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    Tishya A.l. Wren, PhD

    TitleAssociate Professor of Research Orthopaedic Surgery and Radiology
    SchoolKeck School of Medicine of USC
    DepartmentPediatric Orthopaedic
    AddressCHL 4650 Sunset Blvd
    Off Campus
    Los Angeles California 90027
    Phone+1 323 361 4120
    Emailtwren@chla.usc.edu
    vCardDownload vCard

      Collapse Overview 
      Collapse Overview
      Dr. Wren is a biomedical engineer working in clinical environment. As Director of Research for the Children's Orthopaedic Center at Children's Hospital Los Angeles, Dr. Wren conducts clinical and basic research in several different areas of orthopaedics. Two of the primary areas are (1) evaluation and treatment of movement abnormalities in children with neurologic deficits and (2) assessment of bone and fractures in children. This research is carried out in collaboration with colleagues in the John C. Wilson, Jr. Motion Analysis Laboratory and the Children's Imaging Research Program.


      Collapse Biography 
      Collapse Awards and Honors
      American Academy of Orthopaedic Surgeons2015Best Paper Award - Pediatrics
      Gait and Clinical Movement Analysis Society2014Best Paper Award
      Pediatric Orthopaedic Society of North America2004Marc A. Asher Clinical Scientific Paper Award
      1992National Science Foundation Graduate Fellowship
      Amherst College1992Woods-Travis Valedictorian Award

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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Sousa TC, Nazareth A, Rethlefsen SA, Mueske NM, Wren T, Kay RM. Rectus Femoris Transfer Surgery Worsens Crouch Gait in Children With Cerebral Palsy at GMFCS Levels III and IV. J Pediatr Orthop. 2017 Apr 03. PMID: 28375967.
        View in: PubMed
      2. Wren T, Aggabao PC, Poorghasamians E, Chavez TA, Ponrartana S, Gilsanz V. Association between vertebral cross-sectional area and lumbar lordosis angle in adolescents. PLoS One. 2017; 12(2):e0172844. PMID: 28245271.
        View in: PubMed
      3. Orgel E, Mueske NM, Sposto R, Gilsanz V, Wren T, Freyer DR, Butturini AM, Mittelman SD. A randomized controlled trial testing an adherence-optimized Vitamin D regimen to mitigate bone change in adolescents being treated for acute lymphoblastic leukemia. Leuk Lymphoma. 2017 Feb 20; 1-9. PMID: 28278717.
        View in: PubMed
      4. Nazareth A, Rethlefsen S, Sousa TC, Mueske NM, Wren T, Kay RM. Percutaneous Hamstring Lengthening Surgery is as Effective as Open Lengthening in Children With Cerebral Palsy. J Pediatr Orthop. 2016 Dec 22. PMID: 28009799.
        View in: PubMed
      5. Gordon CM, Zemel BS, Wren T, Leonard MB, Bachrach LK, Rauch F, Gilsanz V, Rosen CJ, Winer KK. The Determinants of Peak Bone Mass. J Pediatr. 2016 Nov 3. PMID: 27816219.
        View in: PubMed
      6. Choi H, Wren T, Steele KM. Gastrocnemius operating length with ankle foot orthoses in cerebral palsy. Prosthet Orthot Int. 2016 Sep 09. PMID: 27613590.
        View in: PubMed
      7. Nazareth A, Mueske NM, Wren T. Effect of Tibia Marker Placement on Kinematics in Pathological Gait. J Appl Biomech. 2016 Sep 6; 1-15. PMID: 27619915.
        View in: PubMed
      8. Rethlefsen SA, Blumstein G, Kay RM, Dorey F, Wren T. Prevalence of specific gait abnormalities in children with cerebral palsy revisited: influence of age, prior surgery, and Gross Motor Function Classification System level. Dev Med Child Neurol. 2016 Jul 15. PMID: 27421715.
        View in: PubMed
      9. Yasmeh P, Mueske NM, Yasmeh S, Ryan DD, Wren T. Walking activity during daily living in children with myelomeningocele. Disabil Rehabil. 2016 Jul 6; 1-6. PMID: 27384911.
        View in: PubMed
      10. Ponrartana S, Fisher CL, Aggabao PC, Chavez TA, Broom AM, Wren T, Skaggs DL, Gilsanz V. Small vertebral cross-sectional area and tall intervertebral disc in adolescent idiopathic scoliosis. Pediatr Radiol. 2016 Sep; 46(10):1424-9. PMID: 27183842.
        View in: PubMed
      11. Lorenzana DJ, Mueske NM, Ryan DD, Van Speybroeck AL, Wren T. Quantitative Analysis of Lower Leg Adipose Tissue Distribution in Youth with Myelomeningocele. J Child Neurol. 2016 Jul; 31(8):979-84. PMID: 26961265.
        View in: PubMed
      12. Orgel E, Mueske NM, Wren T, Gilsanz V, Butturini AM, Freyer DR, Mittelman SD. Early injury to cortical and cancellous bone from induction chemotherapy for adolescents and young adults treated for acute lymphoblastic leukemia. Bone. 2016 Apr; 85:131-7. PMID: 26851412.
        View in: PubMed
      13. Zaslow TL, Pace JL, Mueske NM, Chua MC, Katzel MJ, Dennis SW, Wren T. Comparison of lateral shuffle and side-step cutting in young recreational athletes. Gait Posture. 2016 Feb; 44:189-93. PMID: 27004656.
        View in: PubMed
      14. Van Speybroeck A, Mueske NM, Mittelman SD, Kremer RK, Ryan DD, Wren T. Fasting serum blood measures of bone and lipid metabolism in children with myelomeningocele for early detection of cardiovascular and bone fragility risk factors. J Spinal Cord Med. 2015 Dec 14; 1-8. PMID: 26666357.
        View in: PubMed
      15. Rethlefsen SA, Nguyen DT, Wren T, Milewski MD, Kay RM. Knee Pain and Patellofemoral Symptoms in Patients With Cerebral Palsy. J Pediatr Orthop. 2015 Jul-Aug; 35(5):519-22. PMID: 25171680.
        View in: PubMed
      16. Ryan DD, Lightdale-Miric NR, Joiner ER, Wren T, Spragg L, Heffernan MJ, Kay RM, Skaggs DL. Variability of the Anterior Humeral Line in Normal Pediatric Elbows. J Pediatr Orthop. 2015 May 16. PMID: 26035494.
        View in: PubMed
      17. Wren T. Assessing bone accrual in cerebral palsy: new longitudinal data and future needs. Dev Med Child Neurol. 2015 May 6. PMID: 25951373.
        View in: PubMed
      18. Horenstein RE, Shefelbine SJ, Mueske NM, Fisher CL, Wren T. An approach for determining quantitative measures for bone volume and bone mass in the pediatric spina bifida population. Clin Biomech (Bristol, Avon). 2015 Apr 23. PMID: 26002057.
        View in: PubMed
      19. Wren T, Dryden JW, Mueske NM, Dennis SW, Healy BS, Rethlefsen SA. Comparison of 2 Orthotic Approaches in Children With Cerebral Palsy. Pediatr Phys Ther. 2015; 27(3):218-26. PMID: 26035652.
        View in: PubMed
      20. Lightdale-Miric N, Mueske NM, Lawrence EL, Loiselle J, Berggren J, Dayanidhi S, Stevanovic M, Valero-Cuevas FJ, Wren T. Long term functional outcomes after early childhood pollicization. J Hand Ther. 2015 Apr-Jun; 28(2):158-66. PMID: 25835252.
        View in: PubMed
      21. Stebbins J, Trinler UK, Baker R, Brunner R, Wren T, Theologis T. Recommendations for reporting gait studies. Gait Posture. 2015 Feb; 41(2):339-40. PMID: 25497141.
        View in: PubMed
      22. Ponrartana S, Ramos-Platt L, Wren T, Hu HH, Perkins TG, Chia JM, Gilsanz V. Effectiveness of diffusion tensor imaging in assessing disease severity in Duchenne muscular dystrophy: preliminary study. Pediatr Radiol. 2015 Apr; 45(4):582-9. PMID: 25246097.
        View in: PubMed
      23. Mueske NM, Ryan DD, Van Speybroeck AL, Chan LS, Wren T. Fat distribution in children and adolescents with myelomeningocele. Dev Med Child Neurol. 2015 Mar; 57(3):273-8. PMID: 25251828.
        View in: PubMed
      24. Lightdale-Miric N, Mueske NM, Dayanidhi S, Loiselle J, Berggren J, Lawrence EL, Stevanovic M, Valero-Cuevas FJ, Wren T. Quantitative assessment of dynamic control of fingertip forces after pollicization. Gait Posture. 2015 Jan; 41(1):1-6. PMID: 25262333.
        View in: PubMed
      25. Yu S, Rethlefsen SA, Wren T, Kay RM. Long-term Ambulatory Change After Lower Extremity Orthopaedic Surgery in Children With Cerebral Palsy: A Retrospective Review. J Pediatr Orthop. 2014 Jun 24. PMID: 24978124.
        View in: PubMed
      26. Ponrartana S, Andrade KE, Wren T, Ramos-Platt L, Hu HH, Bluml S, Gilsanz V. Repeatability of chemical-shift-encoded water-fat MRI and diffusion-tensor imaging in lower extremity muscles in children. AJR Am J Roentgenol. 2014 Jun; 202(6):W567-73. PMID: 24848851.
        View in: PubMed
      27. Ramirez RN, Ryan DD, Williams J, Wren T, Ibrahim D, Weiss JM, Kay RM, Lightdale-Miric N, Skaggs DL. A Line Drawn Along the Radial Shaft Misses the Capitellum in 16% of Radiographs of Normal Elbows. J Pediatr Orthop. 2014 Apr 29. PMID: 24787305.
        View in: PubMed
      28. Franklin CC, Wren T, Ferkel E, Arkader A. Predictors of conversion from conservative to operative treatment of pediatric forearm fractures. J Pediatr Orthop B. 2014 Mar; 23(2):150-4. PMID: 24322534.
        View in: PubMed
      29. Milewski MD, Skaggs DL, Bishop GA, Pace JL, Ibrahim DA, Wren T, Barzdukas A. Chronic Lack of Sleep is Associated With Increased Sports Injuries in Adolescent Athletes. J Pediatr Orthop. 2014 Mar; 34(2):129-33. PMID: 25028798.
        View in: PubMed
      30. Wren T, Kalkwarf HJ, Zemel BS, Lappe JM, Oberfield S, Shepherd JA, Winer KK, Gilsanz V. Longitudinal Tracking of Dual-Energy X-ray Absorptiometry Bone Measures Over 6 Years in Children and Adolescents: Persistence of Low Bone Mass to Maturity. J Pediatr. 2014 Jun; 164(6):1280-1285.e2. PMID: 24485819.
        View in: PubMed
      31. Wren T, Ponrartana S, Van Speybroeck A, Ryan DD, Chia JM, Hu HH. Heterogeneity of muscle fat infiltration in children with spina bifida. Res Dev Disabil. 2014 Jan; 35(1):215-22. PMID: 24169376.
        View in: PubMed
      32. Rethlefsen SA, Yasmeh S, Wren T, Kay RM. Repeat hamstring lengthening for crouch gait in children with cerebral palsy. J Pediatr Orthop. 2013 Jul-Aug; 33(5):501-4. PMID: 23752146.
        View in: PubMed
      33. Wren T, Lening C, Rethlefsen SA, Kay RM. Impact of gait analysis on correction of excessive hip internal rotation in ambulatory children with cerebral palsy: a randomized controlled trial. Dev Med Child Neurol. 2013 Oct; 55(10):919-25. PMID: 23738949.
        View in: PubMed
      34. Mueske NM, Chan LS, Wren T. Reliability of Lateral Distal Femur Dual-Energy X-Ray Absorptiometry Measures. J Clin Densitom. 2013 Mar 26. PMID: 23541123.
        View in: PubMed
      35. Wren T, Otsuka NY, Bowen RE, Scaduto AA, Chan LS, Dennis SW, Rethlefsen SA, Healy BS, Hara R, Sheng M, Kay RM. Outcomes of lower extremity orthopedic surgery in ambulatory children with cerebral palsy with and without gait analysis: results of a randomized controlled trial. Gait Posture. 2013 Jun; 38(2):236-41. PMID: 23219787.
        View in: PubMed
      36. Wren T, Shepherd JA, Kalkwarf HJ, Zemel BS, Lappe JM, Oberfield S, Dorey FJ, Winer KK, Gilsanz V. Racial disparity in fracture risk between white and nonwhite children in the United States. J Pediatr. 2012 Dec; 161(6):1035-40. PMID: 22974572.
        View in: PubMed
      37. Wren T, Elihu KJ, Mansour S, Rethlefsen SA, Ryan DD, Smith ML, Kay RM. Differences in implementation of gait analysis recommendations based on affiliation with a gait laboratory. Gait Posture. 2013 Feb; 37(2):206-9. PMID: 22871237.
        View in: PubMed
      38. Ponrartana S, Aggabao PC, Hu HH, Aldrovandi GM, Wren T, Gilsanz V. Brown adipose tissue and its relationship to bone structure in pediatric patients. J Clin Endocrinol Metab. 2012 Aug; 97(8):2693-8. PMID: 22593587.
        View in: PubMed
      39. Huh K, Rethlefsen SA, Wren T, Kay RM. Surgical Management of Hip Subluxation and Dislocation in Children With Cerebral Palsy: Isolated VDRO or Combined Surgery? J Pediatr Orthop. 2011 Dec; 31(8):858-63. PMID: 22101664.
        View in: PubMed
      40. Gilsanz V, Smith ML, Goodarzian F, Kim M, Wren T, Hu HH. Changes in Brown Adipose Tissue in Boys and Girls during Childhood and Puberty. J Pediatr. 2012 Apr; 160(4):604-609.e1. PMID: 22048045.
        View in: PubMed
      41. Aisen ML, Kerkovich D, Mast J, Mulroy S, Wren T, Kay RM, Rethlefsen SA. Cerebral palsy: clinical care and neurological rehabilitation. Lancet Neurol. 2011 Sep; 10(9):844-52. PMID: 21849165.
        View in: PubMed
      42. Wren T, Otsuka NY, Bowen RE, Scaduto AA, Chan LS, Sheng M, Hara R, Kay RM. Influence of gait analysis on decision-making for lower extremity orthopaedic surgery: Baseline data from a randomized controlled trial. Gait Posture. 2011 Jul; 34(3):364-9. PMID: 21723131.
        View in: PubMed
      43. Wren T, Gorton GE, Ounpuu S, Tucker CA. Efficacy of clinical gait analysis: A systematic review. Gait Posture. 2011 Jun; 34(2):149-53. PMID: 21646022.
        View in: PubMed
      44. Wren T, Chung SA, Dorey FJ, Bluml S, Adams GB, Gilsanz V. Bone marrow fat is inversely related to cortical bone in young and old subjects. J Clin Endocrinol Metab. 2011 Mar; 96(3):782-6. PMID: 21177790.
        View in: PubMed
      45. Al Wren T, Lee DC, Kay RM, Dorey FJ, Gilsanz V. Bone density and size in ambulatory children with cerebral palsy. Dev Med Child Neurol. 2011 Feb; 53(2):137-41. PMID: 21166671.
        View in: PubMed
      46. Wren T, Lee DC, Hara R, Rethlefsen SA, Kay RM, Dorey FJ, Gilsanz V. Effect of high-frequency, low-magnitude vibration on bone and muscle in children with cerebral palsy. J Pediatr Orthop. 2010 Oct-Nov; 30(7):732-8. PMID: 20864862.
        View in: PubMed
      47. Rethlefsen SA, Lening C, Wren T, Kay RM. Excessive hip flexion during gait in patients with static encephalopathy: an examination of contributing factors. J Pediatr Orthop. 2010 Sep; 30(6):562-7. PMID: 20733421.
        View in: PubMed
      48. Gilsanz V, Chalfant J, Kalkwarf H, Zemel B, Lappe J, Oberfield S, Shepherd J, Wren T, Winer K. Age at onset of puberty predicts bone mass in young adulthood. J Pediatr. 2011 Jan; 158(1):100-5, 105.e1-2. PMID: 20797727.
        View in: PubMed
      49. Wren T, Cheatwood AP, Rethlefsen SA, Hara R, Perez FJ, Kay RM. Achilles tendon length and medial gastrocnemius architecture in children with cerebral palsy and equinus gait. J Pediatr Orthop. 2010 Jul-Aug; 30(5):479-84. PMID: 20574267.
        View in: PubMed
      50. Di Iorgi N, Mo AO, Grimm K, Wren T, Dorey F, Gilsanz V. Bone acquisition in healthy young females is reciprocally related to marrow adiposity. J Clin Endocrinol Metab. 2010 Jun; 95(6):2977-82. PMID: 20392872.
        View in: PubMed
      51. Huh K, Rethlefsen SA, Wren T, Kay RM. Development of calcaneal gait without prior triceps surae lengthening: an examination of predictive factors. J Pediatr Orthop. 2010 Apr-May; 30(3):240-3. PMID: 20357589.
        View in: PubMed
      52. Bernthal NM, Gamradt SC, Kay RM, Wren T, Cuomo AV, Reid J, Bales J, Otsuka NY. Static and dynamic gait parameters before and after multilevel soft tissue surgery in ambulating children with cerebral palsy. J Pediatr Orthop. 2010 Mar; 30(2):174-9. PMID: 20179566.
        View in: PubMed
      53. Gilsanz V, Kremer A, Mo AO, Wren T, Kremer R. Vitamin D status and its relation to muscle mass and muscle fat in young women. J Clin Endocrinol Metab. 2010 Apr; 95(4):1595-601. PMID: 20164290.
        View in: PubMed
      54. Wren T, Gilsanz V. Evolving role of imaging in the evaluation of bone structure. J Bone Miner Res. 2009 Dec; 24(12):1943-5. PMID: 19839775.
        View in: PubMed
      55. Skaggs DL, Sankar WN, Albrektson J, Wren T, Campbell RM. Weight gain following vertical expandable prosthetic titanium ribs surgery in children with thoracic insufficiency syndrome. Spine (Phila Pa 1976). 2009 Nov 1; 34(23):2530-3. PMID: 19927103.
        View in: PubMed
      56. Wren T, Kalisvaart MM, Ghatan CE, Rethlefsen SA, Hara R, Sheng M, Chan LS, Kay RM. Effects of preoperative gait analysis on costs and amount of surgery. J Pediatr Orthop. 2009 Sep; 29(6):558-63. PMID: 19700983.
        View in: PubMed
      57. Lee DC, Campbell PP, Gilsanz V, Wren T. Contribution of the vertebral posterior elements in anterior-posterior DXA spine scans in young subjects. J Bone Miner Res. 2009 Aug; 24(8):1398-403. PMID: 19257831.
        View in: PubMed
      58. Wren T, Engsberg JR. Normalizing lower extremity strength data for children, adolescents, and young adults with cerebral palsy. J Appl Biomech. 2009 Aug; 25(3):195-202. PMID: 19827468.
        View in: PubMed
      59. Rethlefsen SA, Kam G, Wren T, Kay RM. Predictors of outcome of distal rectus femoris transfer surgery in ambulatory children with cerebral palsy. J Pediatr Orthop B. 2009 Mar; 18(2):58-62. PMID: 19282786.
        View in: PubMed
      60. Wren T, Chen AY, Wang VJ, Claudius IA, Skaggs DL. Prior treatment of fracture patients in a tertiary pediatric emergency department: informal referrals from other emergency departments. J Pediatr Orthop. 2009 Mar; 29(2):137-41. PMID: 19352238.
        View in: PubMed
      61. Engsberg JR, Tucker C, Ounpuu S, Wren T, Sisto SA, Kaufman KR. Gait and clinical movement analysis research priorities: 2007 update from the research committee of the Gait and Clinical Movement Analysis Society. Gait Posture. 2009 Feb; 29(2):169-71. PMID: 19135373.
        View in: PubMed
      62. Yu GY, Yan CH, Yu XG, Zuo Y, Zou XY, Xu J, Wu SH, Shen XM. [Effects of chelation therapy with succimer in young rabbits of moderate lead poisoning]. Zhonghua Yu Fang Yi Xue Za Zhi. 2009 Jan; 43(1):8-13. PMID: 19534872.
        View in: PubMed
      63. Gilsanz V, Perez FJ, Campbell PP, Dorey FJ, Lee DC, Wren T. Quantitative CT reference values for vertebral trabecular bone density in children and young adults. Radiology. 2009 Jan; 250(1):222-7. PMID: 19001149.
        View in: PubMed
      64. Gonzalez J, Wood JC, Dorey FJ, Wren T, Gilsanz V. Reproducibility of carotid intima-media thickness measurements in young adults. Radiology. 2008 May; 247(2):465-71. PMID: 18349312.
        View in: PubMed
      65. Wren T, Sheng M, Bowen RE, Scaduto AA, Kay RM, Otsuka NY, Hara R, Chan LS. Concurrent and discriminant validity of Spanish language instruments for measuring functional health status. J Pediatr Orthop. 2008 Mar; 28(2):199-212. PMID: 18388716.
        View in: PubMed
      66. Wren T, Bluml S, Tseng-Ong L, Gilsanz V. Three-point technique of fat quantification of muscle tissue as a marker of disease progression in Duchenne muscular dystrophy: preliminary study. AJR Am J Roentgenol. 2008 Jan; 190(1):W8-12. PMID: 18094282.
        View in: PubMed
      67. Wren T, Engsberg JR. Normalizing lower-extremity strength data for children without disability using allometric scaling. Arch Phys Med Rehabil. 2007 Nov; 88(11):1446-51. PMID: 17964886.
        View in: PubMed
      68. Wren T, Do KP, Hara R, Dorey FJ, Kay RM, Otsuka NY. Gillette Gait Index as a gait analysis summary measure: comparison with qualitative visual assessments of overall gait. J Pediatr Orthop. 2007 Oct-Nov; 27(7):765-8. PMID: 17878782.
        View in: PubMed
      69. Wren T, Do KP, Hara R, Rethlefsen SA. Use of a patella marker to improve tracking of dynamic hip rotation range of motion. Gait Posture. 2008 Apr; 27(3):530-4. PMID: 17703941.
        View in: PubMed
      70. Lee DC, Gilsanz V, Wren T. Limitations of peripheral quantitative computed tomography metaphyseal bone density measurements. J Clin Endocrinol Metab. 2007 Nov; 92(11):4248-53. PMID: 17684050.
        View in: PubMed
      71. Wren T, Mitiguy PC. A simple method to obtain consistent and clinically meaningful pelvic angles from euler angles during gait analysis. J Appl Biomech. 2007 Aug; 23(3):218-23. PMID: 18089919.
        View in: PubMed
      72. Wren T, Sheng M, Hara R, Otsuka NY, Bowen RE, Scaduto AA, Kay RM, Chan LS. Agreement among three instruments for measuring functional health status and quality of life in pediatric orthopaedics. J Pediatr Orthop. 2007 Mar; 27(2):233-40. PMID: 17314653.
        View in: PubMed
      73. Gilsanz V, Wren T. Assessment of bone acquisition in childhood and adolescence. Pediatrics. 2007 Mar; 119 Suppl 2:S145-9. PMID: 17332235.
        View in: PubMed
      74. Wren T, Kim PS, Janicka A, Sanchez M, Gilsanz V. Timing of peak bone mass: discrepancies between CT and DXA. J Clin Endocrinol Metab. 2007 Mar; 92(3):938-41. PMID: 17164299.
        View in: PubMed
      75. Wren T, Gilsanz V. Assessing bone mass in children and adolescents. Curr Osteoporos Rep. 2006 Dec; 4(4):153-8. PMID: 17112426.
        View in: PubMed
      76. Janicka A, Wren T, Sanchez MM, Dorey F, Kim PS, Mittelman SD, Gilsanz V. Fat mass is not beneficial to bone in adolescents and young adults. J Clin Endocrinol Metab. 2007 Jan; 92(1):143-7. PMID: 17047019.
        View in: PubMed
      77. Rethlefsen SA, Healy BS, Wren T, Skaggs DL, Kay RM. Causes of intoeing gait in children with cerebral palsy. J Bone Joint Surg Am. 2006 Oct; 88(10):2175-80. PMID: 17015594.
        View in: PubMed
      78. Gilsanz V, Wren T, Sanchez M, Dorey F, Judex S, Rubin C. Low-level, high-frequency mechanical signals enhance musculoskeletal development of young women with low BMD. J Bone Miner Res. 2006 Sep; 21(9):1464-74. PMID: 16939405.
        View in: PubMed
      79. Wren T, Do KP, Rethlefsen SA, Healy B. Cross-correlation as a method for comparing dynamic electromyography signals during gait. J Biomech. 2006; 39(14):2714-8. PMID: 16219314.
        View in: PubMed
      80. Wren T, Rethlefsen SA, Healy BS, Do KP, Dennis SW, Kay RM. Reliability and validity of visual assessments of gait using a modified physician rating scale for crouch and foot contact. J Pediatr Orthop. 2005 Sep-Oct; 25(5):646-50. PMID: 16199948.
        View in: PubMed
      81. Wren T, Liu X, Pitukcheewanont P, Gilsanz V. Bone densitometry in pediatric populations: discrepancies in the diagnosis of osteoporosis by DXA and CT. J Pediatr. 2005 Jun; 146(6):776-9. PMID: 15973317.
        View in: PubMed
      82. Wren T, Woolf K, Kay RM. How closely do surgeons follow gait analysis recommendations and why? J Pediatr Orthop B. 2005 May; 14(3):202-5. PMID: 15812293.
        View in: PubMed
      83. Wren T, Liu X, Pitukcheewanont P, Gilsanz V. Bone acquisition in healthy children and adolescents: comparisons of dual-energy x-ray absorptiometry and computed tomography measures. J Clin Endocrinol Metab. 2005 Apr; 90(4):1925-8. PMID: 15634720.
        View in: PubMed
      84. Wren T, Rethlefsen S, Kay RM. Prevalence of specific gait abnormalities in children with cerebral palsy: influence of cerebral palsy subtype, age, and previous surgery. J Pediatr Orthop. 2005 Jan-Feb; 25(1):79-83. PMID: 15614065.
        View in: PubMed
      85. Kay RM, Rethlefsen SA, Fern-Buneo A, Wren T, Skaggs DL. Botulinum toxin as an adjunct to serial casting treatment in children with cerebral palsy. J Bone Joint Surg Am. 2004 Nov; 86-A(11):2377-84. PMID: 15523006.
        View in: PubMed
      86. Wren T, Do KP, Kay RM. Gastrocnemius and soleus lengths in cerebral palsy equinus gait--differences between children with and without static contracture and effects of gastrocnemius recession. J Biomech. 2004 Sep; 37(9):1321-7. PMID: 15275839.
        View in: PubMed
      87. Kay RM, Rethlefsen S, Reed M, Do KP, Skaggs DL, Wren T. Changes in pelvic rotation after soft tissue and bony surgery in ambulatory children with cerebral palsy. J Pediatr Orthop. 2004 May-Jun; 24(3):278-82. PMID: 15105723.
        View in: PubMed
      88. Kay RM, Rethlefsen SA, Ryan JA, Wren T. Outcome of gastrocnemius recession and tendo-achilles lengthening in ambulatory children with cerebral palsy. J Pediatr Orthop B. 2004 Mar; 13(2):92-8. PMID: 15076586.
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      89. Kay RM, Rethlefsen SA, Kelly JP, Wren T. Predictive value of the Duncan-Ely test in distal rectus femoris transfer. J Pediatr Orthop. 2004 Jan-Feb; 24(1):59-62. PMID: 14676535.
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      90. Wren T. A computational model for the adaptation of muscle and tendon length to average muscle length and minimum tendon strain. J Biomech. 2003 Aug; 36(8):1117-24. PMID: 12831737.
        View in: PubMed
      91. Loboa EG, Wren T, Beaupré GS, Carter DR. Mechanobiology of soft skeletal tissue differentiation--a computational approach of a fiber-reinforced poroelastic model based on homogeneous and isotropic simplifications. Biomech Model Mechanobiol. 2003 Nov; 2(2):83-96. PMID: 14586808.
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      92. Wren T, Lindsey DP, Beaupré GS, Carter DR. Effects of creep and cyclic loading on the mechanical properties and failure of human Achilles tendons. Ann Biomed Eng. 2003 Jun; 31(6):710-7. PMID: 12797621.
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      93. Wren T, Yerby SA, Beaupré GS, Carter DR. Influence of bone mineral density, age, and strain rate on the failure mode of human Achilles tendons. Clin Biomech (Bristol, Avon). 2001 Jul; 16(6):529-34. PMID: 11427296.
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      94. Wren T, Yerby SA, Beaupré GS, Carter DR. Mechanical properties of the human achilles tendon. Clin Biomech (Bristol, Avon). 2001 Mar; 16(3):245-51. PMID: 11240060.
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      95. Wren T, Yerby SA, Beaupré GS, Carter DR. Interpretation of calcaneus dual-energy X-ray absorptiometry measurements in the assessment of osteopenia and fracture risk. J Bone Miner Res. 2000 Aug; 15(8):1573-8. PMID: 10934656.
        View in: PubMed
      96. Wren T, Beaupré GS, Carter DR. Mechanobiology of tendon adaptation to compressive loading through fibrocartilaginous metaplasia. J Rehabil Res Dev. 2000 Mar-Apr; 37(2):135-43. PMID: 10850819.
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      97. Wren T, Beaupré GS, Carter DR. Tendon and ligament adaptation to exercise, immobilization, and remobilization. J Rehabil Res Dev. 2000 Mar-Apr; 37(2):217-24. PMID: 10850828.
        View in: PubMed
      98. Wren T, Beaupré GS, Carter DR. A model for loading-dependent growth, development, and adaptation of tendons and ligaments. J Biomech. 1998 Feb; 31(2):107-14. PMID: 9593203.
        View in: PubMed
      99. Wren T, Carter DR. A microstructural model for the tensile constitutive and failure behavior of soft skeletal connective tissues. J Biomech Eng. 1998 Feb; 120(1):55-61. PMID: 9675681.
        View in: PubMed