Jian Xu, PhD

Title(s)Associate Professor
SchoolHerman Ostrow School of Dentistry of Usc
AddressClinical Science Annex
Health Sciences Campus
Los Angeles CA 90089-9062
Phone+1 323 442 4835
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    Collapse Biography 
    Collapse Awards and Honors
    2011  - 2014American Heart Association National Scientist Development Grant
    2012FASEB Biological Methylation Conference Best Seminar Award
    2011Tokyo Global Center of Excellence Retreat Poster Award
    2009  - 2010Foundation Independent Postdoctoral Research Fellowship
    2007  - 2009American Heart Association Postdoctoral Fellowship
    2003University of Cincinnati Graduate Student Poster Forum, Poster Award
    2001  - 2003American Heart Association Pre-doctoral Fellowship
    2000Peking University Health Science Center Undergraduate Dissertation Award
    1995  - 2000Peking University Outstanding Student Scholarship

    Collapse Overview 

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Role of Patient Sorting in Avoidable Hospital Stays in Medicare Advantage vs Traditional Medicare. JAMA Health Forum. 2023 Nov 03; 4(11):e233931. Xu JF, Anderson KE, Liu A, Miller BJ, Polsky D. PMID: 37948062; PMCID: PMC10638641.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Cellular pathways influenced by protein arginine methylation: Implications for cancer. Mol Cell. 2021 11 04; 81(21):4357-4368. Xu J, Richard S. PMID: 34619091; PMCID: PMC8571027.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    3. Does Smad6 methylation control BMP signaling in cancer? Cell Cycle. 2014; 13(8):1209-10. Xu J, Derynck R. PMID: 24621505; PMCID: PMC4049950.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    4. Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2014 Mar; 15(3):178-96. Lamouille S, Xu J, Derynck R. PMID: 24556840; PMCID: PMC4240281.
      View in: PubMed   Mentions: 3736     Fields:    Translation:HumansCells
    5. Arginine Methylation Initiates BMP-Induced Smad Signaling. Mol Cell. 2013 Jul 11; 51(1):5-19. Xu J, Wang AH, Oses-Prieto J, Makhijani K, Katsuno Y, Pei M, Yan L, Zheng YG, Burlingame A, Brückner K, Derynck R. PMID: 23747011; PMCID: PMC3951972.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    6. CIB1 is a regulator of pathological cardiac hypertrophy. Nat Med. 2010 Aug; 16(8):872-9. Heineke J, Auger-Messier M, Correll RN, Xu J, Benard MJ, Yuan W, Drexler H, Parise LV, Molkentin JD. PMID: 20639889; PMCID: PMC2917617.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    7. Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure. Circulation. 2010 Jan 26; 121(3):419-25. Heineke J, Auger-Messier M, Xu J, Sargent M, York A, Welle S, Molkentin JD. PMID: 20065166; PMCID: PMC2823256.
      View in: PubMed   Mentions: 116     Fields:    Translation:AnimalsCells
    8. TACE-mediated ectodomain shedding of the type I TGF-beta receptor downregulates TGF-beta signaling. Mol Cell. 2009 Jul 10; 35(1):26-36. Liu C, Xu P, Lamouille S, Xu J, Derynck R. PMID: 19595713; PMCID: PMC2740991.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    9. TGF-beta-induced epithelial to mesenchymal transition. Cell Res. 2009 Feb; 19(2):156-72. Xu J, Lamouille S, Derynck R. PMID: 19153598; PMCID: PMC4720263.
      View in: PubMed   Mentions: 1303     Fields:    Translation:Cells
    10. Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart. J Clin Invest. 2007 Nov; 117(11):3198-210. Heineke J, Auger-Messier M, Xu J, Oka T, Sargent MA, York A, Klevitsky R, Vaikunth S, Duncan SA, Aronow BJ, Robbins J, Crombleholme TM, Cromblehol TM, Molkentin JD. PMID: 17975667; PMCID: PMC2045611.
      View in: PubMed   Mentions: 112     Fields:    Translation:AnimalsCells
    11. Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling. Circ Res. 2007 Aug 03; 101(3):313-21. Oka T, Xu J, Kaiser RA, Melendez J, Hambleton M, Sargent MA, Lorts A, Brunskill EW, Dorn GW, Conway SJ, Aronow BJ, Robbins J, Molkentin JD. PMID: 17569887; PMCID: PMC2680305.
      View in: PubMed   Mentions: 278     Fields:    Translation:AnimalsCells
    12. Re-employment of developmental transcription factors in adult heart disease. Semin Cell Dev Biol. 2007 Feb; 18(1):117-31. Oka T, Xu J, Molkentin JD. PMID: 17161634; PMCID: PMC1855184.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimals
    13. Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice. J Biol Chem. 2006 Apr 07; 281(14):9152-62. Xu J, Gong NL, Bodi I, Aronow BJ, Backx PH, Molkentin JD. PMID: 16469744.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    14. The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury. Circ Res. 2006 Feb 17; 98(3):351-60. Kempf T, Eden M, Strelau J, Naguib M, Willenbockel C, Tongers J, Heineke J, Kotlarz D, Xu J, Molkentin JD, Niessen HW, Drexler H, Wollert KC. PMID: 16397141.
      View in: PubMed   Mentions: 258     Fields:    Translation:HumansAnimalsCells
    15. GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation. Circ Res. 2006 Feb 17; 98(3):342-50. Xu J, Kimball TR, Lorenz JN, Brown DA, Bauskin AR, Klevitsky R, Hewett TE, Breit SN, Molkentin JD. PMID: 16397142.
      View in: PubMed   Mentions: 199     Fields:    Translation:AnimalsCells
    16. The DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitment. Mol Cell Biol. 2005 Nov; 25(22):9936-48. Dai YS, Xu J, Molkentin JD. PMID: 16260608; PMCID: PMC1280278.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    17. Calreticulin signals upstream of calcineurin and MEF2C in a critical Ca(2+)-dependent signaling cascade. J Cell Biol. 2005 Jul 04; 170(1):37-47. Lynch J, Guo L, Gelebart P, Chilibeck K, Xu J, Molkentin JD, Agellon LB, Michalak M. PMID: 15998798; PMCID: PMC2171392.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    18. Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy. Circ Res. 2004 Jan 09; 94(1):110-8. Wilkins BJ, Dai YS, Bueno OF, Parsons SA, Xu J, Plank DM, Jones F, Kimball TR, Molkentin JD. PMID: 14656927.
      View in: PubMed   Mentions: 350     Fields:    Translation:AnimalsCells
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