Alexander Lerner, MD

Title(s)Assistant Professor of Clinical Radiology
SchoolKeck School of Medicine of Usc
AddressGNH 3550
Off Campus
Los Angeles CA 90089-9311
Phone+1 323 226 7425
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    Pasadena Magazine2013  - 2015Top Doctors
    Pasadena Magazine2017  - 2017Top Doctors
    American Journal of Neuroradiology2018  - 2018Distinguished Reviewer

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    Dr. Lerner graduated from State University of New York at Buffalo School of Medicine in 2002. He completed a transitional year internship at Wilson Memorial Medical Center in Johnson City, NY from 2002 – 2003, and then completed a diagnostic radiology residency at Albert Einstein College of Medicine, Jacobi Medical Center in Bronx, NY in 2007. Dr. Lerner came to the University of Southern California to complete his fellowship training in Neuroradiology from 2007-2008. He has been a member of the faculty of the department of Radiology since 2008. He earned his CAQ in Neuroradiology in 2010.

    Dr Lerner is currently an Assistant Professor of Clinical Radiology and Director of Clinical Functional MRI. He serves as the director for the 4th year medical student Neuroradiology clinical clerkship. Dr. Lerner has been an invited speaker and at multiple radiology societies at regional and national levels. He has also authored and co-authored multiple publications and book chapters. Dr. Lerner serves as a member of the editorial board of the American Journal of Neuroradiology and as a reviewer for multiple medical journals. He is an active member of Los Angeles Radiological Society, Western Neuroradiological Society, American Society of Functional Neuroradiology, American Society of Neuroradiology, and Radiology Society of North America.

    Dr. Lerner’s research interests include advanced MR imaging using Functional MRI, DTI, MR Perfusion and Permeability Imaging of the brain and spinal Cord
    He specializes in the diagnosis of disorders causing headaches, neurovascular compression disorders, CSF flow disorders, epilepsy, inflammatory and degenerative disorders of the CNS.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Functional MRI and Diffusion Tensor Imaging in Migraine: A Review of Migraine Functional and White Matter Microstructural Changes. J Cent Nerv Syst Dis. 2023; 15:11795735231205413. Chou BC, Lerner A, Barisano G, Phung D, Xu W, Pinto SN, Sheikh-Bahaei N. PMID: 37900908; PMCID: PMC10612465.
      View in: PubMed   Mentions:
    2. A cross-sectional study to test equivalence of low- versus intermediate-flip angle dynamic susceptibility contrast MRI measures of relative cerebral blood volume in patients with high-grade gliomas at 1.5 Tesla field strength. Front Oncol. 2023; 13:1156843. Shiroishi MS, Weinert D, Cen SY, Varghese B, Dondlinger T, Prah M, Mendoza J, Nazemi S, Ameli N, Amini N, Shohas S, Chen S, Bigjahan B, Zada G, Chen T, Neman-Ebrahim J, Chang EL, Chow FE, Fan Z, Yang W, Attenello FJ, Ye J, Kim PE, Patel VN, Lerner A, Acharya J, Hu LS, Quarles CC, Boxerman JL, Wu O, Schmainda KM. PMID: 37799462; PMCID: PMC10548232.
      View in: PubMed   Mentions:
    3. Structural MRI in Migraine: A Review of Migraine Vascular and Structural Changes in Brain Parenchyma. J Cent Nerv Syst Dis. 2023; 15:11795735231167868. Xu WJ, Barisano G, Phung D, Chou B, Pinto SN, Lerner A, Sheikh-Bahaei N. PMID: 37077432; PMCID: PMC10108417.
      View in: PubMed   Mentions:
    4. Re: "Correlation of Automated Computed Tomography Volumetric Analysis Metrics With Motility Disturbances in Thyroid Eye Disease". Ophthalmic Plast Reconstr Surg. 2023 Mar-Apr 01; 39(2):194. Li J, Li S, Park KE, Wen J, Lee J, Ayala FA, Lerner A, Gokoffski KK, Zhang-Nunes S, Patel V, Chang JR. PMID: 36867765.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. VWI-APP: Vessel wall imaging-dedicated automated processing pipeline for intracranial atherosclerotic plaque quantification. Med Phys. 2023 Mar; 50(3):1496-1506. Zhou H, Xiao J, Ganesh S, Lerner A, Ruan D, Fan Z. PMID: 36345580; PMCID: PMC10033308.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Utility of Neuroimaging in the Management of Chronic and Acute Headache. Otolaryngol Clin North Am. 2022 Jun; 55(3):559-577. Lerner A, Sheikh-Bahaei N, Go JL. PMID: 35490044.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. A Comparison of WebRTC and Conventional Videoconferencing for Synchronized Remote Medical Image Presentation. J Digit Imaging. 2022 02; 35(1):68-76. Patel V, Li CH, Rye V, Liu CJ, Lerner A, Acharya J, Rajamohan AG. PMID: 34935095; PMCID: PMC8691158.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Utility of Contrast-Enhanced Ultrasound and 4-Dimensional Computed Tomography for Preoperative Detection and Localization of Parathyroid Adenomas Compared With Surgical Results. J Ultrasound Med. 2022 Sep; 41(9):2295-2306. Lerner A, Grant EG, Acharya J, Chambers TN, Maceri DR, Cen SY, Tchelepi H. PMID: 34918364.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Cerebrovascular disease in pregnancy and puerperium: perspectives from neuroradiologists. Quant Imaging Med Surg. 2021 Feb; 11(2):838-851. Wang N, Shen X, Zhang G, Gao B, Lerner A. PMID: 33532282; PMCID: PMC7779914.
      View in: PubMed   Mentions: 3  
    10. Changes in Social Media Impact of the Radiological Literature During the Covid-19 Pandemic. Acad Radiol. 2021 02; 28(2):151-157. Patel V, Li CH, Acharya J, Lerner A, Rajamohan AG. PMID: 33243677.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    11. Editorial: Posterior Reversible Encephalopathy Syndrome and Associated Diseases. Front Neurol. 2020; 11:667. Legriel S, Lerner A, Wintermark M, Rykken JB, Gao B. PMID: 32849174; PMCID: PMC7396664.
      View in: PubMed   Mentions: 1  
    12. Posterior Reversible Encephalopathy Syndrome (PRES): Pathophysiology and Neuro-Imaging. Front Neurol. 2020; 11:463. Anderson RC, Patel V, Sheikh-Bahaei N, Liu CSJ, Rajamohan AG, Shiroishi MS, Kim PE, Go JL, Lerner A, Acharya J. PMID: 32612567; PMCID: PMC7308488.
      View in: PubMed   Mentions: 27  
    13. Blood-Brain Barrier Disruption as a Potential Target for Therapy in Posterior Reversible Encephalopathy Syndrome: Evidence From Multimodal MRI in Rats. Front Neurol. 2019; 10:1211. Wang Q, Huang B, Shen G, Zeng Y, Chen Z, Lu C, Lerner A, Gao B. PMID: 31849806; PMCID: PMC6901929.
      View in: PubMed   Mentions: 3  
    14. Application of FLAIR Vascular Hyperintensity-DWI Mismatch in Ischemic Stroke Depending on Semi-Quantitative DWI-Alberta Stroke Program Early CT Score. Front Neurol. 2019; 10:994. Song L, Lyu C, Shen G, Guo T, Wang J, Wang W, Qiu X, Lerner A, Wintermark M, Gao B. PMID: 31611838; PMCID: PMC6776088.
      View in: PubMed   Mentions: 3  
    15. Signal Hyperintensity on Unenhanced T1-Weighted Brain and Cervical Spinal Cord MR Images after Multiple Doses of Linear Gadolinium-Based Contrast Agent. AJNR Am J Neuroradiol. 2019 08; 40(8):1274-1281. Barisano G, Bigjahan B, Metting S, Cen S, Amezcua L, Lerner A, Toga AW, Law M. PMID: 31345942; PMCID: PMC7048477.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Headache and Brain Tumor. Neuroimaging Clin N Am. 2019 May; 29(2):291-300. Hadidchi S, Surento W, Lerner A, Liu CJ, Gibbs WN, Kim PE, Shiroishi MS. PMID: 30926118.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    17. Imaging of cerebrovascular complications of infection. Quant Imaging Med Surg. 2018 Nov; 8(10):1039-1051. Shen G, Shen X, Pu W, Zhang G, Lerner A, Gao B. PMID: 30598881; PMCID: PMC6288057.
      View in: PubMed   Mentions: 3  
    18. Risk factors for poor outcome in posterior reversible encephalopathy syndrome: systematic review and meta-analysis. Quant Imaging Med Surg. 2018 May; 8(4):421-432. Chen Z, Zhang G, Lerner A, Wang AH, Gao B, Liu J. PMID: 29928607; PMCID: PMC5989088.
      View in: PubMed   Mentions: 19  
    19. Nervous System Injury and Neuroimaging of Zika Virus Infection. Front Neurol. 2018; 9:227. Wu S, Zeng Y, Lerner A, Gao B, Law M. PMID: 29740383; PMCID: PMC5926540.
      View in: PubMed   Mentions: 7  
    20. Brain cortical structural differences between non-central nervous system cancer patients treated with and without chemotherapy compared to non-cancer controls: a cross-sectional pilot MRI study using clinically-indicated scans. Proc SPIE Int Soc Opt Eng. 2017 Oct; 10572. Shiroishi MS, Gupta V, Bigjahan B, Cen SY, Rashid F, Hwang DH, Lerner A, Boyko OB, Liu CJ, Law M, Thompson PM, Jahanshad N. PMID: 30034079; PMCID: PMC6049823.
      View in: PubMed   Mentions: 3  
    21. Controversy of posterior reversible encephalopathy syndrome: what have we learnt in the last 20 years? J Neurol Neurosurg Psychiatry. 2018 01; 89(1):14-20. Gao B, Lyu C, Lerner A, McKinney AM. PMID: 28794149.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    22. Computed navigated total knee arthroplasty compared to computed tomography scans. Knee. 2017 Jun; 24(3):622-626. Batash R, Rubin G, Lerner A, Shehade H, Rozen N, Rothem DE. PMID: 28400204.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    23. Immune system activation in the pathogenesis of posterior reversible encephalopathy syndrome. Brain Res Bull. 2017 May; 131:93-99. Chen Z, Shen GQ, Lerner A, Gao B. PMID: 28373149.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    24. The Clinical Outcome of Posterior Reversible Encephalopathy Syndrome. AJNR Am J Neuroradiol. 2016 09; 37(9):E55-6. Gao B, Lerner A, Law M. PMID: 27365328; PMCID: PMC7984686.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. Atypical central neurocytoma with metastatic craniospinal dissemination: a case report. Clin Imaging. 2016 Nov - Dec; 40(6):1108-1111. Nayyar M, Mayo MC, Shiroishi M, Commins D, Liu CY, Go JL, Kim PE, Zee CS, Law M, Lerner A. PMID: 27450443.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. The Effect of Depo Medroxyprogesterone Acetate (DMPA) on Cerebral Food Motivation Centers: A Pilot Study using Functional Magnetic Resonance Imaging. Contraception. 2016 10; 94(4):321-7. Basu T, Bao P, Lerner A, Anderson L, Page K, Stanczyk F, Mishell D, Segall-Gutierrez P. PMID: 27129935.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    27. Predicting Meningioma Consistency on Preoperative Neuroimaging Studies. Neurosurg Clin N Am. 2016 Apr; 27(2):145-54. Shiroishi MS, Cen SY, Tamrazi B, D'Amore F, Lerner A, King KS, Kim PE, Law M, Hwang DH, Boyko OB, Liu CS. PMID: 27012379; PMCID: PMC4936899.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    28. Design and development of an ethnically-diverse imaging informatics-based eFolder system for multiple sclerosis patients. Comput Med Imaging Graph. 2015 Dec; 46 Pt 2:257-68. Ma KC, Fernandez JR, Amezcua L, Lerner A, Shiroishi MS, Liu BJ. PMID: 26564667; PMCID: PMC4936902.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Imaging of the Posttherapeutic Brain. Top Magn Reson Imaging. 2015 Jun; 24(3):147-54. Telles BA, D'Amore F, Lerner A, Law M, Shiroishi MS. PMID: 26049818.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    30. Ectopic ACTH-secreting pituitary adenoma of the sphenoid sinus: case report of endoscopic endonasal resection and systematic review of the literature. Neurosurg Focus. 2015 Feb; 38(2):E10. Seltzer J, Lucas J, Commins D, Lerner O, Lerner A, Carmichael JD, Zada G. PMID: 25639312.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    31. Concurrent intracranial and spinal subdural hematoma in a teenage athlete: a case report of this rare entity. Case Rep Radiol. 2014; 2014:143408. Treister DS, Kingston SE, Zada G, Singh M, Jones JG, Mills JN, Lerner A, Boyko OB, Law M, Rajamohan A, Shiroishi MS. PMID: 25349764; PMCID: PMC4198776.
      View in: PubMed   Mentions: 3  
    32. Image coregistration: quantitative processing framework for the assessment of brain lesions. J Digit Imaging. 2014 Jun; 27(3):369-79. Huhdanpaa H, Hwang DH, Gasparian GG, Booker MT, Cen Y, Lerner A, Boyko OB, Go JL, Kim PE, Rajamohan A, Law M, Shiroishi MS. PMID: 24395597; PMCID: PMC4026464.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    33. Diffusion restriction in a non-enhancing metastatic brain tumor treated with bevacizumab - recurrent tumor or atypical necrosis? Clin Imaging. 2014 Sep-Oct; 38(5):724-6. Sivasundaram L, Hazany S, Wagle N, Zada G, Chen TC, Lerner A, Go JL, D'Amore F, Law M, Shiroishi MS. PMID: 24910165.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    34. Clinical applications of diffusion tensor imaging. World Neurosurg. 2014 Jul-Aug; 82(1-2):96-109. Lerner A, Mogensen MA, Kim PE, Shiroishi MS, Hwang DH, Law M. PMID: 23916498.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    35. Spinal cord lesions and disability in Hispanics with multiple sclerosis. J Neurol. 2013 Nov; 260(11):2770-6. Amezcua L, Lerner A, Ledezma K, Conti D, Law M, Weiner L, Langer-Gould A. PMID: 23912723; PMCID: PMC3816004.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    36. Posttreatment evaluation of central nervous system gliomas. Magn Reson Imaging Clin N Am. 2013 May; 21(2):241-68. Shiroishi MS, Booker MT, Agarwal M, Jain N, Naghi I, Lerner A, Law M. PMID: 23642552.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    37. Spine infections. Neuroimaging Clin N Am. 2012 Nov; 22(4):755-72. Go JL, Rothman S, Prosper A, Silbergleit R, Lerner A. PMID: 23122265.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    38. Imaging of neurocysticercosis. Neuroimaging Clin N Am. 2012 Nov; 22(4):659-76. Lerner A, Shiroishi MS, Zee CS, Law M, Go JL. PMID: 23122261.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    39. A massive renal epithelioid angiomyolipoma with multiple metastatic lymph nodes. Clin Imaging. 2011 Jul-Aug; 35(4):320-3. Cui L, Hu XY, Gong SC, Fang XM, Lerner A, Zhou ZY. PMID: 21724128.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    40. Diffusion tensor imaging in the assessment of ossification of the posterior longitudinal ligament: a report on preliminary results in 3 cases and review of the literature. Neurosurg Focus. 2011 Mar; 30(3):E14. Jones J, Lerner A, Kim PE, Law M, Hsieh PC. PMID: 21361752.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    41. Perfusion and permeability MR imaging of gliomas. Technol Cancer Res Treat. 2011 Feb; 10(1):59-71. Shiroishi MS, Habibi M, Rajderkar D, Yurko C, Go JL, Lerner A, Mogensen MA, Kim PE, Boyko OB, Zee CS, Law M. PMID: 21214289.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    42. External fixation for temporary stabilization and wound management of an open pelvic ring injury with extensive soft tissue damage: case report and review of the literature. J Trauma. 2008 Sep; 65(3):715-8. Lerner A, Fodor L, Keren Y, Horesh Z, Soudry M. PMID: 17514047.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    43. Vascular compression in trigeminal neuralgia shown by magnetic resonance imaging and magnetic resonance angiography image registration. Arch Neurol. 2001 Aug; 58(8):1290-1. Bakshi R, Lerner A, Fritz JV, Sambuchi GD. PMID: 11493171.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
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