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    Junxiang Wan, MD, PhD

    TitleResearch Assistant Professor
    SchoolSchool of Gerontology
    DepartmentGerontology
    AddressGER 103
    University Park Campus
    Los Angeles California 90089-0191
    Phone+1 213 740 1354
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      Dr. Wan has extensive training in molecular biology, cell biology and immunology. She is an expert in the field of novel assay development, and has extensive experience in academic research work. Dr. Wan mastered novel ELISA assays for the entire murine IGF/IGFBP system and for human and murine humanin and have done lots of IGFs, IGFBPs and humanin assays with the other collaborators, and developed new assays for mitochondria small peptides (MDPs). She has directed core facilities at UCLA and USC, focusing on translation of assays and novel assay development.


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      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Kim SJ, Xiao J, Wan J, Cohen P, Yen K. Mitochondrially derived peptides as novel regulators of metabolism. J Physiol. 2017 Jun 02. PMID: 28574175.
        View in: PubMed
      2. Lue Y, Swerdloff R, Wan J, Xiao J, French S, Atienza V, Canela V, Bruhn KW, Stone B, Jia Y, Cohen P, Wang C. The Potent Humanin Analogue (HNG) Protects Germ Cells and Leucocytes While Enhancing Chemotherapy-Induced Suppression of Cancer Metastases in Male Mice. Endocrinology. 2015 Dec; 156(12):4511-21. PMID: 26384090; PMCID: PMC4655208 [Available on 12/01/16].
      3. Lee C, Zeng J, Drew BG, Sallam T, Martin-Montalvo A, Wan J, Kim SJ, Mehta H, Hevener AL, de Cabo R, Cohen P. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab. 2015 Mar 03; 21(3):443-54. PMID: 25738459; PMCID: PMC4350682.
      4. Lee C, Wan J, Miyazaki B, Fang Y, Guevara-Aguirre J, Yen K, Longo V, Bartke A, Cohen P. IGF-I regulates the age-dependent signaling peptide humanin. Aging Cell. 2014 Oct; 13(5):958-61. PMID: 25040290; PMCID: PMC4172517.
      5. Levine ME, Suarez JA, Brandhorst S, Balasubramanian P, Cheng CW, Madia F, Fontana L, Mirisola MG, Guevara-Aguirre J, Wan J, Passarino G, Kennedy BK, Wei M, Cohen P, Crimmins EM, Longo VD. Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. Cell Metab. 2014 Mar 04; 19(3):407-17. PMID: 24606898; PMCID: PMC3988204.
      6. Chin YP, Keni J, Wan J, Mehta H, Anene F, Jia Y, Lue YH, Swerdloff R, Cobb LJ, Wang C, Cohen P. Pharmacokinetics and tissue distribution of humanin and its analogues in male rodents. Endocrinology. 2013 Oct; 154(10):3739-44. PMID: 23836030; PMCID: PMC3776863.
      7. Parrella E, Maxim T, Maialetti F, Zhang L, Wan J, Wei M, Cohen P, Fontana L, Longo VD. Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model. Aging Cell. 2013 Apr; 12(2):257-68. PMID: 23362919; PMCID: PMC3982836.