Loading...
Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Jeffrey A Hagen, MD

    TitleAssociate Professor of Clinical Surgery
    SchoolKeck School of Medicine of USC
    DepartmentSurgery
    AddressHCC 514
    Health Sciences Campus
    Los Angeles California 90089-9202
    Phone+1 323 442 9066
    vCardDownload vCard

      Collapse Overview 
      Collapse Overview
      Dr. Jeffrey A. Hagen, MD is Director of the General Surgery Residency Program at the Keck School of Medicine of the University of Southern California. He specializes in the field of General Thoracic Surgery, which encompasses benign and malignant diseases of the esophagus, lungs, mediastinum and pleura/chest wall. He has extensive experience in both complex open surgical procedures and in the field of minimally invasive surgery of the chest. The Division of Thoracic Surgery that he leads is nationally and internationally recognized for their experience in esophageal and foregut surgery, contributing hundreds of papers, review articles and book chapters to our knowledge of the field.

      He leads the team of surgeons at the Keck Hospital of USC in the rapidly expanding robotic thoracic surgery program using the Da Vinci system. This approach allows the surgeons to perform resections of the lungs (lobectomy) and tumors of the mediastinum (such as thymoma) with greater precision than can be achieved using standard VATS techniques and less discomfort and shorter hospital stays than traditional open surgery. Dr. Hagen also leads the USC Multidisciplinary Lung Cancer Management Program – one of the few programs in the country where a truly multi-specialty clinic exists to efficiently evaluate patients known or suspected to have cancer of the lung. Patients can be simultaneously seen by specialists in Thoracic Surgery, Medical Oncology, Pulmonary Medicine and/or Radiation Oncology to allow us to provide the ultimate in comprehensive and personalized care to our patients.

      Dr. Hagen completed his General Surgery training at Creighton University before pursuing specialty training in Esophageal and Foregut Surgery at the University of Southern California under the guidance of Dr. Tom DeMeester. He then obtained his Thoracic Surgery training at the Barnes Hospital - Washington University program in St. Louis before joining the faculty at USC in 1994.

      Dr. Hagen’s research interests include assessment of predictors of outcome in the management of cancer of the esophagus and non-small cell cancer of the lung. He is also investigating strategies for early detection of lung cancer using unique DNA methylation signatures for lung cancer developed at USC. He has presented at numerous national and international medical and surgical societies, he serves on the review panels for more than a dozen scientific journals and he has more than 100 peer reviewed publications.


      Collapse ORNG Applications 
      Collapse Websites
      Collapse Required Scholarly Project Mentor

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Worrell SG, Alicuben ET, Oh DS, Hagen J, DeMeester SR. Accuracy of Clinical Staging and Outcome With Primary Resection for Local-Regionally Limited Esophageal Adenocarcinoma. Ann Surg. 2017 Feb 01. PMID: 28151801.
        View in: PubMed
      2. Schwameis K, Zehetner J, Rona K, Crookes P, Bildzukewicz N, Oh DS, Ro G, Ross K, Sandhu K, Katkhouda N, Hagen J, Lipham JC. Post-Nissen Dysphagia and Bloating Syndrome: Outcomes After Conversion to Toupet Fundoplication. J Gastrointest Surg. 2016 Nov 10. PMID: 27834011.
        View in: PubMed
      3. Dissanayake SN, Hagen J, Fedenko A, Lee C. Calcifying Fibrous Pseudotumor of the Posterior Mediastinum With Encapsulation of the Thoracic Duct. Ann Thorac Surg. 2016 Jul; 102(1):e39-40. PMID: 27343527.
        View in: PubMed
      4. Alnoor M, Boys JA, Worrell SG, Oh DS, Hagen J, DeMeester SR. Timing and Pattern of Recurrence after Gastrectomy for Adenocarcinoma. Am Surg. 2015 Oct; 81(10):1057-60. PMID: 26463308.
        View in: PubMed
      5. Boys JA, Oh DS, Lewis JS, DeMeester SR, Hagen J. Esophageal Adenocarcinoma in Patients Younger than 40 Years: A Two-Decade Experience at a Public and Private Hospital. Am Surg. 2015 Oct; 81(10):974-8. PMID: 26463292.
        View in: PubMed
      6. Greene CL, McFadden PM, Oh DS, Chang EJ, Hagen J. Long-Term Outcome of the Treatment of Zenker's Diverticulum. Ann Thorac Surg. 2015 Sep; 100(3):975-8. PMID: 26209492.
        View in: PubMed
      7. Boys JA, Alicuben ET, DeMeester MJ, Worrell SG, Oh DS, Hagen J, DeMeester SR. Public perceptions on robotic surgery, hospitals with robots, and surgeons that use them. Surg Endosc. 2016 Apr; 30(4):1310-6. PMID: 26173543.
        View in: PubMed
      8. Zehetner J, DeMeester SR, Alicuben ET, Oh DS, Lipham JC, Hagen J, DeMeester TR. Intraoperative Assessment of Perfusion of the Gastric Graft and Correlation With Anastomotic Leaks After Esophagectomy. Ann Surg. 2015 Jul; 262(1):74-8. PMID: 25029436.
        View in: PubMed
      9. Hagen J. Diffusion-weighted magnetic resonance imaging may identify candidates for alternatives to lobectomy for early stage lung cancer. J Thorac Cardiovasc Surg. 2015 Apr; 149(4):997. PMID: 25906714.
        View in: PubMed
      10. Greene CL, Chang EJ, Oh DS, Worrell SG, Hagen J, DeMeester SR. High resolution manometry sub-classification of Achalasia: does it really matter? : Does Achalasia sub-classification matter? Surg Endosc. 2015 Jun; 29(6):1363-7. PMID: 25249148.
        View in: PubMed
      11. Greene CL, DeMeester SR, Augustin F, Worrell SG, Oh DS, Hagen J, DeMeester TR. Long-term quality of life and alimentary satisfaction after esophagectomy with colon interposition. Ann Thorac Surg. 2014 Nov; 98(5):1713-20. PMID: 25258155.
        View in: PubMed
      12. Worrell SG, Oh DS, Greene CL, DeMeester SR, Hagen J. Acute esophageal necrosis: a case series and long-term follow-up. Ann Thorac Surg. 2014 Jul; 98(1):341-2. PMID: 24996722.
        View in: PubMed
      13. Hagen J. Invited commentary. Ann Thorac Surg. 2014 Jun; 97(6):1973-4. PMID: 24882283.
        View in: PubMed
      14. Greene CL, Demeester SR, Worrell SG, Oh DS, Hagen J, Demeester TR. Alimentary satisfaction, gastrointestinal symptoms, and quality of life 10 or more years after esophagectomy with gastric pull-up. J Thorac Cardiovasc Surg. 2014 Mar; 147(3):909-14. PMID: 24332098.
        View in: PubMed
      15. Worrell SG, Oh DS, Greene CL, Demeester SR, Hagen J. Endoscopic ultrasound staging of stenotic esophageal cancers may be unnecessary to determine the need for neoadjuvant therapy. J Gastrointest Surg. 2014 Feb; 18(2):318-20. PMID: 24190248.
        View in: PubMed
      16. Oh DS, Cho I, Karamian B, DeMeester SR, Hagen J. Early adoption of robotic pulmonary lobectomy: feasibility and initial outcomes. Am Surg. 2013 Oct; 79(10):1075-80. PMID: 24160802.
        View in: PubMed
      17. Huang J, Stewart A, Maity B, Hagen J, Fagan RL, Yang J, Quelle DE, Brenner C, Fisher RA. RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 degradation and promoting apoptosis. Oncogene. 2014 Jul 3; 33(27):3604-11. PMID: 23995786.
        View in: PubMed
      18. Greene CL, Demeester SR, Zehetner J, Worrell SG, Oh DS, Hagen J. Diaphragmatic relaxing incisions during laparoscopic paraesophageal hernia repair. Surg Endosc. 2013 Dec; 27(12):4532-8. PMID: 23949479.
        View in: PubMed
      19. Worrell SG, DeMeester SR, Greene CL, Oh DS, Hagen J. Pharyngeal pH monitoring better predicts a successful outcome for extraesophageal reflux symptoms after antireflux surgery. Surg Endosc. 2013 Nov; 27(11):4113-8. PMID: 23836124.
        View in: PubMed
      20. Oezcelik A, Ayazi S, DeMeester SR, Zehetner J, Abate E, Dunn J, Grant KS, Lipham JC, Hagen J, DeMeester TR. Adenocarcinoma of the esophagus in the young. J Gastrointest Surg. 2013 Jun; 17(6):1032-5. PMID: 23564309.
        View in: PubMed
      21. Hagen J. Invited commentary. Ann Thorac Surg. 2013 Feb; 95(2):463-4. PMID: 23336864.
        View in: PubMed
      22. Grant KS, DeMeester SR, Kreger V, Oh D, Hagen J, Chandrasoma P, DeMeester TR. Effect of Barrett's esophagus surveillance on esophageal preservation, tumor stage, and survival with esophageal adenocarcinoma. J Thorac Cardiovasc Surg. 2013 Jul; 146(1):31-7. PMID: 23312980.
        View in: PubMed
      23. Hagen J. Invited commentary. Ann Thorac Surg. 2012 Jun; 93(6):1854. PMID: 22632487.
        View in: PubMed
      24. Selamat SA, Chung BS, Girard L, Zhang W, Zhang Y, Campan M, Siegmund KD, Koss MN, Hagen J, Lam WL, Lam S, Gazdar AF, Laird-Offringa IA. Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression. Genome Res. 2012 Jul; 22(7):1197-211. PMID: 22613842.
        View in: PubMed
      25. Chandrasoma P, Wijetunge S, Demeester S, Ma Y, Hagen J, Zamis L, Demeester T. Columnar-lined esophagus without intestinal metaplasia has no proven risk of adenocarcinoma. Am J Surg Pathol. 2012 Jan; 36(1):1-7. PMID: 21959311.
        View in: PubMed
      26. Chandrasoma P, Wijetunge S, Ma Y, Demeester S, Hagen J, Demeester T. The dilated distal esophagus: a new entity that is the pathologic basis of early gastroesophageal reflux disease. Am J Surg Pathol. 2011 Dec; 35(12):1873-81. PMID: 21989338.
        View in: PubMed
      27. Hagen J. Invited commentary. Ann Thorac Surg. 2011 Dec; 92(6):2027. PMID: 22115213.
        View in: PubMed
      28. Theodorou D, Ayazi S, Demeester SR, Zehetner J, Peyre CG, Grant KS, Augustin F, Oh DS, Lipham JC, Chandrasoma PT, Hagen J, Demeester TR. Intraluminal pH and Goblet Cell Density in Barrett's Esophagus. J Gastrointest Surg. 2012 Mar; 16(3):469-74. PMID: 22095525.
        View in: PubMed
      29. Ayazi S, DeMeester SR, Hsieh CC, Zehetner J, Sharma G, Grant KS, Oh DS, Lipham JC, Hagen J, DeMeester TR. Thoraco-abdominal pressure gradients during the phases of respiration contribute to gastroesophageal reflux disease. Dig Dis Sci. 2011 Jun; 56(6):1718-22. PMID: 21512761.
        View in: PubMed
      30. Zehetner J, Demeester SR, Ayazi S, Kilday P, Augustin F, Hagen J, Lipham JC, Sohn HJ, Demeester TR. Laparoscopic versus open repair of paraesophageal hernia: the second decade. J Am Coll Surg. 2011 May; 212(5):813-20. PMID: 21435915.
        View in: PubMed
      31. Ayazi S, Hagen J, Zehetner J, Banki F, Augustin F, Ayazi A, DeMeester SR, Oh DS, Sohn HJ, Lipham JC, DeMeester TR. Day-to-day discrepancy in Bravo pH monitoring is related to the degree of deterioration of the lower esophageal sphincter and severity of reflux disease. Surg Endosc. 2011 Jul; 25(7):2219-23. PMID: 21359906.
        View in: PubMed
      32. Oh DS, DeMeester SR, Tanaka K, Marjoram P, Kuramochi H, Vallbohmer D, Danenberg K, Chandrasoma PT, DeMeester TR, Hagen J. The gene expression profile of cardia intestinal metaplasia is similar to that of Barrett's esophagus, not gastric intestinal metaplasia. Dis Esophagus. 2011 Sep; 24(7):516-22. PMID: 21309924.
        View in: PubMed
      33. Oezcelik A, DeMeester SR, Hindoyan K, Leers JM, Ayazi S, Abate E, Zehetner J, Hagen J, Lipham JC, DeMeester TR. Circular stapled pyloroplasty: a fast and effective technique for pyloric disruption during esophagectomy with gastric pull-up. Dis Esophagus. 2011 Aug; 24(6):423-9. PMID: 21309918.
        View in: PubMed
      34. Leers JM, DeMeester SR, Oezcelik A, Klipfel N, Ayazi S, Abate E, Zehetner J, Lipham JC, Chan L, Hagen J, DeMeester TR. The prevalence of lymph node metastases in patients with T1 esophageal adenocarcinoma a retrospective review of esophagectomy specimens. Ann Surg. 2011 Feb; 253(2):271-8. PMID: 21119508.
        View in: PubMed
      35. Zehetner J, DeMeester SR, Hagen J, Ayazi S, Augustin F, Lipham JC, DeMeester TR. Endoscopic resection and ablation versus esophagectomy for high-grade dysplasia and intramucosal adenocarcinoma. J Thorac Cardiovasc Surg. 2011 Jan; 141(1):39-47. PMID: 21055772.
        View in: PubMed
      36. Chandrasoma P, Wijetunge S, Demeester SR, Hagen J, Demeester TR. The histologic squamo-oxyntic gap: an accurate and reproducible diagnostic marker of gastroesophageal reflux disease. Am J Surg Pathol. 2010 Nov; 34(11):1574-81. PMID: 20871393.
        View in: PubMed
      37. Zehetner J, Lipham JC, Ayazi S, Banki F, Oezcelik A, DeMeester SR, Hagen J, DeMeester TR. Esophagectomy for cancer in octogenarians. Dis Esophagus. 2010 Nov; 23(8):666-9. PMID: 20545967.
        View in: PubMed
      38. Hagen J. Invited commentary. Ann Thorac Surg. 2010 Nov; 90(5):1667-8. PMID: 20971286.
        View in: PubMed
      39. Wijetunge S, Ma Y, DeMeester S, Hagen J, DeMeester T, Chandrasoma P. Association of adenocarcinomas of the distal esophagus, "gastroesophageal junction," and "gastric cardia" with gastric pathology. Am J Surg Pathol. 2010 Oct; 34(10):1521-7. PMID: 20871225.
        View in: PubMed
      40. Ayazi S, Hagen J, Zehetner J, Lilley M, Wali P, Augustin F, Oezcelik A, Sohn HJ, Lipham JC, Demeester SR, DeMeester TR. Loss of alkalization in proximal esophagus: a new diagnostic paradigm for patients with laryngopharyngeal reflux. J Gastrointest Surg. 2010 Nov; 14(11):1653-9. PMID: 20835772.
        View in: PubMed
      41. Zehetner J, DeMeester SR, Ayazi S, Costales JL, Augustin F, Oezcelik A, Lipham JC, Sohn HJ, Hagen J, DeMeester TR. Long-term follow-up after anti-reflux surgery in patients with Barrett's esophagus. J Gastrointest Surg. 2010 Oct; 14(10):1483-91. PMID: 20824377.
        View in: PubMed
      42. Ayazi S, Tamhankar A, DeMeester SR, Zehetner J, Wu C, Lipham JC, Hagen J, DeMeester TR. The impact of gastric distension on the lower esophageal sphincter and its exposure to acid gastric juice. Ann Surg. 2010 Jul; 252(1):57-62. PMID: 20562610.
        View in: PubMed
      43. Lurje G, Leers JM, Pohl A, Oezcelik A, Zhang W, Ayazi S, Winder T, Ning Y, Yang D, Klipfel NE, Chandrasoma P, Hagen J, DeMeester SR, DeMeester TR, Lenz HJ. Genetic variations in angiogenesis pathway genes predict tumor recurrence in localized adenocarcinoma of the esophagus. Ann Surg. 2010 May; 251(5):857-64. PMID: 20101173.
        View in: PubMed
      44. Abate E, DeMeester SR, Zehetner J, Oezcelik A, Ayazi S, Costales J, Banki F, Lipham JC, Hagen J, DeMeester TR. Recurrence after esophagectomy for adenocarcinoma: defining optimal follow-up intervals and testing. J Am Coll Surg. 2010 Apr; 210(4):428-35. PMID: 20347734.
        View in: PubMed
      45. Banki F, Flanagan P, Zehetner J, Armstrong A, Hagen J, Joshi A, Sinha R, Oh D, Oezcelik A, DeMeester SR, Abate E, Lipham JC, Chandrasoma P, Crookes PF, DeMeester TR. Progressive mucosal injury in patients with gastroesophageal reflux disease and increasing peripheral blood eosinophil counts. Arch Surg. 2010 Apr; 145(4):363-6. PMID: 20404287.
        View in: PubMed
      46. Ayazi S, Hagen J, Zehetner J, Oezcelik A, Abate E, Kohn GP, Sohn HJ, Lipham JC, Demeester SR, Demeester TR. Proximal esophageal pH monitoring: improved definition of normal values and determination of a composite pH score. J Am Coll Surg. 2010 Mar; 210(3):345-50. PMID: 20193899.
        View in: PubMed
      47. Oezcelik A, Banki F, Ayazi S, Abate E, Zehetner J, Sohn HJ, Hagen J, DeMeester SR, Lipham JC, Palmer SL, DeMeester TR. Detection of gastric conduit ischemia or anastomotic breakdown after cervical esophagogastrostomy: the use of computed tomography scan versus early endoscopy. Surg Endosc. 2010 Aug; 24(8):1948-51. PMID: 20135175.
        View in: PubMed
      48. Peyré SE, Peyré CG, Hagen J, Sullivan ME. Reliability of a procedural checklist as a high-stakes measurement of advanced technical skill. Am J Surg. 2010 Jan; 199(1):110-4. PMID: 20103075.
        View in: PubMed
      49. Ayazi S, Hagen J, Chandrasoma P, Gholami P, Zehetner J, Oezcelik A, Lipham JC, Demeester SR, Demeester TR, Kline MM. Esophageal intraepithelial eosinophils in dysphagic patients with gastroesophageal reflux disease. Dig Dis Sci. 2010 Apr; 55(4):967-72. PMID: 19960255.
        View in: PubMed
      50. Ayazi S, Hagen J, Zehetner J, Ross O, Wu C, Oezcelik A, Abate E, Sohn HJ, Banki F, Lipham JC, DeMeester SR, Demeester TR. The value of high-resolution manometry in the assessment of the resting characteristics of the lower esophageal sphincter. J Gastrointest Surg. 2009 Dec; 13(12):2113-20. PMID: 19779945.
        View in: PubMed
      51. Zehetner J, Lipham JC, Ayazi S, Oezcelik A, Abate E, Chen W, Demeester SR, Sohn HJ, Banki F, Hagen J, Dickey M, Demeester TR. A simplified technique for intrathoracic stomach repair: laparoscopic fundoplication with Vicryl mesh and BioGlue crural reinforcement. Surg Endosc. 2010 Mar; 24(3):675-9. PMID: 19690911.
        View in: PubMed
      52. Abate E, Banki F, Hagen J, Klipfel N. Giant cell tumor of the sternum. Ann Thorac Surg. 2009 Aug; 88(2):645-7. PMID: 19632429.
        View in: PubMed
      53. Leers JM, DeMeester SR, Chan N, Ayazi S, Oezcelik A, Abate E, Banki F, Lipham JC, Hagen J, DeMeester TR. Clinical characteristics, biologic behavior, and survival after esophagectomy are similar for adenocarcinoma of the gastroesophageal junction and the distal esophagus. J Thorac Cardiovasc Surg. 2009 Sep; 138(3):594-602; discussion 601-2. PMID: 19698841.
        View in: PubMed
      54. Ayazi S, Hagen J, Chan LS, DeMeester SR, Lin MW, Ayazi A, Leers JM, Oezcelik A, Banki F, Lipham JC, DeMeester TR, Crookes PF. Obesity and gastroesophageal reflux: quantifying the association between body mass index, esophageal acid exposure, and lower esophageal sphincter status in a large series of patients with reflux symptoms. J Gastrointest Surg. 2009 Aug; 13(8):1440-7. PMID: 19475461.
        View in: PubMed
      55. Ayazi S, Lipham JC, Hagen J, Tang AL, Zehetner J, Leers JM, Oezcelik A, Abate E, Banki F, DeMeester SR, DeMeester TR. A new technique for measurement of pharyngeal pH: normal values and discriminating pH threshold. J Gastrointest Surg. 2009 Aug; 13(8):1422-9. PMID: 19421822.
        View in: PubMed
      56. Oezcelik A, Banki F, DeMeester SR, Leers JM, Ayazi S, Abate E, Hagen J, Lipham JC, DeMeester TR. Delayed esophagogastrostomy: a safe strategy for management of patients with ischemic gastric conduit at time of esophagectomy. J Am Coll Surg. 2009 Jun; 208(6):1030-4. PMID: 19476888.
        View in: PubMed
      57. Chiu PW, Ayazi S, Hagen J, Lipham JC, Zehetner J, Abate E, Oezcelik A, Hsieh CC, DeMeester SR, Banki F, Chandrasoma P, DeMeester TR. Esophageal pH exposure and epithelial cell differentiation. Dis Esophagus. 2009; 22(7):596-9. PMID: 19392851.
        View in: PubMed
      58. Leers JM, Ayazi S, Hagen J, Terterov S, Klipfel N, Oezcelik A, Abate E, Lipham JC, DeMeester SR, Banki F, DeMeester TR. Survival in lymph node negative adenocarcinoma of the esophagus after R0 resection with and without neoadjuvant therapy: evidence for downstaging of N status. J Am Coll Surg. 2009 Apr; 208(4):553-6. PMID: 19476789.
        View in: PubMed
      59. Ayazi S, Leers JM, Oezcelik A, Abate E, Peyre CG, Hagen J, DeMeester SR, Banki F, Lipham JC, DeMeester TR, Crookes PF. Measurement of gastric pH in ambulatory esophageal pH monitoring. Surg Endosc. 2009 Sep; 23(9):1968-73. PMID: 19067071.
        View in: PubMed
      60. Peyre SE, Peyre CG, Hagen J, Sullivan ME, Lipham JC, Demeester SR, Peters JH, Demeester TR. Laparoscopic Nissen fundoplication assessment: task analysis as a model for the development of a procedural checklist. Surg Endosc. 2009 Jun; 23(6):1227-32. PMID: 19057949.
        View in: PubMed
      61. Lord RV, DeMeester SR, Peters JH, Hagen J, Elyssnia D, Sheth CT, DeMeester TR. Hiatal hernia, lower esophageal sphincter incompetence, and effectiveness of Nissen fundoplication in the spectrum of gastroesophageal reflux disease. J Gastrointest Surg. 2009 Apr; 13(4):602-10. PMID: 19050984.
        View in: PubMed
      62. Peyre CG, Hagen J, DeMeester SR, Van Lanschot JJ, Hölscher A, Law S, Ruol A, Ancona E, Griffin SM, Altorki NK, Rice TW, Wong J, Lerut T, DeMeester TR. Predicting systemic disease in patients with esophageal cancer after esophagectomy: a multinational study on the significance of the number of involved lymph nodes. Ann Surg. 2008 Dec; 248(6):979-85. PMID: 19092342.
        View in: PubMed
      63. Leers JM, DeMeester SR, Ayazi S, Tang AL, Peyre CG, Lipham JC, Hagen J, DeMeester TR. Recurrence of intramucosal esophageal adenocarcinoma arising in a former esophagostomy site: a unique case report. Dis Esophagus. 2009; 22(6):E17-20. PMID: 19021685.
        View in: PubMed
      64. Oezcelik A, Hagen J, Halls JM, Leers JM, Abate E, Ayazi S, Zehetner J, DeMeester SR, Banki F, Lipham JC, DeMeester TR. An improved method of assessing esophageal emptying using the timed barium study following surgical myotomy for achalasia. J Gastrointest Surg. 2009 Jan; 13(1):14-8. PMID: 18949523.
        View in: PubMed
      65. Peyre CG, Hagen J, DeMeester SR, Altorki NK, Ancona E, Griffin SM, Hölscher A, Lerut T, Law S, Rice TW, Ruol A, van Lanschot JJ, Wong J, DeMeester TR. The number of lymph nodes removed predicts survival in esophageal cancer: an international study on the impact of extent of surgical resection. Ann Surg. 2008 Oct; 248(4):549-56. PMID: 18936567.
        View in: PubMed
      66. Oh DS, DeMeester SR, Dunst CM, Mori R, Lehman BJ, Kuramochi H, Danenberg K, Danenberg P, Hagen J, Chandrasoma P, DeMeester TR. Validation of a rodent model of Barrett's esophagus using quantitative gene expression profiling. Surg Endosc. 2009 Jun; 23(6):1346-52. PMID: 18813976.
        View in: PubMed
      67. Ayazi S, Lipham JC, Portale G, Peyre CG, Streets CG, Leers JM, Demeester SR, Banki F, Chan LS, Hagen J, Demeester TR. Bravo catheter-free pH monitoring: normal values, concordance, optimal diagnostic thresholds, and accuracy. Clin Gastroenterol Hepatol. 2009 Jan; 7(1):60-7. PMID: 18976965.
        View in: PubMed
      68. Anglim PP, Galler JS, Koss MN, Hagen J, Turla S, Campan M, Weisenberger DJ, Laird PW, Siegmund KD, Laird-Offringa IA. Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer. Mol Cancer. 2008; 7:62. PMID: 18616821.
        View in: PubMed
      69. Rizzetto C, DeMeester SR, Hagen J, Peyre CG, Lipham JC, DeMeester TR. En bloc esophagectomy reduces local recurrence and improves survival compared with transhiatal resection after neoadjuvant therapy for esophageal adenocarcinoma. J Thorac Cardiovasc Surg. 2008 Jun; 135(6):1228-36. PMID: 18544359.
        View in: PubMed
      70. Banki F, Ayazi S, Hagen J, DeMeester SR, Lipham JC, Leers JM, Danenberg KD, Danenberg PV, DeMeester TR. Predictive value of preoperative plasma DNA level for early recurrence after resection in esophageal adenocarcinoma. J Clin Oncol. 2008 May 20; 26(15_suppl):4545. PMID: 27949135.
        View in: PubMed
      71. Banki F, Yacoub WN, Hagen J, Mason RJ, Ayazi S, DeMeester SR, Lipham JC, Danenberg K, Danenberg P, DeMeester TR. Plasma DNA is more reliable than carcinoembryonic antigen for diagnosis of recurrent esophageal cancer. J Am Coll Surg. 2008 Jul; 207(1):30-5. PMID: 18589358.
        View in: PubMed
      72. Rodrigo S, Abboud G, Oh D, DeMeester SR, Hagen J, Lipham J, DeMeester TR, Chandrasoma P. High intraepithelial eosinophil counts in esophageal squamous epithelium are not specific for eosinophilic esophagitis in adults. Am J Gastroenterol. 2008 Feb; 103(2):435-42. PMID: 18289205.
        View in: PubMed
      73. Banki F, Mason RJ, Hagen J, Demeester SR, Lipham JC, Danenberg K, Danenberg P, Demeester TR. Plasma DNA: a molecular marker of surgical insult and postoperative recovery in esophageal cancer. Eur Surg Res. 2008; 40(3):273-8. PMID: 18219202.
        View in: PubMed
      74. Tsou JA, Galler JS, Siegmund KD, Laird PW, Turla S, Cozen W, Hagen J, Koss MN, Laird-Offringa IA. Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma. Mol Cancer. 2007; 6:70. PMID: 17967182.
        View in: PubMed
      75. Peyre CG, DeMeester SR, Rizzetto C, Bansal N, Tang AL, Ayazi S, Leers JM, Lipham JC, Hagen J, DeMeester TR. Vagal-sparing esophagectomy: the ideal operation for intramucosal adenocarcinoma and barrett with high-grade dysplasia. Ann Surg. 2007 Oct; 246(4):665-71; discussion 671-4. PMID: 17893503.
        View in: PubMed
      76. Banki F, Mason RJ, Oh D, Hagen J, DeMeester SR, Lipham JC, Tanaka K, Danenberg KD, Yacoub WN, Danenberg PV, DeMeester TR. Plasma DNA as a molecular marker for completeness of resection and recurrent disease in patients with esophageal cancer. Arch Surg. 2007 Jun; 142(6):533-8; discussion 538-9. PMID: 17576889.
        View in: PubMed
      77. Oh DS, DeMeester SR, Vallbohmer D, Mori R, Kuramochi H, Hagen J, Lipham J, Danenberg KD, Danenberg PV, Chandrasoma P, DeMeester TR. Reduction of interleukin 8 gene expression in reflux esophagitis and Barrett's esophagus with antireflux surgery. Arch Surg. 2007 Jun; 142(6):554-9; discussion 559-60. PMID: 17576892.
        View in: PubMed
      78. Kerr KM, Galler JS, Hagen J, Laird PW, Laird-Offringa IA. The role of DNA methylation in the development and progression of lung adenocarcinoma. Dis Markers. 2007; 23(1-2):5-30. PMID: 17325423.
        View in: PubMed
      79. Portale G, Peters J, Hsieh CC, Tamhankar A, Arain M, Hagen J, DeMeester S, DeMeester T. When are reflux episodes symptomatic? Dis Esophagus. 2007; 20(1):47-52. PMID: 17227310.
        View in: PubMed
      80. Kanaan S, Boswell WD, Hagen J. Clinical and radiographic signs lead to early detection of lobar torsion and subsequent successful intervention. J Thorac Cardiovasc Surg. 2006 Sep; 132(3):720-1. PMID: 16935149.
        View in: PubMed
      81. Vallböhmer D, DeMeester SR, Oh DS, Banki F, Kuramochi H, Shimizu D, Hagen J, Danenberg KD, Danenberg PV, Chandrasoma PT, Peters JH, DeMeester TR. Antireflux surgery normalizes cyclooxygenase-2 expression in squamous epithelium of the distal esophagus. Am J Gastroenterol. 2006 Jul; 101(7):1458-66. PMID: 16863546.
        View in: PubMed
      82. Oh DS, Hagen J, Chandrasoma PT, Dunst CM, Demeester SR, Alavi M, Bremner CG, Lipham J, Rizzetto C, Cote R, Demeester TR. Clinical biology and surgical therapy of intramucosal adenocarcinoma of the esophagus. J Am Coll Surg. 2006 Aug; 203(2):152-61. PMID: 16864027.
        View in: PubMed
      83. Hamoui N, Lord RV, Hagen J, Theisen J, Demeester TR, Crookes PF. Response of the lower esophageal sphincter to gastric distention by carbonated beverages. J Gastrointest Surg. 2006 Jun; 10(6):870-7. PMID: 16769544.
        View in: PubMed
      84. Oh DS, Hagen J, Fein M, Bremner CG, Dunst CM, Demeester SR, Lipham J, Demeester TR. The impact of reflux composition on mucosal injury and esophageal function. J Gastrointest Surg. 2006 Jun; 10(6):787-96; discussion 796-7. PMID: 16769534.
        View in: PubMed
      85. Vallböhmer D, Peters JH, Kuramochi H, Oh D, Yang D, Shimizu D, DeMeester SR, Hagen J, Chandrasoma PT, Danenberg KD, Danenberg PV, DeMeester TR. Molecular determinants in targeted therapy for esophageal adenocarcinoma. Arch Surg. 2006 May; 141(5):476-81; discussion 481-2. PMID: 16702519.
        View in: PubMed
      86. Portale G, Hagen J, Peters JH, Chan LS, DeMeester SR, Gandamihardja TA, DeMeester TR. Modern 5-year survival of resectable esophageal adenocarcinoma: single institution experience with 263 patients. J Am Coll Surg. 2006 Apr; 202(4):588-96; discussion 596-8. PMID: 16571425.
        View in: PubMed
      87. Heestand G, Morrison B, Correa A, Palmer S, Mateo R, Hagen J, Genyk Y, Selby R, Sher L. Gallstone-induced inflammatory fibrosis: a relentless clinical course of retained gallstones after laparoscopic cholecystectomy. Am Surg. 2006 Apr; 72(4):303-6. PMID: 16676851.
        View in: PubMed
      88. Tharavej C, Hagen J, Portale G, Hsieh CC, Gandamihardja TA, Lipham JC, Peters JH, DeMeester SR, Crookes PF, Bremner CG, DeMeester TR. Bravo capsule induction of esophageal hypercontractility and chest pain. Surg Endosc. 2006 May; 20(5):783-6. PMID: 16544080.
        View in: PubMed
      89. Tharavej C, Hagen J, Peters JH, Portale G, Lipham J, DeMeester SR, Bremner CG, DeMeester TR. Predictive factors of coexisting cancer in Barrett's high-grade dysplasia. Surg Endosc. 2006 Mar; 20(3):439-43. PMID: 16437272.
        View in: PubMed
      90. Vallböhmer D, DeMeester SR, Peters JH, Oh DS, Kuramochi H, Shimizu D, Hagen J, Danenberg KD, Danenberg PV, DeMeester TR, Chandrasoma PT. Cdx-2 expression in squamous and metaplastic columnar epithelia of the esophagus. Dis Esophagus. 2006; 19(4):260-6. PMID: 16866857.
        View in: PubMed
      91. Portale G, Peters JH, Hsieh CC, Hagen J, DeMeester SR, DeMeester TR. Can clinical and endoscopic findings accurately predict early-stage adenocarcinoma? Surg Endosc. 2006 Feb; 20(2):294-7. PMID: 16333557.
        View in: PubMed
      92. Vallböhmer D, Peters JH, Oh D, Kuramochi H, Shimizu D, Demeester SR, Hagen J, Chandrasoma PT, Danenberg KD, DeMeester TR, Danenberg P. Survivin, a potential biomarker in the development of Barrett's adenocarcinoma. Surgery. 2005 Oct; 138(4):701-6; discussion 706-7. PMID: 16269299.
        View in: PubMed
      93. Maish MS, DeMeester SR, Choustoulakis E, Briel JW, Hagen J, Peters JH, Lipham JC, Bremner CG, DeMeester TR. The safety and usefulness of endoscopy for evaluation of the graft and anastomosis early after esophagectomy and reconstruction. Surg Endosc. 2005 Aug; 19(8):1093-102. PMID: 16027986.
        View in: PubMed
      94. Portale G, Peters JH, Hagen J, Demeester SR, Gandamihardja TA, Tharavej C, Hsieh CC, Demeester TR. Comparison of the clinical and histological characteristics and survival of distal esophageal-gastroesophageal junction adenocarcinoma in patients with and without barrett mucosa. Arch Surg. 2005 Jun; 140(6):570-4; discussion 574-5. PMID: 15967904.
        View in: PubMed
      95. Banki F, Demeester SR, Mason RJ, Campos G, Hagen J, Peters JH, Bremner CG, Demeester TR. Barrett's esophagus in females: a comparative analysis of risk factors in females and males. Am J Gastroenterol. 2005 Mar; 100(3):560-7. PMID: 15743352.
        View in: PubMed
      96. Tsou JA, Shen LY, Siegmund KD, Long TI, Laird PW, Seneviratne CK, Koss MN, Pass HI, Hagen J, Laird-Offringa IA. Distinct DNA methylation profiles in malignant mesothelioma, lung adenocarcinoma, and non-tumor lung. Lung Cancer. 2005 Feb; 47(2):193-204. PMID: 15639718.
        View in: PubMed
      97. Theisen J, Peters JH, Fein M, Hughes M, Hagen J, Demeester SR, Demeester TR, Laird PW. The mutagenic potential of duodenoesophageal reflux. Ann Surg. 2005 Jan; 241(1):63-8. PMID: 15621992.
        View in: PubMed
      98. Tamhankar AP, Peters JH, Portale G, Hsieh CC, Hagen J, Bremner CG, DeMeester TR. Omeprazole does not reduce gastroesophageal reflux: new insights using multichannel intraluminal impedance technology. J Gastrointest Surg. 2004 Nov; 8(7):890-7; discussion 897-8. PMID: 15531244.
        View in: PubMed
      99. Portale G, Peters JH, Hsieh CC, Tamhankar AP, Almogy G, Hagen J, Demeester SR, Bremner CG, Demeester TR. Esophageal adenocarcinoma in patients < or = 50 years old: delayed diagnosis and advanced disease at presentation. Am Surg. 2004 Nov; 70(11):954-8. PMID: 15586504.
        View in: PubMed
      100. Waterman TA, Hagen J, Peters JH, DeMeester SR, Taylor CR, Demeester TR. The prognostic importance of immunohistochemically detected node metastases in resected esophageal adenocarcinoma. Ann Thorac Surg. 2004 Oct; 78(4):1161-9; discussion 1161-9. PMID: 15464464.
        View in: PubMed
      101. Hamoui N, Peters JH, Schneider S, Uchida K, Yang D, Vallböhmer D, Valboehmer D, Hagen J, DeMeester SR, DeMeester TR, Danenberg K, Danenberg P. Increased acid exposure in patients with gastroesophageal reflux disease influences cyclooxygenase-2 gene expression in the squamous epithelium of the lower esophagus. Arch Surg. 2004 Jul; 139(7):712-6; discussion 716-7. PMID: 15249402.
        View in: PubMed
      102. Johansson J, DeMeester TR, Hagen J, DeMeester SR, Peters JH, Oberg S, Bremner CG. En bloc vs transhiatal esophagectomy for stage T3 N1 adenocarcinoma of the distal esophagus. Arch Surg. 2004 Jun; 139(6):627-31; discussion 631-3. PMID: 15197089.
        View in: PubMed
      103. Briel JW, Tamhankar AP, Hagen J, DeMeester SR, Johansson J, Choustoulakis E, Peters JH, Bremner CG, DeMeester TR. Prevalence and risk factors for ischemia, leak, and stricture of esophageal anastomosis: gastric pull-up versus colon interposition. J Am Coll Surg. 2004 Apr; 198(4):536-41; discussion 541-2. PMID: 15051003.
        View in: PubMed
      104. Arain MA, Peters JH, Tamhankar AP, Portale G, Almogy G, DeMeester SR, Crookes PF, Hagen J, Bremner CG, DeMeester TR. Preoperative lower esophageal sphincter pressure affects outcome of laparoscopic esophageal myotomy for achalasia. J Gastrointest Surg. 2004 Mar-Apr; 8(3):328-34. PMID: 15019930.
        View in: PubMed
      105. Theisen J, Nigro JJ, DeMeester TR, Peters JH, Gastal OL, Hagen J, Hashemi M, Bremner CG. Chronology of the Barrett's metaplasia-dysplasia-carcinoma sequence. Dis Esophagus. 2004; 17(1):67-70. PMID: 15209744.
        View in: PubMed
      106. Peters JH, Hagen J, DeMeester SR. Barrett's esophagus. J Gastrointest Surg. 2004 Jan; 8(1):1-17. PMID: 14746830.
        View in: PubMed
      107. Tamhankar AP, Almogy G, Arain MA, Portale G, Hagen J, Peters JH, Crookes PF, Sillin LF, DeMeester SR, Bremner CG, DeMeester TR. Surgical management of hypertensive lower esophageal sphincter with dysphagia or chest pain. J Gastrointest Surg. 2003 Dec; 7(8):990-6; discussion 996. PMID: 14675708.
        View in: PubMed
      108. Campos GM, Oberg S, Gastal O, Theisen J, Nigro JJ, Hagen J, Costantini M, Bremner CG, DeMeester TR, Crookes PF. Manometry of the lower esophageal sphincter: inter- and intraindividual variability of slow motorized pull-through versus station pull-through manometry. Dig Dis Sci. 2003 Jun; 48(6):1057-61. PMID: 12822862.
        View in: PubMed
      109. Hagen J, DeMeester TR. Staging of esophageal carcinoma. J Thorac Cardiovasc Surg. 2003 May; 125(5):988-91. PMID: 12771869.
        View in: PubMed
      110. Gurski RR, Peters JH, Hagen J, DeMeester SR, Bremner CG, Chandrasoma PT, DeMeester TR. Barrett's esophagus can and does regress after antireflux surgery: a study of prevalence and predictive features. J Am Coll Surg. 2003 May; 196(5):706-12; discussion 712-3. PMID: 12742201.
        View in: PubMed
      111. Balaji NS, DeMeester SR, Wickramasinghe KS, Hagen J, Peters JH, DeMeester TR. Etiology of intestinal metaplasia at the gastroesophageal junction. Surg Endosc. 2003 Jan; 17(1):43-8. PMID: 12364989.
        View in: PubMed
      112. DeMeester SR, Wickramasinghe KS, Lord RV, Friedman A, Balaji NS, Chandrasoma PT, Hagen J, Peters JH, DeMeester TR. Cytokeratin and DAS-1 immunostaining reveal similarities among cardiac mucosa, CIM, and Barrett's esophagus. Am J Gastroenterol. 2002 Oct; 97(10):2514-23. PMID: 12385432.
        View in: PubMed
      113. Streets CG, DeMeester SR, DeMeester TR, Peters JH, Hagen J, Crookes PF, Bremner CG. Excellent quality of life after Nissen fundoplication depends on successful elimination of reflux symptoms and not the invasiveness of the surgical approach. Ann Thorac Surg. 2002 Oct; 74(4):1019-24; discussion 1024-5. PMID: 12400739.
        View in: PubMed
      114. Banki F, Mason RJ, DeMeester SR, Hagen J, Balaji NS, Crookes PF, Bremner CG, Peters JH, DeMeester TR. Vagal-sparing esophagectomy: a more physiologic alternative. Ann Surg. 2002 Sep; 236(3):324-35; discussion 335-6. PMID: 12192319.
        View in: PubMed
      115. Tsou JA, Hagen J, Carpenter CL, Laird-Offringa IA. DNA methylation analysis: a powerful new tool for lung cancer diagnosis. Oncogene. 2002 Aug 12; 21(35):5450-61. PMID: 12154407.
        View in: PubMed
      116. Balaji NS, Crookes PF, Banki F, Hagen J, Ardill JE, DeMeester TR. A safe and noninvasive test for vagal integrity revisited. Arch Surg. 2002 Aug; 137(8):954-8; discussion 958-9. PMID: 12146997.
        View in: PubMed
      117. Lord RV, Kaminski A, Oberg S, Bowrey DJ, Hagen J, DeMeester SR, Sillin LF, Peters JH, Crookes PF, DeMeester TR. Absence of gastroesophageal reflux disease in a majority of patients taking acid suppression medications after Nissen fundoplication. J Gastrointest Surg. 2002 Jan-Feb; 6(1):3-9; discussion 10. PMID: 11986011.
        View in: PubMed
      118. Banki F, Mason RJ, Hagen J, Bremner CG, Streets CG, Peters JH, DeMeester TR. The crura and crura-sphincter pressure dynamics in patients with isolated upright and isolated supine reflux. Am Surg. 2001 Dec; 67(12):1150-6. PMID: 11768819.
        View in: PubMed
      119. Campos GM, DeMeester SR, Peters JH, Oberg S, Crookes PF, Hagen J, Bremner CG, Sillin LF, Mason RJ, DeMeester TR. Predictive factors of Barrett esophagus: multivariate analysis of 502 patients with gastroesophageal reflux disease. Arch Surg. 2001 Nov; 136(11):1267-73. PMID: 11695971.
        View in: PubMed
      120. Hagen J, DeMeester TR. Esophageal adenocarcinoma. Ann Thorac Surg. 2001 Oct; 72(4):1430-2. PMID: 11603490.
        View in: PubMed
      121. Hofstetter WL, Peters JH, DeMeester TR, Hagen J, DeMeester SR, Crookes PF, Tsai P, Banki F, Bremner CG. Long-term outcome of antireflux surgery in patients with Barrett's esophagus. Ann Surg. 2001 Oct; 234(4):532-8; discussion 538-9. PMID: 11573046.
        View in: PubMed
      122. Hagen J, DeMeester SR, Peters JH, Chandrasoma P, DeMeester TR. Curative resection for esophageal adenocarcinoma: analysis of 100 en bloc esophagectomies. Ann Surg. 2001 Oct; 234(4):520-30; discussion 530-1. PMID: 11573045.
        View in: PubMed
      123. Bowrey DJ, Blom D, Crookes PF, Bremner CG, Johansson JL, Lord RV, Hagen J, DeMeester SR, DeMeester TR, Peters JH. Risk factors and the prevalence of trocar site herniation after laparoscopic fundoplication. Surg Endosc. 2001 Jul; 15(7):663-6. PMID: 11591964.
        View in: PubMed
      124. Hagen J, Peters JH. Minimally invasive approaches to antireflux surgery. Semin Thorac Cardiovasc Surg. 2000 Jul; 12(3):157-72. PMID: 11052182.
        View in: PubMed
      125. Oberg S, Lord RV, Peters JH, Chandrasoma P, Theisen J, Hagen J, DeMeester SR, Bremner CG, DeMeester TR. Is adenocarcinoma following esophagoduodenostomy without carcinogen in the rat reflux-induced? J Surg Res. 2000 Jun 15; 91(2):111-7. PMID: 10839958.
        View in: PubMed
      126. Oberg S, Peters JH, DeMeester TR, Lord RV, Johansson J, DeMeester SR, Hagen J. Determinants of intestinal metaplasia within the columnar-lined esophagus. Arch Surg. 2000 Jun; 135(6):651-5; discussion 655-6. PMID: 10843360.
        View in: PubMed
      127. Lord RV, Crookes PF, Hagen J. Re: Editorial on outcomes of treatment for GERD. Am J Gastroenterol. 2000 May; 95(5):1362-4. PMID: 10811358.
        View in: PubMed
      128. Hashemi M, Peters JH, DeMeester TR, Huprich JE, Quek M, Hagen J, Crookes PF, Theisen J, DeMeester SR, Sillin LF, Bremner CG. Laparoscopic repair of large type III hiatal hernia: objective followup reveals high recurrence rate. J Am Coll Surg. 2000 May; 190(5):553-60; discussion 560-1. PMID: 10801022.
        View in: PubMed
      129. Lozoff B, Jimenez E, Hagen J, Mollen E, Wolf AW. Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy. Pediatrics. 2000 Apr; 105(4):E51. PMID: 10742372.
        View in: PubMed
      130. Theisen J, Nehra D, Citron D, Johansson J, Hagen J, Crookes PF, DeMeester SR, Bremner CG, DeMeester TR, Peters JH. Suppression of gastric acid secretion in patients with gastroesophageal reflux disease results in gastric bacterial overgrowth and deconjugation of bile acids. J Gastrointest Surg. 2000 Jan-Feb; 4(1):50-4. PMID: 10631362.
        View in: PubMed
      131. Fuller L, Huprich JE, Theisen J, Hagen J, Crookes PF, Demeester SR, Bremner CG, Demeester TR, Peters JH. Abnormal esophageal body function: radiographic-manometric correlation. Am Surg. 1999 Oct; 65(10):911-4. PMID: 10515533.
        View in: PubMed
      132. Nigro JJ, Hagen J, DeMeester TR, DeMeester SR, Theisen J, Peters JH, Kiyabu M. Occult esophageal adenocarcinoma: extent of disease and implications for effective therapy. Ann Surg. 1999 Sep; 230(3):433-8; discussion 438-40. PMID: 10493489.
        View in: PubMed
      133. Oberg S, Peters JH, Nigro JJ, Theisen J, Hagen J, DeMeester SR, Bremner CG, DeMeester TR. Helicobacter pylori is not associated with the manifestations of gastroesophageal reflux disease. Arch Surg. 1999 Jul; 134(7):722-6. PMID: 10401822.
        View in: PubMed
      134. Fein M, Ritter MP, DeMeester TR, Oberg S, Peters JH, Hagen J, Bremner CG. Role of the lower esophageal sphincter and hiatal hernia in the pathogenesis of gastroesophageal reflux disease. J Gastrointest Surg. 1999 Jul-Aug; 3(4):405-10. PMID: 10482693.
        View in: PubMed
      135. Gastal OL, Hagen J, Peters JH, Campos GM, Hashemi M, Theisen J, Bremner CG, DeMeester TR. Short esophagus: analysis of predictors and clinical implications. Arch Surg. 1999 Jun; 134(6):633-6; discussion 637-8. PMID: 10367873.
        View in: PubMed
      136. Campos GM, Peters JH, DeMeester TR, Oberg S, Crookes PF, Tan S, DeMeester SR, Hagen J, Bremner CG. Multivariate analysis of factors predicting outcome after laparoscopic Nissen fundoplication. J Gastrointest Surg. 1999 May-Jun; 3(3):292-300. PMID: 10481122.
        View in: PubMed
      137. Nigro JJ, DeMeester SR, Hagen J, DeMeester TR, Peters JH, Kiyabu M, Campos GM, Oberg S, Gastal O, Crookes PF, Bremner CG. Node status in transmural esophageal adenocarcinoma and outcome after en bloc esophagectomy. J Thorac Cardiovasc Surg. 1999 May; 117(5):960-8. PMID: 10220691.
        View in: PubMed
      138. Oberg S, DeMeester TR, Peters JH, Hagen J, Nigro JJ, DeMeester SR, Theisen J, Campos GM, Crookes PF. The extent of Barrett's esophagus depends on the status of the lower esophageal sphincter and the degree of esophageal acid exposure. J Thorac Cardiovasc Surg. 1999 Mar; 117(3):572-80. PMID: 10047662.
        View in: PubMed
      139. Nigro JJ, Hagen J, DeMeester TR, DeMeester SR, Peters JH, Oberg S, Theisen J, Kiyabu M, Crookes PF, Bremner CG. Prevalence and location of nodal metastases in distal esophageal adenocarcinoma confined to the wall: implications for therapy. J Thorac Cardiovasc Surg. 1999 Jan; 117(1):16-23; discussion 23-5. PMID: 9869753.
        View in: PubMed
      140. Mason RJ, Bremner CG, DeMeester TR, Crookes PF, Peters JH, Hagen J, DeMeester SR. Pharyngeal swallowing disorders: selection for and outcome after myotomy. Ann Surg. 1998 Oct; 228(4):598-608. PMID: 9790349.
        View in: PubMed
      141. DeMeester SR, Campos GM, DeMeester TR, Bremner CG, Hagen J, Peters JH, Crookes PF. The impact of an antireflux procedure on intestinal metaplasia of the cardia. Ann Surg. 1998 Oct; 228(4):547-56. PMID: 9790344.
        View in: PubMed
      142. Barr ML, Schenkel FA, Cohen RG, Barbers RG, Fuller CB, Hagen J, Wells WJ, Starnes VA. Recipient and donor outcomes in living related and unrelated lobar transplantation. Transplant Proc. 1998 Aug; 30(5):2261-3. PMID: 9723463.
        View in: PubMed
      143. Peters JH, DeMeester TR, Crookes P, Oberg S, de Vos Shoop M, Hagen J, Bremner CG. The treatment of gastroesophageal reflux disease with laparoscopic Nissen fundoplication: prospective evaluation of 100 patients with "typical" symptoms. Ann Surg. 1998 Jul; 228(1):40-50. PMID: 9671065.
        View in: PubMed
      144. Watson TJ, DeMeester TR, Kauer WK, Peters JH, Hagen J. Esophageal replacement for end-stage benign esophageal disease. J Thorac Cardiovasc Surg. 1998 Jun; 115(6):1241-7; discussion 1247-9. PMID: 9628664.
        View in: PubMed
      145. Fein M, Peters JH, Chandrasoma P, Ireland AP, Oberg S, Ritter MP, Bremner CG, Hagen J, DeMeester TR. Duodenoesophageal reflux induces esophageal adenocarcinoma without exogenous carcinogen. J Gastrointest Surg. 1998 May-Jun; 2(3):260-8. PMID: 9841983.
        View in: PubMed
      146. Ritter MP, Peters JH, DeMeester TR, Gadenstätter M, Oberg S, Fein M, Hagen J, Crookes PF, Bremner CG. Treatment of advanced gastroesophageal reflux disease with Collis gastroplasty and Belsey partial fundoplication. Arch Surg. 1998 May; 133(5):523-8; discussion 528-9. PMID: 9605915.
        View in: PubMed
      147. Bremner RM, Mason RJ, Bremner CG, DeMeester TR, Chandrasoma P, Peters JH, Hagen J, Gadenstätter M. Ultrasonic epithelial ablation of the lower esophagus without stricture formation. A new technique for Barrett's ablation. Surg Endosc. 1998 Apr; 12(4):342-6; discussion 346-7. PMID: 9543526.
        View in: PubMed
      148. Bremner RM, Costantini M, DeMeester TR, Bremner CG, Hoeft SF, Crookes PF, Peters JH, Hagen J. Normal esophageal body function: a study using ambulatory esophageal manometry. Am J Gastroenterol. 1998 Feb; 93(2):183-7. PMID: 9468238.
        View in: PubMed
      149. Gadenstätter M, Hagen J, DeMeester TR, Ritter MP, Peters JH, Mason RJ, Crookes PF. Esophagectomy for unsuccessful antireflux operations. J Thorac Cardiovasc Surg. 1998 Feb; 115(2):296-300, 302; discussion 300-1. PMID: 9475523.
        View in: PubMed
      150. Starnes VA, Barr ML, Schenkel FA, Horn MV, Cohen RG, Hagen J, Wells WJ. Experience with living-donor lobar transplantation for indications other than cystic fibrosis. J Thorac Cardiovasc Surg. 1997 Dec; 114(6):917-21; discussion 921-2. PMID: 9434686.
        View in: PubMed
      151. Oberg S, Peters JH, DeMeester TR, Chandrasoma P, Hagen J, Ireland AP, Ritter MP, Mason RJ, Crookes P, Bremner CG. Inflammation and specialized intestinal metaplasia of cardiac mucosa is a manifestation of gastroesophageal reflux disease. Ann Surg. 1997 Oct; 226(4):522-30; discussion 530-2. PMID: 9351720.
        View in: PubMed
      152. Fein M, Hagen J, Ritter MP, DeMeester TR, De Vos M, Bremner CG, Peters JH. Isolated upright gastroesophageal reflux is not a contraindication for antireflux surgery. Surgery. 1997 Oct; 122(4):829-35. PMID: 9347863.
        View in: PubMed
      153. Tefera L, Fein M, Ritter MP, Bremner CG, Crookes PF, Peters JH, Hagen J, DeMeester TR. Can the combination of symptoms and endoscopy confirm the presence of gastroesophageal reflux disease? Am Surg. 1997 Oct; 63(10):933-6. PMID: 9322676.
        View in: PubMed
      154. Hagen J. Management of Barrett's esophagus with dysplasia. Semin Thorac Cardiovasc Surg. 1997 Jul; 9(3):285-9. PMID: 9263347.
        View in: PubMed
      155. Mason RJ, DeMeester TR, Lund RJ, Peters JH, Crookes P, Ritter M, Gadenstätter M, Hagen J. Nissen fundoplication prevents shortening of the sphincter during gastric distention. Arch Surg. 1997 Jul; 132(7):719-24; discussion 724-6. PMID: 9230855.
        View in: PubMed
      156. Kvaerner KJ, Nafstad P, Hagen J, Mair IW, Jaakkola JJ. Recurrent acute otitis media: the significance of age at onset. Acta Otolaryngol. 1997 Jul; 117(4):578-84. PMID: 9288216.
        View in: PubMed
      157. Nafstad P, Jaakkola JJ, Hagen J, Zahlsen K, Magnus P. Hair nicotine concentrations in mothers and children in relation to parental smoking. J Expo Anal Environ Epidemiol. 1997 Apr-Jun; 7(2):235-9. PMID: 9185014.
        View in: PubMed
      158. Fein M, Ireland AP, Ritter MP, Peters JH, Hagen J, Bremner CG, DeMeester TR. Duodenogastric reflux potentiates the injurious effects of gastroesophageal reflux. J Gastrointest Surg. 1997 Jan-Feb; 1(1):27-32; discussion 33. PMID: 9834327.
        View in: PubMed
      159. Kvaerner KJ, Nafstad P, Hagen J, Mair IW, Jaakkola JJ. Early acute otitis media: determined by exposure to respiratory pathogens. Acta Otolaryngol Suppl. 1997; 529:14-8. PMID: 9288257.
        View in: PubMed
      160. Nafstad P, Jaakkola JJ, Hagen J, Botten G, Kongerud J. Breastfeeding, maternal smoking and lower respiratory tract infections. Eur Respir J. 1996 Dec; 9(12):2623-9. PMID: 8980979.
        View in: PubMed
      161. Starnes VA, Barr ML, Cohen RG, Hagen J, Wells WJ, Horn MV, Schenkel FA. Living-donor lobar lung transplantation experience: intermediate results. J Thorac Cardiovasc Surg. 1996 Nov; 112(5):1284-90; discussion 1290-1. PMID: 8911325.
        View in: PubMed
      162. Cohen RG, Shely WW, Thompson SE, Hagen J, Marboe CC, DeMeester TR, Starnes VA. Talc pleurodesis: talc slurry versus thoracoscopic talc insufflation in a porcine model. Ann Thorac Surg. 1996 Oct; 62(4):1000-2; discussion 1003-4. PMID: 8823079.
        View in: PubMed
      163. Barr ML, Schenkel FA, Cohen RG, Chan KM, Marboe CC, Hagen J, Barbers RG, Starnes VA. Bilateral lobar transplantation utilizing living related donors. Artif Organs. 1996 Oct; 20(10):1110-1. PMID: 8896729.
        View in: PubMed
      164. Johnson WE, Hagen J, DeMeester TR, Kauer WK, Ritter MP, Peters JH, Bremner CG. Outcome of respiratory symptoms after antireflux surgery on patients with gastroesophageal reflux disease. Arch Surg. 1996 May; 131(5):489-92. PMID: 8624193.
        View in: PubMed
      165. Fuller CB, Hagen J, DeMeester TR, Peters JH, Ritter M, Bremmer CG. The role of fundoplication in the treatment of type II paraesophageal hernia. J Thorac Cardiovasc Surg. 1996 Mar; 111(3):655-61. PMID: 8601982.
        View in: PubMed
      166. Clark GW, Ireland AP, Hagen J, Collard JM, Peters JH, DeMeester TR. Carcinoembryonic antigen measurements in the management of esophageal cancer: an indicator of subclinical recurrence. Am J Surg. 1995 Dec; 170(6):597-600; discussion 600-1. PMID: 7492008.
        View in: PubMed
      167. Kauer WK, Peters JH, DeMeester TR, Ireland AP, Bremner CG, Hagen J. Mixed reflux of gastric and duodenal juices is more harmful to the esophagus than gastric juice alone. The need for surgical therapy re-emphasized. Ann Surg. 1995 Oct; 222(4):525-31; discussion 531-3. PMID: 7574932.
        View in: PubMed
      168. Clark GW, Peters JH, Ireland AP, Ehsan A, Hagen J, Kiyabu MT, Bremner CG, DeMeester TR. Nodal metastasis and sites of recurrence after en bloc esophagectomy for adenocarcinoma. Ann Thorac Surg. 1994 Sep; 58(3):646-53; discussion 653-4. PMID: 7944684.
        View in: PubMed
      169. Bremner RM, DeMeester TR, Crookes PF, Costantini M, Hoeft SF, Peters JH, Hagen J. The effect of symptoms and nonspecific motility abnormalities on outcomes of surgical therapy for gastroesophageal reflux disease. J Thorac Cardiovasc Surg. 1994 May; 107(5):1244-9; discussion 1249-50. PMID: 8176967.
        View in: PubMed
      170. Hagen J, Peters JH, DeMeester TR. Superiority of extended en bloc esophagogastrectomy for carcinoma of the lower esophagus and cardia. J Thorac Cardiovasc Surg. 1993 Nov; 106(5):850-8; discussion 858-9. PMID: 8231207.
        View in: PubMed
      171. Albertucci M, DeMeester TR, Rothberg M, Hagen J, Santoscoy R, Smyrk TC. Surgery and the management of peripheral lung tumors adherent to the parietal pleura. J Thorac Cardiovasc Surg. 1992 Jan; 103(1):8-12; discussion 12-3. PMID: 1309467.
        View in: PubMed
      172. Martyn JA, Greenblatt DJ, Hagen J, Hoaglin DC. Alteration by burn injury of the pharmacokinetics and pharmacodynamics of cimetidine in children. Eur J Clin Pharmacol. 1989; 36(4):361-7. PMID: 2737228.
        View in: PubMed
      173. Deitel M, Khanna RK, Hagen J, Ilves R. Vertical banded gastroplasty as an antireflux procedure. Am J Surg. 1988 Mar; 155(3):512-6. PMID: 3344920.
        View in: PubMed
      174. Hagen J, Deitel M, Khanna RK, Ilves R. Gastroesophageal reflux in the massively obese. Int Surg. 1987 Jan-Mar; 72(1):1-3. PMID: 3596968.
        View in: PubMed
      175. Berk J, Hagen J, Levy M. The cardiovascular action of oxygen breathing: effect on adrenergic stimulation. Eur Surg Res. 1983; 15(4):185-92. PMID: 6873116.
        View in: PubMed