As an environmental epidemiologist, I lead an interdisciplinary program of research focused on understanding the long-term health risks for cardiovascular, respiratory and metabolic diseases resulting from the interplay between early-life environmental exposures, susceptibility factors, and biological mechanisms. I co-direct the Maternal And Developmental Risks from Environmental and Social Stressors (MADRES) Center located in the Environmental Health Division. Within the Center, my work addresses the interplay between environmental health inequities, social stressors, and epigenetic mechanisms underlying child health outcomes. I take multigenerational approach to examine whether pre- and postpartum environmental exposures such as air pollution, tobacco smoke, heavy metals and chemical exposures, coupled with exposures to psychosocial and built environment stressors, affect birth outcomes, perturbed infant growth trajectories and increased childhood obesity risk. Additional work has investigated how environmental exposures alter epigenetic profiles in pregnancy and in newborns and young children, and what roles those changes play in responding to environmental exposures and driving disease risk, particularly in vulnerable populations. I has conducted both epigenome-wide and targeted epigenomic investigations, as well as multi-generational investigations, to better understand the roles of DNA methylation and miRNA underlying environment health effects.