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    Gianluca Lazzi

    TitleProfessor of Ophthalmology and Electrical Engineering
    SchoolKeck School of Medicine of USC
    DepartmentOphthalmology
    Address1537 Norfolk St.
    Off Campus
    Los Angeles California 90033
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      Collapse Overview 
      Collapse Overview
      Over the past 25 years, Gianluca Lazzi, PhD, has focused his research on biomedical electromagnetics, with particular interest to the application to wireless and biomedical devices. In the early stages of his career, he focused on understanding the interaction between electromagnetic fields and biological tissue, with particular interest in the potential hazards to the human body due to devices radiating or inducing electromagnetic fields in tissue. Lazzi's research contributed to define the computational methods that could be reliably used to assess the Specific Absorption Rate of power, or SAR, induced by wireless devices in the human body: this work directly impacted the acceptance of computational methods to demonstrate that wireless devices previously fulfilled IEEE safety standards prior to being marketed.

      The computational and experimental methods that Lazzi and his team developed progressively shifted to be used for medical device applications, and in particular an artificial retina to restore partial vision to the blind and hippocampal prosthesis. Lazzi has also been recognized for multiscale computational methods to calculate the electromagnetic distribution in neural tissue for optimization of neurostimulators, human body models for the safety assessment of wireless biomedical devices, implantable microantennas for high-data rate wireless biomedical devices, novel coils for wireless telemetry systems, methods for the minimization of the temperature increase in the human body due to implantable devices, and methods to optimize electrode shape and size for neurosimulators. For nearly 20 years, Lazzi and his team have been part of a team dedicated to the development a retinal prosthesis to restore partial vision to the blind, in collaboration with the company Second Sight Medical Products, Inc. He also been part of an NSF supported Engineering Research Center (ERC) on Biomimetic Devices led by the University of Southern California. Lazzi's contributions in the field of implantable devices have been recognized with the election as AIMBE Fellow for “contributions to bioelectromagnetics and design of bioelectrical implantable devices,” election as a IEEE Fellow for “contributions to Bioelectromagnetics and implantable devices,” the IEEE Wheeler Best paper Award for a manuscript on the invention of microwave microantennas for implantable devices, and a R&D100 Award in 2009 for one of the 100 most significant inventions of 2009 (artificial retina). His team recently presented research on neuroprosthetics and multiscale modeling at the IEEE Grand Challenges in Life Science Symposium at the National Academies: parts of this inspired a position paper on the future grand challenges in life science published in IEEE Trans. on Biomedical Engineering, jointly prepared by all the presenters.


      Collapse Biography 
      Collapse Education and Training
      University of Rome "La Sapienza", Rome, ITDr. Eng.1994Electronic Engineering
      University of Utah, Salt Lake City, UTPhD1998Electrical Engineering
      IE Business School, Madrid ESPMBA2015Business Administration
      Collapse Awards and Honors
      Bioelectromagnetics Society1996Curtis Carl Johnson Memorial Award
      International Union of Radio Science1996Young Investigator Award
      National Science Foundation2001Career Award
      The Whitaker Foundation Biomedical Engineering Grant2001Young Investigator Award
      North Carolina State University2003Outstanding Teacher Award
      North Carolina State University2003Alumni Outstanding Teacher Award
      North Carolina State University2003ALCOA Foundation Engineering Research Achievement Award
      North Carolina State University2003Featured Achiever, College of Engineering
      IEEE Trans.2005IEEE H.A. Wheeler Award for the best paper published
      IEEE Trans.2006IEEE H.A. Wheeler Award for best paper published
      IEEE GLOBECOM2008Best Paper Award
      IEEE2008Fellow, "Contributions to Bioelectromagnetics and Implantable Devices"
      North Carolina State University2009ALCOA Foundation Distinguished Engineering Research Achievement Award
      R&D Magazine2009R&D 100 Award and Editor's Choice Award
      AIMBE2015Fellow, "Contributions to Bioelectromagnetics and Design of Bioelectrical Implantable Devices"

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Loizos K, RamRakhyani AK, Anderson J, Marc R, Lazzi G. On the computation of a retina resistivity profile for applications in multi-scale modeling of electrical stimulation and absorption. Phys Med Biol. 2016 Jun 21; 61(12):4491-505. PMID: 27223656; PMCID: PMC4916774.
      2. Loizos K, Cela C, Marc R, Lazzi G. Virtual electrode design for increasing spatial resolution in retinal prosthesis. Healthc Technol Lett. 2016 Jun; 3(2):93-7. PMID: 27382477; PMCID: PMC4916480 [Available on 04/27/17].
      3. Kagan ZB, RamRakhyani AK, Lazzi G, Normann RA, Warren DJ. In Vivo Magnetic Stimulation of Rat Sciatic Nerve With Centimeter- and Millimeter-Scale Solenoid Coils. IEEE Trans Neural Syst Rehabil Eng. 2016 Nov; 24(11):1138-1147. PMID: 27019496.
        View in: PubMed
      4. Kagan Z, RamRakhyani A, Lazzi G, Normann R, Warren D. In Vivo Magnetic Stimulation of Rat Sciatic Nerve with Centimeter- and Millimeter-Scale Solenoid Coils. IEEE Trans Neural Syst Rehabil Eng. 2016 Mar 21. PMID: 28113861.
        View in: PubMed
      5. RamRakhyani AK, Kagan ZB, Warren DJ, Normann RA, Lazzi G. A µm-Scale Computational Model of Magnetic Neural Stimulation in Multifascicular Peripheral Nerves. IEEE Trans Biomed Eng. 2015 Dec; 62(12):2837-49. PMID: 26087483.
        View in: PubMed
      6. Gilbert A, Loizos K, RamRakhyani AK, Hendrickson P, Lazzi G, Berger TW. A 3-D admittance-level computational model of a rat hippocampus for improving prosthetic design. Conf Proc IEEE Eng Med Biol Soc. 2015; 2015:2295-8. PMID: 26736751; PMCID: PMC4877026.
      7. RamRakhyani AK, Lazzi G. Ferrite core non-linearity in coils for magnetic neurostimulation. Healthc Technol Lett. 2014 Oct; 1(4):87-91. PMID: 26609390; PMCID: PMC4614077 [Available on 12/16/15].
      8. RamRakhyani AK, Lazzi G. Multi-coil approach to reduce electromagnetic energy absorption for wirelessly powered implants. Healthc Technol Lett. 2014 Jan; 1(1):21-5. PMID: 26609371; PMCID: PMC4614348.
      9. Kagan ZB, RamRakhyani AK, Khan F, Lazzi G, Normann RA, Warren DJ. Magnetic stimulation of mammalian peripheral nerves in vivo: an alternative to functional electrical stimulation. Conf Proc IEEE Eng Med Biol Soc. 2014; 2014:2573-6. PMID: 25570516.
        View in: PubMed
      10. RamRakhyani AK, Kagan ZB, Khan F, Warren DJ, Normann RA, Lazzi G. A µm-resolution heterogeneous tissue model for the magnetic stimulation of multifascicular sciatic nerve. Conf Proc IEEE Eng Med Biol Soc. 2014; 2014:5679-82. PMID: 25571284.
        View in: PubMed
      11. Loizos K, Lazzi G, Lauritzen JS, Anderson J, Jones BW, Marc R. A multi-scale computational model for the study of retinal prosthetic stimulation. Conf Proc IEEE Eng Med Biol Soc. 2014; 2014:6100-3. PMID: 25571389; PMCID: PMC4490688.
      12. Ramrakhyani AK, Lazzi G. On the design of efficient multi-coil telemetry system for biomedical implants. IEEE Trans Biomed Circuits Syst. 2013 Feb; 7(1):11-23. PMID: 23853275.
        View in: PubMed
      13. He B, Baird R, Butera R, Datta A, George S, Hecht B, Hero A, Lazzi G, Lee RC, Liang J, Neuman M, Peng GC, Perreault EJ, Ramasubramanian M, Wang MD, Wikswo J, Yang GZ, Zhang YT. Grand challenges in interfacing engineering with life sciences and medicine. IEEE Trans Biomed Eng. 2013 Mar; 60(3):589-98. PMID: 23380847.
        View in: PubMed
      14. Xie J, Wang GJ, Yow L, Humayun MS, Weiland JD, Cela CJ, Jadvar H, Lazzi G, Dhrami-Gavazi E, Tsang SH. Preservation of retinotopic map in retinal degeneration. Exp Eye Res. 2012 May; 98:88-96. PMID: 22685713; PMCID: PMC4310463.
      15. Cela CJ, Lee RC, Lazzi G. Modeling cellular lysis in skeletal muscle due to electric shock. IEEE Trans Biomed Eng. 2011 May; 58(5):1286-93. PMID: 21216705.
        View in: PubMed
      16. Xie J, Wang GJ, Yow L, J Cela C, Humayun MS, Weiland JD, Lazzi G, Jadvar H. Modeling and percept of transcorneal electrical stimulation in humans. IEEE Trans Biomed Eng. 2011 Jul; 58(7):1932-9. PMID: 20952323.
        View in: PubMed
      17. Kandagor V, Cela CJ, Sanders CA, Greenbaum E, Lazzi G, Humayun MS, Zhou DM, Castro R, Gaikwad S, Little J. Spatial characterization of electric potentials generated by pulsed microelectrode arrays. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:6243-6. PMID: 21097346.
        View in: PubMed
      18. Singh V, Roy A, Castro R, McClure K, Dai R, Agrawal R, Greenberg RJ, Weiland JD, Humayun MS, Lazzi G. On the thermal elevation of a 60-electrode epiretinal prosthesis for the blind. IEEE Trans Biomed Circuits Syst. 2008 Dec; 2(4):289-300. PMID: 23853132.
        View in: PubMed
      19. Lazzi G. Thermal effects of bioimplants. IEEE Eng Med Biol Mag. 2005 Sep-Oct; 24(5):75-81. PMID: 16248120.
        View in: PubMed
      20. Gosalia K, Weiland J, Humayun M, Lazzi G. Thermal elevation in the human eye and head due to the operation of a retinal prosthesis. IEEE Trans Biomed Eng. 2004 Aug; 51(8):1469-77. PMID: 15311834.
        View in: PubMed
      21. Eberdt M, Brown PK, Lazzi G. Two-dimensional SPICE-linked multiresolution impedance method for low-frequency electromagnetic interactions. IEEE Trans Biomed Eng. 2003 Jul; 50(7):881-9. PMID: 12848356.
        View in: PubMed
      22. Margalit E, Maia M, Weiland JD, Greenberg RJ, Fujii GY, Torres G, Piyathaisere DV, O'Hearn TM, Liu W, Lazzi G, Dagnelie G, Scribner DA, de Juan E, Humayun MS. Retinal prosthesis for the blind. Surv Ophthalmol. 2002 Jul-Aug; 47(4):335-56. PMID: 12161210.
        View in: PubMed
      23. Gandhi OP, Kang G, Wu D, Lazzi G. Currents induced in anatomic models of the human for uniform and nonuniform power frequency magnetic fields. Bioelectromagnetics. 2001 Feb; 22(2):112-21. PMID: 11180257.
        View in: PubMed
      24. Gandhi OP, Lazzi G, Tinniswood A, Yu QS. Comparison of numerical and experimental methods for determination of SAR and radiation patterns of handheld wireless telephones. Bioelectromagnetics. 1999; Suppl 4:93-101. PMID: 10334718.
        View in: PubMed
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