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Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development. Dev Cell. 2024 Aug 07.
Kim S, Koppitch K, Parvez RK, Guo J, Achieng M, Schnell J, Lindström NO, McMahon AP. PMID: 39121855.
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PubMed Mentions:
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Molecular motor tug-of-war regulates elongasome cell wall synthesis dynamics in Bacillus subtilis. Nat Commun. 2024 Jun 26; 15(1):5411.
Middlemiss S, Blandenet M, Roberts DM, McMahon A, Grimshaw J, Edwards JM, Sun Z, Whitley KD, Blu T, Strahl H, Holden S. PMID: 38926336; PMCID: PMC11208587.
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PubMed Mentions: Fields:
Translation:
Cells
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Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease. Cell Stem Cell. 2024 Jun 06; 31(6):921-939.e17.
Huang B, Zeng Z, Kim S, Fausto CC, Koppitch K, Li H, Li Z, Chen X, Guo J, Zhang CC, Ma T, Medina P, Schreiber ME, Xia MW, Vonk AC, Xiang T, Patel T, Li Y, Parvez RK, Der B, Chen JH, Liu Z, Thornton ME, Grubbs BH, Diao Y, Dou Y, Gnedeva K, Ying Q, Pastor-Soler NM, Fei T, Hallows KR, Lindström NO, McMahon AP, Li Z. PMID: 38692273; PMCID: PMC11162329.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Spatial transcriptomics defines injury-specific microenvironments in the adult mouse kidney and novel cellular interactions in regeneration and disease. bioRxiv. 2023 Nov 22.
Polonsky M, Gerhardt LMS, Yun J, Koppitch K, Colón KL, Amrhein H, Zheng S, Yuan GC, Thomson M, Cai L, McMahon AP. PMID: 38045285; PMCID: PMC10690238.
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PubMed Mentions:
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Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney. Dev Cell. 2023 11 06; 58(21):2338-2358.e5.
Xiong L, Liu J, Han SY, Koppitch K, Guo JJ, Rommelfanger M, Miao Z, Gao F, Hallgrimsdottir IB, Pachter L, Kim J, MacLean AL, McMahon AP. PMID: 37673062; PMCID: PMC10873092.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Cadherin Adhesion Complexes Direct Cell Aggregation in the Epithelial Transition of Wnt-Induced Nephron Progenitor Cells. bioRxiv. 2023 Aug 27.
Der B, Bugacov H, Briantseva BM, McMahon AP. PMID: 38654822; PMCID: PMC11037868.
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PubMed Mentions:
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Canonical Wnt transcriptional complexes are essential for induction of nephrogenesis but not maintenance or proliferation of nephron progenitors. bioRxiv. 2023 Aug 21.
Bugacov H, Der B, Kim S, Lindström NO, McMahon AP. PMID: 37662369; PMCID: PMC10473675.
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PubMed Mentions:
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User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium. APL Bioeng. 2023 Sep; 7(3):036106.
Khalil NN, Petersen AP, Song CJ, Chen Y, Takamoto K, Kellogg AC, Chen EZ, McMahon AP, McCain ML. PMID: 37584027; PMCID: PMC10424157.
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PubMed Mentions:
1
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Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids. bioRxiv. 2023 May 25.
Huang B, Zeng Z, Li H, Li Z, Chen X, Guo J, Zhang CC, Schreiber ME, Vonk AC, Xiang T, Patel T, Li Y, Parvez RK, Der B, Chen JH, Liu Z, Thornton ME, Grubbs BH, Diao Y, Dou Y, Gnedeva K, Lindström NO, Ying Q, Pastor-Soler NM, Fei T, Hallows KR, McMahon AP, Li Z. PMID: 37293038; PMCID: PMC10245960.
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PubMed Mentions:
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Direct androgen receptor regulation of sexually dimorphic gene expression in the mammalian kidney. bioRxiv. 2023 May 25.
Xiong L, Liu J, Han SY, Koppitch K, Guo JJ, Rommelfanger M, Gao F, Hallgrimsdottir IB, Pachter L, Kim J, MacLean AL, McMahon AP. PMID: 37205355; PMCID: PMC10187285.
View in:
PubMed Mentions:
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Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development. bioRxiv. 2023 May 17.
Kim S, Koppitch K, Parvez RK, Guo J, Achieng M, Schnell J, Lindström NO, McMahon AP. PMID: 37293066; PMCID: PMC10245679.
View in:
PubMed Mentions:
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Proximal tubule responses to injury: interrogation by single-cell transcriptomics. Curr Opin Nephrol Hypertens. 2023 07 01; 32(4):352-358.
Cippà PE, McMahon AP. PMID: 37074682; PMCID: PMC10330172.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Lineage Tracing and Single-Nucleus Multiomics Reveal Novel Features of Adaptive and Maladaptive Repair after Acute Kidney Injury. J Am Soc Nephrol. 2023 04 01; 34(4):554-571.
Gerhardt LMS, Koppitch K, van Gestel J, Guo J, Cho S, Wu H, Kirita Y, Humphreys BD, McMahon AP. PMID: 36735940; PMCID: PMC10103206.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Identifying Common Molecular Mechanisms in Experimental and Human Acute Kidney Injury. Semin Nephrol. 2022 05; 42(3):151286.
Gerhardt LMS, McMahon AP. PMID: 36402654; PMCID: PMC11017289.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages. Cell Rep. 2022 09 06; 40(10):111315.
Hojo H, Saito T, He X, Guo Q, Onodera S, Azuma T, Koebis M, Nakao K, Aiba A, Seki M, Suzuki Y, Okada H, Tanaka S, Chung UI, McMahon AP, Ohba S. PMID: 36070691; PMCID: PMC9510047.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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A genetic model for in vivo proximity labelling of the mammalian secretome. Open Biol. 2022 08; 12(8):220149.
Yang R, Meyer AS, Droujinine IA, Udeshi ND, Hu Y, Guo J, McMahon JA, Carey DK, Xu C, Fang Q, Sha J, Qin S, Rocco D, Wohlschlegel J, Ting AY, Carr SA, Perrimon N, McMahon AP. PMID: 35946312; PMCID: PMC9364151.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery. Cell Stem Cell. 2022 07 07; 29(7):1083-1101.e7.
Tran T, Song CJ, Nguyen T, Cheng SY, McMahon JA, Yang R, Guo Q, Der B, Lindström NO, Lin DC, McMahon AP. PMID: 35803227; PMCID: PMC11088748.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
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Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing. Proc Natl Acad Sci U S A. 2022 06 21; 119(25):e2203179119.
Xu J, Liu Y, Li H, Tarashansky AJ, Kalicki CH, Hung RJ, Hu Y, Comjean A, Kolluru SS, Wang B, Quake SR, Luo L, McMahon AP, Dow JAT, Perrimon N. PMID: 35696569; PMCID: PMC9231607.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Kidney repair and regeneration: perspectives of the NIDDK (Re)Building a Kidney consortium. Kidney Int. 2022 05; 101(5):845-853.
Naved BA, Bonventre JV, Hubbell JA, Hukriede NA, Humphreys BD, Kesselman C, Valerius MT, McMahon AP, Shankland SJ, Wertheim JA, White MJV, de Caestecker MP, Drummond IA. PMID: 35276204; PMCID: PMC9045003.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
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Repairing the blood-brain barrier. Science. 2022 02 18; 375(6582):715-716.
McMahon AP, Ichida JK. PMID: 35175806.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Multi-omic approaches to acute kidney injury and repair. Curr Opin Biomed Eng. 2021 Dec; 20.
Gerhardt LMS, McMahon AP. PMID: 35005326; PMCID: PMC8740908.
View in:
PubMed Mentions:
6
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Spatial transcriptional mapping of the human nephrogenic program. Dev Cell. 2021 08 23; 56(16):2381-2398.e6.
Lindström NO, Sealfon R, Chen X, Parvez RK, Ransick A, De Sena Brandine G, Guo J, Hill B, Tran T, Kim AD, Zhou J, Tadych A, Watters A, Wong A, Lovero E, Grubbs BH, Thornton ME, McMahon JA, Smith AD, Ruffins SW, Armit C, Troyanskaya OG, McMahon AP. PMID: 34428401; PMCID: PMC8396064.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Multi-omics integration in the age of million single-cell data. Nat Rev Nephrol. 2021 11; 17(11):710-724.
Miao Z, Humphreys BD, McMahon AP, Kim J. PMID: 34417589; PMCID: PMC9191639.
View in:
PubMed Mentions:
56 Fields:
Translation:
Humans
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Single-nuclear transcriptomics reveals diversity of proximal tubule cell states in a dynamic response to acute kidney injury. Proc Natl Acad Sci U S A. 2021 07 06; 118(27).
Gerhardt LMS, Liu J, Koppitch K, Cippà PE, McMahon AP. PMID: 34183416; PMCID: PMC8271768.
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PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
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Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors. Nat Commun. 2021 06 15; 12(1):3641.
Zeng Z, Huang B, Parvez RK, Li Y, Chen J, Vonk AC, Thornton ME, Patel T, Rutledge EA, Kim AD, Yu J, Grubbs BH, McMahon JA, Pastor-Soler NM, Hallows KR, McMahon AP, Li Z. PMID: 34131121; PMCID: PMC8206157.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Correction: A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells. Elife. 2021 Apr 29; 10.
Guo Q, Kim AD, Li B, Ransick A, Bugacov H, Chen X, Lindström NO, Brown A, Oxburgh L, Ren B, McMahon AP. PMID: 33913807; PMCID: PMC8084526.
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PubMed Mentions: Fields:
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Proteomics of protein trafficking by in vivo tissue-specific labeling. Nat Commun. 2021 04 22; 12(1):2382.
Droujinine IA, Meyer AS, Wang D, Udeshi ND, Hu Y, Rocco D, McMahon JA, Yang R, Guo J, Mu L, Carey DK, Svinkina T, Zeng R, Branon T, Tabatabai A, Bosch JA, Asara JM, Ting AY, Carr SA, McMahon AP, Perrimon N. PMID: 33888706; PMCID: PMC8062696.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells. Elife. 2021 02 15; 10.
Guo Q, Kim A, Li B, Ransick A, Bugacov H, Chen X, Lindström N, Brown A, Oxburgh L, Ren B, McMahon AP. PMID: 33587034; PMCID: PMC7924951.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Author Correction: Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality. Nat Metab. 2020 09; 2(9):989.
Legouis D, Ricksten SE, Faivre A, Verissimo T, Gariani K, Verney C, Galichon P, Berchtold L, Feraille E, Fernandez M, Placier S, Koppitch K, Hertig A, Martin PY, Naesens M, Pugin J, McMahon AP, Cippà PE, de Seigneux S. PMID: 32873966.
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PubMed Mentions:
1 Fields:
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Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality. Nat Metab. 2020 08; 2(8):732-743.
Legouis D, Ricksten SE, Faivre A, Verissimo T, Gariani K, Verney C, Galichon P, Berchtold L, Feraille E, Fernandez M, Placier S, Koppitch K, Hertig A, Martin PY, Naesens M, Pugin J, McMahon AP, Cippà PE, de Seigneux S. PMID: 32694833.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
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A novel distal convoluted tubule-specific Cre-recombinase driven by the NaCl cotransporter gene. Am J Physiol Renal Physiol. 2020 09 01; 319(3):F423-F435.
Cornelius RJ, Sharma A, Su XT, Guo JJ, McMahon JA, Ellison DH, McMahon AP, McCormick JA. PMID: 32657158; PMCID: PMC7509282.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Mutational analysis of genes with ureteric progenitor cell-specific expression in branching morphogenesis of the mouse kidney. Dev Dyn. 2020 06; 249(6):765-774.
Rutledge EA, McMahon AP. PMID: 32017326; PMCID: PMC7679181.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury. J Am Soc Nephrol. 2020 04; 31(4):701-715.
Liu J, Kumar S, Heinzel A, Gao M, Guo J, Alvarado GF, Reindl-Schwaighofer R, Krautzberger AM, Cippà PE, McMahon J, Oberbauer R, McMahon AP. PMID: 32034106; PMCID: PMC7191932.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimals
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Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system. Dev Biol. 2020 02 15; 458(2):164-176.
Rutledge EA, Lindström NO, Michos O, McMahon AP. PMID: 31734175; PMCID: PMC6995766.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney. Dev Cell. 2019 11 04; 51(3):399-413.e7.
Ransick A, Lindström NO, Liu J, Zhu Q, Guo JJ, Alvarado GF, Kim AD, Black HG, Kim J, McMahon AP. PMID: 31689386; PMCID: PMC6948019.
View in:
PubMed Mentions:
154 Fields:
Translation:
AnimalsCells
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Cellular Recruitment by Podocyte-Derived Pro-migratory Factors in Assembly of the Human Renal Filter. iScience. 2019 Oct 25; 20:402-414.
Kim AD, Lake BB, Chen S, Wu Y, Guo J, Parvez RK, Tran T, Thornton ME, Grubbs B, McMahon JA, Zhang K, McMahon AP. PMID: 31622881; PMCID: PMC6817668.
View in:
PubMed Mentions:
6
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In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes. Dev Cell. 2019 07 01; 50(1):102-116.e6.
Tran T, Lindström NO, Ransick A, De Sena Brandine G, Guo Q, Kim AD, Der B, Peti-Peterdi J, Smith AD, Thornton M, Grubbs B, McMahon JA, McMahon AP. PMID: 31265809; PMCID: PMC6684316.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Dev Biol. 2019 10 15; 454(2):156-169.
Rutledge EA, Parvez RK, Short KM, Smyth IM, McMahon AP. PMID: 31242448; PMCID: PMC6726516.
View in:
PubMed Mentions:
13 Fields:
Translation:
Animals
-
A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation. Nat Commun. 2019 03 11; 10(1):1157.
Cippà PE, Liu J, Sun B, Kumar S, Naesens M, McMahon AP. PMID: 30858375; PMCID: PMC6411919.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback. Nat Commun. 2019 01 16; 10(1):239.
Menshykau D, Michos O, Lang C, Conrad L, McMahon AP, Iber D. PMID: 30651543; PMCID: PMC6484223.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment. Elife. 2018 12 05; 7.
O'Brien LL, Combes AN, Short KM, Lindström NO, Whitney PH, Cullen-McEwen LA, Ju A, Abdelhalim A, Michos O, Bertram JF, Smyth IM, Little MH, McMahon AP. PMID: 30516471; PMCID: PMC6281319.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Transcriptional trajectories of human kidney injury progression. JCI Insight. 2018 11 15; 3(22).
Cippà PE, Sun B, Liu J, Chen L, Naesens M, McMahon AP. PMID: 30429361; PMCID: PMC6302941.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
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Single-Cell RNA Sequencing of the Adult Mouse Kidney: From Molecular Cataloging of Cell Types to Disease-Associated Predictions. Am J Kidney Dis. 2019 01; 73(1):140-142.
Lindström NO, De Sena Brandine G, Ransick A, McMahon AP. PMID: 30241960; PMCID: PMC6480390.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through Cdk6 expression. Development. 2018 08 20; 145(17).
Hasenpusch-Theil K, West S, Kelman A, Kozic Z, Horrocks S, McMahon AP, Price DJ, Mason JO, Theil T. PMID: 30093555; PMCID: PMC6141774.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells. Stem Cell Reports. 2018 08 14; 11(2):470-484.
Przepiorski A, Sander V, Tran T, Hollywood JA, Sorrenson B, Shih JH, Wolvetang EJ, McMahon AP, Holm TM, Davidson AJ. PMID: 30033089; PMCID: PMC6092837.
View in:
PubMed Mentions:
101 Fields:
Translation:
HumansCells
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Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis. Dev Cell. 2018 06 04; 45(5):651-660.e4.
Lindström NO, De Sena Brandine G, Tran T, Ransick A, Suh G, Guo J, Kim AD, Parvez RK, Ruffins SW, Rutledge EA, Thornton ME, Grubbs B, McMahon JA, Smith AD, McMahon AP. PMID: 29870722; PMCID: PMC6510587.
View in:
PubMed Mentions:
89 Fields:
Translation:
HumansAnimalsCells
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Disparate levels of beta-catenin activity determine nephron progenitor cell fate. Dev Biol. 2018 08 01; 440(1):13-21.
Ramalingam H, Fessler AR, Das A, Valerius MT, Basta J, Robbins L, Brown AC, Oxburgh L, McMahon AP, Rauchman M, Carroll TJ. PMID: 29705331; PMCID: PMC5988999.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions. PLoS Genet. 2018 04; 14(4):e1007346.
Tan Z, Niu B, Tsang KY, Melhado IG, Ohba S, He X, Huang Y, Wang C, McMahon AP, Jauch R, Chan D, Zhang MQ, Cheah KSE. PMID: 29659575; PMCID: PMC5919691.
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PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
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Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney. J Am Soc Nephrol. 2018 03; 29(3):806-824.
Lindström NO, Guo J, Kim AD, Tran T, Guo Q, De Sena Brandine G, Ransick A, Parvez RK, Thornton ME, Baskin L, Grubbs B, McMahon JA, Smith AD, McMahon AP. PMID: 29449449; PMCID: PMC5827607.
View in:
PubMed Mentions:
97 Fields:
Translation:
HumansAnimalsCells
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Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning. J Am Soc Nephrol. 2018 03; 29(3):825-840.
Lindström NO, Tran T, Guo J, Rutledge E, Parvez RK, Thornton ME, Grubbs B, McMahon JA, McMahon AP. PMID: 29449451; PMCID: PMC5827611.
View in:
PubMed Mentions:
63 Fields:
Translation:
HumansAnimalsCells
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Conserved and Divergent Features of Human and Mouse Kidney Organogenesis. J Am Soc Nephrol. 2018 03; 29(3):785-805.
Lindström NO, McMahon JA, Guo J, Tran T, Guo Q, Rutledge E, Parvez RK, Saribekyan G, Schuler RE, Liao C, Kim AD, Abdelhalim A, Ruffins SW, Thornton ME, Baskin L, Grubbs B, Kesselman C, McMahon AP. PMID: 29449453; PMCID: PMC5827606.
View in:
PubMed Mentions:
95 Fields:
Translation:
HumansAnimals
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Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies. PLoS Genet. 2018 01; 14(1):e1007181.
O'Brien LL, Guo Q, Bahrami-Samani E, Park JS, Hasso SM, Lee YJ, Fang A, Kim AD, Guo J, Hong TM, Peterson KA, Lozanoff S, Raviram R, Ren B, Fogelgren B, Smith AD, Valouev A, McMahon AP. PMID: 29377931; PMCID: PMC5805373.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Development of the Human Fetal Kidney from Mid to Late Gestation in Male and Female Infants. EBioMedicine. 2018 Jan; 27:275-283.
Ryan D, Sutherland MR, Flores TJ, Kent AL, Dahlstrom JE, Puelles VG, Bertram JF, McMahon AP, Little MH, Moore L, Black MJ. PMID: 29329932; PMCID: PMC5828465.
View in:
PubMed Mentions:
54 Fields:
Translation:
Humans
-
An immunohistochemical identification key for cell types in adult mouse prostatic and urethral tissue sections. PLoS One. 2017; 12(11):e0188413.
Wegner KA, Cadena MT, Trevena R, Turco AE, Gottschalk A, Halberg RB, Guo J, McMahon JA, McMahon AP, Vezina CM. PMID: 29145476; PMCID: PMC5690684.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Determination of Total Biotin by Liquid Chromatography Coupled with Immunoaffinity Column Cleanup Extraction: Multilaboratory Testing, Final Action 2016.02. J AOAC Int. 2018 May 01; 101(3):831-842.
Joseph G, Devi R, Marley EC, Leeman D, Bhandari S, Butler Thompson L, Campos Giminez E, Chen H, Dekker N, Devi R, Dole M, Gallegos-Peretz T, Gill B, Gill T, Green Y, Hodgson M, Huo X, Indyk H, Joseph G, Kennedy L, Leeman D, Lim F, Macfadzean C, McMahon A, Malaviole I, Marley E, Seegers M, Schimpf K, Wang J, Wollard D, Yadlapalli S, Yin C. PMID: 29021006.
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PubMed Mentions: Fields:
Translation:
Humans
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Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion. JCI Insight. 2017 09 21; 2(18).
Liu J, Kumar S, Dolzhenko E, Alvarado GF, Guo J, Lu C, Chen Y, Li M, Dessing MC, Parvez RK, Cippà PE, Krautzberger AM, Saribekyan G, Smith AD, McMahon AP. PMID: 28931758; PMCID: PMC5612583.
View in:
PubMed Mentions:
122 Fields:
Translation:
Animals
-
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 09 01; 144(17):3177-3188.
Rutledge EA, Benazet JD, McMahon AP. PMID: 28705898; PMCID: PMC5611955.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimals
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Sox9 positive periosteal cells in fracture repair of the adult mammalian long bone. Bone. 2017 Oct; 103:12-19.
He X, Bougioukli S, Ortega B, Arevalo E, Lieberman JR, McMahon AP. PMID: 28627474; PMCID: PMC6435293.
View in:
PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 05 22; 41(4):349-365.e3.
Naiman N, Fujioka K, Fujino M, Valerius MT, Potter SS, McMahon AP, Kobayashi A. PMID: 28535371; PMCID: PMC5532731.
View in:
PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
-
A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking. Dev Cell. 2017 03 13; 40(5):439-452.e4.
Minegishi K, Hashimoto M, Ajima R, Takaoka K, Shinohara K, Ikawa Y, Nishimura H, McMahon AP, Willert K, Okada Y, Sasaki H, Shi D, Fujimori T, Ohtsuka T, Igarashi Y, Yamaguchi TP, Shimono A, Shiratori H, Hamada H. PMID: 28292423; PMCID: PMC7974384.
View in:
PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
-
Hedgehog Signaling: From Basic Biology to Cancer Therapy. Cell Chem Biol. 2017 Mar 16; 24(3):252-280.
Wu F, Zhang Y, Sun B, McMahon AP, Wang Y. PMID: 28286127; PMCID: PMC7442121.
View in:
PubMed Mentions:
148 Fields:
Translation:
HumansCells
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(Re)Building a Kidney. J Am Soc Nephrol. 2017 May; 28(5):1370-1378.
Oxburgh L, Carroll TJ, Cleaver O, Gossett DR, Hoshizaki DK, Hubbell JA, Humphreys BD, Jain S, Jensen J, Kaplan DL, Kesselman C, Ketchum CJ, Little MH, McMahon AP, Shankland SJ, Spence JR, Valerius MT, Wertheim JA, Wessely O, Zheng Y, Drummond IA. PMID: 28096308; PMCID: PMC5407737.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Correction: Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation. PLoS Genet. 2016 Dec; 12(12):e1006533.
Hoffmann AD, Yang XH, Burnicka-Turek O, Bosman JD, Ren X, Xie L, Steimle JD, Vokes SA, McMahon AP, Kalinichenko VV, Moskowitz IP. PMID: 28033319; PMCID: PMC5199006.
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PubMed Mentions: Fields:
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An Emerging Regulatory Landscape for Skeletal Development. Trends Genet. 2016 12; 32(12):774-787.
Hojo H, McMahon AP, Ohba S. PMID: 27814929; PMCID: PMC5126973.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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AP-1 family members act with Sox9 to promote chondrocyte hypertrophy. Development. 2016 08 15; 143(16):3012-23.
He X, Ohba S, Hojo H, McMahon AP. PMID: 27471255; PMCID: PMC5004882.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Sonoelastography of the Achilles Tendon: Prevalence and Prognostic Value Among Asymptomatic Elite Australian Rules Football Players. Clin J Sport Med. 2016 Jul; 26(4):299-306.
Ooi CC, Schneider ME, Malliaras P, Jones D, Saunders S, McMahon A, Connell D. PMID: 26513392.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1. Elife. 2016 05 05; 5.
Lorberbaum DS, Ramos AI, Peterson KA, Carpenter BS, Parker DS, De S, Hillers LE, Blake VM, Nishi Y, McFarlane MR, Chiang AC, Kassis JA, Allen BL, McMahon AP, Barolo S. PMID: 27146892; PMCID: PMC4887206.
View in:
PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Sp7/Osterix Is Restricted to Bone-Forming Vertebrates where It Acts as a Dlx Co-factor in Osteoblast Specification. Dev Cell. 2016 05 09; 37(3):238-53.
Hojo H, Ohba S, He X, Lai LP, McMahon AP. PMID: 27134141; PMCID: PMC4964983.
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PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
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Stem cells for all ages, yet hostage to aging. Stem Cell Investig. 2016; 3:11.
Finch CE, McMahon AP. PMID: 27357142; PMCID: PMC4923636.
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PubMed Mentions:
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Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators. Development. 2016 Feb 15; 143(4):595-608.
O'Brien LL, Guo Q, Lee Y, Tran T, Benazet JD, Whitney PH, Valouev A, McMahon AP. PMID: 26884396; PMCID: PMC4760318.
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PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Development of the Mammalian Kidney. Curr Top Dev Biol. 2016; 117:31-64.
McMahon AP. PMID: 26969971; PMCID: PMC5007134.
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PubMed Mentions:
125 Fields:
Translation:
HumansAnimals
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Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State. Dev Cell. 2015 Nov 09; 35(3):358-65.
Askary A, Mork L, Paul S, He X, Izuhara AK, Gopalakrishnan S, Ichida JK, McMahon AP, Dabizljevic S, Dale R, Mariani FV, Crump JG. PMID: 26555055; PMCID: PMC4758819.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity. Exp Cell Res. 2016 Jan 01; 340(1):43-52.
Hettmer S, Lin MM, Tchessalova D, Tortorici SJ, Castiglioni A, Desai T, Mao J, McMahon AP, Wagers AJ. PMID: 26460176; PMCID: PMC4718790.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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A direct fate exclusion mechanism by Sonic hedgehog-regulated transcriptional repressors. Development. 2015 Oct 01; 142(19):3286-93.
Nishi Y, Zhang X, Jeong J, Peterson KA, Vedenko A, Bulyk ML, Hide WA, McMahon AP. PMID: 26293298; PMCID: PMC4631756.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney. Cell Rep. 2015 Aug 25; 12(8):1325-38.
Kumar S, Liu J, Pang P, Krautzberger AM, Reginensi A, Akiyama H, Schedl A, Humphreys BD, McMahon AP. PMID: 26279573.
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PubMed Mentions:
94 Fields:
Translation:
AnimalsCells
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Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte. Cell Rep. 2015 Jul 14; 12(2):229-43.
Ohba S, He X, Hojo H, McMahon AP. PMID: 26146088; PMCID: PMC4504750.
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PubMed Mentions:
94 Fields:
Translation:
HumansAnimalsCells
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A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning. Dev Cell. 2014 Nov 24; 31(4):448-60.
Junker JP, Peterson KA, Nishi Y, Mao J, McMahon AP, van Oudenaarden A. PMID: 25458012.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation. PLoS Genet. 2014 Oct; 10(10):e1004604.
Hoffmann AD, Yang XH, Burnicka-Turek O, Bosman JD, Ren X, Steimle JD, Vokes SA, McMahon AP, Kalinichenko VV, Moskowitz IP. PMID: 25356765; PMCID: PMC4214600.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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Genome-wide RNA Tomography in the zebrafish embryo. Cell. 2014 Oct 23; 159(3):662-75.
Junker JP, Noël ES, Guryev V, Peterson KA, Shah G, Huisken J, McMahon AP, Berezikov E, Bakkers J, van Oudenaarden A. PMID: 25417113.
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PubMed Mentions:
124 Fields:
Translation:
Animals
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Stk11 (Lkb1) deletion in the osteoblast lineage leads to high bone turnover, increased trabecular bone density and cortical porosity. Bone. 2014 Dec; 69:98-108.
Lai LP, Lotinun S, Bouxsein ML, Baron R, McMahon AP. PMID: 25240456; PMCID: PMC4373701.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Identification of a multipotent self-renewing stromal progenitor population during mammalian kidney organogenesis. Stem Cell Reports. 2014 Oct 14; 3(4):650-62.
Kobayashi A, Mugford JW, Krautzberger AM, Naiman N, Liao J, McMahon AP. PMID: 25358792; PMCID: PMC4223698.
View in:
PubMed Mentions:
110 Fields:
Translation:
AnimalsCells
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Induction and patterning of the metanephric nephron. Semin Cell Dev Biol. 2014 Dec; 36:31-8.
O'Brien LL, McMahon AP. PMID: 25194660; PMCID: PMC4252735.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs. Nature. 2014 Jul 03; 511(7507):46-51.
Lopez-Rios J, Duchesne A, Speziale D, Andrey G, Peterson KA, Germann P, Unal E, Liu J, Floriot S, Barbey S, Gallard Y, Müller-Gerbl M, Courtney AD, Klopp C, Rodriguez S, Ivanek R, Beisel C, Wicking C, Iber D, Robert B, McMahon AP, Duboule D, Zeller R. PMID: 24990743.
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PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
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Defining the acute kidney injury and repair transcriptome. Semin Nephrol. 2014 Jul; 34(4):404-17.
Kumar S, Liu J, McMahon AP. PMID: 25217269; PMCID: PMC4163949.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Collecting duct-derived cells display mesenchymal stem cell properties and retain selective in vitro and in vivo epithelial capacity. J Am Soc Nephrol. 2015 Jan; 26(1):81-94.
Li J, Ariunbold U, Suhaimi N, Sunn N, Guo J, McMahon JA, McMahon AP, Little M. PMID: 24904087; PMCID: PMC4279727.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Global quantification of tissue dynamics in the developing mouse kidney. Dev Cell. 2014 Apr 28; 29(2):188-202.
Short KM, Combes AN, Lefevre J, Ju AL, Georgas KM, Lamberton T, Cairncross O, Rumballe BA, McMahon AP, Hamilton NA, Smyth IM, Little MH. PMID: 24780737.
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PubMed Mentions:
123 Fields:
Translation:
AnimalsCells
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Translational profiles of medullary myofibroblasts during kidney fibrosis. J Am Soc Nephrol. 2014 Sep; 25(9):1979-90.
Grgic I, Krautzberger AM, Hofmeister A, Lalli M, DiRocco DP, Fleig SV, Liu J, Duffield JS, McMahon AP, Aronow B, Humphreys BD. PMID: 24652793; PMCID: PMC4147988.
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PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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Cell-specific translational profiling in acute kidney injury. J Clin Invest. 2014 Mar; 124(3):1242-54.
Liu J, Krautzberger AM, Sui SH, Hofmann OM, Chen Y, Baetscher M, Grgic I, Kumar S, Humphreys BD, Humphreys B, Hide WA, McMahon AP. PMID: 24569379; PMCID: PMC3938273.
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PubMed Mentions:
103 Fields:
Translation:
AnimalsCells
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Defining kidney biology to understand renal disease. Clin J Am Soc Nephrol. 2014 Apr; 9(4):809-11.
Little MH, Brown D, Humphreys BD, McMahon AP, Miner JH, Sands JM, Weisz OA, Mullins C, Hoshizaki D, Kidney Research National Dialogue (KRND). PMID: 24370769; PMCID: PMC3974369.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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A novel site comes into sight. Elife. 2013 Dec 03; 2:e01680.
Wang Y, McMahon AP. PMID: 24302574; PMCID: PMC3847883.
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PubMed Mentions: Fields:
Translation:
Animals
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Gene regulatory networks mediating canonical Wnt signal-directed control of pluripotency and differentiation in embryo stem cells. Stem Cells. 2013 Dec; 31(12):2667-79.
Zhang X, Peterson KA, Liu XS, McMahon AP, Ohba S. PMID: 23505158; PMCID: PMC3830733.
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PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
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Distinct cellular origin and genetic requirement of Hedgehog-Gli in postnatal rhabdomyosarcoma genesis. Oncogene. 2014 Nov 13; 33(46):5370-8.
Rajurkar M, Huang H, Cotton JL, Brooks JK, Sicklick J, McMahon AP, Mao J. PMID: 24276242; PMCID: PMC4309268.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19450-5.
Lai LP, Lilley BN, Sanes JR, McMahon AP. PMID: 24218567; PMCID: PMC3845115.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Mutations in Hedgehog pathway genes in fetal rhabdomyomas. J Pathol. 2013 Sep; 231(1):44-52.
Hettmer S, Teot LA, van Hummelen P, MacConaill L, Bronson RT, Dall'Osso C, Mao J, McMahon AP, Gruber PJ, Grier HE, Rodriguez-Galindo C, Fletcher CD, Wagers AJ. PMID: 23780909; PMCID: PMC3875333.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
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Retinoid signaling in progenitors controls specification and regeneration of the urothelium. Dev Cell. 2013 Sep 16; 26(5):469-482.
Gandhi D, Molotkov A, Batourina E, Schneider K, Dan H, Reiley M, Laufer E, Metzger D, Liang F, Liao Y, Sun TT, Aronow B, Rosen R, Mauney J, Adam R, Rosselot C, Van Batavia J, McMahon A, McMahon J, Guo JJ, Mendelsohn C. PMID: 23993789; PMCID: PMC4024836.
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PubMed Mentions:
87 Fields:
Translation:
HumansAnimalsCells
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Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis. J Clin Invest. 2013 Sep; 123(9):4023-35.
Humphreys BD, Xu F, Sabbisetti V, Grgic I, Movahedi Naini S, Wang N, Chen G, Xiao S, Patel D, Henderson JM, Ichimura T, Mou S, Soeung S, McMahon AP, Kuchroo VK, Bonventre JV. PMID: 23979159; PMCID: PMC3755983.
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PubMed Mentions:
159 Fields:
Translation:
AnimalsCells
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Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning. Development. 2013 Aug; 140(16):3423-34.
Holtz AM, Peterson KA, Nishi Y, Morin S, Song JY, Charron F, McMahon AP, Allen BL. PMID: 23900540; PMCID: PMC3737722.
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PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
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Wnt4/β-catenin signaling in medullary kidney myofibroblasts. J Am Soc Nephrol. 2013 Sep; 24(9):1399-412.
DiRocco DP, Kobayashi A, Taketo MM, McMahon AP, Humphreys BD. PMID: 23766539; PMCID: PMC3752942.
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PubMed Mentions:
87 Fields:
Translation:
AnimalsCells
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Filopodia: the cellular quills of hedgehog signaling? Dev Cell. 2013 May 28; 25(4):328-30.
McMahon AP, Hasso SM. PMID: 23725760.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Progenitor programming in mammalian nephrogenesis. Nephrology (Carlton). 2013 Mar; 18(3):177-9.
O'Brien LL, McMahon AP. PMID: 23279704; PMCID: PMC5862531.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Modeling recent human evolution in mice by expression of a selected EDAR variant. Cell. 2013 Feb 14; 152(4):691-702.
Kamberov YG, Wang S, Tan J, Gerbault P, Wark A, Tan L, Yang Y, Li S, Tang K, Chen H, Powell A, Itan Y, Fuller D, Lohmueller J, Mao J, Schachar A, Paymer M, Hostetter E, Byrne E, Burnett M, McMahon AP, Thomas MG, Lieberman DE, Jin L, Tabin CJ, Morgan BA, Sabeti PC. PMID: 23415220; PMCID: PMC3575602.
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PubMed Mentions:
113 Fields:
Translation:
HumansAnimalsCells
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Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat Commun. 2013; 4:1367.
Mae SI, Shono A, Shiota F, Yasuno T, Kajiwara M, Gotoda-Nishimura N, Arai S, Sato-Otubo A, Toyoda T, Takahashi K, Nakayama N, Cowan CA, Aoi T, Ogawa S, McMahon AP, Yamanaka S, Osafune K. PMID: 23340407; PMCID: PMC4447148.
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PubMed Mentions:
127 Fields:
Translation:
HumansAnimalsCells
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Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. Genes Dev. 2012 Dec 15; 26(24):2802-16.
Peterson KA, Nishi Y, Ma W, Vedenko A, Shokri L, Zhang X, McFarlane M, Baizabal JM, Junker JP, van Oudenaarden A, Mikkelsen T, Bernstein BE, Bailey TL, Bulyk ML, Wong WH, McMahon AP. PMID: 23249739; PMCID: PMC3533082.
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PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
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Germ cells are not required to establish the female pathway in mouse fetal gonads. PLoS One. 2012; 7(10):e47238.
Maatouk DM, Mork L, Hinson A, Kobayashi A, McMahon AP, Capel B. PMID: 23091613; PMCID: PMC3473035.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Front Neurosci. 2012; 6:130.
Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM. PMID: 22988430; PMCID: PMC3439845.
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PubMed Mentions:
15
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Glucocorticoid compounds modify smoothened localization and hedgehog pathway activity. Chem Biol. 2012 Aug 24; 19(8):972-82.
Wang Y, Davidow L, Arvanites AC, Blanchard J, Lam K, Xu K, Oza V, Yoo JW, Ng JM, Curran T, Rubin LL, McMahon AP. PMID: 22921064; PMCID: PMC3724998.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks. Dev Cell. 2012 Sep 11; 23(3):637-51.
Park JS, Ma W, O'Brien LL, Chung E, Guo JJ, Cheng JG, Valerius MT, McMahon JA, Wong WH, McMahon AP. PMID: 22902740; PMCID: PMC3892952.
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PubMed Mentions:
136 Fields:
Translation:
AnimalsCells
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Invasion of distal nephron precursors associates with tubular interconnection during nephrogenesis. J Am Soc Nephrol. 2012 Oct; 23(10):1682-90.
Kao RM, Vasilyev A, Miyawaki A, Drummond IA, McMahon AP. PMID: 22904347; PMCID: PMC3458467.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12592-7.
Guha A, Vasconcelos M, Cai Y, Yoneda M, Hinds A, Qian J, Li G, Dickel L, Johnson JE, Kimura S, Guo J, McMahon J, McMahon AP, Cardoso WV. PMID: 22797898; PMCID: PMC3412014.
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PubMed Mentions:
84 Fields:
Translation:
AnimalsCells
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Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation. ACS Chem Biol. 2012 Jun 15; 7(6):1040-8.
Wang Y, Arvanites AC, Davidow L, Blanchard J, Lam K, Yoo JW, Coy S, Rubin LL, McMahon AP. PMID: 22554036; PMCID: PMC3905677.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Identification of molecular compartments and genetic circuitry in the developing mammalian kidney. Development. 2012 May; 139(10):1863-73.
Yu J, Valerius MT, Duah M, Staser K, Hansard JK, Guo JJ, McMahon J, Vaughan J, Faria D, Georgas K, Rumballe B, Ren Q, Krautzberger AM, Junker JP, Thiagarajan RD, Machanick P, Gray PA, van Oudenaarden A, Rowitch DH, Stiles CD, Ma Q, Grimmond SM, Bailey TL, Little MH, McMahon AP. PMID: 22510988; PMCID: PMC3328182.
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PubMed Mentions:
34 Fields:
Translation:
Animals
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Mammalian kidney development: principles, progress, and projections. Cold Spring Harb Perspect Biol. 2012 May 01; 4(5).
Little MH, McMahon AP. PMID: 22550230; PMCID: PMC3331696.
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PubMed Mentions:
204 Fields:
Translation:
HumansCells
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The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis. Proc Natl Acad Sci U S A. 2012 Apr 24; 109(17):E1038-47.
Rajurkar M, De Jesus-Monge WE, Driscoll DR, Appleman VA, Huang H, Cotton JL, Klimstra DS, Zhu LJ, Simin K, Xu L, McMahon AP, Lewis BC, Mao J. PMID: 22493246; PMCID: PMC3340052.
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PubMed Mentions:
65 Fields:
Translation:
Animals
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Hedgehog-Gli pathway activation during kidney fibrosis. Am J Pathol. 2012 Apr; 180(4):1441-53.
Fabian SL, Penchev RR, St-Jacques B, Rao AN, Sipilä P, West KA, McMahon AP, Humphreys BD. PMID: 22342522; PMCID: PMC3349903.
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PubMed Mentions:
102 Fields:
Translation:
AnimalsCells
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Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice. Biol Reprod. 2012 Feb; 86(2):37.
Mork L, Maatouk DM, McMahon JA, Guo JJ, Zhang P, McMahon AP, Capel B. PMID: 21976597; PMCID: PMC3290667.
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PubMed Mentions:
103 Fields:
Translation:
AnimalsCells
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Signaling by SHH rescues facial defects following blockade in the brain. Dev Dyn. 2012 Feb; 241(2):247-56.
Chong HJ, Young NM, Hu D, Jeong J, McMahon AP, Hallgrimsson B, Marcucio RS. PMID: 22275045; PMCID: PMC3547623.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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An embryonic stem cell-based system for rapid analysis of transcriptional enhancers. Genesis. 2012 May; 50(5):443-50.
Tsanov KM, Nishi Y, Peterson KA, Liu J, Baetscher M, McMahon AP. PMID: 22083581; PMCID: PMC3334447.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells. Development. 2011 Oct; 138(19):4245-54.
Boyle SC, Kim M, Valerius MT, McMahon AP, Kopan R. PMID: 21852398; PMCID: PMC3171224.
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PubMed Mentions:
45 Fields:
Translation:
AnimalsCells
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The GUDMAP database--an online resource for genitourinary research. Development. 2011 Jul; 138(13):2845-53.
Harding SD, Armit C, Armstrong J, Brennan J, Cheng Y, Haggarty B, Houghton D, Lloyd-MacGilp S, Pi X, Roochun Y, Sharghi M, Tindal C, McMahon AP, Gottesman B, Little MH, Georgas K, Aronow BJ, Potter SS, Brunskill EW, Southard-Smith EM, Mendelsohn C, Baldock RA, Davies JA, Davidson D. PMID: 21652655; PMCID: PMC3188593.
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PubMed Mentions:
147 Fields:
Translation:
HumansAnimals
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Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function. Dev Cell. 2011 Jun 14; 20(6):775-87.
Allen BL, Song JY, Izzi L, Althaus IW, Kang JS, Charron F, Krauss RS, McMahon AP. PMID: 21664576; PMCID: PMC3121104.
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PubMed Mentions:
150 Fields:
Translation:
AnimalsCells
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Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation. Dev Cell. 2011 Jun 14; 20(6):788-801.
Izzi L, Lévesque M, Morin S, Laniel D, Wilkes BC, Mille F, Krauss RS, McMahon AP, Allen BL, Charron F. PMID: 21664577; PMCID: PMC3432913.
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PubMed Mentions:
133 Fields:
Translation:
AnimalsCells
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A low resistance microfluidic system for the creation of stable concentration gradients in a defined 3D microenvironment. Biomed Microdevices. 2010 Dec; 12(6):1027-41.
Amadi OC, Steinhauser ML, Nishi Y, Chung S, Kamm RD, McMahon AP, Lee RT. PMID: 20661647; PMCID: PMC3119200.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney. Kidney Int. 2011 Feb; 79(3):317-30.
Nagalakshmi VK, Ren Q, Pugh MM, Valerius MT, McMahon AP, Yu J. PMID: 20944551; PMCID: PMC3214622.
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PubMed Mentions:
92 Fields:
Translation:
AnimalsCells
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Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9736-41.
Lee EY, Ji H, Ouyang Z, Zhou B, Ma W, Vokes SA, McMahon AP, Wong WH, Scott MP. PMID: 20460306; PMCID: PMC2906878.
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PubMed Mentions:
64 Fields:
Translation:
AnimalsCells
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Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract. Development. 2010 May; 137(10):1721-9.
Mao J, Kim BM, Rajurkar M, Shivdasani RA, McMahon AP. PMID: 20430747; PMCID: PMC2860252.
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PubMed Mentions:
89 Fields:
Translation:
AnimalsCells
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Macrophage Wnt7b is critical for kidney repair and regeneration. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4194-9.
Lin SL, Li B, Rao S, Yeo EJ, Hudson TE, Nowlin BT, Pei H, Chen L, Zheng JJ, Carroll TJ, Pollard JW, McMahon AP, Lang RA, Duffield JS. PMID: 20160075; PMCID: PMC2840080.
View in:
PubMed Mentions:
217 Fields:
Translation:
AnimalsCells
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Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal. Genes Dev. 2010 Feb 01; 24(3):312-26.
Niakan KK, Ji H, Maehr R, Vokes SA, Rodolfa KT, Sherwood RI, Yamaki M, Dimos JT, Chen AE, Melton DA, McMahon AP, Eggan K. PMID: 20123909; PMCID: PMC2811832.
View in:
PubMed Mentions:
141 Fields:
Translation:
AnimalsCells
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Using mechanistic Bayesian networks to identify downstream targets of the sonic hedgehog pathway. BMC Bioinformatics. 2009 Dec 18; 10:433.
Shah A, Tenzen T, McMahon AP, Woolf PJ. PMID: 20021670; PMCID: PMC3087349.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol. 2010 Jan; 176(1):85-97.
Humphreys BD, Lin SL, Kobayashi A, Hudson TE, Nowlin BT, Bonventre JV, Valerius MT, McMahon AP, Duffield JS. PMID: 20008127; PMCID: PMC2797872.
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PubMed Mentions:
706 Fields:
Translation:
AnimalsCells
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An Hh-dependent pathway in lateral plate mesoderm enables the generation of left/right asymmetry. Curr Biol. 2009 Dec 01; 19(22):1912-7.
Tsiairis CD, McMahon AP. PMID: 19879143; PMCID: PMC2787870.
View in:
PubMed Mentions:
27 Fields:
Translation:
Animals
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Hedgehog signalling: Kif7 is not that fishy after all. Curr Biol. 2009 Sep 15; 19(17):R729-31.
Ingham PW, McMahon AP. PMID: 19906571.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population. Dev Biol. 2009 Sep 15; 333(2):312-23.
Mugford JW, Yu J, Kobayashi A, McMahon AP. PMID: 19591821; PMCID: PMC2748313.
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PubMed Mentions:
101 Fields:
Translation:
AnimalsCells
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Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Dev Biol. 2009 Aug 15; 332(2):273-86.
Georgas K, Rumballe B, Valerius MT, Chiu HS, Thiagarajan RD, Lesieur E, Aronow BJ, Brunskill EW, Combes AN, Tang D, Taylor D, Grimmond SM, Potter SS, McMahon AP, Little MH. PMID: 19501082.
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PubMed Mentions:
125 Fields:
Translation:
HumansAnimals
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Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell Stem Cell. 2009 Jun 05; 4(6):559-67.
Hofmann I, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Cornejo MG, Okabe R, Armstrong SA, Ghilardi N, Gould S, de Sauvage FJ, McMahon AP, Gilliland DG. PMID: 19497284; PMCID: PMC3065323.
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PubMed Mentions:
86 Fields:
Translation:
AnimalsCells
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Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb. Dev Cell. 2009 Apr; 16(4):600-6.
Mao J, McGlinn E, Huang P, Tabin CJ, McMahon AP. PMID: 19386268; PMCID: PMC3164484.
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PubMed Mentions:
73 Fields:
Translation:
AnimalsCells
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Modeling the spatio-temporal network that drives patterning in the vertebrate central nervous system. Biochim Biophys Acta. 2009 Apr; 1789(4):299-305.
Nishi Y, Ji H, Wong WH, McMahon AP, Vokes SA. PMID: 19445894.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Motor neurons with axial muscle projections specified by Wnt4/5 signaling. Neuron. 2009 Mar 12; 61(5):708-20.
Agalliu D, Takada S, Agalliu I, McMahon AP, Jessell TM. PMID: 19285468; PMCID: PMC2741579.
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PubMed Mentions:
62 Fields:
Translation:
AnimalsCells
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Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2623-8.
Wang Y, Zhou Z, Walsh CT, McMahon AP. PMID: 19196978; PMCID: PMC2650314.
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PubMed Mentions:
96 Fields:
Translation:
AnimalsCells
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A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney. Development. 2009 Jan; 136(1):161-71.
Yu J, Carroll TJ, Rajagopal J, Kobayashi A, Ren Q, McMahon AP. PMID: 19060336; PMCID: PMC2685965.
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PubMed Mentions:
128 Fields:
Translation:
AnimalsCells
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Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature. Science. 2008 Nov 21; 322(5905):1247-50.
Stenman JM, Rajagopal J, Carroll TJ, Ishibashi M, McMahon J, McMahon AP. PMID: 19023080.
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PubMed Mentions:
334 Fields:
Translation:
AnimalsCells
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Atlas of gene expression in the developing kidney at microanatomic resolution. Dev Cell. 2008 Nov; 15(5):781-91.
Brunskill EW, Aronow BJ, Georgas K, Rumballe B, Valerius MT, Aronow J, Kaimal V, Jegga AG, Yu J, Grimmond S, McMahon AP, Patterson LT, Little MH, Potter SS. PMID: 19000842; PMCID: PMC2653061.
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PubMed Mentions:
122 Fields:
Translation:
Animals
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Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways. Proc Natl Acad Sci U S A. 2008 Nov 04; 105(44):16976-81.
Wu JY, Purton LE, Rodda SJ, Chen M, Weinstein LS, McMahon AP, Scadden DT, Kronenberg HM. PMID: 18957542; PMCID: PMC2579363.
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PubMed Mentions:
118 Fields:
Translation:
AnimalsCells
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A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb. Genes Dev. 2008 Oct 01; 22(19):2651-63.
Vokes SA, Ji H, Wong WH, McMahon AP. PMID: 18832070; PMCID: PMC2559910.
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PubMed Mentions:
178 Fields:
Translation:
AnimalsCells
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Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney. Dev Biol. 2008 Dec 01; 324(1):88-98.
Mugford JW, Sipilä P, McMahon JA, McMahon AP. PMID: 18835385; PMCID: PMC2642884.
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PubMed Mentions:
153 Fields:
Translation:
AnimalsCells
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Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell. 2008 Aug 12; 14(2):123-34.
Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL. PMID: 18691547; PMCID: PMC2597270.
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PubMed Mentions:
346 Fields:
Translation:
HumansAnimalsCells
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Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell. 2008 Aug 07; 3(2):169-81.
Kobayashi A, Valerius MT, Mugford JW, Carroll TJ, Self M, Oliver G, McMahon AP. PMID: 18682239; PMCID: PMC2561900.
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PubMed Mentions:
493 Fields:
Translation:
AnimalsCells
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Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network. Development. 2008 Aug; 135(15):2489-503.
Dessaud E, McMahon AP, Briscoe J. PMID: 18621990.
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PubMed Mentions:
341 Fields:
Translation:
Animals
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Developmental biology. Grasping limb patterning. Science. 2008 Jul 18; 321(5887):350-2.
Tabin CJ, McMahon AP. PMID: 18635784.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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An eight residue fragment of an acyl carrier protein suffices for post-translational introduction of fluorescent pantetheinyl arms in protein modification in vitro and in vivo. J Am Chem Soc. 2008 Jul 30; 130(30):9925-30.
Zhou Z, Koglin A, Wang Y, McMahon AP, Walsh CT. PMID: 18593165; PMCID: PMC2561316.
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PubMed Mentions:
18 Fields:
Translation:
Cells
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Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease. Genes Dev. 2008 Jun 15; 22(12):1662-76.
Walkley CR, Qudsi R, Sankaran VG, Perry JA, Gostissa M, Roth SI, Rodda SJ, Snay E, Dunning P, Fahey FH, Alt FW, McMahon AP, Orkin SH. PMID: 18559481; PMCID: PMC2428063.
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PubMed Mentions:
209 Fields:
Translation:
HumansAnimals
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In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation. J Biol Chem. 2008 Jul 25; 283(30):21002-10.
Shimada M, Greer PA, McMahon AP, Bouxsein ML, Schipani E. PMID: 18515801; PMCID: PMC2475719.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Indian hedgehog signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye. Dev Biol. 2008 Aug 01; 320(1):242-55.
Dakubo GD, Mazerolle C, Furimsky M, Yu C, St-Jacques B, McMahon AP, Wallace VA. PMID: 18582859.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo. Dev Biol. 2008 Jul 15; 319(2):396-405.
Mugford JW, Sipilä P, Kobayashi A, Behringer RR, McMahon AP. PMID: 18485340; PMCID: PMC2580739.
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PubMed Mentions:
53 Fields:
Translation:
Animals
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Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme. Development. 2008 May; 135(9):1625-34.
Rajagopal J, Carroll TJ, Guseh JS, Bores SA, Blank LJ, Anderson WJ, Yu J, Zhou Q, McMahon AP, Melton DA. PMID: 18367557; PMCID: PMC2556060.
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PubMed Mentions:
94 Fields:
Translation:
AnimalsCells
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Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell. 2008 Mar 06; 2(3):284-91.
Humphreys BD, Valerius MT, Kobayashi A, Mugford JW, Soeung S, Duffield JS, McMahon AP, Bonventre JV. PMID: 18371453.
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PubMed Mentions:
400 Fields:
Translation:
AnimalsCells
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Disp1 regulates growth of mammalian long bones through the control of Ihh distribution. Dev Biol. 2008 May 15; 317(2):480-5.
Tsiairis CD, McMahon AP. PMID: 18395198; PMCID: PMC2430380.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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GUDMAP: the genitourinary developmental molecular anatomy project. J Am Soc Nephrol. 2008 Apr; 19(4):667-71.
McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P, GUDMAP project. PMID: 18287559.
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PubMed Mentions:
152 Fields:
Translation:
Animals
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Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning. Development. 2008 Mar; 135(6):1097-106.
Chamberlain CE, Jeong J, Guo C, Allen BL, McMahon AP. PMID: 18272593.
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PubMed Mentions:
98 Fields:
Translation:
AnimalsCells
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Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation. Gene Expr Patterns. 2008 May; 8(5):297-306.
Valerius MT, McMahon AP. PMID: 18346943; PMCID: PMC2435058.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Dicer-dependent pathways regulate chondrocyte proliferation and differentiation. Proc Natl Acad Sci U S A. 2008 Feb 12; 105(6):1949-54.
Kobayashi T, Lu J, Cobb BS, Rodda SJ, McMahon AP, Schipani E, Merkenschlager M, Kronenberg HM. PMID: 18238902; PMCID: PMC2538863.
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PubMed Mentions:
177 Fields:
Translation:
AnimalsCells
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Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state. Dev Biol. 2008 Feb 01; 314(1):112-26.
Marose TD, Merkel CE, McMahon AP, Carroll TJ. PMID: 18177851; PMCID: PMC2699621.
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PubMed Mentions:
80 Fields:
Translation:
AnimalsCells
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The cdx genes and retinoic acid control the positioning and segmentation of the zebrafish pronephros. PLoS Genet. 2007 Oct; 3(10):1922-38.
Wingert RA, Selleck R, Yu J, Song HD, Chen Z, Song A, Zhou Y, Thisse B, Thisse C, McMahon AP, Davidson AJ. PMID: 17953490; PMCID: PMC2042002.
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PubMed Mentions:
178 Fields:
Translation:
AnimalsCells
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Wnt3 signaling in the epiblast is required for proper orientation of the anteroposterior axis. Dev Biol. 2007 Dec 01; 312(1):312-20.
Barrow JR, Howell WD, Rule M, Hayashi S, Thomas KR, Capecchi MR, McMahon AP. PMID: 18028899.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen. Development. 2007 Oct; 134(20):3603-13.
Kim BM, Miletich I, Mao J, McMahon AP, Sharpe PA, Shivdasani RA. PMID: 17855428.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Nat Genet. 2007 Oct; 39(10):1225-34.
Zhou W, Lin L, Majumdar A, Li X, Zhang X, Liu W, Etheridge L, Shi Y, Martin J, Van de Ven W, Kaartinen V, Wynshaw-Boris A, McMahon AP, Rosenfeld MG, Evans SM. PMID: 17767158; PMCID: PMC5578467.
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PubMed Mentions:
89 Fields:
Translation:
HumansAnimalsCells
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Regulation of skeletogenic differentiation in cranial dermal bone. Development. 2007 Sep; 134(17):3133-44.
Abzhanov A, Rodda SJ, McMahon AP, Tabin CJ. PMID: 17670790.
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PubMed Mentions:
108 Fields:
Translation:
AnimalsCells
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Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development. Development. 2007 Jul; 134(13):2533-9.
Park JS, Valerius MT, McMahon AP. PMID: 17537789.
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PubMed Mentions:
191 Fields:
Translation:
AnimalsCells
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The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development. Genes Dev. 2007 May 15; 21(10):1244-57.
Allen BL, Tenzen T, McMahon AP. PMID: 17504941; PMCID: PMC1865495.
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PubMed Mentions:
143 Fields:
Translation:
AnimalsCells
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Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning. Development. 2007 May; 134(10):1977-89.
Vokes SA, Ji H, McCuine S, Tenzen T, Giles S, Zhong S, Longabaugh WJ, Davidson EH, Wong WH, McMahon AP. PMID: 17442700.
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PubMed Mentions:
164 Fields:
Translation:
AnimalsCells
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A high-resolution anatomical ontology of the developing murine genitourinary tract. Gene Expr Patterns. 2007 Jun; 7(6):680-99.
Little MH, Brennan J, Georgas K, Davies JA, Davidson DR, Baldock RA, Beverdam A, Bertram JF, Capel B, Chiu HS, Clements D, Cullen-McEwen L, Fleming J, Gilbert T, Herzlinger D, Houghton D, Kaufman MH, Kleymenova E, Koopman PA, Lewis AG, McMahon AP, Mendelsohn CL, Mitchell EK, Rumballe BA, Sweeney DE, Valerius MT, Yamada G, Yang Y, Yu J. PMID: 17452023; PMCID: PMC2117077.
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PubMed Mentions:
80 Fields:
Translation:
Animals
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Shifting paradigms in Hedgehog signaling. Curr Opin Cell Biol. 2007 Apr; 19(2):159-65.
Wang Y, McMahon AP, Allen BL. PMID: 17303409.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development. 2007 Feb; 134(4):801-11.
Cheng HT, Kim M, Valerius MT, Surendran K, Schuster-Gossler K, Gossler A, McMahon AP, Kopan R. PMID: 17229764; PMCID: PMC2613851.
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PubMed Mentions:
176 Fields:
Translation:
Animals
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Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Dev Cell. 2007 Jan; 12(1):99-112.
Gritli-Linde A, Hallberg K, Harfe BD, Reyahi A, Kannius-Janson M, Nilsson J, Cobourne MT, Sharpe PT, McMahon AP, Linde A. PMID: 17199044; PMCID: PMC1885956.
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PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
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Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation. Dev Cell. 2007 Jan; 12(1):113-27.
Tu X, Joeng KS, Nakayama KI, Nakayama K, Rajagopal J, Carroll TJ, McMahon AP, Long F. PMID: 17199045; PMCID: PMC1861818.
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PubMed Mentions:
146 Fields:
Translation:
AnimalsCells
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A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway. Cancer Res. 2006 Oct 15; 66(20):10171-8.
Mao J, Ligon KL, Rakhlin EY, Thayer SP, Bronson RT, Rowitch D, McMahon AP. PMID: 17047082; PMCID: PMC3806052.
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PubMed Mentions:
175 Fields:
Translation:
Animals
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Wnt9b is the mutated gene involved in multifactorial nonsyndromic cleft lip with or without cleft palate in A/WySn mice, as confirmed by a genetic complementation test. Birth Defects Res A Clin Mol Teratol. 2006 Aug; 76(8):574-9.
Juriloff DM, Harris MJ, McMahon AP, Carroll TJ, Lidral AC. PMID: 16998816.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimals
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Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors. Development. 2006 Aug; 133(16):3231-44.
Rodda SJ, McMahon AP. PMID: 16854976.
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PubMed Mentions:
532 Fields:
Translation:
AnimalsCells
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Control of transcription factor activity and osteoblast differentiation in mammalian cells using an evolved small-molecule-dependent intein. J Am Chem Soc. 2006 Jul 12; 128(27):8939-46.
Yuen CM, Rodda SJ, Vokes SA, McMahon AP, Liu DR. PMID: 16819890; PMCID: PMC2519127.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Independent regulation of skeletal growth by Ihh and IGF signaling. Dev Biol. 2006 Oct 01; 298(1):327-33.
Long F, Joeng KS, Xuan S, Efstratiadis A, McMahon AP. PMID: 16905129.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Reproducible and inducible knockdown of gene expression in mice. Genesis. 2006 May; 44(5):252-61.
Yu J, McMahon AP. PMID: 16676321.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice. Dev Cell. 2006 May; 10(5):647-56.
Tenzen T, Allen BL, Cole F, Kang JS, Krauss RS, McMahon AP. PMID: 16647304.
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PubMed Mentions:
178 Fields:
Translation:
AnimalsCells
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Retraction: Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse. Development. 2005 Dec; 132(24):5615.
McMahon AP, Tian H, Tenzen T. PMID: 16314492.
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PubMed Mentions: Fields:
-
BMP signaling stimulates cellular differentiation at multiple steps during cartilage development. Proc Natl Acad Sci U S A. 2005 Dec 13; 102(50):18023-7.
Kobayashi T, Lyons KM, McMahon AP, Kronenberg HM. PMID: 16322106; PMCID: PMC1312369.
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PubMed Mentions:
88 Fields:
Translation:
HumansAnimalsCells
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A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nat Genet. 2005 Dec; 37(12):1323-32.
Nybakken K, Vokes SA, Lin TY, McMahon AP, Perrimon N. PMID: 16311596; PMCID: PMC6429564.
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PubMed Mentions:
91 Fields:
Translation:
AnimalsCells
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An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo. Nucleic Acids Res. 2005 Oct 12; 33(18):e155.
Mao J, Barrow J, McMahon J, Vaughan J, McMahon AP. PMID: 16221970; PMCID: PMC1253836.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Binding hot spot for invasion inhibitory molecules on Plasmodium falciparum apical membrane antigen 1. Infect Immun. 2005 Oct; 73(10):6981-9.
Harris KS, Casey JL, Coley AM, Masciantonio R, Sabo JK, Keizer DW, Lee EF, McMahon A, Norton RS, Anders RF, Foley M. PMID: 16177378; PMCID: PMC1230972.
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PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
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Noggin antagonism of BMP4 signaling controls development of the axial skeleton in the mouse. Dev Biol. 2005 Oct 01; 286(1):149-57.
Wijgerde M, Karp S, McMahon J, McMahon AP. PMID: 16122729.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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Apoptosis induced by vitamin A signaling is crucial for connecting the ureters to the bladder. Nat Genet. 2005 Oct; 37(10):1082-9.
Batourina E, Tsai S, Lambert S, Sprenkle P, Viana R, Dutta S, Hensle T, Wang F, Niederreither K, McMahon AP, Carroll TJ, Mendelsohn CL. PMID: 16186816.
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PubMed Mentions:
69 Fields:
Translation:
AnimalsCells
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WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature. 2005 Sep 15; 437(7057):417-21.
Lobov IB, Rao S, Carroll TJ, Vallance JE, Ito M, Ondr JK, Kurup S, Glass DA, Patel MS, Shu W, Morrisey EE, McMahon AP, Karsenty G, Lang RA. PMID: 16163358; PMCID: PMC4259146.
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PubMed Mentions:
205 Fields:
Translation:
AnimalsCells
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Fate-mapping of the epithelial seam during palatal fusion rules out epithelial-mesenchymal transformation. Dev Biol. 2005 Sep 15; 285(2):490-5.
Vaziri Sani F, Hallberg K, Harfe BD, McMahon AP, Linde A, Gritli-Linde A. PMID: 16109396.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell. 2005 Aug; 9(2):283-92.
Carroll TJ, Park JS, Hayashi S, Majumdar A, McMahon AP. PMID: 16054034.
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PubMed Mentions:
386 Fields:
Translation:
AnimalsCells
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Neural crest origins of the neck and shoulder. Nature. 2005 Jul 21; 436(7049):347-55.
Matsuoka T, Ahlberg PE, Kessaris N, Iannarelli P, Dennehy U, Richardson WD, McMahon AP, Koentges G. PMID: 16034409; PMCID: PMC1352163.
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PubMed Mentions:
201 Fields:
Translation:
HumansAnimalsCells
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Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP. J Clin Invest. 2005 Jul; 115(7):1734-42.
Kobayashi T, Soegiarto DW, Yang Y, Lanske B, Schipani E, McMahon AP, Kronenberg HM. PMID: 15951842; PMCID: PMC1143590.
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PubMed Mentions:
107 Fields:
Translation:
AnimalsCells
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Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development. Development. 2005 Jun; 132(12):2809-23.
Kobayashi A, Kwan KM, Carroll TJ, McMahon AP, Mendelsohn CL, Behringer RR. PMID: 15930111.
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PubMed Mentions:
165 Fields:
Translation:
Animals
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Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005 May; 8(5):751-64.
Glass DA, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G. PMID: 15866165.
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PubMed Mentions:
652 Fields:
Translation:
AnimalsCells
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Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Dev Cell. 2005 Feb; 8(2):229-39.
Basson MA, Akbulut S, Watson-Johnson J, Simon R, Carroll TJ, Shakya R, Gross I, Martin GR, Lufkin T, McMahon AP, Wilson PD, Costantini FD, Mason IJ, Licht JD. PMID: 15691764.
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PubMed Mentions:
178 Fields:
Translation:
HumansAnimalsCells
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Mouse brain organization revealed through direct genome-scale TF expression analysis. Science. 2004 Dec 24; 306(5705):2255-7.
Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q. PMID: 15618518.
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PubMed Mentions:
236 Fields:
Translation:
Animals
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Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1. Development. 2005 Jan; 132(1):143-54.
Jeong J, McMahon AP. PMID: 15576403.
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PubMed Mentions:
97 Fields:
Translation:
AnimalsCells
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Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand. Development. 2005 Jan; 132(1):133-42.
Tian H, Jeong J, Harfe BD, Tabin CJ, McMahon AP. PMID: 15576405.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
-
Recent genetic studies of mouse kidney development. Curr Opin Genet Dev. 2004 Oct; 14(5):550-7.
Yu J, McMahon AP, Valerius MT. PMID: 15380247.
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PubMed Mentions:
42 Fields:
Translation:
Animals
-
Temporal requirement for hedgehog signaling in ventral telencephalic patterning. Development. 2004 Oct; 131(20):5031-40.
Fuccillo M, Rallu M, McMahon AP, Fishell G. PMID: 15371303.
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PubMed Mentions:
69 Fields:
Translation:
AnimalsCells
-
Hedgehog signaling: iguana debuts as a nuclear gatekeeper. Curr Biol. 2004 Aug 24; 14(16):R668-70.
Vokes SA, McMahon AP. PMID: 15324687.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell. 2004 Aug 20; 118(4):517-28.
Harfe BD, Scherz PJ, Nissim S, Tian H, McMahon AP, Tabin CJ. PMID: 15315763.
View in:
PubMed Mentions:
504 Fields:
Translation:
AnimalsCells
-
Hedgehog signaling is essential for endothelial tube formation during vasculogenesis. Development. 2004 Sep; 131(17):4371-80.
Vokes SA, Yatskievych TA, Heimark RL, McMahon J, McMahon AP, Antin PB, Krieg PA. PMID: 15294868.
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PubMed Mentions:
79 Fields:
Translation:
AnimalsCells
-
Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse. Development. 2004 Aug; 131(16):4021-33.
Tian H, Tenzen T, McMahon AP. PMID: 15269168.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells. Science. 2004 Jul 16; 305(5682):396-9.
Scherz PJ, Harfe BD, McMahon AP, Tabin CJ. PMID: 15256670.
View in:
PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
-
Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Dev Biol. 2004 Jun 15; 270(2):393-410.
Lewis PM, Gritli-Linde A, Smeyne R, Kottmann A, McMahon AP. PMID: 15183722.
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PubMed Mentions:
178 Fields:
Translation:
AnimalsCells
-
Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. J Clin Invest. 2004 Jun; 113(12):1692-700.
Rice R, Spencer-Dene B, Connor EC, Gritli-Linde A, McMahon AP, Dickson C, Thesleff I, Rice DP. PMID: 15199404; PMCID: PMC420504.
View in:
PubMed Mentions:
172 Fields:
Translation:
AnimalsCells
-
Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes Dev. 2004 Apr 15; 18(8):937-51.
Jeong J, Mao J, Tenzen T, Kottmann AH, McMahon AP. PMID: 15107405; PMCID: PMC395852.
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PubMed Mentions:
318 Fields:
Translation:
HumansAnimalsCells
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Derivation of embryonic stem-cell lines from human blastocysts. N Engl J Med. 2004 Mar 25; 350(13):1353-6.
Cowan CA, Klimanskaya I, McMahon J, Atienza J, Witmyer J, Zucker JP, Wang S, Morton CC, McMahon AP, Powers D, Melton DA. PMID: 14999088.
View in:
PubMed Mentions:
270 Fields:
Translation:
HumansCells
-
SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult. Dev Neurosci. 2004 Mar-Aug; 26(2-4):148-65.
Ellis P, Fagan BM, Magness ST, Hutton S, Taranova O, Hayashi S, McMahon A, Rao M, Pevny L. PMID: 15711057.
View in:
PubMed Mentions:
334 Fields:
Translation:
AnimalsCells
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Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development. 2004 Mar; 131(6):1309-18.
Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP. PMID: 14973297.
View in:
PubMed Mentions:
176 Fields:
Translation:
AnimalsCells
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Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science. 2003 Oct 03; 302(5642):113-7.
Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH, Julien JP, Goldstein LS, Cleveland DW. PMID: 14526083.
View in:
PubMed Mentions:
406 Fields:
Translation:
HumansAnimalsCells
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Maternal inheritance of Cre activity in a Sox2Cre deleter strain. Genesis. 2003 Oct; 37(2):51-3.
Hayashi S, Tenzen T, McMahon AP. PMID: 14595839.
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PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron. 2003 Sep 11; 39(6):937-50.
Machold R, Hayashi S, Rutlin M, Muzumdar MD, Nery S, Corbin JG, Gritli-Linde A, Dellovade T, Porter JA, Rubin LL, Dudek H, McMahon AP, Fishell G. PMID: 12971894.
View in:
PubMed Mentions:
267 Fields:
Translation:
AnimalsCells
-
Combined activities of hedgehog signaling inhibitors regulate pancreas development. Development. 2003 Oct; 130(20):4871-9.
Kawahira H, Ma NH, Tzanakakis ES, McMahon AP, Chuang PT, Hebrok M. PMID: 12917290.
View in:
PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
-
Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance. J Clin Invest. 2003 Aug; 112(4):554-65.
Rubera I, Loffing J, Palmer LG, Frindt G, Fowler-Jaeger N, Sauter D, Carroll T, McMahon A, Hummler E, Rossier BC. PMID: 12925696; PMCID: PMC171384.
View in:
PubMed Mentions:
69 Fields:
Translation:
AnimalsCells
-
Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development. Development. 2003 Jul; 130(13):2967-80.
Dakubo GD, Wang YP, Mazerolle C, Campsall K, McMahon AP, Wallace VA. PMID: 12756179.
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PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
-
Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Development. 2003 Jul; 130(14):3175-85.
Majumdar A, Vainio S, Kispert A, McMahon J, McMahon AP. PMID: 12783789.
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PubMed Mentions:
201 Fields:
Translation:
AnimalsCells
-
Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia. Development. 2003 May; 130(10):2275-87.
Ligon KL, Echelard Y, Assimacopoulos S, Danielian PS, Kaing S, Grove EA, McMahon AP, Rowitch DH. PMID: 12668639.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. EMBO J. 2003 Apr 15; 22(8):1811-23.
Trokovic R, Trokovic N, Hernesniemi S, Pirvola U, Vogt Weisenhorn DM, Rossant J, McMahon AP, Wurst W, Partanen J. PMID: 12682014; PMCID: PMC154461.
View in:
PubMed Mentions:
91 Fields:
Translation:
AnimalsCells
-
The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell. 2003 Apr 04; 113(1):11-23.
Charron F, Stein E, Jeong J, McMahon AP, Tessier-Lavigne M. PMID: 12679031.
View in:
PubMed Mentions:
260 Fields:
Translation:
AnimalsCells
-
Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev. 2003 Feb 01; 17(3):394-409.
Barrow JR, Thomas KR, Boussadia-Zahui O, Moore R, Kemler R, Capecchi MR, McMahon AP. PMID: 12569130; PMCID: PMC195987.
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PubMed Mentions:
107 Fields:
Translation:
AnimalsCells
-
Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung. Genes Dev. 2003 Feb 01; 17(3):342-7.
Chuang PT, Kawcak T, McMahon AP. PMID: 12569124; PMCID: PMC195990.
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PubMed Mentions:
132 Fields:
Translation:
AnimalsCells
-
Branching morphogenesis of the lung: new molecular insights into an old problem. Trends Cell Biol. 2003 Feb; 13(2):86-91.
Chuang PT, McMahon AP. PMID: 12559759.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Developmental roles and clinical significance of hedgehog signaling. Curr Top Dev Biol. 2003; 53:1-114.
McMahon AP, Ingham PW, Tabin CJ. PMID: 12509125.
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PubMed Mentions:
364 Fields:
Translation:
HumansAnimals
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Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Mech Dev. 2002 Dec; 119 Suppl 1:S97-S101.
Hayashi S, Lewis P, Pevny L, McMahon AP. PMID: 14516668.
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PubMed Mentions:
261 Fields:
Translation:
Animals
-
Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization. Development. 2002 Dec; 129(23):5323-37.
Gritli-Linde A, Bei M, Maas R, Zhang XM, Linde A, McMahon AP. PMID: 12403705.
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PubMed Mentions:
104 Fields:
Translation:
AnimalsCells
-
A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord. Genes Dev. 2002 Nov 15; 16(22):2849-64.
Wijgerde M, McMahon JA, Rule M, McMahon AP. PMID: 12435628; PMCID: PMC187482.
View in:
PubMed Mentions:
102 Fields:
Translation:
AnimalsCells
-
Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling. Development. 2002 Nov; 129(21):4963-74.
Rallu M, Machold R, Gaiano N, Corbin JG, McMahon AP, Fishell G. PMID: 12397105.
View in:
PubMed Mentions:
101 Fields:
Translation:
AnimalsCells
-
Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Gene Expr Patterns. 2002 Nov; 2(1-2):93-7.
Hayashi S, Lewis P, Pevny L, McMahon AP. PMID: 12617844.
View in:
PubMed Mentions:
73 Fields:
Translation:
AnimalsCells
-
Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development. 2002 Nov; 129(22):5301-12.
Yu J, Carroll TJ, McMahon AP. PMID: 12399320.
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PubMed Mentions:
222 Fields:
Translation:
AnimalsCells
-
A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo. Development. 2002 Oct; 129(20):4807-19.
Ishibashi M, McMahon AP. PMID: 12361972.
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PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
-
Cholesterol modification of Hedgehog family proteins. J Clin Invest. 2002 Sep; 110(5):591-6.
Jeong J, McMahon AP. PMID: 12208857; PMCID: PMC151115.
View in:
PubMed Mentions:
46 Fields:
Translation:
Animals
-
Development of normal retinal organization depends on Sonic hedgehog signaling from ganglion cells. Nat Neurosci. 2002 Sep; 5(9):831-2.
Wang YP, Dakubo G, Howley P, Campsall KD, Mazarolle CJ, Shiga SA, Lewis PM, McMahon AP, Wallace VA. PMID: 12195432.
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PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
-
Transient expression of the bHLH factor neurogenin-2 marks a subpopulation of neural crest cells biased for a sensory but not a neuronal fate. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8084-9.
Zirlinger M, Lo L, McMahon J, McMahon AP, Anderson DJ. PMID: 12060754; PMCID: PMC123024.
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PubMed Mentions:
62 Fields:
Translation:
AnimalsCells
-
A mitogen gradient of dorsal midline Wnts organizes growth in the CNS. Development. 2002 May; 129(9):2087-98.
Megason SG, McMahon AP. PMID: 11959819.
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PubMed Mentions:
269 Fields:
Translation:
HumansAnimalsCells
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Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol. 2002 Apr 15; 244(2):305-18.
Hayashi S, McMahon AP. PMID: 11944939.
View in:
PubMed Mentions:
792 Fields:
Translation:
Animals
-
Wnt-1 and Wnt-4 regulate thymic cellularity. Eur J Immunol. 2002 04; 32(4):967-71.
Mulroy T, McMahon JA, Burakoff SJ, McMahon AP, Sen J. PMID: 11920562.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
-
Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes. Mech Dev. 2002 Feb; 111(1-2):75-87.
Heanue TA, Davis RJ, Rowitch DH, Kispert A, McMahon AP, Mardon G, Tabin CJ. PMID: 11804780.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Hedgehog is required for murine yolk sac angiogenesis. Development. 2002 Jan; 129(2):361-72.
Byrd N, Becker S, Maye P, Narasimhaiah R, St-Jacques B, Zhang X, McMahon J, McMahon A, Grabel L. PMID: 11807029.
View in:
PubMed Mentions:
86 Fields:
Translation:
AnimalsCells
-
Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development. 2001 Dec; 128(24):5099-108.
Long F, Zhang XM, Karp S, Yang Y, McMahon AP. PMID: 11748145.
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PubMed Mentions:
322 Fields:
Translation:
AnimalsCells
-
Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 2001 Dec 01; 15(23):3059-87.
Ingham PW, McMahon AP. PMID: 11731473.
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PubMed Mentions:
1184 Fields:
Translation:
HumansAnimalsCells
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BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation. Development. 2001 Nov; 128(22):4523-34.
Minina E, Wenzel HM, Kreschel C, Karp S, Gaffield W, McMahon AP, Vortkamp A. PMID: 11714677.
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PubMed Mentions:
166 Fields:
Translation:
AnimalsCells
-
Wnt7b regulates placental development in mice. Dev Biol. 2001 Sep 15; 237(2):324-32.
Parr BA, Cornish VA, Cybulsky MI, McMahon AP. PMID: 11543617.
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PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
-
Alcohol hypersensitivity, increased locomotion, and spontaneous myoclonus in mice lacking the potassium channels Kv3.1 and Kv3.3. J Neurosci. 2001 Sep 01; 21(17):6657-65.
Espinosa F, McMahon A, Chan E, Wang S, Ho CS, Heintz N, Joho RH. PMID: 11517255; PMCID: PMC6763102.
View in:
PubMed Mentions:
36 Fields:
Translation:
Animals
-
The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides. Dev Biol. 2001 Aug 15; 236(2):364-86.
Gritli-Linde A, Lewis P, McMahon AP, Linde A. PMID: 11476578.
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PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
-
Dynamic interaction of S5 and S6 during voltage-controlled gating in a potassium channel. J Gen Physiol. 2001 Aug; 118(2):157-70.
Espinosa F, Fleischhauer R, McMahon A, Joho RH. PMID: 11479343; PMCID: PMC2233824.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node. Cell. 2001 Jul 27; 106(2):781-92.
Zhang XM, Ramalho-Santos M, McMahon AP. PMID: 11517919.
View in:
PubMed Mentions:
125 Fields:
Translation:
AnimalsCells
-
Developmental biology. Vesicles and the spinal cord. Nature. 2001 Jul 12; 412(6843):136-7.
Jeong J, McMahon AP. PMID: 11449254.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Six3 promotes the formation of ectopic optic vesicle-like structures in mouse embryos. Dev Dyn. 2001 Jul; 221(3):342-9.
Lagutin O, Zhu CC, Furuta Y, Rowitch DH, McMahon AP, Oliver G. PMID: 11458394.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
-
Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R asymmetry by the mouse node. Cell. 2001 Jun 15; 105(6):781-92.
Zhang XM, Ramalho-Santos M, McMahon AP. PMID: 11440720.
View in:
PubMed Mentions:
115 Fields:
Translation:
AnimalsCells
-
Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell. 2001 Jun 01; 105(5):599-612.
Lewis PM, Dunn MP, McMahon JA, Logan M, Martin JF, St-Jacques B, McMahon AP. PMID: 11389830.
View in:
PubMed Mentions:
180 Fields:
Translation:
AnimalsCells
-
Activation of expression of hedgehog target genes in basal cell carcinomas. J Invest Dermatol. 2001 May; 116(5):739-42.
Bonifas JM, Pennypacker S, Chuang PT, McMahon AP, Williams M, Rosenthal A, De Sauvage FJ, Epstein EH. PMID: 11348463.
View in:
PubMed Mentions:
58 Fields:
Translation:
HumansCells
-
Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development. 2001 Apr; 128(8):1253-64.
Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, McMahon AP, Sommer L, Boussadia O, Kemler R. PMID: 11262227.
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PubMed Mentions:
592 Fields:
Translation:
AnimalsCells
-
Hedgehog signaling is required for pituitary gland development. Development. 2001 Feb; 128(3):377-86.
Treier M, O'Connell S, Gleiberman A, Price J, Szeto DP, Burgess R, Chuang PT, McMahon AP, Rosenfeld MG. PMID: 11152636.
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PubMed Mentions:
81 Fields:
Translation:
AnimalsCells
-
Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development. J Clin Invest. 2001 Feb; 107(3):295-304.
Chung UI, Schipani E, McMahon AP, Kronenberg HM. PMID: 11160153; PMCID: PMC199199.
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PubMed Mentions:
141 Fields:
Translation:
AnimalsCells
-
Characterization of Pax-2 regulatory sequences that direct transgene expression in the Wolffian duct and its derivatives. Dev Biol. 2001 Jan 01; 229(1):128-40.
Kuschert S, Rowitch DH, Haenig B, McMahon AP, Kispert A. PMID: 11133159.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Regulation of pancreas development by hedgehog signaling. Development. 2000 Nov; 127(22):4905-13.
Hebrok M, Kim SK, St Jacques B, McMahon AP, Melton DA. PMID: 11044404.
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PubMed Mentions:
110 Fields:
Translation:
HumansAnimalsCells
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Sonic hedgehog regulates growth and morphogenesis of the tooth. Development. 2000 Nov; 127(22):4775-85.
Dassule HR, Lewis P, Bei M, Maas R, McMahon AP. PMID: 11044393.
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PubMed Mentions:
352 Fields:
Translation:
AnimalsCells
-
Secreted molecules in metanephric induction. J Am Soc Nephrol. 2000 Nov; 11 Suppl 16:S116-9.
Carroll TJ, McMahon AP. PMID: 11065341.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Neural patterning: the role of Nkx genes in the ventral spinal cord. Genes Dev. 2000 Sep 15; 14(18):2261-4.
McMahon AP. PMID: 10995382.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
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Localization of 17beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase isoform expression in the developing mouse testis--androstenedione is the major androgen secreted by fetal/neonatal leydig cells. Endocrinology. 2000 Jul; 141(7):2631-7.
O'Shaughnessy PJ, Baker PJ, Heikkilä M, Vainio S, McMahon AP. PMID: 10875268.
View in:
PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
-
Hedgehog signals regulate multiple aspects of gastrointestinal development. Development. 2000 Jun; 127(12):2763-72.
Ramalho-Santos M, Melton DA, McMahon AP. PMID: 10821773.
View in:
PubMed Mentions:
257 Fields:
Translation:
HumansAnimals
-
Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development. 2000 Apr; 127(8):1671-9.
Chai Y, Jiang X, Ito Y, Bringas P, Han J, Rowitch DH, Soriano P, McMahon AP, Sucov HM. PMID: 10725243.
View in:
PubMed Mentions:
616 Fields:
Translation:
Animals
-
A model for anteroposterior patterning of the vertebrate limb based on sequential long- and short-range Shh signalling and Bmp signalling. Development. 2000 Apr; 127(7):1337-48.
Drossopoulou G, Lewis KE, Sanz-Ezquerro JJ, Nikbakht N, McMahon AP, Hofmann C, Tickle C. PMID: 10704381.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
-
Fate of the mammalian cardiac neural crest. Development. 2000 Apr; 127(8):1607-16.
Jiang X, Rowitch DH, Soriano P, McMahon AP, Sucov HM. PMID: 10725237.
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PubMed Mentions:
497 Fields:
Translation:
Animals
-
Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes Dev. 2000 Mar 15; 14(6):650-4.
Brisken C, Heineman A, Chavarria T, Elenbaas B, Tan J, Dey SK, McMahon JA, McMahon AP, Weinberg RA. PMID: 10733525; PMCID: PMC316462.
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PubMed Mentions:
225 Fields:
Translation:
AnimalsCells
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The organizer factors Chordin and Noggin are required for mouse forebrain development. Nature. 2000 Feb 10; 403(6770):658-61.
Bachiller D, Klingensmith J, Kemp C, Belo JA, Anderson RM, May SR, McMahon JA, McMahon AP, Harland RM, Rossant J, De Robertis EM. PMID: 10688202.
View in:
PubMed Mentions:
156 Fields:
Translation:
Animals
-
Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron. 2000 Feb; 25(2):317-29.
Lu QR, Yuk D, Alberta JA, Zhu Z, Pawlitzky I, Chan J, McMahon AP, Stiles CD, Rowitch DH. PMID: 10719888.
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PubMed Mentions:
306 Fields:
Translation:
AnimalsCells
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A local Wnt-3a signal is required for development of the mammalian hippocampus. Development. 2000 Feb; 127(3):457-67.
Lee SM, Tole S, Grove E, McMahon AP. PMID: 10631167.
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PubMed Mentions:
207 Fields:
Translation:
AnimalsCells
-
Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways. Development. 2000 Feb; 127(3):543-8.
Karp SJ, Schipani E, St-Jacques B, Hunzelman J, Kronenberg H, McMahon AP. PMID: 10631175.
View in:
PubMed Mentions:
131 Fields:
Translation:
AnimalsCells
-
More surprises in the Hedgehog signaling pathway. Cell. 2000 Jan 21; 100(2):185-8.
McMahon AP. PMID: 10660040.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
-
T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes Dev. 1999 Dec 15; 13(24):3185-90.
Yamaguchi TP, Takada S, Yoshikawa Y, Wu N, McMahon AP. PMID: 10617567; PMCID: PMC317203.
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PubMed Mentions:
197 Fields:
Translation:
AnimalsCells
-
Pax-2 regulatory sequences that direct transgene expression in the developing neural plate and external granule cell layer of the cerebellum. Brain Res Dev Brain Res. 1999 Oct 20; 117(1):99-108.
Rowitch DH, Kispert A, McMahon AP. PMID: 10536237.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells. J Neurosci. 1999 Oct 15; 19(20):8954-65.
Rowitch DH, S-Jacques B, Lee SM, Flax JD, Snyder EY, McMahon AP. PMID: 10516314; PMCID: PMC6782773.
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PubMed Mentions:
110 Fields:
Translation:
AnimalsCells
-
Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds. Nature. 1999 Oct 07; 401(6753):598-602.
Zúñiga A, Haramis AP, McMahon AP, Zeller R. PMID: 10524628.
View in:
PubMed Mentions:
135 Fields:
Translation:
HumansAnimalsCells
-
Schwann Cell-Derived Desert Hedgehog Signals Nerve Sheath Formation. Ann N Y Acad Sci. 1999 Oct; 883(1):196-202.
Mirsky R, Parmantier E, McMahon AP, Jessen KR. PMID: 29086927.
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PubMed Mentions:
2 Fields:
-
Schwann cell-derived desert hedgehog signals nerve sheath formation. Ann N Y Acad Sci. 1999 Sep 14; 883:196-202.
Mirsky R, Parmantier E, McMahon AP, Jessen KR. PMID: 10586245.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev. 1999 Aug 15; 13(16):2072-86.
St-Jacques B, Hammerschmidt M, McMahon AP. PMID: 10465785; PMCID: PMC316949.
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PubMed Mentions:
642 Fields:
Translation:
AnimalsCells
-
Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths. Neuron. 1999 Aug; 23(4):713-24.
Parmantier E, Lynn B, Lawson D, Turmaine M, Namini SS, Chakrabarti L, McMahon AP, Jessen KR, Mirsky R. PMID: 10482238.
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PubMed Mentions:
106 Fields:
Translation:
AnimalsCells
-
Noggin is a mesenchymally derived stimulator of hair-follicle induction. Nat Cell Biol. 1999 Jul; 1(3):158-64.
Botchkarev VA, Botchkareva NV, Roth W, Nakamura M, Chen LH, Herzog W, Lindner G, McMahon JA, Peters C, Lauster R, McMahon AP, Paus R. PMID: 10559902.
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PubMed Mentions:
147 Fields:
Translation:
Animals
-
Cystic malformation of the posterior cerebellar vermis in transgenic mice that ectopically express Engrailed-1, a homeodomain transcription factor. Teratology. 1999 Jul; 60(1):22-8.
Rowitch DH, Danielian PS, McMahon AP, Zec N. PMID: 10413335.
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PubMed Mentions:
5 Fields:
Translation:
Animals
-
Modulation of early but not later stages of programmed cell death in embryonic avian spinal cord by sonic hedgehog. Mol Cell Neurosci. 1999 May; 13(5):348-61.
Oppenheim RW, Homma S, Marti E, Prevette D, Wang S, Yaginuma H, McMahon AP. PMID: 10356297.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Negative feedback mechanisms and their roles during pattern formation. Cell. 1999 Apr 02; 97(1):13-6.
Perrimon N, McMahon AP. PMID: 10199398.
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PubMed Mentions:
29 Fields:
Translation:
Animals
-
A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development. 1999 Mar; 126(6):1211-23.
Yamaguchi TP, Bradley A, McMahon AP, Jones S. PMID: 10021340.
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PubMed Mentions:
397 Fields:
Translation:
AnimalsCells
-
Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein. Nature. 1999 Feb 18; 397(6720):617-21.
Chuang PT, McMahon AP. PMID: 10050855.
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PubMed Mentions:
279 Fields:
Translation:
AnimalsCells
-
Female development in mammals is regulated by Wnt-4 signalling. Nature. 1999 Feb 04; 397(6718):405-9.
Vainio S, Heikkilä M, Kispert A, Chin N, McMahon AP. PMID: 9989404.
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PubMed Mentions:
375 Fields:
Translation:
AnimalsCells
-
"Cre"-ating mouse mutants-a meeting review on conditional mouse genetics. Genes Dev. 1999 Jan 15; 13(2):142-5.
Rossant J, McMahon A. PMID: 9925637.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
-
Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and -independent mechanisms. Development. 1999 Jan; 126(2):281-92.
Epstein DJ, McMahon AP, Joyner AL. PMID: 9847242.
View in:
PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
-
Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells. J Biol Chem. 1999 Jan 01; 274(1):129-34.
Li L, Yuan H, Xie W, Mao J, Caruso AM, McMahon A, Sussman DJ, Wu D. PMID: 9867820.
View in:
PubMed Mentions:
97 Fields:
Translation:
AnimalsCells
-
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr Biol. 1998 Dec 03; 8(24):1323-6.
Danielian PS, Muccino D, Rowitch DH, Michael SK, McMahon AP. PMID: 9843687.
View in:
PubMed Mentions:
709 Fields:
Translation:
AnimalsCells
-
Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development. 1998 Nov; 125(21):4225-34.
Kispert A, Vainio S, McMahon AP. PMID: 9753677.
View in:
PubMed Mentions:
158 Fields:
Translation:
AnimalsCells
-
Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a. Nature. 1998 Oct 15; 395(6703):707-10.
Parr BA, McMahon AP. PMID: 9790192.
View in:
PubMed Mentions:
109 Fields:
Translation:
Animals
-
Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Dev Biol. 1998 Oct 15; 202(2):215-27.
Dassule HR, McMahon AP. PMID: 9769173.
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PubMed Mentions:
93 Fields:
Translation:
AnimalsCells
-
The classical mouse mutant postaxial hemimelia results from a mutation in the Wnt 7a gene. Dev Biol. 1998 Oct 15; 202(2):228-34.
Parr BA, Avery EJ, Cygan JA, McMahon AP. PMID: 9769174.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Inhibitory action of BMPs on Pax1 expression and on shoulder girdle formation during limb development. Dev Dyn. 1998 Oct; 213(2):199-206.
Hofmann C, Drossopoulou G, McMahon A, Balling R, Tickle C. PMID: 9786420.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Sonic hedgehog signaling is essential for hair development. Curr Biol. 1998 Sep 24; 8(19):1058-68.
St-Jacques B, Dassule HR, Karavanova I, Botchkarev VA, Li J, Danielian PS, McMahon JA, Lewis PM, Paus R, McMahon AP. PMID: 9768360.
View in:
PubMed Mentions:
268 Fields:
Translation:
AnimalsCells
-
Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Curr Biol. 1998 Sep 24; 8(19):1083-6.
Pepicelli CV, Lewis PM, McMahon AP. PMID: 9768363.
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PubMed Mentions:
226 Fields:
Translation:
Animals
-
Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling. Development. 1998 Aug; 125(16):3123-32.
Yang Y, Guillot P, Boyd Y, Lyon MF, McMahon AP. PMID: 9671585.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
Identification of an evolutionarily conserved 110 base-pair cis-acting regulatory sequence that governs Wnt-1 expression in the murine neural plate. Development. 1998 Jul; 125(14):2735-46.
Rowitch DH, Echelard Y, Danielian PS, Gellner K, Brenner S, McMahon AP. PMID: 9636087.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
FGF is an essential regulator of the fifth cell division in preimplantation mouse embryos. Dev Biol. 1998 Jun 01; 198(1):105-15.
Chai N, Patel Y, Jacobson K, McMahon J, McMahon A, Rappolee DA. PMID: 9640334.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
-
Multistep signaling requirements for pituitary organogenesis in vivo. Genes Dev. 1998 Jun 01; 12(11):1691-704.
Treier M, Gleiberman AS, O'Connell SM, Szeto DP, McMahon JA, McMahon AP, Rosenfeld MG. PMID: 9620855; PMCID: PMC316866.
View in:
PubMed Mentions:
126 Fields:
Translation:
AnimalsCells
-
Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton. Science. 1998 May 29; 280(5368):1455-7.
Brunet LJ, McMahon JA, McMahon AP, Harland RM. PMID: 9603738.
View in:
PubMed Mentions:
221 Fields:
Translation:
AnimalsCells
-
Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev. 1998 May 15; 12(10):1438-52.
McMahon JA, Takada S, Zimmerman LB, Fan CM, Harland RM, McMahon AP. PMID: 9585504; PMCID: PMC316831.
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PubMed Mentions:
243 Fields:
Translation:
Animals
-
The effect of pertussis toxin on zebrafish development: a possible role for inhibitory G-proteins in hedgehog signaling. Dev Biol. 1998 Feb 15; 194(2):166-71.
Hammerschmidt M, McMahon AP. PMID: 9501021.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
-
Calbindin-D28k buffers intracellular calcium and promotes resistance to degeneration in PC12 cells. Brain Res Mol Brain Res. 1998 Feb; 54(1):56-63.
McMahon A, Wong BS, Iacopino AM, Ng MC, Chi S, German DC. PMID: 9526044.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
A 5.5-kb enhancer is both necessary and sufficient for regulation of Wnt-1 transcription in vivo. Dev Biol. 1997 Dec 15; 192(2):300-9.
Danielian PS, Echelard Y, Vassileva G, McMahon AP. PMID: 9441669.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Calbindin-D28k in nerve cell nuclei. Neuroscience. 1997 Dec; 81(3):735-43.
German DC, Ng MC, Liang CL, McMahon A, Iacopino AM. PMID: 9316025.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants. Development. 1997 Dec; 124(24):5021-32.
Cygan JA, Johnson RL, McMahon AP. PMID: 9362463.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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GDNF induces branching and increased cell proliferation in the ureter of the mouse. Dev Biol. 1997 Dec 01; 192(1):193-8.
Pepicelli CV, Kispert A, Rowitch DH, McMahon AP. PMID: 9405108.
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PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
-
Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb. Development. 1997 Nov; 124(21):4393-404.
Yang Y, Drossopoulou G, Chuang PT, Duprez D, Marti E, Bumcrot D, Vargesson N, Clarke J, Niswander L, McMahon A, Tickle C. PMID: 9334287.
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PubMed Mentions:
73 Fields:
Translation:
AnimalsCells
-
Recent advances in hedgehog signalling. Trends Cell Biol. 1997 Nov; 7(11):442-6.
Tabin CJ, McMahon AP. PMID: 17709003.
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PubMed Mentions:
12 Fields:
-
Wnt signalling required for expansion of neural crest and CNS progenitors. Nature. 1997 Oct 30; 389(6654):966-70.
Ikeya M, Lee SM, Johnson JE, McMahon AP, Takada S. PMID: 9353119.
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PubMed Mentions:
210 Fields:
Translation:
AnimalsCells
-
Dopamine transporter mRNA levels are high in midbrain neurons vulnerable to MPTP. Neuroreport. 1997 Oct 20; 8(15):3327-31.
Sanghera MK, Manaye K, McMahon A, Sonsalla PK, German DC. PMID: 9351666.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
A role for Indian hedgehog in extraembryonic endoderm differentiation in F9 cells and the early mouse embryo. Dev Biol. 1997 Jul 15; 187(2):298-310.
Becker S, Wang ZJ, Massey H, Arauz A, Labosky P, Hammerschmidt M, St-Jacques B, Bumcrot D, McMahon A, Grabel L. PMID: 9242425.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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The zebrafish organizer requires chordino. Nature. 1997 Jun 26; 387(6636):862-3.
Schulte-Merker S, Lee KJ, McMahon AP, Hammerschmidt M. PMID: 9202118.
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PubMed Mentions:
102 Fields:
Translation:
AnimalsCells
-
Analysis of neural crest cell migration in Splotch mice using a neural crest-specific LacZ reporter. Dev Biol. 1997 May 15; 185(2):139-47.
Serbedzija GN, McMahon AP. PMID: 9187079.
View in:
PubMed Mentions:
22 Fields:
Translation:
Animals
-
Evidence that absence of Wnt-3a signaling promotes neuralization instead of paraxial mesoderm development in the mouse. Dev Biol. 1997 Mar 15; 183(2):234-42.
Yoshikawa Y, Fujimori T, McMahon AP, Takada S. PMID: 9126297.
View in:
PubMed Mentions:
99 Fields:
Translation:
AnimalsCells
-
Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development. 1997 Mar; 124(5):959-69.
Lee SM, Danielian PS, Fritzsch B, McMahon AP. PMID: 9056772.
View in:
PubMed Mentions:
67 Fields:
Translation:
AnimalsCells
-
Cell interactions in patterning the mammalian midbrain. Cold Spring Harb Symp Quant Biol. 1997; 62:535-44.
Rowitch DH, Danielian PS, Lee SM, Echelard Y, McMahon AP. PMID: 9598387.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Wnt5 is required for tail formation in the zebrafish embryo. Cold Spring Harb Symp Quant Biol. 1997; 62:227-34.
Rauch GJ, Hammerschmidt M, Blader P, Schauerte HE, Strähle U, Ingham PW, McMahon AP, Haffter P. PMID: 9598355.
View in:
PubMed Mentions:
72 Fields:
Translation:
AnimalsCells
-
The world according to hedgehog. Trends Genet. 1997 Jan; 13(1):14-21.
Hammerschmidt M, Brook A, McMahon AP. PMID: 9009843.
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PubMed Mentions:
103 Fields:
Translation:
HumansAnimalsCells
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Assignment of WNT7B to human chromosome band 22q13 by in situ hybridization. Cytogenet Cell Genet. 1997; 77(3-4):288-9.
van Bokhoven H, Kissing J, Schepens M, van Beersum S, Simons A, Riegman P, McMahon JA, McMahon AP, Brunner HG. PMID: 9284940.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Genes from zebrafish screens. Nature. 1996 Dec 12; 384(6609):515-6.
Holder N, McMahon A. PMID: 8955264.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Hedgehogs in the clinic. Nat Med. 1996 Dec; 2(12):1308-10.
McMahon AP, Chuang PT. PMID: 8946825.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
-
Calbindin-D28K in the nucleus of nerve growth factor-treated PC12 cells. Neuroreport. 1996 Nov 04; 7(15-17):2419-22.
McMahon A, Lephart ED, Chi S, Lee M, Iacopino AM, German DC. PMID: 8981395.
View in:
PubMed Mentions: Fields:
Translation:
AnimalsCells
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Cell death in the CNS of the Wnt-1 mutant mouse. J Neurobiol. 1996 Nov; 31(3):275-82.
Serbedzija GN, Dickinson M, McMahon AP. PMID: 8910786.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips. Development. 1996 Nov; 122(11):3627-37.
Kispert A, Vainio S, Shen L, Rowitch DH, McMahon AP. PMID: 8951078.
View in:
PubMed Mentions:
78 Fields:
Translation:
AnimalsCells
-
Early deletion of neuromeres in Wnt-1-/- mutant mice: evaluation by morphological and molecular markers. J Comp Neurol. 1996 Oct 14; 374(2):246-58.
Mastick GS, Fan CM, Tessier-Lavigne M, Serbedzija GN, McMahon AP, Easter SS. PMID: 8906497.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor. Genes Dev. 1996 Oct 01; 10(19):2452-61.
Hammerschmidt M, Serbedzija GN, McMahon AP. PMID: 8843197.
View in:
PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
-
Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development. Nature. 1996 Sep 26; 383(6598):332-4.
Danielian PS, McMahon AP. PMID: 8848044.
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PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
-
Antagonizing cAMP-dependent protein kinase A in the dorsal CNS activates a conserved Sonic hedgehog signaling pathway. Development. 1996 Sep; 122(9):2885-94.
Epstein DJ, Marti E, Scott MP, McMahon AP. PMID: 8787761.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Early mouse development: lessons from gene targeting. Curr Opin Genet Dev. 1996 Aug; 6(4):439-44.
St-Jacques B, McMahon AP. PMID: 8791525.
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PubMed Mentions:
6 Fields:
Translation:
Animals
-
Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2. Nature. 1996 May 16; 381(6579):238-41.
Zhang J, Hagopian-Donaldson S, Serbedzija G, Elsemore J, Plehn-Dujowich D, McMahon AP, Flavell RA, Williams T. PMID: 8622766.
View in:
PubMed Mentions:
183 Fields:
Translation:
Animals
-
Cloning and characterization of cDNAs for novel proteins with glutamic acid-proline dipeptide tandem repeats. Biochim Biophys Acta. 1996 May 02; 1306(2-3):147-52.
Geertman R, McMahon A, Sabban EL. PMID: 8634331.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. Genes Dev. 1996 Mar 15; 10(6):647-58.
Hammerschmidt M, Bitgood MJ, McMahon AP. PMID: 8598293.
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PubMed Mentions:
96 Fields:
Translation:
AnimalsCells
-
Sertoli cell signaling by Desert hedgehog regulates the male germline. Curr Biol. 1996 Mar 01; 6(3):298-304.
Bitgood MJ, Shen L, McMahon AP. PMID: 8805249.
View in:
PubMed Mentions:
190 Fields:
Translation:
AnimalsCells
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Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development. Genes Dev. 1996 Feb 01; 10(3):313-24.
Greco TL, Takada S, Newhouse MM, McMahon JA, McMahon AP, Camper SA. PMID: 8595882.
View in:
PubMed Mentions:
78 Fields:
Translation:
AnimalsCells
-
Sonic hedgehog: making the gradient. Chem Biol. 1996 Jan; 3(1):13-6.
Bumcrot DA, McMahon AP. PMID: 8807822.
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PubMed Mentions:
2 Fields:
Translation:
Cells
-
Induction of adrenal tyrosine hydroxylase mRNA by single immobilization stress occurs even after splanchnic transection and in the presence of cholinergic antagonists. J Neurochem. 1996 Jan; 66(1):138-46.
Kvetnanský R, Nankova B, Hiremagalur B, Viskupic E, Vietor I, Rusnak M, McMahon A, Kopin IJ, Sabban EL. PMID: 8522945.
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PubMed Mentions:
3 Fields:
Translation:
Animals
-
Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite. Genes Dev. 1995 Dec 01; 9(23):2911-22.
Münsterberg AE, Kitajewski J, Bumcrot DA, McMahon AP, Lassar AB. PMID: 7498788.
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PubMed Mentions:
111 Fields:
Translation:
AnimalsCells
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Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol. 1995 Nov; 172(1):126-38.
Bitgood MJ, McMahon AP. PMID: 7589793.
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PubMed Mentions:
333 Fields:
Translation:
AnimalsCells
-
Induction of dopaminergic neuron phenotype in the midbrain by Sonic hedgehog protein. Nat Med. 1995 Nov; 1(11):1184-8.
Wang MZ, Jin P, Bumcrot DA, Marigo V, McMahon AP, Wang EA, Woolf T, Pang K. PMID: 7584992.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties. Exp Cell Res. 1995 Oct; 220(2):363-73.
Burrus LW, McMahon AP. PMID: 7556445.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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A single homeodomain binding site restricts spatial expression of Wnt-1 in the developing brain. Mech Dev. 1995 Sep; 53(1):87-96.
Iler N, Rowitch DH, Echelard Y, McMahon AP, Abate-Shen C. PMID: 8555114.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
Distribution of Sonic hedgehog peptides in the developing chick and mouse embryo. Development. 1995 Aug; 121(8):2537-47.
Martí E, Takada R, Bumcrot DA, Sasaki H, McMahon AP. PMID: 7671817.
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PubMed Mentions:
70 Fields:
Translation:
Animals
-
Development of midbrain and anterior hindbrain ocular motoneurons in normal and Wnt-1 knockout mice. J Neurobiol. 1995 Aug; 27(4):457-69.
Fritzsch B, Nichols DH, Echelard Y, McMahon AP. PMID: 7561827.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Wnt expression patterns in chick embryo nervous system. Mech Dev. 1995 Jul; 52(1):9-25.
Hollyday M, McMahon JA, McMahon AP. PMID: 7577679.
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PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
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Dorsalization of the neural tube by the non-neural ectoderm. Development. 1995 Jul; 121(7):2099-106.
Dickinson ME, Selleck MA, McMahon AP, Bronner-Fraser M. PMID: 7635055.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1. Mech Dev. 1995 Jul; 52(1):3-8.
Rowitch DH, McMahon AP. PMID: 7577673.
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PubMed Mentions:
24 Fields:
Translation:
Animals
-
Somite differentiation. Sonic signals somites. Curr Biol. 1995 Jun 01; 5(6):612-4.
Bumcrot DA, McMahon AP. PMID: 7552169.
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PubMed Mentions:
17 Fields:
Translation:
Animals
-
Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants. Nature. 1995 May 25; 375(6529):322-5.
Martí E, Bumcrot DA, Takada R, McMahon AP. PMID: 7753196.
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PubMed Mentions:
103 Fields:
Translation:
AnimalsCells
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Proteolytic processing yields two secreted forms of sonic hedgehog. Mol Cell Biol. 1995 Apr; 15(4):2294-303.
Bumcrot DA, Takada R, McMahon AP. PMID: 7891723; PMCID: PMC230457.
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PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature. 1995 Mar 23; 374(6520):350-3.
Parr BA, McMahon AP. PMID: 7885472.
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PubMed Mentions:
124 Fields:
Translation:
AnimalsCells
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Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature. 1994 Dec 15; 372(6507):679-83.
Stark K, Vainio S, Vassileva G, McMahon AP. PMID: 7990960.
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PubMed Mentions:
327 Fields:
Translation:
AnimalsCells
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Mouse development. Winged-helix in axial patterning. Curr Biol. 1994 Oct 01; 4(10):903-6.
McMahon AP. PMID: 7850424.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
Differential transformation of mammary epithelial cells by Wnt genes. Mol Cell Biol. 1994 Sep; 14(9):6278-86.
Wong GT, Gavin BJ, McMahon AP. PMID: 8065359; PMCID: PMC359154.
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PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
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Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS. Development. 1994 Aug; 120(8):2213-24.
Echelard Y, Vassileva G, McMahon AP. PMID: 7925022.
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PubMed Mentions:
110 Fields:
Translation:
AnimalsCells
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Wnt-1-dependent regulation of local E-cadherin and alpha N-catenin expression in the embryonic mouse brain. Development. 1994 Aug; 120(8):2225-34.
Shimamura K, Hirano S, McMahon AP, Takeichi M. PMID: 7925023.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
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Experimental control of axial pattern in the chick blastoderm by local expression of Wnt and activin: the role of HNK-1 positive cells. Dev Biol. 1994 Aug; 164(2):513-27.
Cooke J, Takada S, McMahon A. PMID: 7519156.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Wnt genes and vertebrate development. Curr Opin Genet Dev. 1994 Aug; 4(4):523-8.
Parr BA, McMahon AP. PMID: 7950319.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Induction of tyrosine hydroxylase gene expression by a nonneuronal nonpituitary-mediated mechanism in immobilization stress. Proc Natl Acad Sci U S A. 1994 Jun 21; 91(13):5937-41.
Nankova B, Kvetnanský R, McMahon A, Viskupic E, Hiremagalur B, Frankle G, Fukuhara K, Kopin IJ, Sabban EL. PMID: 7912437; PMCID: PMC44112.
View in:
PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous system. Development. 1994 Jun; 120(6):1453-71.
Dickinson ME, Krumlauf R, McMahon AP. PMID: 8050356.
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PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
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Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue. Cancer Res. 1994 May 15; 54(10):2615-21.
Huguet EL, McMahon JA, McMahon AP, Bicknell R, Harris AL. PMID: 8168088.
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72 Fields:
Translation:
HumansCells
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DNA affinity cleaving analysis of homeodomain-DNA interaction: identification of homeodomain consensus sites in genomic DNA. Proc Natl Acad Sci U S A. 1994 Jan 04; 91(1):118-22.
Shang Z, Ebright YW, Iler N, Pendergrast PS, Echelard Y, McMahon AP, Ebright RH, Abate C. PMID: 7904065; PMCID: PMC42897.
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PubMed Mentions:
10 Fields:
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AnimalsCells
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Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors. Neuron. 1994 Jan; 12(1):11-24.
Zimmerman L, Parr B, Lendahl U, Cunningham M, McKay R, Gavin B, Mann J, Vassileva G, McMahon A. PMID: 8292356.
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PubMed Mentions:
222 Fields:
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AnimalsCells
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Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev. 1994 Jan; 8(2):174-89.
Takada S, Stark KL, Shea MJ, Vassileva G, McMahon JA, McMahon AP. PMID: 8299937.
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PubMed Mentions:
224 Fields:
Translation:
AnimalsCells
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The hedgehog gene family in Drosophila and vertebrate development. Dev Suppl. 1994; 43-51.
Fietz MJ, Concordet JP, Barbosa R, Johnson R, Krauss S, McMahon AP, Tabin C, Ingham PW. PMID: 7579523.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell. 1993 Dec 31; 75(7):1417-30.
Echelard Y, Epstein DJ, St-Jacques B, Shen L, Mohler J, McMahon JA, McMahon AP. PMID: 7916661.
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PubMed Mentions:
591 Fields:
Translation:
AnimalsCells
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Wnt family proteins are secreted and associated with the cell surface. Mol Biol Cell. 1993 Dec; 4(12):1267-75.
Smolich BD, McMahon JA, McMahon AP, Papkoff J. PMID: 8167409; PMCID: PMC275763.
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PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
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Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development. 1993 Sep; 119(1):247-61.
Parr BA, Shea MJ, Vassileva G, McMahon AP. PMID: 8275860.
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PubMed Mentions:
184 Fields:
Translation:
Animals
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Cell signalling in induction and anterior-posterior patterning of the vertebrate central nervous system. Curr Opin Neurobiol. 1993 Feb; 3(1):4-7.
McMahon AP. PMID: 8453288.
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PubMed Mentions:
1 Fields:
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AnimalsCells
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Cloning developmentally regulated gene families. Methods Enzymol. 1993; 225:653-63.
Gavin BJ, McMahon AP. PMID: 8231877.
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AnimalsCells
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Factors influencing frequency production of transgenic mice. Methods Enzymol. 1993; 225:771-81.
Mann JR, McMahon AP. PMID: 8231885.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Regulation of expression of dopamine beta-hydroxylase in PC12 cells by glucocorticoids and cyclic AMP analogues. J Neurochem. 1992 Dec; 59(6):2040-7.
McMahon A, Sabban EL. PMID: 1359011.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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The role of Wnt genes in vertebrate development. Curr Opin Genet Dev. 1992 Aug; 2(4):562-6.
Dickinson ME, McMahon AP. PMID: 1388080.
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PubMed Mentions:
17 Fields:
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AnimalsCells
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Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development. 1992 Jul; 115(3):737-44.
Del Amo FF, Smith DE, Swiatek PJ, Gendron-Maguire M, Greenspan RJ, McMahon AP, Gridley T. PMID: 1425352.
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PubMed Mentions:
52 Fields:
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AnimalsCells
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Regulation of tyrosine hydroxylase and dopamine beta-hydroxylase mRNA levels in rat adrenals by a single and repeated immobilization stress. J Neurochem. 1992 Jun; 58(6):2124-30.
McMahon A, Kvetnanský R, Fukuhara K, Weise VK, Kopin IJ, Sabban EL. PMID: 1349344.
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PubMed Mentions:
21 Fields:
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Animals
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The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell. 1992 May 15; 69(4):581-95.
McMahon AP, Joyner AL, Bradley A, McMahon JA. PMID: 1534034.
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PubMed Mentions:
128 Fields:
Translation:
AnimalsCells
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Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland. Mol Cell Biol. 1992 May; 12(5):2418-23.
Gavin BJ, McMahon AP. PMID: 1373817; PMCID: PMC364414.
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PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
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Regulated expression of the tyrosine hydroxylase gene by membrane depolarization. Identification of the responsive element and possible second messengers. J Biol Chem. 1992 Apr 15; 267(11):7563-9.
Kilbourne EJ, Nankova BB, Lewis EJ, McMahon A, Osaka H, Sabban DB, Sabban EL. PMID: 1348505.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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The Wnt family of cell signalling molecules in postimplantation development of the mouse. Ciba Found Symp. 1992; 165:199-212; discussion 212-8.
McMahon AP, Gavin BJ, Parr B, Bradley A, McMahon JA. PMID: 1516469.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Membrane depolarization by isotonic or hypertonic KCl: differential effects on mRNA levels of tyrosine hydroxylase and dopamine beta-hydroxylase mRNA in PC12 cells. J Neurosci Methods. 1991 Dec; 40(2-3):193-202.
Kilbourne EJ, McMahon A, Sabban EL. PMID: 1686923.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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FGFR-4, a new member of the fibroblast growth factor receptor family, expressed in the definitive endoderm and skeletal muscle lineages of the mouse. Development. 1991 Oct; 113(2):641-51.
Stark KL, McMahon JA, McMahon AP. PMID: 1723680.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis. Development. 1991 Apr; 111(4):1045-55.
Christian JL, McMahon JA, McMahon AP, Moon RT. PMID: 1879349.
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PubMed Mentions:
74 Fields:
Translation:
Animals
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Isolation of cDNAs partially encoding four Xenopus Wnt-1/int-1-related proteins and characterization of their transient expression during embryonic development. Dev Biol. 1991 Feb; 143(2):230-4.
Christian JL, Gavin BJ, McMahon AP, Moon RT. PMID: 1991549.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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A new nomenclature for int-1 and related genes: the Wnt gene family. Cell. 1991 Jan 25; 64(2):231.
Nusse R, Brown A, Papkoff J, Scambler P, Shackleford G, McMahon A, Moon R, Varmus H. PMID: 1846319.
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PubMed Mentions:
124 Fields:
Translation:
HumansAnimalsCells
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Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 1990 Dec; 4(12B):2319-32.
Gavin BJ, McMahon JA, McMahon AP. PMID: 2279700.
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PubMed Mentions:
83 Fields:
Translation:
AnimalsCells
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The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell. 1990 Sep 21; 62(6):1073-85.
McMahon AP, Bradley A. PMID: 2205396.
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PubMed Mentions:
419 Fields:
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AnimalsCells
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Generation of diversity in nonerythroid spectrins. Multiple polypeptides are predicted by sequence analysis of cDNAs encompassing the coding region of human nonerythroid alpha-spectrin. J Biol Chem. 1990 Mar 15; 265(8):4427-33.
Moon RT, McMahon AP. PMID: 2307671.
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PubMed Mentions:
26 Fields:
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HumansAnimalsCells
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Rat dopamine beta-hydroxylase: molecular cloning and characterization of the cDNA and regulation of the mRNA by reserpine. J Neurosci Res. 1990 Mar; 25(3):395-404.
McMahon A, Geertman R, Sabban EL. PMID: 2325165.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Developmental expression of the putative transcription factor Egr-1 suggests that Egr-1 and c-fos are coregulated in some tissues. Development. 1990 Feb; 108(2):281-7.
McMahon AP, Champion JE, McMahon JA, Sukhatme VP. PMID: 2351070.
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PubMed Mentions:
32 Fields:
Translation:
Animals
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Effect of compounds which disrupt proton gradients on secretion of neurosecretory proteins from PC12 pheochromocytoma cells. Neuroscience. 1990; 38(2):561-70.
Sabban EL, Schwartz J, McMahon A. PMID: 2175857.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Nucleotide sequence, chromosomal localization and developmental expression of the mouse int-1-related gene. Development. 1989 Nov; 107(3):643-50.
McMahon JA, McMahon AP. PMID: 2693041.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Endoglycosidase H susceptibility of secreted and intracellular forms of dopamine beta-hydroxylase. Biochem Int. 1989 Oct; 19(4):769-75.
Sabban EL, McMahon A, Kuhn LJ. PMID: 2515859.
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AnimalsCells
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Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis. Cell. 1989 Sep 22; 58(6):1075-84.
McMahon AP, Moon RT. PMID: 2673541.
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PubMed Mentions:
142 Fields:
Translation:
AnimalsCells
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Expression pattern of the FGF-related proto-oncogene int-2 suggests multiple roles in fetal development. Development. 1989 Jan; 105(1):131-6.
Wilkinson DG, Bhatt S, McMahon AP. PMID: 2680421.
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PubMed Mentions:
50 Fields:
Translation:
Animals
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int-1--a proto-oncogene involved in cell signalling. Development. 1989; 107 Suppl:161-7.
McMahon AP, Moon RT. PMID: 2534596.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse. EMBO J. 1988 Mar; 7(3):691-5.
Wilkinson DG, Peters G, Dickson C, McMahon AP. PMID: 3293998; PMCID: PMC454374.
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PubMed Mentions:
64 Fields:
Translation:
AnimalsCells
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Effects of ionizing radiation and pretreatment with [D-Leu6,des-Gly10] luteinizing hormone-releasing hormone ethylamide on developing rat ovarian follicles. Cancer Res. 1987 Oct 01; 47(19):5005-8.
Jarrell J, YoungLai EV, McMahon A, Barr R, O'Connell G, Belbeck L. PMID: 3113726.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Structure and evolution of a non-erythroid spectrin, human alpha-fodrin. Biochem Soc Trans. 1987 Oct; 15(5):804-7.
McMahon AP, Moon RT. PMID: 3691949.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo. Cell. 1987 Jul 03; 50(1):79-88.
Wilkinson DG, Bailes JA, McMahon AP. PMID: 3594565.
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PubMed Mentions:
117 Fields:
Translation:
AnimalsCells
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Ovarian toxicity of cyclophosphamide alone and in combination with ovarian irradiation in the rat. Cancer Res. 1987 May 01; 47(9):2340-3.
Jarrell J, Lai EV, Barr R, McMahon A, Belbeck L, O'Connell G. PMID: 3105875.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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A molecular analysis of mouse development from 8 to 10 days post coitum detects changes only in embryonic globin expression. Development. 1987 Apr; 99(4):493-500.
Wilkinson DG, Bailes JA, Champion JE, McMahon AP. PMID: 2444404.
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PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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cDNA cloning, sequencing and chromosome mapping of a non-erythroid spectrin, human alpha-fodrin. Differentiation. 1987; 34(1):68-78.
McMahon AP, Giebelhaus DH, Champion JE, Bailes JA, Lacey S, Carritt B, Henchman SK, Moon RT. PMID: 3038643.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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An analysis of the effects of increasing doses of ionizing radiation to the exteriorized rat ovary on follicular development, atresia, and serum gonadotropin levels. Am J Obstet Gynecol. 1986 Feb; 154(2):306-9.
Jarrell J, YoungLai EV, Barr R, O'Connell G, Belbeck L, McMahon A. PMID: 3080889.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Introduction of cloned DNA into sea urchin egg cytoplasm: replication and persistence during embryogenesis. Dev Biol. 1985 Apr; 108(2):420-30.
McMahon AP, Flytzanis CN, Hough-Evans BR, Katula KS, Britten RJ, Davidson EH. PMID: 3000854.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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Persistence and integration of cloned DNA in postembryonic sea urchins. Dev Biol. 1985 Apr; 108(2):431-42.
Flytzanis CN, McMahon AP, Hough-Evans BR, Katula KS, Britten RJ, Davidson EH. PMID: 3000855.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Inducible expression of a cloned heat shock fusion gene in sea urchin embryos. Proc Natl Acad Sci U S A. 1984 Dec; 81(23):7490-4.
McMahon AP, Novak TJ, Britten RJ, Davidson EH. PMID: 6594699; PMCID: PMC392172.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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Oocyte specific regulation of PGK-1 isozyme activity in female germ cells of the mouse. Genet Res. 1983 Aug; 42(1):77-89.
McMahon A. PMID: 6628991.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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X-chromosome inactivation mosaicism in the three germ layers and the germ line of the mouse embryo. J Embryol Exp Morphol. 1983 Apr; 74:207-20.
McMahon A, Fosten M, Monk M. PMID: 6886595.
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PubMed Mentions:
26 Fields:
Translation:
Animals
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X-chromosome activity in female mouse embryos heterozygous for Pgk-1 and Searle's translocation, T(X; 16) 16H. Genet Res. 1983 Feb; 41(1):69-83.
McMahon A, Monk M. PMID: 6840549.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Random X-chromosome inactivation in female primordial germ cells in the mouse. J Embryol Exp Morphol. 1981 Aug; 64:251-8.
McMahon A, Fosten M, Monk M. PMID: 7310304.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells