Andrew P. McMahon, PhD

Title(s)W.M. Keck Provost and University Professor of Stem Cell Biology and Regenerative Medicine, Biological Sciences and Quantitative and Computational Biology
SchoolKeck School of Medicine of Usc
AddressBCC 312 1425 San Pablo Street
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 442 3056
vCardDownload vCard
    Other Positions
    Title(s)Chair of Stem Cell Biology and Regenerative Medicine

    Title(s)Director, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC


    Collapse Overview 
    Collapse Overview
    Professor Andrew (Andy) McMahon is the Chair of the Department of Stem Cell Biology and Regenerative Medicine and Director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at the Keck School of Medicine of the University of Southern California (USC). McMahon joined USC from Harvard University in 2012 as the W.M. Keck Provost Professor of Stem Cell Biology and Regenerative Medicine, and Biological Sciences, and founding chair of the Department of Stem Cell Biology and Regenerative Medicine.

    McMahon is a leader in the field of developmental biology. McMahon’s research has provided fundamental insights into the cell interactions driving assembly of multiple organ systems, including the central nervous system, skeleton and kidney. McMahon’s research has identified diverse mechanisms regulating organ development, tissue repair and cancer. Current research focuses on development, injury and repair of the mammalian kidney, to model and treat kidney disease.

    McMahon received his bachelor's degree from Oxford University and his PhD from University College London. McMahon completed his postdoctoral research at the California Institute of Technology, then moved to London to start his independent research laboratory in 1984. In 1988, McMahon took up a position as assistant member at the Roche Institute for Molecular Biology, becoming full member and chair of the department in 1992. In 1993, McMahon became a professor of Molecular and Cellular Biology in the Faculty of Arts and Sciences at Harvard University. In a 19-year career at Harvard, McMahon was the Frank B. Baird Jr., Professor of Science, chair of the Department of Cell and Developmental Biology, a founding faculty of the Department of Stem Cells and Regenerative Biology, and principal investigator of the Harvard Stem Cell Institute.

    McMahon is an elected fellow of the National Academy of Sciences, the American Association for the Advancement of Science, the American Academy of Arts and Sciences, the European Molecular Biology Organization and the Royal Society.

    Collapse Research 
    Collapse Research Activities and Funding
    Sexual dimorphism in the mammalian kidney
    NIH R01DK126925Sep 17, 2020 - May 31, 2025
    Role: Principal Investigator
    Single-cell analysis to promote kidney repair
    NIH UC2DK126024Sep 1, 2020 - May 31, 2025
    Role: Co-Principal Investigator
    Mapping protein communication between organs in homeostasis and disease
    NIH R01DK121409Sep 25, 2018 - Jun 30, 2023
    Role: Co-Principal Investigator
    Epigenetic mechanisms underlying the failure of hair cell regeneration in mammals
    NIH R01DC015829Jul 1, 2018 - Jun 30, 2023
    Role: Co-Principal Investigator
    Establishing Mechanisms of Human Proximal Tubule Regeneration in an Engineered Organ on Chip Platform
    NIH R21EB025534Sep 23, 2017 - Jul 31, 2021
    Role: Co-Principal Investigator
    Four-dimensional Modeling of Mouse and Human Nephrogenesis.
    NIH U01DK110792Sep 15, 2016 - May 31, 2021
    Role: Principal Investigator
    Lineage reprogramming for hearing loss: development of drug screening and gene therapy approaches
    NIH R01DC015530Jul 1, 2016 - Jun 30, 2021
    Role: Co-Principal Investigator
    The USC (Re)Building the Kidney Coordinating Center
    NIH U01DK107350Sep 23, 2015 - Aug 31, 2021
    Role: Co-Principal Investigator
    GUDMAP2 - Production of Mouse Strains for Gene Anatomy of the Lower Urinary Tract
    NIH U01DK094526Sep 30, 2011 - Mar 31, 2017
    Role: Principal Investigator
    Kidney molecular atlas project
    NIH U01DK070181Sep 30, 2004 - Jul 31, 2012
    Role: Principal Investigator
    Developmental Regulation of Bone Morphogenesis
    NIH P01DK056246Aug 20, 1999 - May 31, 2016
    Role: Co-Principal Investigator
    Cell Interactions in Development of the Mammalian Kidney
    NIH R01DK054364Sep 1, 1998 - Dec 31, 2022
    Role: Principal Investigator
    Cell Interactions in Development of the Mammalian Kidney
    NIH R37DK054364Sep 1, 1998 - Jan 14, 2019
    Role: Principal Investigator
    CONFERENCE ON VERTEBRATE DEVELOPMENT
    NIH R13HD036196Mar 1, 1998 - Feb 28, 1999
    Role: Principal Investigator
    Regulation of polarity by Sonic hedgehog morphogen signaling
    NIH R01NS033642Dec 1, 1994 - Jul 31, 2018
    Role: Principal Investigator
    Regulation of CNS and Limb Polarity by Sonic Hedgehog
    NIH R37NS033642Dec 1, 1994 - Sep 14, 2012
    Role: Principal Investigator
    ACTIVATION OF A PATTERNING SIGNAL IN THE CNS
    NIH R01NS032691Apr 1, 1994 - Mar 31, 1998
    Role: Principal Investigator
    PATTERN REGULATION IN THE VERTEBRATE CNS
    NIH R01HD030249Dec 1, 1993 - Nov 30, 2003
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Faculty Mentoring
    Collapse Required Scholarly Project Mentor

    Collapse Featured Content 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Spatial transcriptomics defines injury-specific microenvironments in the adult mouse kidney and novel cellular interactions in regeneration and disease. bioRxiv. 2023 Nov 22. Polonsky M, Gerhardt LMS, Yun J, Koppitch K, Colón KL, Amrhein H, Zheng S, Yuan GC, Thomson M, Cai L, McMahon AP. PMID: 38045285; PMCID: PMC10690238.
      View in: PubMed   Mentions:
    2. Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney. Dev Cell. 2023 11 06; 58(21):2338-2358.e5. Xiong L, Liu J, Han SY, Koppitch K, Guo JJ, Rommelfanger M, Miao Z, Gao F, Hallgrimsdottir IB, Pachter L, Kim J, MacLean AL, McMahon AP. PMID: 37673062; PMCID: PMC10873092.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    3. Canonical Wnt transcriptional complexes are essential for induction of nephrogenesis but not maintenance or proliferation of nephron progenitors. bioRxiv. 2023 Aug 21. Bugacov H, Der B, Kim S, Lindström NO, McMahon AP. PMID: 37662369; PMCID: PMC10473675.
      View in: PubMed   Mentions:
    4. User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium. APL Bioeng. 2023 Sep; 7(3):036106. Khalil NN, Petersen AP, Song CJ, Chen Y, Takamoto K, Kellogg AC, Chen EZ, McMahon AP, McCain ML. PMID: 37584027; PMCID: PMC10424157.
      View in: PubMed   Mentions: 1  
    5. Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids. bioRxiv. 2023 May 25. Huang B, Zeng Z, Li H, Li Z, Chen X, Guo J, Zhang CC, Schreiber ME, Vonk AC, Xiang T, Patel T, Li Y, Parvez RK, Der B, Chen JH, Liu Z, Thornton ME, Grubbs BH, Diao Y, Dou Y, Gnedeva K, Lindström NO, Ying Q, Pastor-Soler NM, Fei T, Hallows KR, McMahon AP, Li Z. PMID: 37293038; PMCID: PMC10245960.
      View in: PubMed   Mentions:
    6. Direct androgen receptor regulation of sexually dimorphic gene expression in the mammalian kidney. bioRxiv. 2023 May 25. Xiong L, Liu J, Han SY, Koppitch K, Guo JJ, Rommelfanger M, Gao F, Hallgrimsdottir IB, Pachter L, Kim J, MacLean AL, McMahon AP. PMID: 37205355; PMCID: PMC10187285.
      View in: PubMed   Mentions:
    7. Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development. bioRxiv. 2023 May 17. Kim S, Koppitch K, Parvez RK, Guo J, Achieng M, Schnell J, Lindström NO, McMahon AP. PMID: 37293066; PMCID: PMC10245679.
      View in: PubMed   Mentions:
    8. Proximal tubule responses to injury: interrogation by single-cell transcriptomics. Curr Opin Nephrol Hypertens. 2023 07 01; 32(4):352-358. Cippà PE, McMahon AP. PMID: 37074682; PMCID: PMC10330172.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Lineage Tracing and Single-Nucleus Multiomics Reveal Novel Features of Adaptive and Maladaptive Repair after Acute Kidney Injury. J Am Soc Nephrol. 2023 04 01; 34(4):554-571. Gerhardt LMS, Koppitch K, van Gestel J, Guo J, Cho S, Wu H, Kirita Y, Humphreys BD, McMahon AP. PMID: 36735940; PMCID: PMC10103206.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    10. Identifying Common Molecular Mechanisms in Experimental and Human Acute Kidney Injury. Semin Nephrol. 2022 05; 42(3):151286. Gerhardt LMS, McMahon AP. PMID: 36402654.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    11. Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages. Cell Rep. 2022 09 06; 40(10):111315. Hojo H, Saito T, He X, Guo Q, Onodera S, Azuma T, Koebis M, Nakao K, Aiba A, Seki M, Suzuki Y, Okada H, Tanaka S, Chung UI, McMahon AP, Ohba S. PMID: 36070691; PMCID: PMC9510047.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    12. A genetic model for in vivo proximity labelling of the mammalian secretome. Open Biol. 2022 08; 12(8):220149. Yang R, Meyer AS, Droujinine IA, Udeshi ND, Hu Y, Guo J, McMahon JA, Carey DK, Xu C, Fang Q, Sha J, Qin S, Rocco D, Wohlschlegel J, Ting AY, Carr SA, Perrimon N, McMahon AP. PMID: 35946312; PMCID: PMC9364151.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    13. A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery. Cell Stem Cell. 2022 07 07; 29(7):1083-1101.e7. Tran T, Song CJ, Nguyen T, Cheng SY, McMahon JA, Yang R, Guo Q, Der B, Lindström NO, Lin DC, McMahon AP. PMID: 35803227.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    14. Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing. Proc Natl Acad Sci U S A. 2022 06 21; 119(25):e2203179119. Xu J, Liu Y, Li H, Tarashansky AJ, Kalicki CH, Hung RJ, Hu Y, Comjean A, Kolluru SS, Wang B, Quake SR, Luo L, McMahon AP, Dow JAT, Perrimon N. PMID: 35696569; PMCID: PMC9231607.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    15. Kidney repair and regeneration: perspectives of the NIDDK (Re)Building a Kidney consortium. Kidney Int. 2022 05; 101(5):845-853. Naved BA, Bonventre JV, Hubbell JA, Hukriede NA, Humphreys BD, Kesselman C, Valerius MT, McMahon AP, Shankland SJ, Wertheim JA, White MJV, de Caestecker MP, Drummond IA. PMID: 35276204; PMCID: PMC9045003.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    16. Repairing the blood-brain barrier. Science. 2022 02 18; 375(6582):715-716. McMahon AP, Ichida JK. PMID: 35175806.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    17. Multi-omic approaches to acute kidney injury and repair. Curr Opin Biomed Eng. 2021 Dec; 20. Gerhardt LMS, McMahon AP. PMID: 35005326; PMCID: PMC8740908.
      View in: PubMed   Mentions: 5  
    18. Spatial transcriptional mapping of the human nephrogenic program. Dev Cell. 2021 08 23; 56(16):2381-2398.e6. Lindström NO, Sealfon R, Chen X, Parvez RK, Ransick A, De Sena Brandine G, Guo J, Hill B, Tran T, Kim AD, Zhou J, Tadych A, Watters A, Wong A, Lovero E, Grubbs BH, Thornton ME, McMahon JA, Smith AD, Ruffins SW, Armit C, Troyanskaya OG, McMahon AP. PMID: 34428401; PMCID: PMC8396064.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    19. Multi-omics integration in the age of million single-cell data. Nat Rev Nephrol. 2021 11; 17(11):710-724. Miao Z, Humphreys BD, McMahon AP, Kim J. PMID: 34417589; PMCID: PMC9191639.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    20. Single-nuclear transcriptomics reveals diversity of proximal tubule cell states in a dynamic response to acute kidney injury. Proc Natl Acad Sci U S A. 2021 07 06; 118(27). Gerhardt LMS, Liu J, Koppitch K, Cippà PE, McMahon AP. PMID: 34183416; PMCID: PMC8271768.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    21. Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors. Nat Commun. 2021 06 15; 12(1):3641. Zeng Z, Huang B, Parvez RK, Li Y, Chen J, Vonk AC, Thornton ME, Patel T, Rutledge EA, Kim AD, Yu J, Grubbs BH, McMahon JA, Pastor-Soler NM, Hallows KR, McMahon AP, Li Z. PMID: 34131121; PMCID: PMC8206157.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    22. Correction: A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells. Elife. 2021 Apr 29; 10. Guo Q, Kim AD, Li B, Ransick A, Bugacov H, Chen X, Lindström NO, Brown A, Oxburgh L, Ren B, McMahon AP. PMID: 33913807; PMCID: PMC8084526.
      View in: PubMed   Mentions:    Fields:    
    23. Proteomics of protein trafficking by in vivo tissue-specific labeling. Nat Commun. 2021 04 22; 12(1):2382. Droujinine IA, Meyer AS, Wang D, Udeshi ND, Hu Y, Rocco D, McMahon JA, Yang R, Guo J, Mu L, Carey DK, Svinkina T, Zeng R, Branon T, Tabatabai A, Bosch JA, Asara JM, Ting AY, Carr SA, McMahon AP, Perrimon N. PMID: 33888706; PMCID: PMC8062696.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    24. A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells. Elife. 2021 02 15; 10. Guo Q, Kim A, Li B, Ransick A, Bugacov H, Chen X, Lindström N, Brown A, Oxburgh L, Ren B, McMahon AP. PMID: 33587034; PMCID: PMC7924951.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    25. Author Correction: Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality. Nat Metab. 2020 09; 2(9):989. Legouis D, Ricksten SE, Faivre A, Verissimo T, Gariani K, Verney C, Galichon P, Berchtold L, Feraille E, Fernandez M, Placier S, Koppitch K, Hertig A, Martin PY, Naesens M, Pugin J, McMahon AP, Cippà PE, de Seigneux S. PMID: 32873966.
      View in: PubMed   Mentions: 1     Fields:    
    26. Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality. Nat Metab. 2020 08; 2(8):732-743. Legouis D, Ricksten SE, Faivre A, Verissimo T, Gariani K, Verney C, Galichon P, Berchtold L, Feraille E, Fernandez M, Placier S, Koppitch K, Hertig A, Martin PY, Naesens M, Pugin J, McMahon AP, Cippà PE, de Seigneux S. PMID: 32694833.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    27. A novel distal convoluted tubule-specific Cre-recombinase driven by the NaCl cotransporter gene. Am J Physiol Renal Physiol. 2020 09 01; 319(3):F423-F435. Cornelius RJ, Sharma A, Su XT, Guo JJ, McMahon JA, Ellison DH, McMahon AP, McCormick JA. PMID: 32657158; PMCID: PMC7509282.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    28. Mutational analysis of genes with ureteric progenitor cell-specific expression in branching morphogenesis of the mouse kidney. Dev Dyn. 2020 06; 249(6):765-774. Rutledge EA, McMahon AP. PMID: 32017326; PMCID: PMC7679181.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    29. Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury. J Am Soc Nephrol. 2020 04; 31(4):701-715. Liu J, Kumar S, Heinzel A, Gao M, Guo J, Alvarado GF, Reindl-Schwaighofer R, Krautzberger AM, Cippà PE, McMahon J, Oberbauer R, McMahon AP. PMID: 32034106; PMCID: PMC7191932.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    30. Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system. Dev Biol. 2020 02 15; 458(2):164-176. Rutledge EA, Lindström NO, Michos O, McMahon AP. PMID: 31734175; PMCID: PMC6995766.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    31. Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney. Dev Cell. 2019 11 04; 51(3):399-413.e7. Ransick A, Lindström NO, Liu J, Zhu Q, Guo JJ, Alvarado GF, Kim AD, Black HG, Kim J, McMahon AP. PMID: 31689386; PMCID: PMC6948019.
      View in: PubMed   Mentions: 144     Fields:    Translation:AnimalsCells
    32. Cellular Recruitment by Podocyte-Derived Pro-migratory Factors in Assembly of the Human Renal Filter. iScience. 2019 Oct 25; 20:402-414. Kim AD, Lake BB, Chen S, Wu Y, Guo J, Parvez RK, Tran T, Thornton ME, Grubbs B, McMahon JA, Zhang K, McMahon AP. PMID: 31622881; PMCID: PMC6817668.
      View in: PubMed   Mentions: 6  
    33. In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes. Dev Cell. 2019 07 01; 50(1):102-116.e6. Tran T, Lindström NO, Ransick A, De Sena Brandine G, Guo Q, Kim AD, Der B, Peti-Peterdi J, Smith AD, Thornton M, Grubbs B, McMahon JA, McMahon AP. PMID: 31265809; PMCID: PMC6684316.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    34. Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Dev Biol. 2019 10 15; 454(2):156-169. Rutledge EA, Parvez RK, Short KM, Smyth IM, McMahon AP. PMID: 31242448; PMCID: PMC6726516.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    35. A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation. Nat Commun. 2019 03 11; 10(1):1157. Cippà PE, Liu J, Sun B, Kumar S, Naesens M, McMahon AP. PMID: 30858375; PMCID: PMC6411919.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    36. Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback. Nat Commun. 2019 01 16; 10(1):239. Menshykau D, Michos O, Lang C, Conrad L, McMahon AP, Iber D. PMID: 30651543; PMCID: PMC6484223.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    37. Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment. Elife. 2018 12 05; 7. O'Brien LL, Combes AN, Short KM, Lindström NO, Whitney PH, Cullen-McEwen LA, Ju A, Abdelhalim A, Michos O, Bertram JF, Smyth IM, Little MH, McMahon AP. PMID: 30516471; PMCID: PMC6281319.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    38. Transcriptional trajectories of human kidney injury progression. JCI Insight. 2018 11 15; 3(22). Cippà PE, Sun B, Liu J, Chen L, Naesens M, McMahon AP. PMID: 30429361; PMCID: PMC6302941.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    39. Single-Cell RNA Sequencing of the Adult Mouse Kidney: From Molecular Cataloging of Cell Types to Disease-Associated Predictions. Am J Kidney Dis. 2019 01; 73(1):140-142. Lindström NO, De Sena Brandine G, Ransick A, McMahon AP. PMID: 30241960; PMCID: PMC6480390.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    40. Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through Cdk6 expression. Development. 2018 08 20; 145(17). Hasenpusch-Theil K, West S, Kelman A, Kozic Z, Horrocks S, McMahon AP, Price DJ, Mason JO, Theil T. PMID: 30093555; PMCID: PMC6141774.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    41. A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells. Stem Cell Reports. 2018 08 14; 11(2):470-484. Przepiorski A, Sander V, Tran T, Hollywood JA, Sorrenson B, Shih JH, Wolvetang EJ, McMahon AP, Holm TM, Davidson AJ. PMID: 30033089; PMCID: PMC6092837.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    42. Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis. Dev Cell. 2018 06 04; 45(5):651-660.e4. Lindström NO, De Sena Brandine G, Tran T, Ransick A, Suh G, Guo J, Kim AD, Parvez RK, Ruffins SW, Rutledge EA, Thornton ME, Grubbs B, McMahon JA, Smith AD, McMahon AP. PMID: 29870722; PMCID: PMC6510587.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    43. Disparate levels of beta-catenin activity determine nephron progenitor cell fate. Dev Biol. 2018 08 01; 440(1):13-21. Ramalingam H, Fessler AR, Das A, Valerius MT, Basta J, Robbins L, Brown AC, Oxburgh L, McMahon AP, Rauchman M, Carroll TJ. PMID: 29705331; PMCID: PMC5988999.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    44. Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions. PLoS Genet. 2018 04; 14(4):e1007346. Tan Z, Niu B, Tsang KY, Melhado IG, Ohba S, He X, Huang Y, Wang C, McMahon AP, Jauch R, Chan D, Zhang MQ, Cheah KSE. PMID: 29659575; PMCID: PMC5919691.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    45. Conserved and Divergent Features of Human and Mouse Kidney Organogenesis. J Am Soc Nephrol. 2018 03; 29(3):785-805. Lindström NO, McMahon JA, Guo J, Tran T, Guo Q, Rutledge E, Parvez RK, Saribekyan G, Schuler RE, Liao C, Kim AD, Abdelhalim A, Ruffins SW, Thornton ME, Baskin L, Grubbs B, Kesselman C, McMahon AP. PMID: 29449453; PMCID: PMC5827606.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimals
    46. Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning. J Am Soc Nephrol. 2018 03; 29(3):825-840. Lindström NO, Tran T, Guo J, Rutledge E, Parvez RK, Thornton ME, Grubbs B, McMahon JA, McMahon AP. PMID: 29449451; PMCID: PMC5827611.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    47. Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney. J Am Soc Nephrol. 2018 03; 29(3):806-824. Lindström NO, Guo J, Kim AD, Tran T, Guo Q, De Sena Brandine G, Ransick A, Parvez RK, Thornton ME, Baskin L, Grubbs B, McMahon JA, Smith AD, McMahon AP. PMID: 29449449; PMCID: PMC5827607.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    48. Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies. PLoS Genet. 2018 01; 14(1):e1007181. O'Brien LL, Guo Q, Bahrami-Samani E, Park JS, Hasso SM, Lee YJ, Fang A, Kim AD, Guo J, Hong TM, Peterson KA, Lozanoff S, Raviram R, Ren B, Fogelgren B, Smith AD, Valouev A, McMahon AP. PMID: 29377931; PMCID: PMC5805373.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    49. Development of the Human Fetal Kidney from Mid to Late Gestation in Male and Female Infants. EBioMedicine. 2018 Jan; 27:275-283. Ryan D, Sutherland MR, Flores TJ, Kent AL, Dahlstrom JE, Puelles VG, Bertram JF, McMahon AP, Little MH, Moore L, Black MJ. PMID: 29329932; PMCID: PMC5828465.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    50. An immunohistochemical identification key for cell types in adult mouse prostatic and urethral tissue sections. PLoS One. 2017; 12(11):e0188413. Wegner KA, Cadena MT, Trevena R, Turco AE, Gottschalk A, Halberg RB, Guo J, McMahon JA, McMahon AP, Vezina CM. PMID: 29145476; PMCID: PMC5690684.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    51. Determination of Total Biotin by Liquid Chromatography Coupled with Immunoaffinity Column Cleanup Extraction: Multilaboratory Testing, Final Action 2016.02. J AOAC Int. 2018 May 01; 101(3):831-842. Joseph G, Devi R, Marley EC, Leeman D, Bhandari S, Butler Thompson L, Campos Giminez E, Chen H, Dekker N, Devi R, Dole M, Gallegos-Peretz T, Gill B, Gill T, Green Y, Hodgson M, Huo X, Indyk H, Joseph G, Kennedy L, Leeman D, Lim F, Macfadzean C, McMahon A, Malaviole I, Marley E, Seegers M, Schimpf K, Wang J, Wollard D, Yadlapalli S, Yin C. PMID: 29021006.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    52. Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion. JCI Insight. 2017 09 21; 2(18). Liu J, Kumar S, Dolzhenko E, Alvarado GF, Guo J, Lu C, Chen Y, Li M, Dessing MC, Parvez RK, Cippà PE, Krautzberger AM, Saribekyan G, Smith AD, McMahon AP. PMID: 28931758; PMCID: PMC5612583.
      View in: PubMed   Mentions: 115     Fields:    Translation:Animals
    53. Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 09 01; 144(17):3177-3188. Rutledge EA, Benazet JD, McMahon AP. PMID: 28705898; PMCID: PMC5611955.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    54. Sox9 positive periosteal cells in fracture repair of the adult mammalian long bone. Bone. 2017 Oct; 103:12-19. He X, Bougioukli S, Ortega B, Arevalo E, Lieberman JR, McMahon AP. PMID: 28627474; PMCID: PMC6435293.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    55. Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 05 22; 41(4):349-365.e3. Naiman N, Fujioka K, Fujino M, Valerius MT, Potter SS, McMahon AP, Kobayashi A. PMID: 28535371; PMCID: PMC5532731.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    56. A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking. Dev Cell. 2017 03 13; 40(5):439-452.e4. Minegishi K, Hashimoto M, Ajima R, Takaoka K, Shinohara K, Ikawa Y, Nishimura H, McMahon AP, Willert K, Okada Y, Sasaki H, Shi D, Fujimori T, Ohtsuka T, Igarashi Y, Yamaguchi TP, Shimono A, Shiratori H, Hamada H. PMID: 28292423; PMCID: PMC7974384.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    57. Hedgehog Signaling: From Basic Biology to Cancer Therapy. Cell Chem Biol. 2017 Mar 16; 24(3):252-280. Wu F, Zhang Y, Sun B, McMahon AP, Wang Y. PMID: 28286127; PMCID: PMC7442121.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansCells
    58. (Re)Building a Kidney. J Am Soc Nephrol. 2017 May; 28(5):1370-1378. Oxburgh L, Carroll TJ, Cleaver O, Gossett DR, Hoshizaki DK, Hubbell JA, Humphreys BD, Jain S, Jensen J, Kaplan DL, Kesselman C, Ketchum CJ, Little MH, McMahon AP, Shankland SJ, Spence JR, Valerius MT, Wertheim JA, Wessely O, Zheng Y, Drummond IA. PMID: 28096308; PMCID: PMC5407737.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    59. Correction: Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation. PLoS Genet. 2016 Dec; 12(12):e1006533. Hoffmann AD, Yang XH, Burnicka-Turek O, Bosman JD, Ren X, Xie L, Steimle JD, Vokes SA, McMahon AP, Kalinichenko VV, Moskowitz IP. PMID: 28033319; PMCID: PMC5199006.
      View in: PubMed   Mentions:    Fields:    
    60. An Emerging Regulatory Landscape for Skeletal Development. Trends Genet. 2016 12; 32(12):774-787. Hojo H, McMahon AP, Ohba S. PMID: 27814929; PMCID: PMC5126973.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    61. AP-1 family members act with Sox9 to promote chondrocyte hypertrophy. Development. 2016 08 15; 143(16):3012-23. He X, Ohba S, Hojo H, McMahon AP. PMID: 27471255; PMCID: PMC5004882.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    62. Sonoelastography of the Achilles Tendon: Prevalence and Prognostic Value Among Asymptomatic Elite Australian Rules Football Players. Clin J Sport Med. 2016 Jul; 26(4):299-306. Ooi CC, Schneider ME, Malliaras P, Jones D, Saunders S, McMahon A, Connell D. PMID: 26513392.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    63. An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1. Elife. 2016 05 05; 5. Lorberbaum DS, Ramos AI, Peterson KA, Carpenter BS, Parker DS, De S, Hillers LE, Blake VM, Nishi Y, McFarlane MR, Chiang AC, Kassis JA, Allen BL, McMahon AP, Barolo S. PMID: 27146892; PMCID: PMC4887206.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    64. Sp7/Osterix Is Restricted to Bone-Forming Vertebrates where It Acts as a Dlx Co-factor in Osteoblast Specification. Dev Cell. 2016 05 09; 37(3):238-53. Hojo H, Ohba S, He X, Lai LP, McMahon AP. PMID: 27134141; PMCID: PMC4964983.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    65. Stem cells for all ages, yet hostage to aging. Stem Cell Investig. 2016; 3:11. Finch CE, McMahon AP. PMID: 27357142; PMCID: PMC4923636.
      View in: PubMed   Mentions:
    66. Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators. Development. 2016 Feb 15; 143(4):595-608. O'Brien LL, Guo Q, Lee Y, Tran T, Benazet JD, Whitney PH, Valouev A, McMahon AP. PMID: 26884396; PMCID: PMC4760318.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    67. Development of the Mammalian Kidney. Curr Top Dev Biol. 2016; 117:31-64. McMahon AP. PMID: 26969971; PMCID: PMC5007134.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimals
    68. Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State. Dev Cell. 2015 Nov 09; 35(3):358-65. Askary A, Mork L, Paul S, He X, Izuhara AK, Gopalakrishnan S, Ichida JK, McMahon AP, Dabizljevic S, Dale R, Mariani FV, Crump JG. PMID: 26555055; PMCID: PMC4758819.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    69. Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity. Exp Cell Res. 2016 Jan 01; 340(1):43-52. Hettmer S, Lin MM, Tchessalova D, Tortorici SJ, Castiglioni A, Desai T, Mao J, McMahon AP, Wagers AJ. PMID: 26460176; PMCID: PMC4718790.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    70. A direct fate exclusion mechanism by Sonic hedgehog-regulated transcriptional repressors. Development. 2015 Oct 01; 142(19):3286-93. Nishi Y, Zhang X, Jeong J, Peterson KA, Vedenko A, Bulyk ML, Hide WA, McMahon AP. PMID: 26293298; PMCID: PMC4631756.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    71. Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney. Cell Rep. 2015 Aug 25; 12(8):1325-38. Kumar S, Liu J, Pang P, Krautzberger AM, Reginensi A, Akiyama H, Schedl A, Humphreys BD, McMahon AP. PMID: 26279573.
      View in: PubMed   Mentions: 94     Fields:    Translation:AnimalsCells
    72. Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte. Cell Rep. 2015 Jul 14; 12(2):229-43. Ohba S, He X, Hojo H, McMahon AP. PMID: 26146088; PMCID: PMC4504750.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    73. A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning. Dev Cell. 2014 Nov 24; 31(4):448-60. Junker JP, Peterson KA, Nishi Y, Mao J, McMahon AP, van Oudenaarden A. PMID: 25458012.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    74. Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation. PLoS Genet. 2014 Oct; 10(10):e1004604. Hoffmann AD, Yang XH, Burnicka-Turek O, Bosman JD, Ren X, Steimle JD, Vokes SA, McMahon AP, Kalinichenko VV, Moskowitz IP. PMID: 25356765; PMCID: PMC4214600.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    75. Genome-wide RNA Tomography in the zebrafish embryo. Cell. 2014 Oct 23; 159(3):662-75. Junker JP, Noël ES, Guryev V, Peterson KA, Shah G, Huisken J, McMahon AP, Berezikov E, Bakkers J, van Oudenaarden A. PMID: 25417113.
      View in: PubMed   Mentions: 115     Fields:    Translation:Animals
    76. Identification of a multipotent self-renewing stromal progenitor population during mammalian kidney organogenesis. Stem Cell Reports. 2014 Oct 14; 3(4):650-62. Kobayashi A, Mugford JW, Krautzberger AM, Naiman N, Liao J, McMahon AP. PMID: 25358792; PMCID: PMC4223698.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    77. Stk11 (Lkb1) deletion in the osteoblast lineage leads to high bone turnover, increased trabecular bone density and cortical porosity. Bone. 2014 Dec; 69:98-108. Lai LP, Lotinun S, Bouxsein ML, Baron R, McMahon AP. PMID: 25240456; PMCID: PMC4373701.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    78. Induction and patterning of the metanephric nephron. Semin Cell Dev Biol. 2014 Dec; 36:31-8. O'Brien LL, McMahon AP. PMID: 25194660; PMCID: PMC4252735.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    79. Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs. Nature. 2014 Jul 03; 511(7507):46-51. Lopez-Rios J, Duchesne A, Speziale D, Andrey G, Peterson KA, Germann P, Unal E, Liu J, Floriot S, Barbey S, Gallard Y, Müller-Gerbl M, Courtney AD, Klopp C, Rodriguez S, Ivanek R, Beisel C, Wicking C, Iber D, Robert B, McMahon AP, Duboule D, Zeller R. PMID: 24990743.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    80. Defining the acute kidney injury and repair transcriptome. Semin Nephrol. 2014 Jul; 34(4):404-17. Kumar S, Liu J, McMahon AP. PMID: 25217269; PMCID: PMC4163949.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    81. Collecting duct-derived cells display mesenchymal stem cell properties and retain selective in vitro and in vivo epithelial capacity. J Am Soc Nephrol. 2015 Jan; 26(1):81-94. Li J, Ariunbold U, Suhaimi N, Sunn N, Guo J, McMahon JA, McMahon AP, Little M. PMID: 24904087; PMCID: PMC4279727.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    82. Global quantification of tissue dynamics in the developing mouse kidney. Dev Cell. 2014 Apr 28; 29(2):188-202. Short KM, Combes AN, Lefevre J, Ju AL, Georgas KM, Lamberton T, Cairncross O, Rumballe BA, McMahon AP, Hamilton NA, Smyth IM, Little MH. PMID: 24780737.
      View in: PubMed   Mentions: 121     Fields:    Translation:AnimalsCells
    83. Translational profiles of medullary myofibroblasts during kidney fibrosis. J Am Soc Nephrol. 2014 Sep; 25(9):1979-90. Grgic I, Krautzberger AM, Hofmeister A, Lalli M, DiRocco DP, Fleig SV, Liu J, Duffield JS, McMahon AP, Aronow B, Humphreys BD. PMID: 24652793; PMCID: PMC4147988.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    84. Cell-specific translational profiling in acute kidney injury. J Clin Invest. 2014 Mar; 124(3):1242-54. Liu J, Krautzberger AM, Sui SH, Hofmann OM, Chen Y, Baetscher M, Grgic I, Kumar S, Humphreys BD, Humphreys B, Hide WA, McMahon AP. PMID: 24569379; PMCID: PMC3938273.
      View in: PubMed   Mentions: 104     Fields:    Translation:AnimalsCells
    85. Defining kidney biology to understand renal disease. Clin J Am Soc Nephrol. 2014 Apr; 9(4):809-11. Little MH, Brown D, Humphreys BD, McMahon AP, Miner JH, Sands JM, Weisz OA, Mullins C, Hoshizaki D, Kidney Research National Dialogue (KRND). PMID: 24370769; PMCID: PMC3974369.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    86. A novel site comes into sight. Elife. 2013 Dec 03; 2:e01680. Wang Y, McMahon AP. PMID: 24302574; PMCID: PMC3847883.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    87. Gene regulatory networks mediating canonical Wnt signal-directed control of pluripotency and differentiation in embryo stem cells. Stem Cells. 2013 Dec; 31(12):2667-79. Zhang X, Peterson KA, Liu XS, McMahon AP, Ohba S. PMID: 23505158; PMCID: PMC3830733.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    88. Distinct cellular origin and genetic requirement of Hedgehog-Gli in postnatal rhabdomyosarcoma genesis. Oncogene. 2014 Nov 13; 33(46):5370-8. Rajurkar M, Huang H, Cotton JL, Brooks JK, Sicklick J, McMahon AP, Mao J. PMID: 24276242; PMCID: PMC4309268.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    89. Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19450-5. Lai LP, Lilley BN, Sanes JR, McMahon AP. PMID: 24218567; PMCID: PMC3845115.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    90. Mutations in Hedgehog pathway genes in fetal rhabdomyomas. J Pathol. 2013 Sep; 231(1):44-52. Hettmer S, Teot LA, van Hummelen P, MacConaill L, Bronson RT, Dall'Osso C, Mao J, McMahon AP, Gruber PJ, Grier HE, Rodriguez-Galindo C, Fletcher CD, Wagers AJ. PMID: 23780909; PMCID: PMC3875333.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    91. Retinoid signaling in progenitors controls specification and regeneration of the urothelium. Dev Cell. 2013 Sep 16; 26(5):469-482. Gandhi D, Molotkov A, Batourina E, Schneider K, Dan H, Reiley M, Laufer E, Metzger D, Liang F, Liao Y, Sun TT, Aronow B, Rosen R, Mauney J, Adam R, Rosselot C, Van Batavia J, McMahon A, McMahon J, Guo JJ, Mendelsohn C. PMID: 23993789; PMCID: PMC4024836.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    92. Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis. J Clin Invest. 2013 Sep; 123(9):4023-35. Humphreys BD, Xu F, Sabbisetti V, Grgic I, Movahedi Naini S, Wang N, Chen G, Xiao S, Patel D, Henderson JM, Ichimura T, Mou S, Soeung S, McMahon AP, Kuchroo VK, Bonventre JV. PMID: 23979159; PMCID: PMC3755983.
      View in: PubMed   Mentions: 158     Fields:    Translation:AnimalsCells
    93. Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning. Development. 2013 Aug; 140(16):3423-34. Holtz AM, Peterson KA, Nishi Y, Morin S, Song JY, Charron F, McMahon AP, Allen BL. PMID: 23900540; PMCID: PMC3737722.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    94. Wnt4/β-catenin signaling in medullary kidney myofibroblasts. J Am Soc Nephrol. 2013 Sep; 24(9):1399-412. DiRocco DP, Kobayashi A, Taketo MM, McMahon AP, Humphreys BD. PMID: 23766539; PMCID: PMC3752942.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    95. Filopodia: the cellular quills of hedgehog signaling? Dev Cell. 2013 May 28; 25(4):328-30. McMahon AP, Hasso SM. PMID: 23725760.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    96. Progenitor programming in mammalian nephrogenesis. Nephrology (Carlton). 2013 Mar; 18(3):177-9. O'Brien LL, McMahon AP. PMID: 23279704; PMCID: PMC5862531.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    97. Modeling recent human evolution in mice by expression of a selected EDAR variant. Cell. 2013 Feb 14; 152(4):691-702. Kamberov YG, Wang S, Tan J, Gerbault P, Wark A, Tan L, Yang Y, Li S, Tang K, Chen H, Powell A, Itan Y, Fuller D, Lohmueller J, Mao J, Schachar A, Paymer M, Hostetter E, Byrne E, Burnett M, McMahon AP, Thomas MG, Lieberman DE, Jin L, Tabin CJ, Morgan BA, Sabeti PC. PMID: 23415220; PMCID: PMC3575602.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansAnimalsCells
    98. Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat Commun. 2013; 4:1367. Mae SI, Shono A, Shiota F, Yasuno T, Kajiwara M, Gotoda-Nishimura N, Arai S, Sato-Otubo A, Toyoda T, Takahashi K, Nakayama N, Cowan CA, Aoi T, Ogawa S, McMahon AP, Yamanaka S, Osafune K. PMID: 23340407; PMCID: PMC4447148.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimalsCells
    99. Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. Genes Dev. 2012 Dec 15; 26(24):2802-16. Peterson KA, Nishi Y, Ma W, Vedenko A, Shokri L, Zhang X, McFarlane M, Baizabal JM, Junker JP, van Oudenaarden A, Mikkelsen T, Bernstein BE, Bailey TL, Bulyk ML, Wong WH, McMahon AP. PMID: 23249739; PMCID: PMC3533082.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    100. Germ cells are not required to establish the female pathway in mouse fetal gonads. PLoS One. 2012; 7(10):e47238. Maatouk DM, Mork L, Hinson A, Kobayashi A, McMahon AP, Capel B. PMID: 23091613; PMCID: PMC3473035.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    101. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Front Neurosci. 2012; 6:130. Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM. PMID: 22988430; PMCID: PMC3439845.
      View in: PubMed   Mentions: 15  
    102. Glucocorticoid compounds modify smoothened localization and hedgehog pathway activity. Chem Biol. 2012 Aug 24; 19(8):972-82. Wang Y, Davidow L, Arvanites AC, Blanchard J, Lam K, Xu K, Oza V, Yoo JW, Ng JM, Curran T, Rubin LL, McMahon AP. PMID: 22921064; PMCID: PMC3724998.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    103. Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks. Dev Cell. 2012 Sep 11; 23(3):637-51. Park JS, Ma W, O'Brien LL, Chung E, Guo JJ, Cheng JG, Valerius MT, McMahon JA, Wong WH, McMahon AP. PMID: 22902740; PMCID: PMC3892952.
      View in: PubMed   Mentions: 139     Fields:    Translation:AnimalsCells
    104. Invasion of distal nephron precursors associates with tubular interconnection during nephrogenesis. J Am Soc Nephrol. 2012 Oct; 23(10):1682-90. Kao RM, Vasilyev A, Miyawaki A, Drummond IA, McMahon AP. PMID: 22904347; PMCID: PMC3458467.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    105. Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12592-7. Guha A, Vasconcelos M, Cai Y, Yoneda M, Hinds A, Qian J, Li G, Dickel L, Johnson JE, Kimura S, Guo J, McMahon J, McMahon AP, Cardoso WV. PMID: 22797898; PMCID: PMC3412014.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    106. Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation. ACS Chem Biol. 2012 Jun 15; 7(6):1040-8. Wang Y, Arvanites AC, Davidow L, Blanchard J, Lam K, Yoo JW, Coy S, Rubin LL, McMahon AP. PMID: 22554036; PMCID: PMC3905677.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    107. Mammalian kidney development: principles, progress, and projections. Cold Spring Harb Perspect Biol. 2012 May 01; 4(5). Little MH, McMahon AP. PMID: 22550230; PMCID: PMC3331696.
      View in: PubMed   Mentions: 202     Fields:    Translation:HumansCells
    108. Identification of molecular compartments and genetic circuitry in the developing mammalian kidney. Development. 2012 May; 139(10):1863-73. Yu J, Valerius MT, Duah M, Staser K, Hansard JK, Guo JJ, McMahon J, Vaughan J, Faria D, Georgas K, Rumballe B, Ren Q, Krautzberger AM, Junker JP, Thiagarajan RD, Machanick P, Gray PA, van Oudenaarden A, Rowitch DH, Stiles CD, Ma Q, Grimmond SM, Bailey TL, Little MH, McMahon AP. PMID: 22510988; PMCID: PMC3328182.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    109. The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis. Proc Natl Acad Sci U S A. 2012 Apr 24; 109(17):E1038-47. Rajurkar M, De Jesus-Monge WE, Driscoll DR, Appleman VA, Huang H, Cotton JL, Klimstra DS, Zhu LJ, Simin K, Xu L, McMahon AP, Lewis BC, Mao J. PMID: 22493246; PMCID: PMC3340052.
      View in: PubMed   Mentions: 62     Fields:    Translation:Animals
    110. Hedgehog-Gli pathway activation during kidney fibrosis. Am J Pathol. 2012 Apr; 180(4):1441-53. Fabian SL, Penchev RR, St-Jacques B, Rao AN, Sipilä P, West KA, McMahon AP, Humphreys BD. PMID: 22342522; PMCID: PMC3349903.
      View in: PubMed   Mentions: 104     Fields:    Translation:AnimalsCells
    111. Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice. Biol Reprod. 2012 Feb; 86(2):37. Mork L, Maatouk DM, McMahon JA, Guo JJ, Zhang P, McMahon AP, Capel B. PMID: 21976597; PMCID: PMC3290667.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    112. Signaling by SHH rescues facial defects following blockade in the brain. Dev Dyn. 2012 Feb; 241(2):247-56. Chong HJ, Young NM, Hu D, Jeong J, McMahon AP, Hallgrimsson B, Marcucio RS. PMID: 22275045; PMCID: PMC3547623.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    113. An embryonic stem cell-based system for rapid analysis of transcriptional enhancers. Genesis. 2012 May; 50(5):443-50. Tsanov KM, Nishi Y, Peterson KA, Liu J, Baetscher M, McMahon AP. PMID: 22083581; PMCID: PMC3334447.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    114. Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells. Development. 2011 Oct; 138(19):4245-54. Boyle SC, Kim M, Valerius MT, McMahon AP, Kopan R. PMID: 21852398; PMCID: PMC3171224.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    115. The GUDMAP database--an online resource for genitourinary research. Development. 2011 Jul; 138(13):2845-53. Harding SD, Armit C, Armstrong J, Brennan J, Cheng Y, Haggarty B, Houghton D, Lloyd-MacGilp S, Pi X, Roochun Y, Sharghi M, Tindal C, McMahon AP, Gottesman B, Little MH, Georgas K, Aronow BJ, Potter SS, Brunskill EW, Southard-Smith EM, Mendelsohn C, Baldock RA, Davies JA, Davidson D. PMID: 21652655; PMCID: PMC3188593.
      View in: PubMed   Mentions: 145     Fields:    Translation:HumansAnimals
    116. Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation. Dev Cell. 2011 Jun 14; 20(6):788-801. Izzi L, Lévesque M, Morin S, Laniel D, Wilkes BC, Mille F, Krauss RS, McMahon AP, Allen BL, Charron F. PMID: 21664577; PMCID: PMC3432913.
      View in: PubMed   Mentions: 134     Fields:    Translation:AnimalsCells
    117. Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function. Dev Cell. 2011 Jun 14; 20(6):775-87. Allen BL, Song JY, Izzi L, Althaus IW, Kang JS, Charron F, Krauss RS, McMahon AP. PMID: 21664576; PMCID: PMC3121104.
      View in: PubMed   Mentions: 150     Fields:    Translation:AnimalsCells
    118. A low resistance microfluidic system for the creation of stable concentration gradients in a defined 3D microenvironment. Biomed Microdevices. 2010 Dec; 12(6):1027-41. Amadi OC, Steinhauser ML, Nishi Y, Chung S, Kamm RD, McMahon AP, Lee RT. PMID: 20661647; PMCID: PMC3119200.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    119. Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney. Kidney Int. 2011 Feb; 79(3):317-30. Nagalakshmi VK, Ren Q, Pugh MM, Valerius MT, McMahon AP, Yu J. PMID: 20944551; PMCID: PMC3214622.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    120. Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9736-41. Lee EY, Ji H, Ouyang Z, Zhou B, Ma W, Vokes SA, McMahon AP, Wong WH, Scott MP. PMID: 20460306; PMCID: PMC2906878.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    121. Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract. Development. 2010 May; 137(10):1721-9. Mao J, Kim BM, Rajurkar M, Shivdasani RA, McMahon AP. PMID: 20430747; PMCID: PMC2860252.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    122. Macrophage Wnt7b is critical for kidney repair and regeneration. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4194-9. Lin SL, Li B, Rao S, Yeo EJ, Hudson TE, Nowlin BT, Pei H, Chen L, Zheng JJ, Carroll TJ, Pollard JW, McMahon AP, Lang RA, Duffield JS. PMID: 20160075; PMCID: PMC2840080.
      View in: PubMed   Mentions: 215     Fields:    Translation:AnimalsCells
    123. Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal. Genes Dev. 2010 Feb 01; 24(3):312-26. Niakan KK, Ji H, Maehr R, Vokes SA, Rodolfa KT, Sherwood RI, Yamaki M, Dimos JT, Chen AE, Melton DA, McMahon AP, Eggan K. PMID: 20123909; PMCID: PMC2811832.
      View in: PubMed   Mentions: 140     Fields:    Translation:AnimalsCells
    124. Using mechanistic Bayesian networks to identify downstream targets of the sonic hedgehog pathway. BMC Bioinformatics. 2009 Dec 18; 10:433. Shah A, Tenzen T, McMahon AP, Woolf PJ. PMID: 20021670; PMCID: PMC3087349.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    125. Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol. 2010 Jan; 176(1):85-97. Humphreys BD, Lin SL, Kobayashi A, Hudson TE, Nowlin BT, Bonventre JV, Valerius MT, McMahon AP, Duffield JS. PMID: 20008127; PMCID: PMC2797872.
      View in: PubMed   Mentions: 711     Fields:    Translation:AnimalsCells
    126. An Hh-dependent pathway in lateral plate mesoderm enables the generation of left/right asymmetry. Curr Biol. 2009 Dec 01; 19(22):1912-7. Tsiairis CD, McMahon AP. PMID: 19879143; PMCID: PMC2787870.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    127. Hedgehog signalling: Kif7 is not that fishy after all. Curr Biol. 2009 Sep 15; 19(17):R729-31. Ingham PW, McMahon AP. PMID: 19906571.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    128. High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population. Dev Biol. 2009 Sep 15; 333(2):312-23. Mugford JW, Yu J, Kobayashi A, McMahon AP. PMID: 19591821; PMCID: PMC2748313.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    129. Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Dev Biol. 2009 Aug 15; 332(2):273-86. Georgas K, Rumballe B, Valerius MT, Chiu HS, Thiagarajan RD, Lesieur E, Aronow BJ, Brunskill EW, Combes AN, Tang D, Taylor D, Grimmond SM, Potter SS, McMahon AP, Little MH. PMID: 19501082.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimals
    130. Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell Stem Cell. 2009 Jun 05; 4(6):559-67. Hofmann I, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Cornejo MG, Okabe R, Armstrong SA, Ghilardi N, Gould S, de Sauvage FJ, McMahon AP, Gilliland DG. PMID: 19497284; PMCID: PMC3065323.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    131. Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb. Dev Cell. 2009 Apr; 16(4):600-6. Mao J, McGlinn E, Huang P, Tabin CJ, McMahon AP. PMID: 19386268; PMCID: PMC3164484.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    132. Modeling the spatio-temporal network that drives patterning in the vertebrate central nervous system. Biochim Biophys Acta. 2009 Apr; 1789(4):299-305. Nishi Y, Ji H, Wong WH, McMahon AP, Vokes SA. PMID: 19445894.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    133. Motor neurons with axial muscle projections specified by Wnt4/5 signaling. Neuron. 2009 Mar 12; 61(5):708-20. Agalliu D, Takada S, Agalliu I, McMahon AP, Jessell TM. PMID: 19285468; PMCID: PMC2741579.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    134. Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2623-8. Wang Y, Zhou Z, Walsh CT, McMahon AP. PMID: 19196978; PMCID: PMC2650314.
      View in: PubMed   Mentions: 98     Fields:    Translation:AnimalsCells
    135. A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney. Development. 2009 Jan; 136(1):161-71. Yu J, Carroll TJ, Rajagopal J, Kobayashi A, Ren Q, McMahon AP. PMID: 19060336; PMCID: PMC2685965.
      View in: PubMed   Mentions: 128     Fields:    Translation:AnimalsCells
    136. Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature. Science. 2008 Nov 21; 322(5905):1247-50. Stenman JM, Rajagopal J, Carroll TJ, Ishibashi M, McMahon J, McMahon AP. PMID: 19023080.
      View in: PubMed   Mentions: 329     Fields:    Translation:AnimalsCells
    137. Atlas of gene expression in the developing kidney at microanatomic resolution. Dev Cell. 2008 Nov; 15(5):781-91. Brunskill EW, Aronow BJ, Georgas K, Rumballe B, Valerius MT, Aronow J, Kaimal V, Jegga AG, Yu J, Grimmond S, McMahon AP, Patterson LT, Little MH, Potter SS. PMID: 19000842; PMCID: PMC2653061.
      View in: PubMed   Mentions: 125     Fields:    Translation:Animals
    138. Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways. Proc Natl Acad Sci U S A. 2008 Nov 04; 105(44):16976-81. Wu JY, Purton LE, Rodda SJ, Chen M, Weinstein LS, McMahon AP, Scadden DT, Kronenberg HM. PMID: 18957542; PMCID: PMC2579363.
      View in: PubMed   Mentions: 117     Fields:    Translation:AnimalsCells
    139. A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb. Genes Dev. 2008 Oct 01; 22(19):2651-63. Vokes SA, Ji H, Wong WH, McMahon AP. PMID: 18832070; PMCID: PMC2559910.
      View in: PubMed   Mentions: 180     Fields:    Translation:AnimalsCells
    140. Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney. Dev Biol. 2008 Dec 01; 324(1):88-98. Mugford JW, Sipilä P, McMahon JA, McMahon AP. PMID: 18835385; PMCID: PMC2642884.
      View in: PubMed   Mentions: 151     Fields:    Translation:AnimalsCells
    141. Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell. 2008 Aug 12; 14(2):123-34. Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL. PMID: 18691547; PMCID: PMC2597270.
      View in: PubMed   Mentions: 349     Fields:    Translation:HumansAnimalsCells
    142. Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell. 2008 Aug 07; 3(2):169-81. Kobayashi A, Valerius MT, Mugford JW, Carroll TJ, Self M, Oliver G, McMahon AP. PMID: 18682239; PMCID: PMC2561900.
      View in: PubMed   Mentions: 495     Fields:    Translation:AnimalsCells
    143. Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network. Development. 2008 Aug; 135(15):2489-503. Dessaud E, McMahon AP, Briscoe J. PMID: 18621990.
      View in: PubMed   Mentions: 351     Fields:    Translation:Animals
    144. Developmental biology. Grasping limb patterning. Science. 2008 Jul 18; 321(5887):350-2. Tabin CJ, McMahon AP. PMID: 18635784.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    145. An eight residue fragment of an acyl carrier protein suffices for post-translational introduction of fluorescent pantetheinyl arms in protein modification in vitro and in vivo. J Am Chem Soc. 2008 Jul 30; 130(30):9925-30. Zhou Z, Koglin A, Wang Y, McMahon AP, Walsh CT. PMID: 18593165; PMCID: PMC2561316.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    146. Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease. Genes Dev. 2008 Jun 15; 22(12):1662-76. Walkley CR, Qudsi R, Sankaran VG, Perry JA, Gostissa M, Roth SI, Rodda SJ, Snay E, Dunning P, Fahey FH, Alt FW, McMahon AP, Orkin SH. PMID: 18559481; PMCID: PMC2428063.
      View in: PubMed   Mentions: 206     Fields:    Translation:HumansAnimals
    147. In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation. J Biol Chem. 2008 Jul 25; 283(30):21002-10. Shimada M, Greer PA, McMahon AP, Bouxsein ML, Schipani E. PMID: 18515801; PMCID: PMC2475719.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    148. Indian hedgehog signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye. Dev Biol. 2008 Aug 01; 320(1):242-55. Dakubo GD, Mazerolle C, Furimsky M, Yu C, St-Jacques B, McMahon AP, Wallace VA. PMID: 18582859.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    149. Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo. Dev Biol. 2008 Jul 15; 319(2):396-405. Mugford JW, Sipilä P, Kobayashi A, Behringer RR, McMahon AP. PMID: 18485340; PMCID: PMC2580739.
      View in: PubMed   Mentions: 52     Fields:    Translation:Animals
    150. Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme. Development. 2008 May; 135(9):1625-34. Rajagopal J, Carroll TJ, Guseh JS, Bores SA, Blank LJ, Anderson WJ, Yu J, Zhou Q, McMahon AP, Melton DA. PMID: 18367557; PMCID: PMC2556060.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    151. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell. 2008 Mar 06; 2(3):284-91. Humphreys BD, Valerius MT, Kobayashi A, Mugford JW, Soeung S, Duffield JS, McMahon AP, Bonventre JV. PMID: 18371453.
      View in: PubMed   Mentions: 394     Fields:    Translation:AnimalsCells
    152. Disp1 regulates growth of mammalian long bones through the control of Ihh distribution. Dev Biol. 2008 May 15; 317(2):480-5. Tsiairis CD, McMahon AP. PMID: 18395198; PMCID: PMC2430380.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    153. GUDMAP: the genitourinary developmental molecular anatomy project. J Am Soc Nephrol. 2008 Apr; 19(4):667-71. McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project. PMID: 18287559.
      View in: PubMed   Mentions: 150     Fields:    Translation:Animals
    154. Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning. Development. 2008 Mar; 135(6):1097-106. Chamberlain CE, Jeong J, Guo C, Allen BL, McMahon AP. PMID: 18272593.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    155. Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation. Gene Expr Patterns. 2008 May; 8(5):297-306. Valerius MT, McMahon AP. PMID: 18346943; PMCID: PMC2435058.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    156. Dicer-dependent pathways regulate chondrocyte proliferation and differentiation. Proc Natl Acad Sci U S A. 2008 Feb 12; 105(6):1949-54. Kobayashi T, Lu J, Cobb BS, Rodda SJ, McMahon AP, Schipani E, Merkenschlager M, Kronenberg HM. PMID: 18238902; PMCID: PMC2538863.
      View in: PubMed   Mentions: 178     Fields:    Translation:AnimalsCells
    157. Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state. Dev Biol. 2008 Feb 01; 314(1):112-26. Marose TD, Merkel CE, McMahon AP, Carroll TJ. PMID: 18177851; PMCID: PMC2699621.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    158. The cdx genes and retinoic acid control the positioning and segmentation of the zebrafish pronephros. PLoS Genet. 2007 Oct; 3(10):1922-38. Wingert RA, Selleck R, Yu J, Song HD, Chen Z, Song A, Zhou Y, Thisse B, Thisse C, McMahon AP, Davidson AJ. PMID: 17953490; PMCID: PMC2042002.
      View in: PubMed   Mentions: 176     Fields:    Translation:AnimalsCells
    159. Wnt3 signaling in the epiblast is required for proper orientation of the anteroposterior axis. Dev Biol. 2007 Dec 01; 312(1):312-20. Barrow JR, Howell WD, Rule M, Hayashi S, Thomas KR, Capecchi MR, McMahon AP. PMID: 18028899.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    160. Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen. Development. 2007 Oct; 134(20):3603-13. Kim BM, Miletich I, Mao J, McMahon AP, Sharpe PA, Shivdasani RA. PMID: 17855428.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    161. Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Nat Genet. 2007 Oct; 39(10):1225-34. Zhou W, Lin L, Majumdar A, Li X, Zhang X, Liu W, Etheridge L, Shi Y, Martin J, Van de Ven W, Kaartinen V, Wynshaw-Boris A, McMahon AP, Rosenfeld MG, Evans SM. PMID: 17767158; PMCID: PMC5578467.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    162. Regulation of skeletogenic differentiation in cranial dermal bone. Development. 2007 Sep; 134(17):3133-44. Abzhanov A, Rodda SJ, McMahon AP, Tabin CJ. PMID: 17670790.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    163. Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development. Development. 2007 Jul; 134(13):2533-9. Park JS, Valerius MT, McMahon AP. PMID: 17537789.
      View in: PubMed   Mentions: 196     Fields:    Translation:AnimalsCells
    164. The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development. Genes Dev. 2007 May 15; 21(10):1244-57. Allen BL, Tenzen T, McMahon AP. PMID: 17504941; PMCID: PMC1865495.
      View in: PubMed   Mentions: 142     Fields:    Translation:AnimalsCells
    165. Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning. Development. 2007 May; 134(10):1977-89. Vokes SA, Ji H, McCuine S, Tenzen T, Giles S, Zhong S, Longabaugh WJ, Davidson EH, Wong WH, McMahon AP. PMID: 17442700.
      View in: PubMed   Mentions: 167     Fields:    Translation:AnimalsCells
    166. A high-resolution anatomical ontology of the developing murine genitourinary tract. Gene Expr Patterns. 2007 Jun; 7(6):680-99. Little MH, Brennan J, Georgas K, Davies JA, Davidson DR, Baldock RA, Beverdam A, Bertram JF, Capel B, Chiu HS, Clements D, Cullen-McEwen L, Fleming J, Gilbert T, Herzlinger D, Houghton D, Kaufman MH, Kleymenova E, Koopman PA, Lewis AG, McMahon AP, Mendelsohn CL, Mitchell EK, Rumballe BA, Sweeney DE, Valerius MT, Yamada G, Yang Y, Yu J. PMID: 17452023; PMCID: PMC2117077.
      View in: PubMed   Mentions: 78     Fields:    Translation:Animals
    167. Shifting paradigms in Hedgehog signaling. Curr Opin Cell Biol. 2007 Apr; 19(2):159-65. Wang Y, McMahon AP, Allen BL. PMID: 17303409.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    168. Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development. 2007 Feb; 134(4):801-11. Cheng HT, Kim M, Valerius MT, Surendran K, Schuster-Gossler K, Gossler A, McMahon AP, Kopan R. PMID: 17229764; PMCID: PMC2613851.
      View in: PubMed   Mentions: 174     Fields:    Translation:Animals
    169. Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Dev Cell. 2007 Jan; 12(1):99-112. Gritli-Linde A, Hallberg K, Harfe BD, Reyahi A, Kannius-Janson M, Nilsson J, Cobourne MT, Sharpe PT, McMahon AP, Linde A. PMID: 17199044; PMCID: PMC1885956.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    170. Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation. Dev Cell. 2007 Jan; 12(1):113-27. Tu X, Joeng KS, Nakayama KI, Nakayama K, Rajagopal J, Carroll TJ, McMahon AP, Long F. PMID: 17199045; PMCID: PMC1861818.
      View in: PubMed   Mentions: 144     Fields:    Translation:AnimalsCells
    171. A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway. Cancer Res. 2006 Oct 15; 66(20):10171-8. Mao J, Ligon KL, Rakhlin EY, Thayer SP, Bronson RT, Rowitch D, McMahon AP. PMID: 17047082; PMCID: PMC3806052.
      View in: PubMed   Mentions: 175     Fields:    Translation:Animals
    172. Wnt9b is the mutated gene involved in multifactorial nonsyndromic cleft lip with or without cleft palate in A/WySn mice, as confirmed by a genetic complementation test. Birth Defects Res A Clin Mol Teratol. 2006 Aug; 76(8):574-9. Juriloff DM, Harris MJ, McMahon AP, Carroll TJ, Lidral AC. PMID: 16998816.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimals
    173. Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors. Development. 2006 Aug; 133(16):3231-44. Rodda SJ, McMahon AP. PMID: 16854976.
      View in: PubMed   Mentions: 540     Fields:    Translation:AnimalsCells
    174. Control of transcription factor activity and osteoblast differentiation in mammalian cells using an evolved small-molecule-dependent intein. J Am Chem Soc. 2006 Jul 12; 128(27):8939-46. Yuen CM, Rodda SJ, Vokes SA, McMahon AP, Liu DR. PMID: 16819890; PMCID: PMC2519127.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    175. Independent regulation of skeletal growth by Ihh and IGF signaling. Dev Biol. 2006 Oct 01; 298(1):327-33. Long F, Joeng KS, Xuan S, Efstratiadis A, McMahon AP. PMID: 16905129.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    176. Reproducible and inducible knockdown of gene expression in mice. Genesis. 2006 May; 44(5):252-61. Yu J, McMahon AP. PMID: 16676321.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    177. The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice. Dev Cell. 2006 May; 10(5):647-56. Tenzen T, Allen BL, Cole F, Kang JS, Krauss RS, McMahon AP. PMID: 16647304.
      View in: PubMed   Mentions: 179     Fields:    Translation:AnimalsCells
    178. Retraction: Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse. Development. 2005 Dec; 132(24):5615. McMahon AP, Tian H, Tenzen T. PMID: 16314492.
      View in: PubMed   Mentions:    Fields:    
    179. BMP signaling stimulates cellular differentiation at multiple steps during cartilage development. Proc Natl Acad Sci U S A. 2005 Dec 13; 102(50):18023-7. Kobayashi T, Lyons KM, McMahon AP, Kronenberg HM. PMID: 16322106; PMCID: PMC1312369.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    180. A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nat Genet. 2005 Dec; 37(12):1323-32. Nybakken K, Vokes SA, Lin TY, McMahon AP, Perrimon N. PMID: 16311596; PMCID: PMC6429564.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    181. An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo. Nucleic Acids Res. 2005 Oct 12; 33(18):e155. Mao J, Barrow J, McMahon J, Vaughan J, McMahon AP. PMID: 16221970; PMCID: PMC1253836.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    182. Noggin antagonism of BMP4 signaling controls development of the axial skeleton in the mouse. Dev Biol. 2005 Oct 01; 286(1):149-57. Wijgerde M, Karp S, McMahon J, McMahon AP. PMID: 16122729.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    183. Binding hot spot for invasion inhibitory molecules on Plasmodium falciparum apical membrane antigen 1. Infect Immun. 2005 Oct; 73(10):6981-9. Harris KS, Casey JL, Coley AM, Masciantonio R, Sabo JK, Keizer DW, Lee EF, McMahon A, Norton RS, Anders RF, Foley M. PMID: 16177378; PMCID: PMC1230972.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    184. Apoptosis induced by vitamin A signaling is crucial for connecting the ureters to the bladder. Nat Genet. 2005 Oct; 37(10):1082-9. Batourina E, Tsai S, Lambert S, Sprenkle P, Viana R, Dutta S, Hensle T, Wang F, Niederreither K, McMahon AP, Carroll TJ, Mendelsohn CL. PMID: 16186816.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    185. Fate-mapping of the epithelial seam during palatal fusion rules out epithelial-mesenchymal transformation. Dev Biol. 2005 Sep 15; 285(2):490-5. Vaziri Sani F, Hallberg K, Harfe BD, McMahon AP, Linde A, Gritli-Linde A. PMID: 16109396.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    186. WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature. 2005 Sep 15; 437(7057):417-21. Lobov IB, Rao S, Carroll TJ, Vallance JE, Ito M, Ondr JK, Kurup S, Glass DA, Patel MS, Shu W, Morrisey EE, McMahon AP, Karsenty G, Lang RA. PMID: 16163358; PMCID: PMC4259146.
      View in: PubMed   Mentions: 204     Fields:    Translation:AnimalsCells
    187. Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell. 2005 Aug; 9(2):283-92. Carroll TJ, Park JS, Hayashi S, Majumdar A, McMahon AP. PMID: 16054034.
      View in: PubMed   Mentions: 390     Fields:    Translation:AnimalsCells
    188. Neural crest origins of the neck and shoulder. Nature. 2005 Jul 21; 436(7049):347-55. Matsuoka T, Ahlberg PE, Kessaris N, Iannarelli P, Dennehy U, Richardson WD, McMahon AP, Koentges G. PMID: 16034409; PMCID: PMC1352163.
      View in: PubMed   Mentions: 199     Fields:    Translation:HumansAnimalsCells
    189. Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP. J Clin Invest. 2005 Jul; 115(7):1734-42. Kobayashi T, Soegiarto DW, Yang Y, Lanske B, Schipani E, McMahon AP, Kronenberg HM. PMID: 15951842; PMCID: PMC1143590.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    190. Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development. Development. 2005 Jun; 132(12):2809-23. Kobayashi A, Kwan KM, Carroll TJ, McMahon AP, Mendelsohn CL, Behringer RR. PMID: 15930111.
      View in: PubMed   Mentions: 166     Fields:    Translation:Animals
    191. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005 May; 8(5):751-64. Glass DA, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G. PMID: 15866165.
      View in: PubMed   Mentions: 639     Fields:    Translation:AnimalsCells
    192. Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Dev Cell. 2005 Feb; 8(2):229-39. Basson MA, Akbulut S, Watson-Johnson J, Simon R, Carroll TJ, Shakya R, Gross I, Martin GR, Lufkin T, McMahon AP, Wilson PD, Costantini FD, Mason IJ, Licht JD. PMID: 15691764.
      View in: PubMed   Mentions: 179     Fields:    Translation:HumansAnimalsCells
    193. Mouse brain organization revealed through direct genome-scale TF expression analysis. Science. 2004 Dec 24; 306(5705):2255-7. Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q. PMID: 15618518.
      View in: PubMed   Mentions: 232     Fields:    Translation:Animals
    194. Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1. Development. 2005 Jan; 132(1):143-54. Jeong J, McMahon AP. PMID: 15576403.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    195. Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand. Development. 2005 Jan; 132(1):133-42. Tian H, Jeong J, Harfe BD, Tabin CJ, McMahon AP. PMID: 15576405.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    196. Recent genetic studies of mouse kidney development. Curr Opin Genet Dev. 2004 Oct; 14(5):550-7. Yu J, McMahon AP, Valerius MT. PMID: 15380247.
      View in: PubMed   Mentions: 44     Fields:    Translation:Animals
    197. Temporal requirement for hedgehog signaling in ventral telencephalic patterning. Development. 2004 Oct; 131(20):5031-40. Fuccillo M, Rallu M, McMahon AP, Fishell G. PMID: 15371303.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    198. Hedgehog signaling: iguana debuts as a nuclear gatekeeper. Curr Biol. 2004 Aug 24; 14(16):R668-70. Vokes SA, McMahon AP. PMID: 15324687.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    199. Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell. 2004 Aug 20; 118(4):517-28. Harfe BD, Scherz PJ, Nissim S, Tian H, McMahon AP, Tabin CJ. PMID: 15315763.
      View in: PubMed   Mentions: 504     Fields:    Translation:AnimalsCells
    200. Hedgehog signaling is essential for endothelial tube formation during vasculogenesis. Development. 2004 Sep; 131(17):4371-80. Vokes SA, Yatskievych TA, Heimark RL, McMahon J, McMahon AP, Antin PB, Krieg PA. PMID: 15294868.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    201. Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse. Development. 2004 Aug; 131(16):4021-33. Tian H, Tenzen T, McMahon AP. PMID: 15269168.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    202. The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells. Science. 2004 Jul 16; 305(5682):396-9. Scherz PJ, Harfe BD, McMahon AP, Tabin CJ. PMID: 15256670.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    203. Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Dev Biol. 2004 Jun 15; 270(2):393-410. Lewis PM, Gritli-Linde A, Smeyne R, Kottmann A, McMahon AP. PMID: 15183722.
      View in: PubMed   Mentions: 177     Fields:    Translation:AnimalsCells
    204. Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. J Clin Invest. 2004 Jun; 113(12):1692-700. Rice R, Spencer-Dene B, Connor EC, Gritli-Linde A, McMahon AP, Dickson C, Thesleff I, Rice DP. PMID: 15199404; PMCID: PMC420504.
      View in: PubMed   Mentions: 171     Fields:    Translation:AnimalsCells
    205. Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes Dev. 2004 Apr 15; 18(8):937-51. Jeong J, Mao J, Tenzen T, Kottmann AH, McMahon AP. PMID: 15107405; PMCID: PMC395852.
      View in: PubMed   Mentions: 319     Fields:    Translation:HumansAnimalsCells
    206. Derivation of embryonic stem-cell lines from human blastocysts. N Engl J Med. 2004 Mar 25; 350(13):1353-6. Cowan CA, Klimanskaya I, McMahon J, Atienza J, Witmyer J, Zucker JP, Wang S, Morton CC, McMahon AP, Powers D, Melton DA. PMID: 14999088.
      View in: PubMed   Mentions: 276     Fields:    Translation:HumansCells
    207. SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult. Dev Neurosci. 2004 Mar-Aug; 26(2-4):148-65. Ellis P, Fagan BM, Magness ST, Hutton S, Taranova O, Hayashi S, McMahon A, Rao M, Pevny L. PMID: 15711057.
      View in: PubMed   Mentions: 329     Fields:    Translation:AnimalsCells
    208. Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development. 2004 Mar; 131(6):1309-18. Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP. PMID: 14973297.
      View in: PubMed   Mentions: 176     Fields:    Translation:AnimalsCells
    209. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science. 2003 Oct 03; 302(5642):113-7. Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH, Julien JP, Goldstein LS, Cleveland DW. PMID: 14526083.
      View in: PubMed   Mentions: 402     Fields:    Translation:HumansAnimalsCells
    210. Maternal inheritance of Cre activity in a Sox2Cre deleter strain. Genesis. 2003 Oct; 37(2):51-3. Hayashi S, Tenzen T, McMahon AP. PMID: 14595839.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    211. Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron. 2003 Sep 11; 39(6):937-50. Machold R, Hayashi S, Rutlin M, Muzumdar MD, Nery S, Corbin JG, Gritli-Linde A, Dellovade T, Porter JA, Rubin LL, Dudek H, McMahon AP, Fishell G. PMID: 12971894.
      View in: PubMed   Mentions: 271     Fields:    Translation:AnimalsCells
    212. Combined activities of hedgehog signaling inhibitors regulate pancreas development. Development. 2003 Oct; 130(20):4871-9. Kawahira H, Ma NH, Tzanakakis ES, McMahon AP, Chuang PT, Hebrok M. PMID: 12917290.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    213. Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance. J Clin Invest. 2003 Aug; 112(4):554-65. Rubera I, Loffing J, Palmer LG, Frindt G, Fowler-Jaeger N, Sauter D, Carroll T, McMahon A, Hummler E, Rossier BC. PMID: 12925696; PMCID: PMC171384.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    214. Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development. Development. 2003 Jul; 130(13):2967-80. Dakubo GD, Wang YP, Mazerolle C, Campsall K, McMahon AP, Wallace VA. PMID: 12756179.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    215. Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Development. 2003 Jul; 130(14):3175-85. Majumdar A, Vainio S, Kispert A, McMahon J, McMahon AP. PMID: 12783789.
      View in: PubMed   Mentions: 201     Fields:    Translation:AnimalsCells
    216. Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia. Development. 2003 May; 130(10):2275-87. Ligon KL, Echelard Y, Assimacopoulos S, Danielian PS, Kaing S, Grove EA, McMahon AP, Rowitch DH. PMID: 12668639.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    217. FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. EMBO J. 2003 Apr 15; 22(8):1811-23. Trokovic R, Trokovic N, Hernesniemi S, Pirvola U, Vogt Weisenhorn DM, Rossant J, McMahon AP, Wurst W, Partanen J. PMID: 12682014; PMCID: PMC154461.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    218. The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell. 2003 Apr 04; 113(1):11-23. Charron F, Stein E, Jeong J, McMahon AP, Tessier-Lavigne M. PMID: 12679031.
      View in: PubMed   Mentions: 256     Fields:    Translation:AnimalsCells
    219. Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev. 2003 Feb 01; 17(3):394-409. Barrow JR, Thomas KR, Boussadia-Zahui O, Moore R, Kemler R, Capecchi MR, McMahon AP. PMID: 12569130; PMCID: PMC195987.
      View in: PubMed   Mentions: 113     Fields:    Translation:AnimalsCells
    220. Branching morphogenesis of the lung: new molecular insights into an old problem. Trends Cell Biol. 2003 Feb; 13(2):86-91. Chuang PT, McMahon AP. PMID: 12559759.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    221. Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung. Genes Dev. 2003 Feb 01; 17(3):342-7. Chuang PT, Kawcak T, McMahon AP. PMID: 12569124; PMCID: PMC195990.
      View in: PubMed   Mentions: 131     Fields:    Translation:AnimalsCells
    222. Developmental roles and clinical significance of hedgehog signaling. Curr Top Dev Biol. 2003; 53:1-114. McMahon AP, Ingham PW, Tabin CJ. PMID: 12509125.
      View in: PubMed   Mentions: 369     Fields:    Translation:HumansAnimals
    223. Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Mech Dev. 2002 Dec; 119 Suppl 1:S97-S101. Hayashi S, Lewis P, Pevny L, McMahon AP. PMID: 14516668.
      View in: PubMed   Mentions: 255     Fields:    Translation:Animals
    224. Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Gene Expr Patterns. 2002 Nov; 2(1-2):93-7. Hayashi S, Lewis P, Pevny L, McMahon AP. PMID: 12617844.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    225. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol. 2002 Apr 15; 244(2):305-18. Hayashi S, McMahon AP. PMID: 11944939.
      View in: PubMed   Mentions: 777     Fields:    Translation:Animals
    226. Wnt-1 and Wnt-4 regulate thymic cellularity. Eur J Immunol. 2002 04; 32(4):967-71. Mulroy T, McMahon JA, Burakoff SJ, McMahon AP, Sen J. PMID: 11920562.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    227. Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes. Mech Dev. 2002 Feb; 111(1-2):75-87. Heanue TA, Davis RJ, Rowitch DH, Kispert A, McMahon AP, Mardon G, Tabin CJ. PMID: 11804780.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    228. Hedgehog is required for murine yolk sac angiogenesis. Development. 2002 Jan; 129(2):361-72. Byrd N, Becker S, Maye P, Narasimhaiah R, St-Jacques B, Zhang X, McMahon J, McMahon A, Grabel L. PMID: 11807029.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    229. Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development. 2001 Dec; 128(24):5099-108. Long F, Zhang XM, Karp S, Yang Y, McMahon AP. PMID: 11748145.
      View in: PubMed   Mentions: 324     Fields:    Translation:AnimalsCells
    230. Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 2001 Dec 01; 15(23):3059-87. Ingham PW, McMahon AP. PMID: 11731473.
      View in: PubMed   Mentions: 1190     Fields:    Translation:HumansAnimalsCells
    231. BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation. Development. 2001 Nov; 128(22):4523-34. Minina E, Wenzel HM, Kreschel C, Karp S, Gaffield W, McMahon AP, Vortkamp A. PMID: 11714677.
      View in: PubMed   Mentions: 167     Fields:    Translation:AnimalsCells
    232. Wnt7b regulates placental development in mice. Dev Biol. 2001 Sep 15; 237(2):324-32. Parr BA, Cornish VA, Cybulsky MI, McMahon AP. PMID: 11543617.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    233. Developmental biology. Vesicles and the spinal cord. Nature. 2001 Jul 12; 412(6843):136-7. Jeong J, McMahon AP. PMID: 11449254.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    234. Six3 promotes the formation of ectopic optic vesicle-like structures in mouse embryos. Dev Dyn. 2001 Jul; 221(3):342-9. Lagutin O, Zhu CC, Furuta Y, Rowitch DH, McMahon AP, Oliver G. PMID: 11458394.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    235. Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R asymmetry by the mouse node. Cell. 2001 Jun 15; 105(6):781-92. Zhang XM, Ramalho-Santos M, McMahon AP. PMID: 11440720.
      View in: PubMed   Mentions: 113     Fields:    Translation:AnimalsCells
    236. Activation of expression of hedgehog target genes in basal cell carcinomas. J Invest Dermatol. 2001 May; 116(5):739-42. Bonifas JM, Pennypacker S, Chuang PT, McMahon AP, Williams M, Rosenthal A, De Sauvage FJ, Epstein EH. PMID: 11348463.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    237. Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development. 2001 Apr; 128(8):1253-64. Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, McMahon AP, Sommer L, Boussadia O, Kemler R. PMID: 11262227.
      View in: PubMed   Mentions: 599     Fields:    Translation:AnimalsCells
    238. Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development. J Clin Invest. 2001 Feb; 107(3):295-304. Chung UI, Schipani E, McMahon AP, Kronenberg HM. PMID: 11160153; PMCID: PMC199199.
      View in: PubMed   Mentions: 141     Fields:    Translation:AnimalsCells
    239. Hedgehog signaling is required for pituitary gland development. Development. 2001 Feb; 128(3):377-86. Treier M, O'Connell S, Gleiberman A, Price J, Szeto DP, Burgess R, Chuang PT, McMahon AP, Rosenfeld MG. PMID: 11152636.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    240. Characterization of Pax-2 regulatory sequences that direct transgene expression in the Wolffian duct and its derivatives. Dev Biol. 2001 Jan 01; 229(1):128-40. Kuschert S, Rowitch DH, Haenig B, McMahon AP, Kispert A. PMID: 11133159.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    241. Sonic hedgehog regulates growth and morphogenesis of the tooth. Development. 2000 Nov; 127(22):4775-85. Dassule HR, Lewis P, Bei M, Maas R, McMahon AP. PMID: 11044393.
      View in: PubMed   Mentions: 351     Fields:    Translation:AnimalsCells
    242. Regulation of pancreas development by hedgehog signaling. Development. 2000 Nov; 127(22):4905-13. Hebrok M, Kim SK, St Jacques B, McMahon AP, Melton DA. PMID: 11044404.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansAnimalsCells
    243. Secreted molecules in metanephric induction. J Am Soc Nephrol. 2000 Nov; 11 Suppl 16:S116-9. Carroll TJ, McMahon AP. PMID: 11065341.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    244. Neural patterning: the role of Nkx genes in the ventral spinal cord. Genes Dev. 2000 Sep 15; 14(18):2261-4. McMahon AP. PMID: 10995382.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    245. Localization of 17beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase isoform expression in the developing mouse testis--androstenedione is the major androgen secreted by fetal/neonatal leydig cells. Endocrinology. 2000 Jul; 141(7):2631-7. O'Shaughnessy PJ, Baker PJ, Heikkilä M, Vainio S, McMahon AP. PMID: 10875268.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    246. Hedgehog signals regulate multiple aspects of gastrointestinal development. Development. 2000 Jun; 127(12):2763-72. Ramalho-Santos M, Melton DA, McMahon AP. PMID: 10821773.
      View in: PubMed   Mentions: 256     Fields:    Translation:HumansAnimals
    247. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development. 2000 Apr; 127(8):1671-9. Chai Y, Jiang X, Ito Y, Bringas P, Han J, Rowitch DH, Soriano P, McMahon AP, Sucov HM. PMID: 10725243.
      View in: PubMed   Mentions: 599     Fields:    Translation:Animals
    248. Fate of the mammalian cardiac neural crest. Development. 2000 Apr; 127(8):1607-16. Jiang X, Rowitch DH, Soriano P, McMahon AP, Sucov HM. PMID: 10725237.
      View in: PubMed   Mentions: 489     Fields:    Translation:Animals
    249. A model for anteroposterior patterning of the vertebrate limb based on sequential long- and short-range Shh signalling and Bmp signalling. Development. 2000 Apr; 127(7):1337-48. Drossopoulou G, Lewis KE, Sanz-Ezquerro JJ, Nikbakht N, McMahon AP, Hofmann C, Tickle C. PMID: 10704381.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    250. Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes Dev. 2000 Mar 15; 14(6):650-4. Brisken C, Heineman A, Chavarria T, Elenbaas B, Tan J, Dey SK, McMahon JA, McMahon AP, Weinberg RA. PMID: 10733525; PMCID: PMC316462.
      View in: PubMed   Mentions: 224     Fields:    Translation:AnimalsCells
    251. The organizer factors Chordin and Noggin are required for mouse forebrain development. Nature. 2000 Feb 10; 403(6770):658-61. Bachiller D, Klingensmith J, Kemp C, Belo JA, Anderson RM, May SR, McMahon JA, McMahon AP, Harland RM, Rossant J, De Robertis EM. PMID: 10688202.
      View in: PubMed   Mentions: 153     Fields:    Translation:Animals
    252. Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron. 2000 Feb; 25(2):317-29. Lu QR, Yuk D, Alberta JA, Zhu Z, Pawlitzky I, Chan J, McMahon AP, Stiles CD, Rowitch DH. PMID: 10719888.
      View in: PubMed   Mentions: 307     Fields:    Translation:AnimalsCells
    253. A local Wnt-3a signal is required for development of the mammalian hippocampus. Development. 2000 Feb; 127(3):457-67. Lee SM, Tole S, Grove E, McMahon AP. PMID: 10631167.
      View in: PubMed   Mentions: 222     Fields:    Translation:AnimalsCells
    254. Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways. Development. 2000 Feb; 127(3):543-8. Karp SJ, Schipani E, St-Jacques B, Hunzelman J, Kronenberg H, McMahon AP. PMID: 10631175.
      View in: PubMed   Mentions: 140     Fields:    Translation:AnimalsCells
    255. More surprises in the Hedgehog signaling pathway. Cell. 2000 Jan 21; 100(2):185-8. McMahon AP. PMID: 10660040.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    256. T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes Dev. 1999 Dec 15; 13(24):3185-90. Yamaguchi TP, Takada S, Yoshikawa Y, Wu N, McMahon AP. PMID: 10617567; PMCID: PMC317203.
      View in: PubMed   Mentions: 196     Fields:    Translation:AnimalsCells
    257. Pax-2 regulatory sequences that direct transgene expression in the developing neural plate and external granule cell layer of the cerebellum. Brain Res Dev Brain Res. 1999 Oct 20; 117(1):99-108. Rowitch DH, Kispert A, McMahon AP. PMID: 10536237.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    258. Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells. J Neurosci. 1999 Oct 15; 19(20):8954-65. Rowitch DH, S-Jacques B, Lee SM, Flax JD, Snyder EY, McMahon AP. PMID: 10516314; PMCID: PMC6782773.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    259. Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds. Nature. 1999 Oct 07; 401(6753):598-602. Zúñiga A, Haramis AP, McMahon AP, Zeller R. PMID: 10524628.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    260. Schwann Cell-Derived Desert Hedgehog Signals Nerve Sheath Formation. Ann N Y Acad Sci. 1999 Oct; 883(1):196-202. Mirsky R, Parmantier E, McMahon AP, Jessen KR. PMID: 29086927.
      View in: PubMed   Mentions: 2     Fields:    
    261. Schwann cell-derived desert hedgehog signals nerve sheath formation. Ann N Y Acad Sci. 1999 Sep 14; 883:196-202. Mirsky R, Parmantier E, McMahon AP, Jessen KR. PMID: 10586245.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    262. Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev. 1999 Aug 15; 13(16):2072-86. St-Jacques B, Hammerschmidt M, McMahon AP. PMID: 10465785; PMCID: PMC316949.
      View in: PubMed   Mentions: 644     Fields:    Translation:AnimalsCells
    263. Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths. Neuron. 1999 Aug; 23(4):713-24. Parmantier E, Lynn B, Lawson D, Turmaine M, Namini SS, Chakrabarti L, McMahon AP, Jessen KR, Mirsky R. PMID: 10482238.
      View in: PubMed   Mentions: 104     Fields:    Translation:AnimalsCells
    264. Noggin is a mesenchymally derived stimulator of hair-follicle induction. Nat Cell Biol. 1999 Jul; 1(3):158-64. Botchkarev VA, Botchkareva NV, Roth W, Nakamura M, Chen LH, Herzog W, Lindner G, McMahon JA, Peters C, Lauster R, McMahon AP, Paus R. PMID: 10559902.
      View in: PubMed   Mentions: 146     Fields:    Translation:Animals
    265. Cystic malformation of the posterior cerebellar vermis in transgenic mice that ectopically express Engrailed-1, a homeodomain transcription factor. Teratology. 1999 Jul; 60(1):22-8. Rowitch DH, Danielian PS, McMahon AP, Zec N. PMID: 10413335.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    266. Modulation of early but not later stages of programmed cell death in embryonic avian spinal cord by sonic hedgehog. Mol Cell Neurosci. 1999 May; 13(5):348-61. Oppenheim RW, Homma S, Marti E, Prevette D, Wang S, Yaginuma H, McMahon AP. PMID: 10356297.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    267. Negative feedback mechanisms and their roles during pattern formation. Cell. 1999 Apr 02; 97(1):13-6. Perrimon N, McMahon AP. PMID: 10199398.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    268. A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development. 1999 Mar; 126(6):1211-23. Yamaguchi TP, Bradley A, McMahon AP, Jones S. PMID: 10021340.
      View in: PubMed   Mentions: 395     Fields:    Translation:AnimalsCells
    269. Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein. Nature. 1999 Feb 18; 397(6720):617-21. Chuang PT, McMahon AP. PMID: 10050855.
      View in: PubMed   Mentions: 278     Fields:    Translation:AnimalsCells
    270. Female development in mammals is regulated by Wnt-4 signalling. Nature. 1999 Feb 04; 397(6718):405-9. Vainio S, Heikkilä M, Kispert A, Chin N, McMahon AP. PMID: 9989404.
      View in: PubMed   Mentions: 370     Fields:    Translation:AnimalsCells
    271. "Cre"-ating mouse mutants-a meeting review on conditional mouse genetics. Genes Dev. 1999 Jan 15; 13(2):142-5. Rossant J, McMahon A. PMID: 9925637.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    272. Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells. J Biol Chem. 1999 Jan 01; 274(1):129-34. Li L, Yuan H, Xie W, Mao J, Caruso AM, McMahon A, Sussman DJ, Wu D. PMID: 9867820.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    273. Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and -independent mechanisms. Development. 1999 Jan; 126(2):281-92. Epstein DJ, McMahon AP, Joyner AL. PMID: 9847242.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    274. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr Biol. 1998 Dec 03; 8(24):1323-6. Danielian PS, Muccino D, Rowitch DH, Michael SK, McMahon AP. PMID: 9843687.
      View in: PubMed   Mentions: 712     Fields:    Translation:AnimalsCells
    275. Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development. 1998 Nov; 125(21):4225-34. Kispert A, Vainio S, McMahon AP. PMID: 9753677.
      View in: PubMed   Mentions: 160     Fields:    Translation:AnimalsCells
    276. Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a. Nature. 1998 Oct 15; 395(6703):707-10. Parr BA, McMahon AP. PMID: 9790192.
      View in: PubMed   Mentions: 110     Fields:    Translation:Animals
    277. Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Dev Biol. 1998 Oct 15; 202(2):215-27. Dassule HR, McMahon AP. PMID: 9769173.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    278. The classical mouse mutant postaxial hemimelia results from a mutation in the Wnt 7a gene. Dev Biol. 1998 Oct 15; 202(2):228-34. Parr BA, Avery EJ, Cygan JA, McMahon AP. PMID: 9769174.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    279. Inhibitory action of BMPs on Pax1 expression and on shoulder girdle formation during limb development. Dev Dyn. 1998 Oct; 213(2):199-206. Hofmann C, Drossopoulou G, McMahon A, Balling R, Tickle C. PMID: 9786420.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    280. Sonic hedgehog signaling is essential for hair development. Curr Biol. 1998 Sep 24; 8(19):1058-68. St-Jacques B, Dassule HR, Karavanova I, Botchkarev VA, Li J, Danielian PS, McMahon JA, Lewis PM, Paus R, McMahon AP. PMID: 9768360.
      View in: PubMed   Mentions: 263     Fields:    Translation:AnimalsCells
    281. Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Curr Biol. 1998 Sep 24; 8(19):1083-6. Pepicelli CV, Lewis PM, McMahon AP. PMID: 9768363.
      View in: PubMed   Mentions: 222     Fields:    Translation:Animals
    282. Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling. Development. 1998 Aug; 125(16):3123-32. Yang Y, Guillot P, Boyd Y, Lyon MF, McMahon AP. PMID: 9671585.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    283. Identification of an evolutionarily conserved 110 base-pair cis-acting regulatory sequence that governs Wnt-1 expression in the murine neural plate. Development. 1998 Jul; 125(14):2735-46. Rowitch DH, Echelard Y, Danielian PS, Gellner K, Brenner S, McMahon AP. PMID: 9636087.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    284. FGF is an essential regulator of the fifth cell division in preimplantation mouse embryos. Dev Biol. 1998 Jun 01; 198(1):105-15. Chai N, Patel Y, Jacobson K, McMahon J, McMahon A, Rappolee DA. PMID: 9640334.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    285. Multistep signaling requirements for pituitary organogenesis in vivo. Genes Dev. 1998 Jun 01; 12(11):1691-704. Treier M, Gleiberman AS, O'Connell SM, Szeto DP, McMahon JA, McMahon AP, Rosenfeld MG. PMID: 9620855; PMCID: PMC316866.
      View in: PubMed   Mentions: 127     Fields:    Translation:AnimalsCells
    286. Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton. Science. 1998 May 29; 280(5368):1455-7. Brunet LJ, McMahon JA, McMahon AP, Harland RM. PMID: 9603738.
      View in: PubMed   Mentions: 222     Fields:    Translation:AnimalsCells
    287. Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev. 1998 May 15; 12(10):1438-52. McMahon JA, Takada S, Zimmerman LB, Fan CM, Harland RM, McMahon AP. PMID: 9585504; PMCID: PMC316831.
      View in: PubMed   Mentions: 238     Fields:    Translation:Animals
    288. The effect of pertussis toxin on zebrafish development: a possible role for inhibitory G-proteins in hedgehog signaling. Dev Biol. 1998 Feb 15; 194(2):166-71. Hammerschmidt M, McMahon AP. PMID: 9501021.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    289. Calbindin-D28k buffers intracellular calcium and promotes resistance to degeneration in PC12 cells. Brain Res Mol Brain Res. 1998 Feb; 54(1):56-63. McMahon A, Wong BS, Iacopino AM, Ng MC, Chi S, German DC. PMID: 9526044.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    290. A 5.5-kb enhancer is both necessary and sufficient for regulation of Wnt-1 transcription in vivo. Dev Biol. 1997 Dec 15; 192(2):300-9. Danielian PS, Echelard Y, Vassileva G, McMahon AP. PMID: 9441669.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    291. Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants. Development. 1997 Dec; 124(24):5021-32. Cygan JA, Johnson RL, McMahon AP. PMID: 9362463.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    292. Calbindin-D28k in nerve cell nuclei. Neuroscience. 1997 Dec; 81(3):735-43. German DC, Ng MC, Liang CL, McMahon A, Iacopino AM. PMID: 9316025.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    293. GDNF induces branching and increased cell proliferation in the ureter of the mouse. Dev Biol. 1997 Dec 01; 192(1):193-8. Pepicelli CV, Kispert A, Rowitch DH, McMahon AP. PMID: 9405108.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    294. Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb. Development. 1997 Nov; 124(21):4393-404. Yang Y, Drossopoulou G, Chuang PT, Duprez D, Marti E, Bumcrot D, Vargesson N, Clarke J, Niswander L, McMahon A, Tickle C. PMID: 9334287.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    295. Recent advances in hedgehog signalling. Trends Cell Biol. 1997 Nov; 7(11):442-6. Tabin CJ, McMahon AP. PMID: 17709003.
      View in: PubMed   Mentions: 12     Fields:    
    296. Wnt signalling required for expansion of neural crest and CNS progenitors. Nature. 1997 Oct 30; 389(6654):966-70. Ikeya M, Lee SM, Johnson JE, McMahon AP, Takada S. PMID: 9353119.
      View in: PubMed   Mentions: 212     Fields:    Translation:AnimalsCells
    297. Dopamine transporter mRNA levels are high in midbrain neurons vulnerable to MPTP. Neuroreport. 1997 Oct 20; 8(15):3327-31. Sanghera MK, Manaye K, McMahon A, Sonsalla PK, German DC. PMID: 9351666.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    298. A role for Indian hedgehog in extraembryonic endoderm differentiation in F9 cells and the early mouse embryo. Dev Biol. 1997 Jul 15; 187(2):298-310. Becker S, Wang ZJ, Massey H, Arauz A, Labosky P, Hammerschmidt M, St-Jacques B, Bumcrot D, McMahon A, Grabel L. PMID: 9242425.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    299. The zebrafish organizer requires chordino. Nature. 1997 Jun 26; 387(6636):862-3. Schulte-Merker S, Lee KJ, McMahon AP, Hammerschmidt M. PMID: 9202118.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
    300. Analysis of neural crest cell migration in Splotch mice using a neural crest-specific LacZ reporter. Dev Biol. 1997 May 15; 185(2):139-47. Serbedzija GN, McMahon AP. PMID: 9187079.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    301. Evidence that absence of Wnt-3a signaling promotes neuralization instead of paraxial mesoderm development in the mouse. Dev Biol. 1997 Mar 15; 183(2):234-42. Yoshikawa Y, Fujimori T, McMahon AP, Takada S. PMID: 9126297.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    302. Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development. 1997 Mar; 124(5):959-69. Lee SM, Danielian PS, Fritzsch B, McMahon AP. PMID: 9056772.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    303. Assignment of WNT7B to human chromosome band 22q13 by in situ hybridization. Cytogenet Cell Genet. 1997; 77(3-4):288-9. van Bokhoven H, Kissing J, Schepens M, van Beersum S, Simons A, Riegman P, McMahon JA, McMahon AP, Brunner HG. PMID: 9284940.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    304. Wnt5 is required for tail formation in the zebrafish embryo. Cold Spring Harb Symp Quant Biol. 1997; 62:227-34. Rauch GJ, Hammerschmidt M, Blader P, Schauerte HE, Strähle U, Ingham PW, McMahon AP, Haffter P. PMID: 9598355.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    305. Cell interactions in patterning the mammalian midbrain. Cold Spring Harb Symp Quant Biol. 1997; 62:535-44. Rowitch DH, Danielian PS, Lee SM, Echelard Y, McMahon AP. PMID: 9598387.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    306. The world according to hedgehog. Trends Genet. 1997 Jan; 13(1):14-21. Hammerschmidt M, Brook A, McMahon AP. PMID: 9009843.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimalsCells
    307. Genes from zebrafish screens. Nature. 1996 Dec 12; 384(6609):515-6. Holder N, McMahon A. PMID: 8955264.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    308. Hedgehogs in the clinic. Nat Med. 1996 Dec; 2(12):1308-10. McMahon AP, Chuang PT. PMID: 8946825.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    309. Calbindin-D28K in the nucleus of nerve growth factor-treated PC12 cells. Neuroreport. 1996 Nov 04; 7(15-17):2419-22. McMahon A, Lephart ED, Chi S, Lee M, Iacopino AM, German DC. PMID: 8981395.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    310. Cell death in the CNS of the Wnt-1 mutant mouse. J Neurobiol. 1996 Nov; 31(3):275-82. Serbedzija GN, Dickinson M, McMahon AP. PMID: 8910786.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    311. Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips. Development. 1996 Nov; 122(11):3627-37. Kispert A, Vainio S, Shen L, Rowitch DH, McMahon AP. PMID: 8951078.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    312. Early deletion of neuromeres in Wnt-1-/- mutant mice: evaluation by morphological and molecular markers. J Comp Neurol. 1996 Oct 14; 374(2):246-58. Mastick GS, Fan CM, Tessier-Lavigne M, Serbedzija GN, McMahon AP, Easter SS. PMID: 8906497.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    313. Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor. Genes Dev. 1996 Oct 01; 10(19):2452-61. Hammerschmidt M, Serbedzija GN, McMahon AP. PMID: 8843197.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    314. Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development. Nature. 1996 Sep 26; 383(6598):332-4. Danielian PS, McMahon AP. PMID: 8848044.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    315. Antagonizing cAMP-dependent protein kinase A in the dorsal CNS activates a conserved Sonic hedgehog signaling pathway. Development. 1996 Sep; 122(9):2885-94. Epstein DJ, Marti E, Scott MP, McMahon AP. PMID: 8787761.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    316. Early mouse development: lessons from gene targeting. Curr Opin Genet Dev. 1996 Aug; 6(4):439-44. St-Jacques B, McMahon AP. PMID: 8791525.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    317. Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2. Nature. 1996 May 16; 381(6579):238-41. Zhang J, Hagopian-Donaldson S, Serbedzija G, Elsemore J, Plehn-Dujowich D, McMahon AP, Flavell RA, Williams T. PMID: 8622766.
      View in: PubMed   Mentions: 183     Fields:    Translation:Animals
    318. Cloning and characterization of cDNAs for novel proteins with glutamic acid-proline dipeptide tandem repeats. Biochim Biophys Acta. 1996 May 02; 1306(2-3):147-52. Geertman R, McMahon A, Sabban EL. PMID: 8634331.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    319. Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. Genes Dev. 1996 Mar 15; 10(6):647-58. Hammerschmidt M, Bitgood MJ, McMahon AP. PMID: 8598293.
      View in: PubMed   Mentions: 95     Fields:    Translation:AnimalsCells
    320. Sertoli cell signaling by Desert hedgehog regulates the male germline. Curr Biol. 1996 Mar 01; 6(3):298-304. Bitgood MJ, Shen L, McMahon AP. PMID: 8805249.
      View in: PubMed   Mentions: 188     Fields:    Translation:AnimalsCells
    321. Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development. Genes Dev. 1996 Feb 01; 10(3):313-24. Greco TL, Takada S, Newhouse MM, McMahon JA, McMahon AP, Camper SA. PMID: 8595882.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    322. Induction of adrenal tyrosine hydroxylase mRNA by single immobilization stress occurs even after splanchnic transection and in the presence of cholinergic antagonists. J Neurochem. 1996 Jan; 66(1):138-46. Kvetnanský R, Nankova B, Hiremagalur B, Viskupic E, Vietor I, Rusnak M, McMahon A, Kopin IJ, Sabban EL. PMID: 8522945.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    323. Sonic hedgehog: making the gradient. Chem Biol. 1996 Jan; 3(1):13-6. Bumcrot DA, McMahon AP. PMID: 8807822.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    324. Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite. Genes Dev. 1995 Dec 01; 9(23):2911-22. Münsterberg AE, Kitajewski J, Bumcrot DA, McMahon AP, Lassar AB. PMID: 7498788.
      View in: PubMed   Mentions: 110     Fields:    Translation:AnimalsCells
    325. Induction of dopaminergic neuron phenotype in the midbrain by Sonic hedgehog protein. Nat Med. 1995 Nov; 1(11):1184-8. Wang MZ, Jin P, Bumcrot DA, Marigo V, McMahon AP, Wang EA, Woolf T, Pang K. PMID: 7584992.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    326. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol. 1995 Nov; 172(1):126-38. Bitgood MJ, McMahon AP. PMID: 7589793.
      View in: PubMed   Mentions: 335     Fields:    Translation:AnimalsCells
    327. Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties. Exp Cell Res. 1995 Oct; 220(2):363-73. Burrus LW, McMahon AP. PMID: 7556445.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    328. A single homeodomain binding site restricts spatial expression of Wnt-1 in the developing brain. Mech Dev. 1995 Sep; 53(1):87-96. Iler N, Rowitch DH, Echelard Y, McMahon AP, Abate-Shen C. PMID: 8555114.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    329. Development of midbrain and anterior hindbrain ocular motoneurons in normal and Wnt-1 knockout mice. J Neurobiol. 1995 Aug; 27(4):457-69. Fritzsch B, Nichols DH, Echelard Y, McMahon AP. PMID: 7561827.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    330. Distribution of Sonic hedgehog peptides in the developing chick and mouse embryo. Development. 1995 Aug; 121(8):2537-47. Martí E, Takada R, Bumcrot DA, Sasaki H, McMahon AP. PMID: 7671817.
      View in: PubMed   Mentions: 73     Fields:    Translation:Animals
    331. Dorsalization of the neural tube by the non-neural ectoderm. Development. 1995 Jul; 121(7):2099-106. Dickinson ME, Selleck MA, McMahon AP, Bronner-Fraser M. PMID: 7635055.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    332. Wnt expression patterns in chick embryo nervous system. Mech Dev. 1995 Jul; 52(1):9-25. Hollyday M, McMahon JA, McMahon AP. PMID: 7577679.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    333. Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1. Mech Dev. 1995 Jul; 52(1):3-8. Rowitch DH, McMahon AP. PMID: 7577673.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    334. Somite differentiation. Sonic signals somites. Curr Biol. 1995 Jun 01; 5(6):612-4. Bumcrot DA, McMahon AP. PMID: 7552169.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    335. Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants. Nature. 1995 May 25; 375(6529):322-5. Martí E, Bumcrot DA, Takada R, McMahon AP. PMID: 7753196.
      View in: PubMed   Mentions: 109     Fields:    Translation:AnimalsCells
    336. Proteolytic processing yields two secreted forms of sonic hedgehog. Mol Cell Biol. 1995 Apr; 15(4):2294-303. Bumcrot DA, Takada R, McMahon AP. PMID: 7891723; PMCID: PMC230457.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    337. Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature. 1995 Mar 23; 374(6520):350-3. Parr BA, McMahon AP. PMID: 7885472.
      View in: PubMed   Mentions: 129     Fields:    Translation:AnimalsCells
    338. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature. 1994 Dec 15; 372(6507):679-83. Stark K, Vainio S, Vassileva G, McMahon AP. PMID: 7990960.
      View in: PubMed   Mentions: 333     Fields:    Translation:AnimalsCells
    339. Mouse development. Winged-helix in axial patterning. Curr Biol. 1994 Oct 01; 4(10):903-6. McMahon AP. PMID: 7850424.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    340. Differential transformation of mammary epithelial cells by Wnt genes. Mol Cell Biol. 1994 Sep; 14(9):6278-86. Wong GT, Gavin BJ, McMahon AP. PMID: 8065359; PMCID: PMC359154.
      View in: PubMed   Mentions: 93     Fields:    Translation:AnimalsCells
    341. Wnt-1-dependent regulation of local E-cadherin and alpha N-catenin expression in the embryonic mouse brain. Development. 1994 Aug; 120(8):2225-34. Shimamura K, Hirano S, McMahon AP, Takeichi M. PMID: 7925023.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    342. Wnt genes and vertebrate development. Curr Opin Genet Dev. 1994 Aug; 4(4):523-8. Parr BA, McMahon AP. PMID: 7950319.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    343. Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS. Development. 1994 Aug; 120(8):2213-24. Echelard Y, Vassileva G, McMahon AP. PMID: 7925022.
      View in: PubMed   Mentions: 112     Fields:    Translation:AnimalsCells
    344. Experimental control of axial pattern in the chick blastoderm by local expression of Wnt and activin: the role of HNK-1 positive cells. Dev Biol. 1994 Aug; 164(2):513-27. Cooke J, Takada S, McMahon A. PMID: 7519156.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    345. Induction of tyrosine hydroxylase gene expression by a nonneuronal nonpituitary-mediated mechanism in immobilization stress. Proc Natl Acad Sci U S A. 1994 Jun 21; 91(13):5937-41. Nankova B, Kvetnanský R, McMahon A, Viskupic E, Hiremagalur B, Frankle G, Fukuhara K, Kopin IJ, Sabban EL. PMID: 7912437; PMCID: PMC44112.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    346. Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous system. Development. 1994 Jun; 120(6):1453-71. Dickinson ME, Krumlauf R, McMahon AP. PMID: 8050356.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    347. Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue. Cancer Res. 1994 May 15; 54(10):2615-21. Huguet EL, McMahon JA, McMahon AP, Bicknell R, Harris AL. PMID: 8168088.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    348. DNA affinity cleaving analysis of homeodomain-DNA interaction: identification of homeodomain consensus sites in genomic DNA. Proc Natl Acad Sci U S A. 1994 Jan 04; 91(1):118-22. Shang Z, Ebright YW, Iler N, Pendergrast PS, Echelard Y, McMahon AP, Ebright RH, Abate C. PMID: 7904065; PMCID: PMC42897.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    349. Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev. 1994 Jan; 8(2):174-89. Takada S, Stark KL, Shea MJ, Vassileva G, McMahon JA, McMahon AP. PMID: 8299937.
      View in: PubMed   Mentions: 234     Fields:    Translation:AnimalsCells
    350. The hedgehog gene family in Drosophila and vertebrate development. Dev Suppl. 1994; 43-51. Fietz MJ, Concordet JP, Barbosa R, Johnson R, Krauss S, McMahon AP, Tabin C, Ingham PW. PMID: 7579523.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    351. Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors. Neuron. 1994 Jan; 12(1):11-24. Zimmerman L, Parr B, Lendahl U, Cunningham M, McKay R, Gavin B, Mann J, Vassileva G, McMahon A. PMID: 8292356.
      View in: PubMed   Mentions: 225     Fields:    Translation:AnimalsCells
    352. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell. 1993 Dec 31; 75(7):1417-30. Echelard Y, Epstein DJ, St-Jacques B, Shen L, Mohler J, McMahon JA, McMahon AP. PMID: 7916661.
      View in: PubMed   Mentions: 597     Fields:    Translation:AnimalsCells
    353. Wnt family proteins are secreted and associated with the cell surface. Mol Biol Cell. 1993 Dec; 4(12):1267-75. Smolich BD, McMahon JA, McMahon AP, Papkoff J. PMID: 8167409; PMCID: PMC275763.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    354. Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development. 1993 Sep; 119(1):247-61. Parr BA, Shea MJ, Vassileva G, McMahon AP. PMID: 8275860.
      View in: PubMed   Mentions: 185     Fields:    Translation:Animals
    355. Cell signalling in induction and anterior-posterior patterning of the vertebrate central nervous system. Curr Opin Neurobiol. 1993 Feb; 3(1):4-7. McMahon AP. PMID: 8453288.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    356. Cloning developmentally regulated gene families. Methods Enzymol. 1993; 225:653-63. Gavin BJ, McMahon AP. PMID: 8231877.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    357. Factors influencing frequency production of transgenic mice. Methods Enzymol. 1993; 225:771-81. Mann JR, McMahon AP. PMID: 8231885.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    358. Regulation of expression of dopamine beta-hydroxylase in PC12 cells by glucocorticoids and cyclic AMP analogues. J Neurochem. 1992 Dec; 59(6):2040-7. McMahon A, Sabban EL. PMID: 1359011.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    359. The role of Wnt genes in vertebrate development. Curr Opin Genet Dev. 1992 Aug; 2(4):562-6. Dickinson ME, McMahon AP. PMID: 1388080.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    360. Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development. 1992 Jul; 115(3):737-44. Del Amo FF, Smith DE, Swiatek PJ, Gendron-Maguire M, Greenspan RJ, McMahon AP, Gridley T. PMID: 1425352.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    361. Regulation of tyrosine hydroxylase and dopamine beta-hydroxylase mRNA levels in rat adrenals by a single and repeated immobilization stress. J Neurochem. 1992 Jun; 58(6):2124-30. McMahon A, Kvetnanský R, Fukuhara K, Weise VK, Kopin IJ, Sabban EL. PMID: 1349344.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    362. The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell. 1992 May 15; 69(4):581-95. McMahon AP, Joyner AL, Bradley A, McMahon JA. PMID: 1534034.
      View in: PubMed   Mentions: 129     Fields:    Translation:AnimalsCells
    363. Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland. Mol Cell Biol. 1992 May; 12(5):2418-23. Gavin BJ, McMahon AP. PMID: 1373817; PMCID: PMC364414.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    364. Regulated expression of the tyrosine hydroxylase gene by membrane depolarization. Identification of the responsive element and possible second messengers. J Biol Chem. 1992 Apr 15; 267(11):7563-9. Kilbourne EJ, Nankova BB, Lewis EJ, McMahon A, Osaka H, Sabban DB, Sabban EL. PMID: 1348505.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    365. The Wnt family of cell signalling molecules in postimplantation development of the mouse. Ciba Found Symp. 1992; 165:199-212; discussion 212-8. McMahon AP, Gavin BJ, Parr B, Bradley A, McMahon JA. PMID: 1516469.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    366. Membrane depolarization by isotonic or hypertonic KCl: differential effects on mRNA levels of tyrosine hydroxylase and dopamine beta-hydroxylase mRNA in PC12 cells. J Neurosci Methods. 1991 Dec; 40(2-3):193-202. Kilbourne EJ, McMahon A, Sabban EL. PMID: 1686923.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    367. FGFR-4, a new member of the fibroblast growth factor receptor family, expressed in the definitive endoderm and skeletal muscle lineages of the mouse. Development. 1991 Oct; 113(2):641-51. Stark KL, McMahon JA, McMahon AP. PMID: 1723680.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    368. Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis. Development. 1991 Apr; 111(4):1045-55. Christian JL, McMahon JA, McMahon AP, Moon RT. PMID: 1879349.
      View in: PubMed   Mentions: 78     Fields:    Translation:Animals
    369. Isolation of cDNAs partially encoding four Xenopus Wnt-1/int-1-related proteins and characterization of their transient expression during embryonic development. Dev Biol. 1991 Feb; 143(2):230-4. Christian JL, Gavin BJ, McMahon AP, Moon RT. PMID: 1991549.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    370. A new nomenclature for int-1 and related genes: the Wnt gene family. Cell. 1991 Jan 25; 64(2):231. Nusse R, Brown A, Papkoff J, Scambler P, Shackleford G, McMahon A, Moon R, Varmus H. PMID: 1846319.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    371. Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 1990 Dec; 4(12B):2319-32. Gavin BJ, McMahon JA, McMahon AP. PMID: 2279700.
      View in: PubMed   Mentions: 83     Fields:    Translation:AnimalsCells
    372. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell. 1990 Sep 21; 62(6):1073-85. McMahon AP, Bradley A. PMID: 2205396.
      View in: PubMed   Mentions: 418     Fields:    Translation:AnimalsCells
    373. Generation of diversity in nonerythroid spectrins. Multiple polypeptides are predicted by sequence analysis of cDNAs encompassing the coding region of human nonerythroid alpha-spectrin. J Biol Chem. 1990 Mar 15; 265(8):4427-33. Moon RT, McMahon AP. PMID: 2307671.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    374. Rat dopamine beta-hydroxylase: molecular cloning and characterization of the cDNA and regulation of the mRNA by reserpine. J Neurosci Res. 1990 Mar; 25(3):395-404. McMahon A, Geertman R, Sabban EL. PMID: 2325165.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    375. Developmental expression of the putative transcription factor Egr-1 suggests that Egr-1 and c-fos are coregulated in some tissues. Development. 1990 Feb; 108(2):281-7. McMahon AP, Champion JE, McMahon JA, Sukhatme VP. PMID: 2351070.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    376. Effect of compounds which disrupt proton gradients on secretion of neurosecretory proteins from PC12 pheochromocytoma cells. Neuroscience. 1990; 38(2):561-70. Sabban EL, Schwartz J, McMahon A. PMID: 2175857.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    377. Nucleotide sequence, chromosomal localization and developmental expression of the mouse int-1-related gene. Development. 1989 Nov; 107(3):643-50. McMahon JA, McMahon AP. PMID: 2693041.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    378. Endoglycosidase H susceptibility of secreted and intracellular forms of dopamine beta-hydroxylase. Biochem Int. 1989 Oct; 19(4):769-75. Sabban EL, McMahon A, Kuhn LJ. PMID: 2515859.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    379. Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis. Cell. 1989 Sep 22; 58(6):1075-84. McMahon AP, Moon RT. PMID: 2673541.
      View in: PubMed   Mentions: 142     Fields:    Translation:AnimalsCells
    380. Expression pattern of the FGF-related proto-oncogene int-2 suggests multiple roles in fetal development. Development. 1989 Jan; 105(1):131-6. Wilkinson DG, Bhatt S, McMahon AP. PMID: 2680421.
      View in: PubMed   Mentions: 51     Fields:    Translation:Animals
    381. int-1--a proto-oncogene involved in cell signalling. Development. 1989; 107 Suppl:161-7. McMahon AP, Moon RT. PMID: 2534596.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    382. Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse. EMBO J. 1988 Mar; 7(3):691-5. Wilkinson DG, Peters G, Dickson C, McMahon AP. PMID: 3293998; PMCID: PMC454374.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    383. Effects of ionizing radiation and pretreatment with [D-Leu6,des-Gly10] luteinizing hormone-releasing hormone ethylamide on developing rat ovarian follicles. Cancer Res. 1987 Oct 01; 47(19):5005-8. Jarrell J, YoungLai EV, McMahon A, Barr R, O'Connell G, Belbeck L. PMID: 3113726.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    384. Structure and evolution of a non-erythroid spectrin, human alpha-fodrin. Biochem Soc Trans. 1987 Oct; 15(5):804-7. McMahon AP, Moon RT. PMID: 3691949.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    385. Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo. Cell. 1987 Jul 03; 50(1):79-88. Wilkinson DG, Bailes JA, McMahon AP. PMID: 3594565.
      View in: PubMed   Mentions: 117     Fields:    Translation:AnimalsCells
    386. Ovarian toxicity of cyclophosphamide alone and in combination with ovarian irradiation in the rat. Cancer Res. 1987 May 01; 47(9):2340-3. Jarrell J, Lai EV, Barr R, McMahon A, Belbeck L, O'Connell G. PMID: 3105875.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    387. A molecular analysis of mouse development from 8 to 10 days post coitum detects changes only in embryonic globin expression. Development. 1987 Apr; 99(4):493-500. Wilkinson DG, Bailes JA, Champion JE, McMahon AP. PMID: 2444404.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    388. cDNA cloning, sequencing and chromosome mapping of a non-erythroid spectrin, human alpha-fodrin. Differentiation. 1987; 34(1):68-78. McMahon AP, Giebelhaus DH, Champion JE, Bailes JA, Lacey S, Carritt B, Henchman SK, Moon RT. PMID: 3038643.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    389. An analysis of the effects of increasing doses of ionizing radiation to the exteriorized rat ovary on follicular development, atresia, and serum gonadotropin levels. Am J Obstet Gynecol. 1986 Feb; 154(2):306-9. Jarrell J, YoungLai EV, Barr R, O'Connell G, Belbeck L, McMahon A. PMID: 3080889.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    390. Introduction of cloned DNA into sea urchin egg cytoplasm: replication and persistence during embryogenesis. Dev Biol. 1985 Apr; 108(2):420-30. McMahon AP, Flytzanis CN, Hough-Evans BR, Katula KS, Britten RJ, Davidson EH. PMID: 3000854.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    391. Persistence and integration of cloned DNA in postembryonic sea urchins. Dev Biol. 1985 Apr; 108(2):431-42. Flytzanis CN, McMahon AP, Hough-Evans BR, Katula KS, Britten RJ, Davidson EH. PMID: 3000855.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    392. Inducible expression of a cloned heat shock fusion gene in sea urchin embryos. Proc Natl Acad Sci U S A. 1984 Dec; 81(23):7490-4. McMahon AP, Novak TJ, Britten RJ, Davidson EH. PMID: 6594699; PMCID: PMC392172.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    393. Oocyte specific regulation of PGK-1 isozyme activity in female germ cells of the mouse. Genet Res. 1983 Aug; 42(1):77-89. McMahon A. PMID: 6628991.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    394. X-chromosome inactivation mosaicism in the three germ layers and the germ line of the mouse embryo. J Embryol Exp Morphol. 1983 Apr; 74:207-20. McMahon A, Fosten M, Monk M. PMID: 6886595.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    395. X-chromosome activity in female mouse embryos heterozygous for Pgk-1 and Searle's translocation, T(X; 16) 16H. Genet Res. 1983 Feb; 41(1):69-83. McMahon A, Monk M. PMID: 6840549.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    396. Random X-chromosome inactivation in female primordial germ cells in the mouse. J Embryol Exp Morphol. 1981 Aug; 64:251-8. McMahon A, Fosten M, Monk M. PMID: 7310304.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    With one click, see people who:

    Mentor Faculty

    Run Clinical Trials

    See more options in the Advanced Search tab

    Andrew's Networks
    Concepts (1098)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (36)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

    This site is running Profiles RNS version UCSF-v3.1.0-3-g1ef1264b on PROFILES-PWEB04. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.