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    Nyam-Osor Chimge, PhD

    TitleAssistant Professor of Research Medicine
    SchoolKeck School of Medicine of USC
    AddressHMR 911A
    Health Sciences Campus
    Los Angeles California 90033
    Phone+1 323 442 3914
    vCardDownload vCard

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Chimge N, Ahmed-Alnassar S, Frenkel B. Relationship between RUNX1 and AXIN1 in ER-negative versus ER-positive Breast Cancer. Cell Cycle. 2017 Feb 16; 16(4):312-318. PMID: 28055379.
        View in: PubMed
      2. Yang Y, He S, Wang Q, Li F, Kwak MJ, Chen S, O'Connell D, Zhang T, Pirooz SD, Jeon Y, Chimge N, Frenkel B, Choi Y, Aldrovandi GM, Oh BH, Yuan Z, Liang C. Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase. Mol Cell. 2016 May 19; 62(4):507-19. PMID: 27203177; PMCID: PMC4875571 [Available on 05/19/17].
      3. Morimoto E, Li M, Khalid AB, Krum SA, Chimge N, Frenkel B. Glucocorticoids Hijack Runx2 to Stimulate Wif1 for Suppression of Osteoblast Growth and Differentiation. J Cell Physiol. 2017 Jan; 232(1):145-53. PMID: 27061521.
        View in: PubMed
      4. Chimge N, Little GH, Baniwal SK, Adisetiyo H, Xie Y, Zhang T, O'Laughlin A, Liu ZY, Ulrich P, Martin A, Mhawech-Fauceglia P, Ellis MJ, Tripathy D, Groshen S, Liang C, Li Z, Schones DE, Frenkel B. RUNX1 prevents oestrogen-mediated AXIN1 suppression and ß-catenin activation in ER-positive breast cancer. Nat Commun. 2016 Feb 26; 7:10751. PMID: 26916619; PMCID: PMC4773428.
      5. Martin A, Xiong J, Koromila T, Ji JS, Chang S, Song YS, Miller JL, Han CY, Kostenuik P, Krum SA, Chimge N, Gabet Y, Frenkel B. Estrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association. Bone. 2015 Jun; 75:96-104. PMID: 25701138; PMCID: PMC4387095.
      6. Little GH, Baniwal SK, Adisetiyo H, Groshen S, Chimge N, Kim SY, Khalid O, Hawes D, Jones JO, Pinski J, Schones DE, Frenkel B. Differential effects of RUNX2 on the androgen receptor in prostate cancer: synergistic stimulation of a gene set exemplified by SNAI2 and subsequent invasiveness. Cancer Res. 2014 May 15; 74(10):2857-68. PMID: 24648349; PMCID: PMC4051204.
      7. Baniwal SK, Chimge N, Jordan VC, Tripathy D, Frenkel B. Prolactin-induced protein (PIP) regulates proliferation of luminal A type breast cancer cells in an estrogen-independent manner. PLoS One. 2014; 8(6):e62361. PMID: 23755096; PMCID: PMC3670933.
      8. Chimge N, Frenkel B. The RUNX family in breast cancer: relationships with estrogen signaling. Oncogene. 2013 Apr 25; 32(17):2121-30. PMID: 23045283.
        View in: PubMed
      9. Baniwal SK, Little GH, Chimge N, Frenkel B. Runx2 controls a feed-forward loop between androgen and prolactin-induced protein (PIP) in stimulating T47D cell proliferation. J Cell Physiol. 2012 May; 227(5):2276-82. PMID: 21809344; PMCID: PMC3376385.
      10. Chimge N, Makeyev AV, Waigel SJ, Enkhmandakh B, Bayarsaihan D. PI3K/Akt-dependent functions of TFII-I transcription factors in mouse embryonic stem cells. J Cell Biochem. 2012 Apr; 113(4):1122-31. PMID: 22274952.
        View in: PubMed
      11. Chimge N, Baniwal SK, Little GH, Chen YB, Kahn M, Tripathy D, Borok Z, Frenkel B. Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2. Breast Cancer Res. 2011; 13(6):R127. PMID: 22151997; PMCID: PMC3326569.
      12. Chimge N, Baniwal SK, Luo J, Coetzee S, Khalid O, Berman BP, Tripathy D, Ellis MJ, Frenkel B. Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness. Clin Cancer Res. 2012 Feb 01; 18(3):901-11. PMID: 22147940; PMCID: PMC3277803.
      13. Pramanik S, Cui X, Wang HY, Chimge N, Hu G, Shen L, Gao R, Li H. Segmental duplication as one of the driving forces underlying the diversity of the human immunoglobulin heavy chain variable gene region. BMC Genomics. 2011 Jan 27; 12:78. PMID: 21272357; PMCID: PMC3042411.
      14. Chimge N, Bayarsaihan D. Generation of neural crest progenitors from human embryonic stem cells. J Exp Zool B Mol Dev Evol. 2010 Mar 15; 314(2):95-103. PMID: 19780036.
        View in: PubMed
      15. Enkhmandakh B, Makeyev AV, Erdenechimeg L, Ruddle FH, Chimge N, Tussie-Luna MI, Roy AL, Bayarsaihan D. Essential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic development. Proc Natl Acad Sci U S A. 2009 Jan 06; 106(1):181-6. PMID: 19109438; PMCID: PMC2629217.
      16. Chimge N, Makeyev AV, Ruddle FH, Bayarsaihan D. Identification of the TFII-I family target genes in the vertebrate genome. Proc Natl Acad Sci U S A. 2008 Jul 01; 105(26):9006-10. PMID: 18579769; PMCID: PMC2449355.
      17. Hirayasu K, Ohashi J, Tanaka H, Kashiwase K, Ogawa A, Takanashi M, Satake M, Jia GJ, Chimge N, Sideltseva EW, Tokunaga K, Yabe T. Evidence for natural selection on leukocyte immunoglobulin-like receptors for HLA class I in Northeast Asians. Am J Hum Genet. 2008 May; 82(5):1075-83. PMID: 18439545; PMCID: PMC2427302.
      18. Chimge N, Mungunsukh O, Ruddle F, Bayarsaihan D. Expression profiling of BEN regulated genes in mouse embryonic fibroblasts. J Exp Zool B Mol Dev Evol. 2007 May 15; 308(3):209-24. PMID: 17041962.
        View in: PubMed
      19. Chimge N, Mungunsukh O, Ruddle F, Bayarsaihan D. Gene expression analysis of TFII-I modulated genes in mouse embryonic fibroblasts. J Exp Zool B Mol Dev Evol. 2007 May 15; 308(3):225-35. PMID: 17094079.
        View in: PubMed
      20. Chimge N, Ruddle F, Bayarsaihan D. Laser-assisted microdissection (LAM) in developmental biology. J Exp Zool B Mol Dev Evol. 2007 Mar 15; 308(2):113-8. PMID: 17016827.
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      21. Greenawalt DM, Cui X, Wu Y, Lin Y, Wang HY, Luo M, Tereshchenko IV, Hu G, Li JY, Chu Y, Azaro MA, Decoste CJ, Chimge N, Gao R, Shen L, Shih WJ, Lange K, Li H. Strong correlation between meiotic crossovers and haplotype structure in a 2.5-Mb region on the long arm of chromosome 21. Genome Res. 2006 Feb; 16(2):208-14. PMID: 16385099; PMCID: PMC1361716.
      22. Chimge N, Pramanik S, Hu G, Lin Y, Gao R, Shen L, Li H. Determination of gene organization in the human IGHV region on single chromosomes. Genes Immun. 2005 May; 6(3):186-93. PMID: 15744329.
        View in: PubMed
      23. Li H, Cui X, Pramanik S, Chimge N. Genetic diversity of the human immunoglobulin heavy chain VH region. Immunol Rev. 2002 Dec; 190:53-68. PMID: 12493006.
        View in: PubMed
      24. Komatsu-Wakui M, Tokunaga K, Ishikawa Y, Leelayuwat C, Kashiwase K, Tanaka H, Moriyama S, Nakajima F, Park MH, Jia GJ, Chimge N, Sideltseva EW, Juji T. Wide distribution of the MICA-MICB null haplotype in East Asians. Tissue Antigens. 2001 Jan; 57(1):1-8. PMID: 11169252.
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      25. Chimge N, Batsuuri J. Interethnic genetic differentiation: HLA class I antigens in the population of Mongolia. Am J Hum Biol. 1999 Sep; 11(5):603-618. PMID: 11533979.
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      26. Inoue T, Ogawa A, Tokunaga K, Ishikawa Y, Kashiwase K, Tanaka H, Park MH, Jia GJ, Chimge N, Sideltseva EW, Akaza T, Tadokoro K, Takahashi T, Juji T. Diversity of HLA-B17 alleles and haplotypes in East Asians and a novel Cw6 allele (Cw*0604) associated with B*5701. Tissue Antigens. 1999 Jun; 53(6):534-44. PMID: 10395103.
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      27. Ogawa A, Tokunaga K, Lin L, Kashiwase K, Tanaka H, Herrero MJ, Vilches C, Park MH, Jia GJ, Chimge N, Sideltseva EW, Ishikawa Y, Akaza T, Tadokoro K, Juji T. Diversity of HLA-B61 alleles and haplotypes in East Asians and Spanish Gypsies. Tissue Antigens. 1998 Apr; 51(4 Pt 1):356-66. PMID: 9583807.
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      28. Kashiwase K, Chimge N, Kawaga Y, Fujii M, Tanaka H, Tokunaga K, Akaza T, Batsuuri J, Juji T. A new HLA-DR14 allele, DRB1*1427, identified in the Mongolian population. Tissue Antigens. 1997 Dec; 50(6):682-4. PMID: 9458129.
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      29. Chimge N, Tanaka H, Kashiwase K, Ayush D, Tokunaga K, Saji H, Akaza T, Batsuuri J, Juji T. The HLA system in the population of Mongolia. Tissue Antigens. 1997 May; 49(5):477-83. PMID: 9174140.
        View in: PubMed