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    John M. Ringman, MD, MS

    TitleProfessor of Clinical Neurology
    SchoolKeck School of Medicine of USC
    DepartmentNeurology
    AddressHCT 1520 San Pablo Street
    Health Sciences Campus
    Los Angeles California 90033-9405
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Grill JD, Cox CG, Kremen S, Mendez MF, Teng E, Shapira J, Ringman J, Apostolova LG. Patient and caregiver reactions to clinical amyloid imaging. Alzheimers Dement. 2017 Feb 04. PMID: 28174068.
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      2. Apostolova LG, Haider JM, Goukasian N, Rabinovici GD, Chételat G, Ringman J, Kremen S, Grill JD, Restrepo L, Mendez MF, Silverman DH. Critical review of the Appropriate Use Criteria for amyloid imaging: Effect on diagnosis and patient care. Alzheimers Dement (Amst). 2016; 5:15-22. PMID: 28054024.
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      3. Wilhalme H, Goukasian N, De Leon F, He A, Hwang KS, Woo E, Elashoff D, Zhou Y, Ringman J, Apostolova LG. A comparison of theoretical and statistically derived indices for predicting cognitive decline. Alzheimers Dement (Amst). 2017; 6:171-181. PMID: 28275699.
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      4. Tang M, Ryman DC, McDade E, Jasielec MS, Buckles VD, Cairns NJ, Fagan AM, Goate A, Marcus DS, Xiong C, Allegri RF, Chhatwal JP, Danek A, Farlow MR, Fox NC, Ghetti B, Graff-Radford NR, Laske C, Martins RN, Masters CL, Mayeux RP, Ringman J, Rossor MN, Salloway SP, Schofield PR, Morris JC, Bateman RJ. Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS). Lancet Neurol. 2016 Dec; 15(13):1317-1325. PMID: 27777020.
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      5. Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, McDade E, Ringman J, Thompson PM, Saykin AJ, Ghetti B, Sperling RA, Johnson KA, Salloway SP, Schofield PR, Masters CL, Villemagne VL, Fox NC, Förster S, Chen K, Reiman EM, Xiong C, Marcus DS, Weiner MW, Morris JC, Bateman RJ, Benzinger TL. Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. PLoS One. 2016; 11(9):e0163669. PMID: 27649320.
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      6. Ringman J. Are Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease "Separate but Equal"? JAMA Neurol. 2016 Sep 1; 73(9):1060-1. PMID: 27455517.
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      7. Lim YY, Hassenstab J, Cruchaga C, Goate A, Fagan AM, Benzinger TL, Maruff P, Snyder PJ, Masters CL, Allegri R, Chhatwal J, Farlow MR, Graff-Radford NR, Laske C, Levin J, McDade E, Ringman J, Rossor M, Salloway S, Schofield PR, Holtzman DM, Morris JC, Bateman RJ. BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease. Brain. 2016 Oct; 139(Pt 10):2766-2777. PMID: 27521573.
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      8. Soosman SK, Joseph-Mathurin N, Braskie MN, Bordelon YM, Wharton D, Casado M, Coppola G, McCallum H, Nuwer M, Coutin-Churchman P, Apostolova LG, Benzinger T, Ringman J. Widespread white matter and conduction defects in PSEN1-related spastic paraparesis. Neurobiol Aging. 2016 Nov; 47:201-209. PMID: 27614114.
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      9. Lee S, Viqar F, Zimmerman ME, Narkhede A, Tosto G, Benzinger TL, Marcus DS, Fagan AM, Goate A, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, Martins RN, Saykin AJ, Masters CL, Ringman J, Ryan NS, Förster S, Laske C, Schofield PR, Sperling RA, Salloway S, Correia S, Jack C, Weiner M, Bateman RJ, Morris JC, Mayeux R, Brickman AM. White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network. Ann Neurol. 2016 Jun; 79(6):929-39. PMID: 27016429.
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      10. Batalini F, Avidan A, Moseley BD, Ringman J. Improvement of Dream Enactment Behavior Associated With Levetiracetam Treatment in Dementia With Lewy Bodies. Alzheimer Dis Assoc Disord. 2016 Apr-Jun; 30(2):175-7. PMID: 26485499.
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      11. Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, McDade E, Ringman J, Thompson PM, Saykin AJ, Ghetti B, Sperling RA, Johnson KA, Salloway SP, Schofield PR, Masters CL, Villemagne VL, Fox NC, Förster S, Chen K, Reiman EM, Xiong C, Marcus DS, Weiner MW, Morris JC, Bateman RJ, Benzinger TL. Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. PLoS One. 2016; 11(3):e0152082. PMID: 27010959.
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      12. Ringman J, Monsell S, Ng DW, Zhou Y, Nguyen A, Coppola G, Van Berlo V, Mendez MF, Tung S, Weintraub S, Mesulam MM, Bigio EH, Gitelman DR, Fisher-Hubbard AO, Albin RL, Vinters HV. Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database. J Neuropathol Exp Neurol. 2016 Mar; 75(3):284-90. PMID: 26888304.
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      13. Mendez MF, Ringman J, Shapira JS. Impairments in the Face-Processing Network in Developmental Prosopagnosia and Semantic Dementia. Cogn Behav Neurol. 2015 Dec; 28(4):188-97. PMID: 26705265.
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      14. Avila J, Flowers A, Scott TM, Quilici J, Apostolova LG, Woo E, Ringman J, Razani J. Daily Activity Abilities in MCI, Alzheimer's Disease, and Healthy Controls. GeroPsych (Bern). 2015 Dec; 28(4):191-200. PMID: 27366145.
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      15. Yan L, Liu CY, Smith RX, Jog M, Langham M, Krasileva K, Chen Y, Ringman J, Wang DJ. Assessing intracranial vascular compliance using dynamic arterial spin labeling. Neuroimage. 2016 Jan 1; 124(Pt A):433-41. PMID: 26364865.
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      16. Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman J, Graff-Radford NR, Ghetti B, Farlow MR, Sperling R, Salloway S, Schofield PR, Masters CL, Martins RN, Rossor MN, Jucker M, Danek A, Förster S, Lane CA, Morris JC, Benzinger TL, Bateman RJ. Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology. 2015 Sep 1; 85(9):790-8. PMID: 26245925.
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      17. Grill JD, Bateman RJ, Buckles V, Oliver A, Morris JC, Masters CL, Klunk WE, Ringman J. A survey of attitudes toward clinical trials and genetic disclosure in autosomal dominant Alzheimer's disease. Alzheimers Res Ther. 2015; 7(1):50. PMID: 26203303.
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      18. Chen JA, Wang Q, Davis-Turak J, Li Y, Karydas AM, Hsu SC, Sears RL, Chatzopoulou D, Huang AY, Wojta KJ, Klein E, Lee J, Beekly DL, Boxer A, Faber KM, Haase CM, Miller J, Poon WW, Rosen A, Rosen H, Sapozhnikova A, Shapira J, Varpetian A, Foroud TM, Levenson RW, Levey AI, Kukull WA, Mendez MF, Ringman J, Chui H, Cotman C, DeCarli C, Miller BL, Geschwind DH, Coppola G. A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy. JAMA Neurol. 2015 Apr 1; 72(4):414-22. PMID: 25706306.
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      19. Korenman S, Finder SG, Ringman J. Conceptualization and assessment of vulnerability in a complex international Alzheimer's research study. Am J Bioeth. 2015 Apr; 15(4):87-9. PMID: 25856620.
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      20. Zhou Y, Ortiz F, Nuñez C, Elashoff D, Woo E, Apostolova LG, Wolf S, Casado M, Caceres N, Panchal H, Ringman J. Use of the MoCA in Detecting Early Alzheimer's Disease in a Spanish-Speaking Population with Varied Levels of Education. Dement Geriatr Cogn Dis Extra. 2015 Jan-Apr; 5(1):85-95. PMID: 25873930.
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      21. Monserrate AE, Ryman DC, Ma S, Xiong C, Noble JM, Ringman J, Morris JC, Danek A, Müller-Sarnowski F, Clifford DB, McDade EM, Brooks WS, Darby DG, Masters CL, Weston PS, Farlow MR, Graff-Radford NR, Salloway SP, Fagan AM, Oliver A, Bateman RJ. Factors associated with the onset and persistence of post-lumbar puncture headache. JAMA Neurol. 2015 Mar 1; 72(3):325-32. PMID: 25622095.
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      22. Ringman J, Liang LJ, Zhou Y, Vangala S, Teng E, Kremen S, Wharton D, Goate A, Marcus DS, Farlow M, Ghetti B, McDade E, Masters CL, Mayeux RP, Rossor M, Salloway S, Schofield PR, Cummings JL, Buckles V, Bateman R, Morris JC. Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network. Brain. 2015 Apr; 138(Pt 4):1036-45. PMID: 25688083.
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      23. Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD. Rarity of the Alzheimer Disease-Protective APP A673T Variant in the United States. JAMA Neurol. 2015 Feb 1; 72(2):209-16. PMID: 25531812.
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      24. Liu Q, Waltz S, Woodruff G, Ouyang J, Israel MA, Herrera C, Sarsoza F, Tanzi RE, Koo EH, Ringman J, Goldstein LS, Wagner SL, Yuan SH. Effect of Potent ?-Secretase Modulator in Human Neurons Derived From Multiple Presenilin 1-Induced Pluripotent Stem Cell Mutant Carriers. JAMA Neurol. 2014 Dec 1; 71(12):1481-9. PMID: 25285942.
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      25. Ringman J, Goate A, Masters CL, Cairns NJ, Danek A, Graff-Radford N, Ghetti B, Morris JC. Genetic heterogeneity in Alzheimer disease and implications for treatment strategies. Curr Neurol Neurosci Rep. 2014 Nov; 14(11):499. PMID: 25217249.
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      26. Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA. Effects of multiple genetic Loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov 1; 71(11):1394-404. PMID: 25199842.
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      27. Tinklenberg JR, Kraemer HC, Yaffe K, O'Hara R, Ringman J, Ashford JW, Yesavage JA, Taylor JL. Donepezil treatment in ethnically diverse patients with Alzheimer disease. Am J Geriatr Psychiatry. 2015 Apr; 23(4):384-90. PMID: 25747405.
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      28. Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman J, Salloway S, McDade E, Rossor MN, Ourselin S, Schofield PR, Masters CL, Martins RN, Weiner MW, Thompson PM, Fox NC, Koeppe RA, Jack CR, Mathis CA, Oliver A, Blazey TM, Moulder K, Buckles V, Hornbeck R, Chhatwal J, Schultz AP, Goate AM, Fagan AM, Cairns NJ, Marcus DS, Morris JC, Ances BM. Functional connectivity in autosomal dominant and late-onset Alzheimer disease. JAMA Neurol. 2014 Sep 1; 71(9):1111-22. PMID: 25069482.
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      29. Hurtz S, Woo E, Kebets V, Green AE, Zoumalan C, Wang B, Ringman J, Thompson PM, Apostolova LG. Age effects on cortical thickness in cognitively normal elderly individuals. Dement Geriatr Cogn Dis Extra. 2014 May; 4(2):221-7. PMID: 25177330.
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      30. Ringman J, Sachs MC, Zhou Y, Monsell SE, Saver JL, Vinters HV. Clinical predictors of severe cerebral amyloid angiopathy and influence of APOE genotype in persons with pathologically verified Alzheimer disease. JAMA Neurol. 2014 Jul 1; 71(7):878-83. PMID: 24797962.
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      31. Ryman DC, Acosta-Baena N, Aisen PS, Bird T, Danek A, Fox NC, Goate A, Frommelt P, Ghetti B, Langbaum JB, Lopera F, Martins R, Masters CL, Mayeux RP, McDade E, Moreno S, Reiman EM, Ringman J, Salloway S, Schofield PR, Sperling R, Tariot PN, Xiong C, Morris JC, Bateman RJ. Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis. Neurology. 2014 Jul 15; 83(3):253-60. PMID: 24928124.
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      32. Cummings JL, Ringman J, Vinters HV. Neuropathologic correlates of trial-related instruments for Alzheimer's disease. Am J Neurodegener Dis. 2014; 3(1):45-9. PMID: 24754002.
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      33. Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman J, Rossor MN, Salloway S, Schofield PR, Sperling RA, Marcus D, Cairns NJ, Buckles VD, Ladenson JH, Morris JC, Holtzman DM. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease. Sci Transl Med. 2014 Mar 5; 6(226):226ra30. PMID: 24598588.
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      34. McLaughlin PM, Wright MJ, Larocca M, Nguyen PT, Teng E, Apostolova LG, Ringman J, Zhou Y, Cummings JL, Woo E. The "Alzheimer's type" profile of semantic clustering in amnestic mild cognitive impairment. J Int Neuropsychol Soc. 2014 Apr; 20(4):402-12. PMID: 24521694.
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      35. Fitten LJ, Ortiz F, Fairbanks L, Bartzokis G, Lu P, Klein E, Coppola G, Ringman J. Younger age of dementia diagnosis in a Hispanic population in southern California. Int J Geriatr Psychiatry. 2014 Jun; 29(6):586-93. PMID: 24478258.
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      36. Ting SK, Benzinger T, Kepe V, Fagan A, Coppola G, Porter V, Hecimovic S, Chakraverty S, Alvarez-Retuerto AI, Goate A, Ringman J. A novel PSEN1 mutation (I238M) associated with early-onset Alzheimer's disease in an African-American woman. J Alzheimers Dis. 2014; 40(2):271-5. PMID: 24413619.
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      37. Benzinger TL, Blazey T, Jack CR, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, Christensen JJ, Ercole L, Hornbeck RC, Farrar AM, Aldea P, Jasielec MS, Owen CJ, Xie X, Mayeux R, Brickman A, McDade E, Klunk W, Mathis CA, Ringman J, Thompson PM, Ghetti B, Saykin AJ, Sperling RA, Johnson KA, Salloway S, Correia S, Schofield PR, Masters CL, Rowe C, Villemagne VL, Martins R, Ourselin S, Rossor MN, Fox NC, Cash DM, Weiner MW, Holtzman DM, Buckles VD, Moulder K, Morris JC. Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):E4502-9. PMID: 24194552.
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      38. Cash DM, Ridgway GR, Liang Y, Ryan NS, Kinnunen KM, Yeatman T, Malone IB, Benzinger TL, Jack CR, Thompson PM, Ghetti BF, Saykin AJ, Masters CL, Ringman J, Salloway SP, Schofield PR, Sperling RA, Cairns NJ, Marcus DS, Xiong C, Bateman RJ, Morris JC, Rossor MN, Ourselin S, Fox NC. The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study. Neurology. 2013 Oct 15; 81(16):1425-33. PMID: 24049139.
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      39. Kilroy E, Apostolova L, Liu C, Yan L, Ringman J, Wang DJ. Reliability of two-dimensional and three-dimensional pseudo-continuous arterial spin labeling perfusion MRI in elderly populations: comparison with 15O-water positron emission tomography. J Magn Reson Imaging. 2014 Apr; 39(4):931-9. PMID: 24038544.
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      40. Chhatwal JP, Schultz AP, Johnson K, Benzinger TL, Jack C, Ances BM, Sullivan CA, Salloway SP, Ringman J, Koeppe RA, Marcus DS, Thompson P, Saykin AJ, Correia S, Schofield PR, Rowe CC, Fox NC, Brickman AM, Mayeux R, McDade E, Bateman R, Fagan AM, Goate AM, Xiong C, Buckles VD, Morris JC, Sperling RA. Impaired default network functional connectivity in autosomal dominant Alzheimer disease. Neurology. 2013 Aug 20; 81(8):736-44. PMID: 23884042.
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      41. Hooper M, Grill JD, Rodriguez-Agudelo Y, Medina LD, Fox M, Alvarez-Retuerto AI, Wharton D, Brook J, Ringman J. The impact of the availability of prevention studies on the desire to undergo predictive testing in persons at risk for autosomal dominant Alzheimer's disease. Contemp Clin Trials. 2013 Sep; 36(1):256-62. PMID: 23876673.
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      42. Teng E, Leone-Friedman J, Lee GJ, Woo S, Apostolova LG, Harrell S, Ringman J, Lu PH. Similar verbal fluency patterns in amnestic mild cognitive impairment and Alzheimer's disease. Arch Clin Neuropsychol. 2013 Aug; 28(5):400-10. PMID: 23752677.
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      43. Braskie MN, Kohannim O, Jahanshad N, Chiang MC, Barysheva M, Toga AW, Ringman J, Montgomery GW, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Thompson PM. Relation between variants in the neurotrophin receptor gene, NTRK3, and white matter integrity in healthy young adults. Neuroimage. 2013 Nov 15; 82:146-53. PMID: 23727532.
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      44. Ringman J, Coppola G. New genes and new insights from old genes: update on Alzheimer disease. Continuum (Minneap Minn). 2013 Apr; 19(2 Dementia):358-71. PMID: 23558482.
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      45. O'Neill J, Gorbis E, Feusner JD, Yip JC, Chang S, Maidment KM, Levitt JG, Salamon N, Ringman J, Saxena S. Effects of intensive cognitive-behavioral therapy on cingulate neurochemistry in obsessive-compulsive disorder. J Psychiatr Res. 2013 Apr; 47(4):494-504. PMID: 23290560.
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      46. Mizwicki MT, Liu G, Fiala M, Magpantay L, Sayre J, Siani A, Mahanian M, Weitzman R, Hayden EY, Rosenthal MJ, Nemere I, Ringman J, Teplow DB. 1a,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-ß phagocytosis and inflammation in Alzheimer's disease patients. J Alzheimers Dis. 2013; 34(1):155-70. PMID: 23186989.
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      47. Ringman J, Tomic JL, Coppola G, Elashoff D, Gylys KH, Glabe CG. Conformation-dependent oligomers in cerebrospinal fluid of presymptomatic familial Alzheimer's disease mutation carriers. Dement Geriatr Cogn Dis Extra. 2012 Jan; 2(1):652-7. PMID: 23341831.
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      48. Liu CY, Krishnan AP, Yan L, Smith RX, Kilroy E, Alger JR, Ringman J, Wang DJ. Complexity and synchronicity of resting state blood oxygenation level-dependent (BOLD) functional MRI in normal aging and cognitive decline. J Magn Reson Imaging. 2013 Jul; 38(1):36-45. PMID: 23225622.
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      49. Ringman J, Frautschy SA, Teng E, Begum AN, Bardens J, Beigi M, Gylys KH, Badmaev V, Heath DD, Apostolova LG, Porter V, Vanek Z, Marshall GA, Hellemann G, Sugar C, Masterman DL, Montine TJ, Cummings JL, Cole GM. Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study. Alzheimers Res Ther. 2012; 4(5):43. PMID: 23107780.
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      50. Lee GJ, Lu PH, Medina LD, Rodriguez-Agudelo Y, Melchor S, Coppola G, Braskie MN, Hua X, Apostolova LG, Leow AD, Thompson PM, Ringman J. Regional brain volume differences in symptomatic and presymptomatic carriers of familial Alzheimer's disease mutations. J Neurol Neurosurg Psychiatry. 2013 Feb; 84(2):154-62. PMID: 23085935.
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      51. Morris JC, Aisen PS, Bateman RJ, Benzinger TL, Cairns NJ, Fagan AM, Ghetti B, Goate AM, Holtzman DM, Klunk WE, McDade E, Marcus DS, Martins RN, Masters CL, Mayeux R, Oliver A, Quaid K, Ringman J, Rossor MN, Salloway S, Schofield PR, Selsor NJ, Sperling RA, Weiner MW, Xiong C, Moulder KL, Buckles VD. Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clin Investig (Lond). 2012 Oct 1; 2(10):975-984. PMID: 23139856.
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      52. Prado E, Paholpak P, Ngo M, Porter V, Apostolova LG, Marrocos R, Ringman J. Agitation and psychosis associated with dementia with lewy bodies exacerbated by modafinil use. Am J Alzheimers Dis Other Demen. 2012 Nov; 27(7):468-73. PMID: 22892657.
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      53. Braskie MN, Medina LD, Rodriguez-Agudelo Y, Geschwind DH, Macias-Islas MA, Thompson PM, Cummings JL, Bookheimer SY, Ringman J. Memory performance and fMRI signal in presymptomatic familial Alzheimer's disease. Hum Brain Mapp. 2013 Dec; 34(12):3308-19. PMID: 22806961.
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      54. Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, Aisen PS, Ghetti B, Klunk WE, McDade E, Martins RN, Masters CL, Mayeux R, Ringman J, Rossor MN, Schofield PR, Sperling RA, Salloway S, Morris JC. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med. 2012 Aug 30; 367(9):795-804. PMID: 22784036.
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      55. Galasko DR, Peskind E, Clark CM, Quinn JF, Ringman J, Jicha GA, Cotman C, Cottrell B, Montine TJ, Thomas RG, Aisen P. Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures. Arch Neurol. 2012 Jul; 69(7):836-41. PMID: 22431837.
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      56. Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8. PMID: 22722634.
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      57. Ringman J, Teplow DB, Villemagne VL. The exception makes the rule: not all Aß plaques are created equal. Neurology. 2012 Jul 17; 79(3):206-7. PMID: 22700807.
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      58. Ringman J, Elashoff D, Geschwind DH, Welsh BT, Gylys KH, Lee C, Cummings JL, Cole GM. Plasma signaling proteins in persons at genetic risk for Alzheimer disease: influence of APOE genotype. Arch Neurol. 2012 Jun; 69(6):757-64. PMID: 22689192.
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      59. Ringman J, Fithian AT, Gylys K, Cummings JL, Coppola G, Elashoff D, Pratico D, Moskovitz J, Bitan G. Plasma methionine sulfoxide in persons with familial Alzheimer's disease mutations. Dement Geriatr Cogn Disord. 2012; 33(4):219-25. PMID: 22584618.
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      60. Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, Cotman CW, Decarli CS, Levey AI, Ringman J, Mendez MF, Chui HC, Le Ber I, Brice A, Lupton MK, Preza E, Lovestone S, Powell J, Graff-Radford N, Petersen RC, Boeve BF, Lippa CF, Bigio EH, Mackenzie I, Finger E, Kertesz A, Caselli RJ, Gearing M, Juncos JL, Ghetti B, Spina S, Bordelon YM, Tourtellotte WW, Frosch MP, Vonsattel JP, Zarow C, Beach TG, Albin RL, Lieberman AP, Lee VM, Trojanowski JQ, Van Deerlin VM, Bird TD, Galasko DR, Masliah E, White CL, Troncoso JC, Hannequin D, Boxer AL, Geschwind MD, Kumar S, Mandelkow EM, Wszolek ZK, Uitti RJ, Dickson DW, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet. 2012 Aug 1; 21(15):3500-12. PMID: 22556362.
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      61. Braskie MN, Jahanshad N, Stein JL, Barysheva M, Johnson K, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Ringman J, Toga AW, Thompson PM. Relationship of a variant in the NTRK1 gene to white matter microstructure in young adults. J Neurosci. 2012 Apr 25; 32(17):5964-72. PMID: 22539856.
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      62. Grill JD, Di L, Lu PH, Lee C, Ringman J, Apostolova LG, Chow N, Kohannim O, Cummings JL, Thompson PM, Elashoff D. Estimating sample sizes for predementia Alzheimer's trials based on the Alzheimer's Disease Neuroimaging Initiative. Neurobiol Aging. 2013 Jan; 34(1):62-72. PMID: 22503160.
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      63. Joshi A, Ringman J, Lee AS, Juarez KO, Mendez MF. Comparison of clinical characteristics between familial and non-familial early onset Alzheimer's disease. J Neurol. 2012 Oct; 259(10):2182-8. PMID: 22460587.
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      64. Ringman J, Coppola G, Elashoff D, Rodriguez-Agudelo Y, Medina LD, Gylys K, Cummings JL, Cole GM. Cerebrospinal fluid biomarkers and proximity to diagnosis in preclinical familial Alzheimer's disease. Dement Geriatr Cogn Disord. 2012; 33(1):1-5. PMID: 22343824.
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      65. Ringman J, Schulman H, Becker C, Jones T, Bai Y, Immermann F, Cole G, Sokolow S, Gylys K, Geschwind DH, Cummings JL, Wan HI. Proteomic changes in cerebrospinal fluid of presymptomatic and affected persons carrying familial Alzheimer disease mutations. Arch Neurol. 2012 Jan; 69(1):96-104. PMID: 22232349.
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      66. Apostolova LG, Hwang KS, Medina LD, Green AE, Braskie MN, Dutton RA, Lai J, Geschwind DH, Cummings JL, Thompson PM, Ringman J. Cortical and hippocampal atrophy in patients with autosomal dominant familial Alzheimer's disease. Dement Geriatr Cogn Disord. 2011; 32(2):118-25. PMID: 21952501.
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      67. Medina LD, Rodriguez-Agudelo Y, Geschwind DH, Gilbert PE, Liang LJ, Cummings JL, Ringman J. Propositional density and apolipoprotein E genotype among persons at risk for familial Alzheimer's disease. Dement Geriatr Cogn Disord. 2011; 32(3):188-92. PMID: 22134129.
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      68. Grill JD, Ringman J. Should persons with autosomal dominant AD be included in clinical trials? Alzheimers Res Ther. 2011; 3(3):18. PMID: 21609419.
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      69. Braskie MN, Jahanshad N, Stein JL, Barysheva M, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Ringman J, Toga AW, Thompson PM. Common Alzheimer's disease risk variant within the CLU gene affects white matter microstructure in young adults. J Neurosci. 2011 May 4; 31(18):6764-70. PMID: 21543606.
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      70. Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman J, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41. PMID: 21460841.
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      71. Braskie MN, Ringman J, Thompson PM. Neuroimaging measures as endophenotypes in Alzheimer's disease. Int J Alzheimers Dis. 2011; 2011:490140. PMID: 21547229.
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      72. Ringman J. Setting the stage for prevention of familial Alzheimer's disease. Lancet Neurol. 2011 Mar; 10(3):200-1. PMID: 21296021.
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      73. Bateman RJ, Aisen PS, De Strooper B, Fox NC, Lemere CA, Ringman J, Salloway S, Sperling RA, Windisch M, Xiong C. Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease. Alzheimers Res Ther. 2011; 3(1):1. PMID: 21211070.
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      74. Maalouf M, Ringman J, Shi J. An update on the diagnosis and management of dementing conditions. Rev Neurol Dis. 2011; 8(3-4):e68-87. PMID: 22249572.
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      75. Braskie MN, Medina LD, Rodriguez-Agudelo Y, Geschwind DH, Macias-Islas MA, Cummings JL, Bookheimer SY, Ringman J. Increased fMRI signal with age in familial Alzheimer's disease mutation carriers. Neurobiol Aging. 2012 Feb; 33(2):424.e11-21. PMID: 21129823.
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      76. Ringman J, Gylys KH, Medina LD, Fox M, Kepe V, Flores DL, Apostolova LG, Barrio JR, Small G, Silverman DH, Siu E, Cederbaum S, Hecimovic S, Malnar M, Chakraverty S, Goate AM, Bird TD, Leverenz JB. Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation. Neurosci Lett. 2011 Jan 10; 487(3):287-92. PMID: 21094210.
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      77. Ringman J, Kwon E, Flores DL, Rotko C, Mendez MF, Lu P. The use of profanity during letter fluency tasks in frontotemporal dementia and Alzheimer disease. Cogn Behav Neurol. 2010 Sep; 23(3):159-64. PMID: 20829665.
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      78. Ringman J, Medina LD, Braskie M, Rodriguez-Agudelo Y, Geschwind DH, Macias-Islas MA, Cummings JL, Bookheimer S. Effects of risk genes on BOLD activation in presymptomatic carriers of familial Alzheimer's disease mutations during a novelty encoding task. Cereb Cortex. 2011 Apr; 21(4):877-83. PMID: 20729396.
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      79. Portelius E, Andreasson U, Ringman J, Buerger K, Daborg J, Buchhave P, Hansson O, Harmsen A, Gustavsson MK, Hanse E, Galasko D, Hampel H, Blennow K, Zetterberg H. Distinct cerebrospinal fluid amyloid beta peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease. Mol Neurodegener. 2010; 5:2. PMID: 20145736.
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      80. Ringman J, Pope W, Salamon N. Insensitivity of visual assessment of hippocampal atrophy in familial Alzheimer's disease. J Neurol. 2010 May; 257(5):839-42. PMID: 20047059.
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      81. Cummings JL, Ringman J, Metz K. Mary S. Easton Center of Alzheimer's Disease Research at UCLA: advancing the therapeutic imperative. J Alzheimers Dis. 2010; 19(2):375-88. PMID: 20110588.
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      82. Ringman J, Medina LD, Rodriguez-Agudelo Y, Chavez M, Lu P, Cummings JL. Current concepts of mild cognitive impairment and their applicability to persons at-risk for familial Alzheimer's disease. Curr Alzheimer Res. 2009 Aug; 6(4):341-6. PMID: 19689233.
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      83. Ma QL, Galasko DR, Ringman J, Vinters HV, Edland SD, Pomakian J, Ubeda OJ, Rosario ER, Teter B, Frautschy SA, Cole GM. Reduction of SorLA/LR11, a sorting protein limiting beta-amyloid production, in Alzheimer disease cerebrospinal fluid. Arch Neurol. 2009 Apr; 66(4):448-57. PMID: 19364929.
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      84. Ringman J, Grill J, Rodriguez-Agudelo Y, Chavez M, Xiong C. Commentary on "a roadmap for the prevention of dementia II: Leon Thal Symposium 2008." Prevention trials in persons at risk for dominantly inherited Alzheimer's disease: opportunities and challenges. Alzheimers Dement. 2009 Mar; 5(2):166-71. PMID: 19328453.
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      85. Teng E, Ringman J, Ross LK, Mulnard RA, Dick MB, Bartzokis G, Davies HD, Galasko D, Hewett L, Mungas D, Reed BR, Schneider LS, Segal-Gidan F, Yaffe K, Cummings JL. Diagnosing depression in Alzheimer disease with the national institute of mental health provisional criteria. Am J Geriatr Psychiatry. 2008 Jun; 16(6):469-77. PMID: 18515691.
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      86. Ringman J, Mozaffar T. Myopathy associated with chronic orlistat consumption: a case report. Neuromuscul Disord. 2008 May; 18(5):410-2. PMID: 18430571.
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      87. Ringman J, Romano JD, Medina LD, Rodriguez-Agudelo Y, Schaffer B, Varpetian A, Ortiz F, Fitten LJ, Cummings JL, Baloh RW. Increased prevalence of significant recurrent headache in preclinical familial Alzheimer's disease mutation carriers. Dement Geriatr Cogn Disord. 2008; 25(4):380-4. PMID: 18376127.
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      88. Ringman J, Rao PN, Lu PH, Cederbaum S. Mosaicism for trisomy 21 in a patient with young-onset dementia: a case report and brief literature review. Arch Neurol. 2008 Mar; 65(3):412-5. PMID: 18332257.
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      89. Jarvik L, LaRue A, Blacker D, Gatz M, Kawas C, McArdle JJ, Morris JC, Mortimer JA, Ringman J, Ercoli L, Freimer N, Gokhman I, Manly JJ, Plassman BL, Rasgon N, Roberts JS, Sunderland T, Swan GE, Wolf PA, Zonderman AB. Children of persons with Alzheimer disease: what does the future hold? Alzheimer Dis Assoc Disord. 2008 Jan-Mar; 22(1):6-20. PMID: 18317242.
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      90. Ringman J. The Huntington disease of woody guthrie: another man done gone. Cogn Behav Neurol. 2007 Dec; 20(4):238-43. PMID: 18091075.
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      91. Fiala M, Liu PT, Espinosa-Jeffrey A, Rosenthal MJ, Bernard G, Ringman J, Sayre J, Zhang L, Zaghi J, Dejbakhsh S, Chiang B, Hui J, Mahanian M, Baghaee A, Hong P, Cashman J. Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin. Proc Natl Acad Sci U S A. 2007 Jul 31; 104(31):12849-54. PMID: 17652175.
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      92. Ringman J, O'Neill J, Geschwind D, Medina L, Apostolova LG, Rodriguez Y, Schaffer B, Varpetian A, Tseng B, Ortiz F, Fitten J, Cummings JL, Bartzokis G. Diffusion tensor imaging in preclinical and presymptomatic carriers of familial Alzheimer's disease mutations. Brain. 2007 Jul; 130(Pt 7):1767-76. PMID: 17522104.
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      93. Ringman J, Rodriguez Y, Diaz-Olavarrieta C, Chavez M, Thompson M, Fairbanks L, Paz F, Varpetian A, Chaparro H, Macias-Islas MA, Murrell J, Ghetti B, Kawas C. Performance on MMSE sub-items and education level in presenilin-1 mutation carriers without dementia. Int Psychogeriatr. 2007 Apr; 19(2):323-32. PMID: 16805926.
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      94. Nelson LD, Scheibel KE, Ringman J, Sayre JW. An experimental approach to detecting dementia in Down syndrome: a paradigm for Alzheimer's disease. Brain Cogn. 2007 Jun; 64(1):92-103. PMID: 17383786.
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      95. Ringman J. Serendipitous improvement in the Yips associated with memantine use. Mov Disord. 2007 Mar 15; 22(4):598-9. PMID: 17266082.
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      96. Ringman J, Hillis A. Visualizing language deterioration in progressive aphasias. Neurology. 2006 Nov 28; 67(10):1738-9. PMID: 17130401.
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      97. Ringman J. Donepezil improves cognitive function and reduces decline in activities of daily living in people with severe Alzheimer's disease. Evid Based Ment Health. 2006 Nov; 9(4):104. PMID: 17065301.
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      98. Murrell J, Ghetti B, Cochran E, Macias-Islas MA, Medina L, Varpetian A, Cummings JL, Mendez MF, Kawas C, Chui H, Ringman J. The A431E mutation in PSEN1 causing familial Alzheimer's disease originating in Jalisco State, Mexico: an additional fifteen families. Neurogenetics. 2006 Nov; 7(4):277-9. PMID: 16897084.
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      99. Lee P, Medina L, Ringman J. The Thr354Ile substitution in PSEN1:: disease-causing mutation or polymorphism? Neurology. 2006 Jun 27; 66(12):1955-6. PMID: 16801675.
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      100. McMurtray AM, Ringman J, Chao SZ, Licht E, Saul RE, Mendez MF. Family history of dementia in early-onset versus very late-onset Alzheimer's disease. Int J Geriatr Psychiatry. 2006 Jun; 21(6):597-8. PMID: 16783800.
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      101. Ringman J, Cummings JL. Current and emerging pharmacological treatment options for dementia. Behav Neurol. 2006; 17(1):5-16. PMID: 16720956.
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      102. Ringman J. What the study of persons at risk for familial Alzheimer's disease can tell us about the earliest stages of the disorder: a review. J Geriatr Psychiatry Neurol. 2005 Dec; 18(4):228-33. PMID: 16306245.
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      103. Ringman J, Flores DL. Earlier Alzheimer onset in Latino persons: ethnic difference vs selection bias. Arch Neurol. 2005 Nov; 62(11):1786-7. PMID: 16286560.
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      104. Ringman J, Grant AC. Carbonic anhydrase inhibitors and amobarbital resistance. Epilepsia. 2005 Aug; 46(8):1333. PMID: 16060953.
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      105. Fiala M, Lin J, Ringman J, Kermani-Arab V, Tsao G, Patel A, Lossinsky AS, Graves MC, Gustavson A, Sayre J, Sofroni E, Suarez T, Chiappelli F, Bernard G. Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients. J Alzheimers Dis. 2005 Jun; 7(3):221-32; discussion 255-62. PMID: 16006665.
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      106. Ringman J, Frautschy SA, Cole GM, Masterman DL, Cummings JL. A potential role of the curry spice curcumin in Alzheimer's disease. Curr Alzheimer Res. 2005 Apr; 2(2):131-6. PMID: 15974909.
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      107. Matsumoto J, Saver JL, Brennan KC, Ringman J. Mitochondrial encephalomyopathy with lactic acidosis and stroke (MELAS). Rev Neurol Dis. 2005; 2(1):30-4. PMID: 16400302.
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      108. Peng Y, Crumley R, Ringman J. Spasmodic dysphonia in a patient with the A to G transition at nucleotide 8344 in mitochondrial DNA. Mov Disord. 2003 Jun; 18(6):716-8. PMID: 12784281.
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      109. Ringman J, Diaz-Olavarrieta C, Rodriguez Y, Fairbanks L, Cummings JL. The prevalence and correlates of neuropsychiatric symptoms in a population with Parkinson's disease in Mexico. Neuropsychiatry Neuropsychol Behav Neurol. 2002 Jun; 15(2):99-105. PMID: 12050472.
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