Andrew P. McMahon, PhD

Title(s)W.M. Keck Provost and University Professor of Stem Cell Biology and Regenerative Medicine, Biological Sciences and Quantitative and Computational Biology
SchoolKeck School of Medicine of Usc
AddressBCC 312 1425 San Pablo Street
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 442 3056
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    Other Positions
    Title(s)Chair of Stem Cell Biology and Regenerative Medicine

    Title(s)Director, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC


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    Professor Andrew (Andy) McMahon is the Chair of the Department of Stem Cell Biology and Regenerative Medicine and Director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at the Keck School of Medicine of the University of Southern California (USC). McMahon joined USC from Harvard University in 2012 as the W.M. Keck Provost Professor of Stem Cell Biology and Regenerative Medicine, and Biological Sciences, and founding chair of the Department of Stem Cell Biology and Regenerative Medicine.

    McMahon is a leader in the field of developmental biology. McMahon’s research has provided fundamental insights into the cell interactions driving assembly of multiple organ systems, including the central nervous system, skeleton and kidney. McMahon’s research has identified diverse mechanisms regulating organ development, tissue repair and cancer. Current research focuses on development, injury and repair of the mammalian kidney, to model and treat kidney disease.

    McMahon received his bachelor's degree from Oxford University and his PhD from University College London. McMahon completed his postdoctoral research at the California Institute of Technology, then moved to London to start his independent research laboratory in 1984. In 1988, McMahon took up a position as assistant member at the Roche Institute for Molecular Biology, becoming full member and chair of the department in 1992. In 1993, McMahon became a professor of Molecular and Cellular Biology in the Faculty of Arts and Sciences at Harvard University. In a 19-year career at Harvard, McMahon was the Frank B. Baird Jr., Professor of Science, chair of the Department of Cell and Developmental Biology, a founding faculty of the Department of Stem Cells and Regenerative Biology, and principal investigator of the Harvard Stem Cell Institute.

    McMahon is an elected fellow of the National Academy of Sciences, the American Association for the Advancement of Science, the American Academy of Arts and Sciences, the European Molecular Biology Organization and the Royal Society.

    Collapse Research 
    Collapse Research Activities and Funding
    Sexual dimorphism in the mammalian kidney
    NIH R01DK126925Sep 17, 2020 - May 31, 2025
    Role: Principal Investigator
    Single-cell analysis to promote kidney repair
    NIH UC2DK126024Sep 1, 2020 - May 31, 2025
    Role: Co-Principal Investigator
    Mapping protein communication between organs in homeostasis and disease
    NIH R01DK121409Sep 25, 2018 - Jun 30, 2023
    Role: Co-Principal Investigator
    Epigenetic mechanisms underlying the failure of hair cell regeneration in mammals
    NIH R01DC015829Jul 1, 2018 - Jun 30, 2023
    Role: Co-Principal Investigator
    Establishing Mechanisms of Human Proximal Tubule Regeneration in an Engineered Organ on Chip Platform
    NIH R21EB025534Sep 23, 2017 - Jul 31, 2021
    Role: Co-Principal Investigator
    Four-dimensional Modeling of Mouse and Human Nephrogenesis.
    NIH U01DK110792Sep 15, 2016 - May 31, 2021
    Role: Principal Investigator
    Lineage reprogramming for hearing loss: development of drug screening and gene therapy approaches
    NIH R01DC015530Jul 1, 2016 - Jun 30, 2021
    Role: Co-Principal Investigator
    The USC (Re)Building the Kidney Coordinating Center
    NIH U01DK107350Sep 23, 2015 - Aug 31, 2021
    Role: Co-Principal Investigator
    GUDMAP2 - Production of Mouse Strains for Gene Anatomy of the Lower Urinary Tract
    NIH U01DK094526Sep 30, 2011 - Mar 31, 2017
    Role: Principal Investigator
    Kidney molecular atlas project
    NIH U01DK070181Sep 30, 2004 - Jul 31, 2012
    Role: Principal Investigator
    Developmental Regulation of Bone Morphogenesis
    NIH P01DK056246Aug 20, 1999 - May 31, 2016
    Role: Co-Principal Investigator
    Cell Interactions in Development of the Mammalian Kidney
    NIH R01DK054364Sep 1, 1998 - Dec 31, 2022
    Role: Principal Investigator
    Cell Interactions in Development of the Mammalian Kidney
    NIH R37DK054364Sep 1, 1998 - Jan 14, 2019
    Role: Principal Investigator
    CONFERENCE ON VERTEBRATE DEVELOPMENT
    NIH R13HD036196Mar 1, 1998 - Feb 28, 1999
    Role: Principal Investigator
    Regulation of polarity by Sonic hedgehog morphogen signaling
    NIH R01NS033642Dec 1, 1994 - Jul 31, 2018
    Role: Principal Investigator
    Regulation of CNS and Limb Polarity by Sonic Hedgehog
    NIH R37NS033642Dec 1, 1994 - Sep 14, 2012
    Role: Principal Investigator
    ACTIVATION OF A PATTERNING SIGNAL IN THE CNS
    NIH R01NS032691Apr 1, 1994 - Mar 31, 1998
    Role: Principal Investigator
    PATTERN REGULATION IN THE VERTEBRATE CNS
    NIH R01HD030249Dec 1, 1993 - Nov 30, 2003
    Role: Principal Investigator

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    Collapse Featured Content 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Spatial transcriptomics defines injury-specific microenvironments in the adult mouse kidney and novel cellular interactions in regeneration and disease. bioRxiv. 2023 Nov 22. Polonsky M, Gerhardt LMS, Yun J, Koppitch K, Colón KL, Amrhein H, Zheng S, Yuan GC, Thomson M, Cai L, McMahon AP. PMID: 38045285; PMCID: PMC10690238.
      View in: PubMed   Mentions:
    2. Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney. Dev Cell. 2023 11 06; 58(21):2338-2358.e5. Xiong L, Liu J, Han SY, Koppitch K, Guo JJ, Rommelfanger M, Miao Z, Gao F, Hallgrimsdottir IB, Pachter L, Kim J, MacLean AL, McMahon AP. PMID: 37673062; PMCID: PMC10873092.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    3. Canonical Wnt transcriptional complexes are essential for induction of nephrogenesis but not maintenance or proliferation of nephron progenitors. bioRxiv. 2023 Aug 21. Bugacov H, Der B, Kim S, Lindström NO, McMahon AP. PMID: 37662369; PMCID: PMC10473675.
      View in: PubMed   Mentions:
    4. User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium. APL Bioeng. 2023 Sep; 7(3):036106. Khalil NN, Petersen AP, Song CJ, Chen Y, Takamoto K, Kellogg AC, Chen EZ, McMahon AP, McCain ML. PMID: 37584027; PMCID: PMC10424157.
      View in: PubMed   Mentions: 1  
    5. Direct androgen receptor regulation of sexually dimorphic gene expression in the mammalian kidney. bioRxiv. 2023 May 25. Xiong L, Liu J, Han SY, Koppitch K, Guo JJ, Rommelfanger M, Gao F, Hallgrimsdottir IB, Pachter L, Kim J, MacLean AL, McMahon AP. PMID: 37205355; PMCID: PMC10187285.
      View in: PubMed   Mentions:
    6. Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids. bioRxiv. 2023 May 25. Huang B, Zeng Z, Li H, Li Z, Chen X, Guo J, Zhang CC, Schreiber ME, Vonk AC, Xiang T, Patel T, Li Y, Parvez RK, Der B, Chen JH, Liu Z, Thornton ME, Grubbs BH, Diao Y, Dou Y, Gnedeva K, Lindström NO, Ying Q, Pastor-Soler NM, Fei T, Hallows KR, McMahon AP, Li Z. PMID: 37293038; PMCID: PMC10245960.
      View in: PubMed   Mentions:
    7. Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development. bioRxiv. 2023 May 17. Kim S, Koppitch K, Parvez RK, Guo J, Achieng M, Schnell J, Lindström NO, McMahon AP. PMID: 37293066; PMCID: PMC10245679.
      View in: PubMed   Mentions:
    8. Proximal tubule responses to injury: interrogation by single-cell transcriptomics. Curr Opin Nephrol Hypertens. 2023 07 01; 32(4):352-358. Cippà PE, McMahon AP. PMID: 37074682; PMCID: PMC10330172.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Lineage Tracing and Single-Nucleus Multiomics Reveal Novel Features of Adaptive and Maladaptive Repair after Acute Kidney Injury. J Am Soc Nephrol. 2023 04 01; 34(4):554-571. Gerhardt LMS, Koppitch K, van Gestel J, Guo J, Cho S, Wu H, Kirita Y, Humphreys BD, McMahon AP. PMID: 36735940; PMCID: PMC10103206.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    10. Identifying Common Molecular Mechanisms in Experimental and Human Acute Kidney Injury. Semin Nephrol. 2022 05; 42(3):151286. Gerhardt LMS, McMahon AP. PMID: 36402654.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    11. Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages. Cell Rep. 2022 09 06; 40(10):111315. Hojo H, Saito T, He X, Guo Q, Onodera S, Azuma T, Koebis M, Nakao K, Aiba A, Seki M, Suzuki Y, Okada H, Tanaka S, Chung UI, McMahon AP, Ohba S. PMID: 36070691; PMCID: PMC9510047.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    12. A genetic model for in vivo proximity labelling of the mammalian secretome. Open Biol. 2022 08; 12(8):220149. Yang R, Meyer AS, Droujinine IA, Udeshi ND, Hu Y, Guo J, McMahon JA, Carey DK, Xu C, Fang Q, Sha J, Qin S, Rocco D, Wohlschlegel J, Ting AY, Carr SA, Perrimon N, McMahon AP. PMID: 35946312; PMCID: PMC9364151.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    13. A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery. Cell Stem Cell. 2022 07 07; 29(7):1083-1101.e7. Tran T, Song CJ, Nguyen T, Cheng SY, McMahon JA, Yang R, Guo Q, Der B, Lindström NO, Lin DC, McMahon AP. PMID: 35803227.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    14. Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing. Proc Natl Acad Sci U S A. 2022 06 21; 119(25):e2203179119. Xu J, Liu Y, Li H, Tarashansky AJ, Kalicki CH, Hung RJ, Hu Y, Comjean A, Kolluru SS, Wang B, Quake SR, Luo L, McMahon AP, Dow JAT, Perrimon N. PMID: 35696569; PMCID: PMC9231607.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    15. Kidney repair and regeneration: perspectives of the NIDDK (Re)Building a Kidney consortium. Kidney Int. 2022 05; 101(5):845-853. Naved BA, Bonventre JV, Hubbell JA, Hukriede NA, Humphreys BD, Kesselman C, Valerius MT, McMahon AP, Shankland SJ, Wertheim JA, White MJV, de Caestecker MP, Drummond IA. PMID: 35276204; PMCID: PMC9045003.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    16. Repairing the blood-brain barrier. Science. 2022 02 18; 375(6582):715-716. McMahon AP, Ichida JK. PMID: 35175806.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    17. Multi-omic approaches to acute kidney injury and repair. Curr Opin Biomed Eng. 2021 Dec; 20. Gerhardt LMS, McMahon AP. PMID: 35005326; PMCID: PMC8740908.
      View in: PubMed   Mentions: 5  
    18. Spatial transcriptional mapping of the human nephrogenic program. Dev Cell. 2021 08 23; 56(16):2381-2398.e6. Lindström NO, Sealfon R, Chen X, Parvez RK, Ransick A, De Sena Brandine G, Guo J, Hill B, Tran T, Kim AD, Zhou J, Tadych A, Watters A, Wong A, Lovero E, Grubbs BH, Thornton ME, McMahon JA, Smith AD, Ruffins SW, Armit C, Troyanskaya OG, McMahon AP. PMID: 34428401; PMCID: PMC8396064.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    19. Multi-omics integration in the age of million single-cell data. Nat Rev Nephrol. 2021 11; 17(11):710-724. Miao Z, Humphreys BD, McMahon AP, Kim J. PMID: 34417589; PMCID: PMC9191639.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    20. Single-nuclear transcriptomics reveals diversity of proximal tubule cell states in a dynamic response to acute kidney injury. Proc Natl Acad Sci U S A. 2021 07 06; 118(27). Gerhardt LMS, Liu J, Koppitch K, Cippà PE, McMahon AP. PMID: 34183416; PMCID: PMC8271768.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    21. Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors. Nat Commun. 2021 06 15; 12(1):3641. Zeng Z, Huang B, Parvez RK, Li Y, Chen J, Vonk AC, Thornton ME, Patel T, Rutledge EA, Kim AD, Yu J, Grubbs BH, McMahon JA, Pastor-Soler NM, Hallows KR, McMahon AP, Li Z. PMID: 34131121; PMCID: PMC8206157.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    22. Correction: A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells. Elife. 2021 Apr 29; 10. Guo Q, Kim AD, Li B, Ransick A, Bugacov H, Chen X, Lindström NO, Brown A, Oxburgh L, Ren B, McMahon AP. PMID: 33913807; PMCID: PMC8084526.
      View in: PubMed   Mentions:    Fields:    
    23. Proteomics of protein trafficking by in vivo tissue-specific labeling. Nat Commun. 2021 04 22; 12(1):2382. Droujinine IA, Meyer AS, Wang D, Udeshi ND, Hu Y, Rocco D, McMahon JA, Yang R, Guo J, Mu L, Carey DK, Svinkina T, Zeng R, Branon T, Tabatabai A, Bosch JA, Asara JM, Ting AY, Carr SA, McMahon AP, Perrimon N. PMID: 33888706; PMCID: PMC8062696.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    24. A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells. Elife. 2021 02 15; 10. Guo Q, Kim A, Li B, Ransick A, Bugacov H, Chen X, Lindström N, Brown A, Oxburgh L, Ren B, McMahon AP. PMID: 33587034; PMCID: PMC7924951.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    25. Author Correction: Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality. Nat Metab. 2020 09; 2(9):989. Legouis D, Ricksten SE, Faivre A, Verissimo T, Gariani K, Verney C, Galichon P, Berchtold L, Feraille E, Fernandez M, Placier S, Koppitch K, Hertig A, Martin PY, Naesens M, Pugin J, McMahon AP, Cippà PE, de Seigneux S. PMID: 32873966.
      View in: PubMed   Mentions: 1     Fields:    
    26. Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality. Nat Metab. 2020 08; 2(8):732-743. Legouis D, Ricksten SE, Faivre A, Verissimo T, Gariani K, Verney C, Galichon P, Berchtold L, Feraille E, Fernandez M, Placier S, Koppitch K, Hertig A, Martin PY, Naesens M, Pugin J, McMahon AP, Cippà PE, de Seigneux S. PMID: 32694833.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    27. A novel distal convoluted tubule-specific Cre-recombinase driven by the NaCl cotransporter gene. Am J Physiol Renal Physiol. 2020 09 01; 319(3):F423-F435. Cornelius RJ, Sharma A, Su XT, Guo JJ, McMahon JA, Ellison DH, McMahon AP, McCormick JA. PMID: 32657158; PMCID: PMC7509282.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    28. Mutational analysis of genes with ureteric progenitor cell-specific expression in branching morphogenesis of the mouse kidney. Dev Dyn. 2020 06; 249(6):765-774. Rutledge EA, McMahon AP. PMID: 32017326; PMCID: PMC7679181.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    29. Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury. J Am Soc Nephrol. 2020 04; 31(4):701-715. Liu J, Kumar S, Heinzel A, Gao M, Guo J, Alvarado GF, Reindl-Schwaighofer R, Krautzberger AM, Cippà PE, McMahon J, Oberbauer R, McMahon AP. PMID: 32034106; PMCID: PMC7191932.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    30. Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system. Dev Biol. 2020 02 15; 458(2):164-176. Rutledge EA, Lindström NO, Michos O, McMahon AP. PMID: 31734175; PMCID: PMC6995766.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    31. Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney. Dev Cell. 2019 11 04; 51(3):399-413.e7. Ransick A, Lindström NO, Liu J, Zhu Q, Guo JJ, Alvarado GF, Kim AD, Black HG, Kim J, McMahon AP. PMID: 31689386; PMCID: PMC6948019.
      View in: PubMed   Mentions: 144     Fields:    Translation:AnimalsCells
    32. Cellular Recruitment by Podocyte-Derived Pro-migratory Factors in Assembly of the Human Renal Filter. iScience. 2019 Oct 25; 20:402-414. Kim AD, Lake BB, Chen S, Wu Y, Guo J, Parvez RK, Tran T, Thornton ME, Grubbs B, McMahon JA, Zhang K, McMahon AP. PMID: 31622881; PMCID: PMC6817668.
      View in: PubMed   Mentions: 6  
    33. In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes. Dev Cell. 2019 07 01; 50(1):102-116.e6. Tran T, Lindström NO, Ransick A, De Sena Brandine G, Guo Q, Kim AD, Der B, Peti-Peterdi J, Smith AD, Thornton M, Grubbs B, McMahon JA, McMahon AP. PMID: 31265809; PMCID: PMC6684316.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    34. Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Dev Biol. 2019 10 15; 454(2):156-169. Rutledge EA, Parvez RK, Short KM, Smyth IM, McMahon AP. PMID: 31242448; PMCID: PMC6726516.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    35. A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation. Nat Commun. 2019 03 11; 10(1):1157. Cippà PE, Liu J, Sun B, Kumar S, Naesens M, McMahon AP. PMID: 30858375; PMCID: PMC6411919.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    36. Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback. Nat Commun. 2019 01 16; 10(1):239. Menshykau D, Michos O, Lang C, Conrad L, McMahon AP, Iber D. PMID: 30651543; PMCID: PMC6484223.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    37. Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment. Elife. 2018 12 05; 7. O'Brien LL, Combes AN, Short KM, Lindström NO, Whitney PH, Cullen-McEwen LA, Ju A, Abdelhalim A, Michos O, Bertram JF, Smyth IM, Little MH, McMahon AP. PMID: 30516471; PMCID: PMC6281319.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    38. Transcriptional trajectories of human kidney injury progression. JCI Insight. 2018 11 15; 3(22). Cippà PE, Sun B, Liu J, Chen L, Naesens M, McMahon AP. PMID: 30429361; PMCID: PMC6302941.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    39. Single-Cell RNA Sequencing of the Adult Mouse Kidney: From Molecular Cataloging of Cell Types to Disease-Associated Predictions. Am J Kidney Dis. 2019 01; 73(1):140-142. Lindström NO, De Sena Brandine G, Ransick A, McMahon AP. PMID: 30241960; PMCID: PMC6480390.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    40. Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through Cdk6 expression. Development. 2018 08 20; 145(17). Hasenpusch-Theil K, West S, Kelman A, Kozic Z, Horrocks S, McMahon AP, Price DJ, Mason JO, Theil T. PMID: 30093555; PMCID: PMC6141774.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    41. A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells. Stem Cell Reports. 2018 08 14; 11(2):470-484. Przepiorski A, Sander V, Tran T, Hollywood JA, Sorrenson B, Shih JH, Wolvetang EJ, McMahon AP, Holm TM, Davidson AJ. PMID: 30033089; PMCID: PMC6092837.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    42. Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis. Dev Cell. 2018 06 04; 45(5):651-660.e4. Lindström NO, De Sena Brandine G, Tran T, Ransick A, Suh G, Guo J, Kim AD, Parvez RK, Ruffins SW, Rutledge EA, Thornton ME, Grubbs B, McMahon JA, Smith AD, McMahon AP. PMID: 29870722; PMCID: PMC6510587.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    43. Disparate levels of beta-catenin activity determine nephron progenitor cell fate. Dev Biol. 2018 08 01; 440(1):13-21. Ramalingam H, Fessler AR, Das A, Valerius MT, Basta J, Robbins L, Brown AC, Oxburgh L, McMahon AP, Rauchman M, Carroll TJ. PMID: 29705331; PMCID: PMC5988999.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    44. Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions. PLoS Genet. 2018 04; 14(4):e1007346. Tan Z, Niu B, Tsang KY, Melhado IG, Ohba S, He X, Huang Y, Wang C, McMahon AP, Jauch R, Chan D, Zhang MQ, Cheah KSE. PMID: 29659575; PMCID: PMC5919691.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    45. Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney. J Am Soc Nephrol. 2018 03; 29(3):806-824. Lindström NO, Guo J, Kim AD, Tran T, Guo Q, De Sena Brandine G, Ransick A, Parvez RK, Thornton ME, Baskin L, Grubbs B, McMahon JA, Smith AD, McMahon AP. PMID: 29449449; PMCID: PMC5827607.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    46. Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning. J Am Soc Nephrol. 2018 03; 29(3):825-840. Lindström NO, Tran T, Guo J, Rutledge E, Parvez RK, Thornton ME, Grubbs B, McMahon JA, McMahon AP. PMID: 29449451; PMCID: PMC5827611.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    47. Conserved and Divergent Features of Human and Mouse Kidney Organogenesis. J Am Soc Nephrol. 2018 03; 29(3):785-805. Lindström NO, McMahon JA, Guo J, Tran T, Guo Q, Rutledge E, Parvez RK, Saribekyan G, Schuler RE, Liao C, Kim AD, Abdelhalim A, Ruffins SW, Thornton ME, Baskin L, Grubbs B, Kesselman C, McMahon AP. PMID: 29449453; PMCID: PMC5827606.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimals
    48. Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies. PLoS Genet. 2018 01; 14(1):e1007181. O'Brien LL, Guo Q, Bahrami-Samani E, Park JS, Hasso SM, Lee YJ, Fang A, Kim AD, Guo J, Hong TM, Peterson KA, Lozanoff S, Raviram R, Ren B, Fogelgren B, Smith AD, Valouev A, McMahon AP. PMID: 29377931; PMCID: PMC5805373.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    49. Development of the Human Fetal Kidney from Mid to Late Gestation in Male and Female Infants. EBioMedicine. 2018 Jan; 27:275-283. Ryan D, Sutherland MR, Flores TJ, Kent AL, Dahlstrom JE, Puelles VG, Bertram JF, McMahon AP, Little MH, Moore L, Black MJ. PMID: 29329932; PMCID: PMC5828465.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    50. An immunohistochemical identification key for cell types in adult mouse prostatic and urethral tissue sections. PLoS One. 2017; 12(11):e0188413. Wegner KA, Cadena MT, Trevena R, Turco AE, Gottschalk A, Halberg RB, Guo J, McMahon JA, McMahon AP, Vezina CM. PMID: 29145476; PMCID: PMC5690684.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
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    188. Neural crest origins of the neck and shoulder. Nature. 2005 Jul 21; 436(7049):347-55. Matsuoka T, Ahlberg PE, Kessaris N, Iannarelli P, Dennehy U, Richardson WD, McMahon AP, Koentges G. PMID: 16034409; PMCID: PMC1352163.
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    190. Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development. Development. 2005 Jun; 132(12):2809-23. Kobayashi A, Kwan KM, Carroll TJ, McMahon AP, Mendelsohn CL, Behringer RR. PMID: 15930111.
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    191. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005 May; 8(5):751-64. Glass DA, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G. PMID: 15866165.
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    192. Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Dev Cell. 2005 Feb; 8(2):229-39. Basson MA, Akbulut S, Watson-Johnson J, Simon R, Carroll TJ, Shakya R, Gross I, Martin GR, Lufkin T, McMahon AP, Wilson PD, Costantini FD, Mason IJ, Licht JD. PMID: 15691764.
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    193. Mouse brain organization revealed through direct genome-scale TF expression analysis. Science. 2004 Dec 24; 306(5705):2255-7. Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q. PMID: 15618518.
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    194. Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1. Development. 2005 Jan; 132(1):143-54. Jeong J, McMahon AP. PMID: 15576403.
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    195. Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand. Development. 2005 Jan; 132(1):133-42. Tian H, Jeong J, Harfe BD, Tabin CJ, McMahon AP. PMID: 15576405.
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    196. Recent genetic studies of mouse kidney development. Curr Opin Genet Dev. 2004 Oct; 14(5):550-7. Yu J, McMahon AP, Valerius MT. PMID: 15380247.
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    197. Temporal requirement for hedgehog signaling in ventral telencephalic patterning. Development. 2004 Oct; 131(20):5031-40. Fuccillo M, Rallu M, McMahon AP, Fishell G. PMID: 15371303.
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    198. Hedgehog signaling: iguana debuts as a nuclear gatekeeper. Curr Biol. 2004 Aug 24; 14(16):R668-70. Vokes SA, McMahon AP. PMID: 15324687.
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    199. Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell. 2004 Aug 20; 118(4):517-28. Harfe BD, Scherz PJ, Nissim S, Tian H, McMahon AP, Tabin CJ. PMID: 15315763.
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    200. Hedgehog signaling is essential for endothelial tube formation during vasculogenesis. Development. 2004 Sep; 131(17):4371-80. Vokes SA, Yatskievych TA, Heimark RL, McMahon J, McMahon AP, Antin PB, Krieg PA. PMID: 15294868.
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    201. Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse. Development. 2004 Aug; 131(16):4021-33. Tian H, Tenzen T, McMahon AP. PMID: 15269168.
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    202. The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells. Science. 2004 Jul 16; 305(5682):396-9. Scherz PJ, Harfe BD, McMahon AP, Tabin CJ. PMID: 15256670.
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    203. Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Dev Biol. 2004 Jun 15; 270(2):393-410. Lewis PM, Gritli-Linde A, Smeyne R, Kottmann A, McMahon AP. PMID: 15183722.
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    204. Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. J Clin Invest. 2004 Jun; 113(12):1692-700. Rice R, Spencer-Dene B, Connor EC, Gritli-Linde A, McMahon AP, Dickson C, Thesleff I, Rice DP. PMID: 15199404; PMCID: PMC420504.
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    205. Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes Dev. 2004 Apr 15; 18(8):937-51. Jeong J, Mao J, Tenzen T, Kottmann AH, McMahon AP. PMID: 15107405; PMCID: PMC395852.
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    206. Derivation of embryonic stem-cell lines from human blastocysts. N Engl J Med. 2004 Mar 25; 350(13):1353-6. Cowan CA, Klimanskaya I, McMahon J, Atienza J, Witmyer J, Zucker JP, Wang S, Morton CC, McMahon AP, Powers D, Melton DA. PMID: 14999088.
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    207. SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult. Dev Neurosci. 2004 Mar-Aug; 26(2-4):148-65. Ellis P, Fagan BM, Magness ST, Hutton S, Taranova O, Hayashi S, McMahon A, Rao M, Pevny L. PMID: 15711057.
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    208. Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development. 2004 Mar; 131(6):1309-18. Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP. PMID: 14973297.
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    209. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science. 2003 Oct 03; 302(5642):113-7. Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH, Julien JP, Goldstein LS, Cleveland DW. PMID: 14526083.
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    210. Maternal inheritance of Cre activity in a Sox2Cre deleter strain. Genesis. 2003 Oct; 37(2):51-3. Hayashi S, Tenzen T, McMahon AP. PMID: 14595839.
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    211. Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron. 2003 Sep 11; 39(6):937-50. Machold R, Hayashi S, Rutlin M, Muzumdar MD, Nery S, Corbin JG, Gritli-Linde A, Dellovade T, Porter JA, Rubin LL, Dudek H, McMahon AP, Fishell G. PMID: 12971894.
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    212. Combined activities of hedgehog signaling inhibitors regulate pancreas development. Development. 2003 Oct; 130(20):4871-9. Kawahira H, Ma NH, Tzanakakis ES, McMahon AP, Chuang PT, Hebrok M. PMID: 12917290.
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    213. Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance. J Clin Invest. 2003 Aug; 112(4):554-65. Rubera I, Loffing J, Palmer LG, Frindt G, Fowler-Jaeger N, Sauter D, Carroll T, McMahon A, Hummler E, Rossier BC. PMID: 12925696; PMCID: PMC171384.
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    214. Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Development. 2003 Jul; 130(14):3175-85. Majumdar A, Vainio S, Kispert A, McMahon J, McMahon AP. PMID: 12783789.
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    215. Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development. Development. 2003 Jul; 130(13):2967-80. Dakubo GD, Wang YP, Mazerolle C, Campsall K, McMahon AP, Wallace VA. PMID: 12756179.
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    216. Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia. Development. 2003 May; 130(10):2275-87. Ligon KL, Echelard Y, Assimacopoulos S, Danielian PS, Kaing S, Grove EA, McMahon AP, Rowitch DH. PMID: 12668639.
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    217. FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. EMBO J. 2003 Apr 15; 22(8):1811-23. Trokovic R, Trokovic N, Hernesniemi S, Pirvola U, Vogt Weisenhorn DM, Rossant J, McMahon AP, Wurst W, Partanen J. PMID: 12682014; PMCID: PMC154461.
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    218. The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell. 2003 Apr 04; 113(1):11-23. Charron F, Stein E, Jeong J, McMahon AP, Tessier-Lavigne M. PMID: 12679031.
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    219. Branching morphogenesis of the lung: new molecular insights into an old problem. Trends Cell Biol. 2003 Feb; 13(2):86-91. Chuang PT, McMahon AP. PMID: 12559759.
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    220. Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung. Genes Dev. 2003 Feb 01; 17(3):342-7. Chuang PT, Kawcak T, McMahon AP. PMID: 12569124; PMCID: PMC195990.
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    221. Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev. 2003 Feb 01; 17(3):394-409. Barrow JR, Thomas KR, Boussadia-Zahui O, Moore R, Kemler R, Capecchi MR, McMahon AP. PMID: 12569130; PMCID: PMC195987.
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    222. Developmental roles and clinical significance of hedgehog signaling. Curr Top Dev Biol. 2003; 53:1-114. McMahon AP, Ingham PW, Tabin CJ. PMID: 12509125.
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    223. Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Mech Dev. 2002 Dec; 119 Suppl 1:S97-S101. Hayashi S, Lewis P, Pevny L, McMahon AP. PMID: 14516668.
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    224. Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Gene Expr Patterns. 2002 Nov; 2(1-2):93-7. Hayashi S, Lewis P, Pevny L, McMahon AP. PMID: 12617844.
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    225. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol. 2002 Apr 15; 244(2):305-18. Hayashi S, McMahon AP. PMID: 11944939.
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    226. Wnt-1 and Wnt-4 regulate thymic cellularity. Eur J Immunol. 2002 04; 32(4):967-71. Mulroy T, McMahon JA, Burakoff SJ, McMahon AP, Sen J. PMID: 11920562.
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    227. Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes. Mech Dev. 2002 Feb; 111(1-2):75-87. Heanue TA, Davis RJ, Rowitch DH, Kispert A, McMahon AP, Mardon G, Tabin CJ. PMID: 11804780.
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    228. Hedgehog is required for murine yolk sac angiogenesis. Development. 2002 Jan; 129(2):361-72. Byrd N, Becker S, Maye P, Narasimhaiah R, St-Jacques B, Zhang X, McMahon J, McMahon A, Grabel L. PMID: 11807029.
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    229. Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 2001 Dec 01; 15(23):3059-87. Ingham PW, McMahon AP. PMID: 11731473.
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    230. Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development. 2001 Dec; 128(24):5099-108. Long F, Zhang XM, Karp S, Yang Y, McMahon AP. PMID: 11748145.
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    231. BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation. Development. 2001 Nov; 128(22):4523-34. Minina E, Wenzel HM, Kreschel C, Karp S, Gaffield W, McMahon AP, Vortkamp A. PMID: 11714677.
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    232. Wnt7b regulates placental development in mice. Dev Biol. 2001 Sep 15; 237(2):324-32. Parr BA, Cornish VA, Cybulsky MI, McMahon AP. PMID: 11543617.
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    233. Developmental biology. Vesicles and the spinal cord. Nature. 2001 Jul 12; 412(6843):136-7. Jeong J, McMahon AP. PMID: 11449254.
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    234. Six3 promotes the formation of ectopic optic vesicle-like structures in mouse embryos. Dev Dyn. 2001 Jul; 221(3):342-9. Lagutin O, Zhu CC, Furuta Y, Rowitch DH, McMahon AP, Oliver G. PMID: 11458394.
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    235. Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R asymmetry by the mouse node. Cell. 2001 Jun 15; 105(6):781-92. Zhang XM, Ramalho-Santos M, McMahon AP. PMID: 11440720.
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    236. Activation of expression of hedgehog target genes in basal cell carcinomas. J Invest Dermatol. 2001 May; 116(5):739-42. Bonifas JM, Pennypacker S, Chuang PT, McMahon AP, Williams M, Rosenthal A, De Sauvage FJ, Epstein EH. PMID: 11348463.
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    237. Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development. 2001 Apr; 128(8):1253-64. Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, McMahon AP, Sommer L, Boussadia O, Kemler R. PMID: 11262227.
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    238. Hedgehog signaling is required for pituitary gland development. Development. 2001 Feb; 128(3):377-86. Treier M, O'Connell S, Gleiberman A, Price J, Szeto DP, Burgess R, Chuang PT, McMahon AP, Rosenfeld MG. PMID: 11152636.
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    239. Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development. J Clin Invest. 2001 Feb; 107(3):295-304. Chung UI, Schipani E, McMahon AP, Kronenberg HM. PMID: 11160153; PMCID: PMC199199.
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    240. Characterization of Pax-2 regulatory sequences that direct transgene expression in the Wolffian duct and its derivatives. Dev Biol. 2001 Jan 01; 229(1):128-40. Kuschert S, Rowitch DH, Haenig B, McMahon AP, Kispert A. PMID: 11133159.
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    241. Regulation of pancreas development by hedgehog signaling. Development. 2000 Nov; 127(22):4905-13. Hebrok M, Kim SK, St Jacques B, McMahon AP, Melton DA. PMID: 11044404.
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    242. Secreted molecules in metanephric induction. J Am Soc Nephrol. 2000 Nov; 11 Suppl 16:S116-9. Carroll TJ, McMahon AP. PMID: 11065341.
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    243. Sonic hedgehog regulates growth and morphogenesis of the tooth. Development. 2000 Nov; 127(22):4775-85. Dassule HR, Lewis P, Bei M, Maas R, McMahon AP. PMID: 11044393.
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    244. Neural patterning: the role of Nkx genes in the ventral spinal cord. Genes Dev. 2000 Sep 15; 14(18):2261-4. McMahon AP. PMID: 10995382.
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    245. Localization of 17beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase isoform expression in the developing mouse testis--androstenedione is the major androgen secreted by fetal/neonatal leydig cells. Endocrinology. 2000 Jul; 141(7):2631-7. O'Shaughnessy PJ, Baker PJ, Heikkilä M, Vainio S, McMahon AP. PMID: 10875268.
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    246. Hedgehog signals regulate multiple aspects of gastrointestinal development. Development. 2000 Jun; 127(12):2763-72. Ramalho-Santos M, Melton DA, McMahon AP. PMID: 10821773.
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    247. A model for anteroposterior patterning of the vertebrate limb based on sequential long- and short-range Shh signalling and Bmp signalling. Development. 2000 Apr; 127(7):1337-48. Drossopoulou G, Lewis KE, Sanz-Ezquerro JJ, Nikbakht N, McMahon AP, Hofmann C, Tickle C. PMID: 10704381.
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    248. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development. 2000 Apr; 127(8):1671-9. Chai Y, Jiang X, Ito Y, Bringas P, Han J, Rowitch DH, Soriano P, McMahon AP, Sucov HM. PMID: 10725243.
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    249. Fate of the mammalian cardiac neural crest. Development. 2000 Apr; 127(8):1607-16. Jiang X, Rowitch DH, Soriano P, McMahon AP, Sucov HM. PMID: 10725237.
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    250. Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes Dev. 2000 Mar 15; 14(6):650-4. Brisken C, Heineman A, Chavarria T, Elenbaas B, Tan J, Dey SK, McMahon JA, McMahon AP, Weinberg RA. PMID: 10733525; PMCID: PMC316462.
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    251. The organizer factors Chordin and Noggin are required for mouse forebrain development. Nature. 2000 Feb 10; 403(6770):658-61. Bachiller D, Klingensmith J, Kemp C, Belo JA, Anderson RM, May SR, McMahon JA, McMahon AP, Harland RM, Rossant J, De Robertis EM. PMID: 10688202.
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    252. A local Wnt-3a signal is required for development of the mammalian hippocampus. Development. 2000 Feb; 127(3):457-67. Lee SM, Tole S, Grove E, McMahon AP. PMID: 10631167.
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    254. Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways. Development. 2000 Feb; 127(3):543-8. Karp SJ, Schipani E, St-Jacques B, Hunzelman J, Kronenberg H, McMahon AP. PMID: 10631175.
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    255. More surprises in the Hedgehog signaling pathway. Cell. 2000 Jan 21; 100(2):185-8. McMahon AP. PMID: 10660040.
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    257. Pax-2 regulatory sequences that direct transgene expression in the developing neural plate and external granule cell layer of the cerebellum. Brain Res Dev Brain Res. 1999 Oct 20; 117(1):99-108. Rowitch DH, Kispert A, McMahon AP. PMID: 10536237.
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    259. Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds. Nature. 1999 Oct 07; 401(6753):598-602. Zúñiga A, Haramis AP, McMahon AP, Zeller R. PMID: 10524628.
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    260. Schwann Cell-Derived Desert Hedgehog Signals Nerve Sheath Formation. Ann N Y Acad Sci. 1999 Oct; 883(1):196-202. Mirsky R, Parmantier E, McMahon AP, Jessen KR. PMID: 29086927.
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    262. Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev. 1999 Aug 15; 13(16):2072-86. St-Jacques B, Hammerschmidt M, McMahon AP. PMID: 10465785; PMCID: PMC316949.
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    264. Noggin is a mesenchymally derived stimulator of hair-follicle induction. Nat Cell Biol. 1999 Jul; 1(3):158-64. Botchkarev VA, Botchkareva NV, Roth W, Nakamura M, Chen LH, Herzog W, Lindner G, McMahon JA, Peters C, Lauster R, McMahon AP, Paus R. PMID: 10559902.
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    265. Cystic malformation of the posterior cerebellar vermis in transgenic mice that ectopically express Engrailed-1, a homeodomain transcription factor. Teratology. 1999 Jul; 60(1):22-8. Rowitch DH, Danielian PS, McMahon AP, Zec N. PMID: 10413335.
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    266. Modulation of early but not later stages of programmed cell death in embryonic avian spinal cord by sonic hedgehog. Mol Cell Neurosci. 1999 May; 13(5):348-61. Oppenheim RW, Homma S, Marti E, Prevette D, Wang S, Yaginuma H, McMahon AP. PMID: 10356297.
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    267. Negative feedback mechanisms and their roles during pattern formation. Cell. 1999 Apr 02; 97(1):13-6. Perrimon N, McMahon AP. PMID: 10199398.
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    277. Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a. Nature. 1998 Oct 15; 395(6703):707-10. Parr BA, McMahon AP. PMID: 9790192.
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    279. Inhibitory action of BMPs on Pax1 expression and on shoulder girdle formation during limb development. Dev Dyn. 1998 Oct; 213(2):199-206. Hofmann C, Drossopoulou G, McMahon A, Balling R, Tickle C. PMID: 9786420.
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    280. Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Curr Biol. 1998 Sep 24; 8(19):1083-6. Pepicelli CV, Lewis PM, McMahon AP. PMID: 9768363.
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    281. Sonic hedgehog signaling is essential for hair development. Curr Biol. 1998 Sep 24; 8(19):1058-68. St-Jacques B, Dassule HR, Karavanova I, Botchkarev VA, Li J, Danielian PS, McMahon JA, Lewis PM, Paus R, McMahon AP. PMID: 9768360.
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    284. FGF is an essential regulator of the fifth cell division in preimplantation mouse embryos. Dev Biol. 1998 Jun 01; 198(1):105-15. Chai N, Patel Y, Jacobson K, McMahon J, McMahon A, Rappolee DA. PMID: 9640334.
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    355. Cell signalling in induction and anterior-posterior patterning of the vertebrate central nervous system. Curr Opin Neurobiol. 1993 Feb; 3(1):4-7. McMahon AP. PMID: 8453288.
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    356. Cloning developmentally regulated gene families. Methods Enzymol. 1993; 225:653-63. Gavin BJ, McMahon AP. PMID: 8231877.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    357. Factors influencing frequency production of transgenic mice. Methods Enzymol. 1993; 225:771-81. Mann JR, McMahon AP. PMID: 8231885.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    358. Regulation of expression of dopamine beta-hydroxylase in PC12 cells by glucocorticoids and cyclic AMP analogues. J Neurochem. 1992 Dec; 59(6):2040-7. McMahon A, Sabban EL. PMID: 1359011.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    359. The role of Wnt genes in vertebrate development. Curr Opin Genet Dev. 1992 Aug; 2(4):562-6. Dickinson ME, McMahon AP. PMID: 1388080.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    360. Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development. 1992 Jul; 115(3):737-44. Del Amo FF, Smith DE, Swiatek PJ, Gendron-Maguire M, Greenspan RJ, McMahon AP, Gridley T. PMID: 1425352.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    361. Regulation of tyrosine hydroxylase and dopamine beta-hydroxylase mRNA levels in rat adrenals by a single and repeated immobilization stress. J Neurochem. 1992 Jun; 58(6):2124-30. McMahon A, Kvetnanský R, Fukuhara K, Weise VK, Kopin IJ, Sabban EL. PMID: 1349344.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    362. The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell. 1992 May 15; 69(4):581-95. McMahon AP, Joyner AL, Bradley A, McMahon JA. PMID: 1534034.
      View in: PubMed   Mentions: 129     Fields:    Translation:AnimalsCells
    363. Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland. Mol Cell Biol. 1992 May; 12(5):2418-23. Gavin BJ, McMahon AP. PMID: 1373817; PMCID: PMC364414.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    364. Regulated expression of the tyrosine hydroxylase gene by membrane depolarization. Identification of the responsive element and possible second messengers. J Biol Chem. 1992 Apr 15; 267(11):7563-9. Kilbourne EJ, Nankova BB, Lewis EJ, McMahon A, Osaka H, Sabban DB, Sabban EL. PMID: 1348505.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    365. The Wnt family of cell signalling molecules in postimplantation development of the mouse. Ciba Found Symp. 1992; 165:199-212; discussion 212-8. McMahon AP, Gavin BJ, Parr B, Bradley A, McMahon JA. PMID: 1516469.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    366. Membrane depolarization by isotonic or hypertonic KCl: differential effects on mRNA levels of tyrosine hydroxylase and dopamine beta-hydroxylase mRNA in PC12 cells. J Neurosci Methods. 1991 Dec; 40(2-3):193-202. Kilbourne EJ, McMahon A, Sabban EL. PMID: 1686923.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    367. FGFR-4, a new member of the fibroblast growth factor receptor family, expressed in the definitive endoderm and skeletal muscle lineages of the mouse. Development. 1991 Oct; 113(2):641-51. Stark KL, McMahon JA, McMahon AP. PMID: 1723680.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    368. Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis. Development. 1991 Apr; 111(4):1045-55. Christian JL, McMahon JA, McMahon AP, Moon RT. PMID: 1879349.
      View in: PubMed   Mentions: 78     Fields:    Translation:Animals
    369. Isolation of cDNAs partially encoding four Xenopus Wnt-1/int-1-related proteins and characterization of their transient expression during embryonic development. Dev Biol. 1991 Feb; 143(2):230-4. Christian JL, Gavin BJ, McMahon AP, Moon RT. PMID: 1991549.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    370. A new nomenclature for int-1 and related genes: the Wnt gene family. Cell. 1991 Jan 25; 64(2):231. Nusse R, Brown A, Papkoff J, Scambler P, Shackleford G, McMahon A, Moon R, Varmus H. PMID: 1846319.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    371. Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 1990 Dec; 4(12B):2319-32. Gavin BJ, McMahon JA, McMahon AP. PMID: 2279700.
      View in: PubMed   Mentions: 83     Fields:    Translation:AnimalsCells
    372. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell. 1990 Sep 21; 62(6):1073-85. McMahon AP, Bradley A. PMID: 2205396.
      View in: PubMed   Mentions: 418     Fields:    Translation:AnimalsCells
    373. Generation of diversity in nonerythroid spectrins. Multiple polypeptides are predicted by sequence analysis of cDNAs encompassing the coding region of human nonerythroid alpha-spectrin. J Biol Chem. 1990 Mar 15; 265(8):4427-33. Moon RT, McMahon AP. PMID: 2307671.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    374. Rat dopamine beta-hydroxylase: molecular cloning and characterization of the cDNA and regulation of the mRNA by reserpine. J Neurosci Res. 1990 Mar; 25(3):395-404. McMahon A, Geertman R, Sabban EL. PMID: 2325165.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    375. Developmental expression of the putative transcription factor Egr-1 suggests that Egr-1 and c-fos are coregulated in some tissues. Development. 1990 Feb; 108(2):281-7. McMahon AP, Champion JE, McMahon JA, Sukhatme VP. PMID: 2351070.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    376. Effect of compounds which disrupt proton gradients on secretion of neurosecretory proteins from PC12 pheochromocytoma cells. Neuroscience. 1990; 38(2):561-70. Sabban EL, Schwartz J, McMahon A. PMID: 2175857.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    377. Nucleotide sequence, chromosomal localization and developmental expression of the mouse int-1-related gene. Development. 1989 Nov; 107(3):643-50. McMahon JA, McMahon AP. PMID: 2693041.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    378. Endoglycosidase H susceptibility of secreted and intracellular forms of dopamine beta-hydroxylase. Biochem Int. 1989 Oct; 19(4):769-75. Sabban EL, McMahon A, Kuhn LJ. PMID: 2515859.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    379. Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis. Cell. 1989 Sep 22; 58(6):1075-84. McMahon AP, Moon RT. PMID: 2673541.
      View in: PubMed   Mentions: 142     Fields:    Translation:AnimalsCells
    380. int-1--a proto-oncogene involved in cell signalling. Development. 1989; 107 Suppl:161-7. McMahon AP, Moon RT. PMID: 2534596.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    381. Expression pattern of the FGF-related proto-oncogene int-2 suggests multiple roles in fetal development. Development. 1989 Jan; 105(1):131-6. Wilkinson DG, Bhatt S, McMahon AP. PMID: 2680421.
      View in: PubMed   Mentions: 51     Fields:    Translation:Animals
    382. Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse. EMBO J. 1988 Mar; 7(3):691-5. Wilkinson DG, Peters G, Dickson C, McMahon AP. PMID: 3293998; PMCID: PMC454374.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    383. Effects of ionizing radiation and pretreatment with [D-Leu6,des-Gly10] luteinizing hormone-releasing hormone ethylamide on developing rat ovarian follicles. Cancer Res. 1987 Oct 01; 47(19):5005-8. Jarrell J, YoungLai EV, McMahon A, Barr R, O'Connell G, Belbeck L. PMID: 3113726.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    384. Structure and evolution of a non-erythroid spectrin, human alpha-fodrin. Biochem Soc Trans. 1987 Oct; 15(5):804-7. McMahon AP, Moon RT. PMID: 3691949.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    385. Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo. Cell. 1987 Jul 03; 50(1):79-88. Wilkinson DG, Bailes JA, McMahon AP. PMID: 3594565.
      View in: PubMed   Mentions: 117     Fields:    Translation:AnimalsCells
    386. Ovarian toxicity of cyclophosphamide alone and in combination with ovarian irradiation in the rat. Cancer Res. 1987 May 01; 47(9):2340-3. Jarrell J, Lai EV, Barr R, McMahon A, Belbeck L, O'Connell G. PMID: 3105875.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    387. A molecular analysis of mouse development from 8 to 10 days post coitum detects changes only in embryonic globin expression. Development. 1987 Apr; 99(4):493-500. Wilkinson DG, Bailes JA, Champion JE, McMahon AP. PMID: 2444404.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    388. cDNA cloning, sequencing and chromosome mapping of a non-erythroid spectrin, human alpha-fodrin. Differentiation. 1987; 34(1):68-78. McMahon AP, Giebelhaus DH, Champion JE, Bailes JA, Lacey S, Carritt B, Henchman SK, Moon RT. PMID: 3038643.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    389. An analysis of the effects of increasing doses of ionizing radiation to the exteriorized rat ovary on follicular development, atresia, and serum gonadotropin levels. Am J Obstet Gynecol. 1986 Feb; 154(2):306-9. Jarrell J, YoungLai EV, Barr R, O'Connell G, Belbeck L, McMahon A. PMID: 3080889.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    390. Introduction of cloned DNA into sea urchin egg cytoplasm: replication and persistence during embryogenesis. Dev Biol. 1985 Apr; 108(2):420-30. McMahon AP, Flytzanis CN, Hough-Evans BR, Katula KS, Britten RJ, Davidson EH. PMID: 3000854.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    391. Persistence and integration of cloned DNA in postembryonic sea urchins. Dev Biol. 1985 Apr; 108(2):431-42. Flytzanis CN, McMahon AP, Hough-Evans BR, Katula KS, Britten RJ, Davidson EH. PMID: 3000855.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    392. Inducible expression of a cloned heat shock fusion gene in sea urchin embryos. Proc Natl Acad Sci U S A. 1984 Dec; 81(23):7490-4. McMahon AP, Novak TJ, Britten RJ, Davidson EH. PMID: 6594699; PMCID: PMC392172.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    393. Oocyte specific regulation of PGK-1 isozyme activity in female germ cells of the mouse. Genet Res. 1983 Aug; 42(1):77-89. McMahon A. PMID: 6628991.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    394. X-chromosome inactivation mosaicism in the three germ layers and the germ line of the mouse embryo. J Embryol Exp Morphol. 1983 Apr; 74:207-20. McMahon A, Fosten M, Monk M. PMID: 6886595.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    395. X-chromosome activity in female mouse embryos heterozygous for Pgk-1 and Searle's translocation, T(X; 16) 16H. Genet Res. 1983 Feb; 41(1):69-83. McMahon A, Monk M. PMID: 6840549.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    396. Random X-chromosome inactivation in female primordial germ cells in the mouse. J Embryol Exp Morphol. 1981 Aug; 64:251-8. McMahon A, Fosten M, Monk M. PMID: 7310304.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
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