Loading...
Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Stephen B Gruber, MD, PhD, MPH

    TitleProfessor of Medicine and Preventive Medicine
    SchoolKeck School of Medicine of USC
    DepartmentMedicine
    AddressNTT 4436
    Health Sciences Campus
    Los Angeles California 90089-9176
    Phone+1 323 865 0816
    vCardDownload vCard
      Other Positions
      TitleJane & Kris Popovich Chair in Cancer Research


      Collapse Overview 
      Collapse Overview
      Stephen B. Gruber, M.D., Ph.D., M.P.H., Director of the USC Norris Comprehensive Cancer Center, is a Professor of Medicine at the Keck School of Medicine of the University of Southern California, and the H. Leslie Hoffman and Elaine S. Hoffman Chair in Cancer Research.

      Dr. Gruber is a board certified medical oncologist, cancer geneticist and epidemiologist whose research focuses on genetic and environmental contributions to cancer. His particular research interests include the genetic epidemiology of cancer, with emphasis on colorectal cancer; the molecular pathogenesis of cancer, integrated with genetic epidemiology; methods in genetic and molecular epidemiology; and clinical cancer genetics and translational research in cancer prevention. The goal of his research is to find new ways to prevent cancer and to improve treatment and care for cancer patients.

      Dr. Gruber obtained his Bachelor’s Degree from the University of Pennsylvania in 1984 and subsequently a Master of Public Health Degree from Yale University in 1986. After completing his Doctorate Degree in Epidemiology at Yale in 1988, Dr. Gruber enrolled in the University of Pennsylvania Medical School and obtained his Medical Degree in 1992, where he also completed his internship and residency. He completed fellowships in medical oncology at Johns Hopkins Hospital and in clinical medical genetics at the University of Michigan.

      He has received a variety of honors and awards and is the author of 158 peer-reviewed publications, many in very high quality journals attesting to his standing in the field of cancer genetics, particularly as it relates to colorectal cancer. In addition to serving on editorial boards for several professional journals, Dr. Gruber is active in national organizations. Since 2005, he has been chair of the Colorectal Family Registries Advisory Panel for the National Cancer Institute and for the past three years chaired the Cancer Genetics Education Committee of the American Society of Clinical Oncology.


      Collapse Biography 
      Collapse Awards and Honors
      National Institute of Health1986  - 1988Cancer Training Grant
      1989  - 1992Penn Medical Scholar
      1992Alfred Stengel Memorial Prize
      1994Penn Pearls Teaching Award
      2000Jerome Conn Award for Excellence in Research
      American Society of Clinical Investigation2003Elected Member
      University of Michigan2011League of Research Excellence
      USC2012H. Leslie and Elaine S. Hoffman Cancer Research Chair
      Collaborative Group of the Americas on Inherited Colorectal Cancer 2013Lifetime Achievement Award
      Association of American Cancer Institute2015Board of Directors

      Collapse ORNG Applications 
      Collapse Websites
      Collapse Featured Videos
      Collapse In The News
      Collapse Twitter

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Thomas NE, Edmiston SN, Kanetsky PA, Busam KJ, Kricker A, Armstrong BK, Cust AE, Anton-Culver H, Gruber S, Luo L, Orlow I, Reiner AS, Gallagher RP, Zanetti R, Rosso S, Sacchetto L, Dwyer T, Parrish EA, Hao H, Gibbs DC, Frank JS, Ollila DW, Begg CB, Berwick M, Conway K. Associations of MC1R genotype and patient phenotypes with BRAF and NRAS mutations in melanoma. J Invest Dermatol. 2017 Aug 22. PMID: 28842324.
        View in: PubMed
      2. Baezconde-Garbanati L, Lienemann BA, Robles M, Johnson E, Sanchez K, Singhal R, Steinberg J, Jaque JM, Pentz MA, Gruber S. Implementation of HPV vaccination guidelines in a diverse population in Los Angeles: Results from an environmental scan of local HPV resources and needs. Vaccine. 2017 Sep 05; 35(37):4930-4935. PMID: 28774559.
        View in: PubMed
      3. Gu F, Zhang H, Hyland PL, Berndt S, Gapstur SM, Wheeler W, Ellipse Consortium T, Amos CI, Bezieau S, Bickeböller H, Brenner H, Brennan P, Chang-Claude J, Conti DV, Doherty JA, Gruber S, Harrison TA, Hayes RB, Hoffmeister M, Houlston RS, Hung RJ, Jenkins MA, Kraft P, Lawrenson K, McKay J, Markt S, Mucci L, Phelan CM, Qu C, Risch A, Rossing MA, Wichmann HE, Shi J, Schernhammer E, Yu K, Landi MT, Caporaso NE. Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia. Int J Cancer. 2017 Nov 01; 141(9):1794-1802. PMID: 28699174.
        View in: PubMed
      4. Vernali S, Waxweiler WT, Dillon PM, Kanetsky PA, Orlow I, Luo L, Busam KJ, Kricker A, Armstrong BK, Anton-Culver H, Gruber S, Gallagher RP, Zanetti R, Rosso S, Sacchetto L, Dwyer T, Cust AE, Ollila DW, Begg CB, Berwick M, Thomas NE. Association of Incident Amelanotic Melanoma With Phenotypic Characteristics, MC1R Status, and Prior Amelanotic Melanoma. JAMA Dermatol. 2017 Jul 26. PMID: 28746718.
        View in: PubMed
      5. Lindström S, Finucane H, Bulik-Sullivan B, Schumacher FR, Amos CI, Hung RJ, Rand K, Gruber S, Conti D, Permuth JB, Lin HY, Goode EL, Sellers TA, Amundadottir LT, Stolzenberg-Solomon R, Klein A, Petersen G, Risch H, Wolpin B, Hsu L, Huyghe JR, Chang-Claude J, Chan A, Berndt S, Eeles R, Easton D, Haiman CA, Hunter DJ, Neale B, Price AL, Kraft P. Quantifying the Genetic Correlation between Multiple Cancer Types. Cancer Epidemiol Biomarkers Prev. 2017 Sep; 26(9):1427-1435. PMID: 28637796.
        View in: PubMed
      6. Irabor DO, Oluwasola OA, Ogunbiyi OJ, Ogun OG, Okolo CA, Melas M, Gruber S, Shi C, Raskin L. Microsatellite Instability Is Common in Colorectal Cancer in Native Nigerians. Anticancer Res. 2017 05; 37(5):2649-2654. PMID: 28476840.
        View in: PubMed
      7. Phelan CM, Kuchenbaecker KB, Tyrer JP, Kar SP, Lawrenson K, Winham SJ, Dennis J, Pirie A, Riggan MJ, Chornokur G, Earp MA, Lyra PC, Lee JM, Coetzee S, Beesley J, McGuffog L, Soucy P, Dicks E, Lee A, Barrowdale D, Lecarpentier J, Leslie G, Aalfs CM, Aben KKH, Adams M, Adlard J, Andrulis IL, Anton-Culver H, Antonenkova N, Aravantinos G, Arnold N, Arun BK, Arver B, Azzollini J, Balmaña J, Banerjee SN, Barjhoux L, Barkardottir RB, Bean Y, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bermisheva M, Bernardini MQ, Birrer MJ, Bjorge L, Black A, Blankstein K, Blok MJ, Bodelon C, Bogdanova N, Bojesen A, Bonanni B, Borg Å, Bradbury AR, Brenton JD, Brewer C, Brinton L, Broberg P, Brooks-Wilson A, Bruinsma F, Brunet J, Buecher B, Butzow R, Buys SS, Caldes T, Caligo MA, Campbell I, Cannioto R, Carney ME, Cescon T, Chan SB, Chang-Claude J, Chanock S, Chen XQ, Chiew YE, Chiquette J, Chung WK, Claes KBM, Conner T, Cook LS, Cook J, Cramer DW, Cunningham JM, D'Aloisio AA, Daly MB, Damiola F, Damirovna SD, Dansonka-Mieszkowska A, Dao F, Davidson R, DeFazio A, Delnatte C, Doheny KF, Diez O, Ding YC, Doherty JA, Domchek SM, Dorfling CM, Dörk T, Dossus L, Duran M, Dürst M, Dworniczak B, Eccles D, Edwards T, Eeles R, Eilber U, Ejlertsen B, Ekici AB, Ellis S, Elvira M, Eng KH, Engel C, Evans DG, Fasching PA, Ferguson S, Ferrer SF, Flanagan JM, Fogarty ZC, Fortner RT, Fostira F, Foulkes WD, Fountzilas G, Fridley BL, Friebel TM, Friedman E, Frost D, Ganz PA, Garber J, García MJ, Garcia-Barberan V, Gehrig A, Gentry-Maharaj A, Gerdes AM, Giles GG, Glasspool R, Glendon G, Godwin AK, Goldgar DE, Goranova T, Gore M, Greene MH, Gronwald J, Gruber S, Hahnen E, Haiman CA, Håkansson N, Hamann U, Hansen TVO, Harrington PA, Harris HR, Hauke J, Hein A, Henderson A, Hildebrandt MAT, Hillemanns P, Hodgson S, Høgdall CK, Høgdall E, Hogervorst FBL, Holland H, Hooning MJ, Hosking K, Huang RY, Hulick PJ, Hung J, Hunter DJ, Huntsman DG, Huzarski T, Imyanitov EN, Isaacs C, Iversen ES, Izatt L, Izquierdo A, Jakubowska A, James P, Janavicius R, Jernetz M, Jensen A, Jensen UB, John EM, Johnatty S, Jones ME, Kannisto P, Karlan BY, Karnezis A, Kast K, Kennedy CJ, Khusnutdinova E, Kiemeney LA, Kiiski JI, Kim SW, Kjaer SK, Köbel M, Kopperud RK, Kruse TA, Kupryjanczyk J, Kwong A, Laitman Y, Lambrechts D, Larrañaga N, Larson MC, Lazaro C, Le ND, Le Marchand L, Lee JW, Lele SB, Leminen A, Leroux D, Lester J, Lesueur F, Levine DA, Liang D, Liebrich C, Lilyquist J, Lipworth L, Lissowska J, Lu KH, Lubinnski J, Luccarini C, Lundvall L, Mai PL, Mendoza-Fandiño G, Manoukian S, Massuger LFAG, May T, Mazoyer S, McAlpine JN, McGuire V, McLaughlin JR, McNeish I, Meijers-Heijboer H, Meindl A, Menon U, Mensenkamp AR, Merritt MA, Milne RL, Mitchell G, Modugno F, Moes-Sosnowska J, Moffitt M, Montagna M, Moysich KB, Mulligan AM, Musinsky J, Nathanson KL, Nedergaard L, Ness RB, Neuhausen SL, Nevanlinna H, Niederacher D, Nussbaum RL, Odunsi K, Olah E, Olopade OI, Olsson H, Olswold C, O'Malley DM, Ong KR, Onland-Moret NC, Orr N, Orsulic S, Osorio A, Palli D, Papi L, Park-Simon TW, Paul J, Pearce CL, Pedersen IS, Peeters PHM, Peissel B, Peixoto A, Pejovic T, Pelttari LM, Permuth JB, Peterlongo P, Pezzani L, Pfeiler G, Phillips KA, Piedmonte M, Pike MC, Piskorz AM, Poblete SR, Pocza T, Poole EM, Poppe B, Porteous ME, Prieur F, Prokofyeva D, Pugh E, Pujana MA, Pujol P, Radice P, Rantala J, Rappaport-Fuerhauser C, Rennert G, Rhiem K, Rice P, Richardson A, Robson M, Rodriguez GC, Rodríguez-Antona C, Romm J, Rookus MA, Rossing MA, Rothstein JH, Rudolph A, Runnebaum IB, Salvesen HB, Sandler DP, Schoemaker MJ, Senter L, Setiawan VW, Severi G, Sharma P, Shelford T, Siddiqui N, Side LE, Sieh W, Singer CF, Sobol H, Song H, Southey MC, Spurdle AB, Stadler Z, Steinemann D, Stoppa-Lyonnet D, Sucheston-Campbell LE, Sukiennicki G, Sutphen R, Sutter C, Swerdlow AJ, Szabo CI, Szafron L, Tan YY, Taylor JA, Tea MK, Teixeira MR, Teo SH, Terry KL, Thompson PJ, Thomsen LCV, Thull DL, Tihomirova L, Tinker AV, et al. Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Nat Genet. 2017 May; 49(5):680-691. PMID: 28346442.
        View in: PubMed
      8. Maoz A, Rennert G, Gruber S. T-Cell Transfer Therapy Targeting Mutant KRAS. N Engl J Med. 2017 02 16; 376(7):e11. PMID: 28207209.
        View in: PubMed
      9. Sunga AY, Ricker C, Espenschied CR, Castillo D, Melas M, Herzog J, Bannon S, Cruz-Correa M, Lynch P, Solomon I, Gruber S, Weitzel JN. Spectrum of mismatch repair gene mutations and clinical presentation of Hispanic individuals with Lynch syndrome. Cancer Genet. 2017 Apr; 212-213:1-7. PMID: 28449805.
        View in: PubMed
      10. White KA, Luo L, Thompson TA, Torres S, Hu CA, Thomas NE, Lilyquist J, Anton-Culver H, Gruber S, From L, Busam KJ, Orlow I, Kanetsky PA, Marrett LD, Gallagher RP, Sacchetto L, Rosso S, Dwyer T, Cust AE, Begg CB, Berwick M. Variants in autophagy-related genes and clinical characteristics in melanoma: a population-based study. Cancer Med. 2016 Nov; 5(11):3336-3345. PMID: 27748080.
        View in: PubMed
      11. Amos CI, Dennis J, Wang Z, Byun J, Schumacher FR, Gayther SA, Casey G, Hunter DJ, Sellers TA, Gruber S, Dunning AM, Michailidou K, Fachal L, Doheny K, Spurdle AB, Li Y, Xiao X, Romm J, Pugh E, Coetzee GA, Hazelett DJ, Bojesen SE, Caga-Anan C, Haiman CA, Kamal A, Luccarini C, Tessier D, Vincent D, Bacot F, Van Den Berg DJ, Nelson S, Demetriades S, Goldgar DE, Couch FJ, Forman JL, Giles GG, Conti DV, Bickeböller H, Risch A, Waldenberger M, Brüske-Hohlfeld I, Hicks BD, Ling H, McGuffog L, Lee A, Kuchenbaecker K, Soucy P, Manz J, Cunningham JM, Butterbach K, Kote-Jarai Z, Kraft P, FitzGerald L, Lindström S, Adams M, McKay JD, Phelan CM, Benlloch S, Kelemen LE, Brennan P, Riggan M, O'Mara TA, Shen H, Shi Y, Thompson DJ, Goodman MT, Nielsen SF, Berchuck A, Laboissiere S, Schmit SL, Shelford T, Edlund CK, Taylor JA, Field JK, Park SK, Offit K, Thomassen M, Schmutzler R, Ottini L, Hung RJ, Marchini J, Amin Al Olama A, Peters U, Eeles RA, Seldin MF, Gillanders E, Seminara D, Antoniou AC, Pharoah PD, Chenevix-Trench G, Chanock SJ, Simard J, Easton DF. The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers. Cancer Epidemiol Biomarkers Prev. 2017 Jan; 26(1):126-135. PMID: 27697780.
        View in: PubMed
      12. Karami S, Han Y, Pande M, Cheng I, Rudd J, Pierce BL, Nutter EL, Schumacher FR, Kote-Jarai Z, Lindstrom S, Witte JS, Fang S, Han J, Kraft P, Hunter DJ, Song F, Hung RJ, McKay J, Gruber S, Chanock SJ, Risch A, Shen H, Haiman CA, Boardman L, Ulrich CM, Casey G, Peters U, Amin Al Olama A, Berchuck A, Berndt SI, Bezieau S, Brennan P, Brenner H, Brinton L, Caporaso N, Chan AT, Chang-Claude J, Christiani DC, Cunningham JM, Easton D, Eeles RA, Eisen T, Gala M, Gallinger SJ, Gayther SA, Goode EL, Grönberg H, Henderson BE, Houlston R, Joshi AD, Küry S, Landi MT, Le Marchand L, Muir K, Newcomb PA, Permuth-Wey J, Pharoah P, Phelan C, Potter JD, Ramus SJ, Risch H, Schildkraut J, Slattery ML, Song H, Wentzensen N, White E, Wiklund F, Zanke BW, Sellers TA, Zheng W, Chatterjee N, Amos CI, Doherty JA. Telomere structure and maintenance gene variants and risk of five cancer types. Int J Cancer. 2016 Dec 15; 139(12):2655-2670. PMID: 27459707.
        View in: PubMed
      13. Khankari NK, Shu XO, Wen W, Kraft P, Lindström S, Peters U, Schildkraut J, Schumacher F, Bofetta P, Risch A, Bickeböller H, Amos CI, Easton D, Eeles RA, Gruber S, Haiman CA, Hunter DJ, Chanock SJ, Pierce BL, Zheng W. Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses. PLoS Med. 2016 Sep; 13(9):e1002118. PMID: 27598322; PMCID: PMC5012582.
      14. Gao C, Patel CJ, Michailidou K, Peters U, Gong J, Schildkraut J, Schumacher FR, Zheng W, Boffetta P, Stucker I, Willett W, Gruber S, Easton DF, Hunter DJ, Sellers TA, Haiman C, Henderson BE, Hung RJ, Amos C, Pierce BL, Lindström S, Kraft P. Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer. Int J Epidemiol. 2016 Jun; 45(3):896-908. PMID: 27427428.
        View in: PubMed
      15. Taylor NJ, Thomas NE, Anton-Culver H, Armstrong BK, Begg CB, Busam KJ, Cust AE, Dwyer T, From L, Gallagher RP, Gruber S, Nishri DE, Orlow I, Rosso S, Venn AJ, Zanetti R, Berwick M, Kanetsky PA. Nevus count associations with pigmentary phenotype, histopathological melanoma characteristics and survival from melanoma. Int J Cancer. 2016 Sep 15; 139(6):1217-22. PMID: 27101944; PMCID: PMC4939099 [Available on 09/15/17].
      16. Rozek LS, Schmit SL, Greenson JK, Tomsho LP, Rennert HS, Rennert G, Gruber S. Tumor-Infiltrating Lymphocytes, Crohn's-Like Lymphoid Reaction, and Survival From Colorectal Cancer. J Natl Cancer Inst. 2016 Aug; 108(8). PMID: 27172903; PMCID: PMC5017930 [Available on 08/01/17].
      17. Fehringer G, Kraft P, Pharoah PD, Eeles RA, Chatterjee N, Schumacher FR, Schildkraut JM, Lindström S, Brennan P, Bickeböller H, Houlston RS, Landi MT, Caporaso N, Risch A, Amin Al Olama A, Berndt SI, Giovannucci EL, Grönberg H, Kote-Jarai Z, Ma J, Muir K, Stampfer MJ, Stevens VL, Wiklund F, Willett WC, Goode EL, Permuth JB, Risch HA, Reid BM, Bezieau S, Brenner H, Chan AT, Chang-Claude J, Hudson TJ, Kocarnik JK, Newcomb PA, Schoen RE, Slattery ML, White E, Adank MA, Ahsan H, Aittomäki K, Baglietto L, Blomquist C, Canzian F, Czene K, Dos-Santos-Silva I, Eliassen AH, Figueroa JD, Flesch-Janys D, Fletcher O, Garcia-Closas M, Gaudet MM, Johnson N, Hall P, Hazra A, Hein R, Hofman A, Hopper JL, Irwanto A, Johansson M, Kaaks R, Kibriya MG, Lichtner P, Liu J, Lund E, Makalic E, Meindl A, Müller-Myhsok B, Muranen TA, Nevanlinna H, Peeters PH, Peto J, Prentice RL, Rahman N, Sanchez MJ, Schmidt DF, Schmutzler RK, Southey MC, Tamimi R, Travis RC, Turnbull C, Uitterlinden AG, Wang Z, Whittemore AS, Yang XR, Zheng W, Buchanan DD, Casey G, Conti DV, Edlund CK, Gallinger S, Haile RW, Jenkins M, Le Marchand L, Li L, Lindor NM, Schmit SL, Thibodeau SN, Woods MO, Rafnar T, Gudmundsson J, Stacey SN, Stefansson K, Sulem P, Chen YA, Tyrer JP, Christiani DC, Wei Y, Shen H, Hu Z, Shu XO, Shiraishi K, Takahashi A, Bossé Y, Obeidat M, Nickle D, Timens W, Freedman ML, Li Q, Seminara D, Chanock SJ, Gong J, Peters U, Gruber S, Amos CI, Sellers TA, Easton DF, Hunter DJ, Haiman CA, Henderson BE, Hung RJ. Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. Cancer Res. 2016 Sep 01; 76(17):5103-14. PMID: 27197191; PMCID: PMC5010493 [Available on 03/01/17].
      18. Schmit SL, Rennert HS, Rennert G, Gruber S. Coffee Consumption and the Risk of Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2016 04; 25(4):634-9. PMID: 27196095; PMCID: PMC4874555 [Available on 04/01/17].
      19. Zeng C, Matsuda K, Jia WH, Chang J, Kweon SS, Xiang YB, Shin A, Jee SH, Kim DH, Zhang B, Cai Q, Guo X, Long J, Wang N, Courtney R, Pan ZZ, Wu C, Takahashi A, Shin MH, Matsuo K, Matsuda F, Gao YT, Oh JH, Kim S, Jung KJ, Ahn YO, Ren Z, Li HL, Wu J, Shi J, Wen W, Yang G, Li B, Ji BT, Brenner H, Schoen RE, Küry S, Gruber S, Schumacher FR, Stenzel SL, Casey G, Hopper JL, Jenkins MA, Kim HR, Jeong JY, Park JW, Tajima K, Cho SH, Kubo M, Shu XO, Lin D, Zeng YX, Zheng W. Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk. Gastroenterology. 2016 Jun; 150(7):1633-1645. PMID: 26965516; PMCID: PMC4909543 [Available on 06/01/17].
      20. Gibbs DC, Orlow I, Bramson JI, Kanetsky PA, Luo L, Kricker A, Armstrong BK, Anton-Culver H, Gruber S, Marrett LD, Gallagher RP, Zanetti R, Rosso S, Dwyer T, Sharma A, La Pilla E, From L, Busam KJ, Cust AE, Ollila DW, Begg CB, Berwick M, Thomas NE. Association of Interferon Regulatory Factor-4 Polymorphism rs12203592 With Divergent Melanoma Pathways. J Natl Cancer Inst. 2016 Jul; 108(7). PMID: 26857527; PMCID: PMC4948568 [Available on 07/01/17].
      21. Ricker C, Culver JO, Lowstuter K, Sturgeon D, Sturgeon JD, Chanock CR, Gauderman WJ, McDonnell KJ, Idos GE, Gruber S. Increased yield of actionable mutations using multi-gene panels to assess hereditary cancer susceptibility in an ethnically diverse clinical cohort. Cancer Genet. 2016 Apr; 209(4):130-7. PMID: 26908360; PMCID: PMC4835267 [Available on 04/01/17].
      22. Markowitz SD, Nock NL, Schmit SL, Stadler ZK, Joseph V, Zhang L, Willis JE, Scacheri P, Veigl M, Adams MD, Raskin L, Sullivan JF, Stratton K, Shia J, Ellis N, Rennert HS, Manschreck C, Li L, Offit K, Elston RC, Rennert G, Gruber S. A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis. PLoS One. 2016; 11(1):e0146435. PMID: 26751797; PMCID: PMC4709047.
      23. Boonstra PS, Mukherjee B, Gruber S, Ahn J, Schmit SL, Chatterjee N. Tests for Gene-Environment Interactions and Joint Effects With Exposure Misclassification. Am J Epidemiol. 2016 Feb 01; 183(3):237-47. PMID: 26755675; PMCID: PMC4724093 [Available on 02/01/17].
      24. McDonnell KJ, Gallanis GT, Heller KA, Melas M, Idos GE, Culver JO, Martin SE, Peng DH, Gruber S. A novel BAP1 mutation is associated with melanocytic neoplasms and thyroid cancer. Cancer Genet. 2016 Mar; 209(3):75-81. PMID: 26774355.
        View in: PubMed
      25. Scarbrough PM, Weber RP, Iversen ES, Brhane Y, Amos CI, Kraft P, Hung RJ, Sellers TA, Witte JS, Pharoah P, Henderson BE, Gruber S, Hunter DJ, Garber JE, Joshi AD, McDonnell K, Easton DF, Eeles R, Kote-Jarai Z, Muir K, Doherty JA, Schildkraut JM. A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2016 Jan; 25(1):193-200. PMID: 26637267; PMCID: PMC4713268.
      26. Schumacher FR, Schmit SL, Jiao S, Edlund CK, Wang H, Zhang B, Hsu L, Huang SC, Fischer CP, Harju JF, Idos GE, Lejbkowicz F, Manion FJ, McDonnell K, McNeil CE, Melas M, Rennert HS, Shi W, Thomas DC, Van Den Berg DJ, Hutter CM, Aragaki AK, Butterbach K, Caan BJ, Carlson CS, Chanock SJ, Curtis KR, Fuchs CS, Gala M, Giovannucci EL, Gogarten SM, Hayes RB, Henderson B, Hunter DJ, Jackson RD, Kolonel LN, Kooperberg C, Küry S, LaCroix A, Laurie CC, Laurie CA, Lemire M, Levine D, Ma J, Makar KW, Qu C, Taverna D, Ulrich CM, Wu K, Kono S, West DW, Berndt SI, Bezieau S, Brenner H, Campbell PT, Chan AT, Chang-Claude J, Coetzee GA, Conti DV, Duggan D, Figueiredo JC, Fortini BK, Gallinger SJ, Gauderman WJ, Giles G, Green R, Haile R, Harrison TA, Hoffmeister M, Hopper JL, Hudson TJ, Jacobs E, Iwasaki M, Jee SH, Jenkins M, Jia WH, Joshi A, Li L, Lindor NM, Matsuo K, Moreno V, Mukherjee B, Newcomb PA, Potter JD, Raskin L, Rennert G, Rosse S, Severi G, Schoen RE, Seminara D, Shu XO, Slattery ML, Tsugane S, White E, Xiang YB, Zanke BW, Zheng W, Le Marchand L, Casey G, Gruber S, Peters U. Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nat Commun. 2015 Oct 26; 6:8739. PMID: 26498495.
        View in: PubMed
      27. Hung RJ, Ulrich CM, Goode EL, Brhane Y, Muir K, Chan AT, Marchand LL, Schildkraut J, Witte JS, Eeles R, Boffetta P, Spitz MR, Poirier JG, Rider DN, Fridley BL, Chen Z, Haiman C, Schumacher F, Easton DF, Landi MT, Brennan P, Houlston R, Christiani DC, Field JK, Bickeböller H, Risch A, Kote-Jarai Z, Wiklund F, Grönberg H, Chanock S, Berndt SI, Kraft P, Lindström S, Al Olama AA, Song H, Phelan C, Wentzensen N, Peters U, Slattery ML, Sellers TA, Casey G, Gruber S, Hunter DJ, Amos CI, Henderson B. Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer. J Natl Cancer Inst. 2015 Nov; 107(11). PMID: 26319099; PMCID: PMC4675100 [Available on 11/01/16].
      28. Zhang C, Doherty JA, Burgess S, Hung RJ, Lindström S, Kraft P, Gong J, Amos CI, Sellers TA, Monteiro AN, Chenevix-Trench G, Bickeböller H, Risch A, Brennan P, Mckay JD, Houlston RS, Landi MT, Timofeeva MN, Wang Y, Heinrich J, Kote-Jarai Z, Eeles RA, Muir K, Wiklund F, Grönberg H, Berndt SI, Chanock SJ, Schumacher F, Haiman CA, Henderson BE, Amin Al Olama A, Andrulis IL, Hopper JL, Chang-Claude J, John EM, Malone KE, Gammon MD, Ursin G, Whittemore AS, Hunter DJ, Gruber S, Knight JA, Hou L, Le Marchand L, Newcomb PA, Hudson TJ, Chan AT, Li L, Woods MO, Ahsan H, Pierce BL. Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study. Hum Mol Genet. 2015 Sep 15; 24(18):5356-66. PMID: 26138067; PMCID: PMC4550826.
      29. Thomas NE, Edmiston SN, Alexander A, Groben PA, Parrish E, Kricker A, Armstrong BK, Anton-Culver H, Gruber S, From L, Busam KJ, Hao H, Orlow I, Kanetsky PA, Luo L, Reiner AS, Paine S, Frank JS, Bramson JI, Marrett LD, Gallagher RP, Zanetti R, Rosso S, Dwyer T, Cust AE, Ollila DW, Begg CB, Berwick M, Conway K. Association Between NRAS and BRAF Mutational Status and Melanoma-Specific Survival Among Patients With Higher-Risk Primary Melanoma. JAMA Oncol. 2015 Jun; 1(3):359-68. PMID: 26146664; PMCID: PMC4486299.
      30. Gibbs DC, Orlow I, Kanetsky PA, Luo L, Kricker A, Armstrong BK, Anton-Culver H, Gruber S, Marrett LD, Gallagher RP, Zanetti R, Rosso S, Dwyer T, Sharma A, La Pilla E, From L, Busam KJ, Cust AE, Ollila DW, Begg CB, Berwick M, Thomas NE. Inherited genetic variants associated with occurrence of multiple primary melanoma. Cancer Epidemiol Biomarkers Prev. 2015 Jun; 24(6):992-7. PMID: 25837821; PMCID: PMC4452425.
      31. Taylor NJ, Busam KJ, From L, Groben PA, Anton-Culver H, Cust AE, Begg CB, Dwyer T, Gallagher RP, Gruber S, Orlow I, Rosso S, Thomas NE, Zanetti R, Rebbeck TR, Berwick M, Kanetsky PA. Inherited variation at MC1R and histological characteristics of primary melanoma. PLoS One. 2015; 10(3):e0119920. PMID: 25790105; PMCID: PMC4366050.
      32. Li L, Hamel N, Baker K, McGuffin MJ, Couillard M, Gologan A, Marcus VA, Chodirker B, Chudley A, Stefanovici C, Durandy A, Hegele RA, Feng BJ, Goldgar DE, Zhu J, De Rosa M, Gruber S, Wimmer K, Young B, Chong G, Tischkowitz MD, Foulkes WD. A homozygous PMS2 founder mutation with an attenuated constitutional mismatch repair deficiency phenotype. J Med Genet. 2015 May; 52(5):348-52. PMID: 25691505.
        View in: PubMed
      33. Stoffel EM, Mangu PB, Gruber S, Hamilton SR, Kalady MF, Lau MW, Lu KH, Roach N, Limburg PJ. Hereditary colorectal cancer syndromes: American Society of Clinical Oncology Clinical Practice Guideline endorsement of the familial risk-colorectal cancer: European Society for Medical Oncology Clinical Practice Guidelines. J Clin Oncol. 2015 Jan 10; 33(2):209-17. PMID: 25452455.
        View in: PubMed
      34. Thomas NE, Kricker A, Waxweiler WT, Dillon PM, Busman KJ, From L, Groben PA, Armstrong BK, Anton-Culver H, Gruber S, Marrett LD, Gallagher RP, Zanetti R, Rosso S, Dwyer T, Venn A, Kanetsky PA, Orlow I, Paine S, Ollila DW, Reiner AS, Luo L, Hao H, Frank JS, Begg CB, Berwick M. Comparison of clinicopathologic features and survival of histopathologically amelanotic and pigmented melanomas: a population-based study. JAMA Dermatol. 2014 Dec; 150(12):1306-314. PMID: 25162299; PMCID: PMC4262611.
      35. Everett JN, Raymond VM, Dandapani M, Marvin M, Kohlmann W, Chittenden A, Koeppe E, Gustafson SL, Else T, Fullen DR, Johnson TM, Syngal S, Gruber S, Stoffel EM. Screening for germline mismatch repair mutations following diagnosis of sebaceous neoplasm. JAMA Dermatol. 2014 Dec; 150(12):1315-21. PMID: 25006859; PMCID: PMC4977578.
      36. Taylor NJ, Reiner AS, Begg CB, Cust AE, Busam KJ, Anton-Culver H, Dwyer T, From L, Gallagher RP, Gruber S, Rosso S, White KA, Zanetti R, Orlow I, Thomas NE, Rebbeck TR, Berwick M, Kanetsky PA. Inherited variation at MC1R and ASIP and association with melanoma-specific survival. Int J Cancer. 2015 Jun 01; 136(11):2659-67. PMID: 25382380; PMCID: PMC4361274.
      37. Schmit SL, Gollub J, Shapero MH, Huang SC, Rennert HS, Finn A, Rennert G, Gruber S. MicroRNA polymorphisms and risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2015 Jan; 24(1):65-72. PMID: 25342389; PMCID: PMC4867219.
      38. Wang H, Burnett T, Kono S, Haiman CA, Iwasaki M, Wilkens LR, Loo LW, Van Den Berg D, Kolonel LN, Henderson BE, Keku TO, Sandler RS, Signorello LB, Blot WJ, Newcomb PA, Pande M, Amos CI, West DW, Bézieau S, Berndt SI, Zanke BW, Hsu L, Lindor NM, Haile RW, Hopper JL, Jenkins MA, Gallinger S, Casey G, Stenzel SL, Schumacher FR, Peters U, Gruber S, Tsugane S, Stram DO, Le Marchand L. Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. Nat Commun. 2014 Aug 08; 5:4613. PMID: 25105248; PMCID: PMC4180879.
      39. Berwick M, Reiner AS, Paine S, Armstrong BK, Kricker A, Goumas C, Cust AE, Thomas NE, Groben PA, From L, Busam K, Orlow I, Marrett LD, Gallagher RP, Gruber S, Anton-Culver H, Rosso S, Zanetti R, Kanetsky PA, Dwyer T, Venn A, Lee-Taylor J, Begg CB. Sun exposure and melanoma survival: a GEM study. Cancer Epidemiol Biomarkers Prev. 2014 Oct; 23(10):2145-52. PMID: 25069694; PMCID: PMC4184941.
      40. Schmit SL, Schumacher FR, Edlund CK, Conti DV, Raskin L, Lejbkowicz F, Pinchev M, Rennert HS, Jenkins MA, Hopper JL, Buchanan DD, Lindor NM, Le Marchand L, Gallinger S, Haile RW, Newcomb PA, Huang SC, Rennert G, Casey G, Gruber S. A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study. Carcinogenesis. 2014 Nov; 35(11):2512-9. PMID: 25023989; PMCID: PMC4271131.
      41. Stenzel SL, Ahn J, Boonstra PS, Gruber S, Mukherjee B. The impact of exposure-biased sampling designs on detection of gene-environment interactions in case-control studies with potential exposure misclassification. Eur J Epidemiol. 2015 May; 30(5):413-23. PMID: 24894824; PMCID: PMC4256150.
      42. Zhang B, Jia WH, Matsuda K, Kweon SS, Matsuo K, Xiang YB, Shin A, Jee SH, Kim DH, Cai Q, Long J, Shi J, Wen W, Yang G, Zhang Y, Li C, Li B, Guo Y, Ren Z, Ji BT, Pan ZZ, Takahashi A, Shin MH, Matsuda F, Gao YT, Oh JH, Kim S, Ahn YO, Chan AT, Chang-Claude J, Slattery ML, Gruber S, Schumacher FR, Stenzel SL, Casey G, Kim HR, Jeong JY, Park JW, Li HL, Hosono S, Cho SH, Kubo M, Shu XO, Zeng YX, Zheng W. Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. Nat Genet. 2014 Jun; 46(6):533-42. PMID: 24836286; PMCID: PMC4068797.
      43. Else T, Marvin ML, Everett JN, Gruber S, Arts HA, Stoffel EM, Auchus RJ, Raymond VM. The clinical phenotype of SDHC-associated hereditary paraganglioma syndrome (PGL3). J Clin Endocrinol Metab. 2014 Aug; 99(8):E1482-6. PMID: 24758179; PMCID: PMC4121019.
      44. Berwick M, MacArthur J, Orlow I, Kanetsky P, Begg CB, Luo L, Reiner A, Sharma A, Armstrong BK, Kricker A, Cust AE, Marrett LD, Gruber S, Anton-Culver H, Zanetti R, Rosso S, Gallagher RP, Dwyer T, Venn A, Busam K, From L, White K, Thomas NE. MITF E318K's effect on melanoma risk independent of, but modified by, other risk factors. Pigment Cell Melanoma Res. 2014 May; 27(3):485-8. PMID: 24406078; PMCID: PMC3988207.
      45. Glatz AC, Purrington KS, Klinger A, King AR, Hellinger J, Zhu X, Gruber S, Gruber PJ. Cumulative exposure to medical radiation for children requiring surgery for congenital heart disease. J Pediatr. 2014 Apr; 164(4):789-794.e10. PMID: 24321535.
        View in: PubMed
      46. Thomas NE, Busam KJ, From L, Kricker A, Armstrong BK, Anton-Culver H, Gruber S, Gallagher RP, Zanetti R, Rosso S, Dwyer T, Venn A, Kanetsky PA, Groben PA, Hao H, Orlow I, Reiner AS, Luo L, Paine S, Ollila DW, Wilcox H, Begg CB, Berwick M. Tumor-infiltrating lymphocyte grade in primary melanomas is independently associated with melanoma-specific survival in the population-based genes, environment and melanoma study. J Clin Oncol. 2013 Nov 20; 31(33):4252-9. PMID: 24127443; PMCID: PMC3821014.
      47. Porenta SR, Ko YA, Gruber S, Mukherjee B, Baylin A, Ren J, Djuric Z. Interaction of fatty acid genotype and diet on changes in colonic fatty acids in a Mediterranean diet intervention study. Cancer Prev Res (Phila). 2013 Nov; 6(11):1212-21. PMID: 24022589; PMCID: PMC3840911.
      48. Raskin L, Dakubo JC, Palaski N, Greenson JK, Gruber S. Distinct molecular features of colorectal cancer in Ghana. Cancer Epidemiol. 2013 Oct; 37(5):556-61. PMID: 23962701; PMCID: PMC4267222.
      49. Raymond VM, Long JM, Everett JN, Caoili EM, Gruber S, Stoffel EM, Giordano TJ, Hammer GD, Else T. An oncocytic adrenal tumour in a patient with Birt-Hogg-Dubé syndrome. Clin Endocrinol (Oxf). 2014 Jun; 80(6):925-7. PMID: 23848572; PMCID: PMC3893308.
      50. Kricker A, Armstrong BK, Goumas C, Thomas NE, From L, Busam K, Kanetsky PA, Gallagher RP, Marrett LD, Groben PA, Gruber S, Anton-Culver H, Rosso S, Dwyer T, Berwick M. Survival for patients with single and multiple primary melanomas: the genes, environment, and melanoma study. JAMA Dermatol. 2013 Aug; 149(8):921-7. PMID: 23784017; PMCID: PMC3815536.
      51. Raymond VM, Everett JN, Furtado LV, Gustafson SL, Jungbluth CR, Gruber S, Hammer GD, Stoffel EM, Greenson JK, Giordano TJ, Else T. Adrenocortical carcinoma is a lynch syndrome-associated cancer. J Clin Oncol. 2013 Aug 20; 31(24):3012-8. PMID: 23752102; PMCID: PMC3739861.
      52. Raskin L, Fullen DR, Giordano TJ, Thomas DG, Frohm ML, Cha KB, Ahn J, Mukherjee B, Johnson TM, Gruber S. Transcriptome profiling identifies HMGA2 as a biomarker of melanoma progression and prognosis. J Invest Dermatol. 2013 Nov; 133(11):2585-2592. PMID: 23633021; PMCID: PMC4267221.
      53. Raymond VM, Mukherjee B, Wang F, Huang SC, Stoffel EM, Kastrinos F, Syngal S, Cooney KA, Gruber S. Elevated risk of prostate cancer among men with Lynch syndrome. J Clin Oncol. 2013 May 10; 31(14):1713-8. PMID: 23530095; PMCID: PMC3641694.
      54. Anderson BR, Stevens KN, Nicolson SC, Gruber S, Spray TL, Wernovsky G, Gruber PJ. Contemporary outcomes of surgical ventricular septal defect closure. J Thorac Cardiovasc Surg. 2013 Mar; 145(3):641-7. PMID: 23414985.
        View in: PubMed
      55. Ahn J, Mukherjee B, Gruber S, Ghosh M. BAYESIAN SEMIPARAMETRIC ANALYSIS FOR TWO-PHASE STUDIES OF GENE-ENVIRONMENT INTERACTION. Ann Appl Stat. 2013 Mar; 7(1):543-569. PMID: 24587840.
        View in: PubMed
      56. Jiao S, Hsu L, Berndt S, Bézieau S, Brenner H, Buchanan D, Caan BJ, Campbell PT, Carlson CS, Casey G, Chan AT, Chang-Claude J, Chanock S, Conti DV, Curtis KR, Duggan D, Gallinger S, Gruber S, Harrison TA, Hayes RB, Henderson BE, Hoffmeister M, Hopper JL, Hudson TJ, Hutter CM, Jackson RD, Jenkins MA, Kantor ED, Kolonel LN, Küry S, Le Marchand L, Lemire M, Newcomb PA, Potter JD, Qu C, Rosse SA, Schoen RE, Schumacher FR, Seminara D, Slattery ML, Ulrich CM, Zanke BW, Peters U. Genome-wide search for gene-gene interactions in colorectal cancer. PLoS One. 2012; 7(12):e52535. PMID: 23300701; PMCID: PMC3530500.
      57. Peters U, Jiao S, Schumacher FR, Hutter CM, Aragaki AK, Baron JA, Berndt SI, Bézieau S, Brenner H, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Casey G, Chan AT, Chang-Claude J, Chanock SJ, Chen LS, Coetzee GA, Coetzee SG, Conti DV, Curtis KR, Duggan D, Edwards T, Fuchs CS, Gallinger S, Giovannucci EL, Gogarten SM, Gruber S, Haile RW, Harrison TA, Hayes RB, Henderson BE, Hoffmeister M, Hopper JL, Hudson TJ, Hunter DJ, Jackson RD, Jee SH, Jenkins MA, Jia WH, Kolonel LN, Kooperberg C, Küry S, Lacroix AZ, Laurie CC, Laurie CA, Le Marchand L, Lemire M, Levine D, Lindor NM, Liu Y, Ma J, Makar KW, Matsuo K, Newcomb PA, Potter JD, Prentice RL, Qu C, Rohan T, Rosse SA, Schoen RE, Seminara D, Shrubsole M, Shu XO, Slattery ML, Taverna D, Thibodeau SN, Ulrich CM, White E, Xiang Y, Zanke BW, Zeng YX, Zhang B, Zheng W, Hsu L. Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology. 2013 Apr; 144(4):799-807.e24. PMID: 23266556; PMCID: PMC3636812.
      58. Raymond VM, Else T, Everett JN, Long JM, Gruber S, Hammer GD. Prevalence of germline TP53 mutations in a prospective series of unselected patients with adrenocortical carcinoma. J Clin Endocrinol Metab. 2013 Jan; 98(1):E119-25. PMID: 23175693; PMCID: PMC3537086.
      59. Lejbkowicz F, Cohen I, Barnett-Griness O, Pinchev M, Poynter J, Gruber S, Rennert G. Common MUTYH mutations and colorectal cancer risk in multiethnic populations. Fam Cancer. 2012 Sep; 11(3):329-35. PMID: 22371070.
        View in: PubMed
      60. Yurgelun MB, Mercado R, Rosenblatt M, Dandapani M, Kohlmann W, Conrad P, Blanco A, Shannon KM, Chung DC, Terdiman J, Gruber S, Garber JE, Syngal S, Stoffel EM. Impact of genetic testing on endometrial cancer risk-reducing practices in women at risk for Lynch syndrome. Gynecol Oncol. 2012 Dec; 127(3):544-51. PMID: 22940489; PMCID: PMC3496001.
      61. Samadder NJ, Gornick M, Everett J, Greenson JK, Gruber S. Inflammatory bowel disease and familial adenomatous polyposis. J Crohns Colitis. 2013 Apr; 7(3):e103-7. PMID: 22809634.
        View in: PubMed
      62. Pineda M, Mur P, Iniesta MD, Borràs E, Campos O, Vargas G, Iglesias S, Fernández A, Gruber S, Lázaro C, Brunet J, Navarro M, Blanco I, Capellá G. MLH1 methylation screening is effective in identifying epimutation carriers. Eur J Hum Genet. 2012 Dec; 20(12):1256-64. PMID: 22763379; PMCID: PMC3499751.
      63. Mukherjee B, Delancey JO, Raskin L, Everett J, Jeter J, Begg CB, Orlow I, Berwick M, Armstrong BK, Kricker A, Marrett LD, Millikan RC, Culver HA, Rosso S, Zanetti R, Kanetsky PA, From L, Gruber S. Risk of non-melanoma cancers in first-degree relatives of CDKN2A mutation carriers. J Natl Cancer Inst. 2012 Jun 20; 104(12):953-6. PMID: 22534780; PMCID: PMC3379723.
      64. Masciari S, Dillon DA, Rath M, Robson M, Weitzel JN, Balmana J, Gruber S, Ford JM, Euhus D, Lebensohn A, Telli M, Pochebit SM, Lypas G, Garber JE. Breast cancer phenotype in women with TP53 germline mutations: a Li-Fraumeni syndrome consortium effort. Breast Cancer Res Treat. 2012 Jun; 133(3):1125-30. PMID: 22392042; PMCID: PMC3709568.
      65. Raymond VM, Herron CM, Giordano TJ, Gruber S. Familial renal cancer as an indicator of hereditary leiomyomatosis and renal cell cancer syndrome. Fam Cancer. 2012 Mar; 11(1):115-21. PMID: 22127509.
        View in: PubMed
      66. Gausachs M, Mur P, Corral J, Pineda M, González S, Benito L, Menéndez M, Espinàs JA, Brunet J, Iniesta MD, Gruber S, Lázaro C, Blanco I, Capellá G. MLH1 promoter hypermethylation in the analytical algorithm of Lynch syndrome: a cost-effectiveness study. Eur J Hum Genet. 2012 Jul; 20(7):762-8. PMID: 22274583; PMCID: PMC3376264.
      67. Cote ML, Kam A, Chang CY, Raskin L, Reding KW, Cho KR, Gruber S, Ali-Fehmi R. A pilot study of microsatellite instability and endometrial cancer survival in white and African American women. Int J Gynecol Pathol. 2012 Jan; 31(1):66-72. PMID: 22123725.
        View in: PubMed
      68. Mukherjee B, Ahn J, Gruber S, Chatterjee N. Testing gene-environment interaction in large-scale case-control association studies: possible choices and comparisons. Am J Epidemiol. 2012 Feb 01; 175(3):177-90. PMID: 22199027; PMCID: PMC3286201.
      69. Roychowdhury S, Iyer MK, Robinson DR, Lonigro RJ, Wu YM, Cao X, Kalyana-Sundaram S, Sam L, Balbin OA, Quist MJ, Barrette T, Everett J, Siddiqui J, Kunju LP, Navone N, Araujo JC, Troncoso P, Logothetis CJ, Innis JW, Smith DC, Lao CD, Kim SY, Roberts JS, Gruber S, Pienta KJ, Talpaz M, Chinnaiyan AM. Personalized oncology through integrative high-throughput sequencing: a pilot study. Sci Transl Med. 2011 Nov 30; 3(111):111ra121. PMID: 22133722; PMCID: PMC3476478.
      70. Maxwell CA, Benítez J, Gómez-Baldó L, Osorio A, Bonifaci N, Fernández-Ramires R, Costes SV, Guinó E, Chen H, Evans GJ, Mohan P, Català I, Petit A, Aguilar H, Villanueva A, Aytes A, Serra-Musach J, Rennert G, Lejbkowicz F, Peterlongo P, Manoukian S, Peissel B, Ripamonti CB, Bonanni B, Viel A, Allavena A, Bernard L, Radice P, Friedman E, Kaufman B, Laitman Y, Dubrovsky M, Milgrom R, Jakubowska A, Cybulski C, Gorski B, Jaworska K, Durda K, Sukiennicki G, Lubinski J, Shugart YY, Domchek SM, Letrero R, Weber BL, Hogervorst FB, Rookus MA, Collee JM, Devilee P, Ligtenberg MJ, Luijt RB, Aalfs CM, Waisfisz Q, Wijnen J, Roozendaal CE, Easton DF, Peock S, Cook M, Oliver C, Frost D, Harrington P, Evans DG, Lalloo F, Eeles R, Izatt L, Chu C, Eccles D, Douglas F, Brewer C, Nevanlinna H, Heikkinen T, Couch FJ, Lindor NM, Wang X, Godwin AK, Caligo MA, Lombardi G, Loman N, Karlsson P, Ehrencrona H, Wachenfeldt Av, Barkardottir RB, Hamann U, Rashid MU, Lasa A, Caldés T, Andrés R, Schmitt M, Assmann V, Stevens K, Offit K, Curado J, Tilgner H, Guigó R, Aiza G, Brunet J, Castellsagué J, Martrat G, Urruticoechea A, Blanco I, Tihomirova L, Goldgar DE, Buys S, John EM, Miron A, Southey M, Daly MB, Schmutzler RK, Wappenschmidt B, Meindl A, Arnold N, Deissler H, Varon-Mateeva R, Sutter C, Niederacher D, Imyamitov E, Sinilnikova OM, Stoppa-Lyonne D, Mazoyer S, Verny-Pierre C, Castera L, de Pauw A, Bignon YJ, Uhrhammer N, Peyrat JP, Vennin P, Fert Ferrer S, Collonge-Rame MA, Mortemousque I, Spurdle AB, Beesley J, Chen X, Healey S, Barcellos-Hoff MH, Vidal M, Gruber S, Lázaro C, Capellá G, McGuffog L, Nathanson KL, Antoniou AC, Chenevix-Trench G, Fleisch MC, Moreno V, Pujana MA. Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. PLoS Biol. 2011 Nov; 9(11):e1001199. PMID: 22110403; PMCID: PMC3217025.
      71. Vilar E, Tabernero J, Gruber S. Micromanaging the classification of colon cancer: the role of the microRNAome. Clin Cancer Res. 2011 Dec 01; 17(23):7207-9. PMID: 22019515; PMCID: PMC3422018.
      72. Sanz-Pamplona R, Cordero D, Berenguer A, Lejbkowicz F, Rennert H, Salazar R, Biondo S, Sanjuan X, Pujana MA, Rozek L, Giordano TJ, Ben-Izhak O, Cohen HI, Trougouboff P, Bejhar J, Sova Y, Rennert G, Gruber S, Moreno V. Gene expression differences between colon and rectum tumors. Clin Cancer Res. 2011 Dec 01; 17(23):7303-12. PMID: 21976543; PMCID: PMC3229689.
      73. Murali R, Goumas C, Kricker A, From L, Busam KJ, Begg CB, Dwyer T, Gruber S, Kanetsky PA, Orlow I, Rosso S, Thomas NE, Berwick M, Scolyer RA, Armstrong BK. Clinicopathologic features of incident and subsequent tumors in patients with multiple primary cutaneous melanomas. Ann Surg Oncol. 2012 Mar; 19(3):1024-33. PMID: 21913010; PMCID: PMC3288399.
      74. Tomsic J, Liyanarachchi S, Hampel H, Morak M, Thomas BC, Raymond VM, Chittenden A, Schackert HK, Gruber S, Syngal S, Viel A, Holinski-Feder E, Thibodeau SN, de la Chapelle A. An American founder mutation in MLH1. Int J Cancer. 2012 May 01; 130(9):2088-95. PMID: 21671475; PMCID: PMC3266960.
      75. Berwick M, Begg CB, Armstrong BK, Reiner AS, Thomas NE, Cook LS, Orlow I, Kricker A, Marrett LD, Gruber S, Anton-Culver H, Millikan RC, Gallagher RP, Dwyer T, Rosso S, Kanetsky PA, Lee-Taylor J. Interaction of CDKN2A and sun exposure in the etiology of melanoma in the general population. J Invest Dermatol. 2011 Dec; 131(12):2500-3. PMID: 21833009; PMCID: PMC3213249.
      76. Peters U, Hutter CM, Hsu L, Schumacher FR, Conti DV, Carlson CS, Edlund CK, Haile RW, Gallinger S, Zanke BW, Lemire M, Rangrej J, Vijayaraghavan R, Chan AT, Hazra A, Hunter DJ, Ma J, Fuchs CS, Giovannucci EL, Kraft P, Liu Y, Chen L, Jiao S, Makar KW, Taverna D, Gruber S, Rennert G, Moreno V, Ulrich CM, Woods MO, Green RC, Parfrey PS, Prentice RL, Kooperberg C, Jackson RD, Lacroix AZ, Caan BJ, Hayes RB, Berndt SI, Chanock SJ, Schoen RE, Chang-Claude J, Hoffmeister M, Brenner H, Frank B, Bézieau S, Küry S, Slattery ML, Hopper JL, Jenkins MA, Le Marchand L, Lindor NM, Newcomb PA, Seminara D, Hudson TJ, Duggan DJ, Potter JD, Casey G. Meta-analysis of new genome-wide association studies of colorectal cancer risk. Hum Genet. 2012 Feb; 131(2):217-34. PMID: 21761138; PMCID: PMC3257356.
      77. Arthur AE, Duffy SA, Sanchez GI, Gruber S, Terrell JE, Hebert JR, Light E, Bradford CR, D'Silva NJ, Carey TE, Wolf GT, Peterson KE, Rozek LS. Higher micronutrient intake is associated with human papillomavirus-positive head and neck cancer: a case-only analysis. Nutr Cancer. 2011; 63(5):734-42. PMID: 21667401; PMCID: PMC3391594.
      78. Boonstra PS, Mukherjee B, Taylor JM, Nilbert M, Moreno V, Gruber S. Bayesian modeling for genetic anticipation in presence of mutational heterogeneity: a case study in Lynch syndrome. Biometrics. 2011 Dec; 67(4):1627-37. PMID: 21627626; PMCID: PMC3176998.
      79. Jeter JM, Bonner JD, Johnson TM, Gruber S. Nonsteroidal anti-inflammatory drugs and risk of melanoma. J Skin Cancer. 2011; 2011:598571. PMID: 21773038; PMCID: PMC3135212.
      80. Orlow I, Roy P, Reiner AS, Yoo S, Patel H, Paine S, Armstrong BK, Kricker A, Marrett LD, Millikan RC, Thomas NE, Gruber S, Anton-Culver H, Rosso S, Gallagher RP, Dwyer T, Kanetsky PA, Busam K, From L, Begg CB, Berwick M. Vitamin D receptor polymorphisms in patients with cutaneous melanoma. Int J Cancer. 2012 Jan 15; 130(2):405-18. PMID: 21365644; PMCID: PMC3135781.
      81. Marvin ML, Mazzoni SM, Herron CM, Edwards S, Gruber S, Petty EM. AXIN2-associated autosomal dominant ectodermal dysplasia and neoplastic syndrome. Am J Med Genet A. 2011 Apr; 155A(4):898-902. PMID: 21416598; PMCID: PMC3094478.
      82. Mukherjee B, Rennert G, Ahn J, Dishon S, Lejbkowicz F, Rennert HS, Shiovitz S, Moreno V, Gruber S. High risk of colorectal and endometrial cancer in Ashkenazi families with the MSH2 A636P founder mutation. Gastroenterology. 2011 Jun; 140(7):1919-26. PMID: 21419771; PMCID: PMC4835182.
      83. Bauer CM, Ray AM, Halstead-Nussloch BA, Dekker RG, Raymond VM, Gruber S, Cooney KA. Hereditary prostate cancer as a feature of Lynch syndrome. Fam Cancer. 2011 Mar; 10(1):37-42. PMID: 20872076; PMCID: PMC3089958.
      84. Rennert G, Pinchev M, Rennert HS, Gruber S. Use of bisphosphonates and reduced risk of colorectal cancer. J Clin Oncol. 2011 Mar 20; 29(9):1146-50. PMID: 21321296; PMCID: PMC3083870.
      85. Christensen KD, Roberts JS, Shalowitz DI, Everett JN, Kim SY, Raskin L, Gruber S. Disclosing individual CDKN2A research results to melanoma survivors: interest, impact, and demands on researchers. Cancer Epidemiol Biomarkers Prev. 2011 Mar; 20(3):522-9. PMID: 21307304; PMCID: PMC3833711.
      86. Vilar E, Bartnik CM, Stenzel SL, Raskin L, Ahn J, Moreno V, Mukherjee B, Iniesta MD, Morgan MA, Rennert G, Gruber S. MRE11 deficiency increases sensitivity to poly(ADP-ribose) polymerase inhibition in microsatellite unstable colorectal cancers. Cancer Res. 2011 Apr 01; 71(7):2632-42. PMID: 21300766; PMCID: PMC3407272.
      87. Shulman K, Cohen I, Barnett-Griness O, Kuten A, Gruber S, Lejbkowicz F, Rennert G. Clinical implications of UGT1A1*28 genotype testing in colorectal cancer patients. Cancer. 2011 Jul 15; 117(14):3156-62. PMID: 21287524; PMCID: PMC3117027.
      88. Yao L, Schiavi F, Cascon A, Qin Y, Inglada-Pérez L, King EE, Toledo RA, Ercolino T, Rapizzi E, Ricketts CJ, Mori L, Giacchè M, Mendola A, Taschin E, Boaretto F, Loli P, Iacobone M, Rossi GP, Biondi B, Lima-Junior JV, Kater CE, Bex M, Vikkula M, Grossman AB, Gruber S, Barontini M, Persu A, Castellano M, Toledo SP, Maher ER, Mannelli M, Opocher G, Robledo M, Dahia PL. Spectrum and prevalence of FP/TMEM127 gene mutations in pheochromocytomas and paragangliomas. JAMA. 2010 Dec 15; 304(23):2611-9. PMID: 21156949.
        View in: PubMed
      89. Dinh TA, Rosner BI, Atwood JC, Boland CR, Syngal S, Vasen HF, Gruber S, Burt RW. Health benefits and cost-effectiveness of primary genetic screening for Lynch syndrome in the general population. Cancer Prev Res (Phila). 2011 Jan; 4(1):9-22. PMID: 21088223; PMCID: PMC3793254.
      90. Samadder NJ, Mukherjee B, Huang SC, Ahn J, Rennert HS, Greenson JK, Rennert G, Gruber S. Risk of colorectal cancer in self-reported inflammatory bowel disease and modification of risk by statin and NSAID use. Cancer. 2011 Apr 15; 117(8):1640-8. PMID: 21472711; PMCID: PMC3117060.
      91. Boonstra PS, Gruber S, Raymond VM, Huang SC, Timshel S, Nilbert M, Mukherjee B. A review of statistical methods for testing genetic anticipation: looking for an answer in Lynch syndrome. Genet Epidemiol. 2010 Nov; 34(7):756-68. PMID: 20878717; PMCID: PMC3894615.
      92. Borràs E, Pineda M, Blanco I, Jewett EM, Wang F, Teulé A, Caldés T, Urioste M, Martínez-Bouzas C, Brunet J, Balmaña J, Torres A, Ramón y Cajal T, Sanz J, Pérez-Cabornero L, Castellví-Bel S, Alonso A, Lanas A, González S, Moreno V, Gruber S, Rosenberg NA, Mukherjee B, Lázaro C, Capellá G. MLH1 founder mutations with moderate penetrance in Spanish Lynch syndrome families. Cancer Res. 2010 Oct 01; 70(19):7379-91. PMID: 20858721.
        View in: PubMed
      93. Roberts JS, Shalowitz DI, Christensen KD, Everett JN, Kim SY, Raskin L, Gruber S. Returning individual research results: development of a cancer genetics education and risk communication protocol. J Empir Res Hum Res Ethics. 2010 Sep; 5(3):17-30. PMID: 20831418; PMCID: PMC3159194.
      94. Mukherjee B, Ahn J, Gruber S, Ghosh M, Chatterjee N. Case-control studies of gene-environment interaction: Bayesian design and analysis. Biometrics. 2010 Sep; 66(3):934-48. PMID: 19930190; PMCID: PMC3103064.
      95. Ahn J, Mukherjee B, Gruber S, Sinha S. Missing exposure data in stereotype regression model: application to matched case-control study with disease subclassification. Biometrics. 2011 Jun; 67(2):546-58. PMID: 20560931; PMCID: PMC3119773.
      96. Stevens KN, Hakonarson H, Kim CE, Doevendans PA, Koeleman BP, Mital S, Raue J, Glessner JT, Coles JG, Moreno V, Granger A, Gruber S, Gruber PJ. Common variation in ISL1 confers genetic susceptibility for human congenital heart disease. PLoS One. 2010 May 26; 5(5):e10855. PMID: 20520780; PMCID: PMC2877111.
      97. Greenwood CM, Sun S, Veenstra J, Hamel N, Niell B, Gruber S, Foulkes WD. How old is this mutation? - a study of three Ashkenazi Jewish founder mutations. BMC Genet. 2010 May 14; 11:39. PMID: 20470408; PMCID: PMC2889843.
      98. Daly MB, Axilbund JE, Buys S, Crawford B, Farrell CD, Friedman S, Garber JE, Goorha S, Gruber S, Hampel H, Kaklamani V, Kohlmann W, Kurian A, Litton J, Marcom PK, Nussbaum R, Offit K, Pal T, Pasche B, Pilarski R, Reiser G, Shannon KM, Smith JR, Swisher E, Weitzel JN. Genetic/familial high-risk assessment: breast and ovarian. J Natl Compr Canc Netw. 2010 May; 8(5):562-94. PMID: 20495085.
        View in: PubMed
      99. Castellsagué E, González S, Guinó E, Stevens KN, Borràs E, Raymond VM, Lázaro C, Blanco I, Gruber S, Capellá G. Allele-specific expression of APC in adenomatous polyposis families. Gastroenterology. 2010 Aug; 139(2):439-47, 447.e1. PMID: 20434453; PMCID: PMC2910837.
      100. Lipkin SM, Chao EC, Moreno V, Rozek LS, Rennert H, Pinchev M, Dizon D, Rennert G, Kopelovich L, Gruber S. Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer. Cancer Prev Res (Phila). 2010 May; 3(5):597-603. PMID: 20403997.
        View in: PubMed
      101. Stoffel EM, Mercado RC, Kohlmann W, Ford B, Grover S, Conrad P, Blanco A, Shannon KM, Powell M, Chung DC, Terdiman J, Gruber S, Syngal S. Prevalence and predictors of appropriate colorectal cancer surveillance in Lynch syndrome. Am J Gastroenterol. 2010 Aug; 105(8):1851-60. PMID: 20354509; PMCID: PMC3091484.
      102. Shiovitz S, Everett J, Huang SC, Orloff MS, Eng C, Gruber S. Head circumference in the clinical detection of PTEN hamartoma tumor syndrome in a clinic population at high-risk of breast cancer. Breast Cancer Res Treat. 2010 Nov; 124(2):459-65. PMID: 20349131.
        View in: PubMed
      103. Moorman PG, Iversen ES, Marcom PK, Marks JR, Wang F, Lee E, Ursin G, Rebbeck TR, Domchek SM, Arun B, Susswein L, Isaacs C, Garber JE, Visvanathan K, Griffin CA, Sutphen R, Brzosowicz J, Gruber S, Finkelstein DM, Schildkraut JM. Evaluation of established breast cancer risk factors as modifiers of BRCA1 or BRCA2: a multi-center case-only analysis. Breast Cancer Res Treat. 2010 Nov; 124(2):441-51. PMID: 20309627; PMCID: PMC2925060.
      104. Rennert G, Rennert HS, Pinchev M, Gruber S. A case-control study of levothyroxine and the risk of colorectal cancer. J Natl Cancer Inst. 2010 Apr 21; 102(8):568-72. PMID: 20305129; PMCID: PMC2857798.
      105. Rozek LS, Herron CM, Greenson JK, Moreno V, Capella G, Rennert G, Gruber S. Smoking, gender, and ethnicity predict somatic BRAF mutations in colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2010 Mar; 19(3):838-43. PMID: 20200438; PMCID: PMC2872124.
      106. Vilar E, Gruber S. Microsatellite instability in colorectal cancer-the stable evidence. Nat Rev Clin Oncol. 2010 Mar; 7(3):153-62. PMID: 20142816; PMCID: PMC3427139.
      107. Gornick MC, Castellsague X, Sanchez G, Giordano TJ, Vinco M, Greenson JK, Capella G, Raskin L, Rennert G, Gruber S, Moreno V. Human papillomavirus is not associated with colorectal cancer in a large international study. Cancer Causes Control. 2010 May; 21(5):737-43. PMID: 20087645; PMCID: PMC4269349.
      108. Burt RW, Barthel JS, Dunn KB, David DS, Drelichman E, Ford JM, Giardiello FM, Gruber S, Halverson AL, Hamilton SR, Ismail MK, Jasperson K, Lazenby AJ, Lynch PM, Martin EW, Mayer RJ, Ness RM, Provenzale D, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D. NCCN clinical practice guidelines in oncology. Colorectal cancer screening. J Natl Compr Canc Netw. 2010 Jan; 8(1):8-61. PMID: 20064289.
        View in: PubMed
      109. Kastrinos F, Mukherjee B, Tayob N, Wang F, Sparr J, Raymond VM, Bandipalliam P, Stoffel EM, Gruber S, Syngal S. Risk of pancreatic cancer in families with Lynch syndrome. JAMA. 2009 Oct 28; 302(16):1790-5. PMID: 19861671; PMCID: PMC4091624.
      110. Rennert G, Rennert HS, Pinchev M, Lavie O, Gruber S. Use of hormone replacement therapy and the risk of colorectal cancer. J Clin Oncol. 2009 Sep 20; 27(27):4542-7. PMID: 19704062; PMCID: PMC2754905.
      111. Grover S, Stoffel EM, Mercado RC, Ford BM, Kohlman WK, Shannon KM, Conrad PG, Blanco AM, Terdiman JP, Gruber S, Chung DC, Syngal S. Colorectal cancer risk perception on the basis of genetic test results in individuals at risk for Lynch syndrome. J Clin Oncol. 2009 Aug 20; 27(24):3981-6. PMID: 19620492; PMCID: PMC2734398.
      112. Stoffel E, Mukherjee B, Raymond VM, Tayob N, Kastrinos F, Sparr J, Wang F, Bandipalliam P, Syngal S, Gruber S. Calculation of risk of colorectal and endometrial cancer among patients with Lynch syndrome. Gastroenterology. 2009 Nov; 137(5):1621-7. PMID: 19622357; PMCID: PMC2767441.
      113. Roy S, Raskin L, Raymond VM, Thibodeau SN, Mody RJ, Gruber S. Pediatric duodenal cancer and biallelic mismatch repair gene mutations. Pediatr Blood Cancer. 2009 Jul; 53(1):116-20. PMID: 19283792.
        View in: PubMed
      114. Mayne ST, Gruber S. Emerging molecular technologies for identifying the risk of second cancers. Cancer Prev Res (Phila). 2009 Jul; 2(7):605-7. PMID: 19584072; PMCID: PMC2733247.
      115. Rothberg AE, Raymond VM, Gruber S, Sisson J. Familial medullary thyroid carcinoma associated with cutaneous lichen amyloidosis. Thyroid. 2009 Jun; 19(6):651-5. PMID: 19445625.
        View in: PubMed
      116. Marvin ML, Bradford CR, Sisson JC, Gruber S. Diagnosis and management of hereditary paraganglioma syndrome due to the F933>X67 SDHD mutation. Head Neck. 2009 May; 31(5):689-94. PMID: 19072999; PMCID: PMC4758329.
      117. Vilar E, Mukherjee B, Kuick R, Raskin L, Misek DE, Taylor JM, Giordano TJ, Hanash SM, Fearon ER, Rennert G, Gruber S. Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. Clin Cancer Res. 2009 Apr 15; 15(8):2829-39. PMID: 19351759; PMCID: PMC3425357.
      118. Raskin L, Rennert G, Gruber S. FOXP3 germline polymorphisms are not associated with risk of breast cancer. Cancer Genet Cytogenet. 2009 Apr 01; 190(1):40-2. PMID: 19264232.
        View in: PubMed
      119. Duffy SA, Ronis DL, McLean S, Fowler KE, Gruber S, Wolf GT, Terrell JE. Pretreatment health behaviors predict survival among patients with head and neck squamous cell carcinoma. J Clin Oncol. 2009 Apr 20; 27(12):1969-75. PMID: 19289626; PMCID: PMC2669762.
      120. Greenson JK, Huang SC, Herron C, Moreno V, Bonner JD, Tomsho LP, Ben-Izhak O, Cohen HI, Trougouboff P, Bejhar J, Sova Y, Pinchev M, Rennert G, Gruber S. Pathologic predictors of microsatellite instability in colorectal cancer. Am J Surg Pathol. 2009 Jan; 33(1):126-33. PMID: 18830122; PMCID: PMC3500028.
      121. Gruber S, Mukherjee B. Anticipation in lynch syndrome: still waiting for the answer. J Clin Oncol. 2009 Jan 20; 27(3):326-7. PMID: 19075261.
        View in: PubMed
      122. Khoury-Shakour S, Gruber S, Lejbkowicz F, Rennert HS, Raskin L, Pinchev M, Rennert G. Recreational physical activity modifies the association between a common GH1 polymorphism and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev. 2008 Dec; 17(12):3314-8. PMID: 19064544; PMCID: PMC2665206.
      123. Mukherjee B, Ahn J, Gruber S, Rennert G, Moreno V, Chatterjee N. Tests for gene-environment interaction from case-control data: a novel study of type I error, power and designs. Genet Epidemiol. 2008 Nov; 32(7):615-26. PMID: 18473390.
        View in: PubMed
      124. Polydorides AD, Mukherjee B, Gruber S, McKenna BJ, Appelman HD, Greenson JK. Adenoma-infiltrating lymphocytes (AILs) are a potential marker of hereditary nonpolyposis colorectal cancer. Am J Surg Pathol. 2008 Nov; 32(11):1661-6. PMID: 18753941; PMCID: PMC3500084.
      125. Toland AE, Rozek LS, Presswala S, Rennert G, Gruber S. PTPRJ haplotypes and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev. 2008 Oct; 17(10):2782-5. PMID: 18843023.
        View in: PubMed
      126. Lavie O, Gruber S, Lejbkowicz F, Dishon S, Rennert G. Gynecologic malignancies in Ashkenazi families with the MSH2 A636P founder mutation. Am J Obstet Gynecol. 2008 Aug; 199(2):148.e1-3. PMID: 18674656.
        View in: PubMed
      127. Zhang L, Mukherjee B, Ghosh M, Gruber S, Moreno V. Accounting for error due to misclassification of exposures in case-control studies of gene-environment interaction. Stat Med. 2008 Jul 10; 27(15):2756-83. PMID: 17879261.
        View in: PubMed
      128. Chao EC, Velasquez JL, Witherspoon MS, Rozek LS, Peel D, Ng P, Gruber S, Watson P, Rennert G, Anton-Culver H, Lynch H, Lipkin SM. Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR). Hum Mutat. 2008 Jun; 29(6):852-60. PMID: 18383312.
        View in: PubMed
      129. Karvonen-Gutierrez CA, Ronis DL, Fowler KE, Terrell JE, Gruber S, Duffy SA. Quality of life scores predict survival among patients with head and neck cancer. J Clin Oncol. 2008 Jun 01; 26(16):2754-60. PMID: 18509185.
        View in: PubMed
      130. Ahvenainen T, Lehtonen HJ, Lehtonen R, Vahteristo P, Aittomäki K, Baynam G, Dommering C, Eng C, Gruber S, Grönberg H, Harvima R, Herva R, Hietala M, Kujala M, Kääriäinen H, Sunde L, Vierimaa O, Pollard PJ, Tomlinson IP, Björck E, Aaltonen LA, Launonen V. Mutation screening of fumarate hydratase by multiplex ligation-dependent probe amplification: detection of exonic deletion in a patient with leiomyomatosis and renal cell cancer. Cancer Genet Cytogenet. 2008 Jun; 183(2):83-8. PMID: 18503824.
        View in: PubMed
      131. Sinha S, Gruber S, Mukherjee B, Rennert G. Inference of the haplotype effect in a matched case-control study using unphased genotype data. Int J Biostat. 2008 May 08; 4(1):Article 6. PMID: 20231916.
        View in: PubMed
      132. Raskin L, Pinchev M, Arad C, Lejbkowicz F, Tamir A, Rennert HS, Rennert G, Gruber S. FGFR2 is a breast cancer susceptibility gene in Jewish and Arab Israeli populations. Cancer Epidemiol Biomarkers Prev. 2008 May; 17(5):1060-5. PMID: 18483326.
        View in: PubMed
      133. Hensley Alford S, Schwartz K, Soliman A, Johnson CC, Gruber S, Merajver SD. Breast cancer characteristics at diagnosis and survival among Arab-American women compared to European- and African-American women. Breast Cancer Res Treat. 2009 Mar; 114(2):339-46. PMID: 18415013; PMCID: PMC2804102.
      134. Tenesa A, Farrington SM, Prendergast JG, Porteous ME, Walker M, Haq N, Barnetson RA, Theodoratou E, Cetnarskyj R, Cartwright N, Semple C, Clark AJ, Reid FJ, Smith LA, Kavoussanakis K, Koessler T, Pharoah PD, Buch S, Schafmayer C, Tepel J, Schreiber S, Völzke H, Schmidt CO, Hampe J, Chang-Claude J, Hoffmeister M, Brenner H, Wilkening S, Canzian F, Capella G, Moreno V, Deary IJ, Starr JM, Tomlinson IP, Kemp Z, Howarth K, Carvajal-Carmona L, Webb E, Broderick P, Vijayakrishnan J, Houlston RS, Rennert G, Ballinger D, Rozek L, Gruber S, Matsuda K, Kidokoro T, Nakamura Y, Zanke BW, Greenwood CM, Rangrej J, Kustra R, Montpetit A, Hudson TJ, Gallinger S, Campbell H, Dunlop MG. Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet. 2008 May; 40(5):631-7. PMID: 18372901; PMCID: PMC2778004.
      135. Stoffel EM, Ford B, Mercado RC, Punglia D, Kohlmann W, Conrad P, Blanco A, Shannon KM, Powell M, Gruber S, Terdiman J, Chung DC, Syngal S. Sharing genetic test results in Lynch syndrome: communication with close and distant relatives. Clin Gastroenterol Hepatol. 2008 Mar; 6(3):333-8. PMID: 18258490; PMCID: PMC2536607.
      136. Solé X, Hernández P, de Heredia ML, Armengol L, Rodríguez-Santiago B, Gómez L, Maxwell CA, Aguiló F, Condom E, Abril J, Pérez-Jurado L, Estivill X, Nunes V, Capellá G, Gruber S, Moreno V, Pujana MA. Genetic and genomic analysis modeling of germline c-MYC overexpression and cancer susceptibility. BMC Genomics. 2008 Jan 11; 9:12. PMID: 18190704; PMCID: PMC2244606.
      137. Sisson JC, Giordano TJ, Raymond VM, Doherty GM, Gruber S. First description of parathyroid disease in multiple endocrine neoplasia 2A syndrome. Endocr Pathol. 2008; 19(4):289-93. PMID: 19034701; PMCID: PMC2676676.
      138. Duffy SA, Khan MJ, Ronis DL, Fowler KE, Gruber S, Wolf GT, Terrell JE. Health behaviors of head and neck cancer patients the first year after diagnosis. Head Neck. 2008 Jan; 30(1):93-102. PMID: 17685451.
        View in: PubMed
      139. Chaiter Y, Rennert G, Fischler R, Rennert HS, Rozen G, Gruber S, Amotz AB. Dietary intake of carotenoid isomers in Israel. Int J Vitam Nutr Res. 2007 Nov; 77(6):398-405. PMID: 18622950.
        View in: PubMed
      140. Pujana MA, Han JD, Starita LM, Stevens KN, Tewari M, Ahn JS, Rennert G, Moreno V, Kirchhoff T, Gold B, Assmann V, Elshamy WM, Rual JF, Levine D, Rozek LS, Gelman RS, Gunsalus KC, Greenberg RA, Sobhian B, Bertin N, Venkatesan K, Ayivi-Guedehoussou N, Solé X, Hernández P, Lázaro C, Nathanson KL, Weber BL, Cusick ME, Hill DE, Offit K, Livingston DM, Gruber S, Parvin JD, Vidal M. Network modeling links breast cancer susceptibility and centrosome dysfunction. Nat Genet. 2007 Nov; 39(11):1338-49. PMID: 17922014.
        View in: PubMed
      141. Gruber S, Moreno V, Rozek LS, Rennerts HS, Lejbkowicz F, Bonner JD, Greenson JK, Giordano TJ, Fearson ER, Rennert G. Genetic variation in 8q24 associated with risk of colorectal cancer. Cancer Biol Ther. 2007 Jul; 6(7):1143-7. PMID: 17630503.
        View in: PubMed
      142. Kangelaris KN, Gruber S. Clinical implications of founder and recurrent CDH1 mutations in hereditary diffuse gastric cancer. JAMA. 2007 Jun 06; 297(21):2410-1. PMID: 17545691.
        View in: PubMed
      143. Orlow I, Begg CB, Cotignola J, Roy P, Hummer AJ, Clas BA, Mujumdar U, Canchola R, Armstrong BK, Kricker A, Marrett LD, Millikan RC, Gruber S, Anton-Culver H, Zanetti R, Gallagher RP, Dwyer T, Rebbeck TR, Kanetsky PA, Wilcox H, Busam K, From L, Berwick M. CDKN2A germline mutations in individuals with cutaneous malignant melanoma. J Invest Dermatol. 2007 May; 127(5):1234-43. PMID: 17218939.
        View in: PubMed
      144. Gruber S. Population stratification in epidemiologic studies of founder populations. Cancer Biomark. 2007; 3(3):123-8. PMID: 17611302.
        View in: PubMed
      145. Winchester JF, Harbord N, Audia P, Dubrow A, Gruber S, Feinfeld D, Amerling R. The 2006 K/DOQI guidelines for peritoneal dialysis adequacy are not adequate. Blood Purif. 2007; 25(1):103-5. PMID: 17170545.
        View in: PubMed
      146. Rozek LS, Rennert G, Gruber S. APC E1317Q is not associated with Colorectal Cancer in a population-based case-control study in Northern Israel. Cancer Epidemiol Biomarkers Prev. 2006 Nov; 15(11):2325-7. PMID: 17119068.
        View in: PubMed
      147. Guillem JG, Wood WC, Moley JF, Berchuck A, Karlan BY, Mutch DG, Gagel RF, Weitzel J, Morrow M, Weber BL, Giardiello F, Rodriguez-Bigas MA, Church J, Gruber S, Offit K. ASCO/SSO review of current role of risk-reducing surgery in common hereditary cancer syndromes. J Clin Oncol. 2006 Oct 01; 24(28):4642-60. PMID: 17008706.
        View in: PubMed
      148. Guillem JG, Wood WC, Moley JF, Berchuck A, Karlan BY, Mutch DG, Gagel RF, Weitzel J, Morrow M, Weber BL, Giardiello F, Rodriguez-Bigas MA, Church J, Gruber S, Offit K. ASCO/SSO review of current role of risk-reducing surgery in common hereditary cancer syndromes. Ann Surg Oncol. 2006 Oct; 13(10):1296-321. PMID: 16990987.
        View in: PubMed
      149. Chen S, Wang W, Lee S, Nafa K, Lee J, Romans K, Watson P, Gruber S, Euhus D, Kinzler KW, Jass J, Gallinger S, Lindor NM, Casey G, Ellis N, Giardiello FM, Offit K, Parmigiani G. Prediction of germline mutations and cancer risk in the Lynch syndrome. JAMA. 2006 Sep 27; 296(12):1479-87. PMID: 17003396; PMCID: PMC2538673.
      150. Kanetsky PA, Rebbeck TR, Hummer AJ, Panossian S, Armstrong BK, Kricker A, Marrett LD, Millikan RC, Gruber S, Culver HA, Zanetti R, Gallagher RP, Dwyer T, Busam K, From L, Mujumdar U, Wilcox H, Begg CB, Berwick M. Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma. Cancer Res. 2006 Sep 15; 66(18):9330-7. PMID: 16982779.
        View in: PubMed
      151. Denoyelle C, Abou-Rjaily G, Bezrookove V, Verhaegen M, Johnson TM, Fullen DR, Pointer JN, Gruber S, Su LD, Nikiforov MA, Kaufman RJ, Bastian BC, Soengas MS. Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway. Nat Cell Biol. 2006 Oct; 8(10):1053-63. PMID: 16964246.
        View in: PubMed
      152. Miller DC, Gruber S, Hollenbeck BK, Montie JE, Wei JT. Incidence of initial local therapy among men with lower-risk prostate cancer in the United States. J Natl Cancer Inst. 2006 Aug 16; 98(16):1134-41. PMID: 16912266.
        View in: PubMed
      153. Berwick M, Orlow I, Hummer AJ, Armstrong BK, Kricker A, Marrett LD, Millikan RC, Gruber S, Anton-Culver H, Zanetti R, Gallagher RP, Dwyer T, Rebbeck TR, Kanetsky PA, Busam K, From L, Mujumdar U, Wilcox H, Begg CB. The prevalence of CDKN2A germ-line mutations and relative risk for cutaneous malignant melanoma: an international population-based study. Cancer Epidemiol Biomarkers Prev. 2006 Aug; 15(8):1520-5. PMID: 16896043.
        View in: PubMed
      154. Poynter JN, Elder JT, Fullen DR, Nair RP, Soengas MS, Johnson TM, Redman B, Thomas NE, Gruber S. BRAF and NRAS mutations in melanoma and melanocytic nevi. Melanoma Res. 2006 Aug; 16(4):267-73. PMID: 16845322.
        View in: PubMed
      155. Gruber PJ, Fuller S, Cleaver KM, Abdullah I, Gruber S, Nicolson SC, Gaynor JW, Wernovsky G, Spray TL. Early results of single-stage biventricular repair of severe aortic hypoplasia or atresia with ventricular septal defect and normal left ventricle. J Thorac Cardiovasc Surg. 2006 Aug; 132(2):260-3. PMID: 16872947.
        View in: PubMed
      156. Fullen DR, Poynter JN, Lowe L, Su LD, Elder JT, Nair RP, Johnson TM, Gruber S. BRAF and NRAS mutations in spitzoid melanocytic lesions. Mod Pathol. 2006 Oct; 19(10):1324-32. PMID: 16799476.
        View in: PubMed
      157. Hearle N, Schumacher V, Menko FH, Olschwang S, Boardman LA, Gille JJ, Keller JJ, Westerman AM, Scott RJ, Lim W, Trimbath JD, Giardiello FM, Gruber S, Offerhaus GJ, de Rooij FW, Wilson JH, Hansmann A, Möslein G, Royer-Pokora B, Vogel T, Phillips RK, Spigelman AD, Houlston RS. Frequency and spectrum of cancers in the Peutz-Jeghers syndrome. Clin Cancer Res. 2006 May 15; 12(10):3209-15. PMID: 16707622.
        View in: PubMed
      158. Lin L, Wang Z, Prescott MS, van Dekken H, Thomas DG, Giordano TJ, Chang AC, Orringer MB, Gruber S, Moran JV, Glover TW, Beer DG. Multiple forms of genetic instability within a 2-Mb chromosomal segment of 3q26.3-q27 are associated with development of esophageal adenocarcinoma. Genes Chromosomes Cancer. 2006 Apr; 45(4):319-31. PMID: 16320248.
        View in: PubMed
      159. Levin B, Barthel JS, Burt RW, David DS, Ford JM, Giardiello FM, Gruber S, Halverson AL, Hamilton S, Kohlmann W, Ludwig KA, Lynch PM, Marino C, Martin EW, Mayer RJ, Pasche B, Pirruccello SJ, Rajput A, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D, Winawer SJ. Colorectal Cancer Screening Clinical Practice Guidelines. J Natl Compr Canc Netw. 2006 Apr; 4(4):384-420. PMID: 16569391.
        View in: PubMed
      160. Begg CB, Hummer AJ, Mujumdar U, Armstrong BK, Kricker A, Marrett LD, Millikan RC, Gruber S, Culver HA, Zanetti R, Gallagher RP, Dwyer T, Rebbeck TR, Busam K, From L, Berwick M. A design for cancer case-control studies using only incident cases: experience with the GEM study of melanoma. Int J Epidemiol. 2006 Jun; 35(3):756-64. PMID: 16556646.
        View in: PubMed
      161. Jeter JM, Kohlmann W, Gruber S. Genetics of colorectal cancer. Oncology (Williston Park). 2006 Mar; 20(3):269-76; discussion 285-6, 288-9. PMID: 16629258.
        View in: PubMed
      162. Poynter JN, Cooney KA, Bonner JD, White KA, Tomsho LP, Rennert G, Gruber S. APC I1307K and the risk of prostate cancer. Cancer Epidemiol Biomarkers Prev. 2006 Mar; 15(3):468-73. PMID: 16537703.
        View in: PubMed
      163. Rosamilia LL, Schwartz JL, Lowe L, Gruber S, Quint EH, Johnson TM, Reynolds RK, Haefner HK. Vulvar melanoma in a 10-year-old girl in association with lichen sclerosus. J Am Acad Dermatol. 2006 Feb; 54(2 Suppl):S52-3. PMID: 16427997.
        View in: PubMed
      164. Gruber S. New developments in Lynch syndrome (hereditary nonpolyposis colorectal cancer) and mismatch repair gene testing. Gastroenterology. 2006 Feb; 130(2):577-87. PMID: 16472609.
        View in: PubMed
      165. Demierre MF, Higgins PD, Gruber S, Hawk E, Lippman SM. Statins and cancer prevention. Nat Rev Cancer. 2005 Dec; 5(12):930-42. PMID: 16341084.
        View in: PubMed
      166. Rennert G, Almog R, Tomsho LP, Low M, Pinchev M, Chaiter Y, Bonner JD, Rennert HS, Greenson JK, Gruber S. Colorectal polyps in carriers of the APC I1307K polymorphism. Dis Colon Rectum. 2005 Dec; 48(12):2317-21. PMID: 16228836.
        View in: PubMed
      167. Douglas JA, Gruber S, Meister KA, Bonner J, Watson P, Krush AJ, Lynch HT. History and molecular genetics of Lynch syndrome in family G: a century later. JAMA. 2005 Nov 02; 294(17):2195-202. PMID: 16264161.
        View in: PubMed
      168. Gruber S. The value of small observations in the era of big science. Cancer Epidemiol Biomarkers Prev. 2005 Nov; 14(11 Pt 1):2472-3. PMID: 16284365.
        View in: PubMed
      169. Millikan RC, Hummer A, Begg C, Player J, de Cotret AR, Winkel S, Mohrenweiser H, Thomas N, Armstrong B, Kricker A, Marrett LD, Gruber S, Culver HA, Zanetti R, Gallagher RP, Dwyer T, Rebbeck TR, Busam K, From L, Mujumdar U, Berwick M. Polymorphisms in nucleotide excision repair genes and risk of multiple primary melanoma: the Genes Environment and Melanoma Study. Carcinogenesis. 2006 Mar; 27(3):610-8. PMID: 16258177.
        View in: PubMed
      170. Begg CB, Orlow I, Hummer AJ, Armstrong BK, Kricker A, Marrett LD, Millikan RC, Gruber S, Anton-Culver H, Zanetti R, Gallagher RP, Dwyer T, Rebbeck TR, Mitra N, Busam K, From L, Berwick M. Lifetime risk of melanoma in CDKN2A mutation carriers in a population-based sample. J Natl Cancer Inst. 2005 Oct 19; 97(20):1507-15. PMID: 16234564.
        View in: PubMed
      171. Shin BY, Chen H, Rozek LS, Paxton L, Peel DJ, Anton-Culver H, Rennert G, Mutch DG, Goodfellow PJ, Gruber S, Lipkin SM. Low allele frequency of MLH1 D132H in American colorectal and endometrial cancer patients. Dis Colon Rectum. 2005 Sep; 48(9):1723-7. PMID: 15991064.
        View in: PubMed
      172. Douglas JA, Zuhlke KA, Beebe-Dimmer J, Levin AM, Gruber S, Wood DP, Cooney KA. Identifying susceptibility genes for prostate cancer--a family-based association study of polymorphisms in CYP17, CYP19, CYP11A1, and LH-beta. Cancer Epidemiol Biomarkers Prev. 2005 Aug; 14(8):2035-9. PMID: 16103457.
        View in: PubMed
      173. Rozek LS, Lipkin SM, Fearon ER, Hanash S, Giordano TJ, Greenson JK, Kuick R, Misek DE, Taylor JM, Douglas JA, Rennert G, Gruber S. CDX2 polymorphisms, RNA expression, and risk of colorectal cancer. Cancer Res. 2005 Jul 01; 65(13):5488-92. PMID: 15994917.
        View in: PubMed
      174. Poynter JN, Gruber S, Higgins PD, Almog R, Bonner JD, Rennert HS, Low M, Greenson JK, Rennert G. Statins and the risk of colorectal cancer. N Engl J Med. 2005 May 26; 352(21):2184-92. PMID: 15917383.
        View in: PubMed
      175. Hinoi T, Gesina G, Akyol A, Kuick R, Hanash S, Giordano TJ, Gruber S, Fearon ER. CDX2-regulated expression of iron transport protein hephaestin in intestinal and colonic epithelium. Gastroenterology. 2005 Apr; 128(4):946-61. PMID: 15825077.
        View in: PubMed
      176. Shedden K, Chen W, Kuick R, Ghosh D, Macdonald J, Cho KR, Giordano TJ, Gruber S, Fearon ER, Taylor JM, Hanash S. Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data. BMC Bioinformatics. 2005 Feb 10; 6:26. PMID: 15705192; PMCID: PMC550659.
      177. Cooney KA, Gruber S. Hyperglycemia, obesity, and cancer risks on the horizon. JAMA. 2005 Jan 12; 293(2):235-6. PMID: 15644552.
        View in: PubMed
      178. Madison T, Schottenfeld D, James SA, Schwartz AG, Gruber S. Endometrial cancer: socioeconomic status and racial/ethnic differences in stage at diagnosis, treatment, and survival. Am J Public Health. 2004 Dec; 94(12):2104-11. PMID: 15569961; PMCID: PMC1448599.
      179. Begg CB, Hummer A, Mujumdar U, Armstrong BK, Kricker A, Marrett LD, Millikan RC, Gruber S, Anton-Culver H, Klotz JB, Zanetti R, Gallagher RP, Dwyer T, Rebbeck TR, Berwick M. Familial aggregation of melanoma risks in a large population-based sample of melanoma cases. Cancer Causes Control. 2004 Nov; 15(9):957-65. PMID: 15577298.
        View in: PubMed
      180. Zuhlke KA, Madeoy JJ, Beebe-Dimmer J, White KA, Griffin A, Lange EM, Gruber S, Ostrander EA, Cooney KA. Truncating BRCA1 mutations are uncommon in a cohort of hereditary prostate cancer families with evidence of linkage to 17q markers. Clin Cancer Res. 2004 Sep 15; 10(18 Pt 1):5975-80. PMID: 15447980.
        View in: PubMed
      181. Lipkin SM, Rozek LS, Rennert G, Yang W, Chen PC, Hacia J, Hunt N, Shin B, Fodor S, Kokoris M, Greenson JK, Fearon E, Lynch H, Collins F, Gruber S. The MLH1 D132H variant is associated with susceptibility to sporadic colorectal cancer. Nat Genet. 2004 Jul; 36(7):694-9. PMID: 15184898.
        View in: PubMed
      182. Lim W, Olschwang S, Keller JJ, Westerman AM, Menko FH, Boardman LA, Scott RJ, Trimbath J, Giardiello FM, Gruber S, Gille JJ, Offerhaus GJ, de Rooij FW, Wilson JH, Spigelman AD, Phillips RK, Houlston RS. Relative frequency and morphology of cancers in STK11 mutation carriers. Gastroenterology. 2004 Jun; 126(7):1788-94. PMID: 15188174.
        View in: PubMed
      183. Amend KL, Elder JT, Tomsho LP, Bonner JD, Johnson TM, Schwartz J, Berwick M, Gruber S. EGF gene polymorphism and the risk of incident primary melanoma. Cancer Res. 2004 Apr 15; 64(8):2668-72. PMID: 15087376.
        View in: PubMed
      184. Beebe-Dimmer JL, Wood DP, Gruber S, Chilson DM, Zuhlke KA, Claeys GB, Cooney KA. Risk perception and concern among brothers of men with prostate carcinoma. Cancer. 2004 Apr 01; 100(7):1537-44. PMID: 15042690.
        View in: PubMed
      185. Wechter ME, Gruber S, Haefner HK, Lowe L, Schwartz JL, Reynolds KR, Johnston CM, Johnson TM. Vulvar melanoma: a report of 20 cases and review of the literature. J Am Acad Dermatol. 2004 Apr; 50(4):554-62. PMID: 15034504.
        View in: PubMed
      186. Wilson LD, Gruber S. Merkel cell carcinoma and the controversial role of adjuvant radiation therapy: clinical choices in the absence of statistical evidence. J Am Acad Dermatol. 2004 Mar; 50(3):435-7; discussion 437-8. PMID: 14988686.
        View in: PubMed
      187. Beebe-Dimmer JL, Wood DP, Gruber S, Douglas JA, Bonner JD, Mohai C, Zuhlke KA, Shepherd C, Cooney KA. Use of complementary and alternative medicine in men with family history of prostate cancer: a pilot study. Urology. 2004 Feb; 63(2):282-7. PMID: 14972472.
        View in: PubMed
      188. Niell BL, Rennert G, Bonner JD, Almog R, Tomsho LP, Gruber S. BRCA1 and BRCA2 founder mutations and the risk of colorectal cancer. J Natl Cancer Inst. 2004 Jan 07; 96(1):15-21. PMID: 14709734.
        View in: PubMed
      189. Johnson TM, Bradford CR, Gruber S, Sondak VK, Schwartz JL. Staging workup, sentinel node biopsy, and follow-up tests for melanoma: update of current concepts. Arch Dermatol. 2004 Jan; 140(1):107-13. PMID: 14732667.
        View in: PubMed
      190. Wechter ME, Reynolds RK, Haefner HK, Lowe L, Gruber S, Schwartz JL, Johnston CM, Johnson TM. Vulvar melanoma: review of diagnosis, staging, and therapy. J Low Genit Tract Dis. 2004 Jan; 8(1):58-69. PMID: 15874838.
        View in: PubMed
      191. Niell BL, Long JC, Rennert G, Gruber S. Genetic anthropology of the colorectal cancer-susceptibility allele APC I1307K: evidence of genetic drift within the Ashkenazim. Am J Hum Genet. 2003 Dec; 73(6):1250-60. PMID: 14624392; PMCID: PMC1180391.
      192. Shedden KA, Taylor JM, Giordano TJ, Kuick R, Misek DE, Rennert G, Schwartz DR, Gruber S, Logsdon C, Simeone D, Kardia SL, Greenson JK, Cho KR, Beer DG, Fearon ER, Hanash S. Accurate molecular classification of human cancers based on gene expression using a simple classifier with a pathological tree-based framework. Am J Pathol. 2003 Nov; 163(5):1985-95. PMID: 14578198; PMCID: PMC1892445.
      193. Bock CH, Peyser PA, Gruber S, Bonnell SE, Tedesco KL, Cooney KA. Prostate cancer early detection practices among men with a family history of disease. Urology. 2003 Sep; 62(3):470-5. PMID: 12946749.
        View in: PubMed
      194. De Leng WW, Westerman AM, Weterman MA, De Rooij FW, Dekken Hv Hv, De Goeij AF, Gruber S, Wilson JH, Offerhaus GJ, Giardiello FM, Keller JJ. Cyclooxygenase 2 expression and molecular alterations in Peutz-Jeghers hamartomas and carcinomas. Clin Cancer Res. 2003 Aug 01; 9(8):3065-72. PMID: 12912958.
        View in: PubMed
      195. Greenson JK, Bonner JD, Ben-Yzhak O, Cohen HI, Miselevich I, Resnick MB, Trougouboff P, Tomsho LD, Kim E, Low M, Almog R, Rennert G, Gruber S. Phenotype of microsatellite unstable colorectal carcinomas: Well-differentiated and focally mucinous tumors and the absence of dirty necrosis correlate with microsatellite instability. Am J Surg Pathol. 2003 May; 27(5):563-70. PMID: 12717242.
        View in: PubMed
      196. Gruber S, Chen H, Tomsho LP, Lee N, Perrone EE, Cooney KA. R726L androgen receptor mutation is uncommon in prostate cancer families in the united states. Prostate. 2003 Mar 01; 54(4):306-9. PMID: 12539229.
        View in: PubMed
      197. Gruber S, Kohlmann W. The genetics of hereditary non-polyposis colorectal cancer. J Natl Compr Canc Netw. 2003 Jan; 1(1):137-44. PMID: 19764157.
        View in: PubMed
      198. Gruber S, Ellis NA, Scott KK, Almog R, Kolachana P, Bonner JD, Kirchhoff T, Tomsho LP, Nafa K, Pierce H, Low M, Satagopan J, Rennert H, Huang H, Greenson JK, Groden J, Rapaport B, Shia J, Johnson S, Gregersen PK, Harris CC, Boyd J, Rennert G, Offit K. BLM heterozygosity and the risk of colorectal cancer. Science. 2002 Sep 20; 297(5589):2013. PMID: 12242432.
        View in: PubMed
      199. Gruber S, Petersen GM. Cancer risks in BRCA1 carriers: time for the next generation of studies. J Natl Cancer Inst. 2002 Sep 18; 94(18):1344-5. PMID: 12237273.
        View in: PubMed
      200. Yan H, Dobbie Z, Gruber S, Markowitz S, Romans K, Giardiello FM, Kinzler KW, Vogelstein B. Small changes in expression affect predisposition to tumorigenesis. Nat Genet. 2002 Jan; 30(1):25-6. PMID: 11743581.
        View in: PubMed