24791650.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    22. Impact of direct-to-consumer genomic testing at long term follow-up. J Med Genet. 2013 Jun; 50(6):393-400. Bloss CS, Wineinger NE, Darst BF, Schork NJ, Topol EJ. PMID: 23559530.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    23. Characteristics of genomic test consumers who spontaneously share results with their health care provider. Health Commun. 2014; 29(1):105-8. Darst BF, Madlensky L, Schork NJ, Topol EJ, Bloss CS. PMID: 23384116.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    24. Long-term influence of normal variation in neonatal characteristics on human brain development. Proc Natl Acad Sci U S A. 2012 Dec 04; 109(49):20089-94. Walhovd KB, Fjell AM, Brown TT, Kuperman JM, Chung Y, Hagler DJ, Roddey JC, Erhart M, McCabe C, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork NJ, Darst BF, Casey BJ, Chang L, Ernst TM, Frazier J, Gruen JR, Kaufmann WE, Murray SS, van Zijl P, Mostofsky S, Dale AM. PMID: 23169628.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    25. Multimodal imaging of the self-regulating developing brain. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19620-5. Fjell AM, Walhovd KB, Brown TT, Kuperman JM, Chung Y, Hagler DJ, Venkatraman V, Roddey JC, Erhart M, McCabe C, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Darst BF, Schork NJ, Casey BJ, Chang L, Ernst TM, Gruen JR, Kaufmann WE, Kenet T, Frazier J, Murray SS, Sowell ER, van Zijl P, Mostofsky S, Jernigan TL, Dale AM. PMID: 23150548.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    26. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3985-90. Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM, Weiner M, Aisen P, Petersen R, Jack CR, Jagust W, Trojanowki JQ, Toga AW, Beckett L, Green RC, Saykin AJ, Morris J, Liu E, Montine T, Gamst A, Thomas RG, Donohue M, Walter S, Gessert D, Sather T, Harvey D, Kornak J, Dale A, Bernstein M, Felmlee J, Fox N, Thompson P, Schuff N, Alexander G, DeCarli C, Bandy D, Koeppe RA, Foster N, Reiman EM, Chen K, Mathis C, Cairns NJ, Taylor-Reinwald L, Trojanowki JQ, Shaw L, Lee VM, Korecka M, Crawford K, Neu S, Foroud TM, Potkin S, Shen L, Kachaturian Z, Frank R, Snyder PJ, Molchan S, Kaye J, Quinn J, Lind B, Dolen S, Schneider LS, Pawluczyk S, Spann BM, Brewer J, Vanderswag H, Heidebrink JL, Lord JL, Johnson K, Doody RS, Villanueva-Meyer J, Chowdhury M, Stern Y, Honig LS, Bell KL, Morris JC, Ances B, Carroll M, Leon S, Mintun MA, Schneider S, Marson D, Griffith R, Clark D, Grossman H, Mitsis E, Romirowsky A, deToledo-Morrell L, Shah RC, Duara R, Varon D, Roberts P, Albert M, Onyike C, Kielb S, Rusinek H, de Leon MJ, Glodzik L, De Santi S, Doraiswamy PM, Petrella JR, Coleman RE, Arnold SE, Karlawish JH, Wolk D, Smith CD, Jicha G, Hardy P, Lopez OL, Oakley M, Simpson DM, Porsteinsson AP, Goldstein BS, Martin K, Makino KM, Ismail MS, Brand C, Mulnard RA, Thai G, Mc-Adams-Ortiz C, Womack K, Mathews D, Quiceno M, Diaz-Arrastia R, King R, Weiner M, Martin-Cook K, DeVous M, Levey AI, Lah JJ, Cellar JS, Burns JM, Anderson HS, Swerdlow RH, Apostolova L, Lu PH, Bartzokis G, Silverman DH, Graff-Radford NR, Parfitt F, Johnson H, Farlow MR, Hake AM, Matthews BR, Herring S, van Dyck CH, Carson RE, MacAvoy MG, Chertkow H, Bergman H, Hosein C, Black S, Stefanovic B, Caldwell C, Hsiung R, Feldman H, Mudge B, Assaly M, Kertesz A, Rogers J, Trost D, Bernick C, Munic D, Kerwin D, Mesulam MM, Lipowski K, Wu CK, Johnson N, Sadowsky C, Martinez W, Villena T, Turner RS, Johnson K, Reynolds B, Sperling RA, Johnson KA, Marshall G, Frey M, Yesavage J, Taylor JL, Lane B, Rosen A, Tinklenberg J, Sabbagh M, Belden C, Jacobson S, Kowall N, Killiany R, Budson AE, Norbash A, Johnson PL, Obisesan TO, Wolday S, Bwayo SK, Lerner A, Hudson L, Ogrocki P, Fletcher E, Carmichael O, Olichney J, Kittur S, Borrie M, Lee TY, Bartha R, Johnson S, Asthana S, Carlsson CM, Potkin SG, Preda A, Nguyen D, Tariot P, Fleisher A, Reeder S, Bates V, Capote H, Rainka M, Scharre DW, Kataki M, Zimmerman EA, Celmins D, Brown AD, Pearlson GD, Blank K, Anderson K, Santulli RB, Schwartz ES, Sink KM, Williamson JD, Garg P, Watkins F, Ott BR, Querfurth H, Tremont G, Salloway S, Malloy P, Correia S, Rosen HJ, Miller BL, Mintzer J, Longmire CF, Spicer K, Finger E, Rachinsky I, Drost D, Jernigan T, McCabe C, Grant E, Ernst T, Kuperman J, Chung Y, Murray S, Bloss C, Darst B, Pritchett L, Saito A, Amaral D, DiNino M, Eyngorina B, Sowell E, Houston S, Soderberg L, Kaufmann W, van Zijl P, Rizzo-Busack H, Javid M, Mehta N, Ruberry E, Powers A, Rosen B, Gebhard N, Manigan H, Frazier J, Kennedy D, Yakutis L, Hill M, Gruen J, Bosson-Heenan J, Carlson H. PMID: 22343285.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    27. Direct-to-consumer personalized genomic testing. Hum Mol Genet. 2011 Oct 15; 20(R2):R132-41. Bloss CS, Darst BF, Topol EJ, Schork NJ. PMID: 21828075.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
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